Protocol Details

Collection of Blood from Patients with Cancer, Other Tumors, or Tumor Predisposition Syndromes for Analysis of Genetic Differences in Drug Disposition

This study is currently recruiting participants.

Summary | Eligibility | Citations | Contacts

Summary

Number	11-C-0242
Sponsoring Institute	National Cancer Institute (NCI)
Recruitment Detail	*Type:* Participants currently recruited/enrolled *Gender:* Male & Female *Min Age:* 3 Years *Max Age:* N/A
Referral Letter Required	Yes
Population Exclusion(s)	None
Keywords	Pharmacogenetics; Pharmacokinetics; Pharmacodynamics; Clinical Outcome; Drug Metabolism and Transport; Natural History
Recruitment Keyword(s)	Cancer
Condition(s)	Prostate Cancer; Breast Cancer; Lung Cancer; Ovarian Cancer; Lymphoma
Investigational Drug(s)	None
Investigational Device(s)	None
Intervention(s)	None
Supporting Site	National Cancer Institute

Background:

- Some genes may be associated with a greater chance of side effects during cancer treatment. These genes may also make certain treatments less effective. Researchers want to collect blood or cheek swab samples from people having cancer treatment to study these genes.

Objectives:

- To obtain a blood or cheek swab sample to study genetic differences that may affect cancer treatment.

Eligibility:

- Individuals with cancer who are being treated at the National Cancer Institute.

Design:

- Participants will provide a blood sample for study.

- Participants who have blood-based cancer, such as leukemia, will provide a cheek swab sample.

- If the blood or cheek swab sample does not have enough genetic material for analysis, an additional sample may be collected.

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Eligibility

INCLUSION CRITERIA:

Patients with cancer, other tumors, or tumor predisposition syndromes currently enrolled in NIH intramural research program therapeutic trials.

Ability of participant or Legally Authorized Representative (LAR) to understand and be willing to sign the informed consent document.

Age >= 3 years old

EXCLUSION CRITERIA:

N/A

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Citations:

Not Provided

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Contacts:

Principal Investigator	Referral Contact	For more information:
William D. Figg, Pharm.D. National Cancer Institute (NCI) National Institutes of Health Building 10 Room 5A01 10 Center Drive Bethesda, Maryland 20892 (240) 760-6179 figgw@mail.nih.gov	Deneise Francis, R.N. National Cancer Institute (NCI) National Institutes of Health Building 10 Room 13N222 10 Center Drive Bethesda, Maryland 20892 (240) 858-3974 deneise.francis@nih.gov	NCI Referral Office National Institute of Health Clinical Center (CC), 9000 Rockville Pike, Bethesda, Maryland 20892, United States: NCI Clinical Trials Referral Office 1-888-NCI-1937 ncimo_referrals@mail.nih.gov

Clinical Trials Number:

NCT01441089

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