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95 Studies found from all possible combinations of your search terms. Select a protocol that you wish to review.
Protocol Number
Title
Protocol Status
Min-Max Age
Institute
Keywords
20-EI-0163
Oral Metformin for Treatment of ABCA4 Retinopathy
Participants currently recruited/enrolled
12-100 Years
NEI
Retinal Degeneration
20-EI-0052
A Phase I/IIa Trial for Autologous Transplantation of Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium for Geographic Atrophy Associated with Age-Related Macular Degeneration
Participants currently recruited/enrolled
55-125 Years
NEI
Retinal Degeneration
20-EI-0026
An Observational Cross-Sectional Study of Virtual Reality Mobility Assessment of Functional Vision in Retinal Disease
Participants currently recruited/enrolled
5-125 Years
NEI
Retinal Degeneration
18-EI-0068
An Investigation of Vitamin A Palmitate Supplementation in Patients with Reticular Pseudodrusen (RPD) and Delayed Dark Adaptation
Participants currently recruited/enrolled
50-125 Years
NEI
Retinal Degeneration
18-EI-0067
An Investigation of Vitamin A Palmitate Supplementation in Patients with Age-Related Macular Degeneration (and without reticular pseudodrusen) and Delayed Dark Adaptation
Participants currently recruited/enrolled
50-125 Years
NEI
Retinal Degeneration
16-EI-0024
Rod and Cone Mediated Function in Retinal Disease
Participants currently recruited/enrolled
5-100 Years
NEI
Retinal Degeneration
14-EI-0171
The Focal Electro-Oculogram in Macular Disease
Completed Study; data analyses ongoing
10-100 Years
NEI
Retinal Degeneration
12-EI-0203
Natural History of ABCA4-Related Retinopathies
No longer recruiting/follow-up only
12-100 Years
NEI
Retinal Degeneration
12-EI-0042
NEI Intramural Biorepository for Retinal Diseases
Participants currently recruited/enrolled
2-125 Years
NEI
Retinal Degeneration
11-EI-0245
Generation of Induced Pluripotent Stem (iPS) Cell Lines from Somatic Cells of Participants with Eye Diseases and from Somatic Cells of Matched Controls
Participants currently recruited/enrolled
0-120 Years
NEI
Retinal Degeneration
06-EI-0236
National Ophthalmic Genotyping and Phenotyping Network Stage 1 - Creation of DNA Repository for Inherited Ophthalmic Diseases
No longer recruiting/follow-up only
2-125 Years
NEI
Retinal Degeneration
001678-AT
Microneurographic Assessment of Peripheral Nerves in Healthy Volunteers and Individuals with Sensory Dysfunction Caused by Inherited Mutations in the PIEZO2 Gene
Recruitment has not started
18-100 Years
NCCIH
Peripheral
001642-N
ALLFTD: ARTFL-LEFFTDS Longitudinal Frontotemporal Lobar Degeneration
Participants currently recruited/enrolled
18-99 Years
NINDS
Degeneration
001549-C
Phase II Evaluation of Decitabine/Cedazuridine (INQOVI), an Oral DNA Demethylating Agent in Subjects with BAP1 Cancer Predisposition Syndrome and Subclinical, Early-Stage Mesothelioma
Recruitment has not started
18-120 Years
NCI
Peripheral
001544-C
Phase I/II Evaluation of a Cancer Lysate Vaccine and Montanide(R) ISA-51 VG with Entinostat and Nivolumab as Adjuvant Therapy following Chemoradiation Therapy with or without Surgery for Locally Advanced Esophageal Cancer
Recruitment has not started
18-120 Years
NCI
Peripheral
000908-DK
Peripheral Blood and Urine Immune Cell Phenotyping in Membranous Nephropathy using FACS and Single Cell RNA-seq
Participants currently recruited/enrolled
18-125 Years
NIDDK
Peripheral
000633-C
Phase 1/2 Study of VIP152, Venetoclax, and Prednisone (VVIP) in Relapsed/Refractory Lymphoid Malignancies
Participants currently recruited/enrolled
18-125 Years
NCI
Peripheral
000625-N
Investigational use of Neuromuscular Ultrasound
Participants currently recruited/enrolled
18-110 Years
NINDS
Peripheral
000613-C
Phase I/II Trial to Determine the Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination with Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis after Reduced Intensity Conditioning and Peripheral Blood St
Participants currently recruited/enrolled
12-125 Years
NCI
Peripheral
000585-CH
An Open-label Safety, Pharmacokinetic, and Efficacy Study of Miglustat for the Treatment of CLN3 Disease in Patients 17 Years of Age and Older
Participants currently recruited/enrolled
17-125 Years
NICHD
Retinal
000473-C
A Randomized Phase II Study of Systemic Chemotherapy with or without HAI FUDR-Dexamethasone in Patients with Unresectable Intrahepatic Cholangiocarcinoma
Participants currently recruited/enrolled
18-125 Years
NCI
Peripheral
000413-H
Natural History study of CADASIL
Participants currently recruited/enrolled
18-100 Years
NHLBI
Degeneration
000317-C
A Phase II, Open-Label Trial of PT-112 in Subjects with Thymoma and Thymic Carcinoma
Participants currently recruited/enrolled
18-125 Years
NCI
Peripheral
000187-EI
Adaptive Optics Imaging of Outer Retinal Diseases
Participants currently recruited/enrolled
21-125 Years
NEI
Retinal
21-C-0015
Phase II Trial Evaluating the Association of Peripheral Blood Immunologic Response to Therapeutic Response to Adjuvant Treatment with Immune Checkpoint Inhibition (ICI) in Patients with Newly Diagnosed Glioblastoma or Gliosarcoma
Participants currently recruited/enrolled
18-125 Years
NCI
Peripheral
20-C-0127
A Phase 1 Study of Romidepsin, CC-486 (5-azacitidine), dexamethasone, and lenalidomide (RAdR) for relapsed/refractory T-cell malignancies
Participants currently recruited/enrolled
18-125 Years
NCI
Peripheral
20-C-0121
Rapid Analysis and Response Evaluation of Combination Anti-Neoplastic Agents in Rare Tumors (RARE CANCER) Trial: RARE 1 Nilotinib and Paclitaxel
Participants currently recruited/enrolled
18-125 Years
NCI
Peripheral
20-C-0041
Protocol for a Research Database for Hematopoietic Cell Transplantation, Other Cellular Therapies and Marrow Toxic Injuries
Enrolling by Invitation
1-125 Years
NCI
Peripheral
20-C-0023
First-in-Human Phase I Trial to Investigate the Safety, Tolerability, Pharmacokinetics, Biological and Clinical Activity of Metarrestin (ML-246) in Subjects with Metastatic Solid Tumors
Participants currently recruited/enrolled
12-125 Years
NCI
Peripheral
19-I-0080
Haploidentical Transplant for Patients with Chronic Granulomatous Disease (CGD) using Alemtuzumab, Busulfan and TBI with Post-Transplant Cyclophosphamide
Participants currently recruited/enrolled
4-65 Years
NIAID
Peripheral
19-H-0118
Repeat Peripheral Blood Stem Cell Transplantation for Patients with Sickle Cell Disease or Beta-Thalassemia and Falling Donor Myeloid Chimerism Levels
Participants currently recruited/enrolled
2-80 Years
NHLBI
Peripheral
19-C-0085
Phase II Trial of Allogeneic Hematopoietic Cell Transplantation for Peripheral T cell Lymphoma
Clinical hold/Recruitment or enrollment suspended
12-125 Years
NCI
Peripheral
19-C-0076
A Phase 1 Study of Interleukin-15 in Combination with Avelumab (Bavencio) in Relapsed/Refractory Mature T-cell Malignancies
Completed Study; data analyses ongoing
18-125 Years
NCI
Peripheral
19-C-0061
A Phase 2 Trial of the MEK Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in Combination with the mTOR Inhibitor Sirolimus for Patients with Unresectable or Metastatic Malignant Peripheral Nerve Sheath Tumors
Participants currently recruited/enrolled
12-125 Years
NCI
Peripheral
19-C-0046
Long-Term Follow-up Protocol for Subjects Treated with Gene-Modified T cells.
No longer recruiting/follow-up only
18-125 Years
NCI
Peripheral
19-C-0017
A Phase I/II Study Administering Peripheral Blood Lymphocytes Transduced with a Murine T-Cell Receptor Recognizing the G12D Variant of Mutated RAS in HLA-A*11:01 Patients
Participants currently recruited/enrolled
18-72 Years
NCI
Peripheral
19-C-0016
Natural History and Biospecimen Acquisition Study for Children and Adults with Rare Solid Tumors
Participants currently recruited/enrolled
0-125 Years
NCI
Peripheral
18-H-0090
Haplo-identical Transplantation for Severe Aplastic Anemia, Hypo-plastic MDS and PNH using Peripheral Blood Stem Cells and post-transplant Cyclophosphamide for GVHD prophylaxis
Participants currently recruited/enrolled
4-75 Years
NHLBI
Peripheral
17-H-0124
Peripheral Blood Stem Cell Collection for Sickle Cell Disease (SCD) Patients Using Plerixafor
Completed Study; data analyses ongoing
18-125 Years
NHLBI
Peripheral
17-H-0069
Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease
No longer recruiting/follow-up only
2-100 Years
NHLBI
Peripheral
17-EI-0112
A Long-term Follow-up Study of Participants Enrolled in 11-EI-0147: Longitudinal Investigation of Dark Adaptation in Participants with Age-Related Macular Degeneration (DA_AMD)
Participants currently recruited/enrolled
50-125 Years
NEI
Degeneration
17-EI-0071
AMD Ryan Initiative Study
Completed Study; data analyses ongoing
55-125 Years
NEI
Degeneration
17-EI-0008
The Natural History of Geographic Atrophy Associated with Age-Related Macular Degeneration
Participants currently recruited/enrolled
55-120 Years
NEI
Degeneration
17-C-0113
A Phase I/II Study Administering Peripheral Blood Lymphocytes Transduced with a Murine T-Cell Receptor Recognizing the G12V Variant of Mutated RAS in HLA-A*11:01 Patients
Participants currently recruited/enrolled
18-72 Years
NCI
Peripheral
17-C-0048
Anti-CD30 CAR T Cells with Fully-human Binding Domains for Treating CD30-expressing Lymphomas Including Anaplastic Large Cell Lymphomas
Completed Study; data analyses ongoing
18-73 Years
NCI
Peripheral
16-I-0032
High Dose Peripheral Blood Stem Cell Transplantation with Post Transplant Cyclophosphamide for Patients with Chronic Granulomatous Disease
No longer recruiting/follow-up only
4-65 Years
NIAID
Peripheral
16-H-0132
CADASIL Disease Discovery
Completed Study; data analyses ongoing
18-100 Years
NHLBI
Degeneration
16-C-0138
Collection of Peripheral Blood Mononuclear Cells (PBMCs) from Healthy Subjects for the Expansion of T Cells for Adoptive Cell Therapy
Participants currently recruited/enrolled
18-120 Years
NCI
Peripheral
16-C-0135
A Pilot Study of Combined Immune Checkpoint Inhibition in combination with Ablative Therapies in Subjects with Hepatocellular Carcinoma (HCC) or Biliary Tract Carcinomas (BTC)
Completed Study; data analyses ongoing
18-125 Years
NCI
Peripheral
16-C-0131
A Phase I/II Study Administering Peripheral Blood Lymphocytes Transduced with a CD70-Binding Chimeric Antigen Receptor to Patients with CD70-Expressing Cancers
Participants currently recruited/enrolled
18-72 Years
NCI
Peripheral
15-H-0016
A Phase II Study Using ACP-196 in Patients with Relapsed/Refractory and Treatment Naive Deletion 17p CLL/SLL: Pharmacodynamic Assessment of BTK Inhibition and Anti-Tumor Response.
No longer recruiting/follow-up only
18-125 Years
NHLBI
Peripheral
15-EI-0202
Evaluation of Oral Minocycline in the Treatment of Geographic Atrophy Associated with Age-Related Macular Degeneration
Completed Study; data analyses ongoing
55-100 Years
NEI
Degeneration
15-EI-0038
A Phase I/IIa Study of RS1 Ocular Gene Transfer for X-linked Retinoschisis
No longer recruiting/follow-up only
18-125 Years
NEI
Retinal
15-EI-0020
Adaptive Optics Retinal Imaging
Participants currently recruited/enrolled
12-125 Years
NEI
Retinal
15-C-0078
Safety and Feasibility of Stem Cell Gene Transfer Following R-EPOCH for Non-Hodgkin Lymphoma in AIDS Patients Using Peripheral Blood Stem/Progenitor Cells Treated with a Lentivirus Vector-Encoding Multiple Anti-HIV RNAs
No longer recruiting/follow-up only
18-65 Years
NCI
Peripheral
15-AR-0060
The Role of PPAR-gamma Agonists in immunomodulation and Vascular Prevention in SLE (PPAR-SLE)
Completed Study; data analyses ongoing
18-99 Years
NIAMS
Peripheral
14-I-0020
Hematopoietic Stem Cell Mobilization in Idiopathic CD4 Lymphocytopenia Patients and Healthy Controls for the Study of T Cell Maturation and Trafficking in Murine Models
Participants currently recruited/enrolled
18-65 Years
NIAID
Peripheral
14-HG-0048
Genomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African-Americans Study (GENE-FORECAST)
No longer recruiting/follow-up only
21-125 Years
NHGRI
Peripheral
14-H-0077
Nonmyeloablative Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease and Beta-Thalassemia in Individuals with Higher Risk of Transplant Failure
Participants currently recruited/enrolled
4-80 Years
NHLBI
Peripheral
14-C-0163
Transformation of Plexiform Neurofibromas to Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis Type 1: Clinical, Histopathologic, and Genomic Analysis
Completed Study; data analyses ongoing
10-125 Years
NCI
Peripheral
13-N-0188
Natural History and Biomarkers of C9ORF72 Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
Completed Study; data analyses ongoing
18-125 Years
NINDS
Degeneration
13-EI-0049
Pathogenesis and Genetics of Microphthalmia, Anophthalmia and Uveal Coloboma ( MAC)
Participants currently recruited/enrolled
1-125 Years
NEI
Retinal
13-C-0132
Allogeneic Hematopoietic Stem Cell Transplant for Patients with Mutations in GATA2 or the MonoMAC Syndrome
Participants currently recruited/enrolled
8-70 Years
NCI
Peripheral
11-I-0007
Lentiviral Gene Transfer for Treatment of Children Older Than 2 Years of Age with X-Linked Severe Combined Immunodeficiency
Clinical hold/Recruitment or enrollment suspended
2-40 Years
NIAID
Peripheral
11-EI-0264
A Pilot Study for the Evaluation of Minocycline as a Microglia Inhibitor in the Treatment of Central Retinal Vein Occlusions
Completed Study; data analyses ongoing
18-125 Years
NEI
Retinal
11-EI-0263
A Pilot Study for the Evaluation of Minocycline as a Microglia Inhibitor in the Treatment of Branch Retinal Vein Occlusions
Completed Study; data analyses ongoing
18-125 Years
NEI
Retinal
11-EI-0147
Longitudinal Investigation of Dark Adaptation in Participants with Age-Related Macular Degeneration
Participants currently recruited/enrolled
50-125 Years
NEI
Degeneration
10-EI-0140
Genotype - phenotype Study of Patients with Plaquenil-induced Retinal Toxicity
Participants currently recruited/enrolled
18-125 Years
NEI
Retinal
10-DK-N091
Molecular and Clinical Profile of Diabetes Mellitus and its Complications
Participants currently recruited/enrolled
18-125 Years
NIDDK
Retinal
10-C-0201
Apheresis and CD34+ Selection of Mobilized Peripheral Blood CD34+ Cells from Patients with DOCK8 Deficiency, LAD-1, and GATA2 Deficiency
Participants currently recruited/enrolled
18-40 Years
NCI
Peripheral
09-H-0225
Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Severe Congenital Anemias Including Sickle Cell Disease and Beta-Thalassemia
No longer recruiting/follow-up only
2-100 Years
NHLBI
Peripheral
08-N-0044
A Prospective Natural History Study of Patients with Neurofibromatosis Type 2 (NF2).
Participants currently recruited/enrolled
8-75 Years
NINDS
Peripheral
08-H-0046
Co-Infusion of Umbilical Cord Blood and Haploidentical CD34+ Cells Following Nonmyeloablative Conditioning as Treatment for Severe Aplastic Anemia and MDS Associated with Severe Neutropenia Refractory to Immunosuppressive Therapy
Completed Study; data analyses ongoing
4-75 Years
NHLBI
Peripheral
08-EI-0102
Screening Protocol for the Evaluation and Diagnosis of Potential Research Participants
Participants currently recruited/enrolled
2-100 Years
NEI
Retinal
08-EI-0043
Age-Related Eye Disease Study (AREDS) and AREDS2 Follow-Up
No longer recruiting/follow-up only
50-100 Years
NEI
Degeneration
08-C-0130
A Phase II Trial of Peginterferon alfa-2b (PEG-Intron) for Neurofibromatosis Type 1 Related Unresectable, Symptomatic or Life-Threatening Plexiform Neurofibromas
Completed Study; data analyses ongoing
0-21 Years
NCI
Peripheral
08-C-0079
Natural History Study and Longitudinal Assessment of Children, Adolescents, and Adults with Neurofibromatosis Type 1
No longer recruiting/follow-up only
0-125 Years
NCI
Peripheral
07-N-0122
Modulation of Motor Function by Stimulation of the Central and Peripheral Nervous System
Completed Study; data analyses ongoing
18-125 Years
NINDS
Peripheral
05-H-0130
Long-Term Evaluation and Follow Up Care of Patients Treated with Allogeneic Stem Cell Transplants
Participants currently recruited/enrolled
7-80 Years
NHLBI
Peripheral
04-C-0238
A Phase 2 Study of 17-Allylamino-17-Demethoxygeldanamycin in Patients with Von Hippel Lindau Disease and Renal Tumors
Completed Study; data analyses ongoing
18-125 Years
NCI
Retinal
03-H-0170
Nonmyeloablative Allogeneic Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Severe Congenital Anemias Including Sickle Cell Disease (SCD) and B-Thalassemia
No longer recruiting/follow-up only
2-80 Years
NHLBI
Peripheral
03-EI-0033
X-Linked Juvenile Retinoschisis - Clinical and Molecular Studies
Participants currently recruited/enrolled
0-125 Years
NEI
Degeneration
02-I-0286
Efficacy of Tyrosine Kinase Inhibition in Reducing Eosinophilia in Patients with Myeloid and/or Steroid-Refractory Hypereosinophilic Syndrome
Participants currently recruited/enrolled
2-125 Years
NIAID
Peripheral
02-H-0250
A Phase I/II Study of HLA-matched Mobilized Peripheral Blood Hematopoietic Stem Cell Transplantation for Advanced Mycosis Fungoides/Sezary Syndrome Using Nonmyeloablative Conditioning with Campath-1H
Completed Study; data analyses ongoing
18-100 Years
NHLBI
Peripheral
02-C-0064
Collection of Peripheral Blood and/or Urine From Patients Undergoing Radiation Therapy
Enrolling by Invitation
18-125 Years
NCI
Peripheral
00-N-0043
Clinical and Molecular Manifestations of Inherited Neurological Disorders
Participants currently recruited/enrolled
2-120 Years
NINDS
Peripheral
99-H-0050
Non-Myeloablative Allogeneic Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Hematologic Malignancies in High Risk Patients and in Patients with Debilitating Hematologic Diseases
Completed Study; data analyses ongoing
2-80 Years
NHLBI
Peripheral
96-H-0049
Use of Granulocyte Colony Stimulating Factor (G-CSF) Mobilized Leukapheresis Collections from Healthy Volunteers to Develop Improved Methods of Stem Cell and Lymphocyte Selection for Allogeneic Transplantation
Participants currently recruited/enrolled
18-60 Years
NHLBI
Peripheral
94-I-0079
Eosinophil Activation and Function in Parasitic Infections and Other Conditions with Increased Tissue or Peripheral Blood Eosinophilia in Humans
Participants currently recruited/enrolled
1-100 Years
NIAID
Peripheral
94-I-0073
Recruitment and Apheresis Collection of Peripheral Blood Hematopoietic Stem Cells, Mononuclear Cells and Granulocytes
Participants currently recruited/enrolled
18-70 Years
NIAID
Peripheral
94-HG-0105
An Exploratory Study of the Genetics, Pathophysiology, and Natural History of Autoinflammatory Diseases
Participants currently recruited/enrolled
0-115 Years
NHGRI
Retinal
93-I-0063
Study of the Immunopathogenesis, Natural History, and Genetics of Autoimmune Lymphoproliferative Syndrome (ALPS) Associated with an Expansion of CD4-8-/TCR alpha/beta+ T Cells
Participants currently recruited/enrolled
0-99 Years
NIAID
Peripheral
92-I-0125
A Study of Viral Burden in Peripheral Blood Versus Lymphoid and Bone Marrow Tissue in HIV-Infected Individuals
Participants currently recruited/enrolled
18-125 Years
NIAID
Peripheral
91-I-0140
Studies of the Pathogenesis of HIV Infection in Human Peripheral Blood Cells and/or Body Fluids in HIV-Infected and HIV-Uninfected Volunteers
Participants currently recruited/enrolled
18-125 Years
NIAID
Peripheral
91-AR-0196
Studies on the Natural History and Pathogenesis of Polymyositis, Dermatomyositis, and Related Diseases
No longer recruiting/follow-up only
16-125 Years
NIAMS
Degeneration