Protocol Details
Evaluation, Treatment, and Monitoring of Patients With Known or Suspected Parasitic Infection
This study is currently recruiting participants.
Summary
Number |
97-I-0096 |
Sponsoring Institute |
National Institute of Allergy and Infectious Diseases (NIAID) |
Recruitment Detail |
Type: Participants currently recruited/enrolled
Gender: Male & Female
Min Age: 3 Years
Max Age: N/A |
Referral Letter Required |
Yes |
Population Exclusion(s) |
None |
Keywords |
Helminth Infection;
Parasite;
Known Parasitic Infection;
Suspected Parasitic Infection;
Natural History |
Recruitment Keyword(s) |
None |
Condition(s) |
Malaria;
Intestinal Worms;
GI Protozoa;
Echiniococcus;
Strongyloides |
Investigational Drug(s) |
None |
Investigational Device(s) |
None |
Intervention(s) |
None |
Supporting Site |
National Institute of Allergy and Infectious Diseases |
The purpose of this study is to evaluate, treat and follow patients with parasitic infections.
People with a known or suspected parasitic infection who are at least 1 year old may be enrolled. This study does not involve any experimental treatments.
Participants will have a physical examination and laboratory tests on blood, stool, or urine. Blood samples may be collected at regular intervals, but no more than 450 ml (15 ounces) of blood will be drawn from adults, and no more than 7 ml (1-1/2 teaspoons) per kg (2.2 pounds) of body weight from children, in any 6-week period. Other tests may include x-rays, electrocardiogram (EKG), or tissue biopsy (surgical removal of a small tissue sample), depending on the individual s condition.
Patients may be offered treatment or may be referred to another study that is more appropriate for the problem. Any treatment provided in this study will be according to standard medical practice for the patient s specific medical problem. Patients responses to treatment will be evaluated at regularly scheduled clinic visits. The length of time between visits and the total duration of the study for a given individual will be determined by the study doctor, based on that person s medical condition.
Eligibility
INCLUSION CRITERIA:
Age 3 or over.
Access to a primary medical care provider outside of the NIH
Clinical evidence suggestive of a parasitic infection
EXCLUSION CRITERIA:
Less than 3 years of age
No evidence suggestive of a parasitic infection
Citations:
Nutman TB. Human infection with Strongyloides stercoralis and other related Strongyloides species. Parasitology. 2017 Mar;144(3):263-273. doi: 10.1017/S0031182016000834. Epub 2016 May 16.
O'Connell EM, Nutman TB. Eosinophilia in Infectious Diseases. Immunol Allergy Clin North Am. 2015 Aug;35(3):493-522. doi: 10.1016/j.iac.2015.05.003.
Nash TE, Ohl CA, Thomas E, Subramanian G, Keiser P, Moore TA. Treatment of patients with refractory giardiasis. Clin Infect Dis. 2001 Jul 1;33(1):22-8. Epub 2001 May 23.
Contacts:
Clinical Trials Number:
NCT00001645