This study is currently recruiting participants.
Number
000152-E
Sponsoring Institute
National Institute of Environmental Health Sciences (NIEHS)
Recruitment Detail
Type: Participants currently recruited/enrolled Gender: Male & Female Min Age: 18 Years Max Age: N/A
Referral Letter Required
No
Population Exclusion(s)
None
Keywords
Blood Collection; Metabolic Disease; Inflammation; Natural History
Recruitment Keyword(s)
Condition(s)
Inflammation; normal controls; Metabolic Disease
Investigational Drug(s)
Investigational Device(s)
Intervention(s)
Supporting Site
National Institute of Environmental Health Sciences
Environmental exposures like pollution, diet, and stress can help cause human diseases, or make them worse. Researchers want to better understand how injury and inflammation are caused by these exposures. They want to collect biological and environmental samples and other data. They may use the samples to measure a range of factors, like hormones, toxins, and chemicals. This will help them improve their studies.
Objective:
To identify and understand how environmental exposures contribute to human disease.
Eligibility:
Healthy adults ages 18 and older
Design:
Participants will be screened with questions about their health history, demographics, and medicines they take.
Participants may give blood, hair, stool, saliva, and/or urine samples. They may have a skin punch biopsy to collect skin cells. They may give fingernail or toenail clippings. They may give a sample of exhaled breath.
Participants may give a sputum sample. They will inhale a saline mist and cough mucus into a cup.
Participants may have their nasal passages brushed, scraped, or washed.
Participants may give cheek cell samples. They will swish mouthwash and spit it into a cup.
Participants who produce sperm may give samples.
Participants may have bronchoscopy to collect fluid. A saline solution will be put into their lung and then suctioned out, washing areas of the lung.
Participants may have a pelvic or transvaginal ultrasound. They may have lung function tests.
Participants may collect household dust, urine, or stool at home.
Participants will complete surveys about their health, diet, and exposures.
Participation will last for one or more study visits.
Participants may be contacted in the future to take part in other studies.
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INCLUSION CRITERIA: In order to be eligible to participate in this study, an individual must meet all of the following criteria: 1. Stated willingness to comply with all study procedures and availability for the duration of the study. 2. Ability to provide informed consent. 3. Able to read and speak English. 4. Male or female, aged greater than or equal to 18. 5. Able to travel to the NIEHS CRU for study visits. EXCLUSION CRITERIA: An individual who meets any of the following criteria will be excluded from participation in this study: 1. Not willing to have samples stored for future use. 2. Current pregnancy or lactation, by participant verbal confirmation. 3. Any condition that, in the investigator s opinion, places the participant at undue risk for complications associated with required study procedures.
In order to be eligible to participate in this study, an individual must meet all of the following criteria:
1. Stated willingness to comply with all study procedures and availability for the duration of the study.
2. Ability to provide informed consent.
3. Able to read and speak English.
4. Male or female, aged greater than or equal to 18.
5. Able to travel to the NIEHS CRU for study visits.
EXCLUSION CRITERIA:
An individual who meets any of the following criteria will be excluded from participation in this study:
1. Not willing to have samples stored for future use.
2. Current pregnancy or lactation, by participant verbal confirmation.
3. Any condition that, in the investigator s opinion, places the participant at undue risk for complications associated with required study procedures.
Principal Investigator
Referral Contact
For more information: