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Protocol Details

Natural History Study of Children and Adults with Chordoma

This study is currently recruiting participants.

Summary | Eligibility | Citations | Contacts

Summary

Number

19-C-0082

Sponsoring Institute

National Cancer Institute (NCI)

Recruitment Detail

Type: Participants currently recruited/enrolled
Gender: Male & Female
Min Age: 2 Years
Max Age: N/A

Referral Letter Required

No

Population Exclusion(s)

None

Keywords

Rare Tumor;
Comprehensive Evaluation and Recommendations;
Collecting Clinical, Epidemiologic and Biological Data;
Natural History

Recruitment Keyword(s)

None

Condition(s)

Chordoma

Investigational Drug(s)

None

Investigational Device(s)

None

Intervention(s)

None

Supporting Site

National Cancer Institute

Background:

Chordoma is a rare type of bone cancer. It occurs in the skull base or spine. Researchers want to study people with chordoma in different ways. They hope this will help them design better future treatments and supportive care studies for this disease.

Objective:

To learn more about chordoma by looking at its clinical course, how it appears on imagine scans, and how it responds to therapies and treatments.

Eligibility:

People ages 2 and older with chordoma who are enrolled in NCI protocol 19-C-0016

Design:

Participants will be screened with their medical history.

Participants will have a visit to examine their disease. This will include:

--Physical exam

--Neurologic exam

--CT scan and MRI: Participants will lie on a table. The table will slide into a machine. The machine will take pictures of the body.

Participants will have other tests every 6-12 months:

--Smell test

--Surveys to assess their emotional, physical, and behavioral well-being and needs

--Cognitive function tests

Participants or their home doctors will be contacted every 6 12 months. They will be asked to provide information about their disease. This could include test results and imaging evaluations.

Some participants may be asked to come to the clinic for more visits.

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Eligibility

INCLUSION CRITERIA:

-Ability of subject or Legally Authorized Representative (LAR) to understand and the willingness to sign a written consent document.

-Subjects with radiographically or histologically documented chordoma

-Age greater than or equal to 2 years old

-Subjects must be enrolled into NCI protocol 19-C-0016: Natural History and Biospecimen Acquisition Study for Children and Adults with Rare Solid Tumors .

EXCLUSION CRITERIA:

-None


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Citations:

Not Provided

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Contacts:

Principal Investigator

Referral Contact

For more information:

Mary F. Wedekind Malone, D.O.
National Cancer Institute (NCI)
NIHBC 10 - CRC BG RM 1-3750
10 CENTER DR
BETHESDA MD 20892
(240) 858-3765
maryfrances.wedekindmalone@nih.gov

Barbara (BJ) Thomas, R.N.
National Cancer Institute (NCI)
National Institutes of Health
Building 10
Room 1-3750
10 Center Drive
Bethesda, Maryland 20892
(240) 858-3633
barbara.thomas2@nih.gov

NCI Referral Office
National Institute of Health Clinical Center (CC), 9000 Rockville Pike, Bethesda, Maryland 20892, United States: NCI Clinical Trials Referral Office
1-888-NCI-1937
ncimo_referrals@mail.nih.gov

Clinical Trials Number:

NCT03910465

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