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Protocol Details

A Rigid Body Database on Human Movement

This study is currently recruiting participants.

Summary | Eligibility | Citations | Contacts

Summary

Number

90-CC-0168

Sponsoring Institute

National Institutes of Health Clinical Center (CC)

Recruitment Detail

Type: Participants currently recruited/enrolled
Gender: Male & Female
Min Age: 1 Mo
Max Age: 99 Years

Referral Letter Required

No

Population Exclusion(s)

Pregnant Women

Keywords

Biomechanics;
Kinesiology;
Walking;
Natural History

Recruitment Keyword(s)

None

Condition(s)

Movement Disorder

Investigational Drug(s)

None

Investigational Device(s)

None

Intervention(s)

None

Supporting Site

NIH Clinical Center

This study will collect information on the different ways people control limb and body movements. This information will be used to develop a database on normal movements and adaptive movements of people who have diseases that affect the way they move. The database will serve as a tool to improve diagnosis and treatment of patients with movement-related problems.

Volunteers from one month old to old age who have normal movement patterns or who have developed different ways to perform movement tasks may be eligible for this study. A physician or physical therapist will screen candidates to determine their strength, flexibility and range of motion of joints.

Participants will be asked to perform movements such as walking, walking up or down stairs, standing quietly or reaching for an object or using treadmill. For the test, the arms and legs are wrapped with a soft, rubber-like material to which small plastic reflective balls are attached. A piece of firm material called a shell may be attached to the rubber sleeves or other areas of the body. Then the volunteer performs the specified task several times while special cameras record the movement. These cameras will record the positions of the reflective balls during movement and may show the person s face or body. Electrical activity in the muscles also may be measured, using small metal electrodes attached to the surface of the skin with an adhesive bandage.

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Eligibility

INCLUSION CRITERIA:

Individuals with neuromuscular disorders and Healthy Volunteers in order to be eligible to participate in this study, must meet all of the following criteria:

-Children; One month old to 17 years of age

--In the case of infants and very young children, they need to be able to imitate or perform an action on cue (e.g., reach out for a toy that is presented or take steps if placed on a treadmill) based on the parent report if the subject is a child and physician observation during history and physical examination.

-Adults; 18 years 99 years

-In good general health as evidenced by medical history or diagnosed with impairment of neuromusculoskeletal system

-Stated willingness to comply with all study procedures and availability for the duration of the study

-Provision of signed and dated informed consent form

-For those participants older than 5 years of age who have an abnormal gait pattern when walking as a result of a central nervous system injury, Dr. Alter will ask them or their guardian about their seizure history

EXCLUSION CRITERIA:

Individuals with neuromuscular disorders and Healthy Volunteers, who meets any of the following criteria will be excluded from participation in this study:

-Individuals with pacemakers

-Pregnancy

-Adults unable to provide informed consent


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Citations:

Gait as a total pattern of movement

Flexibility of anticipatory postural adjustments revealed by self-paced and reaction-time arm movements

Locomotion of autistic adults

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Contacts:

Principal Investigator

Referral Contact

For more information:

Diane L. Damiano, Ph.D.
National Institutes of Health Clinical Center (CC)
National Institutes of Health
Building 10
Room 1-1469
10 Center Drive
Bethesda, Maryland 20892
(301) 451-7544
damianod@cc.nih.gov

Mayra J. Medrano
National Institutes of Health Clinical Center (CC)
National Institutes of Health
Building 10
Room 1-1469
10 Center Drive
Bethesda, Maryland 20892
(301) 451-7529
mayra.medrano@nih.gov

Office of Patient Recruitment
National Institutes of Health Clinical Center (CC)
Building 61, 10 Cloister Court
Bethesda, Maryland 20892
Toll Free: 1-800-411-1222
Local Phone: 301-451-4383
TTY: TTY Users Dial 7-1-1
ccopr@nih.gov

Clinical Trials Number:

NCT00001252

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