Protocol Details

Predicting Future Errors During Skill Performance

This study is currently recruiting participants.

Summary | Eligibility | Citations | Contacts

Summary

Number

002017-N

Sponsoring Institute

National Institute of Neurological Disorders and Stroke (NINDS)

Recruitment Detail

Type: Participants currently recruited/enrolled
Gender: Male & Female
Min Age: 18 Years
Max Age: 35 Years

Referral Letter Required

No

Population Exclusion(s)

Adults who are or may become unable to consent;
Pregnant Women;
Non-English Speaking;
Children

Keywords

Healthy;
Brain;
Motor Skill

Recruitment Keyword(s)

None

Condition(s)

Healthy

Investigational Drug(s)

None

Investigational Device(s)

None

Intervention(s)

None

Supporting Site

National Institute of Neurological Disorders and Stroke

Background:

Many tasks people do every day require a series of individual movements. Control over these movements is called motor skills. But even highly skilled people can make mistakes. Researchers have found that they can predict when a person will make a mistake 0.1 second before it happens. Now, they want to find out if they can increase that time up to 1 second-long enough to warn the person and prevent the mistake.

Objective:

To see if motor skill errors can be detected up to 1 second before they occur.

Eligibility:

Right-handed healthy adults aged 18 to 35.

Design:

Participants will have 2 to 5 study visits. Each visit will be 1 to 2 hours.

They will have a physical and neurological exam.

They will have 1 or 2 magnetic resonance imaging (MRI) scans. They will lie on a table that slides into a large cylinder. The MRI uses strong magnets to capture images of the inside of the body, including the brain.

They will have another scan, called magnetoencephalography (MEG). Small metal disks attached to wires will be taped to their head. Participants will sit in a padded chair with their head inside of a helmet. The helmet will not cover their eyes or face. Participants will perform a series of typing tasks on a keyboard. They will have short breaks between each round. Their head movements will be tracked, and their eye and finger movements will be videotaped.

Eligibility

INCLUSION CRITERIA:

In order to be eligible to participate in this study, an individual must meet all of the following criteria:

-Stated willingness to comply with all study procedures and availability for the duration of the study

-Male or female, aged 18-35

-In good general health as evidenced by medical history and normal neurological examination as determined by the screening clinician

-English speaking

-Right-handedness as reported by participant

-Ability of subject to understand and the willingness to sign a written informed consent document

EXCLUSION CRITERIA:

An individual who meets any of the following criteria will be excluded from participation in this study:

-HCPS-affiliated NIH staff (i.e. - staff from our section)

-Current pregnancy

-Contraindications for MRI, or MEG

-Severe or progressive neurological, psychological or medical condition as determined by the medical history review or physical and neurological exam.


Citations:

Not Provided

Contacts:

Principal Investigator

Referral Contact

For more information:

Leonardo G. Cohen, M.D.
National Institute of Neurological Disorders and Stroke (NINDS)
NIHBC 10 - CLINICAL CENTER BG RM 7D54
10 CENTER DR
BETHESDA MD 20892
(301) 496-9782
cohenl1@mail.nih.gov
Catherine L. Blumhorst, C.R.N.P.
National Institute of Neurological Disorders and Stroke (NINDS)
NIHBC 10 - CRC BG RM 2-1339
10 CENTER DR
BETHESDA MD 20892
(301) 451-1335
cathy.blumhorst@nih.gov
Office of Patient Recruitment
National Institutes of Health Clinical Center (CC)
Building 61, 10 Cloister Court
Bethesda, Maryland 20892
Toll Free: 1-800-411-1222
Local Phone: 301-451-4383
TTY: TTY Users Dial 7-1-1
ccopr@nih.gov

Clinical Trials Number:

NCT06707207
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