Protocol Details
Studies of the Natural History of Rheumatic Diseases
This study is currently recruiting participants.
Summary
Number | 01-AR-0227 |
Sponsoring Institute | National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) |
Recruitment Detail | Type: Participants currently recruited/enrolled
Gender: Male & Female
Min Age: 18 Years
Max Age: 100 Years |
Referral Letter Required | No |
Population Exclusion(s) | Children |
Keywords | Minorities;
Rheumatic Disease;
Community Based;
Natural History |
Recruitment Keyword(s) | Rheumatic Disease;
Ethnicity;
Health Disparities |
Condition(s) | Rheumatic Diseases;
Arthritis |
Investigational Drug(s) | None |
Investigational Device(s) | None |
Intervention(s) | None |
Supporting Site | National Institute of Arthritis and Musculoskeletal and Skin Diseases |
This study will explore the causes of rheumatic diseases and why many of them affect certain minority communities more severely. Rheumatic diseases may cause joint pain, stiffness or swelling. Some can involve bones, muscles, tendons or ligaments. Some cause abnormalities of the immune system-the body s defense against disease. Some rheumatic diseases are painful or deforming and some can be life threatening. Information obtained from this study will be used to learn about the disparities in rheumatic disease in the minority community and to design further, more targeted, research studies to address this issue.
Patients with known or suspected rheumatic disease 18 years of age or older may be eligible for this study. Candidates will undergo a medical history and physical examination to confirm the diagnosis of rheumatic disease and determine what is needed for evaluation and treatment.
Participants will receive standard medical care for rheumatic disease and arthritis. No experimental treatments, medications or procedures will be included in this study. Procedures may include routine blood tests for blood chemistries, cell counts, and antibodies commonly found in patients with rheumatic disease; a urine test for proteins and cells; and X-rays and other imaging tests to check for abnormalities in the lungs or other organs. All medical information will be kept confidential.
Patients who are found to be eligible for other current NIH research studies will be offered an opportunity to participate in these studies.
Eligibility
INCLUSION CRITERIA:
Known or suspected rheumatic disease
Age greater than or equal to 18 years
Willingness and capacity to provide informed consent.
EXCLUSION CRITERIA:
Patients will be excluded if any of the inclusion criteria cannot be met.
Women who are pregnant or breastfeeding at the time of enrollment.
Citations:
Systemic lupus erythematosus in three ethnic groups: I The effects of HLA class II, C4, and CR1 alleles, socioeconomic factors, and ethnicity at disease onset LUMINA Study Group Lupus in minority populations, nature versus nurture Estimates of the prevalence of arthritis and selected musculoskeletal disorders in the United States Effect of race and ethnicity on outcomes in arthritis and rheumatic conditions
Contacts:
Clinical Trials Number:
NCT00024479