This study is currently recruiting participants.
Number
02-C-0064
Sponsoring Institute
National Cancer Institute (NCI)
Recruitment Detail
Type: Enrolling by Invitation Gender: Male & Female Min Age: 18 Years Max Age: 120 Years
Referral Letter Required
No
Population Exclusion(s)
Children
Keywords
Blood; Samples; Radiation; Urine; Cancer; Natural History
Recruitment Keyword(s)
None
Condition(s)
Carcinoma; Cancer; Tumor
Investigational Drug(s)
Investigational Device(s)
Intervention(s)
Supporting Site
National Cancer Institute
-Research in NCI's Radiation Oncology Branch depends on the availability of blood and urine samples from patients receiving radiation therapy.
Objectives:
-To explore the effects of radiation therapy on gene expression in white blood cells, to measure radiation damage in red blood cells and to examine changes in hormone levels in the blood and urine after radiation therapy.
Eligibility:
-Patients 18 years of age and older who are receiving radiation therapy.
Design:
-Blood and urine samples are collected when participants enter the study.
-Additional samples may be collected at different times during and after treatment. Ideally, samples are obtained before, at the completion of, and 1 month following radiation therapy. Blood samples usually will be collected during routine patient monitoring procedures and will not require an additional needle stick.
-A total of 300 patients will be studied at the NCI in Bethesda, MD, Johns Hopkins University in Baltimore and the University of Pennsylvania in Philadelphia.
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INCLUSION CRITERIA: 1. Patients must be co-enrolled in a NIH CC protocol in which radiation will be administered. 2. Patients must a candidate for, or currently receiving radiotherapy. 3. Age greater than or equal to 18 years. 4. Ability of subject or Legally Authorized Representative (LAR) to understand and the willingness to sign a written informed consent document. EXCLUSION CRITERIA: 1. Patients who have unobtainable data regarding previous radiation therapy.
1. Patients must be co-enrolled in a NIH CC protocol in which radiation will be administered.
2. Patients must a candidate for, or currently receiving radiotherapy.
3. Age greater than or equal to 18 years.
4. Ability of subject or Legally Authorized Representative (LAR) to understand and the willingness to sign a written informed consent document.
EXCLUSION CRITERIA:
1. Patients who have unobtainable data regarding previous radiation therapy.
Principal Investigator
Referral Contact
For more information: