Protocol Details

Human Specimen Collection to Support Basic and Clinical Research

This study is currently recruiting participants.

Summary | Eligibility | Citations | Contacts

Summary

Number	03-H-0015
Sponsoring Institute	National Heart, Lung and Blood Institute (NHLBI)
Recruitment Detail	*Type:* Enrolling by Invitation *Gender:* Male & Female *Min Age:* 18 Years *Max Age:* 100 Years
Referral Letter Required	No
Population Exclusion(s)	Children
Keywords	DNA; Endothelial Function; Leukocyte Gene Expression; RNA; Natural History
Recruitment Keyword(s)	Sickle Cell; Coronary Artery Disease; CAD; Healthy Volunteer; HV
Condition(s)	Sickle Cell Disease
Investigational Drug(s)	None
Investigational Device(s)	None
Intervention(s)	None
Supporting Site	National Heart, Lung and Blood Institute

The collection of human specimens from both patients and healthy volunteers is necessary for the development of laboratory assays to further basic and clinical research studies. This protocol defines the purposes for which specimens will be collected and establishes general conditions under which sample collection will be performed.

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Eligibility

INCLUSION CRITERIA:

Males or females of age 18 years and older can be included in the study.

EXCLUSION CRITERIA:

Individuals without sickle cell disease or other chronic anemias who wish to donate blood will be excluded if the hemoglobin is less than 10 g/dL for women or less than 12g/dL for men.

Individuals with sickle cell disease or other chronic anemias will be excluded from donating blood samples if the hemoglobin is less than 6 g/dL.

A participant s most recent CBC result, obtained in the past 12 months, will be used to determine eligibility.

There are no exclusion criteria for participants donating saliva or urine.

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Citations:

Not Provided

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Contacts:

Principal Investigator	Referral Contact	For more information:
Swee Lay Thein, M.D. National Heart, Lung and Blood Institute (NHLBI) NIHBC 10 - CLINICAL CENTER BG RM 6S241A 10 CENTER DR BETHESDA MD 20892 (301) 435-2345 sweelay.thein@nih.gov	Anna K. Conrey, C.R.N.P. National Heart, Lung and Blood Institute (NHLBI) NIHBC 10 - CLINICAL CENTER BG RM 6N240D 10 CENTER DR BETHESDA MD 20892 (301) 221-3016 anna.conrey@nih.gov	Office of Patient Recruitment National Institutes of Health Clinical Center (CC) Building 61, 10 Cloister Court Bethesda, Maryland 20892 Toll Free: 1-800-411-1222 Local Phone: 301-451-4383 TTY: TTY Users Dial 7-1-1 ccopr@nih.gov

Clinical Trials Number:

NCT00047996

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