Protocol Details
Fasting Hypoglycemia: Diagnosis and Treatment
This study is currently recruiting participants.
Summary
Number | 91-DK-0066 |
Sponsoring Institute | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) |
Recruitment Detail | Type: Participants currently recruited/enrolled
Gender: Male & Female
Min Age: 18 Years
Max Age: 120 Years |
Referral Letter Required | No |
Population Exclusion(s) | Fetuses;
Children;
Pregnant Women |
Keywords | Hypoglycemia;
Insulinoma;
Natural History |
Recruitment Keyword(s) | None |
Condition(s) | Hypoglycemia;
Insulinoma |
Investigational Drug(s) | None |
Investigational Device(s) | None |
Intervention(s) | None |
Supporting Site | National Institute of Diabetes and Digestive and Kidney Diseases |
Hypoglycemia is the term used to refer to lower than normal levels of blood sugar. This study will continue to research the causes of hypoglycemia.
Patients involved in the study will be admitted to the Clinical Center of the National Institutes of Health and undergo tests for evaluating blood sugar. Patients will be required to refrain from eating for a set period of time and will undergo blood tests for insulin levels and several other specific diagnostic tests related to insulin secretion. The patients will be under supervision and will be provided with appropriate medical and surgical attention as needed.
Eligibility
INCLUSION CRITERIA: In order to be eligible to participate in this study, an individual must meet all of the following criteria:
1. Male, females ages >= 18.
2. Patients with documented fasting blood glucose below 55 mg/dl.
4. Patients with biochemical evidence for insulinoma or other pancreatic neuroendocrine tumors.
EXCLUSION CRITERIA:
An individual who meets any of the following criteria will be excluded from participation in this study:
1. Patients with significant cardiac disease will be excluded.
2. Subjects who are pregnant per self-report.
3. Medically unstable per the assessment of the PI.
Citations:
Insulin receptors in patients with insulinomas: changes in receptor affinity and concentration Reactive hypoglycemia and insulin autoantibodies in drug-induced lupus erythematosis Approach to hypoglycemia in adults
Contacts:
Clinical Trials Number:
NCT00001276