This study is NOT currently recruiting participants.
Number
20-HG-0090
Sponsoring Institute
National Human Genome Research Institute (NHGRI)
Recruitment Detail
Type: Clinical hold/Recruitment or enrollment suspended Gender: Male & Female Min Age: 1 Mo Max Age: N/A
Referral Letter Required
Yes
Population Exclusion(s)
None
Keywords
SARS-CoV-2; Whole Exome Sequencing; Coronavirus 2019; Natural History
Recruitment Keyword(s)
Condition(s)
COVID-19; Coronavirus 2019
Investigational Drug(s)
Investigational Device(s)
Intervention(s)
Supporting Site
National Human Genome Research Institute
Coronavirus 2019 (COVID-19, or SARS-CoV-2) is a serious public health problem, and genetics may play a role in how serious the illness becomes in certain people. Genes are the instructions that our body uses to grow and develop. Variations in our genes can cause medical conditions and may be the reason why some people get sicker than others.
Objective:
This study aims to learn more about the genetic contributions to the severity of COVID-19. We hope to use this information to develop therapies that reduce the severity of COVID-19 symptoms in some people.
Eligibility:
Anyone located in the United States who has tested positive for SARS-CoV-2 infection may be eligible to join (including NIH staff).
Design:
Participants will complete a questionnaire about their health history and COVID-19 symptoms.
Participants will give a blood or saliva sample. It will be about 2 tablespoons of blood, or we will send a saliva collection kit. Researchers will use this blood or saliva sample to study the participant s DNA.
The data about participants genes will be stored in a large database. The database will be shared with other qualified researchers who are trying to learn about COVID-19. Participants names and other personal details will not be shared. Instead, the data will be labeled with a code.
Participants may be contacted by study team members for up to a year after they join the study.
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INCLUSION CRITERIA - Cohort 1 (Existing NIH Clinical Center Patient/Participants invited to participate by their NIH study team) -Cohort 2 (Individuals recruited through NIH Occupational Medicine Services (OMS) patients referred by NIH investigators or other providers; individuals who self-refer) -Located in the United States -Positive test for SARS-CoV-2 virus infection -Age greater than or equal to 3 years old *only for participants providing a blood sample EXCLUSION CRITERIA: -Individuals for whom we cannot consent for participation in a language offered by our existing interpretation service. -Weight less than 10 kg*
- Cohort 1 (Existing NIH Clinical Center Patient/Participants invited to participate by their NIH study team)
-Cohort 2 (Individuals recruited through NIH Occupational Medicine Services (OMS) patients referred by NIH investigators or other providers; individuals who self-refer)
-Located in the United States
-Positive test for SARS-CoV-2 virus infection
-Age greater than or equal to 3 years old
*only for participants providing a blood sample
EXCLUSION CRITERIA:
-Individuals for whom we cannot consent for participation in a language offered by our existing interpretation service.
-Weight less than 10 kg*
Principal Investigator
Referral Contact
For more information: