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42 Studies found from all possible combinations of your search terms. Select a protocol that you wish to review.

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Protocol Number Title Protocol Status Min-Max Age Institute Keywords
000479-HObservational Study to Deeply Phenotype Major Organs in Sickle Cell Disease After Curative TherapiesParticipants currently recruited/enrolled18-100 YearsNHLBIFetal Hemoglobin
08-DK-0004High Sensitivity Screening of Compound Libraries to Discover a Drug for the Treatment of Sickle Cell DiseaseParticipants currently recruited/enrolled18-100 YearsNIDDKHemoglobin Trait
01-H-0122Collection and Storage of Umbilical Cord Hematopoietic Stem Cells for Sickle Cell Disease TherapyParticipants currently recruited/enrolled18-45 YearsNHLBIHemoglobin Trait
001883-HDetermination of Red Cell Survival in Sickle Cell Disease and Other Hemoglobinopathies Using Biotin LabelingParticipants currently recruited/enrolled18-100 YearsNHLBIHemoglobin
001619-HA Phase I Study to Evaluate the Safety and Tolerability of Escalating Doses of Fostamatinib in Subjects with Stable Sickle Cell DiseaseRecruitment has not started18-65 YearsNHLBIHemoglobin
001528-HA Phase I/II, Intra-Patient Dose-Escalation Study of the Selective GlyT1 Inhibitor, Bitopertin for Steroid-Refractory Diamond-Blackfan Anemia.Participants currently recruited/enrolled18-100 YearsNHLBIHemoglobin
001074-CHCharacterization of Dysmorphology in Subjects with Creatine Transporter DeficiencyParticipants currently recruited/enrolled2-40 YearsNICHDTrait
001061-HObservational Study Investigating the Mechanistic Effects of Mitapivat in Subjects with Sickle Cell DiseaseEnrolling by Invitation16-80 YearsNHLBIHemoglobin
000784-NAssessing and Improving Quantitative Magnetic Resonance Imaging Metrics in Human SubjectsParticipants currently recruited/enrolled18-100 YearsNINDSQuantitative
000518-CCObservational Study of Dietary Intake and Dietary Behaviors in Adults with Sickle Cell DiseaseParticipants currently recruited/enrolled18-120 YearsCC Hemoglobin
000417-CCCharacterization of the Nociception Phenotype in Individuals with Intellectual DisabilityParticipants currently recruited/enrolled8-30 YearsCC Quantitative
000137-CHImplications of Maternal 45,X Mosaicism As A Secondary Genomic Finding Following Cell-free DNA Sequencing During Pregnancy: A Deep Phenotype StudyRecruitment has not started18-99 YearsNICHDFetal
20-H-0068Venous Thrombosis Biomarkers in Sickle Cell Disease and Sickle Cell TraitNo longer recruiting/follow-up only18-80 YearsNHLBITrait
20-H-0021Treatment of Refractory Diamond-Blackfan Anemia with EltrombopagCompleted Study; data analyses ongoing2-99 YearsNHLBIHemoglobin
19-H-0097A Pilot Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Escalating Multiple Oral Doses of AG-348 in Subjects with Stable Sickle Cell DiseaseCompleted Study; data analyses ongoing18-70 YearsNHLBIHemoglobin
18-HG-0129Reverse Phenotyping Core (RPC)Enrolling by Invitation4-120 YearsNHGRITrait
18-H-0146Genotype -Phenotype Correlation of PKLR Variants with Pyruvate Kinase, 2,3-Diphosphglycerate and ATP Activities in Red Blood Cells of Patients with Sickle Cell DiseaseParticipants currently recruited/enrolled18-80 YearsNHLBITrait
18-H-0090Haplo-identical Transplantation for Severe Aplastic Anemia, Hypo-plastic MDS and PNH using Peripheral Blood Stem Cells and post-transplant Cyclophosphamide for GVHD ProphylaxisParticipants currently recruited/enrolled4-75 YearsNHLBIHemoglobin
18-D-0114An Open Label Pilot Study of Denosumab Treatment for Fibrous DysplasiaCompleted Study; data analyses ongoing18-125 YearsNIDCRQuantitative
17-CC-0148Obtaining Samples from Human Subjects to Facilitate Basic, Translational and Clinical ResearchParticipants currently recruited/enrolled18-100 YearsCC Hemoglobin
17-C-0048Anti-CD30 CAR T Cells with Fully-human Binding Domains for Treating CD30-expressing Lymphomas Including Anaplastic Large Cell LymphomasCompleted Study; data analyses ongoing18-73 YearsNCI Hemoglobin
16-I-0065Screening for Alpha Globin DeletionsNo longer recruiting/follow-up only18-39 YearsNIAIDTrait
16-C-0138Collection of Peripheral Blood Mononuclear Cells (PBMCs) from Healthy Subjects for the Expansion of T Cells for Adoptive Cell TherapyParticipants currently recruited/enrolled18-120 YearsNCI Hemoglobin
15-I-0056Collection of Plasma from Subjects that Recovered From or Were Vaccinated To Emerging Infectious DiseasesEnrolling by Invitation18-70 YearsNIAIDQuantitative
14-DK-0060Famine from Feast: Linking Vitamin C, Red Blood Cell Fragility, and DiabetesParticipants currently recruited/enrolled18-65 YearsNIDDKHemoglobin
14-CC-0143Sleep Disturbance and Relapse in Individuals with Alcohol Dependence: An Exploratory Mixed Methods StudyCompleted Study; data analyses ongoing18-125 YearsCC Quantitative
14-AA-0181NIAAA Natural History ProtocolParticipants currently recruited/enrolled18-100 YearsNIAAATrait
11-H-0134A Pilot Study of a Thrombopoietin-Receptor Agonist (TPO-R Agonist), Eltrombopag, in Moderate Aplastic Anemia PatientsNo longer recruiting/follow-up only2-99 YearsNHLBIHemoglobin
10-H-0154Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused with a Reduced Dose of Non-Mobilized Donor T-CellsParticipants currently recruited/enrolled4-80 YearsNHLBIHemoglobin
09-C-0005Randomized Trial of Cladribine (CdA) with Simultaneous or Delayed Rituximab to Eliminate Hairy Cell Leukemia Minimal Residual DiseaseNo longer recruiting/follow-up only18-125 YearsNCI Quantitative
07-DK-0077Study of the Phenotype of Overweight and Obese AdultsParticipants currently recruited/enrolled18-100 YearsNIDDKTrait
06-M-0214PET Measurement of Regional Rates of Cerebral Protein Synthesis in Subjects with Fragile X SyndromeCompleted Study; data analyses ongoing18-24 YearsNIMH Quantitative
04-H-0161Studies of the Natural History of Sickle Cell DiseaseParticipants currently recruited/enrolled2-90 YearsNHLBIHemoglobin
03-M-0211Family Study of Affective and Anxiety Spectrum DisordersParticipants currently recruited/enrolled7-120 YearsNIMH Trait
03-DK-0257Phase II Trial of Effect of Metreleptin Therapy in Severe Insulin ResistanceNo longer recruiting/follow-up only5-80 YearsNIDDKHemoglobin
02-HG-0107Natural History of Glycosphingolipid Storage Disorders and Glycoprotein DisordersParticipants currently recruited/enrolled0-125 YearsNHGRIFetal
02-DK-N304Diabetes Prevention Program Outcomes Study (DPPOS)Participants currently recruited/enrolled25-99 YearsNIDDKHemoglobin
01-H-0088Determining the Prevalence and Prognosis of Secondary Pulmonary Hypertension in Adult Patients with Sickle Cell AnemiaCompleted Study; data analyses ongoing18-125 YearsNHLBITrait
01-DK-N117Family Investigation of Nephropathy and Diabetes (F.I.N.D.)Participants currently recruited/enrolled18-99 YearsNIDDKTrait
01-CC-0045Studies of Phlebotomy Therapy in Hereditary HemochromatosisNo longer recruiting/follow-up only18-125 YearsCC Hemoglobin
96-H-0100Role of Genetic Factors in the Pathogenesis of Lung DiseaseParticipants currently recruited/enrolled2-90 YearsNHLBIQuantitative
95-I-0066Genetic Analysis of Immune DisordersParticipants currently recruited/enrolled0-101 YearsNIAIDFetal
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