Protocol Details
Screening Protocol for Clinical Trial Eligibility
This study is currently recruiting participants.
Summary
Number |
001863-C |
Sponsoring Institute |
National Cancer Institute (NCI) |
Recruitment Detail |
Type: Participants currently recruited/enrolled
Gender: Male & Female
Min Age: 18 Years
Max Age: 120 Years |
Referral Letter Required |
No |
Population Exclusion(s) |
Children;
Pregnant Women;
Neonates |
Keywords |
Chimeric antigen receptors (CAR-T);
Tumor infiltrating lymphocyte (TIL);
Cellular Therapy;
Gene Therapy |
Recruitment Keyword(s) |
None |
Condition(s) |
Immunotherapy;
Human Papillomavirus |
Investigational Drug(s) |
None |
Investigational Device(s) |
None |
Intervention(s) |
None |
Supporting Site |
National Cancer Institute |
Background:
Immunotherapy is a type of treatment that helps a person s own immune system to fight cancer. Some tumor cells produce high levels of specific antigens. Antigens are proteins or other substances that provoke an immune response. Immunotherapy involves collecting a person s own immune cells, such as white blood cells; these cells are then changed to be better at targeting the antigens on their cancer cells. To test new immunotherapies, researchers want to find people with cancer that has specific antigens and other characteristics.
Objective:
To screen people who might be eligible for clinical trials to treat cancer with immunotherapy. These trials will be held at the NIH or at Rutgers Cancer Institute of New Jersey.
Eligibility:
People aged 18 years or older who have cancer. The cancer must be eligible for immunotherapy trials.
Design:
Participants' medical records will be reviewed. This review will include results of blood tests; imaging scans; photographs or videos; and reports on tissue samples.
Participants may have the following samples collected for testing:
Blood. About 3 tablespoons of blood will be drawn from a vein in the arm. The blood will be tested to find the participant s tissue type.
Tumor tissue. If a recent one is not available, a new tissue sample may be taken from the participant s tumor. The tissue will be tested for the presence of specific antigens. The tumor tissue sample may also be tested for certain genes or other molecules.
Eligibility
ELIGIBILITY:
-Age >= 18 years of age.
-Ability and willingness of subject to provide informed consent.
-Biopsy proven or suspected malignant disease.
Citations:
Not Provided
Contacts: