This study is currently recruiting participants.
Number
08-I-0221
Sponsoring Institute
National Institute of Allergy and Infectious Diseases (NIAID)
Recruitment Detail
Type: Enrolling by Invitation Gender: Male & Female Min Age: 18 Years Max Age: N/A
Referral Letter Required
Yes
Population Exclusion(s)
Children
Keywords
HIV; Natural History; Natural History
Recruitment Keyword(s)
None
Condition(s)
HIV
Investigational Drug(s)
Investigational Device(s)
Intervention(s)
Supporting Site
National Institute of Allergy and Infectious Diseases
HIV-infected patients who are 18 years of age or older, have been enrolled in another NIH protocol, have been suppressed on antiretroviral therapy and have very low levels of virus in their blood may be eligible for this 5-year (or more) study.
Participants come to the NIH Clinical Center about every 6 months for a physical examination, routine and research blood tests and leukapheresis to collect white blood cells for T cell analysis. For leukapheresis, blood is collected through a vein much like donating whole blood, but the blood is directed through a machine that separates and extracts the white cells and returns the rest of the blood components to the patient. Patients may also have an optional third clinic visit each year for another blood draw.
--Back to Top--
INCLUSION CRITERIA: Inclusion criteria for this protocol comprise all of the following conditions: - Age greater than or equal to 18 years. - HIV infection with documented reactive ELISA and positive western blot. - Prior enrollment in 00-I-0110, 97-I-0082 OR patients with long term evaluation at NIH for whom additional sampling will be useful for protocol objectives, including: -- Available stored specimens from pretherapy period. -- Ongoing suppression of viremia with bDNA less than 50 copies/mL, OR -- Suppression of viremia to less than 50 copies/mL followed by rebound viremia during therapy. - Patients must have a private physician for routine medical care. EXCLUSION CRITERIA: Any prospective study subject who has been previously withdrawn from any prior study for inability to comply with study procedures will be considered ineligible for this study.
Inclusion criteria for this protocol comprise all of the following conditions:
- Age greater than or equal to 18 years.
- HIV infection with documented reactive ELISA and positive western blot.
- Prior enrollment in 00-I-0110, 97-I-0082 OR patients with long term evaluation at NIH for whom additional sampling will be useful for protocol objectives, including:
-- Available stored specimens from pretherapy period.
-- Ongoing suppression of viremia with bDNA less than 50 copies/mL, OR
-- Suppression of viremia to less than 50 copies/mL followed by rebound viremia during therapy.
- Patients must have a private physician for routine medical care.
EXCLUSION CRITERIA:
Any prospective study subject who has been previously withdrawn from any prior study for inability to comply with study procedures will be considered ineligible for this study.
Principal Investigator
Referral Contact
For more information: