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129 Studies found from all possible combinations of your search terms. Select a protocol that you wish to review.
Protocol Number Title Protocol Status Min-Max Age Institute Keywords
21-I-0003A Phase 1/2 Study to Evaluate the Safety, Tolerability and Efficacy, of JSP191 for Hematopoietic Cell Transplantation Conditioning to Achieve Engraftment and Immune Reconstitution in Subjects with SCIDParticipants currently recruited/enrolled3-125 YearsNIAIDCombined Immunodeficiency
19-CC-0063Impact of Steady State Cobicistat and Darunavir/Cobicistat on the Pharmacokinetics and Pharmacodynamics of Oral Anticoagulants (Rivaroxaban, Apixaban) in Healthy VolunteersCompleted Study; data analyses ongoing18-65 YearsCC Combined Immunodeficiency
18-I-0041Investigating the Mechanistic Biology of Primary Immunodeficiency DisordersParticipants currently recruited/enrolled0-75 YearsNIAIDCombined Immunodeficiency
11-I-0007Lentiviral Gene Transfer for Treatment of Children Older Than 2 Years of Age with X-Linked Severe Combined ImmunodeficiencyParticipants currently recruited/enrolled2-40 YearsNIAIDCombined Immunodeficiency
09-I-0133Establishing Fibroblast-derived Cell Lines from Skin/Tissue Biopsies of Patients with Immunodeficiency or Immunodysregulation DisordersEnrolling by Invitation2-85 YearsNIAIDCombined Immunodeficiency
05-I-0213Screening and Baseline Assessment of Patients with Abnormalities of Immune FunctionParticipants currently recruited/enrolled0-125 YearsNIAIDCombined Immunodeficiency
03-H-0105The Determination of Genetic Basis Of ImmunodeficiencyParticipants currently recruited/enrolled0-99 YearsNHLBICombined Immunodeficiency
00-I-0159Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection Syndrome (HIES)Participants currently recruited/enrolled0-120 YearsNIAIDCombined Immunodeficiency
002090-CComboMATCH Treatment Trial N5: Randomized Trial of Neratinib, a Pan-ErbB Inhibitor alone or in combination with Palbociclib, a CDK4/6 Inhibitor, in Patients with HER2+ Gynecologic Cancers and other Solid TumorsParticipants currently recruited/enrolled18-120 YearsNCI Combined
002041-CPhase 2 Trial of the Combination of the BET inhibitor, ZEN003694 (ZEN-3694), and the PARP Inhibitor Talazoparib, in Patients with Molecularly-Selected Solid Tumors (ComBET)Recruitment has not started18-120 YearsNCI Combined
001979-IA Pilot Phase 2 Study of the Safety and Efficacy of Dupilumab as Add-on Therapy for Hypereosinophilic Syndrome with Partial Clinical Response to Eosinophil-Depleting Biologic AgentsRecruitment has not started18-99 YearsNIAIDCombined
001827-CPhase 3, Multicenter, Randomized, Open-Label Study to Assess the Efficacy and Safety Of the Lifileucel (LN-144), Autologous Tumor-Infiltrating Lymphocytes [TIL]) Regimen in Combination with Pembrolizumab Compared with Pembrolizumab Monotherapy in ParticiRecruitment has not started18-70 YearsNCI Combined
001778-CA Randomized, Open Label, Two-Arm, Multicenter Phase 2 Study to Evaluate Efficacy and Safety of PRGN-2009 in Combination with Pembrolizumab Versus Pembrolizumab Monotherapy in Patients with Recurrent or Metastatic Cervical CancerParticipants currently recruited/enrolled18-120 YearsNCI Combined
001771-CEAY191-S3, Phase II Study of Paclitaxel (NSC #673089) + Ipatasertib (NSC #781451) in Taxane-Refractory Participants With AKT-Altered Advanced Non-Breast Solid Tumors (A ComboMATCH Treatment Trial)Participants currently recruited/enrolled18-100 YearsNCI Combined
001770-CMolecular Analysis for Combination Therapy Choice (ComboMATCH) EAY191-N4: A Randomized Trial of Selumetinib and Olaparib or Selumetinib Alone in Patients With Recurrent or Persistent RAS Pathway Mutant Ovarian and Endometrial CancersParticipants currently recruited/enrolled18-120 YearsNCI Combined
001756-CA Phase 1 Study of Peposertib (M3814) and Low-Dose Liposomal Doxorubicin in Patients with Metastatic Leiomyosarcoma and Other Soft Tissue SarcomasParticipants currently recruited/enrolled18-120 YearsNCI Combined
001749-CComboMATCH Treatment Trial E4: Nilotinib and Paclitaxel in Patients with Prior Taxane-Treated Solid TumorsParticipants currently recruited/enrolled18-120 YearsNCI Combined
001733-CA Phase 1 Clinical Trial of CA-4948 in Combination with Gemcitabine and Nab-Paclitaxel in Metastatic or Unresectable Pancreatic Ductal CarcinomaParticipants currently recruited/enrolled18-100 YearsNCI Combined
001730-CPhase II Trial of Neoadjuvant Chemotherapy (NAC) Alone or in Combination with Immunotherapy Vaccine PRGN-2009 in Subjects with Newly Diagnosed HPV-Associated Oropharyngeal (Head and Neck) CancerParticipants currently recruited/enrolled18-120 YearsNCI Combined
001695-CA Phase 1/2, Open-label Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of SNS-101 (anti-VISTA) as Monotherapy and in Combination with Cemiplimab in Patients with Advanced Solid TumorsRecruitment has not started18-120 YearsNCI Combined
001658-IAdoptive T Lymphocyte Administration for Chronic Norovirus Treatment in Immunocompromised HostsParticipants currently recruited/enrolled3-80 YearsNIAIDImmunodeficiency
001625-HGProspective Study of the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism DisordersParticipants currently recruited/enrolled0-100 YearsNHGRIImmunodeficiency
001601-CA UGT1A1 Genotype-Directed Study of Belinostat Pharmacokinetics and ToxicityRecruitment has not started18-120 YearsNCI Combined
001578-CA Phase 1/2 Study of Tiragolumab (NSC# 827799, IND# 161266) and Atezolizumab (NSC# 783608, IND# 161266) in Patients with Relapsed or Refractory SMARCB1 or SMARCA4 Deficient TumorsParticipants currently recruited/enrolled3-100 YearsNCI Combined
001559-CA Feasibility Multicenter Phase I Study of Therapeutic Drug Monitoring-Based Atezolizumab DosingRecruitment has not started18-120 YearsNCI Combined
001556-CPhase II Trial of Enzalutamide and M9241 in PET Positive Recurrent Prostate Cancer (pprPC) without Testosterone Lowering TherapyParticipants currently recruited/enrolled18-120 YearsNCI Combined
001548-CA Phase I/II Study of CDX-1140, a CD40 Agonist, in Combination with Capecitabine and Oxaliplatin (CAPOX) and Keytruda in Subjects with Biliary Tract Carcinoma (BTC)Participants currently recruited/enrolled0-120 YearsNCI Combined
001541-CA Phase I/II Trial of Eltanexor (KPT-8602) with Inqovi (Decitabine-Cedazuridine) in High-Risk Myelodysplastic SyndromesParticipants currently recruited/enrolled18-120 YearsNCI Combined
001536-CPhase II Trial of Immunotherapeutic HPV Vaccine PRGN-2009 with Pembrolizumab before Standard Treatment in Subjects with Newly Diagnosed HPV-Associated Oropharyngeal CancerParticipants currently recruited/enrolled18-120 YearsNCI Combined
001535-CA Phase II Study of Sacituzumab Govitecan with or without Atezolizumab Immunotherapy in Rare Genitourinary Tumors (SMART) such as Small Cell, Adenocarcinoma, and Squamous Cell Bladder/Urinary Tract Cancer, Renal Medullary Carcinoma and Penile CancerRecruitment has not started18-120 YearsNCI Combined
001531-CA Phase II Study of Allogeneic Hematopoietic Stem Cell Transplantation with JSP191-Based Conditioning in Participants with GATA2 DeficiencyParticipants currently recruited/enrolled6-70 YearsNCI Immunodeficiency
001516-CPhase I Study of Aerosolized Antibiotics and Pembrolizumab in Advanced Non-Small Cell Lung CancerParticipants currently recruited/enrolled18-120 YearsNCI Combined
001511-IDetection and Characterization of Neurologic Manifestations of Inborn and Acquired Errors of ImmunityParticipants currently recruited/enrolled2-120 YearsNIAIDImmunodeficiency
001004-CA Phase 1b/2 Basket Study of ACR-368 as Monotherapy and in Combination with Gemcitabine in Adult Subjects with Platinum-Resistant Ovarian Carcinoma, Endometrial Adenocarcinoma, and Urothelial Carcinoma Based on Acrivon Oncosignature(R) StatusParticipants currently recruited/enrolled18-120 YearsNCI Combined
000977-IPhase I/II Study using Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Granulomatous Disease with an Alemtuzumab, Busulfan and TBI-based Conditioning Regimen Combined with Cytokine (IL-6, +/- IFN-gamma) AntagonistsParticipants currently recruited/enrolled4-65 YearsNIAIDCombined
000862-CHPilot Study of the Use of Functional Near-Infrared Spectroscopy (fNIRS) Combined with Diffuse Correlation Spectroscopy (DCS) in Neurocognitive Disease as Compared to Healthy Neurotypical ControlsParticipants currently recruited/enrolled0-110 YearsNICHDCombined
000809-IA Pilot Study of Fecal Microbiota Transplantation for Chronic Granulomatous Disease-Associated ColitisParticipants currently recruited/enrolled10-60 YearsNIAIDImmunodeficiency
000792-CA Pilot Trial to Evaluate Next-Generation Sequencing (NGS) Testing and Monitoring of B-Cell Recovery to Guide Management Following CAR T-cell Induced Remission in Pediatric Patients with B Lineage Acute Lymphoblastic LeukemiaParticipants currently recruited/enrolled1-25 YearsNCI Combined
000776-MAn Open Trial of Transcranial Magnetic Stimulation for Youth with Treatment-Resistant Major Depressive DisorderParticipants currently recruited/enrolled13-17 YearsNIMH Combined
000577-HGGenomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African Americans Study (GENEFORECAST): Prospective COVID-19 Natural History StudyCompleted Study; data analyses ongoing21-125 YearsNHGRICombined
000520-CPhase I/II Evaluation of a Cancer Lysate Vaccine and Montanide(R) ISA-51 VG with or without the IL-15 Super-Agonist N-803 as Adjuvant Therapy for PD-L1 Negative Non-Small Cell Lung CancerClinical hold/Recruitment or enrollment suspended18-125 YearsNCI Combined
000478-CA Phase I/II Trial of Allogeneic Reduced-Intensity, HLA-Haploidentical Bone Marrow Transplantation Followed by GVHD Prophylaxis with Cyclophosphamide, Bortezomib and Maraviroc for Hematologic Malignancies in People Living with HIV (PLWH)Clinical hold/Recruitment or enrollment suspended12-120 YearsNCI Immunodeficiency
000473-CA Randomized Phase II Study of Systemic Chemotherapy with or without HAI FUDR-Dexamethasone in Patients with Unresectable Intrahepatic CholangiocarcinomaParticipants currently recruited/enrolled18-125 YearsNCI Combined
000462-CPhase 2, Open-label, Single-arm, Window of Opportunity Study of ASP-1929 Photoimmunotherapy with Fluorescence Imaging in Patients With Operable Primary or Recurrent Head and Neck or Cutaneous Squamous Cell CarcinomaParticipants currently recruited/enrolled18-125 YearsNCI Combined
000406-AAAddictions Neuroclinical AssessmentEnrolling by Invitation18-99 YearsNIAAACombined
000404-CA Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Subjects with VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) SyndromeClinical hold/Recruitment or enrollment suspended18-75 YearsNCI Immunodeficiency
000392-IMetabolic Profiling of Immune Responses in Immune-Mediated DiseasesParticipants currently recruited/enrolled18-75 YearsNIAIDImmunodeficiency
000277-CImaging and Biopsy of People with HIV-1 Undergoing Analytic Treatment InterruptionParticipants currently recruited/enrolled18-100 YearsNCI Immunodeficiency
000272-HDefining the Genetic Etiology of Suppurative Lung Disease in Children and AdultsParticipants currently recruited/enrolled5-45 YearsNHLBIImmunodeficiency
000220-DKPhase II Trial of the Combination of Alpha-lipoic Acid and Mirabegron in Women and in Men with ObesityRecruitment has not started18-65 YearsNIDDKCombined
000096-CA Phase II study of Immunotherapy Combination: Irradiated PD-L1 CAR-NK cells plus Pembrolizumab plus N-803 for Subjects with Recurrent/Metastatic Gastric or Head and Neck CancerParticipants currently recruited/enrolled18-120 YearsNCI Combined
21-C-0026A Phase I/II Study of Abemaciclib in Patients with HIV-associated and HIV-negative Kaposi SarcomaParticipants currently recruited/enrolled18-125 YearsNCI Immunodeficiency
20-I-0084Sample Collection for Systems Evaluation of Patients with Unknown or Incompletely Characterized Immune DefectsParticipants currently recruited/enrolled2-120 YearsNIAIDImmunodeficiency
20-I-0037Matched Related and Unrelated Donor Stem Cell Transplantation for Severe Combined Immune Deficiency (SCID): Busulfan-based Conditioning with h-ATG, Radiation, and SirolimusEnrolling by Invitation3-40 YearsNIAIDCombined
20-C-0167Close Assessment and Testing for Chronic Graft-vs-Host Disease (CATCH Study)Participants currently recruited/enrolled18-125 YearsNCI Immunodeficiency
20-C-0155Phase I/II Trial Investigating the Safety, Tolerability, Pharmacokinetics, Immune and Clinical Activity of SX-682 in Combination with BinTrafusp Alfa (M7824 or TGF-beta "Trap"/PD-L1) with CV301 TRICOM in Advanced Solid Tumors (STAT)Completed Study; data analyses ongoing18-120 YearsNCI Combined
20-C-0104Phase I/II Trial of HPV Vaccine PRGN-2009 Alone or in Combination with Anti-PD-L1/TGF-Beta Trap (M7824) in Subjects with HPV Positive CancersNo longer recruiting/follow-up only18-120 YearsNCI Combined
20-C-0070A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Patients with Inborn Errors of ImmunityParticipants currently recruited/enrolled4-69 YearsNCI Immunodeficiency
20-C-0027A Phase I Clinical Trial of Selinexor (KPT-330) in Combination with Temozolomide and Radiation Therapy in Patients with Newly Diagnosed GlioblastomaNo longer recruiting/follow-up only18-125 YearsNCI Combined
20-C-0013Phase I/II Trial of PLX038 (PEGylated SN38) and Rucaparib in Solid Tumors and Small Cell CancersNo longer recruiting/follow-up only18-125 YearsNCI Combined
20-C-0011Phase 1 Study of Recombinant Human IL-15 (rhIL-15) and Mogamulizumab for Patients with Refractory or Relapsed Adult T-Cell Leukemia and Mycosis Fungoides/Sezary SyndromeCompleted Study; data analyses ongoing18-125 YearsNCI Immunodeficiency
20-C-0009Randomized Phase II Trial of Topotecan Plus M6620 (VX-970) vs. Topotecan Alone in Patients with Relapsed Small-Cell Lung CancerNo longer recruiting/follow-up only18-125 YearsNCI Combined
19-I-0069Phase I Open-Label Study of Safety and Immunogenicity of AD4-HIV Envelope Vaccine Vectors in Healthy VolunteersParticipants currently recruited/enrolled18-65 YearsNIAIDImmunodeficiency
19-C-0128A Phase I Study of Mesothelin-Targeted Immunotoxin LMB-100 in Combination with Tofacitinib in Persons with Previously Treated Pancreatic Adenocarcinoma, Cholangiocarcinoma and other Mesothelin Expressing Solid TumorsCompleted Study; data analyses ongoing18-125 YearsNCI Combined
19-C-0094A Phase II Study of Combined Treatment of Durvalumab, Bevacizumab, Tremelimumab and Transarterial Chemoembolization (TACE) in Subjects with Hepatocellular Carcinoma (HCC) or Biliary Tract Carcinoma (BTC)Participants currently recruited/enrolled18-125 YearsNCI Combined
19-C-0062A Phase II Study of Neoadjuvant Androgen Deprivation Therapy Combined with Enzalutamide and Abiraterone Using Multiparametric MRI and 18F-DCFPyL-PET/CT in Newly Diagnosed Prostate CancerNo longer recruiting/follow-up only18-125 YearsNCI Combined
18-I-0128Send-In Sample Collection to Achieve Genetic and Immunologic Characterization of Primary ImmunodeficienciesParticipants currently recruited/enrolled0-99 YearsNIAIDImmunodeficiency
18-I-0030VRC 603: A Phase 1 Dose-Escalation Study of the Safety of AAV8-VRC07 (VRC-HIVAAV070-00-GT) Recombinant AAV Vector Expressing VRC07 HIV-1 Neutralizing Antibody in Antiretroviral-Treated, HIV-1 Infected Adults with Controlled ViremiaNo longer recruiting/follow-up only18-65 YearsNIAIDImmunodeficiency
18-CC-0117PET Imaging of the Dopaminergic and Serotonergic Systems in Treated HIV Positive SubjectsCompleted Study; data analyses ongoing18-70 YearsCC Immunodeficiency
18-CC-0087Impact of Weekly Administration of Rifapentine and Isoniazid on Steady State Pharmacokinetics of Tenofovir Alafenamide in Healthy VolunteersCompleted Study; data analyses ongoing18-65 YearsCC Immunodeficiency
18-CC-0013A Randomized, Double-Blind, Placebo-Controlled Study of a Single Dose of Pembrolizumab in HIV-Infected PatientsParticipants currently recruited/enrolled18-99 YearsCC Immunodeficiency
18-C-0135Phase II Trial of Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or DysregulationParticipants currently recruited/enrolled4-125 YearsNCI Immunodeficiency
18-C-0078A Phase I/II Study of Immunotherapy Combination BN-Brachyury vaccine, M7824, N-803 and Epacadostat (QuEST1)No longer recruiting/follow-up only18-120 YearsNCI Combined
17-M-0147Concurrent fMRI-guided rTMS and Cognitive Therapy for the Treatment of Major Depressive EpisodesParticipants currently recruited/enrolled18-75 YearsNIMH Combined
17-I-0122NIAID Centralized Sequencing ProtocolParticipants currently recruited/enrolled0-125 YearsNIAIDImmunodeficiency
17-I-0083Targeting Residual Activity By Precision, Biomarker-Guided Combination Therapies of Multiple Sclerosis (TRAP-MS)Participants currently recruited/enrolled18-125 YearsNIAIDCombined
17-C-0174Molecular Characterization of Viral-associated Tumors, Tumors Occurring in the Setting of HIV or Other Immune Disorders and Castleman DiseaseParticipants currently recruited/enrolled18-125 YearsNCI Immunodeficiency
17-C-0048Anti-CD30 CAR T Cells with Fully-human Binding Domains for Treating CD30-expressing Lymphomas Including Anaplastic Large Cell LymphomasCompleted Study; data analyses ongoing18-73 YearsNCI Immunodeficiency
17-C-0011Phase 1 Study of Intraperitoneal Infusion of Autologous Monocytes with Sylatron(R) (Peginterferon alfa-2b) and Actimmune(R) (Interferon gamma-1b) in Women with Recurrent or Refractory Ovarian Cancer, Fallopian Tube Cancer or Primary Peritoneal CancerCompleted Study; data analyses ongoing18-125 YearsNCI Combined
16-I-0165An open-label, non-randomized extension study to evaluate the long term safety, tolerability, efficacy and pharmacokinetics of CDZ173 (leniolisib) in patients with APDS/PASLI (Activated phosphoinositide 3-kinase delta syndrome/p110 delta-activating mutatNo longer recruiting/follow-up only12-75 YearsNIAIDImmunodeficiency
16-CC-0049A Phase II Study Using LC Bead LUMI Radio-Opaque Embolic Beads to Detect and Characterize the Vascularity of Hepatic Tumors During Treatment with Transarterial Embolization (TAE) Alone or Combined with Thermal AblationCompleted Study; data analyses ongoing18-100 YearsCC Combined
16-C-0171Phase I/II Study of Lenalidomide Combined with Modified DA-EPOCH and Rituximab (EPOCH-R2) in Primary Effusion Lymphoma or KSHV-Associated Large Cell LymphomaNo longer recruiting/follow-up only18-125 YearsNCI Combined
16-C-0135A Pilot Study of Combined Immune Checkpoint Inhibition in combination with Ablative Therapies in Subjects with Hepatocellular Carcinoma (HCC) or Biliary Tract Carcinomas (BTC)Completed Study; data analyses ongoing18-125 YearsNCI Combined
16-C-0107A Phase I/II Trial of EP0057, a Nanoparticle Camptothecin with Olaparib in Patients with Relapsed/Refractory Small Cell Lung, Bladder and Prostate CancersParticipants currently recruited/enrolled18-125 YearsNCI Combined
16-C-0087Phase I Study of Veliparib (ABT-888), an Oral PARP Inhibitor, and VX-970, an ATR Inhibitor in Combination with Cisplatin in Patients with Refractory Solid TumorsCompleted Study; data analyses ongoing18-125 YearsNCI Combined
16-C-0003Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary ImmunodeficienciesParticipants currently recruited/enrolled4-75 YearsNCI Immunodeficiency
15-H-0172A Pilot Phase II Study Using Ibrutinib and Short-Course Fludarabine in Previously Untreated Patients with Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)No longer recruiting/follow-up only18-125 YearsNHLBICombined
15-DK-0079Observational Study of Hepatitis B Virus (HBV) in Patients Coinfected with Human Immunodeficiency Virus (HIV)Completed Study; data analyses ongoing18-125 YearsNIDDKImmunodeficiency
14-I-0146The Pathogenesis and Genetics of Disseminated or Refractory CoccidioidomycosisParticipants currently recruited/enrolled2-100 YearsNIAIDImmunodeficiency
14-I-0020Hematopoietic Stem Cell Mobilization in Idiopathic CD4 Lymphocytopenia Patients and Healthy Controls for the Study of T Cell Maturation and Trafficking in Murine ModelsParticipants currently recruited/enrolled18-65 YearsNIAIDImmunodeficiency
14-I-0009Characterization and Management of Patients with HIV-1 Infection Who Experience Virologic Failure Despite Combination Antiretroviral TherapyCompleted Study; data analyses ongoing18-100 YearsNIAIDImmunodeficiency
14-HG-0055Study on Moebius Syndrome and Other Congenital Facial Weakness DisordersCompleted Study; data analyses ongoing2-80 YearsNHGRICombined
14-C-0157Phase 1 Study of Ibrutinib and Immuno-Chemotherapy Using Temozolomide, Etoposide, Doxil, Dexamethasone, Ibrutinib, Rituximab (TEDDI-R) in Primary CNS LymphomaParticipants currently recruited/enrolled18-125 YearsNCI Combined
13-N-0149An Evaluation of HIV-associated Neurocognitive Disorders (HAND) in Virologically Controlled PatientsParticipants currently recruited/enrolled18-110 YearsNINDSImmunodeficiency
13-N-0017Natural History Study of Progressive Multifocal Leukoencephalopathy (PML)Participants currently recruited/enrolled2-120 YearsNINDSImmunodeficiency
13-I-0062A Double Blind Randomized Placebo Controlled Study Examining the Effects of a Non-Absorbable (Rifaximin) Antibiotic on the Chronic Immune Activation Observed In HIV-infected SubjectsCompleted Study; data analyses ongoing18-65 YearsNIAIDImmunodeficiency
13-C-0132Allogeneic Hematopoietic Stem Cell Transplant for Patients with Mutations in GATA2 or the MonoMAC SyndromeParticipants currently recruited/enrolled8-70 YearsNCI Immunodeficiency
12-M-0128TMS Investigations of the Human Visual SystemParticipants currently recruited/enrolled18-50 YearsNIMH Combined
12-C-0081Phase I/II Study of Cediranib and Olaparib in Combination for Treatment of Recurrent Papillary-Serous Ovarian, Fallopian Tube, or Peritoneal Cancer or for Treatment of Recurrent Triple-Negative Breast CancerNo longer recruiting/follow-up only18-125 YearsNCI Combined
11-I-0057Effect of Interferon Alpha 2b Intensification on HIV-1 Residual Viremia in Individuals Suppressed on Antiretroviral TherapyCompleted Study; data analyses ongoing18-65 YearsNIAIDImmunodeficiency
11-CC-0152The Natural History of Liver Disease in a Cohort of Participants with Hepatitis B and/or Hepatitis C with or without HIV InfectionCompleted Study; data analyses ongoing18-99 YearsCC Immunodeficiency
11-C-0247A Randomized Phase II Study of Tecemotide in Combination with Standard Androgen Deprivation Therapy and Radiation Therapy for untreated, intermediate and High Risk Prostate Cancer PatientsCompleted Study; data analyses ongoing18-100 YearsNCI Combined
11-C-0140A Phase I Study of Gemcitabine, Carboplatin and Lenalidomide (GCL) for Treatment of Patients with Advanced/Metastatic Urothelial Carcinoma (UC) and Other Solid TumorsCompleted Study; data analyses ongoing18-125 YearsNCI Combined
10-I-0014The Natural History of Severe Viral Infections and Characterization of Immune DefectsParticipants currently recruited/enrolled2-125 YearsNIAIDImmunodeficiency
10-C-0201Apheresis and CD34+ Selection of Mobilized Peripheral Blood CD34+ Cells from Patients with DOCK8 Deficiency, LAD-1, and GATA2 DeficiencyParticipants currently recruited/enrolled18-40 YearsNCI Immunodeficiency
10-C-0174Related and Unrelated Donor Hematopoietic Stem Cell Transplant for DOCK8 DeficiencyParticipants currently recruited/enrolled4-120 YearsNCI Immunodeficiency
10-C-0025Randomized Phase II Trial of Rituximab with Either Pentostatin or Bendamustine for Multiply Relapsed or Refractory Hairy Cell LeukemiaNo longer recruiting/follow-up only18-125 YearsNCI Combined
09-I-0200A Phase I Study of MozobilTM in the Treatment of Patients with WHIMSParticipants currently recruited/enrolled18-75 YearsNIAIDImmunodeficiency
09-I-0126Pathogenesis and Genetic Basis of Physical Induced Urticarial SyndromesCompleted Study; data analyses ongoing2-90 YearsNIAIDImmunodeficiency
09-I-0102Etiology, Pathogenesis, and Natural History of Idiopathic CD4+ LymphocytopeniaParticipants currently recruited/enrolled18-125 YearsNIAIDImmunodeficiency
09-I-0086Screening Protocol for Genetic Diseases of Allergic InflammationCompleted Study; data analyses ongoing0-99 YearsNIAIDImmunodeficiency
09-I-0013Biomarkers of Inflammation, Coagulation, and Endothelial Function in HIV-Infected AdultsCompleted Study; data analyses ongoing18-100 YearsNIAIDCombined
09-H-0172Natural History of BronchiectasisParticipants currently recruited/enrolled5-100 YearsNHLBIImmunodeficiency
09-C-0024A Phase I Study of Quadrivalent Human Papilloma Virus (HPV) (Types 6, 11, 16, 18) Recombinant Vaccine in HIV-Infected and HIV-Negative Pre-Adolescents, Adolescents and Young AdultsCompleted Study; data analyses ongoing12-26 YearsNCI Immunodeficiency
08-HG-0059Studies of Skin Microflora in Healthy Individuals and Atopic Dermatitis PatientsParticipants currently recruited/enrolled2-100 YearsNHGRIImmunodeficiency
06-I-0015Screening Protocol for Genetic Diseases of Lymphocyte Homeostasis and Programmed Cell DeathParticipants currently recruited/enrolled0-100 YearsNIAIDImmunodeficiency
04-E-0053Personalized Environment and Genes StudyParticipants currently recruited/enrolled18-120 YearsNIEHSCombined
04-C-0281Natural History Study of Clinical and Biological Factors Determining Outcomes in Chronic Graft-Versus-Host DiseaseParticipants currently recruited/enrolled1-125 YearsNCI Immunodeficiency
04-C-0275Targeted Oncolytic Virotherapy and Natural History Study of KSHV-Associated Multicentric Castleman's Disease with Laboratory and Clinical Correlates of Disease ActivityNo longer recruiting/follow-up only18-125 YearsNCI Combined
03-H-0170Nonmyeloablative Allogeneic Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Severe Congenital Anemias Including Sickle Cell Disease (SCD) and B-ThalassemiaNo longer recruiting/follow-up only2-80 YearsNHLBICombined
01-C-0129Eligibility Screening for the NIH Intramural Research Program Clinical ProtocolsEnrolling by Invitation0-125 YearsNCI Immunodeficiency
01-C-0030Short-Course EPOCH - Rituximab in Untreated CD-20+ HIV-Associated LymphomasCompleted Study; data analyses ongoing18-125 YearsNCI Immunodeficiency
00-HG-0209Molecular and Clinical Studies of Primary Immunodeficiency DiseasesNo longer recruiting/follow-up only3-125 YearsNHGRIImmunodeficiency
00-C-0074Evaluation of Late Effects and Natural History of Disease in Patients Treated with RadiotherapyParticipants currently recruited/enrolled18-125 YearsNCI Combined
95-I-0066Genetic Analysis of Immune DisordersParticipants currently recruited/enrolled0-101 YearsNIAIDImmunodeficiency
94-DK-0133Genetic Markers for Focal Segmental GlomerulosclerosisCompleted Study; data analyses ongoing1-125 YearsNIDDKImmunodeficiency
92-I-0125A Study of Viral Burden in Peripheral Blood Versus Lymphoid and Bone Marrow Tissue in HIV-Infected IndividualsParticipants currently recruited/enrolled18-125 YearsNIAIDImmunodeficiency
89-N-0045Evaluation of Progression in Multiple Sclerosis by Magnetic Resonance Imaging (MRI)Participants currently recruited/enrolled18-120 YearsNINDSCombined
89-I-0158Studies of Immune Regulation in Patients with Common Variable Immunodeficiency and Related Humoral Immunodeficiency SyndromesParticipants currently recruited/enrolled2-120 YearsNIAIDImmunodeficiency
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