Protocol Details

Studies of the Natural History of Rheumatic Disease in Minority Communities

This study is currently recruiting participants.

Summary | Eligibility | Citations | Contacts

Summary

Number	01-AR-0227
Sponsoring Institute	National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Recruitment Detail	Type: Participants currently recruited/enrolled Gender: Male & Female Min Age: 18 Years Max Age: 100 Years
Referral Letter Required	No
Population Exclusion(s)	Children
Keywords	Minorities; Rheumatic Disease; Community Based; Natural History
Recruitment Keyword(s)	Rheumatic Disease; Ethnicity; Health Disparities
Condition(s)	Rheumatic Diseases; Arthritis
Investigational Drug(s)	None
Investigational Device(s)	None
Intervention(s)	None
Supporting Site	National Institute of Arthritis and Musculoskeletal and Skin Diseases

This study will explore the causes of rheumatic diseases and why many of them affect certain minority communities more severely. Rheumatic diseases may cause joint pain, stiffness or swelling. Some can involve bones, muscles, tendons or ligaments. Some cause abnormalities of the immune system the body s defense against disease. Some rheumatic diseases are painful or deforming and some can be life threatening. Information obtained from this study will be used to learn about the disparities in rheumatic disease in the minority community and to design further, more targeted, research studies to address this issue.

Patients with known or suspected rheumatic disease 18 years of age or older may be eligible for this study. Candidates will undergo a medical history and physical examination to confirm the diagnosis of rheumatic disease and determine what is needed for evaluation and treatment.

Participants will receive standard medical care for rheumatic disease and arthritis. No experimental treatments, medications or procedures will be included in this study. Procedures may include routine blood tests for blood chemistries, cell counts, and antibodies commonly found in patients with rheumatic disease; a urine test for proteins and cells; and X-rays and other imaging tests to check for abnormalities in the lungs or other organs. All medical information will be kept confidential.

Patients who are found to be eligible for other current NIH research studies will be offered an opportunity to participate in these studies.

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Eligibility

INCLUSION CRITERIA:

Known or suspected rheumatic disease

Age greater than or equal to 18 years

Willingness and capacity to provide informed consent.

EXCLUSION CRITERIA:

Patients will be excluded if any of the inclusion criteria cannot be met.

Women who are pregnant or breastfeeding at the time of enrollment.

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Citations:

Systemic lupus erythematosus in three ethnic groups: I The effects of HLA class II, C4, and CR1 alleles, socioeconomic factors, and ethnicity at disease onset LUMINA Study Group Lupus in minority populations, nature versus nurture

Estimates of the prevalence of arthritis and selected musculoskeletal disorders in the United States

Effect of race and ethnicity on outcomes in arthritis and rheumatic conditions

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Contacts:

Principal Investigator	Referral Contact	For more information:
Sarfaraz A. Hasni, M.D. National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) NIHBC 10 - CRC BG RM 3-2340 10 CENTER DR BETHESDA MD 20892 (301) 451-1599 hasnisa@mail.nih.gov	Nancy A. Spencer National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) National Institutes of Health Building 10 Room 4-1339 10 Center Drive Bethesda, Maryland 20892 (301) 827-0186 nancy.spencer@nih.gov	Office of Patient Recruitment National Institutes of Health Clinical Center (CC) Building 61, 10 Cloister Court Bethesda, Maryland 20892 Toll Free: 1-800-411-1222 Local Phone: 301-451-4383 TTY: TTY Users Dial 7-1-1 ccopr@nih.gov

Clinical Trials Number:

NCT00024479

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