NIH Clinical Center Search the Studies: Study Number, Study Title

Protocol Details

Pilot Study for Geospatial Analysis of Neighborhood Environmental Stress in Relation to Biological Markers of Cardiovascular Health and Health Behaviors in Women

This study is currently recruiting participants.

Summary | Eligibility | Citations | Contacts




Sponsoring Institute

National Heart, Lung and Blood Institute (NHLBI)

Recruitment Detail

Type: Participants currently recruited/enrolled
Gender: Female
Min Age: 19 Years
Max Age: 45 Years

Referral Letter Required


Population Exclusion(s)

Native Hawaiian/Pacific Islander;
Hispanic or Latino;
American Indian or Alaskan Native;
Non-English Speaking;


Neighborhood Environment;
Cardiovascular Disease Risk;
Social Determinants of Health;
Diagnostic Behavioral study;
Natural History

Recruitment Keyword(s)



Cardiovascular (CV) Risk

Investigational Drug(s)


Investigational Device(s)




Supporting Site

National Heart, Lung, and Blood Institute


Heart disease is a leading cause of death in the United States. Healthy diet and exercise improve heart health. Some features of where a person lives can lead to stress and decrease chances for exercise. Researchers want to see how these factors may increase the risk of heart disease in women.


To see if there are differences in stress levels between women who live in different parts of Washington, DC. Also, to see how these women use their neighborhoods for exercise.


Healthy white or black females ages 19-45 who live in Washington, DC, who have access to a smartphone


Participants may stay at the NIH Clinical Center overnight for a 2-day visit.

Visit 1 will include:

Physical exam

Blood tests

Electrocardiogram: Electrodes on the participant s skin will measure heart activity.

PET/CT scan: Participants will get an injection. They will lie in a machine that takes pictures of the body.


Body size measurements

Nutrition consultation

Blood vessel tests: This is measured with blood pressure cuffs, a device placed on the participant s fingertip, and a probe placed on the participant s neck.

Resting Energy Expenditure: Participants will breathe under a clear hood for 45 minutes.

Participants will be followed for about 2 weeks. They will wear a device on the wrist and carry a GPS device. Through a mobile app, they will answer short daily surveys on stress and exercise.

Visit 2-

Device return

Nutritional consultation

--Back to Top--



Individuals eligible for this protocol:

1) A healthy self-identified White female (i.e. self-identifies as White or of European descent) or healthy Black female (i.e. self-identifies as Black, African American, or of African descent)

2) Must be between 19 to 45 years of age

3) Must not have any chronic health condition, including lung disease or active infection

4) Must be living in Washington, DC

5) Must have access to a smartphone

6) Must be able to provide informed consent

7) Must speak English.


1) If you are pregnant or breast feeding

2) If you are physically unable to perform physical activity for any reason

3) If you have had weight changes greater than 20% over the past 3 months

4) If you are obese by our measurements (BMI greater than or equal to 35.0 kg/m^2)

5) If you have high or low blood pressure

6) If you have diabetes

7) If you have a history of severe mental illnesses, treated with hospitalization

8) If you have a history or evidence of hyper/hypothyroidism

9) If you are taking medication for chronic non-mental health related illness

10) If you have food allergies or highly restrictive diets that may prevent your ability to consume a controlled metabolic diet.

11) If you are a smoker

--Back to Top--


Not Provided

--Back to Top--


Principal Investigator

Referral Contact

For more information:

Tiffany M. Powell-Wiley, M.D.
National Heart, Lung and Blood Institute (NHLBI)
NIHBC 10 - CRC BG RM 5-3340
(301) 594-3735

Marie Marah, R.N.
National Heart, Lung and Blood Institute (NHLBI)
National Institutes of Health
Building 10
Room 7N306
10 Center Drive
Bethesda, Maryland 20892
(301) 640-1701

Office of Patient Recruitment
National Institutes of Health Clinical Center (CC)
Building 61, 10 Cloister Court
Bethesda, Maryland 20892
Toll Free: 1-800-411-1222
Local Phone: 301-451-4383
TTY: TTY Users Dial 7-1-1

Clinical Trials Number:


--Back to Top--