NIH Clinical Research Studies Listed By Protocol Number


Active Accrual, Protocols Recruiting New Patients 
* 17-N-0083:
Targeting Residual Activity By Precision, Biomarker-Guided Combination Therapies of Multiple Sclerosis (TRAP-MS)

* 17-N-0076:
Does N-Acetylcysteine Decrease Spontaneous Oxidation of Central Neural Dopamine in Parkinson's Disease?

* 17-N-0055:
Functional Connectivity as a Biomarker of rTMS

* 17-N-0053:
Neurophysiologic Study of Patients with Essential Tremor and Dystonic Tremor

* 17-N-0035:
Clinical and Physiological Studies of Tremor Syndromes

* 17-N-0031:
Detailed Evaluation of the Neurophysiology of Surround Inhibition in the Human Motor Cortex

* 17-N-0025:
INCEPTUS: A Prospective, Non-Interventional Clinical Assessment Study in X-Linked Myotubular Myopathy (XLMTM) Subjects Aged 3 Years and Younger

* 17-MD-0015:
Understanding How Cigarette Direct Mail Marketing Influences Smoking Behaviors Among High and Low Socioeconomic Status Young Adult Smokers

* 17-M-0060:
Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive Disorder

* 17-M-0046:
Effects of SRX246, a Vasopressin Receptor (V1a) Antagonist, on an Experimental Model of Fear and Anxiety in Humans

* 17-M-0042:
The Effect of Transcranial Magnetic Stimulation to the Dorsolateral Prefrontal Cortex on Anxiety Potentiated Startle

* 17-M-0041:
Evaluation of a Novel Positron Emission Tomography (PET) Radiotracer to Image Phosphodiesterase-4B (PDE4B)

* 17-I-0072:
Herpesviruses Reactivation In Hiv-Infected Women Initiating ART (HERA)

* 17-I-0068:
CD8 Reactivity to Microorganisms in Blood and Breast Milk

* 17-I-0067:
Sanaria PfSPZ Challenge with Pyrimethamine Chemoprophylaxis (PfSPZ-CVac Approach): Phase 1 Dose Escalation Trial to Determine Safety and Development of Protective Efficacy after Exposure to Only Pre-erythrocytic Stages of Plasmodium falciparum

* 17-I-0065:
A Phase 3, Multicenter, Expanded Access Study of Ibalizumab Plus an Optimized Background Regimen (OBR) in Treatment-Experienced Patients Infected With Multi-Drug Resistant (MDR) HIV-1

* 17-I-0059:
Randomized, Double-Blind, Placebo-Controlled, Phase 1 Study in Healthy Volunteers to Evaluate the Safety and Immunogenicity of AGS-v, a Universal Mosquito-Borne Disease Vaccine

* 17-I-0058:
VRC 317: A Phase I Randomized, Open-Label Clinical Trial to Evaluate Dose, Safety, Tolerability and Immunogenicity of a Stabilized Prefusion RSV F Subunit Protein Vaccine, VRC-RSVRGP084-00-VP (DS-Cav1), Alone or with Alum Adjuvant, in Healthy Adults

* 17-I-0047:
Treatment of Conditions Expected to Benefit from JAK 1/2 Inhibition: CANDLE, CANDLE Related Conditions, SAVI, and Severe Juvenile Dermatomyositis

* 17-I-0033:
Beginning Assessment of Cutaneous Treatment Efficacy of Roseomonas in Atopic Dermatitis Phase I/II

* 17-I-0030:
VRC 605: A Phase 1 Dose-Escalation Study of the Safety and Pharmacokinetics of a Human Monoclonal Antibody, VRC-HIVMAB075-00-AB (VRC07-523LS), Administered Intravenously or Subcutaneously to Healthy Adults

* 17-I-0024:
VRC 320: A Phase I, Randomized Clinical Trial to Evaluate the Safety and Immunogenicity of a Zika Virus DNA Vaccine, VRC-ZKADNA090-00-VP, Administered via Needle and Syringe or Needle-free Injector, PharmaJet, in Healthy Adults

* 17-I-0017:
A Phase 2a Study to Evaluate the Safety, Tolerability, and Immunogenicity of One Dose of NDV-3A Vaccine in Patients with STAT3-Mutated Hyper-IgE Syndrome

* 17-I-0016:
Studies of the Natural History, Pathogenesis, and Outcome of Autoinflammatory Diseases (NOMID/CAPS, DIRA, CANDLE, SAVI, NLRC4-MAS, Still s-like Diseases, and Other Undifferentiated Autoinflammatory Diseases)

* 17-H-0069:
Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease

* 17-H-0064:
Multicenter International Durability and Safety of Sirolimus Trial

* 17-H-0056:
Pathophysiology of Acute Pain in Patients with Sickle Cell Disease

* 17-H-0026:
Pembrolizumab and Decitabine for Refractory or Relapsed Acute Myeloid Leukemia

* 17-H-0019:
A Randomized Trial of Sirolimus (Rapamune) for Relapse Prevention in Patients with Severe Aplastic Anemia Responsive to Immunosuppressive Therapy

* 17-EI-0008:
The Natural History of Geographic Atrophy Associated with Age-Related Macular Degeneration

* 17-DK-0054:
The Physiological Responses and Adaptation of Brown Adipose Tissue to Chronic Treatment with Beta-3-Adrenergic Receptor Agonists

* 17-DK-0013:
Therapeutic Targets in African-American Youth with Type 2 Diabetes

* 17-CH-0020:
Observational Study of Males with Creatine Transporter Deficiency(CTD)

* 17-CH-0014:
Pilot Study of Mobile Attention Training in Overweight Female Adolescents

* 17-CC-0022:
Pre-Pivotal Procleix Zika Virus Assay Testing of Donations From Donors of Whole Blood and Blood Components

* 17-CC-0010:
Exploring the Influence of Psychosocial Distress and Lifetime Trauma Exposure on Traumatic Stress Among Oncology Patients on Clinical Trials

* 17-C-0090:
DART: Dual Anti-CTLA-4 And Anti-Pd-1 Blockade In Rare Tumors

* 17-C-0086:
An Open-label Phase 2 Study to Evaluate PT2385 for the Treatment of Von Hippel-Lindau Disease-Associated Clear Cell Renal Cell Carcinoma

* 17-C-0084:
A Phase II Trial of the Mitogen Activated Protein Kinase Kinase (MEK1/2) Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in Patients with Neurofibromatosis Type 1 (NF1) Mutated Gastrointestinal Stromal Tumors (GIST)

* 17-C-0074:
A Phase 2 Study of Anti-PD-L1 Antibody (Atezolizumab) in Alveolar Soft Part Sarcoma

* 17-C-0070:
Phase II Trial of Heated Intraperitoneal Chemotherapy and Gastrectomy for Gastric Cancer with Positive Peritoneal Cytology

* 17-C-0066:
A Pilot Study to Investigate the Safety and Clinical Activity of Avelumab (MSB0010718C) in Thymoma and Thymic Carcinoma after Progression on Platinum-Based Chemotherapy

* 17-C-0057:
A Randomized Phase II Trial of Standard of Care Alone or in Combination with Ad-CEA Vaccine and Avelumab in Patients with Previously Untreated Metastatic Colorectal Cancer

* 17-C-0049:
A Phase I/II Trial of the Insulin-Like Growth Factor 1 Receptor (IGF-1R) Antibody AMG479 (Ganitumab) in Combination with the Src Family Kinase (SFK) Inhibitor Dasatinib in Patients with Embryonal and Alveolar Rhabdomyosarcoma

* 17-C-0048:
T Cells Expressing a Fully-Human Anti-CD30 Chimeric Antigen Receptor for Treating CD30-Expressing Lymphomas

* 17-C-0045:
A Phase I Study of Indenoisoquinoline LMP744 in Adults With Relapsed Solid Tumors and Lymphomas

* 17-C-0044:
Prospective Evaluation and Molecular Profiling in Patients with Gastric Tumors

* 17-C-0043:
Hereditary Gastric Cancer Syndromes: An Integrated Genomic and Clinicopathologic Study of the Predisposition to Gastric Cancer

* 17-C-0038:
A Phase Ib Open Label, Dose Finding Trial to Evaluate the Safety, Tolerability, and Pharmacokinetics of Avelumab in Combination with M9241 (NHS-IL12) in Subjects with Locally Advanced, Unresectable, or Metastatic Solid Tumors

* 17-C-0034:
A Randomized, Double Blind Phase II Trial of Radiation Therapy Plus Temozolomide and Pembrolizumab with and without HSPPC-96 in Newly Diagnosed Glioblastoma (GBM)

* 17-C-0029:
A Phase II Trial of CUDC-907 in Patients with Metastatic and Locally Advanced Thyroid Cancer

* 17-C-0028:
A Pilot Study of Vincristine Sulfate Liposome Injection (Marqibo ) in Combination with UK ALL R3 Induction Chemotherapy for Children, Adolescents, and Young Adults with Relapse of Acute Lymphoblastic Leukemia

* 17-C-0027:
Long-Term Follow up of Patients Undergoing Hematopoietic Stem Cell Transplantation

* 17-C-0023:
A Phase 1/2 Trial of CV301 In Combination with Nivolumab Versus Nivolumab in Subjects with Previously Treated Non-Small Cell Lung Cancer

* 17-C-0011:
Phase 1 Study of Intraperitoneal Infusion of Autologous Monocytes with Sylatron (Peginterferon alfa-2b) and Actimmune (Interferon gamma-1b) in Women with Recurrent or Refractory Ovarian Cancer, Fallopian Tube Cancer or Primary Peritoneal Cancer

* 17-C-0009:
Phase I Trial of TG02 Plus Dose-Dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of TG02 plus Temozolomide versus Temozolomide alone in Adults with Recurrent Anaplastic Astrocytoma and Glioblastoma

* 17-C-0007:
Phase I/II Study of PROSTVAC in Combination with Nivolumab and / or Ipilimumab in Men with Prostate Cancer

* 17-AT-0075:
Sensory and Opioid Mechanisms of Affective Touch

* 16-N-0170:
Effects of Prism Adaption and rTMS on Brain Connectivity and Visual Representation

* 16-N-0158:
Disease Natural History and Biomarkers of SPG3A, SPG4A and SPG31

* 16-N-0114:
The Effect of Corticosteroids on Inflammation at the Edge of Acute Multiple Sclerosis Plaques: An Investigator-Blinded Study

* 16-N-0072:
A Pilot Study of Adoptive Cellular Immunotherapy for Progressive Multifocal Leukoencephalopathy with Ex Vivo Generated Polyomavirus-Specific T-cells

* 16-N-0064:
Cholinergic Receptor Imaging in Dystonia

* 16-N-0058:
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

* 16-N-0055:
The Pathological Basis of MRI Signal Changes in Multiple Sclerosis: A Longitudinal In Vivo-to-Postmortem Study

* 16-N-0041:
Tumor Related Epilepsy

* 16-N-0031:
An All-Night Functional Magnetic Resonance Imaging Sleep Study With Auditory Stimuli

* 16-M-0093:
PET Imaging of Phosphodiesterase-4 (PDE4) in Brain and Peripheral Organs of Mccune-Albright Syndrome

* 16-I-0165:
Open-Label Long Term Extension Study To Evaluate CDZ173 In Patients With APDS/PASLI (Activated Phosphoinositide 3-Kinase Delta Syndrome/P110 Delta-Activating Mutation Causing Senescent T Cells, Lymphadenopathy And Immunodeficiency)

* 16-I-0147:
VRC 607: A Phase 1, Single Dose Study of the Safety and Virologic Effect of a Human MonoclonalAntibody, VRC-HIVMAB080-00-AB (VRC01LS), with Broad HIV-1 Neutralizing Activity, Administered Intravenously to HIV-Infected Adults.

* 16-I-0126:
Genomic Responses of Human Immune and Non-Immune Cells to Glucocorticoids

* 16-I-0118:
An Exploratory, Open-Label Study of Vedolizumab (anti-alpha4beta7 antibody) in Subjects with HIV Infection Undergoing Analytical Treatment Interruption

* 16-I-0078:
Microbial, Immune, and Metabolic Perturbations by Antibiotics (MIME study)

* 16-I-0053:
A Multicenter Study of the Immunogenicity of Recombinant Vesicular Stomatitis Vaccine for Ebola-Zaire (rVSVdeltaG-ZEBOV GP) for Pre-Exposure Prophylaxis in Individuals at Potential Occupational Risk for Ebola Virus Exposure (PREPARE)

* 16-I-0044:
A Phase 1 Study of CC-11050 in Human Immunodeficiency Virus-1-Infected Adults with Suppressed Plasma Viremia on Antiretroviral Therapy

* 16-I-0039:
Screening of Healthy Volunteers for Investigational Antimalarial Drugs, Malaria Vaccines, and Controlled Human Malaria Challenge

* 16-I-0032:
High Dose Peripheral Blood Stem Cell Transplantation with Post Transplant Cyclophosphamide for Patients with Chronic Granulomatous Disease

* 16-I-0030:
Cardiometabolic Effects of Eplerenone in HIV Infection

* 16-I-0022:
A Randomized Double-Blind, Phase 3 Study Comparing the Efficacy and Safety of High-Titer Versus Low-Titer Anti-Influenza Immune Plasma for the Teatment of Severe Influenza A

* 16-I-0020:
Mepolizumab Long-term Access Program for Subjects who Participated in Study MEA115921 (Placebo-controlled Study of Mepolizumab in the Treatment of Eosinophilic Granulomatosis with Polyangiitis in Subjects Receiving Standard-of-care Therapy)

* 16-I-0018:
VRC 606: A Phase 1, Dose-Escalation Study of the Safety and Pharmacokinetics of a Human Monoclonal Antibody, VRC-HIVMAB080-00-AB (VRC01LS) and VRC-HIVMAB060-00-AB (VRC01), Administered Intravenously or Subcutaneously to Healthy Adults

* 16-I-0008:
Influenza A H3N2 Human Challenge Study in Healthy Adult Volunteers

* 16-I-0002:
A Phase IIa Efficacy, Safety, Tolerability and Pharmacokinetic Study of Encochleated Amphotericin B (CAMB) in Patients with Mucocutaneous (Esophogeal, Oropharyngeal, Vulvovaginal) Candidiasis Who are Refractory or Intolerant to Standard Non-Intravenous T

* 16-HG-0156:
The Natural History, Physiology, Microbiome and Biochemistry Studies of Propionic Acidemia

* 16-HG-0026:
New Technology and Child Health (nTech)

* 16-HG-0017:
Clinical Center Genomics Opportunity Secondary Findings Analysis and Return

* 16-HG-0014:
Phase 1 Dose Finding Trial of ARQ 092 in Children and Adults with Proteus Syndrome

* 16-H-0174:
A Pilot Clinical Trial of COX-2 Inhibition in LAM and TSC

* 16-H-0144:
Impact of Elastin Mediated Vascular Stiffness on End Organs

* 16-H-0132:
CADASIL Disease Discovery

* 16-H-0129:
Study to Evaluate the Effect of Nicotinamide Riboside on Immunity

* 16-H-0123:
Safety and Efficacy of Saracatinib in Subjects with Lymphangioleiomyomatosis (LAM) (SLAM-2)

* 16-H-0074:
Williams Syndrome (WS) and Supravalvular Aortic Stenosis (SVAS) DNA and Tissue Bank

* 16-H-0065:
Screening for Alpha Globin Deletions in Healthy Volunteers

* 16-H-0063:
Williams Syndrome Skin and Vascular Elasticity Study (WS-SAVE Study)

* 16-H-0019:
High Image Matrix CT Reconstruction

* 16-H-0015:
Randomized Phase II Study to Assess the Role of Nivolumab as Single Agent to Eliminate Minimal Residual Disease and Maintain Remission in Acute Myelogenous Leukemia (AML) Patients After Chemotherapy (REMAIN TRIAL)

* 16-EI-0169:
A Pilot Study to Investigate Ustekinumab (STELARA) for the Treatment of Active Sight-Threatening Uveitis

* 16-EI-0159:
A Phase I/II Trial for Intravitreous Treatment of Severe Ocular von Hippel-Lindau Disease Using a Combination of the PDGF Antagonist E10030 and the VEGF Antagonist Ranibizumab

* 16-EI-0134:
Studies of the Natural History, Pathogenesis and Outcome of Ocular Disorders

* 16-EI-0104:
Clinical and Molecular Studies in Families with Inherited Eye Disease

* 16-EI-0102:
PeriOcular and Intravitreal Corticosteroids for Uveitic Macular Edema (POINT) Trial

* 16-EI-0090:
Natural History of Spinocerebellar Ataxia Type 7 (SCA7)

* 16-EI-0046:
Uveitis/Intraocular Inflammatory Disease Biobank (iBank)

* 16-EI-0024:
Rod and Cone Mediated Function in Retinal Disease

* 16-E-0157:
CaREFREE Study (Calorie Restriction, Environment and Fitness: Reproductive Effects Evaluation Study)

* 16-E-0006:
Investigating the Impact of Obesity on Pubertal Development in Girls

* 16-DK-0173:
MEASuRE: Metreleptin Effectiveness and Safety Registry

* 16-DK-0143:
Idiosyncratic Liver Injury Associated with Drugs (ILIAD): A Retrospective Study

* 16-DK-0075:
Study Glomerulopathy

* 16-DK-0068:
The Molecular, Cellular, and Genetic Characterization of Human Adipose Tissue and its Role in Metabolism

* 16-DK-0038:
A Randomized, Double Blind, Placebo-Controlled Study to Assess Efficacy, Safety and Tolerability of ISIS 304801 in Patients with Partial Lipodystrophy with an Open-Label Extension

* 16-DK-0036:
A Phase 1 Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ManNAc in Subjects with Primary Podocyte Diseases

* 16-D-0040:
Natural History of Craniofacial Anomalies and Developmental Growth Variants

* 16-CH-0164:
A Phase III Extension Study of Efficacy, Safety and Tolerability of Chronocort (Registered Trademark) in the Treatment of Congenital Adrenal Hyperplasia

* 16-CH-0150:
A Phase 2, Multicenter Study of ATR-101 for the Treatment of Congenital Adrenal Hyperplasia

* 16-CH-0125:
Evaluation of Adults with Endocrine-Related Conditions

* 16-CH-0113:
Evaluation of Children with Endocrine and Metabolic-Related Conditions

* 16-CH-0103:
Studies of Pediatric Patients With Metabolic or Other Genetic Disorders

* 16-CH-0057:
A Phase III Study of Efficacy, Safety and Tolerability of Chronocort Compared with Standard Glucocorticoid Replacement Therapy in the Treatment of Congenital Adrenal Hyperplasia

* 16-CH-0016:
A Phase 2b/3 Prospective, Randomized, Double-Blind, Sham-Controlled Trial of VTS270 (2-hydroxypropyl-B-cyclodextrin) in Subjects with Neurologic Manifestations of Niemann-Pick Type C1 (NPC1) Disease

* 16-CC-0162:
Longitudinal Changes in the Oral and Gut Microbiome of Individuals with Alcohol Dependence

* 16-CC-0149:
Dopamine and Motor Learning in Cerebral Palsy

* 16-CC-0124:
Study of Zika Virus and Related Arbovirus Infections in Deferred Blood Donors

* 16-CC-0089:
CT COMPARE: CT COronary Angiography to Measure PlAque REduction

* 16-CC-0049:
A Phase II Study Using LC Bead LUMI Radio-Opaque Embolic Beads to Detect and Characterize the Vascularity of Hepatic Tumors During Treatment with Transarterial Embolization (TAE) Alone or Combined with Thermal Ablation

* 16-CC-0001:
Evaluation of MiSeq for Microbial Identification in Specimens

* 16-C-0172:
Phase II Trial of Nivolumab for HTLV-Associated Adult T Cell Leukemia/Lymphoma

* 16-C-0171:
Phase I/II Study of Lenalidomide Combined with Modified DA-EPOCH and Rituximab (EPOCH-R(2)) In Primary Effusion Lymphoma or KSHV-Associated Large Cell Lymphoma

* 16-C-0160:
A Phase II Study of Avelumab in Subjects with Recurrent Respiratory Papillomatosis

* 16-C-0154:
A Phase I Trial of T Cell Receptor Gene Therapy Targeting HPV-16 E7 with or without PD-1 Blockade for HPV-Associated Cancers

* 16-C-0153:
Brain Interstitium Temozolomide Concentration Pre and Post Regadenoson Administration

* 16-C-0151:
Evaluation of the Natural History of and Specimen Banking for Patients with Tumors of the Central Nervous System

* 16-C-0138:
Collection of Peripheral Blood Mononuclear Cells (PBMCs) from Healthy Subjects for the Expansion of T Cells for Adoptive Cell Therapy

* 16-C-0135:
A Pilot Study of Combined Immune Checkpoint Inhibition in combination with Ablative Therapies in Subjects with Hepatocellular Carcinoma (HCC) or Biliary Tract Carcinomas (BTC)

* 16-C-0131:
Phase I/II Study Administering Peripheral Blood Lymphocytes Transduced with a CD70-Binding Chimeric Antigen Receptor to Patients with CD70 Expressing Cancers

* 16-C-0128:
A Phase Ib/II Study of Mesothelin-Targeted Immunotoxin LMB-100 Alone or in Combination with Nab-Paclitaxel in Participants with Previously Treated Metastatic and/ or Locally Advanced Pancreatic Ductal Adenocarcinoma and Mesothelin Expressing Solid Tumors

* 16-C-0127:
A Phase I Study of the Reduced Immunogenicity Mesothelin-Targeted Immunotoxin LMB-100 in Patients with Malignant Mesothelioma

* 16-C-0121:
A Pilot Clinical Trial of Genomic Based Assignment of Therapy in Advanced Urothelial Carcinoma

* 16-C-0109:
Phase 1 Trial of the Combination of the Heat Shock Protein-90 (HSP90) Inhibitor Onalespib (AT13387) and the Cyclin-Dependent Kinase (CDK) Inhibitor AT7519 in Patients with Advanced Solid Tumors

* 16-C-0107:
A Phase I/II Trial of CRLX101, a Nanoparticle Camptothecin with Olaparib in Patients with Relapsed/Refractory Small Cell Lung Cancer

* 16-C-0099:
An Open Label Phase Ib Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Immunogenicity and Maximum Tolerated Dose of Anetumab Ravtansine in Combination with Pemetrexed 500 mg/m(2) and Cisplatin 75 mg/m(2) in Subjects with Mes

* 16-C-0094:
A Phase 1/2 Study of Baricitinib, a JAK1/2 Inhibitor, in Chronic Graft-Versus-Host Disease (cGVHD) after Allogeneic Hematopoietic Stem Cell Transplantation (SCT)

* 16-C-0092:
A Pilot Study of Local Ablative Therapy for Treatment of Oligoprogressive, EGFR-mutated, Non-Small Cell Lung Cancer (NSCLC) After Treatment with Osimertinib (AZD9291, Tagrisso)

* 16-C-0091:
Long-Term Follow-up of Subjects Treated with bb2121

* 16-C-0088:
A Randomized Phase II/III Study of the Combination of Cediranib and Olaparib Compared to Cediranib or Olaparib Alone, or Standard of Care Chemotherapy in Women with Recurrent Platinum-Resistant or -Refractory Ovarian, Fallopian Tube, or Primary Peritonea

* 16-C-0087:
Phase I Study of Veliparib (ABT-888), an Oral PARP Inhibitor, and VX-970, an ATR Inhibitor, in Combination with Cisplatin in Patients with Refractory Solid Tumors

* 16-C-0086:
An Open Label Phase 1B/2 Trial of TRC 105 and Sorafenib in Patients with Hepatocellular Carcinoma (HCC)

* 16-C-0081:
A Phase I Dose Escalation Trial of Re-Irradiation in Good Prognosis Recurrent Glioblastoma

* 16-C-0079:
A Phase 1 Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of Escalating Doses of a Vaccine-Based Immunotherapy Regimen (VBIR) for Prostate Cancer (PF-06753512)

* 16-C-0076:
Prospective Screening for Patient Specific Genotypes and Phenotypes that Influence Drug Dosing and Trial Selection in Cancer Patients

* 16-C-0073:
A Phase 2 Study of Olaparib and Cediranib for the Treatment of Recurrent Ovarian Cancer

* 16-C-0066:
Phase I Study of Pembrolizumab in Patients with Human Immunodeficiency Virus (HIV) and Relapsed/Refractory or Disseminated Malignant Neoplasm

* 16-C-0062:
A Phase I Study Of Subcutaneous Recombinant Human IL-15 (S.C.rhIL-15) and Alemtuzumab for Patients with Refractory or Relapsed Chronic and Acute Adult T-Cell Leukemia (ATL)

* 16-C-0061:
Biospecimen Procurement for Experimental Transplantation and Immunology Branch Immunotherapy Protocols

* 16-C-0060:
A Phase 1b/2 Study of AZD9668, an Oral Neutrophil Elastase Inhibitor, in Bronchiolitis Obliterans Syndrome after Allogeneic Hematopoietic Stem Cell Transplantation

* 16-C-0054:
T Cells Expressing a Fully-Human Anti-CD19 Chimeric Antigen Receptor for Treating B-cell Malignancies

* 16-C-0048:
Docetaxel and Prostvac for Metastatic Castration Sensitive Prostate Cancer

* 16-C-0047:
A Phase 1 Trial of Pomalidomide in Combination with Liposomal Doxorubicin in Patients with Advanced or Refractory Kaposi Sarcoma

* 16-C-0043:
Phase II Trial of the MEK1/2 Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate in Adults with Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas

* 16-C-0035:
Prostvac in Patients with Biochemically Recurrent Prostate Cancer

* 16-C-0027:
A Prospective Randomized and Phase 2 Trial for Metastatic Melanoma using Adoptive Cell Therapy with Tumor Infiltrating Lymphocytes Plus IL-2 either Alone or Following the Administration of Pembrolizumab

* 16-C-0025:
A Phase 1 Study of bb2121 in BCMA-Expressing Multiple Myeloma

* 16-C-0013:
An Open-Label, Phase 1 Study of the Safety and Immunogenicity of JNJ-64041757, a Live Attenuated Listeria Monocytogenes Immunotherapy, in Subjects with Non-Small Cell Lung Cancer

* 16-C-0011:
A Phase I-II Trial of Everolimus and Sorafenib in Patients with Recurrent High-Grade Gliomas

* 16-C-0010:
Care of the Prostate Cancer Patient and Prospective Procurement of Prostate Cancer Tissue

* 16-C-0009:
Phase II Trial of Carboplatin and Bevacizumab for the Treatment of Recurrent Low-Grade and Anaplastic Supratentorial, Infratentorial and Spinal Cord Ependymoma in Adults: A Multi-Center Trial

* 16-C-0003:
Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies

* 16-AT-0136:
Effects of External Ear Stimulation on Pain Perception and Mood

* 16-AT-0077:
Clinical and Scientific Assessment of Pain and Painful Disorders

* 16-AA-0080:
A Novel Compound for Alcoholism Treatment: a Translational Strategy - Part II

* 16-AA-0059:
Characterization of Brain Amyloid-beta (A-beta) Retention During Wakefulness And Following Emergence From Sleep In Healthy Subjects

* 16-AA-0037:
Effect of Opioid Receptor Modulation on Alcohol Self-Administration and Neural Response to Alcohol Cues in Heavy Drinkers: Role of OPRM1 Gene Variation

* 15-NR-0085:
Effects of Tart Cherry and Aroniaberry Supplementation on Endothelial Function and Cardiovascular Measures in Healthy Older Adults:Interactions with Genotype and Proteome

* 15-NR-0072:
Antioxidant Therapy in RYR1-Related Congenital Myopathy

* 15-NR-0037:
Effect of Ketamine on Fatigue Following Cancer Therapy

* 15-N-0183:
Anakinra, a Recombinant Human IL-1 Receptor Antagonist for Neuroinflammation in HIV-1 Infection

* 15-N-0181:
International Nested, Double Blind Placebo-Controlled Clinical Trial of Corticosteroids in HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP)

* 15-N-0167:
Propensity to Develop Plasticity in the Parieto- & Cerebello-Motor Networks in Dystonia from the Perspective of Abnormal High-Order Motor Processing

* 15-N-0158:
Thematic Studies of Multiple Sclerosis and Related Diseases

* 15-N-0156:
In Vivo Characterization of Inflammation with Ferumoxytol, an Ultrasmall Superparamagnetic Iron Oxide Nanoparticle, on 7 Tesla Magnetic Resonance Imaging

* 15-N-0126:
HERV-K Suppression using Antiretroviral Therapy in Volunteers with Amyotrophic Lateral Sclerosis (ALS)

* 15-N-0125:
Natural History Study of Inflammatory and Infectious Diseases of the Nervous System

* 15-N-0117:
Phase I Study of Oral Guanabenz for Multiple Sclerosis

* 15-N-0081:
An Investigator-Initiated, Prospective, Multi-Center, Controlled Feasibility Study of Direct Brain Recording and Stimulation for Memory Enhancement

* 15-N-0073:
A Phase I Study of Intrathecal Administration of scAAV9/JeT-GAN for the Treatment of Giant Axonal Neuropathy

* 15-N-0066:
Influence on Plasticity of Brain Temperature

* 15-N-0035:
Comparison of Electrophysiologic and Ultrasound Guidance for Onabotulinum Toxin A Injections in Focal Upper Extremity Dystonia and Spasticity

* 15-N-0018:
Congenital Muscular Dystrophy Ascending Multiple Dose Cohort Study analyzing Pharmacokinetics at three dose Levels In Children and Adolescents with Assessment of Safety and Tolerability of Omigapil

* 15-M-0188:
The Neurobiology of Suicide

* 15-M-0182:
Psychological Treatments for Youth with Severe Irritability.

* 15-M-0151:
An Investigation of the Antidepressant Effects of the Glycine Receptor Antagonist AV 101 (4-chlorokynurenine) in Major Depressive Disorder

* 15-M-0139:
Mapping the Genotype, Phenotype, and Natural History of Phelan McDermid Syndrome

* 15-M-0114:
fMRI Spatial Context and Fear Conditioning

* 15-M-0109:
Checking out Checking In: The Development and Validation of an Electronic Screening Tool for Pediatric Psychosocial Distress

* 15-I-0187:
Sputum Pharmacokinetics of TB Drugs and Bacterial Drug Resistance

* 15-I-0162:
Natural History and Genetics of Food Allergy and Related Conditions

* 15-I-0161:
A Double-blind, Placebo-controlled, Crossover Study of Magnesium Supplementation in Patients with XMEN Syndrome

* 15-I-0154:
Long-Term Observation of Hemagglutinin and Neuraminidase Inhibition Antibody Titers After Influenza Challenge

* 15-I-0135:
An Open-Label, Non-Randomized, Within-Patient Dose-Finding Study Followed by a Randomized, Double-Blind Placebo Controlled Study with Extension to Assess the Safety and Efficacy of CDZ173 in Patients with APDS/PASLI (Activated Phosphoinositide 3-kinase D

* 15-I-0131:
Xenodiagnosis after Antibiotic Treatment for Lyme Disease - Phase II Study

* 15-I-0122:
Partnership for Research on Ebola Virus (PREVAIL) III: Ebola Natural History Study

* 15-I-0094:
A Phase 1a Open-Label Study to Assess the Safety and Pharmacokinetics of a Single ZMappTM Administration in Healthy Adult Volunteers

* 15-I-0089:
Anti-Influenza Hyperimmune Intravenous Immunoglobulin Clinical Outcome Study (INSIGHT 006: FLU-IVIG)

* 15-I-0069:
Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study in Healthy Volunteers to Evaluate the Efficacy and Safety of CR6261 in an H1N1 Influenza Healthy Human Challenge Model

* 15-I-0056:
Collection of Plasma from Subjects that Recovered From or Were Vaccinated To Emerging Infectious Diseases

* 15-I-0036:
Tesamorelin Effects on Liver Fat and Histology in HIV: A Collaborative UO1 Grant

* 15-I-0008:
A Phase I/II, Non Randomized, Multicenter, Open-Label Study of G1XCGD (Lentiviral Vector Transduced CD34+ Cells) in Patient with Xlinked Chronic Granulomatous Disease (CGD)

* 15-HG-0130:
Clinical and Genetic Evaluation of Patients with Undiagnosed Disorders Through the Undiagnosed Diseases Network

* 15-HG-0120:
Nonrandomized Open Label Pilot Study of Sirolimus Therapy for Segmental Overgrowth Caused by Somatic PI3K Activation

* 15-HG-0049:
Maternal Inborn Errors of Metabolism in Pregnancy: A Pregnancy Registry Protocol

* 15-H-0190:
Human Biospecimen Procurement Protocol: Biorepository to Support Translational Research to Identify Disease Mechanism(s)

* 15-H-0176:
A Pilot Study of Biomarkers for Personalized Early Assessment of Response During Salvage Chemotherapy in Patients with Relapsed Orrefractory Acute Myeloid Leukemia

* 15-H-0173:
Comparison of EPA and DHA-Rich Fish Oils on Lipoprotein Metabolism In Adults

* 15-H-0172:
A Pilot Phase II Study Using Ibrutinib and Short-Course Fludarabine in Previously Untreated Patients with Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)

* 15-H-0155:
Hereditary Parkinson's Disease Natural History Protocol

* 15-H-0136:
Pilot Study to Evaluate the Effect of Fasting on the Asthma Inflammasome

* 15-H-0088:
A Pilot Study of Early Treatment of Acute Graft Versus Host Disease with Bone Marrow- Derived Mesenchymal Stem Cells and Corticosteroids: Correlation of Disease Severity and Response with Biomarkers

* 15-H-0042:
Evaluation of the Effects of Niacin Therapy on Lipoprotein Composition and Function

* 15-H-0026:
Prospective International Study of Coronary Subtraction Using 320 Row-Detector CT

* 15-H-0024:
Genes Involved in Lipid Disorders

* 15-H-0017:
Characterization of Apolipoprotein A-I Pathways in Idiopathic Pulmonary Fibrosis

* 15-H-0016:
A Phase II Study Using ACP-196 in Patients with Relapsed/Refractory and Treatment Naive Deletion 17p CLL/SLL: Pharmacodynamic Assessment of BTK Inhibition and Anti-Tumor Response

* 15-H-0015:
Complement Inhibition using Eculizumab to Overcome Platelet Transfusion Refractoriness in Patients with Severe Thrombocytopenia

* 15-EI-0202:
Evaluation of Oral Minocycline in the Treatment of Geographic Atrophy Associated with Age-Related Macular Degeneration

* 15-EI-0128:
The Genetics of Inherited Eye Disease

* 15-EI-0052:
Pilot Phase I/II Study of the Evaluation of Interferon Gamma-1b Administered Topically for Macular Edema/Intraretinal Schisis Cysts in Rod-Cone Dystrophy (RCD) and Enhanced S-Cone Syndrome (ESCS)

* 15-EI-0041:
Patient Expectations When Enrolling in a Phase I/II RS1 Ocular Gene Transfer Clinical Trial

* 15-EI-0038:
A Phase I/IIa Study of RS1 Ocular Gene Transfer for X-linked Retinoschisis

* 15-EI-0020:
Adaptive Optics Retinal Imaging

* 15-E-0058:
Natural History of Asthma with Longitudinal Environmental Sampling

* 15-DK-0174:
Dynamic Post-Prandial Metabolism in Patients with Non-Alcoholic Fatty Liver Disease

* 15-DK-0143:
Investigation of Viral Kinetics, Interferon Stimulated Genes (ISGs) and mirRNA Among Subjects Infected with Different Hepatitis C Virus Genotypes During Therapy with Sofosbuvir and GS-5816

* 15-DK-0119:
Thyroid Hormone to Induce Non-Insulin Mediated Glucose Disposal in Patients with Insulin Receptor Mutations

* 15-DK-0108:
Natural History of Noncirrhotic Portal Hypertension

* 15-DK-0082:
Mechanisms Associated with Favorable Response to Peginterferon-Alpha Add-on Therapy Following Long-term Nucleos(t)ide Analogue Treatment in Patients with Chronic Hepatitis B

* 15-DK-0080:
Palmitate Breath Test to Assess Fatty Acid Oxidation in Non Alcoholic Fatty Liver Disease

* 15-DK-0079:
Observational Study of Hepatitis B Virus (HBV) in Patients Coinfected with Human Immunodeficiency Virus (HIV)

* 15-DK-0003:
Compassionate Use of Metreleptin in Previously-Treated Patients with Generalized Lipodystrophy

* 15-DK-0002:
Compassionate Use of Metreleptin in Previously-Treated Patients with Partial Lipodystrophy

* 15-D-0129:
Open-Label, Dose-Escalation Study Evaluating the Safety of a Single Administration of an Adeno-Associated Virus Vector Encoding Human Aquaporin-1 to One Parotid Salivary Gland in Individuals with Irradiation-Induced Parotid Salivary Hypofunction

* 15-D-0051:
Characterization of Diseases with Salivary Gland Involvement

* 15-CH-0096:
Children's Growth and Behavior Study

* 15-CH-0022:
Genetic Causes of Growth Disorders

* 15-CC-0193:
A Pilot Study to Assess Safety, Tolerability, and Efficacy of Sofosbuvir and Ledipasvir for Hepatitis C Treatment in HIV/HCV Coinfected Subjects Pre or Post Liver Transplant

* 15-CC-0164:
Effect of Exercise Training on Physical, Cognitive and Behavioral Function in Patients with Traumatic Brain Injury

* 15-CC-0137:
A Pilot Study of an Integrated Imaging Strategy to Phenotype Progression of Liver Tumors During and After Chemoembolization

* 15-CC-0103:
Evaluation of Neurocognitive Driving Rehabilitation in Virtual Environments (NeuroDRIVE) as an Adjunctive Intervention for Traumatic Brain Injury

* 15-CC-0091:
Pulmonary Effects of Bronchial Segmental Endotoxin Instillation in Humans

* 15-C-0205:
Phase II Randomized, Placebo-Controlled Trial of PROSTVAC (PSA-TRICOM) in Patients with Clinically Localized Prostate Cancer Undergoing Active Surveillance

* 15-C-0204:
Clinical and Laboratory Analysis of Familial Cancer

* 15-C-0200:
Molecular Analysis for Therapy Choice (MATCH) (EAY131)

* 15-C-0195:
Development and Validation of Patient Reported Outcome (PRO) Measures for Individuals with Neurofibromatosis 1 (NF1) and Plexiform Neurofibromas (PNs)

* 15-C-0191:
A Phase 1 Study of the Safety, Pharmacokinetics, and Pharmacodynamics of Escalating Oral Doses of the Glutaminase Inhibitor CB-839, as a Single Agent and in Combination with Standard Chemotherapy in Patients with Advanced and/or Treatment-Refractory Soli

* 15-C-0184:
A Phase 1/2 Proof-of-Concept Study of the Combination of ACP-196 and ACP-319 in Subjects with B-Cell Malignancies

* 15-C-0179:
A Phase I, Open-Label, Multiple-Ascending Dose Trial to Investigate the Safety, Tolerability, Pharmacokinetics, Biological and Clinical Activity of MSB0011359C in Subjects with Metastatic or Locally Advanced Solid Tumors with Expansion to Selected Indica

* 15-C-0166:
Phase 2 Study of Everolimus Therapy in Patients with Birt-Hogg-Dube Syndrome (BHD)-Associated Kidney Cancer or Sporadic Chromophobe Renal Cancer

* 15-C-0160:
A Phase I Study of Cabozantinib Plus Nivolumab (CaboNivo) Alone or in Combination with Ipilimumab (CaboNivoIpi) in Patients with Advanced/Metastatic Urothelial Carcinoma and other Genitourinary Tumors

* 15-C-0157:
Phase I/II Trial of Vandetanib in Combination with Metformin in Subjects with HLRCC or SDH-Associated Kidney Cancer or Sporadic Papillary Renal Cell Carcinoma

* 15-C-0150:
A Phase I/II Trial of Topotecan with VX970, an ATR Kinase Inhibitor in Small Cell Cancers

* 15-C-0146:
Exceptional Responders Pilot Study: Molecular Profiling of Tumors from Cancer Patients who are Exceptional Responders

* 15-C-0145:
Phase I/II Study of the Anti-Programmed Death Ligand-1 Antibody MEDI4736 in Combination with Olaparib and/or Cediranib for Advanced Solid Tumors and Advanced or Recurrent Ovarian, Triple Negative Breast, Lung, Prostate and Colorectal Cancers

* 15-C-0144:
Studies of Dermatologic Diseases-Biospecimen Acquisition Protocol

* 15-C-0142:
Acceptance and Commitment Training for Adolescents and Young Adults with Neurofibromatosis Type 1, Plexiform Neurofibromas, and Chronic Pain: A Phase III Clinical Trial

* 15-C-0141:
Gene Therapy Follow up Protocol for Subjects Previously Enrolled in NCI Experimental Transplantation and Immunology Branch Studies

* 15-C-0138:
Phase I Study of Ipilimumab, Nivolumab, and the Combination in Patients with Newly Diagnosed Glioblastoma

* 15-C-0124:
Neoadjuvant Androgen Deprivation and Enzalutamide: Using Multiparametric MRI to Evaluate Intraprostatic Tumor Responses and Androgen Resistance Patterns in Newly Diagnosed Prostate Cancer

* 15-C-0118:
A Randomized, Double-Blind, Phase 2 Trial of GI-6301 (Yeast-Brachyury Vaccine) Versus Placebo in Combination with Standard of Care Definitive Radiotherapy in Locally Advanced, Unresectable, Chordoma

* 15-C-0116:
Phase I Trial of 4'-thio-2'-deoxycytidine (TdCyd) in Patients With Advanced Solid Tumors

* 15-C-0110:
A Phase I/Ib Study of Subcutaneous Recombinant Human NIZ985 ((hetIL-15) (IL15/sIL-15Ra)) alone and in combination with PDR001 in Adults with Metastatic Cancers

* 15-C-0105:
Randomized Controlled Trial of Total Thyroidectomy with and without Prophylactic Central Neck Lymph Node Dissection in Patients with Low-risk Papillary Thyroid Cancer

* 15-C-0101:
Phase I/II Study of Nivolumab (IND#124729) in Children, Adolescents, and Young Adults with Recurrent or Refractory Solid Tumors as a Single Agent and in Combination with Ipilimumab

* 15-C-0095:
Expanded Access (Compassionate Use) Treatment Protocol with Rindopepimut (CDX-110)

* 15-C-0093:
Phase I/II Trial of PLX3397 in Children and Young Adults with Refractory Leukemias and Refractory Solid Tumors Including Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PN)

* 15-C-0087:
Care of the Urothelial Cancer Patient and Prospective Collection of Biospecimens from Healthy Volunteers and Urothelial Cancer Patients

* 15-C-0086:
Phase I Trial of the Combination of Nilotinib and Paclitaxel in Adults with Refractory Solid Tumors

* 15-C-0078:
Safety and Feasibility of Stem Cell Gene Transfer Following R-EPOCH for Non-Hodgkin Lymphoma in AIDS Patients Using Peripheral Blood Stem/Progenitor Cells Treated with a Lentivirus Vector-Encoding Multiple Anti-HIV RNAs

* 15-C-0076:
A Pilot Study of Long Term TARP Vaccination Using A Multi-Epitope TARP Peptide Autologous Dendritic Cell Vaccine in Previously Vaccinated Men on NCI 09-C-0139

* 15-C-0075:
A Randomized, Placebo-Controlled Phase II Study of Multi-Epitope TARP Peptide Autologous Dendritic Cell Vaccination in Men with Stage D0 Prostate Cancer

* 15-C-0067:
A Phase I/II Open Label, Dose Escalation Study of Palifermin (Kepivance) in Persons Undergoing Unrelated Donor Allogeneic Hematopoietic Cell Transplantation

* 15-C-0040:
A Phase II Trial of Mutation-Targeted Therapy with Sunitinib or Everolimus in Patients with Advanced Low-or Intermediate Grade Neuroendocrine Tumors of the Gastrointestinal Tract and Pancreas With or Without Cytoreductive Surgery

* 15-C-0029:
Phase I Dose Escalation Study of Anti-CD22 Chimeric Receptor T Cells in Pediatric and Young Adults with Recurrent or Refractory CD22-expressing B Cell Malignancies

* 15-C-0028:
Follow-Up Evaluation for Gene-Therapy Related Delayed Adverse Events After Participation in Pediatric Oncology Branch Clinical Trials

* 15-C-0027:
A Pilot Study of Immune Checkpoint Inhibition (Durvalumab with or without Tremelimumab) in Combination with Radiation Therapy in Patients with Unresectable Pancreatic Cancer

* 15-C-0019:
The Impact of Ras/MAPK Signaling Pathway-Targeted Therapies on Neurocognitive Functioning in Individuals with NF1

* 15-C-0004:
Long-Term Follow-Up of Subjects Who have Participated in Aduro-Sponsored Protocols

* 15-AT-0132:
Neural and Psychological Mechanisms of Pain Perception

* 15-AT-0048:
Psychophysical Correlates of Pain Reduction by Topical Analgesic Compounds

* 15-AR-0185:
Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Systemic Lupus Erythematosus; a Phase Ib Clinical Trial and Associated Mechanistic Studies

* 15-AR-0165:
Study of the Natural History, Pathogenesis and Outcome of Melorheostosis - a Rare Osteosclerotic Disease

* 15-AR-0060:
The Role of PPAR-Gamma Agonists in Immunomodulation and Vascular Prevention in SLE (PPAR-SLE)

* 15-AG-0123:
Intermittent Calorie Restriction, Insulin Resistance, and Biomarkers of Brain Function

* 15-AG-0063:
The Genetic and Epigenetic Signatures of Translational Aging Laboratory Testing (GESTALT)

* 15-AA-0203:
Cross-Sectional and Longitudinal Study of Structural Imaging

* 15-AA-0186:
Development of Neuroimaging Methods to Assess the Neurobiology of Addiction

* 15-AA-0127:
(Epi)genetic Modulators of Fear Extinction in Alcohol Dependence

* 15-AA-0031:
Human Brain Mapping of the Apparent Diffusion Coefficient (ADC) During Sleep and Wakefulness

* 14-NR-0118:
The Calibration and Validation of the PROMIS and Neuro-QOL Questionnaires in Cerebral Palsy and Congenital Muscular Dystrophy

* 14-NR-0034:
Effects of Dietary Blackcurrant Extract and PCSO-524 (PernaCanaliculus Supercritical Oil) on Endothelial Function and Biomarkers of Vascular Health

* 14-NR-0032:
An Investigation of the Biological and Neuronal Mechanisms of Post-Traumatic Stress Disorder, Depression and Post-Concussive Syndrome Onset Following a Traumatic Brain Injury

* 14-NR-0023:
Development of a Proxy Motor Outcome Measure in Young Children with Neuromuscular Disease

* 14-N-0174:
Effect of Administration of Recombinant Erythropoietin on Numbers of Circulating Endothelial Progenitor Cells in Patients with Persistent Symptoms During the Subacute Period After TBI

* 14-N-0122:
Clinical Autonomic Disorders: A Training Protocol

* 14-N-0099:
Evaluation of Hepatic Function in Patients with Spinal and Bulbar Muscular Atrophy

* 14-N-0086:
Deep Brain Stimulation Therapy in Movement Disorders

* 14-N-0083:
Neural Basis of Decision Making Deficits in Traumatic Brain Injury

* 14-N-0070:
Depotentiation in Focal Hand Dystonia Patients

* 14-N-0069:
Real-time fMRI Neurofeedback for Motor Rehabilitation

* 14-N-0067:
Pilot Study of the Effect of Vorinostat on Nervous System Hemangioblastomas In Von Hippel-Lindau Disease

* 14-N-0061:
Noninvasive Pre-surgical Evaluation of Patients with Focal Epilepsy and Establishment of a Normative Imaging Database

* 14-N-0033:
Phase 2 Clinical Trial of SGS-742 Therapy in Succinic Semialdehyde Dehydrogenase Deficiency

* 14-N-0002:
Functional Brain Imaging in Healthy Volunteers to Study Cognitive Functions

* 14-M-0109:
Ask Suicide-Screening Questions to Everyone in Medical Settings (asQ'em): Development of a Suicide Risk Screening Instrument for Adult Medical Inpatients

* 14-M-0085:
The Neurophysiological Effects of Intravenous Alcohol as Potential Biomarkers of Ketamine's Rapid Antidepressant Effects in Major Depressive Disorder

* 14-I-0206:
Novel Genetic Disorders of the Immune System

* 14-I-0199:
Human Immunity Against Staphylococcus Aureus Skin Infection

* 14-I-0194:
Screening of Volunteers for Clinical Trials of Investigational or Licensed Vaccines or Antiviral Products

* 14-I-0191:
NACC 002: A Multicenter Prospective Natural History Study of Patients Presenting with Neurocysticercosis in North America

* 14-I-0185:
A Phase III Double-Blind Randomized Crossover Study of Plerixafor Versus G-CSF in the Treatment of Patients with WHIM Syndrome.

* 14-I-0178:
Longitudinal Study of Immune Responses to Mycobacterium Tuberculosis (Mtb) in Subjects with Latent Tuberculosis (TB) Infection(LTBI) With or Without Concomitant Helminth Infection

* 14-I-0153:
An Open-Label Phase I/II Pilot Study to Assess the Safety/Tolerability and Efficacy of Ustekinumab for Symptomatic Gastrointestinal Inflammation Associated with Common Variable Immunodeficiency

* 14-I-0146:
The Pathogenesis and Genetics of Disseminated or Refractory Coccidiodomycosis

* 14-I-0124:
PET Imaging and Lymph Node Assessment of IRIS in Persons With AIDS

* 14-I-0091:
Analysis of Patients Treated for Chronic Granulomatous Disease Since January 1, 1995

* 14-I-0089:
A Retrospective and Cross-Sectional Analysis of Patients Treated for Severe Combined Immunodeficiency (SCID) Since January 1, 1968

* 14-I-0081:
A Phase 2a Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Subcutaneous Benralizumab (MEDI-563) in Reducing Eosinophilia in Subjects with Hypereosinophilic Syndrome (HES)

* 14-I-0072:
A Prospective Natural History Study of Diagnosis, Treatment and Outcomes of Children with SCID Disorders

* 14-I-0039:
Elite Controller and ART-Treated HIV+ Statin Versus ASA Treatment Intervention Study

* 14-I-0020:
Hematopoietic Stem Cell Mobilization in Idiopathic CD4 Lymphocytopenia Patients and Healthy Controls for the Study of T Cell Maturation and Trafficking in Murine Models

* 14-I-0011:
Phase I Study of Safety and Immunogenicity of Ad4-HIV Vaccine Vectors in Healthy Volunteers

* 14-I-0009:
Characterization and Management of Patients with HIV-1 Infection Who Experience Virologic Failure Despite Combination Antiretroviral Therapy

* 14-HG-0125:
Insights into Microbiome and Environmental Contributions to Sickle Cell Disease and Leg Ulcers

* 14-HG-0071:
Clinical and Basic Investigations into Known and Suspected Congenital Disorders of Glycosylation

* 14-HG-0055:
Study on Moebius Syndrome and Other Congenital Facial Weakness Disorders

* 14-HG-0048:
GENE-FORECASTSM: Genomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African-Americans Study

* 14-H-0188:
Prospective Evaluation of Next Generation CT Reconstruction

* 14-H-0182:
Phase I/II Trial of Early Infusion of Rapidly-generated Multivirus Specific T cells (MVST) to Prevent Post Transplant Viral Infections

* 14-H-0180:
Ultra Low Dose IL-2 Therapy as GVHD Prophylaxis in Haploidentical Allogeneic Stem Cell Transplantation

* 14-H-0172:
Assessment of Computerized Algorithm-Based Hydroxyurea Dosing on Fetal Hemoglobin Response, Acute Complications, and Organ Function in Subjects with Sickle Cell Disease

* 14-H-0155:
A Phase 1 Study Evaluating Gene Therapy by Transplantation of Autologous CD34+ Stem Cells Transduced Ex Vivo with the LentiGlobinA BB305 Lentiviral Vector in Subjects with Severe Sickle Cell Disease

* 14-H-0127:
Characterization of the Pathogenesis of Primary and Secondary Lymphatic Disorders

* 14-H-0077:
Nonmyeloablative Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation For Sickle Cell Disease and Beta-Thalassemia in Individuals With Higher Risk of Transplant Failure

* 14-H-0049:
Clinical Outcomes and Molecular Phenotypes in Smokers with Parenchymal Lung Disease

* 14-EI-0171:
The Focal Electro-Oculogram in Macular Disease

* 14-EI-0064:
Whole Exome and Whole Genome Sequencing for Genotyping of Inherited and Congenital Eye Conditions

* 14-E-0204:
A Pharmacokinetic Study to Assess and Compare the Drug Interaction Risk of the Grapefruit Juice and Dietary Supplements Known to Inhibit CYP3A Enzyme Activity

* 14-DK-0195:
Acute Effects of Canagliflozin, a Sodium Glucose Co-Transporter 2 (SGLT2) Inhibitor on Bone Metabolism in Healthy Volunteers

* 14-DK-0060:
Famine from Feast: Linking Vitamin C, Red Blood Cell Fragility, and Diabetes

* 14-CH-0139:
Deep Reading as a Contemplative Practice for Women with Primary Ovarian Insufficiency: An Exporatory Pilot Study.

* 14-CH-0119:
Pilot Study of the Effects of Colchicine in Non-Diabetic Adults with Metabolic Syndrome

* 14-CH-0106:
Clinical Biomarkers in Alpha-Mannosidosis

* 14-CH-0028:
Evaluation of 68Ga-DOTATATE PET/CT, Octreotide and F-DOPA PET Imaging in Patients with Ectopic Cushing Syndrome

* 14-CC-0201:
A Randomized Controlled Trial to Determine the Effectiveness of a Stress Reduction Intervention in Caregivers of Allogeneic Hematopoietic Stem Cell Transplant (HSCT) Recipients

* 14-CC-0179:
Losartan to Reduce Inflammation and Fibrosis Endpoints in HIV (LIFE-HIV) Trial

* 14-CC-0158:
Imaging Techniques in CT: Technical Development

* 14-CC-0143:
Sleep Disturbance and Relapse in Individuals with Alcohol Dependence: An Exploratory Mixed Methods Study

* 14-CC-0057:
Collection of Blood From Healthy Volunteers and Clinical Research Subjects for the Production of Clinical Grade Induced Pluripotent Stem Cell (iPSC) Products

* 14-CC-0027:
The NIH Exercise Therapy for Advanced Lung Disease Trials: Response and Adaptation to Aerobic Exercise in Patients with Interstitial Lung Disease

* 14-C-0184:
Phase 1 Study of the Safety and Tolerability of ATR-101 in Adrenocortical Carcinoma

* 14-C-0168:
A Phase I Clinical Trial of T-Cells Targeting B-Cell Maturation Antigen for Previously Treated Multiple Myeloma

* 14-C-0163:
Transformation of Plexiform Neurofibromas to Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis Type 1: Clinical, Histopathologic, and Genomic Analysis

* 14-C-0161:
Phase I Trial of the Combination of Bortezomib and Clofarabine in Adults with Refractory Solid Tumors, Lymphomas, or Myelodysplastic Syndromes

* 14-C-0156:
A Phase II Single Arm Pilot Study of the Chk1/2 Inhibitor (LY2606368) In BRCA1/2 Mutation Associated Breast or Ovarian Cancer, Triple Negative Breast Cancer, High Grade Serous Ovarian Cancer, And Metastatic Castrate-Resistant Prostate Cancer

* 14-C-0131:
A Phase II, Open-Label Study in Patients with BRAF V600E-Mutated Rare Cancers with Several Histologies to Investigate the Clinical Efficacy and Safety of the Combination Therapy of Dabrafenib and Trametinib

* 14-C-0129:
Phase 1 Study of a Combination of the PARP Inhibitor, Niraparib and Temozolomide or Irinotecan in Patients with Previously Treated, Incurable Ewing's Sarcoma

* 14-C-0128:
Collection of Pharmacokinetic Samples from Patients with Unanticipated Response or Toxicity

* 14-C-0116:
A Randomized Controlled Trial Evaluating an Enhanced Physical Activity Intervention to Improve Cognitive Late Effects in ChildrenTreated with Cranial Radiation for BrainTumors

* 14-C-0110:
Phase I-II Study of the Treatment of Metastatic Cancer that Expresses MAGE-A3 Using Lymphodepleting Conditioning Followed by Infusion of Anti-MAGE-A3 HLA-A*01 Restricted TCR-Gene Engineered Lymphocytes and Aldesleukin

* 14-C-0107:
Evaluation of Ferumoxytol Enhanced MRI for the Detection of Lymph Node Metastases in Genitourinary (Prostate, Bladder and Kidney)Cancers

* 14-C-0105:
Tissue Procurement and Natural History Study of Patients with Non-Small Cell Lung Cancer, Small Cell Lung Cancer, Extrapulmonary Small Cell Cancer, Pulmonary Neuroendocrine Tumors, and Thymic Epithelial Tumors

* 14-C-0104:
A Phase II Study Using Autologous Young Tumor-Infiltrating Lymphocytes (TIL) Derived from Patients with Non-Small Cell Lung Cancer Following Non-Myeloablative Lymphocyte Depleting Preparative Regimen

* 14-C-0090:
A Phase 2 Open-Label Study to Evaluate the Efficacy and Safety of VT-464 in Patients with Metastatic Castration Resistant Prostate Cancer Who Have Previously Been Treated with Enzalutamide, Androgen Receptor Positive Triple-Negative Breast Cancer Patient

* 14-C-0079:
An Exploratory Study of Voicing My CHOiCES as a Tool for Advanced Care Planning in Young Adults with Cancer and Other Chronic Illnesses

* 14-C-0052:
Phase I/II Study of the Treatment of Metastatic Cancer that Expresses MAGE-A3 Using Lymphodepleting Conditioning Followed by Infusion of HLA-DP0401/0402 Restricted Anti-MAGE-A3 TCR-Gene Engineered Lymphocytes and Aldesleukin

* 14-C-0037:
A Phase 2 Study of the MET Kinase Inhibitor INC280 in Papillary Renal Cell Cancer

* 14-C-0036:
A Randomized, Prospective, Phase II Study to Determine the Efficacy of Bacillus Calmette-Guerin (BCG) Given in Combination with PANVAC[TM] Versus BCG Given Alone in Adults with High Grade Non-Muscle Invasive Bladder Cancer (NMIBC) Who Failed at Least 1 I

* 14-C-0022:
A Phase II Study for Metastatic Melanoma using High Dose Chemotherapy Preparative Regimen followed by Cell Transfer Therapy Using Tumor Infiltrating Lymphocytes Plus IL-2 with the Administration of Pembrolizumab in the Retreatment Arm

* 14-C-0021:
Randomized Control Trial of Adrenalectomy versus Observation for Subclinical Hypercortisolism

* 14-C-0004:
A Multicenter Phase 2 Study of the Bruton's Tyrosine Kinase Inhibitor PCI-32765 (Ibrutinib) for Treatment of Relapsed Hairy Cell Leukemia

* 14-AT-0100:
Effects of Transcranial Magnetic Stimulation (TMS) on Somatosensory Perception

* 14-AR-0200:
Studies of the Natural History, Pathogenesis, and Outcome of Idiopathic Systemic Vasculitis

* 14-AA-0192:
Brain Inflammation and Function in Alcoholism

* 14-AA-0181:
Unit and Clinic Evaluation, Screening, Assessment, and Management

* 14-AA-0144:
Reliability Of The Human Brain Connectome

* 14-AA-0094:
Neural Substrate of Approach-Avoidance Conflict

* 14-AA-0080:
Characterization Imaging Instruments in Alcoholics and Non-Alcoholics

* 14-AA-0066:
Behavioral and Functional MRI Task Development, Implementation, and Testing

* 13-N-0188:
Natural History and Biomarkers of C9ORF72 Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

* 13-N-0165:
Electrical Impedance Myography: Exploratory Studies in Normal Subjects and Patients with Neuromuscular Disorders

* 13-N-0149:
Screening and Recruitment for HIV-associated Neurocognitive Disorders (HAND) Studies and an Evaluation of HIV-associated Neurocognitive Disorders in Virologically Controlled Patients

* 13-N-0140:
Cerebrospinal Fluid Collection and Repository Storage

* 13-N-0135:
Pilot Study of Raltegravir, an Integrase Inhibitor, in Human T-Cell Lymphotrophic Virus-1(HTLV-1) Associated Myelopathy, Tropical Spastic Paraparesis (HAM/TSP)

* 13-N-0088:
Open Label Extension Trial of Idebenone for Primary Progressive Multiple Sclerosis

* 13-N-0085:
Clinical Manifestations and Biorepository for Focal Dystonia

* 13-N-0076:
Gamma Frequency Transcranial Magnetic Stimulation in Dystonia

* 13-N-0017:
Natural History Study of Progressive Multifocal Leukoencephalopathy (PML)

* 13-M-0190:
Imaging and Genetic Investigation of Learning and Decision Making

* 13-M-0100:
Brain Inflammation In Major Depressive Disorder

* 13-M-0028:
Diagnosis and Treatment of Childhood-onset Behavioral Disorders, Neuropsychiatric Disorders and Neurodevelopmental Disorders

* 13-I-0181:
Microbiomic and Immunologic Profiling of Women with Antibiotic induced Vaginal Candidiasis

* 13-I-0157:
The Natural History of GATA2 Deficiency and Related Disorders

* 13-I-0117:
Radiofrequency Ablation (RFA) for the Treatment of Liver Abscesses in Patients with Chronic Granulomatous Disease

* 13-I-0082:
Rituximab (Anti-CD20) for the Treatment of Subjects With Anticytokine Autoantibody-Associated Diseases

* 13-HG-0199:
NIH Participation to USIDNET Registry

* 13-HG-0171:
Randomized Trial of Consent Interventions for NIH Whole Exome and Whole Genome Sequencing Studies

* 13-HG-0053:
The NIH Mini Study: Metabolism, Infection and Immunity in Inborn Errors of Metabolism

* 13-H-0197:
Evaluation of Serum Concentrations of Budesonide in Patients Treated for Gastrointestinal Graft-Versus-Host Disease and the Potential Interaction with Fluconazole or Voriconazole

* 13-H-0194:
Inflammatory Characterization of Known or Possible Cardiovascular Diseases

* 13-H-0183:
Cardiovascular Health and Needs Assessment in Washington D.C. - Development of a Community-Based Behavioral Weight Loss Intervention

* 13-H-0144:
Peripheral Blood Stem Cell Allotransplantation For Hematological Malignancies Using Ex Vivo CD34 Selection - a Platform For Adoptive Cellular Therapies

* 13-H-0133:
Extended Dosing with Eltrombopag in Refractory Severe Aplastic Anemia

* 13-H-0123:
An Exploratory Study to Evaluate the Effects of Roflumilast on Insulin Sensitivity and Metabolic Parameters in Prediabetic Overweight and Obese Individuals

* 13-H-0116:
A Multicenter Safety Study of Unlicensed, Investigational Cryopreserved Cord Blood Units (CBUs) Manufactured by the National Cord Blood Program (NCBP) and Provided for Unrelated Hematopoietic Stem Cell Transplantation of Pediatric and Adult Patients

* 13-H-0065:
Human Translational Studies of Inflammation and Cardiometabolic Diseases: The Psoriasis, Atherosclerosis and Cardiometabolic Disease (PACI) Initiative

* 13-H-0059:
Longitudinal Observational Study of Severe Asthma

* 13-H-0051:
Bronchodilator Effects of Nebulized Versus Inhaled Albuterol In Subjects With Lymphangioleiomyomatosis

* 13-EI-0072:
Microbiome and Ocular Inflammatory Disease

* 13-EI-0049:
Genetics of Uveal Coloboma

* 13-E-0015:
Environmental Risk Factors for the Development of Myositis in Military Personnel

* 13-DK-0200:
The Mechanism of Human Non-Shivering Thermogenesis and Basal Metabolic Rate

* 13-DK-0196:
Evaluation of Sickle Cell Liver Disease

* 13-DK-0090:
Identifying Risk for Diabetes and Heart Disease in Women: A Study of African-American, African and White Federal Employees and Contractors

* 13-DK-0057:
Short Term Effects of Leptin Withdrawal or Initiation in Lipodystrophy Independent of Energy Intake

* 13-DK-0002:
Treatment for Non-Alcoholic Fatty Liver with Different Doses of Vitamin E

* 13-D-0033:
Diagnosis and Treatment of Patients in Need of Third Molar Removal and Oral Specimen Acquisition

* 13-CH-0112:
Pilot Study to Assess Biomarkers of Changes in Barrier Function of Skeletal Muscle in Patients with a Fragile Sarcolemmal Muscular Dystrophy

* 13-CH-0097:
Fat Metabolism and Function Altering Polymorphisms in MC3R

* 13-CC-0210:
Evaluating an Extension Assist Knee Ankle Foot Orthosis to Improve Crouch Gait in Cerebral Palsy

* 13-CC-0180:
Studies of the Human Microbiome in Clinical Center Patients

* 13-CC-0110:
Near-infrared Spectroscopy and Electroencephalography to Assess and Train Cortical Activation During Motor Tasks

* 13-CC-0099:
Vasti Control of Patellofemoral Kinematics in Patients with Chronic Patellofemoral Pain

* 13-CC-0079:
Fusion Guided Thermal Ablation Combined With External Beam Radiation for Hepatic Neoplasms

* 13-CC-0012:
A Natural History Study of Novel Biomarkers in Pulmonary Arterial Hypertension

* 13-CC-0003:
Imaging Techniques in fMRI and fMRI Reproducibility: An NIH/FDA Interagency Collaboration

* 13-C-0214:
Phase II Study of Metastatic Cancer that Expresses NY-ESO-1 Using Lymphodepleting Conditioning Followed by Infusion of Anti-NY ESO-1 Murine TCR-Gene Engineered Lymphocytes

* 13-C-0202:
Tissue Procurement and Natural History Study of Patients with Malignant Mesothelioma and Other Mesothelin Expressing Cancers

* 13-C-0193:
Evaluation of (68)Gallium- DOTATATE PET/CT for Detecting Primary and Metastatic Neuroendocrine Tumors

* 13-C-0176:
Tumor, Normal Tissue and Specimens from Patients Undergoing Evaluation or Surgical Resection of Solid Tumors

* 13-C-0175:
A Phase II Protocol for Subjects with Stage T1 Bladder Cancer to Evaluate Selective Bladder Preserving Treatment by Radiation Therapy Concurrent with Radio-sensitizing Chemotherapy following a Thorough Transurethral Surgical Re-Staging

* 13-C-0132:
Allogeneic Hematopoietic Stem Cell Transplant for Patients with Mutations in GATA2 or the MonoMAC Syndrome

* 13-C-0131:
A Pilot Study of Inpatient Hospice with Procurement of Tissue on Expiration in Thoracic Malignancies

* 13-C-0119:
Evaluation of Local Response of Prostate Cancer to Irradiation Using Multiparametric MRI and MR-Guided Biopsies

* 13-C-0118:
A Phase I Trial of TRC102 (methoxyamine HCl) in Combination with Temozolomide in Patients with Relapsed Solid Tumors and Lymphomas

* 13-C-0105:
Molecular Profiling-based Assignment of Cancer Therapy for Patients With Advanced Solid Tumors

* 13-C-0095:
A Phase 2 Study of GI-6207 in Patients with Recurrent Medullary Thyroid Cancer

* 13-C-0071:
A Phase 2 Study of Anakinra in Inflammatory Pustular Dermatoses: Evaluation of Therapeutic Efficacy and Validation of Pathogenic Mechanisms

* 13-C-0063:
A Phase I, Open-Label, Multiple-Ascending Dose Trial to Investigate the Safety, Tolerability, Pharmacokinetics, Biological and Clinical Activity of Avelumab (MSB0010718C), a Monoclonal Anti-PD-L1 Antibody, in Subjects with Metastatic or Locally Advanced

* 13-C-0044:
A Phase 2 Study of Cabozantinib (XL184), a Dual Inhibitor of MET and VEGFR, in Patients With Metastatic Refractory Soft Tissue Sarcoma

* 13-C-0032:
A Phase I Study of Single-agent AZD1775 (MK-1775), a Wee1 Inhibitor, in Patients with Advanced Refractory Solid Tumors

* 13-C-0016:
A Phase I Study of an Adenoviral Transduced Autologous Dendritic Cell Vaccine Expressing Human HER2/neu ECTM in Adults with Tumors with 1-3+ HER2/neu Expression

* 13-C-0006:
Phase II Trial Evaluating the Safety and Efficacy of Ruxolitinib in Patients with Smoldering and Chronic Adult T-cell Leukemia (ATL)

* 13-AR-0056:
Stopping Tumor Necrosis Factor-Alpha Inhibitors in Rheumatoid Arthritis

* 13-AG-0078:
Resveratrol and Cardiovascular Health in the Elderly: The Reache Trial

* 13-AG-0034:
Phase I, Double-Blind, Placebo-Controlled, Ascending, Single-Dose, Safety, Tolerability and Pharmacokinetic Study of Bisnorcymserine (BNC), a Highly Selective Inhibitor of Butyrylcholinesterase, in Healthy Adult Volunteers

* 12-NR-0195:
Evaluation and Treatment Protocol for Potential Research Participants with Digestive Disorders

* 12-N-0182:
Positron Emission Tomography Measurement of Neuroinflammation in Focal Epilepsy

* 12-N-0137:
A Phase 1 Open-Label Dose Escalation Safety Study of Convection Enhanced Delivery (CED) of Adeno-Associated Virus Encoding Glial Cell Line-Derived Neurotrophic Factor (AAV2-GDNF) in Subjects with Advanced Parkinson's Disease

* 12-N-0122:
Integrating Genetic and Environmental Risk Scores into an Algorithm to Predict Multiple Sclerosis Susceptibility

* 12-N-0095:
Clinical and Molecular Manifestations of Neuromuscular and Neurogenetic Disorders of Childhood

* 12-N-0083:
The Effectiveness of Botulinum Toxin on Persistent Pelvic Pain in Women with Endometriosis

* 12-N-0065:
Experienced Breacher Study: Evaluation of the Effects from Chronic Exposure to Low-Level Blast

* 12-N-0060:
Structural and Functional Brain Imaging Markers of Upper Motor Neuron Function

* 12-N-0031:
Imaging Biomarkers in Parkinson Disease

* 12-N-0007:
Prospective Evaluation of the Effect of Corticotropin-Releasing Hormone Stimulation on 18F-Fludeoxyglucose High-Resolution Positron-Emission Tomography in Cushing's Disease

* 12-M-0128:
TMS Investigations of the Human Visual System

* 12-M-0063:
PET Imaging of Translocator Protein in Subjects with Traumatic Brain Injury

* 12-I-0157:
Clinical Outcomes in Persons with HIV Acquired Early in Life (COPE)

* 12-I-0121:
Screening of Volunteers for Clinical Trials of Investigational and Licensed Vaccines, Antiviral Products, or Live Virus Challenge Studies

* 12-I-0026:
Assessment of Glucocorticoid Responsiveness and Mechanisms of Resistance in Hypereosinophilic Syndromes

* 12-HG-0202:
The Neurobehavioral, Environmental and Genetic Factors Impacting the Clinical Course of Attention Deficit Hyperactivity Disorder

* 12-HG-0181:
The Clinical Study of Patients with Sex Chromosome Variants

* 12-HG-0161:
Therapeutic Trial of EPI -743 In Patients with Disorders of Energy Utilization or Oxidation-Reduction

* 12-HG-0023:
The Role of the Family Genetics Health Educator in Influencing Health Promoting Behaviors

* 12-HG-0022:
Inherited Diseases, Caregiving, and Social Networks

* 12-H-0158:
Quantitative Myocardial Perfusion, Myocardial Scarring and Their Contribution to Late Clinical Decompensation in Adults with Congenital Heart Disease

* 12-H-0150:
Eltrombopag Added to Standard Immunosuppression in Treatment-Naive Severe Aplastic Anemia

* 12-H-0141:
Prospective Evaluation of New Techniques in Radiation Reduction for Cardiovascular Computed Tomographic Angiography

* 12-H-0110:
An Open-label, Non-Randomized, Single-Arm Pilot Study to Evaluate the Effectiveness of Etidronate Treatment for Arterial Calcifications due to Deficiency in CD73 (ACDC)

* 12-H-0064:
A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs) for Transplantation in Pediatric and Adult Patients with Hematologic Malignancies and Other Indications

* 12-EI-0203:
Natural History of ABCA4-Related Retinopathies

* 12-EI-0042:
NEI Intramural Biorepository for Retinal Diseases

* 12-E-0089:
Bisphenol A (BPA) Pharmacokinetic (PK): Controlled Exposure Study

* 12-E-0061:
The Role of the Functionally Relevant Single Nucleotide Polymorphisms CYP2J2 -50G>T (CYP2J2 7) and EPHX2 9846A>G (EPHX2 K55R) in Human Endothelial Function

* 12-DK-0154:
Evaluation of Patients with Gastrointestinal Disease

* 12-DK-0097:
Energy Expenditure Responses to Different Temperatures

* 12-DC-0152:
Normative Values in Audiovestibular Testing

* 12-D-0100:
Oral Microbial and Immunological Characterization of Patients with Immune Dysfunction

* 12-CH-0050:
Hormonal Regulation of Puberty and Fertility

* 12-CH-0049:
The Molecular Basis of Inherited Reproductive Disorders

* 12-CC-0211:
A Pilot Study of the Effect of Spironolactone Therapy on Exercise Capacity and Endothelial Dysfunction in Pulmonary Arterial Hypertension

* 12-CC-0200:
Neurovascular Magnetic Resonance Imaging in the Assessment of HIV-Associated Neurocognitive Disorders

* 12-CC-0139:
Estimation of Brain Biomechanics using MRI

* 12-CC-0096:
Collection of Granulocytes by Apheresis of Healthy Donors Stimulated with Filgrastim (G-CSF) and Dexamethasone

* 12-C-0206:
Understanding the Perceived Influence of Childhood Cancer and NF1 on the Parents' Marital/Partner Relationship: A Descriptive Study

* 12-C-0204:
A Phase I and Randomized Phase II Multicenter Study of Cabozantinib (XL184) plus Docetaxel and Prednisone in Metastatic Castrate Resistant Prostate Cancer

* 12-C-0196:
A Phase 2 Multicenter, Investigator Initiated Study of Oral Ruxolitinib Phosphate for the Treatment of Relapsed or Refractory Diffuse Large B-cell and Peripheral T-cell Non-Hodgkin Lymphoma

* 12-C-0193:
Lymphoid Malignancies and Precursors: Tissue Acquisition Protocol

* 12-C-0178:
Longitudinal Assessment and Natural History Study of Children and Young Adults with MEN2A or MEN2B with or without Medullary Thyroid Carcinoma

* 12-C-0175:
Prospective Procurement of Solid Tumor Tissue to Identify Novel Therapeutic Targets

* 12-C-0159:
Effects of Treatments on the Microbiome in Healthy Volunteers and Patients with Atopic Dermatitis

* 12-C-0113:
A Phase I Study of a Continuous Intravenous Infusion of Recombinant Human Interleukin IL-15 (rhIL-15) in Adults with Metastatic Cancers

* 12-C-0111:
Phase I/II Study of Metastatic Cancer Using Lymphodepleting Conditioning Followed by Infusion of Anti-mesothelin Gene Engineered Lymphocytes

* 12-C-0066:
Phase I Trial of Oral 5-Fluoro-2'-Deoxycytidine with Oral Tetrahydrouridine in Patients with Advanced Solid Tumors

* 12-C-0047:
A Phase I/II Study of the Safety, Pharmacokinetics and Efficacy of Pomalidomide (CC-4047) in the Treatment of Kaposi Sarcoma in Individuals With or Without HIV

* 12-C-0014:
Phase 0 Trial of [F-18]-5-Fluoro-2'-Deoxycytidine with Tetrahydrouridine

* 12-AR-8001:
Compassionate Use Treatment Protocol I4V-MC-JAGA; Treatment of Autoinflammatory Syndromes Expected to Benefit from JAK Inhibition

* 11-NR-0014:
Investigating Molecular-Genetic Correlates of Fatigue Experienced by Cancer Patients Receiving Treatment

* 11-N-0211:
Deep Brain Stimulation Surgery for Movement Disorders

* 11-N-0157:
Analysis of Visual-Motor Task Electrophysiological Activity During Deep Brain Stimulation for Treatment-Resistant Movement Disorders

* 11-N-0116:
Manganese-Enhanced Magnetic Resonance Imaging in Healthy Volunteers and People with Multiple Sclerosis

* 11-N-0084:
Evaluation and Diagnosis of Potential Research Subjects with Traumatic Brain Injury (TBI)

* 11-N-0055:
The Effect of Transcranial Magnetic Stimulation on Learning with Reward in Healthy Humans

* 11-N-0051:
Surgery as a Treatment for Medically Intractable Epilepsy

* 11-N-0039:
A Phase II Clinical Trial of PRX-00023 Therapy in Localization-Related Epilepsy

* 11-M-0251:
A Longitudinal Investigation of the Endocrine and Neurobiologic Events Accompanying Puberty

* 11-M-0118:
Neuroimmune Activation in Austism: Imaging Translocator Protein Using Positron Emission Tomography (PET)

* 11-M-0045:
Development of Magnetic Resonance Spectroscopic Imaging Techniques for Imaging Metabolites in Human Brain and Muscle

* 11-I-0187:
The Natural History, Immunologic Correlates and Genetic Defects in Patients with Mucocutaneous and Invasive Fungal Infections

* 11-I-0183:
Screening of Volunteers for Influenza Human Challenge and Vaccine Studies

* 11-I-0164:
VRC 500:Screening of Volunteers for Clinical Trials of Investigational Products and Licensed Products Evaluated for Research Purposes

* 11-I-0109:
Viral Infections in Healthy and Immunocompromised Hosts

* 11-I-0007:
Lentiviral Gene Transfer for Treatment of Children Older Than 2 Years of Age with X-Linked Severe Combined Immunodeficiency

* 11-HG-0218:
A Natural History Study of Patients with GNE Myopathy

* 11-HG-0207:
Clinical and Basic Investigations Into Erdheim-Chester Disease

* 11-HG-0110:
Genetics of Obesity, Diabetes, and Heart Disease in African Diaspora Populations

* 11-HG-0093:
Personalized Genomic Research

* 11-H-0134:
A Pilot Study of a Thrombopoietin-Receptor Agonist (TPO-R Agonist), Eltrombopag, in Moderate Aplastic Anemia Patients

* 11-H-0091:
Real-Time MRI Right Heart Catheterization Using Passive Catheters

* 11-H-0068:
Phase II Trial of Cyclosporine Inhalation Solution (CIS) in Lung Transplant and Hematopoietic Stem Cell Transplant Recipients for Treatment of Bronchiolitis Obliterans

* 11-H-0064:
Extension Study (Extended Access) of Cyclosporine Inhalation Solution (CIS) in Lung Transplant and Hematopoietic Stem Cell Transplant Recipients for the Treatment of Bronchiolitis Obliterans

* 11-EI-0264:
A Pilot Study for the Evaluation of Minocycline as a Microglia Inhibitor in the Treatment of Central Retinal Vein Occlusions

* 11-EI-0263:
A Pilot Study for the Evaluation of Minocycline as a Microglia Inhibitor in the Treatment of Branch Retinal Vein Occlusions

* 11-EI-0245:
Generation of Induced Pluripotent Stem (iPS) Cell Lines from Somatic Cells of Participants with Eye Diseases and from Somatic Cells of Matched Controls

* 11-EI-0147:
Longitudinal Investigation of Dark Adaptation in Participants with Age-Related Macular Degeneration

* 11-E-0072:
Environmental Risk Factors for the Anti-Synthetase Syndrome

* 11-E-0006:
The Role of TGF-Beta in Asthmatic Epithelial Cell Susceptibility to RSV Infection

* 11-DK-0168:
Magnetic Resonance of Body, Arterial Wall and Angiography Imaging for Non-Invasive Assessment of Arterial Distensibility, Endothelial Dysfunction and Atherosclerotic Disease Using 1.5T High Field (3T) MRI: A Technical Development Study of Cardiac and Bod

* 11-DK-0108:
Observational Study of Persons with Hepatitis B Virus Infection in North America (Cohort Study)

* 11-DK-0023:
The Nephrotic Syndrome Study Network (NEPTUNE)

* 11-D-0172:
The Pathogenesis and Natural History of Sjogren s Syndrome

* 11-CH-0208:
Effects of the Glucocorticoid Antagonist, Mifepristone, on Glucose Intolerance in Obese and Overweight Individuals

* 11-CH-0179:
Next Generation Sequencing to Identify Genetic Causes of Disease in Patients Participating in NICHD Clinical Protocols

* 11-CH-0004:
Free Fatty Acids, Body Weight, and Growth Hormone Secretion in Children

* 11-CC-0152:
The Natural History of Liver Disease in a Cohort of Participants with Hepatitis B and/or Hepatitis C with or without HIV Infection

* 11-CC-0120:
Stereophotogrammetry of the Torso in Normal Individuals and Patients with Scoliosis, Chest Wall Deformations, or Obesity

* 11-C-0266:
A Phase I/II Study of the Safety and Feasibility of Administering T Cells Expressing Anti-EGFRvIII Chimeric Antigen Receptor to Patients with Malignant Gliomas Expressing EGFRvIII

* 11-C-0255:
Clinical, Epidemiologic, and Genetic Studies of Li-Fraumeni Syndrome

* 11-C-0242:
Collection of Blood from Patients with Cancer for Analysis of Genetic Differences in Drug Disposition

* 11-C-0233:
Pilot Study of Tocilizumab in Patients with Symptomatic Kaposi Sarcoma Herpesvirus (KSHV) - Associated Multicentric Castleman Disease

* 11-C-0225:
First In-Human Phase I Trial of NHS-IL12 in Patients with Metastatic Solid Tumors

* 11-C-0220:
Natural History Study of the KSHV Inflammatory Cytokine Syndrome (KICS) Incorporating Pilot Evaluation of KSHV Targeted Therapies

* 11-C-0200:
A Phase II Trial In Which Patients With Metastatic Alveolar Soft Part Sarcoma Are Randomized to Either Sunitinib or Cediranib Monotherapy, with Cross-Over at Disease Progression

* 11-C-0191:
Phase 1 and Phase II and Re-Treatment Study of AZD6244 for Recurrent or Refractory Pediatric Low Grade Glioma

* 11-C-0190:
Collection of Tissue Blocks or Slides from Patients with Cancer

* 11-C-0161:
A Phase 1/2 Study of the Mitogen Activated Protein Kinase Kinase(MEK) 1 Inhibitor Selumetinib (AZD6244, Hydrogen Sulfate) in Children with Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas (PN)

* 11-C-0149:
Evaluation of Diagnostic and Prognostic Molecular Markers in Adrenal Neoplasm

* 11-C-0125:
Study of the Biology and Natural History of Disease Outcomes in Patients Treated with Allogeneic Hematopoietic Stem Cell Transplantation for Hematologic Malignancies

* 11-C-0113:
A Pilot Study of Genetically Engineered NY-ESO-1 Specific (c259) T Cells in HLA-A2+ Patients with Synovial Sarcoma

* 11-C-0112:
Acquisition of Blood and Tumor Tissue Samples from Patients with Gastrointestinal Cancer

* 11-C-0096:
Pilot Trial of Molecular Profiling and Targeted Therapy for Advanced Non-Small Cell Lung Cancer, Small Cell Lung Cancer, and Thymic Malignancies

* 11-C-0061:
Phase I Trial of Z-Endoxifen in Adults with Refractory Hormone Receptor-Positive Breast Cancer, Desmoid Tumors, Gynecologic Tumors, or other Hormone Receptor-Positive Solid Tumors

* 11-C-0060:
A Phase I Pharmacokinetic Study of Belinostat for Solid Tumors and Lymphomas in Patients with Varying Degrees of Hepatic Dysfunction

* 11-C-0034:
DICER1-Related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History Study

* 11-C-0016:
Rapamycin-Resistant T Cell Therapy of Multiple Myeloma: Relapse Prevention and Relapse Therapy

* 11-AR-0223:
Studies on the Natural History and Pathogenesis of Spondyloarthritis

* 11-AA-0028:
Dietary Linoleic Acid Regulation of Omega-3HUFA Metabolism: Satiety and Body Composition Among Overweight Female Subjects

* 10-N-0185:
Neural Dynamics and Connectivity in Response Inhibition and Traumatic Brain Injury

* 10-N-0143:
A Prospective Natural History Study of Patients with Syringomyelia

* 10-N-0122:
Evaluation, Pathogenesis, and Outcome of Subjects with or Suspected Traumatic Brain Injury

* 10-N-0012:
Screening Protocol for Patients with Stroke

* 10-M-0112:
Defining the Brain Phenotype of Children with Williams Syndrome

* 10-M-0047:
Top-Down Attentional Control of Visual-Processing

* 10-M-0027:
Cognitive Neuroscience of Autism Spectrum Disorders

* 10-I-0216:
Studies of Disorders with Increased Susceptibility to Fungal Infections

* 10-I-0197:
Admission and Management of Occupational or Other Exposures to Biodefense/Bioterrorism Agents or to Epidemic/Emerging Infectious Diseases

* 10-I-0195:
Training Protocol on the Natural History of Tuberculosis

* 10-I-0148:
Natural History of Atopic Dermatitis and Other Genetic/Congenital Diseases Associated with Allergic Inflammation

* 10-I-0109:
VRC 900: Evaluation of Tissue-Specific Immune Responses in Adults 18 Years of Age and Older

* 10-I-0095:
Collection of Peripheral Blood Stem Cells Using G-CSF and Plerixafor in Healthy Volunteers

* 10-I-0029:
Non-Invasive Assessment of Atherosclerosis in Patients with CGD and Other Disorders of the Immune System

* 10-I-0014:
The Natural History of Severe Viral Infections and Characterization of Immune Defects

* 10-HG-0065:
Whole Genome Medical Sequencing for Gene Discovery

* 10-H-0168:
Submission of Autologous and Related Allogeneic Hematopoietic Stem Cell Transplant Data to the Center for International Blood and Marrow Transplant Research (CIBMTR) and the National Marrow Donor Program (NMDP)

* 10-H-0154:
Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused with a Reduced Dose of Non-Mobilized Donor T-Cells

* 10-H-0126:
Cardiovascular Disease Discovery Protocol

* 10-H-0097:
A Study of the Kinetics of Lymphoid Cells in Patients with Monoclonal B-Cell Lymphocytosis (MBL), Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL), Mantle Cell Lymphoma (MCL) and Healthy Volunteers.

* 10-H-0039:
New Techniques to Evaluate Mitral Regurgitation

* 10-EI-0140:
Genotype-Phenotype Study of Patients with Plaquenil -Induced Retinal Toxicity, with Evaluation of the ABCA4 Gene

* 10-EI-0093:
Immunogenetic Mechanisms in Behcet's Disease

* 10-E-0130:
The Role of Glucocorticoid Receptor SNPs in Receptor Function and Metabolic Disease

* 10-E-0129:
Study of the Effect of Innate Immunity on the Inflammatory Response to Endotoxin

* 10-E-0063:
Sample Collection Registry for Quality Control of Biological and Environmental Specimens and Assay Development and Testing

* 10-DK-0163:
Metabolic Effects of Non-Nutritive Sweeteners

* 10-CH-0198:
Testing and Calibration of Non-Invasive Optical Imaging Technology for Functional Brain Imaging

* 10-CC-0118:
Long Term Clinical Correlates of TBI: Imaging, Biomarkers, and Clinical Phenotyping Parameters

* 10-CC-0115:
Imaging Techniques in MRI

* 10-CC-0053:
Collection of Bone Marrow from Healthy Volunteers and Patients for the Production of Clinical Bone Marrow Stromal Cell (BMSC) Products

* 10-C-0201:
Apheresis and CD34+ Selection of Mobilized Peripheral Blood CD34+ Cells from Patients with DOCK8 Deficiency, LAD-1, and GATA2 Deficiency

* 10-C-0174:
Related and Unrelated Donor Hematopoietic Stem Cell Transplant of DOCK8 Deficiency

* 10-C-0166:
A Phase II Study Using Short-Term Cultured, Autologous Tumor-Infiltrating Lymphocytes Following a Lymphocyte Depleting Regimen in Metastatic Cancers Plus the Administration of Pembrolizumabat Time of Progression

* 10-C-0114:
A Phase II Study of Bevacizumab and Erlotinib in Subjects with Advanced Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) or Sporadic Papillary Renal Cell Cancer

* 10-C-0111:
Protocol for the Enrollment on the Official COG Registry, The Childhood Cancer Research Network (CCRN) Children s Oncology Group

* 10-C-0102:
Clinical and Genetic Studies in Familial Non-Medullary Thyroid Cancer

* 10-C-0086:
Comprehensive Omics Analysis of Pediatric Solid Tumors and Establishment of a Repository for Related Biological Studies

* 10-C-0066:
Collection of Human Samples to Study Hairy Cell and Other Leukemias and to Develop Recombinant Immunotoxins for Cancer Treatment

* 10-C-0052:
Phase II Study of Dose-Adjusted EPOCH+/-Rituximab in Adults with Untreated Burkitt Lymphoma, c-MYC Positive Diffuse Large B-Cell Lymphoma and Plasmablastic Lymphoma

* 10-C-0025:
Randomized Phase II Trial of Rituximab with Either Pentostatin or Bendamustine for Multiply Relapsed or Refractory Hairy Cell Leukemia

* 09-NR-0088:
Molecular-Genetic Correlates of Fatigue in Cancer Patients Receiving Localized External Beam Radiation Therapy

* 09-NR-0064:
Brain-Gut Interactions in Overweight and Normal Weight Patients with Chronic Abdominal Pain

* 09-N-0118:
Investigation of Neurofeedback with Real-Time fMRI in Healthy Volunteers and Patients with Hyperkinetic Movement Disorders

* 09-N-0032:
Comprehensive Multimodal Analysis of Neuroimmunological Diseases of the CNS

* 09-M-0176:
Functional Relevance of Dopamine Receptors in Healthy Controls and Patients with Schizophrenia: Characterization through [11C]NNC-112 and [18F]Fallypride Positron Emission Tomography

* 09-M-0034:
A Controlled Trial of Citalopram Added to Methylphenidate in Youth with Severe Mood Dysregulation

* 09-I-0232:
An International Observational Study to Characterize Adults Who Are Hospitalized with Complications of Influenza

* 09-I-0200:
A Phase I Study of Mozobil (TM) in the Treatment of Patients with WHIMS

* 09-I-0184:
Studies in the Pathogenesis of Systemic Capillary Leak Syndrome

* 09-I-0133:
Establishing Fibroblast-derived Cell Lines from Skin/Tissue Biopsies of Patients with Immunodeficiency or Immunodysregulation Disorders

* 09-I-0129:
A Randomized Double-Blinded, Placebo-Controlled Study of Omalizumab for Idiopathic Anaphylaxis

* 09-I-0126:
Pathogenesis of Physical Induced Urticarial Syndromes

* 09-I-0102:
Etiology, Pathogenesis, and Natural History of Idiopathic CD4+ Lymphocytopenia

* 09-I-0086:
Screening Protocol for Genetic Diseases of Allergic Inflammation and Mast Cell Homeostasis and Activation

* 09-I-0049:
Normal Blood, Bone Marrow and Buccal Mucosa Protocol

* 09-I-0030:
Clinical and Immunologic Monitoring of Patients with Known or Suspected HIV Infection

* 09-I-0013:
Biomarkers of Inflammation, Coagulation, and Endothelial Function in HIV-Infected Adults

* 09-HG-0128:
Leukodystrophies of Unknown Cause

* 09-HG-0035:
Clinical, Cellular, and Molecular Investigations into Oculocutaneous Albinism

* 09-H-0199:
A Pilot Study of a Thrombopoietin-Receptor Agonist (TPO-R agonist), Eltrombopag, in Patients with Low to Int-2 Risk Myelodysplastic Syndrome (MDS)

* 09-H-0172:
Natural History of Bronchiectasis & Bronchiectasis Patient Registry

* 09-DK-0223:
Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy

* 09-DK-0140:
Natural History of Autoimmune Diabetes and Its Complications

* 09-DK-0097:
Vitamin E Pharmacokinetics and Biomarkers in Women

* 09-CH-0059:
Molecular Bases of Response to Copper Treatment in Menkes Disease, Related Phenotypes, and Unexplained Copper Deficiency

* 09-C-0242:
Prospective Comprehensive Molecular Analysis of Endocrine Neoplasms

* 09-C-0214:
A Multi-Histology Phase II Study of 5-Fluoro-2'-Deoxycytidine with Tetrahydrouridine (FdCyd + THU)

* 09-C-0192:
Phase II Study of Cediranib (AZD2171) in Patients With Alveolar Soft Part Sarcoma

* 09-C-0161:
Follow Up Protocol for Subjects Previously Enrolled in NCI Surgery Branch Studies

* 09-C-0120:
An Exploratory Evaluation of Biomarkers in Blister Fluid in Healthy Volunteers and Irradiated Skin

* 09-C-0100:
A Pilot Study of High Dose Rate Brachytherapy in The Radiation Oncology Branch

* 09-C-0053:
Autologous and Related Allogeneic Hematopoietic Stem Cell Transplant and Cellular Therapies Data Submission to the Center for International Blood and Marrow Transplant Research (CIBMTR) and the National Marrow Donor Program (NMDP)

* 09-C-0005:
Randomized Trial of Cladribine (CdA) with Simultaneous or Delayed Rituximab to Eliminate Hairy Cell Leukemia Minimal Residual Disease

* 08-NR-0132:
Evaluation and Diagnosis of Potential Research Subjects with Pain and Fatigue Syndromes

* 08-I-0221:
Analysis of HIV-1 Replication During Antiretroviral Therapy

* 08-I-0184:
Studies in the Pathogenesis of Idiopathic Anaphylaxis

* 08-HG-0059:
Studies of Skin Microflora in Healthy Individuals and Atopic Dermatitis Patients

* 08-H-0186:
Safety and the Anti-Tumor Effects of Escalating Doses of Adoptively Infused Ex Vivo Expanded Autologous Natural Killer (NK) Cells Against Metastatic Cancers or Hematological Malignancies Sensitized to NK TRAIL Cytotoxicity with Bortezomib

* 08-H-0185:
Technical Development of Interventional Cardiovascular Magnetic Resonance Imaging in Healthy Volunteers

* 08-H-0156:
Screening of Subjects to Determine Eligibility to Safely Participate in Blood Disorders Studies

* 08-H-0105:
Natural History Study of Monoclonal B Cell Lymphocytosis (MBL), Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma(CLL/SLL), Lmphoplasmacytic Lymphoma(LPL)/Waldenstrom Macroglobulinemia (WM), and Splenic Marginal Zone Lymphoma(SMZL)

* 08-H-0046:
Co-Infusion of Umbilical Cord Blood and Haploidentical CD34+ Cells Following Nonmyeloablative Conditioning as Treatment for Severe Aplastic Anemia and MDS Associated with Severe Neutropenia Refractory to Immunosuppressive Therapy

* 08-EI-0102:
Screening Study for the Evaluation and Diagnosis of Potential Research Participants

* 08-EI-0099:
Epigenetics, Molecular Genetics, and Biomarkers of Degenerative and Inflammatory Ocular Diseases

* 08-EI-0043:
Age-Related Eye Disease Study (AREDS) and AREDS2 Follow-Up

* 08-EI-0031:
Visual Motor Coordination

* 08-DK-0138:
A New Method for Determining Gastric Acid Output Using a Wireless Capsule

* 08-DK-0098:
Natural History of Familial Carcinoid Tumor

* 08-DK-0004:
High Sensitivity Screening of Compound Libraries to Discover a Drug for the Treatment of Sickle Cell Disease

* 08-C-0214:
A Pilot Study to Evaluate Neuropsychological Outcome Measures and their Relationship with Prognosis in Patients Receiving Radiation Therapy for Brain Metastases

* 08-C-0079:
Natural History Study and Longitudinal Assessment of Children, Adolescents, and Adults with Neurofibromatosis Type 1

* 08-AG-0238:
Development of 3T Magnetic Resonance Research Methods for NIA Studies

* 08-AA-0178:
Computer-Assisted Self-Administration of Ethanol (CASE) in Humans

* 07-N-0190:
Neurobiological Studies of Psychogenic Movement Disorders and Non-Epileptic Seizures

* 07-N-0122:
Modulation of Motor Function by Stimulation of the Central and Peripheral Nervous System

* 07-M-0021:
Development of Functional and Structural Magnetic Resonance Imaging Techniques for the Study of Mood and Anxiety Disorders

* 07-I-0229:
Influenza in the Non-immunocompromised and Immunocompromised Host

* 07-I-0183:
The Collection of Research Samples and/or Data for Repository from Related or Unrelated Hematopoietic Stem Cell Transplantation Recipients for the National Marrow Donor Program

* 07-I-0075:
Allogeneic and Matched Unrelated Donor Stem Cell Transplantation for Congenital Immunodeficiencies or Patients with Autoinflammatory/Immunodysregulatory Conditions: Busulfan-Based Conditioning with Campath- 1H or h-ATG, Radiation, and Sirolimus

* 07-I-0033:
Screening Protocol for Detection and Characterization of Infections and Infection Susceptibility

* 07-HG-0076:
A Phase One Treatment Trial of the Circadian Sleep Disturbance in Smith-Magenis Syndrome (SMS)

* 07-HG-0002:
ClinSeq: A Large-Scale Medical Sequencing Clinical Research Pilot Study

* 07-H-0157:
Suburban/NHLBI Cardiovascular Disease Screening Protocol

* 07-H-0142:
Research Respiratory Tract Procedures

* 07-H-0113:
Collection of Blood, Bone Marrow, and Buccal Mucosa Samples from Healthy Volunteers

* 07-H-0030:
Metabolic Regulation by Tumor Suppressor p53 in Li-Fraumeni Syndrome

* 07-H-0005:
Pilot Study of Topical Dexamethasone 0.01% Solution for Prevention of Oral Chronic Graft Versus Host Disease

* 07-E-0023:
Innate Immunity Signal Transduction in Human Leukocytes

* 07-DK-0115:
Natural History of Type 2 Diabetes Mellitus in Children and Young Adults

* 07-DK-0077:
Study of the Phenotype of Overweight and Obese Adults

* 07-CH-0192:
Detection and Treatment of Endocrine Abnormalities in Childhood Cancer Survivors and Hematopoitic Stem Cell Transplant Recipients

* 07-C-0110:
Analysis of Stored Data Collected from Individuals Administered Neurobehavioral Assessments on IRB-Approved Protocols

* 07-C-0100:
Collection of Blood from Patients with Prostate Cancer

* 07-C-0086:
Pilot Study of Educational Interventions in Pediatric Hematopoietic Stem Cell Donors to Increase Knowledge of Donation and Transplantation Procedures

* 06-N-0047:
Reference Values for Plasma Catechols

* 06-M-0214:
PET Measurement of Regional Rates of Cerebral Protein Synthesis in Subjects with Fragile X Syndrome

* 06-M-0065:
Screening Protocol for Studies of the Pediatrics and Developmental Neuroscience Branch

* 06-I-0153:
A Pilot Study of Hepatic Fibrosis in HIV/AIDS Patients with Chronically Elevated Transaminases on Antiretroviral Therapy

* 06-I-0015:
Screening Protocol for Genetic Diseases of Lymphocyte Homeostasis and Programmed Cell Death

* 06-H-0190:
Treatment of T-Large Granular Lymphocyte (T-LGL) Lymphoproliferative Disorders with Alemtuzumab (Campath)

* 06-EI-0068:
The Vitreous Proteome and Inflammatory Mediators in Ocular Inflammatory Disease

* 06-DK-0142:
Peripheral Blood Collection of Adult Stem Cells

* 06-CH-0186:
Evaluation of Biochemical Markers and Clinical Investigation of Niemann-Pick Disease, Type C

* 06-CH-0011:
Natural History Study of Patients with Excess Androgen

* 06-C-0219:
An Exploratory Study of Biologic and Pathophysiologic Effects of Radiation Therapy in Pediatric Patients with Central Nervous System Tumors

* 06-C-0213:
Tissue Procurement Protocol for the Developmental Therapeutics Clinic, National Cancer Institute (NCI)

* 06-C-0051:
AIDS-Related Primary Central Nervous System Lymphoma: A Phase II Pilot Study of High-Dose Intravenous Methotrexate with Rituximab Leucovorin Rescue and Highly Active Antiretroviral Therapy

* 06-C-0014:
Prospective Evaluation of Epigenetic Alterations in Patients with Thoracic Malignancies

* 05-N-0223:
Clinical Neurophysiology: Training and Normative Values

* 05-M-0144:
MRS (Magnetic Resonance Spectroscopy) Measurement of Glutamate and GABA Metabolism in Brain

* 05-I-0219:
Analysis of Erythema Migrans Lesions

* 05-I-0213:
Screening and Baseline Assessment of Patients with Abnormalities of Immune Function

* 05-HG-0131:
Clinical Study of Muenke Syndrome (FGFR3-Related Craniosynostosis)

* 05-H-0130:
Long-Term Evaluation and Follow Up Care of Patients Treated with Allogeneic Stem Cell Transplants

* 05-DK-0085:
Clinical and Laboratory Investigation of Humans with Informative Iron or Erythroid Phenotypes

* 05-CC-0091:
Electromagnetic Tracking of Devices During Interventional Procedures

* 04-N-0071:
Phase I/II Study of HTLV-I-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP) Using the Humanized MiK-Beta-1 Monoclonal Antibody Directed Toward the IL-2/IL-15R-Beta Subunit (CD122) that Blocks IL-15 Action

* 04-M-0222:
Investigation of the Rapid (Next Day) Antidepressant Effects of an NMDA Antagonist

* 04-I-0286:
A Longitudinal Study of Familial Hypereosinophilia (FE): Natural History and Markers of Disease Progression

* 04-I-0266:
Collection of Peripheral Blood, Urine, Sputum, and Bone Marrow from Healthy Donors for Use in In Vitro Research

* 04-HG-0211:
Procurement and Analysis of Specimens from Individuals with Pulmonary Fibrosis

* 04-HG-0127:
Clinical and Basic Investigations of Methylmalonic Acidemia (MMA) and Related Disorders

* 04-HG-0093:
Clinical and Genetic Studies on Holoprosencephaly

* 04-H-0202:
Mutations in Genes Associated with Pentalogy of Cantrell

* 04-H-0161:
Studies of the Natural History of Sickle Cell Disease

* 04-H-0012:
Collection of Blood, Bone Marrow, Urine, and/or Tissue Samples from Patients with Solid Tumors, Hematological Malignancies or Non-Malignant Hematologic Disorders or HLA Compatible Family Members

* 04-E-0053:
Environmental Polymorphism Registry (EPR)

* 04-DK-0021:
Urinary Vitamin C Loss in Subjects with and without Diabetes

* 04-CH-0250:
Event Related Potentials from Infancy to Adulthood

* 04-CH-0077:
Screening and Diagnosis of Patients with Connective Tissue Disorders

* 04-CC-0119:
Biomarkers and Protein Mass Expression Profiles in Bronchoalveolar Lavage from Patients with Lung Infiltrates

* 04-C-0281:
Natural History Study of Clinical and Biological Factors Determining Outcomes in Chronic Graft-Versus-Host Disease

* 04-C-0275:
Targeted Oncolytic Virotherapy and Natural History Study of KSHV-Associated Multicentric Castleman's Disease with Laboratory and Clinical Correlates of Disease Activity

* 04-C-0274:
Follow-Up of Study Subjects Previously Enrolled in Immunotherapy Studies Utilizing Gene Transfer or Other Immunotherapeutic Agents

* 04-C-0200:
Urinary and Serum VEGF and MMP Levels in Patients Receiving Radiation Therapy for Glioblastoma Multiforme: Prospective Determination of a Predictive Value for Recurrence

* 04-C-0165:
Care of the Adult Oncology Patient, CCR, NCI

* 04-C-0102:
Hematologic Malignancy Biology Study

* 04-AR-0205:
Progression of Spinal Fusion in Ankylosing Spondylitis

* 03-N-0164:
Evaluation and Treatment of Neurosurgical Disorders

* 03-N-0004:
Clinical Laboratory Evaluation of Primary Chronic Autonomic Failure

* 03-M-0211:
Family Study of Affective and Anxiety Spectrum Disorders

* 03-M-0186:
The Psychobiology of Temperament: An fMRI Study

* 03-M-0138:
A Screening Protocol to Evaluate Women with Postpartum-Related Mood and Behavioral Disorders

* 03-M-0093:
Predictability and Aversive Expectancies in Anxiety and Depressive Disorders

* 03-I-0263:
VRC 200: A Multicenter Specimen Collection Protocol to Obtain Human Biological Samples for Research Studies

* 03-H-0280:
Disease Pathogenesis and Natural History of Lipid Disorders

* 03-H-0250:
Technical Development of Interventional Cardiovascular Magnetic Resonance Imaging

* 03-H-0170:
Nonmyeloablative Allogeneic Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation For Severe Congenital Anemias Including Sickle Cell Disease (SCD) and Beta-Thalassemia

* 03-H-0168:
Natural History and Molecular Characterization of Benign Ethnic Neutropenia in Individuals of African Descent

* 03-H-0105:
The Determination of Genetic Basis Of Immunodeficiency

* 03-H-0015:
Human Specimen Collection to Support Basic and Clinical Research

* 03-EI-0122:
Evaluation of Immune Responses to Different Antigens in Non Infectious Ocular Inflammatory Diseases

* 03-EI-0033:
X-Linked Juvenile Retinoschisis - Clinical and Molecular Studies

* 03-E-0099:
Pathogenic Studies In Families With Twins Or Siblings Discordant For Systemic Rheumatic Disorders

* 03-DK-0257:
Effect of Leptin Therapy in the Treatment of Severe Insulin Resistance

* 03-DK-0256:
Inhibition of Intestinal Glucose Absorption by the Bioflavonoid Quercetin in the Obese and in Obese Type 2 Diabetics

* 03-CC-0060:
Virtual Functional Anatomy (VFA)

* 03-C-0278:
A Comparative Study of Pediatric CNS Tumor Activity as Assessed by [18]F-FDG PET Imaging and Proton Magnetic Resonance Spectroscopic Imaging ([1]H-MRSI)

* 03-C-0277:
Cell Harvest and Preparation for Surgery Branch Adoptive Cell Therapy Protocols

* 03-C-0241:
The Natural History of Childhood Malignancies Treated with Radiation Therapy

* 03-C-0145:
Evaluation of the Natural History and Management of Pancreatic Lesions Associated with Von Hippel-Lindau

* 03-C-0066:
Hereditary Leiomyomatosis Renal Cell Cancer (HLRCC): Identification of the Disease Gene and Characterization of the Predisposition to Renal Cancer

* 03-AR-0173:
Studies of the Natural History, Pathogenesis, and Outcome of Autoinflammatory Diseases (NOMID/CAPS, DIRA, CANDLE, SAVI, CRMO, Still s Disease, Behcet s Disease, and other Undifferentiated Autoinflammatory Diseases)

* 03-AR-0131:
Genetic Determinants of Ankylosing Spondylitis Severity - Longitudinal Study

* 03-AG-0325:
Longitudinal Studies of Human Physiology, Biochemistry, and Psychology (The Baltimore Longitudinal Syudy of Aging - BLSA)

* 02-N-0014:
Research Study of Specimens Obtained During Epilepsy Surgery

* 02-M-0321:
fMRI Investigation of Explicit Cue and Contextual Fear

* 02-M-0021:
Characterization and Pathophysiology of Severe Mood and Behavioral Dysregulation in Children and Youth

* 02-I-0286:
Efficacy of Tyrosine Kinase Inhibition in Reducing Eosinophilia in Patients with Myeloid and/or Steroid-Refractory Hypereosinophilic Syndrome

* 02-I-0277:
Regulation of the Proliferation and Survival of Normal and Neoplastic Human Mast Cells

* 02-I-0202:
Leukapheresis Procedures to Obtain Plasma and Lymphocytes for Research Studies on Antiretroviral Naive HIV-Infected Patients

* 02-I-0147:
Genetic Studies of Chronic Active Epstein-Barr Virus Infection

* 02-I-0110:
Natural History of Anthrax: A Study of Primary Infected, Recovered, and Exposed (SPoRE) Individuals and Evaluation of AVA Vaccinated Recipients

* 02-I-0086:
Evaluation of Viral Factors and Immune Parameters to Study HIV-Specific Immunity

* 02-I-0055:
Evaluation, Treatment and Follow up of Patients with Lyme Disease

* 02-HG-0107:
Investigation of Neurodegeneration in the Glycosphingolipid Storage Disorders

* 02-H-0160:
Peripheral Blood Stem Cell Collection from Adult Volunteers

* 02-H-0050:
Technical Development of Cardiovascular Magnetic Resonance Imaging

* 02-CH-0311:
Investigations into Inborn Errors of Cholesterol Synthesis and Related Disorders

* 02-CC-0266:
Acute Cardiac Allograft Cellular Rejection and Cardiac Allograft Vasculopathy: Identification of Diagnostic Biomarkers and Target Pathways for Preventive Therapy

* 02-C-0313:
Cancer Risk in Xeroderma Pigmentosum Heterozygotes

* 02-C-0211:
Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of Melanoma

* 02-C-0210:
Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of Blood and Lymph Node Malignancy

* 02-C-0179:
Biospecimen Acquisition from Human Subjects

* 02-C-0178:
Multidisciplinary Etiologic Study of Familial Testicular Cancer

* 02-C-0159:
The Birt Hogg-Dube Syndrome: Identification of the Disease Gene and Characterization of the Predisposition of Renal Cancer

* 02-C-0077:
Characterization of High Risk Breast Duct Epithelium by Cytology, Breast Duct Endoscopy, and cDNA Gene Expression Profile

* 02-C-0064:
Collection of Peripheral Blood and/or Urine From Patients Undergoing Radiation Therapy

* 02-C-0052:
Etiologic Investigation of Cancer Susceptibility in Inherited Bone Marrow Failure Syndromes: A Natural History Study

* 02-AR-0131:
Collection Of Blood Components Using Apheresis from Patients with Rheumatic or Kidney Diseases and Healthy Volunteers

* 01-N-0206:
Phenotype/Genotype Correlations in Movement Disorders

* 01-N-0139:
Evaluation and Treatment of Patients with Epilepsy

* 01-N-0007:
Evaluation, Pathogenesis, and Treatment of Patients with or at Risk for Cerebrovascular Disease (A Natural History/Disease Pathogenesis Protocol)

* 01-M-0254:
The Evaluation of Patients with Mood and Anxiety Disorders and Healthy Volunteers

* 01-M-0232:
Positron Emission Tomography (PET) Scanning in Dopamine Disorders: Parkinson's Disease and Schizophrenia

* 01-M-0192:
Fluoxetine's Effects on Attention and Emotional Memory in Anxious and Depressed Youth and Adults

* 01-M-0185:
Effects of Arousal and Stress on Classical Conditioning

* 01-I-0238:
Diagnosis and Treatment of Leishmanial Infections

* 01-I-0226:
Evaluation of Immune Response to Vaccines in Primary Immune Disorders

* 01-I-0202:
Natural History, Genetics, Phenotype and Treatment of Mycobacterial Infections

* 01-I-0161:
Identification of Novel Viruses

* 01-HG-0109:
Natural History Study of the Clinical and Molecular Manifestations of Smith-Magenis Syndrome (SMS)

* 01-H-0198:
Clinical Course in Cystic Fibrosis: The Effects of Pseudomonas Aeruginosa and Potential Modifier Genes

* 01-H-0122:
Collection and Storage of Umbilical Cord Hematopoietic Stem Cells for Sickle Cell Disease Therapy

* 01-H-0088:
Determining the Prevalence and Prognosis of Secondary Pulmonary Hypertension in Adult Patients with Sickle Cell Anemia

* 01-DK-0062:
Genetic Analysis of Familial Keloids

* 01-DC-0230:
Studies of Deficits in the Sense of Taste

* 01-DC-0229:
Genetic Analysis of Hereditary Disorders of Hearing and Balance

* 01-DC-0228:
Clinical and Molecular Analysis of Enlarged Vestibular Aqueducts

* 01-DC-0099:
Evaluation for NIDCD Head & Neck Surgery Branch Clinical Research Protocols

* 01-D-0184:
Evaluation and Treatment of Bone and Mineral Disorders

* 01-CC-0231:
A Prospective Study of Transfusion-Transmitted Infections

* 01-CC-0045:
Studies of Phlebotomy Therapy in Hereditary Hemochromatosis

* 01-C-0158:
Protocol to Assess Vascularity in Kaposi's Sarcoma Lesions Utilizing Non-Invasive Imaging Techniques

* 01-C-0157:
Eligibility Screening and Tissue Procurement for the National Cancer Institute (NCI), Pediatric Oncology Branch (POB) Clinical Research Protocols

* 01-C-0129:
Eligibility Screening and Tissue Procurement for the National Cancer Institute Center for Cancer Research Clinical Protocols

* 01-C-0070:
Evaluation of the Natural History of Patients with Tumors of the Central Nervous System

* 01-C-0038:
Collection of Blood, Bone Marrow, Tumor, or Tissue Samples from Patients with HIV Infection, KSHV Infection, Viral-Related Pre-Malignant Lesions, and/or Cancer

* 01-C-0030:
Short-Course EPOCH-Rituximab in Untreated CD-20+ HIV-Associated Lymphomas

* 01-AR-0227:
Studies of the Natural History of Rheumatic Disease in Minority Communities

* 00-N-0089:
Genetic Analysis of the Chiari I Malformation

* 00-N-0082:
Characterization of Brain Morphology and Activity Using Functional and Anatomical MRI Contrast

* 00-N-0043:
Clinical and Molecular Manifestations of Inherited Neurological Disorders

* 00-M-0198:
The Phenomenology and Neurophysiology of Affective Dysregulation in Children and Adolescents with Bipolar Disorder

* 00-M-0085:
Structural and Functional Imaging of Neuropsychiatric Patients and Normal Volunteers with 3.0 Tesla MRI and Magnetoencephalography

* 00-I-0159:
Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection Syndrome (HIES)

* 00-HG-0209:
Molecular and Clinical Studies of Primary Immunodeficiency Diseases

* 00-HG-0153:
Investigations into Chediak-Higashi Syndrome and Related Disorders

* 00-HG-0141:
Clinical, Biochemical, and Molecular Investigations into Alkaptonuria

* 00-H-0051:
Cutaneous Tumorigenesis in Patients with Tuberous Sclerosis

* 00-DK-0107:
Search for Novel Methods to Detect Acute Renal Failure

* 00-CH-0160:
Clinical and Molecular Analysis of ACTH-Independent Steroid Hormone Production in Adrenocortical Tissue

* 00-CH-0127:
Evaluation of Patients with Endocrine-Related Conditions

* 00-CH-0093:
Diagnosis, Pathophysiology, and Molecular Biology of Pheochromocytoma and Paraganglioma

* 00-C-0181:
Evaluation for NCI Radiation Oncology Branch Clinical Research Protocols

* 00-C-0078:
Collection of Blood, Fluid, Bone Marrow, Tumor, or Tissue Samples from Patients with Cancer or Normal Volunteers

* 00-C-0074:
Evaluation of Late Effects and Natural History of Disease in Patients Treated with Radiotherapy

* 00-AR-0222:
Studies of the Pathogenesis and Natural History of Arthritis and Related Conditions

* 99-M-0172:
Integrating EEG/MEG and fMRI: Activity Correlation between Frontal and Temporal Lobe Structures in Schizophrenic Patients, Their Siblings and Unrelated Normal Volunteers

* 99-I-0084:
Studies of Human Pneumocystis Infection

* 99-H-0076:
Asthma Sample Collection Protocol

* 99-H-0050:
Non-Myeloablative Allogeneic Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Hematologic Malignancies in High Risk Patients and in Patients with Debilitating Hematologic Diseases

* 99-H-0037:
Apheresis of Family Members of Patients Undergoing Allogeneic Bone Marrow Transplantation. A Pre-Clinical Study of Selective Depletion of Donor Lymphocytes to Prevent Acute Graft-Versus-Host Disease

* 99-DK-0002:
Diabetes and Heart Disease Risk in Blacks

* 99-CH-0103:
Evaluation of Women and Men with Endocrine and Reproductive-Related Conditions

* 99-CH-0055:
New Imaging Modalities in the Evaluation of Patients with Ectopic Cushing's Syndrome

* 99-CC-0168:
Collection and Distribution of Blood Components from Healthy Donors for In Vitro Research Use

* 99-C-0128:
Evaluation for NCI Surgery Branch Clinical Research Protocols

* 99-C-0099:
Examination of Clinical and Laboratory Abnormalities in Patients with Defective DNA Repair: Xeroderma Pigmentosum, Cockayne Syndrome, or Trichothiodystrophy

* 99-AR-0004:
Molecular Basis of Primary Immunodeficiencies

* 98-N-0047:
Immuno-Virological Evaluation of Human T Cell Leukemia Virus Type-1 Associated Myelopathy (HAM/TSP)

* 98-I-0027:
The Characterization of CD34+ Derived Mast Cell Precursors Mobilized by Administration of Granulocyte Colony Stimulating Factor and Plerixafor

* 98-HG-0249:
Genetic Analysis of Brain Disorders

* 98-H-0062:
Role of Exotoxins in the Pathogenesis of Pseudomonas Aeruginosa

* 98-D-0145:
Screening and Natural History of Patients with Polyostotic Fibrous Dysplasia and the McCune-Albright Syndrome

* 98-CH-0081:
Clinical and Basic Investigations into Smith-Lemli-Opitz Syndrome

* 98-CC-0090:
Evaluation of Hematologic Patients - Training Protocol

* 98-CC-0019:
Volunteer Scanning on MR

* 98-C-0037:
Treatment of Children with Cancer

* 97-I-0191:
Studies of Lymphocyte Kinetics Using Stable Isotopes

* 97-I-0096:
Evaluation, Treatment, and Monitoring of Patients With Known or Suspected Parasitic Infection

* 97-H-0061:
Evaluation and Treatment of Pulmonary Patients not Participating in Research (Training Protocol)

* 97-H-0041:
Screening Protocol for Subjects Being Evaluated for Hematology Branch Protocols

* 97-H-0022:
Bronchoscopy in Patients with Pulmonary Diseases and Research Volunteers

* 97-DC-0057:
Genetic Studies of Stuttering

* 97-CH-0076:
A Clinical and Genetic Investigation of Pituitary and HYPOTHALAMIC Tumors and Related Disorders

* 97-CH-0064:
Evaluation and Intervention for Ambulation, Growth, and Basilar Invagination in Osteogenesis Imperfecta

* 97-C-0147:
Collection of Serum and Tissue Samples from Patients with Biopsy-Proved or Suspected Malignant Disease

* 97-C-0143:
Collection of Blood, Bone Marrow and Tissue Samples for the Investigation of the Human Immune Response, Lymphoma Biology and HTLV-1 Infection

* 96-I-0129:
Evaluation and Long Term Follow-up of Patients with Allergic and Inflammatory Disorders

* 96-I-0052:
A Comprehensive Clinical, Microbiological and Immunological Assessment of Patients with Suspected Chronic Lyme Infection and Selected Control Populations

* 96-H-0100:
Role of Genetic Factors in the Pathogenesis of Lung Disease

* 96-H-0049:
Use of Granulocyte Colony Stimulating Factor (G-CSF) Mobilized Leukapheresis Collections from Healthy Volunteers to Develop Improved Methods of Stem Cell and Lymphocyte Selection for Allogeneic Transplantation

* 96-C-0102:
Evaluation and Treatment of Subjects with Dermatologic Diseases

* 96-C-0097:
The Acquisition of Blood and Skin Samples from Patient Volunteers to Support Research Activities on Dermatologic and Other Diseases

* 96-C-0071:
Follow-up for Patients Previously Enrolled on the Center for Cancer Research Protocols

* 95-M-0150:
A Neurobiological Investigation of Patients with Schizophrenia Spectrum Disorders and Their Siblings

* 95-M-0097:
An Endocrine Model for Postpartum Mood Disorders

* 95-I-0066:
Genetic Analysis of Immune Disorders

* 95-I-0027:
Virologic and Immunologic Evaluation of Lymph Node, Tonsillar, and Intestinal Biopsies, and Bronchoalveolar Lavage Fluid

* 95-HG-0193:
Clinical and Basic Investigations into Hermansky-Pudlak Syndrome

* 95-H-0186:
Characterization of the Pathogenesis of Lymphangioleiomyomatosis (LAM)

* 95-H-0047:
Diagnosis and Treatment of Patients with Heart and Vascular Disease (Training Protocol)

* 95-CH-0059:
Definition of the Genotype and Clinical Phenotype of Primary Pigmented Nodular Adrenocortical Disease (PPNAD), Carney Complex, Peutz-Jeghers Syndrome and Related Conditions

* 94-I-0079:
Eosinophil Activation and Function in Parasitic Infections and Other Conditions with Increased Tissue or Peripheral Blood Eosinophilia in Humans

* 94-I-0073:
Recruitment and Apheresis Collection of Peripheral Blood Hematopoietic Stem Cells,Mononuclear Cells and Granulocytes

* 94-HG-0132:
The Phenotype and Etiology of Proteus Syndrome and Related Overgrowth Disorders

* 94-HG-0105:
Genetics and Pathophysiology of Familial Mediterranean Fever and Related Disorders

* 94-H-0010:
Evaluation, Treatment and Training Protocol for Patients with Bone Marrow Failure States, Isolated or Multilineage Cytopenias, Metastatic Solid Tumors, or Hematologic Malignancies

* 94-E-0165:
Studies in the Natural History and Pathogenesis of Childhood-Onset and Adult-Onset Idiopathic Inflammatory Myopathies

* 94-DK-0133:
Genetic Markers for Focal Segmental Glomerulosclerosis

* 94-DK-0127:
Pathogenesis of Glomerulosclerosis

* 94-D-0018:
Salivary Evaluation in Healthy Volunteers

* 94-C-0074:
Treatment and Natural History Study of Lymphomatoid Granulomatosis

* 94-AR-0066:
Studies of the Pathogenesis and Natural History of Systemic Lupus Erythematosus (SLE)

* 93-N-0202:
Diagnosis and Natural History Protocol for Patients with Different Neurological Conditions

* 93-M-0170:
Regional Cerebral Blood Flow Studies of Object Perception, Identification, Localization, and Memory

* 93-I-0119:
Detection and Characterization of Host Defense Defects

* 93-I-0106:
Cryptococcosis in Previously Healthy Adults

* 93-I-0086:
Evaluation and Long Term Follow Up of Patients with Acute or Chronic Inflammatory Disorders

* 93-I-0063:
Study of the Immunopathogenesis, Natural History, and Genetics of Autoimmune Lymphoproliferative Syndrome (ALPS) Associated with an Expansion of CD4-8-/TCR alpha/beta+ T Cells

* 93-I-0057:
Apheresis Procedures to Obtain Plasma or Leukocytes for In Vitro Studies

* 93-DK-0127:
Family Studies in Metabolic Diseases and Mineral Metabolism

* 93-C-0133:
Dose-Adjusted EPOCH Chemotherapy and Rituximab (CD20+) in Adults and Children with Previously Untreated Patients with Aggressive Non-Hodgkin's Lymphoma

* 92-M-0174:
The Central Nervous System Effects of Pharmacologically Induced Hypogonadotropic Hypogonadism with and without Estrogen and Progesterone Replacement

* 92-I-0125:
A Study of Viral Burden in Peripheral Blood Versus Lymphoid and Bone Marrow Tissue in HIV-Infected Individuals

* 92-DK-0156:
Studies of Immunologically-Mediated Kidney Diseases

* 92-DK-0033:
Pharmacokinetics and Biodistribution of Ascorbic Acid in Healthy Human Subjects

* 91-I-0140:
Studies of the Pathogenesis of HIV Infection in Human Peripheral Blood Cells and/or Reproductive Fluids in HIV-Infected and HIV-Uninfected Volunteers

* 91-DK-0214:
Evaluation of Patients with Liver Disease

* 91-DK-0085:
Studies of Hyperparathyroidism and Related Disorders

* 91-DK-0066:
Fasting Hypoglycemia: Diagnosis and Treatment

* 91-CC-0117:
Epidemiology, Infectivity and Natural History of Hepatitis C Virus Infection in a Blood Donor Population

* 91-AR-0196:
Studies on the Natural History and Pathogenesis of Polymyositis, Dermatomyositis, and Related Diseases

* 90-M-0142:
Brain Procurement for the Human Brain Collection Core

* 90-M-0088:
The Treatment of Menstrually-Related Mood Disorders with the Gonadotropin Releasing Hormone (GnRH) Agonist, Depot Leuprolide Acetate (Lupron)

* 90-M-0014:
Studies of Frontal Lobe Function During Cognitive Stimulation as Measured with Oxygen-15 Water Positron Emission Tomography in Normal Subjects and Patients with Neuropsychiatric Disorders

* 90-I-0120:
Comparison of Inflammatory Responses in Normal Volunteers and Patients with Abnormal Phagocyte Function Using the Suction Blister Technique

* 90-CC-0168:
A Rigid Body Database on Human Movement

* 89-N-0045:
Evaluation of Progression in Multiple Sclerosis by Magnetic Resonance Imaging (MRI)

* 89-M-0160:
Inpatient Evaluation of Neuropsychiatric Patients

* 89-M-0006:
Brain Imaging of Childhood Onset Psychiatric Disorders, Endocrine Disorders and Healthy Volunteers

* 89-I-0158:
Studies of Immune Regulation in Patients with Common Variable Immunodeficiency and Related Humoral Immunodeficiency Syndromes

* 89-DK-0173:
Studies of States with Resistance to Vitamin D and Parathyroid Hormone

* 89-DK-0152:
Determination of Glomerular Filtration Rate, Effective Renal Plasma Flow and Glomerular Capillary Wall Permselectivity

* 89-C-0086:
Clinical Manifestations and Molecular Bases of Heritable Urologic Malignant Disorders

* 88-M-0131:
The Evaluation of Women with Perimenopause-Related Mood and Behavioral Disorders

* 88-I-0083:
Host Response to Infection and Treatment in the Filarial Diseases of Humans

* 87-I-0163:
Apheresis Procedures to Obtain Plasma or Leukocytes for In Vitro Studies

* 87-DK-0029:
Diagnosis and Treatment of Patients with Cystic Fibrosis and Other Disorders of the Respiratory System and Pancreas

* 87-CC-0091:
Magnetic Resonance Imaging at 1.5 and 3.0 Tesla

* 86-HG-0096:
Studies of Genetic Heterogeneity in Patients with Lysosomal Storage Disorders

* 85-N-0195:
A Training Protocol for the use of Botulinum Toxin in the Treatment of Neurological Disorders

* 85-I-0127:
Treatment of Cysticercosis including Neurocysticercosis with Praziquantel, Albendazole and other Novel Treatment Modalities

* 85-DK-0082:
Acromegaly Treatment and Natural History

* 84-M-0050:
Biochemical, Physiological, and Psychological Measures in Normal Controls and Relatives of Psychiatric Patients

* 83-C-0022:
Psychological Benefits of a Normalized Camping Experience for Children with Cancer

* 82-I-0183:
Study of the Immune Regulation of Idiopathic Inflammatory Bowel Diseases: Crohn's Disease, Ulcerative Colitis, and Other Inflammatory Conditions of the Gut

* 82-H-0032:
Comprehensive Evaluation of the Etiology and Pathogenesis of Chronic Lung Disease (Screening Protocol)

* 81-M-0126:
The Evaluation of Women with Menstrually Regulated Mood and Behavioral Disorders

* 81-I-0164:
Procedures to Obtain Plasma, Lymphocytes, or Other Specimens for Research Studies

* 80-M-0083:
Bipolar Genetics: A Collaborative Study

* 79-H-0100:
Teaching Protocol for the Evaluation of Plasma Lipoproteins

* 78-I-0023:
Diagnosis and Management of Inflammatory and Infectious Diseases

* 78-HG-0093:
Natural History Study of the Use of Cysteamine in the Treatment of Cystinosis

* 78-C-0039:
Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of Cancer

* 77-I-0094:
Study of Patients with Parasitic Infections of the Gastrointestinal Tract

* 77-DK-0096:
Studies on Thyroid Nodules and Thyroid Cancer

* 77-DK-0002:
Evaluation of Patients with Thyroid Function Disorders

* 76-HG-0238:
Diagnosis and Treatment of Patients with Inborn Errors of Metabolism or Other Genetic Disorders

* 76-H-0051:
Lipoprotein Metabolism in Normal Volunteers and Hyperlipoproteinemic Patients

* 76-DK-0006:
Natural History of Disorders of Insulin Resistance

Active Followup, Protocols NOT Recruiting New Patients 

* 17-H-0091:
Unrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS using CordIn(TM), Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells to Expedite Engraftment and Improve Transplant Outcome

* 17-H-0050:
Effect of Fish Oil Enriched In Omega-11 Fatty Acid On Lipoprotein Metabolism In Adults

* 17-EI-0071:
AMD Ryan Initiative Study (ARIS)

* 17-E-0003:
Collection of Biological and Environmental Samples and Clinical Data from Anonymous Adult Men and Women for Quality Control and Methods Development and Evaluation (ASCA)

* 17-CH-0078:
Setmelanotide (RM-493; Rhythm Pharmaceuticals, Inc.) Phase 2 Open-Label Treatment Trials in Patients with Rare Genetic Disorders of Obesity

* 17-C-0092:
A Phase I/II Study of Pexa-Vec Oncolytic Virus in Combination with Immune Checkpoint Inhibition in Refractory Colorectal Cancer

* 17-C-0089:
Evaluation of 18F-DCFPyL PSMA- versus 18F-NaF-PET imaging for Detection of Metastatic Prostate Cancer

* 17-C-0088:
A Phase II Trial of the DNA Methyl Transferase Inhibitor, Guadecitabine (SGI-110), In Children And Adults With Wild Type GIST, Pheochromocytoma And Paraganglioma Associated With Succinate Dehydrogenase Deficiency And HLRCC-Associated Kidney Cancer

* 17-C-0085:
A Phase 1, Open-label, Dose Escalation Study of MGA271 in Pediatric Patients with B7-H3-Expressing Relapsed or Refractory Solid Tumors

* 17-C-0082:
A Phase 2 Study of Pembrolizumab, a Monoclonal Antibody Against PD-1, in Combination with Capecitabine and Oxaliplatin (CAPOX) in Subjects with Advanced Biliary Tract Carcinoma (BTC)

* 17-C-0061:
Phase II Trial of Pembrolizumab in Recurrent or Metastatic Medullary Thyroid Cancer

* 17-C-0052:
Phase II Evaluation of Nivolumab, an Immune Checkpoint Inhibitor, Alone or in Combination with Oral Decitabine/Tetrahydrouridine as Second Line Therapy for Non-Small Cell Lung Cancer

* 17-C-0040:
Clinical Sequencing of Cancer and Tissue Repository: ClinOmics

* 17-C-0037:
Phase 0 Trial of LB100, A Protein Phosphatase 2A Inhibitor, in Recurrent Glioblastoma

* 17-C-0012:
Phase I Study of a Combination of MM-398 and Veliparib in Solid Tumors

* 16-N-0166:
Deep Brain Stimulation Surgery for Treatment of Focal Hand Dystonia

* 16-M-0105:
Evaluation of a Novel PET Radioligand to Image OGA

* 16-I-0148:
VRC 319: A Phase I/Ib, Randomized Clinical Trial to Evaluate the Safety and Immunogenicity of A Zika Virus DNA Vaccine, VRC-ZKADNA085-00-VP, in Healthy Adults

* 16-I-0119:
A Phase 1, Randomized Double-Blind, Placebo-Controlled, Single Ascending Dose Safety, Tolerability, and Pharmacokinetics Study of SAB-301 in Healthy Adults

* 16-H-0085:
Pilot Study to Evaluate the Effect of Fasting and Refeeding on T-Cell Fate

* 16-E-0096:
Cytochrome P450 Epoxygenase Pathway Regulation of Macrophage Function

* 16-DK-0167:
A Phase II Randomized, Placebo-Controlled, Double-Blind, Parallel Arms With Switchover, Pilot Study To Evaluate The Efficacy And Safety Of Intravenous Abatacept In Treatment Resistant Nephrotic Syndrome (Focal Segmental Glomerulosclerosis/Minimal Change)

* 16-CC-0168:
Focus Groups to Determine Surrogates Views Regarding Patient Preference Predictors

* 16-CC-0112:
Impact of Once-Weekly Rifapentine and Isoniazid on the Steady State Pharmacokinetics of Dolutegravir and Darunavir Boosted with Cobicistat in Healthy Volunteers

* 16-CC-0098:
Pilot Study of Fusion Guided Focal Laser Ablation of Prostate Cancer

* 16-CC-0056:
Analysis of a Tool to Assess Psycho Social Spiritual Healing: Cognitive Interviewing

* 16-C-0152:
Phase I/II Evaluation of Continuous 24h Intravenous Infusion of Mithramycin, an Inhibitor of Cancer Stem Cell Signaling, in Patients with Primary Thoracic Malignancies or Carcinomas, Sarcomas or Germ Cell Neoplasms with Pleuropulmonary Metastases

* 16-C-0145:
Phase II Trial with Safety Run-in of the Anti-Mesothelin Antibody Drug Conjugate Anetumab Ravtansine for Mesothelin Expressing Lung Adenocarcinoma

* 16-C-0097:
Phase 1 Trial of Panobinostat in Children with Diffuse Intrinsic Pontine Glioma

* 16-C-0045:
A Randomized, Open-Label, Active-Controlled, Phase II Study of Intravenous Anetumab Ravtansine (BAY 94-9343) or Vinorelbine in Patients with Advanced or Metastatic Malignant Pleural Mesothelioma Overexpressing Mesothelin and Progressed on First Line Plat

* 16-C-0034:
A Phase II Trial of Oral Pazopanib plus Oral Topotecan Metronomic Antiangiogenic Therapy for Recurrent Glioblastoma Multiforme (A)without Prior Bevacizumab Exposure and (B) after Failing Prior Bevacizumab

* 16-AA-0082:
Oxytocin in Alcohol Use Disorder: A Novel and Translational Approach

* 15-N-0177:
Investigation of Blood-Brain-Barrier Breakdown Using Manganese Magnetic Resonance Imaging in Drug-Resistant Epilepsy

* 15-N-0175:
A Multicenter, Open-Label, Phase 1b Safety and Efficacy Trial of Periganglionic Resiniferatoxin for the Treatment of Intractable Pain Due to Cancer-Induced Bone Pain

* 15-N-0057:
Physiological and Psychosomatic Effects of Exposure to MRI Scanning Environment

* 15-I-0169:
Sanaria PfSPZ Challenge with Pyrimethamine Chemoprophylaxis (PfSPZ-CVac Approach): Phase 1 Trial to Determine Safety and Protective Efficacy of Sanaria PfSPZ Challenge with Concurrent Pyrimethamine Treatment that Inhibits Development of Asexual Blood

* 15-I-0148:
A Phase I Study of Respiratory Syncytial Virus Human Challenge in Healthy Adult Volunteers

* 15-I-0113:
NIAID Clinical Center Genomics Opportunity Protocol

* 15-I-0083:
A Multicenter Randomized Safety and Efficacy Study of Putative Investigational Therapeutics in the Treatment of Patients with Known Ebola Infection

* 15-I-0044:
Phase 1 Study of the Safety and Immunogenicity of Pfs230D1M-EPA/Alhydrogel and Pfs25M-EPA/Alhydrogel, a Transmission Blocking Vaccine Against Plasmodium Falciparum Malaria in Adults in the US and Mali

* 15-I-0007:
Haploidentical Transplant for Patients with Chronic Granulomatous Disease (CGD) using Post-Transplant Cyclophosphamide

* 15-I-0001:
A Phase 1 Randomized, Double-Blind, Placebo Controlled, Dose-Escalation Study to Evaluate the Safety and Immunogenicity of Prime-Boost VSV Ebola Vaccine in Healthy Adults

* 15-HG-0068:
An Open-Label Phase 2 Study of ManNAc in Subjects with GNE Myopathy

* 15-HG-0006:
A Phase II Therapeutic Trial of the Use of Dabrafenib and Trametinib in Patients with BRAF V600E Mutation Positive Lesions in Erdheim Chester Disease

* 15-E-0104:
Study to Assess the Impact of Inhaled Silver Nanoparticles on Lung Cell Immune Response

* 15-DK-0192:
Quantifying Weight Regain and the Persistence of Metabolic Adaptation Following Extreme Weight Loss

* 15-DK-0170:
Treatment of Chronic Delta Hepatitis with Lonafarnib and Ritonavir

* 15-DK-0100:
A Multidisciplinary Approach to Deciphering the Mechanisms Involved In Microbial Translocation Across the Spectrum of HCV Associated Liver Fibrosis

* 15-C-0189:
A Randomized, Double-Blind, Placebo-Controlled Study of the Safety and Efficacy of Amatuximab in Combination with Pemetrexed and Cisplatin in Subjects with Unresectable Malignant Pleural Mesothelioma

* 15-C-0178:
A Phase Ib, Dose Escalation, Multiple Dose Trial with HuMax-IL8 in Patients with Metastatic or Unresectable, Locally Advanced Malignant Solid Tumors

* 15-C-0168:
A Phase I Trial of Pomalidomide for Children with Recurrent, Progressive or Refractory CNS Tumors

* 15-C-0099:
A Phase 1, Open-Label, Dose-Escalation Study of SNX-5422 and Everolimus in Subjects with Neuroendocrine Tumors

* 15-C-0050:
A Phase 2 Pilot Study of BMN 673 (Talazoparib), an Oral PARP Inhibitor, in Patients with Deleterious BRCA1/2 Mutation-Associated Ovarian Cancer Who Have Had Prior PARP Inhibitor Treatment

* 15-C-0046:
Phase 2 Study of MK-3475 in Patients with Microsatellite Unstable (MSI) Tumors

* 15-C-0045:
A Phase 2 Trial of the MEK Inhibitor PD-0325901 in Adolescents and Adults with NF1- Associated Morbid Plexiform Neurofibromas

* 15-C-0043:
A Phase II Study of Cabozantinib (XL184) for Plexiform Neurofibromas in Subjects with Neurofibromatosis Type 1 age 16 years or greater

* 15-C-0039:
Biomarkers in Acute Graft-Versus-Host Disease (GVHD) and Extracorporeal Photopheresis added to Investigator Chosen Therapies of Steroid Refractory Acute GVHD

* 15-C-0021:
A Pilot Study of AMP-224, a PD-1 Inhibitor, in Combination with Stereotactic Body Radiation Therapy (SBRT) in Patients with Metastatic Colorectal Cancer

* 15-C-0012:
A Phase II, Open-Label, Multicenter Trial to Investigate the Clinical Activity and Safety of Avelumab (MSB0010718C) in Subjects with Merkel Cell Carcinoma

* 15-C-0005:
A Phase I/II Study of T Cell Receptor Gene Therapy Targeting HPV-16 E6 for HPV-Associated Cancers

* 14-N-0169:
Dopamine Receptor Imaging to Predict Response to Stimulant Therapy in Chronic TBI

* 14-N-0132:
A Multicenter Observational Study to Assess the Variability of Molecular Biomarkers and Clinical Measures in Patients with Myotonic Dystrophy Type 1

* 14-N-0051:
A Two-Part Placebo-Controlled Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of BVS857 in Patients with Spinal and Bulbar Muscular Atrophy (SBMA)

* 14-M-0114:
Cognitive vs. Emotional Psycho-Pharmacological Manipulations of Fear vs. Anxiety

* 14-I-0115:
A Double-blind, Randomized, Placebo-controlled Study to Investigate the Efficacy and Safety of Mepolizumab in the Treatment of Eosinophilic Granulomatosis with Polyangiitis (EGPA) in Subjects Receiving Standard of Care Therapy

* 14-I-0063:
An Open-Label, Proof-of-Concept Study to Evaluate the Safety and Efficacy of Dexpramipexole (KNS-760704) in Subjects with Hypereosinophilic Syndrome

* 14-I-0050:
Imaging CXCR4 Expression in Subjects With Cancer Using 64 Cu-Plerixafor

* 14-HG-0038:
Treatment of SCID due to ADA Deficiency with Autologous Transplantation of Cord Blood or Hematopoietic CD 34+ Cells after Addition of a Normal Human ADA cDNA by the EFS-ADA Lentiviral Vector

* 14-H-0202:
A Phase II Trial of Losartan to Reverse Sickle Nephropathy

* 14-H-0190:
Vascular Inflammation in Psoriasis Extension (VIP-E) Trial

* 14-H-0147:
Multicenter Open-Label Study to Evaluate Efficacy of Gadobutrol-Enhanced Cardiac Magnetic Resonance Imaging (CMRI) for Detection of Significant Coronary Artery Disease (CAD) in Subjects with Known or Suspected CAD by a Blinded Image Analysis (GadaCAD2 at

* 14-H-0138:
Multicenter Open-Label Study to Evaluate Efficacy of Gadobutrol-Enhanced Cardiac Magnetic Resonance Imaging (CMRI) for Detection of Significant Coronary Artery Disease (CAD) in Subjects with Known or Suspected CAD by a Blinded Image Analysis

* 14-H-0130:
Observational Study for Detecting Kidney Damage in Patients with Sickle Cell Disease

* 14-H-0103:
Pilot Study to Evaluate the Effect of Fasting on the NLRP3 Inflammasome

* 14-H-0040:
A Trial to Determine the Effect of Psoriasis Treatment on Cardiometabolic Disease

* 14-H-0026:
Individual use of Ibrutinib for a Patient with Refractory Chronic Lymphocytic Leukemia.

* 14-EI-0108:
Pilot Study to Evaluate Oral Minocycline in the Treatment of Cystoid Macular Edema Associated with Retinitis Pigmentosa

* 14-EI-0078:
A Phase 2 Multicenter Randomized Clinical Trial of Ciliary Neurotrophic Factor (CNTF) for Macular Telangiectasia Type 2 (MacTel)

* 14-DK-0154:
Metabolic and Neural Adaptations to Weight Loss, Plateau, and Regain

* 14-DK-0084:
Evaluation of Safety, Tolerability, and Antiviral Activity of Chlorcyclizine HCl Alone or in Combination with Ribavirin in Patients with Chronic Hepatitis C

* 14-D-0145:
Open-Label Dose Escalation Study Evaluating the Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of Intravenous NPSP795 in Autosomal Dominant Hypocalcemia Due to Mutations in the Calcium-Sensing Receptor Gene: A Drug Repurposing Study

* 14-CH-0177:
Fertility Preservation in Females who will be undergoing Gonadotoxic Therapy, Hematopoietic Stem Cell Transplantation, and in Females with Sickle Cell Disease

* 14-CH-0102:
Phase 1/2 Study of Vorinostat Therapy in Niemann-Pick Disease, Type C1

* 14-CC-0087:
Sonalleve MR-HIFU for Palliation of Bone Pain: Pilot Study

* 14-C-0198:
A Multicenter Study of Ibrutinib and Lenalidomide in Combination with DA-EPOCH-R in Subjects with Relapsed or Refractory Diffuse Large B-cell Lymphoma

* 14-C-0175:
A Phase 2, Multicenter, Single-Arm Study of Moxetumomab Pasudotox in Pediatric Subjects with Relapsed or Refractory Pediatric Acute Lymphoblastic Leukemia (pALL) or Lymphoblastic Lymphoma of B-cell Origin

* 14-C-0157:
Phase 1 Study of Ibrutinib and Immuno-Chemotherapy Using Dose-Adjusted-Temozolomide, Etoposide, Doxil, Dexamethasone, Ibrutinib,Rituximab (DA-TEDDI-R) in Primary CNS Lymphoma

* 14-C-0150:
Phase I Study of Ganetespib and Ziv-Aflibercept in Patients with Advanced Gastrointestinal Carcinomas, Non-Squamous Non-Small Cell Lung Carcinomas, Urothelial Carcinomas, and Sarcomas

* 14-C-0142:
An Open Label Phase I Study to Evaluate the Safety and Tolerability of a Modified Vaccinia Ankara (MVA) Based Vaccine Modified to Express Brachyury and T-Cell Costimulatory Molecules (MVA Brachyury-TRICOM)

* 14-C-0140:
A Pilot Study of 18F-DCFBC PET/CT in Prostate Cancer

* 14-C-0113:
Effects of an Internet Support Group for Parents of a Child with Neurofibromatosis Type 1

* 14-C-0112:
A Phase II Study of Neoadjuvant rFowlpox-PSA (L155)-TRICOM (Prostvac-F/TRICOM) in Combination with rVaccinia-PSA (L155)-TRICOM (Prostvac-V/TRICOM) in Men with Prostate Cancer Undergoing Treatment with Radical Prostatectomy

* 14-C-0059:
A Phase I Trial of T Cells Expressing an Anti-GD2 Chimeric Antigen Receptor in Children and Young Adults with GD2+ Solid Tumors

* 14-C-0056:
Collection of Blood from Patients with Ovarian, Primary Peritoneal or Fallopian Tube Cancer

* 14-C-0053:
Adjuvant Tumor Lysate Vaccine and Iscomatrix With or Without Metronomic Oral Cyclophosphamide and Celecoxib in Patients with Malignancies Involving Lungs, Esophagus, Pleura, or Mediastinum

* 14-C-0029:
Natural History and Tissue Acquisition Study of Adrenocortical Carcinoma

* 14-C-0017:
A Randomized, Double-blind, Placebo-controlled Phase 3 Study of the Bruton's Tyrosine Kinase (BTK) Inhibitor, PCI-32765 (Ibrutinib), in Combination with Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (R-CHOP) in Subjects With Newly

* 14-C-0015:
Pilot Trial of BMN 673, an Oral PARP Inhibitor, in Patients With Advanced Solid Tumors and Deleterious BRCA Mutations

* 14-C-0013:
A Phase I/II Trial of Ganetespib in Combination with the mTOR Inhibitor Sirolimus for Patients with Recurrent or Refractory Sarcomas including Unresectable or Metastatic Malignant Peripheral Nerve Sheath Tumors

* 14-C-0007:
Phase II Trial of the Gamma-Secretase Inhibitor PF-03084014 in Adults with Desmoid Tumors/Aggressive Fibromatosis

* 14-C-0005:
A Pilot Study of Metformin in Patients with a Diagnosis of Li-Fraumeni Syndrome

* 14-C-0001:
Phase II Study of Axitinib (AG-013736) with Evaluation of the VEGF-pathway in Metastatic, Recurrent or Primary Unresectable Pheochromocytoma/Paraganglioma

* 14-AA-0187:
Dopamine Rhythms in Health and Addiction

* 14-AA-0120:
Neuroimaging Omega-3 and Reward in Adults with ADHD (NORAA) Trial

* 14-AA-0042:
A Novel Compound for Alcoholism Treatment: A Translational Strategy

* 13-N-0198:
Acute Effects of Exercise on Memory in Healthy and Brain-Injured Individuals

* 13-N-0127:
Increasing Self-Efficacy and Outcome Expectations For Exercise in Adults with Epilepsy: An Educational Motivation Intervention - E-MOVE

* 13-N-0104:
Natural History of Optic Neuritis

* 13-N-0008:
Sildenafil for the Treatment of Cerebrovascular Dysfunction during the Chronic Stage after Traumatic Brain Injury

* 13-M-0019:
Pilot Study to Extend the K-SADS-PL to Adolescents and Young Adults

* 13-I-0177:
Natural History Study of the Complications Associated with Allogeneic Hematopoietic Stem Cell Transplantations

* 13-I-0172:
Phase I Study of the Safety of Replication-Defective Herpes Simplex Virus-2 Vaccine, HSV529, in Adults Aged 18 to 40 Years With or Without HSV Infection

* 13-I-0141:
A Phase I Randomized, Double-Blind, Placebo-Controlled Study of a Multi-Antigen DNA Vaccine Prime Delivered by In Vivo Electroporation, rVSV Booster Vaccine in HIV-Infected Patients Who Began Antiretroviral Therapy During Acute/Early Infection

* 13-I-0081:
Phase 1 Study of Safety and Immunogenicity of Intranasal Ad4-H5-VTN in Ad4 Seronegative and Seropositive Volunteers

* 13-I-0077:
An Open-Label, Phase 1 Study to Assess the Safety and Tolerability of Bone Marrow Stromal Cell Infusion for the treatment of Moderate to Severe Inflammatory Bowel Disease

* 13-I-0062:
A Double Blind Randomized Placebo Controlled Study Examining the Effects of a Non-Absorbable (Rifaximin) Antibiotic on the Chronic Immune Activation Observed In HIV-infected Subjects

* 13-I-0029:
A Phase 1, Double-Blind, Placebo-Controlled, Single and Multiple Ascending Dose Study of the Safety, Tolerability, and Pharmacokinetics of AVI-7100 in Healthy Subjects

* 13-I-0020:
Elucidation of the Mucosal Immune Responses to Live Attenuated Influenza Vaccine In Healthy Adults

* 13-HG-0158:
Patient Perspectives and Simulated Clinical Interactions

* 13-EI-0124:
A Pilot Study of Nitisinone in the Treatment of Oculocutaneous Albinism, Type 1B

* 13-DK-0212:
Effect of a Eucaloric Ketogenic Diet on Energy Expenditure: A Pilot Study

* 13-DK-0150:
Unraveling the Mechanisms of Non-Response in Patients With and Without Cirrhosis Due to Chronic Hepatitis C

* 13-DK-0142:
The Physiology of Fatigue in Patients with Chronic Liver Disease

* 13-DK-0091:
Combination Therapy of Pegylated Interferon Alfa-2a and Tenofovir DF versus Tenofovir DF Monotherapy in HBeAg-Positive and HBeAg-Negative Chronic Hepatitis B

* 13-DK-0013:
Impact of Chronic Cold Exposure on Energy Metabolism in Humans

* 13-D-0014:
Bacterial Arrangement in Supragingival Biofilms

* 13-CH-0169:
Effects of Interrupting Sedentary Behavior on Metabolic and Cognitive Outcomes in Children

* 13-CH-0121:
A Pilot Study Assessing the Use of Continuous Subcutaneous Hydrocortisone Infusion in the Treatment of Congenital Adrenal Hyperplasia

* 13-CH-0001:
Intrathecal 2-Hydroxypropyl-B-Cyclodextrin in Patients with Niemann-Pick Disease, Type C1

* 13-CC-0178:
Prospective Pilot Observational Study Examining Cone Beam CT and CT Thermometry During Ablations

* 13-CC-0161:
A Description of the Oral Microbiome of Patients with Severe Aplastic Anemia

* 13-CC-0092:
Prospective Randomized Trial Comparing Navigation with 3D Roadmap vs. Conventional Angiography During Transarterial Embolization

* 13-C-0208:
Phase II Trial of Vandetanib (ZD6474, Caprelsa(R) in Children and Adults with Wild-Type Gastrointestinal Stromal Tumors

* 13-C-0153:
A Phase II Trial of Enzalutamide in Combination with PSA-TRICOM in Patients with Non-Metastatic Castration Sensitive Prostate Cancer

* 13-C-0152:
A Phase I Study of Autologous Activated Natural Killer (NK) Cells +/- rhIL15 in Children and Young Adults with Refractory Solid Tumors

* 13-C-0146:
A Randomized Phase II Trial Combining Vaccine Therapy with PROSTVAC /TRICOM and Enzalutamide vs. Enzalutamide Alone in Men with Metastatic Castration Resistant Prostate Cancer

* 13-C-0145:
Pilot Study of Eovist (Gadoxetate) Enhanced MRI for the Detection of Prostate Cancer

* 13-C-0128:
Collection of Saliva and/ or Peripheral Blood from Healthy Volunteers for Research

* 13-C-0120:
A Pilot Study of Tremelimumab - A Monoclonal Antibody against CTLA-4 in combination with Trans-Arterial Catheter Chemoembolization (TACE), Radiofrequency Ablation (RFA), or Cryoablation in Subjects with Hepatocellular Carcinoma (HCC) or Biliary Tract Ca

* 13-C-0114:
Phase II Trial of Surgical Resection and Heated Intraperitoneal Peritoneal Chemotherapy (HIPEC) for Adrenocortical Carcinoma

* 13-C-0106:
A Pivotal Multicenter Trial of Moxetumomab Pasudotox in Relapsed/ Refractory Hairy Cell Leukemia

* 13-C-0093:
Phase II Study in Patients with Metastatic Ocular Melanoma Using a Non-Myeloablative Lymphocyte Depleting Regimen of Chemotherapy Followed by Infusion of Autologous Tumor-Infiltrating Lymphocytes with or without High Dose Aldesleukin

* 13-C-0080:
A Phase I Trial of Weekly Indenoisoquinoline LMP400 in Adults with Relapsed Solid Tumors and Lymphomas

* 13-C-0069:
Multi-Center, Open-Label, Randomized Study of Anti-CCR4 Monoclonal Antibody KW-0761 or Investigator's Choice in Subjects with Previously Treated Adult T-cell Leukemia-Lymphoma (ATL)

* 13-C-0046:
A Phase I/II Trial of IL-13-PE in Patients with Treatment Refractory Malignancies with a Focus on Metastatic and Locally Advanced Adrenocortical Carcinoma

* 13-C-0045:
A Phase 1 Study of Recombinant Human IL15 (rhIL15) in Adults with Advanced Solid Tumors: Melanoma, Renal Cell, Non-Small Cell Lung and Head and Neck Cancer

* 13-C-0042:
A Phase I Study of XL184 (Cabozantinib, IND# 116059) in Children and Adolescents with Recurrent or Refractory Solid Tumors, Including CNS Tumors

* 13-C-0009:
A Multicenter Randomized Phase II Study of NPC-1C in Combination with Gemcitabineand nab-Paclitaxel versus Gemcitabine and nab-Paclitaxel Alone in Patients with Metastatic or Locally Advanced Pancreatic Cancer Previously Treated with FOLFIRINOX

* 13-AR-0086:
A Pilot Open-Label Study of Rilonacept (Arcalyst) in the Deficiency of the Interleukin-1 Receptor Antagonist (DIRA)

* 13-AR-0005:
A Phase 1b, Randomized, Double-Blind, Placebo Controlled Study with an Open Label Extension to Evaluate the Safety and Tolerability of Omalizumab, A Humanized IgG1 Monoclonal Antibody in Patients with Lupus (STOP LUPUS)

* 13-AA-0061:
OPRM1 A118G SNP Effect on Striatal Dopamine Response to an IV Opiate

* 13-AA-0043:
Effects of Ghrelin on Alcohol Administration in Non-Treatment Seeking Heavy Drinkers

* 13-AA-0040:
A Double-Blind, Placebo-Controlled, Randomized Human Laboratory Pilot Study of Baclofen in Anxious Alcoholics

* 12-HG-0207:
A Phase 1 Randomized, Placebo-Controlled, Double-Blind, Escalating Single-Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ManNAc in Subjects with GNE myopathy or Hereditary Inclusion Body Myopathy (HIBM)

* 12-HG-0147:
Genetic Studies of Non-Alcoholic Fatty Liver Disease

* 12-H-0146:
Clofarabine Followed by Lenalidomide for Treatment of High Risk Myelodysplastic Syndromes and Acute Myeloid Leukemia

* 12-H-0133:
A Randomized, Double-Blind, Placebo Controlled Study of Liposomal Amikacin for Inhalation (Arikayce ) in Patients with Recalcitrant Nontuberculous Mycobacterial Lung Disease

* 12-H-0124:
Microvascular and Cardiac Dysfunction in Sickle Cell Disease

* 12-H-0103:
Characterization of Innate Immune Responses to AS03 Adjuvanted H5N1 Vaccine Compared to Non-adjuvanted H5N1 Vaccine

* 12-H-0101:
Measurement of the Reactive Hyperemia Index in Sickle Cell Patients During Pain Crisis and After Recovery

* 12-H-0092:
An Intravenous, Open-Label, Single-Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of rhLCAT in Patients with Stable Coronary Artery Disease

* 12-H-0084:
Metabolic Phenotyping of Subjects with Mutations Associated with Hereditary Parkinson's Disease

* 12-H-0078:
Preliminary Assessment of Direct Intra-Myocardial Injection of Autologous Bone Marrow-derived Stromal Cells on Patients Undergoing Revascularization for CAD with Depressed Left Ventricular Function

* 12-H-0070:
A Pilot Two-Step Phase II Study of the Oral Gold Compound Auranofin in Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)/Prolymphocytic Lymphoma (PLL)

* 12-H-0052:
Prospective Randomized Trial on Radiation Dose Estimates of CT Angiography in Patients Applying Iterative Image Reconstruction Techniques

* 12-H-0035:
A Phase II Study of PCI-32765 for Patients with Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL) Who Need Therapy and are Older than 65 or have a 17p Deletion

* 12-H-0010:
A Phase I Study of Bone Marrow Stromal Cell Infusions to Treat Acute Graft Versus Host Disease, Marrow Failure and Tissue Injury After Allogeneic Stem Cell Transplantation

* 12-E-0190:
The Role of Functionally Relevant Cyclooxygenase-2 (COX-2) Gene Single Nucleotide Polymorphisms -765G>C and 8473T>C in Lymphocyte Differentiation

* 12-DK-0071:
Combination Entecavir and Peginterferon Therapy in HBeAG-Postive Immune-Tolerant Adults with Chronic Hepatitis B

* 12-DK-0046:
Treatment of Chronic Delta Hepatitis with Lonafarnib

* 12-CH-0212:
Oogonial Stem Cell Isolation in Ovarian Insufficiency Patients

* 12-CH-0062:
Investigations into ISCU Myopathy or Iron Sulfur Scaffold U Protein Myopathy

* 12-CH-0016:
Bone Marrow Cell Engraftment of the Uterus and Genetic Studies of Reproductive Functioning

* 12-CH-0011:
Non-Invasive Study of Brain Connectivity Using Combined EEG and NIRS

* 12-CC-0145:
Pilot Study of Yoga as Self-Care for Arthritis in Minority Communities

* 12-CC-0125:
Detection of Respiratory Viruses in Upper and Lower Respiratory Tract Specimens Using a Rapid Multiplex PCR

* 12-C-0208:
Phase 1 Dose Escalation Study of Sorafenib and Irinotecan Combination Therapy in Pediatric Patients with Relapsed or Refractory Solid Tumors

* 12-C-0205:
A Phase II Study of Cabozantinib (XL184) in Patients With Advanced/Metastatic Urothelial Carcinoma

* 12-C-0197:
A Randomized Phase 2 Single-Center Study of Pomalidomide for Chronic GvHD

* 12-C-0192:
Lenalidomide Maintenance Therapy in Multiple Myeloma: A Phase II Clinical and Biomarker Study

* 12-C-0177:
A Phase I and Pharmacokinetic Single-Agent Study of Romidepsin in Patients With Lymphomas, Chronic Lymphocytic Leukemia, and Select Solid Tumors, and Varying Degrees of Liver Dysfunction

* 12-C-0170:
A Phase 1B Study to Evaluate the Safety and Induction of Immune Response of CRS 207 in Combination with Pemetrexed and Cisplatin as Front-Line Therapy in Adults with Malignant Pleural Mesothelioma

* 12-C-0160:
Validation of the English Version of the Pain Interference Index and the Pain Rating Scale in Children, Adolescents, and Young Adults with Chronic Illness and their Parents

* 12-C-0151:
Phase II Evaluation of Mithramycin, an Inhibitor of Cancer Stem Cell Signaling, in Patients with Malignancies Involving Lungs, Esophagus, Pleura, or Mediastinum

* 12-C-0148:
SARC016: Phase 2 Study of the mTOR Inhibitor Everolimus in Combination with Bevacizumab in Patients with Sporadic and Neurofibromatosis Type 1 (NF1) Related Refractory Malignant Peripheral Nerve Sheath Tumors

* 12-C-0136:
A Phase II Randomized Trial of Lenalidomide (NSC # 703813, IND # 70116) in Pediatric Patients with Recurrent, Refractory or Progressive Juvenile Pilocytic Astrocytomas and Optic Pathway Gliomas

* 12-C-0135:
Phase I/II Trial of Mithramycin in Children and Adults with Refractory Extracranial Solid Tumors (Phase I) or Ewing Sarcoma and EWSFLI1 Fusion Transcript (Phase II)

* 12-C-0118:
A Phase II Study of Sunitinib in Patients with Advanced Relapsed or Refractory Thymoma or Thymic Carcinoma with at Least One Prior Line of Platinum-Based Systemic Chemotherapy

* 12-C-0116:
A Phase II Study of Lymphodepletion Followed by Autologous Tumor-Infiltrating Lymphocytes and High-Dose Aldesleukin for Human Papillomavirus-Associated Cancers

* 12-C-0112:
Phase I Study of T Cells Expressing an Anti-CD19 Chimeric Receptor in Children and Young Adults with B Cell Malignancies

* 12-C-0107:
Carfilzomib, Lenalidomide, and Dexamethasone in High-Risk Smoldering Multiple Myeloma: A Clinical and Correlative Study

* 12-C-0081:
Phase I/II Study of Cediranib and Olaparib in Combination for Treatment of Recurrent Papillary-Serous Ovarian, Fallopian Tube, or Peritoneal Cancer or for Treatment of Recurrent Triple-Negative Breast Cancer

* 12-C-0079:
A Phase II Multicenter Study of AMG 386 and Abiraterone in Metastatic Castration Resistant Prostate Cancer

* 12-C-0074:
Mobilization and Collection of Autologous Stem Cell for Transplantation (ASCT) for Plasma Cell Myeloma (PCM)

* 12-C-0068:
A Randomized Double-Blind Pilot Study of Topical Clobetasol 0.05% Oral Rinse for Oral Chronic Graft-Versus-Host-Disease

* 12-C-0056:
An Open Label Phase I Study to Evaluate the Safety and Tolerability of GI-6301 Vaccine Consisting of Whole, Heat-Killed Recombinant Saccharomyces Cerevisiae (Yeast) Genetically Modified to Express Brachyury Protein in Adults with Solid Tumors

* 12-C-0009:
Phase Ib Study of the Combination of Pazopanib, an Oral VEGFR Inhibitor, and ARQ 197 (Tivantinib), an Oral MET Inhibitor, in Patients with Refractory Advanced Solid Tumors

* 12-C-0008:
An Open Label Phase I Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Maximum Tolerated Dose of the Antimesothelin Antibody Drug Conjugate BAY 94-9343 in Subjects with Advanced Solid Tumors

* 12-C-0003:
Phase I/II Trial of Yttrium-90-labeled Daclizumab (anti-CD25) Radioimmunotherapy with High-dose BEAM Chemotherapy and Autologous Hematopoietic Stem Cell Rescue in Recurrent and Refractory Hodgkin s Lymphoma

* 12-AG-0019:
Age-Associated Changes in Regional Adiposity and Novel Cardiovascular Risk Factors

* 11-N-0261:
Evaluation of Skeletal Muscle, Cardiac, and Diaphragm Imaging Biomarkers for GSK2402968 Effects in Ambulatory Boys with Duchenne Muscular Dystrophy

* 11-N-0210:
NIB Repository Protocol

* 11-N-0171:
Effect of Functional Exercise in Patients with Spinal and Bulbar Muscular Atrophy

* 11-M-0144:
Markers of Autism Spectrum Disorders in At-Risk Toddlers: A Pilot Study

* 11-I-0259:
Phase 1 Study of Safety and Immunogenicity of Ad4-H5-VTN in Ad4 Seronegative and Seropositive Volunteers

* 11-I-0057:
Effect of Interferon Alpha 2b Intensification on HIV-1 Residual Viremia in Individuals Suppressed on Antiretroviral Therapy

* 11-I-0031:
A Randomized Double-Blind Study Comparing Oseltamivir Versus Placebo for the Treatment of Influenza in Low Risk Adults

* 11-HG-0238:
Weight Management Interactions in a Virtual Clinical Environment

* 11-H-0268:
The Safety and the Tolerability of Ultra Low Dose Interleukin-2 in Healthy Volunteers

* 11-H-0252:
Exploratory Studies of Psychophysical Pain Phenotyping and Genetic Variability in Sickle Cell Disease

* 11-H-0209:
Male Hormones for Telomere Related Diseases

* 11-H-0184:
An Extended Phase 2 Study of Decitabine in Subjects with High Risk Sickle Cell Disease

* 11-H-0121:
A Phase I Study of the Use of Topical Sodium Nitrite for Chronic Leg Ulcers in Adult Patients with Hemolytic Disorders

* 11-H-0092:
Effects of Systemically Administered Hydrocortisone on the Human Immunome in Healthy Volunteers

* 11-H-0046:
Cross-Sectional Characterization of Idiopathic Bronchiectasis

* 11-DK-0256:
Pharmacokinetic and Pharmacodynamic Studies of Liothyronine. A Study on the Metabolic Effects of Thyroid Hormone

* 11-DK-0151:
Withdrawal of Therapy After Long-Term Oral Nucleos(t)ide Analogue Treatment in Patients with Chronic Hepatitis B

* 11-D-0094:
A Randomized Within-Subject, Double-Blind, Placebo-Controlled Study of Dexamethasone Irrigation of the Parotid Glands in Primary Sj(SqrRoot)(Delta)gren's Syndrome Subjects

* 11-CH-0119:
Adrenal Hyperplasia Among Young Patients with Polycystic Ovarian Syndrome

* 11-CH-0078:
Evaluation of Cortisol Resistance in Young Endurance-Trained and Elderly Men

* 11-CC-0265:
A Pilot Study to Examine Physiological and Clinical markers of Chronic Stress in Caregivers of Allogeneic Hematopoietic Stem Cell Transplant (HSCT) Recipients

* 11-CC-0246:
Characteristics and Mechanism of Childhood-Onset Hemidystonia

* 11-CC-0201:
The Effect of Music Listening on the Amount of Opioids Used in Surgical Intensive Care Patients

* 11-CC-0088:
Effect of Aerobic Exercise Training on Cardiorespiratory Function in Patients with Traumatic Brain Injury

* 11-CC-0083:
Beyond Intuition: Quantifying and Understanding the Signs and Symptoms of Fever

* 11-C-0262:
A Randomized, Double-Blind, Phase 3 Efficacy Trial of PROSTVAC-V/F plus or minus GM-CSF in Men with Asymptomatic or Minimally Symptomatic Metastatic, Castrate-Resistant Prostate Cancer

* 11-C-0247:
A Randomized Phase II Study of Tecemotide in Combination with Standard Androgen Deprivation Therapy and Radiation Therapy for untreated, intermediate and High Risk Prostate Cancer Patients

* 11-C-0232:
A Phase I/II Study of the Histone Deacetylase (HDAC) Inhibitor LBH589 (Panobinostat) in Combination with mTOR Inhibitor RAD001 (Everolimus) in Patients with Relapsed Multiple Myeloma or Lymphoma

* 11-C-0226:
Targeted Theraphy of Bronchiolitis Obliterans Syndrome (BOS)

* 11-C-0221:
Carfilzomib, Lenalidomide, and Dexamethasone in Newly Diagnosed Multiple Myeloma: Clinical and Correlative Phase II Study

* 11-C-0162:
A Multicenter, Open-Label, Phase 2, Safety and Efficacy Study of the Bruton's Tyrosine Kinase (Btk) Inhibitor, PCI-32765, in Subjects with Relapsed or Refractory De Novo Diffuse Large B-Cell Lymphoma

* 11-C-0160:
A Pilot/ Phase 2 Study of Pentostatin Plus Cyclophosphamide Immune Depletion to Decrease Immunogenicity of SS1P in Patients with Mesothelioma, Lung Cancer or Pancreatic Cancer

* 11-C-0158:
MR Image Guided Focal Therapy in Prostate Cancer

* 11-C-0150:
Phase I Study of the Hsp90 Inhibitor, PU-H71, in Patients with Refractory Solid Tumors and Low-Grade Non-Hodgkin's Lymphoma

* 11-C-0140:
A Phase I Study of Gemcitabine, Carboplatin and Lenalidomide (GCL) for Treatment of Patients with Advanced/Metastatic Urothelial Carcinoma (UC) and Other Solid Tumors

* 11-C-0136:
Multi-Institutional Prospective Pilot Study of Lupron to Enhance Lymphocyte Immune Reconstitution Following Allogeneic Bone Marrow Transplantation in Post-Pubertal Children and Adults with Molecular Imaging Evaluation

* 11-C-0132:
Understanding the Psychosocial Needs of Parents Who Have Lost a Child to Cancer

* 11-C-0123:
Prospective Randomized Study of Cell Transfer Therapy for Metastatic Melanoma Using Tumor Infiltrating Lymphocytes Plus IL-2 Following Non-Myeloablative Lymphocyte Depleting Chemo Regimen Alone or in Conjunction with 12Gy Total Body Irradiation (TBI)

* 11-C-0111:
Adjuvant Allogeneic Tumor Cell Vaccine with Metronomic Oral Cyclophosphamide and Celecoxib in Patients Undergoing Resection of Sarcomas, Melanomas, Germ Cell Tumors, or Epithelial Malignancies Metastatic to Lungs, Pleura, or Mediastinum

* 11-C-0102:
A Phase I/II Study of TRC105 in Combination with Sorafenib in Hepatocellular Carcinoma (HCC)

* 11-C-0077:
Phase II Study of Oral PHA-848125AC in Patients with Malignant Thymoma Previously Treated with Multiple Lines of Chemotherapy

* 11-C-0073:
A Phase I Study of NK Cell Infusion Following Allogeneic Peripheral Blood Stem Cell Transplantation from Related or Matched Unrelated Donors in Pediatric Patients with Hematologic Malignancies

* 11-C-0038:
A Phase 2 Study of Vorinostat in Subjects with Locally Advanced, Recurrent or Metastatic Adenoid Cystic Carcinoma (ACC) (IND 71976)

* 11-C-0033:
Extended Follow-up of High Ovarian Cancer Risk Cohort from 02-C-0268 (GOG-199)

* 11-C-0029:
Phase I Study of the HSP-90 Inhibitor, AT13387, in Adults with Refractory Solid Tumors

* 11-C-0027:
A Phase I/II Trial of Crolibulin (EPC2407) plus Cisplatin in Adults with Solid Tumors with a Focus on Anaplastic Thyroid Cancer (ATC)

* 11-C-0024:
A Phase II Trial of IPH2101 (Anti-KIR) in Smoldering Multiple Myeloma (SMM)

* 11-C-0022:
A Pharmacokinetic/Pharmacodynamic Study with a Phase I Run-In with a PARP Inhibitor (Olaparib) in Combination with Carboplatin for Refractory or Recurrent Women's Cancers

* 11-C-0021:
A Pilot Study of F-18 Sodium Fluoride PET/CT for Metastatic Burden Qualification in Prostate Cancer

* 10-N-0125:
Investigating Mechanism of Action of DAC HYP in the Treatment of High-Inflammatory Multiple Sclerosis (MS)

* 10-N-0009:
Physiological Investigations of Movement Disorders

* 10-N-0003:
Recording and Modulation of Neuronal Mechanisms During Operant Conditioning: A MEG Study

* 10-I-0210:
A Randomized Double-Blind Phase 2 Study Comparing the Efficacy, Safety, and Tolerability of Combination Antivirals (Amantadine, Ribavirin, Oseltamivir versus Oseltamivir for the Treatment of Influenza in Adults at Risk for Complications

* 10-I-0205:
Assessment of Alterations in Immune Function During Pregnancy and Post Parturition

* 10-I-0139:
Searching for Persistence of Infection in Lyme Disease

* 10-I-0101:
A Randomized, Placebo-controlled, Double-Blind Pilot Study of Single-Dose Humanized Anti-IL5 Antibody (Reslizumab) for the Reduction of Eosinophilia Following Diethylcarbamazine Treatment of Loa Loa Infection

* 10-I-0043:
A Randomized, Open-Label, Phase 2, Multicenter Safety and Exploratory Efficacy Study of Investigational anti-Influenza Immune Plasma for the Treatment of Influenza

* 10-HG-0076:
Mothers' Thoughts About What Their Children Eat

* 10-H-0176:
Cyclophosphamide Plus Cyclosporine in Treatment-Naive Severe Aplastic Anemia

* 10-H-0165:
Effects of Rosuvastatin on the Immune System in Healthy Volunteers with Normal Cholesterol

* 10-H-0162:
Collection of Blood, Bone Marrow, Leukapheresis, and Tissue Biopsy Samples from Patients and their Family Members for Center for Human Immunology, Autoimmunity, and Inflammatory Diseases (CHI) Laboratory Research Studies

* 10-H-0141:
A Phase II Study of Ofatumumab-Based Induction Chemoimmunotheraphy Followed by Consolidation Ofatumumab Immunotherapy in Previously Untreated Patients with Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

* 10-H-0083:
A Phase I Trial of Safety and Immunogenicity of Gardasil Vaccination Post Stem Cell Transplantation in Patients with and Without Immunosuppression

* 10-E-0134:
Effect of SNPs in p53 and p53 Response Elements on the Inflammatory Response to DNA Damage

* 10-DK-0187:
Duration of Long-Term Immunity After Hepatitis B Virus Immunization

* 10-DK-0135:
Role of Donor Genetics and Recipient Genetics in Kidney Transplant Outcomes

* 10-DK-0064:
Effects of Caloric Restriction Alone versus Postoperative Caloric Restriction Following Bariatric Surgery on Glucose Metabolism in Patients with Diabetes Mellitus

* 10-D-0180:
A Pilot Trial Targeting mTOR as a Novel Mechanism-Based Neoadjuvant Therapy for Head and Neck Cancer

* 10-D-0020:
The Molecular Anatomy of Oral Wound Healing

* 10-CH-0022:
Exome Sequencing in Autistic Spectrum Disorder Patients with Altered Cholesterol Homeostasis

* 10-CC-0217:
A Comparison of Methods for Assisting Needle Angle Selection During Image-Guided Tissue Biopsy

* 10-CC-0214:
The RIGHT study: Risk stratification with Image Guidance of HMG coa reductase inhibitor Therapy

* 10-CC-0153:
Noninvasive Imaging of Heart Failure

* 10-CC-0150:
Effects of Rapid-Resisted Exercise on Ambulatory Adults with Traumatic Brain Injury

* 10-CC-0149:
Comparing Expectorated and Induced Sputum and Pharyngeal Swabs for Cultures, AFB Smears, and Cytokines in Pulmonary Nontuberculous Mycobacterial Infection

* 10-CC-0073:
Physical, Functional and Neurological Effects of Two Lower Extremity Exercise Programs in Children with Cerebral Palsy

* 10-C-0219:
A Phase I Trial of Lenalidomide and Radiotherapy in Children with Diffuse Intrinsic Pontine Gliomas and High-grade Gliomas

* 10-C-0218:
Randomized Phase II Study of AZD6244 MEK-Inhibitor with Erlotinib in KRAS Wild Type and KRAS Mutant Advanced Non-Small Cell Lung Cancer

* 10-C-0189:
A Phase 1, Dose Escalation Study of MGAH22 (Fc-Optimized Chimeric Anti-HER2 Monoclonal Antibody) in Patients with Refractory HER2 Positive Breast Cancer and Patients with Other HER2 Positive Carcinomas for Whom no Standard Therapy is Available

* 10-C-0181:
Phase 1 Dose-Escalation Study of Bruton s Tyrosine Kinase (Btk) Inhibitor PCI-32765 in Recurrent B Cell Lymphoma

* 10-C-0146:
Phase II Study of IMC-A12 in Patients with Mesothelioma Who Have Been Previously Treated with Chemotherapy

* 10-C-0138:
Allogeneic Tumor Cell Vaccine with Metronomic Oral Cyclophosphamide and Celecoxib as Adjuvant Therapy for Lung and Esophageal Cancers, Thymic Neoplasms, Thoracic Sarcomas, and Malignant Pleural Mesotheliomas

* 10-C-0096:
Natural History Study of Monoclonal Gammopathy of Undetermined Significance (MGUS) and Smoldering Myeloma (SMM)

* 10-C-0077:
A Phase 1/2 Study of PXD101 (Belinostat) in Combination with Cisplatin, Doxorubicin and Cyclophosphamide in the First Line Treatment of Advanced or Recurrent Thymic Malignancies

* 10-C-0056:
A Phase I Study of Indenoisoquinolines LMP400 and LMP776 in Adults With Relapsed Solid Tumors and Lymphomas

* 10-C-0054:
Administration of Anti-CD19-Chimeric-Antigen-Receptor-Transduced T-cells from the Original Transplant Donor to Patients with Recurrent or Persistent B-Cell Malignancies After Allogeneic Stem Cell Transplantation

* 10-C-0050:
A Randomized Phase II Study of Rituximab with ABVD Versus Standard ABVD for Subjects with Advanced-Stage Classical Hodgkin Lymphoma with Poor Risk Features (IPS score >2)

* 10-C-0019:
Development and Validation of a Symptom Scale for Children with Chronic Graft-Versus-Host Disease

* 10-C-0011:
Phase II Trial of Alemtuzumab (Campath) and Dose-Adjusted EPOCH-Rituximab (DA-EPOCH-R) in Relapsed or Refractory Diffuse Large B-Cell and Hodgkin Lymphomas

* 10-AG-0423:
A Pilot Study of Exendin-4 in Alzheimer s Disease

* 10-AA-0046:
Effects of Corticotropin-Releasing Hormone Receptor 1 (CRH1) Antagonism on Stress-Induced Craving in Alcoholic Women with High Anxiety: an Experimental Medicine Study

* 09-NR-0131:
Fatigue in Healthy Individuals

* 09-N-0197:
Double Blind Placebo-Controlled Phase I/II Clinical Trial of Idebenone in Patients with Primary Progressive Multiple Sclerosis

* 09-N-0039:
A Phase I Study of the Intrathecal Administration of Resiniferatoxin for Treating Severe Refractory Pain Associated with Advanced Cancer

* 09-N-0010:
Biomarkers of Risk of Parkinson Disease

* 09-M-0198:
Screening and Evaluation of Patients with Signs and Symptoms of Alzheimer's Disease

* 09-M-0194:
Characterizing Lone Parenting: A Multi-Institutional Pilot Study of the Perceptions of Support and Perceived Stress of Lone Parents of Children with Cancer

* 09-M-0177:
CO2 Inhalation and Risk for Panic Disorder

* 09-M-0022:
The Use of a Distress Thermometer in a Pediatric Research Setting: An Exploratory, Pilot Study

* 09-I-0226:
A Pilot Study for Collection of Anti-Influenza A Immune Plasma

* 09-I-0163:
HVTN 505: Ph 2 RPCT Test-of-Concept Trial to Eval Safety/Effect Post-HIV Acquisition Viremia of Multiclade HIV-1 DNA Plasmid Vaccine F/B Multiclade HIV-1 Recombinant Adenoviral Vector Vaccine in HIV-Uninfected, Adenovirus Type 5 Neutralizing AB Negative

* 09-I-0108:
Strategic Timing of AntiRetroviral Treatment (START)

* 09-HG-0009:
Participant Reactions to Disease Risk Information

* 09-H-0244:
A Randomized, Placebo-Controlled, Double-Blind Pilot Study of Pioglitazone Hydrochloride in Severe, Refractory Asthma

* 09-H-0239:
Cellular and Molecular Characterization of the Immune Response in Healthy NIH Employees at Baseline, and After Immunization with the H1N1 or Seasonal Influenza Vaccines

* 09-H-0229:
Collection of Blood, Bone Marrow, Skin Biopsies and Buccal Mucosa Samples from Healthy Volunteers for Center for Human Immunology, Autoimmunity, and Inflammatory Diseases (CHI) Protocols Laboratory Research Studies

* 09-H-0225:
Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Severe Congenital Anemias Including Sickle Cell Disease and Beta-Thalassemia

* 09-H-0215:
Multi Center Combined Non-invasive Coronary Angiography and Myocardial Perfusion Imaging using 320-Detector Computed Tomography

* 09-H-0201:
Screening Protocol for Subjects being Evaluated for Center for Human Immunology, Autoimmunity, and Inflammatory Diseases (CHI) Protocols

* 09-H-0183:
Horse ATG/CsA in Aplastic Anemia Patients Unresponsive to or with a Suboptimal Response to Rabbit ATG/CsA Treatment

* 09-H-0164:
Comparison of Cardiac Computed Tomography and Vasodilator Stress Magnetic Resonance Imaging Perfusion in Patients with Prior Equivocal Stress Test for Detection of Coronary Artery Disease

* 09-H-0154:
A Pilot Study of a Thrombopoietin-Receptor Agonist (TPO-R Agonist), Eltrombopag, in Aplastic Anemia Patients with Immunosuppressive-Therapy Refractory Thrombocytopenia

* 09-H-0087:
Mismatched Donor Lymphocyte Infusions for Relapsed Disease Following Allogeneic Stem Cell Transplantation

* 09-DK-0081:
Selective Reduction of Dietary Carbohydrate Versus Fat: Effects on Metabolism, Endocrine Physiology, Brain Activity and Reward Circuitry

* 09-DK-0055:
Assessment of the Effects of a DPP-4 Inhibitor (Sitagliptin) Januvia on Immune Function in Healthy Individuals

* 09-CC-0217:
Vasti Control of Patellofemoral Kinematics in Asymptomatic Volunteers

* 09-C-0224:
Pilot Study of Radiation-Enhanced Allogeneic Cell Therapy for Progressive Hematologic Malignancy After Allogeneic Hematopoietic Stem Cell Transplantation

* 09-C-0195:
A Phase 2 Trial of Bevacizumab, Lenalidomide, Docetaxel, and Prednisone (ART-P) for Treatment of Metastatic Castrate-Resistant Prostate Cancer

* 09-C-0173:
A Phase I Study of Belinostat in Combination with Cisplatin and Etoposide in Adults with a Focus on Small Cell Lung Cancer and other Cancers of Neuroendocrine Origin

* 09-C-0139:
A Pilot Study of Vaccination with Epitope-Enhanced TARP Peptide and TARP Peptide-Pulsed Dendritic Cells in the Treatment of Stage D0 Prostate Cancer

* 09-C-0130:
Pilot Study of Liposomal Doxorubicin Combined with Bevacizumab Followed by Bevacizumab Monotherapy in Adults with Advanced Kaposi s Sarcoma

* 09-C-0111:
A Phase 1, Dose Escalation Study of the Safety, Tolerability and Pharmacokinetics of Intravenous Dimethane Sulfonate (DMS612, NSC 281612) in Advanced Malignancies

* 09-C-0104:
A Randomized, Double-Blinded, Placebo-Controlled, Multi-Institutional, Cross-Over, Phase II.5 Study of Saracatinib (AZD0530), a Selective Src Kinase Inhibitor, In Patients with Recurrent Osteosarcoma Localized to the Lung

* 09-C-0103:
Prospective Analysis of Genotypes in Adults Undergoing Therapy for Lung Cancer

* 09-C-0096:
Pilot and Feasibility Study of Reduced-Intensity Hematopoietic Stem Cell Transplant for Patients with GATA2 Mutations

* 09-C-0089:
A Targeted Ph I/II Trial of ZD6474 (Vandetanib; CAPRELSA) Plus the Proteasome Inhibitor, Bortezomib (Velcade ), in Adults with Solid Tumors with a Focus on Hereditary or Sporadic, Locally Advanced or Metastatic Medullary Thyroid Ca (MTC)

* 09-C-0082:
Assessment of the Safety and Feasibility of Administering T cells Expressing an anti-CD19 Chimeric Antigen Receptor to Patients with B-cell Lymphoma

* 09-C-0065:
Phase 1 Trial of Siplizumab and Dose-Adjusted EPOCH-Rituximab (DA-EPOCH-R) in T and NK-Cell Lymphomas

* 09-C-0057:
A Phase II Multi-Center Study of Bevacizumab in Combination with Ixabepilone in Subjects with Advanced Renal Cell Carcinoma

* 09-C-0054:
A Group Wide Biology and Banking Study for Phase II Study of R1507

* 09-C-0025:
Phase II Trial of LMB-2, Fludarabine and Cyclophosphamide for Adult T-Cell Leukemia

* 09-C-0024:
A Phase I Study of Quadrivalent Human Papilloma Virus (HPV) (Types 6, 11, 16, 18) Recombinant Vaccine in HIV-Infected and HIV-Negative Pre-Adolescents, Adolescents and Young Adults

* 09-C-0019:
A Phase I Study of Dasatinib in Combination with Bevacizumab in Advanced Solid Tumors

* 08-N-0044:
A Prospective Natural History Study of Patients with Neurofibromatosis Type 2 (NF2)

* 08-M-0066:
PET Evaluation of Brain Peripheral Benzodiazepine Receptors using [11C]PBR28 in Neurological Disorders

* 08-M-0052:
fMRI Investigation of Cortical Reorganization and Phantom Limb Pain Following Amputation

* 08-HG-0224:
Clinical and Genetic Studies of VACTERL Association

* 08-HG-0122:
Patient-Provider Communication and Interaction in a Virtual Clinical Setting

* 08-H-0177:
Multicenter International Lymphangioleiomyomatosis Efficacy of Sirolimus Trial (The MILES Trial)

* 08-EI-0169:
Evaluation and Treatment Protocol for Potential Research Participants with Ocular Diseases

* 08-DK-0173:
A Trial of Segmental Stiffening Wires to Improve the Efficiency and Patient Tolerability of Colonoscopy

* 08-DK-0165:
Thyroid Hormones Homeostasis and Energy Metabolism Changes During Stimulation of Endogenously Secreted Bile Acids (BAs)

* 08-DK-0149:
High Dose Ribavirin in Combination with Peginterferon for Patients with Chronic Hepatitis C Genotype 1 Infection Who Have Failed to Respond or Relapsed after Standard Therapy

* 08-CC-0220:
A Phase II Clinical Trial to Determine the Effectiveness of Problem Solving Education in Caregivers and Patients during Allogeneic HSCT

* 08-CC-0133:
The NIH Exercise Therapy for Advanced Lung Disease Trials: Response and Adaptation to Aerobic Exercise in Patients with Pulmonary Hypertension: Initial Studies for Establishing Guidelines

* 08-CC-0032:
Parental Permission and Adolescent Assent and Decision Making in Clinical Research

* 08-C-0148:
A Pilot Study of Imatinib Mesylate in Children and Adults with Sclerotic Skin Changes of Chronic Graft-Versus-Host Disease

* 08-C-0130:
A Phase II Trial of Peginterferon Alpha-2b (PEG-Intron) for Neurofibromatosis Type 1 Related Unresectable, Symptomatic or Life-Threatening Plexiform Neurofibromas

* 08-C-0097:
Multi-Institutional Prospective Phase II Study of Montelukast for the Treatment of Bronchiolitis Obliterans Following Allogeneic or Autologous Stem Cell Transplantation in Children and Adults

* 08-C-0092:
A Phase I Study with an Expansion Cohort of the PARP Inhibitor AZD2281 (KU-0059436) Combined with Carboplatin in Breast and Ovarian Cancer in BRCA1/2 Mutation Carriers (Familial Breast and Ovarian Cancer) and Sporadic Triple Negative Breast Cancer and Ov

* 08-C-0088:
Low Intensity Allogeneic Hematopoietic Stem Cell Transplantation Therapy of Metastatic Renal Cell Carcinoma using Early and Multiple Donor Lymphocyte Infusions Consisting of Sirolimus-Generated Donor Th2 Cells

* 08-C-0026:
A Phase 1, Single Center, Dose-Escalation Study of SS1(dsFv)PE38 Administered Concurrently with Pemetrexed and Cisplatin in Subjects with Unresectable Malignant Epithelial Pleural Mesothelioma

* 08-C-0020:
A Phase 2 Study of ZD6474 (Vandetanib) in Patients with Von Hippel Lindau Disease and Renal Tumors

* 08-AR-0008:
Insulin Resistance and Atherosclerosis in a Sample of Women with Systemic Lupus Erythematosus

* 07-H-0177:
Treatment of Pulmonary Hypertension and Sickle Cell Disease with Sildenafil Therapy

* 07-H-0159:
Efficacy of WT1 and PRI Peptide Vaccination for Patients with Low Risk Myeloid Malignancies

* 07-H-0136:
Selective Depletion of Alloreacting T Cells Using a Photodepletion Technique to Prevent GVHD after HLA-Matched Peripheral Blood Stem Cell Transplantation for Subjects with Hematologic Malignancies

* 07-H-0104:
A Phase II Study of Lenalidomide Revlimid in Previously Treated Patients with Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

* 07-EI-0213:
Laboratory of Immunology/National Eye Institute Repository

* 07-E-0012:
Rituximab in the Treatment of Refractory Adult and Juvenile Dermatomyositis (DM) and Adult Polymyositis (PM)

* 07-DK-0219:
A Nutrigenomics Intervention for the Study of the Role of Dietary Sitosterol on Lipid, Glucose and Energy Metabolism

* 07-DK-0202:
Thyroid Hormones Homeostasis and Energy Metabolism Changes During Exposure to Cold Temperature in Humans

* 07-D-0016:
Effects of PTH Replacement on Bone in Hypoparathyroidism

* 07-CH-0008:
Prospective, Open-Label, Multicenter, International Study of Mifepristone for Symptomatic Treatment of Cushing's Syndrome Caused by Ectopic Adrenal Corticotrophin Hormone (ACTH) Secretion

* 07-CC-0011:
Hypnosis as a Pain and Symptom Management Strategy in Patients with Sickle Cell Disease

* 07-C-0206:
A Pilot Study of Tumor Vaccination and/or R-hIL-7 Following Standard Multimodality Therapy in Patients with High Risk Pediatric Solid Tumors

* 07-C-0195:
Phase II Trial of Targeted Immune-Depleting Chemotherapy and Reduced-Intensity Allogeneic Hematopoietic Stem Cell Transplantation Using 8/8 and 7/8 HLA-matched Unrelated Donors and Utilizing Two Graft-versus-Host Disease Prophylaxis Regimens for the Trea

* 07-C-0189:
Phase I/II Trial of Vandetanib (ZD6474, ZACTIMA) in Children and Adolescents with Hereditary Medullary Thyroid Carcinoma

* 07-C-0130:
A Phase 1, Multicenter, Dose-Escalation Study of CAT-8015 in Patients with Relapsed or Refractory Hairy Cell Leukemia (HCL)

* 07-C-0121:
A Phase 2 Study of the C-Met RTK Inhibitor Foretinib (Formerly GSK 1363089) in Subjects with Papillary Renal-Cell Carcinoma (PRC)

* 07-C-0107:
A Randomized Phase II Trial Combining Vaccine Therapy with PROSTVAC/TRICOM and Flutamide vs. Flutamide Alone in Men with Androgen Insensitive, Non-Metastatic (D0.5) Prostate Cancer

* 07-C-0101:
A Phase 0 Trial of (111)Indium CHX-A DTPA Trastuzumab Imaging in Cancer

* 07-C-0081:
A Phase I/II Study of Flavopiridol in Relapsed or Refractory Mantle Cell Lymphoma (MCL) and Diffuse Large B-Cell Lymphoma (DLBCL)

* 07-C-0058:
A Phase II Study of Sorafenib and Bevacizumab in Epithelial Ovarian, Fallopian, and Peritoneal Cancer

* 07-C-0006:
A Phase 1/2a Study Evaluating the Safety, Pharmacokinetics and Efficacy of ABT-263 in Subjects with Relapsed or Refractory Lymphoid Malignancies

* 06-NR-0229:
Neurotropin Treatment of Fibromyalgia

* 06-I-0086:
A Cohort Observational Study Evaluating Predictors, Incidence and Immunopathogenesis of Immune Reconstitution Syndrome (IRIS) in HIV-1 Infected Patients with CD4 Count Less Than or Equal to 100 Cells/microL Who Are Initiating Antiretroviral Therapy

* 06-HG-0134:
Natural History and Biology of Dermal Neurofibromas in Neurofibromatosis Type 1

* 06-HG-0055:
Functional Imaging in Subjects with Glucocerebrosidase Mutations

* 06-H-0222:
Role of Helicobacter Pylori and Its Toxins in Pulmonary and Oropharyngeal Disease

* 06-H-0217:
Genetic Disorders of Mucociliary Clearance

* 06-H-0156:
A Pilot Study of the Safety and Activity of Escalating Doses of AMD3100 to Mobilize CD34+ Cells in Healthy Volunteers

* 06-H-0082:
Telomere Repair Gene Mutations in Inflammatory Bowel Disease

* 06-H-0072:
Atorvastatin as a Disease Modifying Agent in Stage II and III Pulmonary Sarcoidosis: A Randomized, Double-Blind, Placebo-Controlled Trial

* 06-H-0034:
A Randomized Study of Three Immunosuppressive Regimens in Treatment Naive Patients with Severe Aplastic Anemia: Horse ATG/CsA Taper vs Rabbit-ATG/CsA vs Alemtuzumab

* 06-EI-0236:
National Ophthalmic Genotyping and Phenotyping Network, Stage 1 - Creation of DNA Repository for Inherited Ophthalmic Diseases

* 06-EI-0050:
Multicenter Uveitis Steroid Treatment (MUST) Trial Protocol

* 06-DK-0183:
Gene Expression and Release of Inflammatory Mediators in Overweight Subjects Before and After Weight Loss

* 06-DK-0025:
The Effects of Lithium Carbonate on Low Dose Radioiodine Ablation in Early Thyroid Cancer Treatment

* 06-D-0206:
Open-Label, Dose-Escalation Study Evaluating the Safety of a Single Administration of AdhAQP1, an Adenoviral Vector Encoding Human Aquaporin-1 to One Parotid Salivary Gland in Individuals with Irradiation-Induced Parotid Salivary Hypofunction

* 06-CH-0090:
Evaluation of Whether the Selective Progesterone Receptor Modulator CDB-2914 Can Shrink Leiomyomata

* 06-CH-0010:
Remodeling of Chromatin-Based Epigenetic Structures in Development and Aging

* 06-C-0233:
A Phase I/II Study of the RAF Kinase and Receptor Tyrosine Kinase Inhibitor Sorafenib (BAY 43-9006, NSC# 724772 IND# 69896) in Children with Refractory Solid Tumors or Refractory Leukemias

* 06-C-0227:
Phase I Trial of Intravenous Fenretinide (4-HPR) for Patients with Hematologic Malignancies

* 06-C-0198:
A Pilot Pediatric/Adult Study of Gene Expression Profiling and Clinical Characterization of Phototoxicity

* 06-C-0150:
A Phase II Clinical Trial of Anti-Tac(Fv)-PE38 (LMB-2) Immunotoxin for CD25 Positive Hairy Cell Leukemia

* 06-C-0112:
A Phase II Clinical Trial of the Histone Deacetylase Inhibitor Valproic Acid in Combination with Temodar and Radiation Therapy in Patients with High Grade Gliomas: Multi-Institutional Trial

* 06-C-0083:
Phase I and Pharmacokinetic Study of BAY 43-9006 (Sorafenib) in Patients with Kaposi's Sarcoma

* 06-C-0043:
Phase II Trial of Chemotherapy in Sporadic and Neurofibromatosis Type 1 Associated High Grade Malignant Peripheral Nerve Sheath Tumors

* 05-N-0245:
A Six Month Double-Blind, Placebo-Controlled Phase 2 Clinical Trial to Determine the Safety and Efficacy of Idebenone Administered to Patients with Friedreich's Ataxia

* 05-N-0228:
The Role of Cortical Coherence in Focal Hand Dystonia

* 05-N-0189:
Neuropathological Basis of Spasmodic Dysphonia and Related Voice Disorders

* 05-HG-0236:
Pilot Study of the Use of Intravenous Immune Globulin in Hereditary Inclusion Body Myopathy

* 05-HG-0152:
Variation in Gene Expression in Neurofibromatosis Type 1

* 05-HG-0076:
Long-Term Clinical Trial of Nitisinone in Alkaptonuria

* 05-HG-0004:
Clinical Investigations into Hutchison-Gilford Progeria Syndrome

* 05-H-0242:
A Pilot Study of Alemtuzumab (Campath) in Patients with Relapsed or Refractory Severe Aplastic Anemia

* 05-H-0206:
A Pilot Study of Alemtuzumab (Campath[R]) in Patients with Myelodysplastic Syndrome (MDS)

* 05-EI-0096:
Natural History and Genetic Studies of Usher Syndrome

* 05-DK-0119:
Peripheral Thyroid Hormone Conversion and Glucose and Energy Metabolism

* 05-DK-0015:
Retinoids for Podocyte Disease

* 05-CH-0037:
The Effects of Hydrocortisone, Melatonin, and Placebo on Symptoms of Jet Lag

* 05-CH-0013:
Adrenal Function in Critical Illness

* 05-CC-0216:
Prospective Assessment of Functional Status, Psychosocial Adjustment, Health Related Quality of Life and the Symptom Experience in Patients Treated with Allogeneic Hematopoietic Stem Cell Transplantation

* 05-CC-0093:
The Effect of Animal-Assisted Therapy on Distress in Oncology Patients Being Treated for Pain

* 05-CC-0041:
Endothelial Cell Dysfunction in Pulmonary Arterial Hypertension: Biomarkers, Mechanisms of Disease and Novel Therapeutic Targets

* 05-C-0252:
Phase III Randomized Study of R-CHOP v. Dose-Adjusted EPOCH-R with Molecular Profiling in Untreated de Novo Diffuse Large B-Cell Lymphomas

* 05-C-0241:
A Pilot Study of Image Guided Prostate and Pelvic Nodal Irradiation with Intensity Modulated Radiation Therapy (IMRT) in Prostate Cancer

* 05-C-0229:
A Randomized Pilot Phase II Study of Docetaxel Alone or in Combination with PANVAC(Trademark)-V (Vaccinia) and PANVAC(Trademark)-F (Fowlpox) in Adults with Metastatic Breast Cancer

* 05-C-0191:
A Phase I Study of Image Guided Dose Escalation with Intensity Modulated Radiation Therapy (IMRT) to Histologically Confirmed Regions of Prostate Cancer

* 05-C-0170:
Randomized Phase II Study of Dose-Adjusted EPOCH-Rituximab-Bortezomib (EPOCH-R-B) Induction Followed by Bortezomib Maintenance Versus Observation in Untreated Mantle Cell Lymphoma with Microarray Profiling and Proteomics

* 04-N-0056:
The Neural Immune Mechanisms and Genetic Influences on Chronic Pelvic Pain in Women with Endometriosis

* 04-M-0183:
Association between Adenosine Receptor Gene Polymorphisms and Physiological Responses to Caffeine in Subjects with Panic Disorder and Healthy Controls

* 04-H-0213:
Cytokine Gene Polymorphisms in Bone Marrow Failure

* 04-H-0179:
Peripheral Blood Hematopoietic Progenitor Cell Mobilization Using Granulocyte Colony Stimulating Factor (G-CSF) Combined with AMD3100 in Healthy Volunteers

* 04-H-0112:
Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation Followed by T Cell Add-Back for Hematological Malignancies - Effect of Peritransplant Cyclosporine on Chimerism

* 04-H-0078:
Peripheral Blood Hematopoietic Progenitor Cell Mobilization with AMD 3100 (Mozobil) in Healthy Volunteers Previously Mobilized with G-CSF

* 04-CC-0070:
Exploring Patient-Provider Trust among Individuals with End-Stage Renal Disease

* 04-CC-0046:
Citrate Effects and Bone Density Studies in Long-Term Apheresis Donors

* 04-C-0257:
A Phase II Trial of Docetaxel, Thalidomide, Prednisone and Bevacizumab in Patients with Androgen-Independent Prostate Cancer

* 04-C-0246:
An Open Label Pilot Study to Evaluate the Safety and Tolerability of PANVAC-V (Vaccinia) and PANVAC-F (Fowlpox) in Combination with Sargramostim in Adults with Metastatic Carcinoma

* 04-C-0238:
A Phase II Study of 17-Allylamino-17-Demethoxygeldanamycin in Patients with Von Hippel Lindau Disease and Renal Tumors

* 04-C-0232:
A Multi-Institutional Study of Proteomic Evaluation of Epithelial Ovarian Cancer, Primary Peritoneal Cancer, and Fallopian Tube Cancer Patients in First Clinical Remission: Development of a Protein Fingerprint Profile of Relapse

* 04-C-0177:
A Pilot Study of Tc-94m Sestamibi PET MDR Imaging

* 04-C-0171:
A Prospective Histopathologic Study of Dynamic Contrast Enhanced MRI for Prostate Cancer Delineation and Characterization with the APT-MRI System

* 04-C-0155:
Barrett's Esophagus Early Detection Study

* 04-C-0089:
Phase I Open-Label Single-Dose Study of Humanized Mik-Beta-1 Monoclonal Antibody Directed Toward the IL-2R/IL-15R-Beta Subunit (CD122) in T Cell Large Granular Lymphocytic Leukemia

* 04-C-0055:
Allogeneic HSCT without Preparative Chemotherapy or with Low-Intensity Preparative Chemotherapy using Sirolimus and Sirolimus-Generated Donor Th2 Cells for Therapy of Refractory Leukemia, Lymphoma, Myeloma, or Myelodysplastic Syndrome

* 03-N-0293:
Induction of Mucosal Tolerance to Human E-Selectin for the Secondary Prevention of Stroke

* 03-M-0143:
Randomized, Double-Blinded, Placebo Controlled Study of the Effects of Modafinil on Cognitive Function in Patients with Schizophrenia and Normal Controls Based on COMT Genotype

* 03-M-0035:
Screening, Evaluation, Diagnosis, Treatment Optimization and Follow-up for Childhood Onset Psychotic Disorders

* 03-HG-0313:
Genetic Analysis of Gray Platelet Syndrome

* 03-HG-0264:
Clinical and Molecular Investigations Into Ciliopathies

* 03-H-0282:
Characterization of Cardiac Function in Subjects with Hereditary Hemochromatosis Who Are New York Heart Association Functional Class I

* 03-H-0249:
A Randomized Trial of Immunosupression in Aplastic Anemia Patients with Refractory Pancytopenia or Suboptimal Hematologic Response after h-ATG/CsA Treatment

* 03-H-0201:
Cytokine Gene Polymorphisms in Allotransplant Donors

* 03-H-0193:
A Randomized Trial of a Novel Immunosuppressive Combination of ATG, CsA and Sirolimus (Rapamune) vs a Slow Taper Cyclosporine Regimen in Subjects with Severe Aplastic Anemia

* 03-H-0192:
Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation Followed by T Cell Add-Back for Hematological Malignancies Effect of Irradiated Donor Lymphocytes on Chimerism

* 03-H-0051:
Collection of Blood, Stool, Bone Marrow and/or Tissue Samples from Subjects with Hepatitis-Associated Aplastic Anemia

* 03-DK-0245:
Effect of AC 2993 (Synthetic Exendin-4) - Administered Alone or in Combination with Daclizumab - on Islet Function in Patients with Type I Diabetes

* 03-DK-0098:
Study of Thyrotropin Releasing Hormone in Patients with Thyroid or Pituitary Abnormalities

* 03-CC-0301:
Health Beliefs and Health Behavior Practices among Minorities with Rheumatic Diseases

* 03-CC-0128:
Development and Evaluation of Techniques for Computer Aided Detection and Diagnosis from Radiologic Images

* 03-C-0304:
Phase 2 Trial of Alemtuzumab and Dose-Adjusted Epoch in Chemotherapy Naive Aggressive T and NK-Cell Lymphomas

* 03-C-0190:
Trans-Rectal Placement of Prostatic Fiducial Markers under MR-Guidance in Patients Receiving External Beam Radiotherapy for Prostate Cancer: A Pilot Study

* 03-AR-0133:
Clinically Important Changes in Rheumatoid Arthritis

* 03-AR-0130:
Genetic Determinants of Ankylosing Spondylitis Severity - Cross Sectional Study

* 02-M-0239:
Randomized, Double-Blinded, Placebo Controlled Study of the Effects of Tolcapone and Entacapone on Cognitive Function in Patients with Schizophrenia and Normal Controls Based on COMT Genotype

* 02-M-0092:
Reward-Related Processes and Brain Function

* 02-M-0036:
A Behavioral and Functional Neuroimaging Study of Inhibitory Motor Control

* 02-I-0080:
The Gemini Study: Study of the Long-Term Safety and Persistence of Cells Following Cell Transfers or Gene Therapy in Identical Twins Discordant for HIV Infection

* 02-H-0265:
Identification of Genes Expressed in Atherosclerotic Plaques

* 02-H-0250:
A Phase I/II Study of HLA-matched Mobilized Peripheral Blood Hematopoietic Stem Cell Transplantation for Advanced Mycosis Fungoides/Sezary Syndrome Using Nonmyeloablative Conditioning with Campath-1H

* 02-DK-0022:
Long-Term Efficacy of Leptin Replacement in Treatment of Lipodystrophy

* 02-CH-0309:
The Diagnostic Performance of Screening Tests for the Diagnosis of Cushing's Syndrome

* 02-CH-0278:
Dyadic Interactions in Depressed and Non-Depressed Mothers and Their Infants

* 02-CC-0247:
Values at the Bedside: A Survey of European Physicians Regarding Ethical Dilemmas in Clinical Practice

* 02-C-0268:
Prospective Study of Prophylactic Salpingo-Oophorectomy and Longitudinal CA-125 Screening Among Women at Increased Genetic Risk of Ovarian Cancer

* 02-C-0215:
Amifostine as a Rectal Protector during External Beam Radiotherapy for Prostate Cancer: A Phase II Study

* 02-C-0212:
Clinical, Genetic, Behavioral, Laboratory and Epidemiologic Characterization of Individuals and Families at High Risk of Breast/Ovarian Cancer

* 02-C-0207:
A Phase II Study of MR-Guided High Dose Rate Brachytherapy Boosts For Prostate Cancer

* 02-C-0193:
A Phase II Study of Pegylated Interferon Alfa-2b (Peg-Intron (TM)) in Children with Diffuse Pontine Gliomas

* 02-AR-0272:
A Phase I, Open-Labeled, Dose-Ascending Clinical Trial of Immunotherapy of MRA, A Humanized Anti-IL 6 Receptor Monoclonal Antibody, In Patients with Systemic Lupus Erythematosus

* 02-AR-0156:
A Randomized, Double-Blind, Placebo-Controlled Trial of Infliximab in Patients with Dermatomyositis and Polymyositis

* 01-N-0145:
Screening and Natural History: Primary Lateral Sclerosis and Related Disorders

* 01-M-0152:
Adolescence, Puberty, Hormones, and Emotion Regulation: An fMRI Study

* 01-DK-0249:
Ingested Interferon-Alpha: Prolongation or Permanence of the "Honeymoon" Phase in Newly Diagnosed Diabetes Mellitus

* 01-DK-0246:
Combination of Lamivudine and Adefovir Dipivoxil for Treatment of Chronic Hepatitis B

* 01-DK-0036:
Solitary Islet Transplantation for Type 1 Diabetes Mellitus Using Steroid Sparing Immunosuppression

* 01-C-0049:
Phase II Trial of Depsipeptide in Patients with Cutaneous T-Cell Lymphoma and Relapsed Peripheral T-Cell Lymphoma

* 01-C-0027:
Natural History of Plexiform in Neurofibromatosis Type I

* 01-C-0009:
Breast Imaging Screening Studies in Women at High Genetic Risk of Breast Cancer: Annual Follow-up Study

* 01-C-0008:
Breast Imaging Studies in Women at High Genetic Risk of Breast Cancer: Menstrual Cycle Pilot Study

* 00-N-0140:
A Prospective Natural History Study of VHL Patients with CNS Hemangioblastomas

* 00-HG-0058:
Genetic Analysis of Attention Deficit Hyperactivity Disorder (ADHD)

* 00-H-0169:
A Phase II Study of Antithymocyte Globulin (ATG) and Cyclosporine to Treat the Cytopenia of Myelodysplastic Syndrome (MDS)

* 00-H-0032:
Treatment of Severe Aplastic Anemia with Combined Immunosuppression: Antithymocyte Globulin (ATG) and Cyclosporine A (CSA), and Mycophenolate Mofetil (MMF)

* 00-DK-0186:
The Hep C Antiviral Long-Term Tx Against Cirrhosis (HALT-C) Trial: A Randomized Controlled Trial to Evaluate the Safety & Efficacy of Long-Term Peginterferon Alpha2A for Tx of Chronic Hep C in Patients Who Failed to Respond to Previous Interferon Therap

* 00-DC-0073:
Identification of Hereditary Auditory Temporal Processing Deficits

* 00-CH-0136:
A Trial of Pamidronate in Children with Osteogenesis Imperfecta

* 00-CC-0165:
Filgrastim-Mobilized Peripheral Blood Stem Cells for Allogeneic Transplantation Using Unrelated Donors Participating in the National Marrow Donor Program (NMDP)

* 00-C-0133:
Pilot Study of Idiotype Vaccine and EPOCH-Rituximab Chemotherapy in Untreated Mantle Cell Lymphoma

* 00-C-0018:
A Pilot Study of Proteomic Evaluation of Epithelial Ovarian Cancer Patients in First Clinical Remission: Development of a Protein Fingerprint Profile Associated with Relapse

* 99-HG-0056:
Pulmonary Fibrosis Associated with Rheumatoid Arthritis: Definition of the Natural History of Disease

* 99-H-0064:
Exploratory Study of Non-Myeloablative Allogeneic Stem Cell Transplantation and Donor Lymphocyte Infusions for Metastatic Neoplasms Refractory to Standard Therapy

* 99-H-0046:
Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation Followed by T-Cell Add-Back for Hematological Malignancies - Role of Cyclosporine

* 99-D-0070:
Natural History of Salivary Gland Dysfunction and Sjogren's Syndrome

* 99-C-0088:
(1)H-Nuclear Magnetic Resonance Spectroscopic Imaging of the Brain in Patients who Receive Neurotoxic Therapy

* 99-C-0081:
Methods in Education for Breast Cancer Genetics

* 99-C-0053:
Von Hippel-Lindau (VHL) Disease Genetic Epidemiology Study

* 97-M-0126:
Childhood Onset Psychotic Disorders: Characterization and Treatment with Atypical Neuroleptics

* 97-HG-0192:
Genetic Studies in the Amish and Mennonites

* 97-HG-0085:
Therapeutic Clinical Trial of Oral Pirfenidone for the Pulmonary Fibrosis of Hermansky-Pudlak Syndrome

* 97-H-0196:
A Phase II Study of HLA-Matched Peripheral Blood Stem Cell Transplantation for Metastatic Renal Cell Carcinoma as Adoptive Allogeneic Immunotherapy

* 97-H-0130:
Collection of Blood and Bone Marrow from Healthy Volunteers and Patients for Research Purposes

* 97-H-0117:
A Randomized Trial of Antithymocyte Globulin and Cyclosporine versus Cyclophosphamide and Cyclosporine in the Treatment of Severe Aplastic Anemia

* 97-H-0099:
HLA-Matched Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation Followed by T Cell Add-Back for Hematological Malignancies

* 97-C-0178:
Treatment of Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL): DNA Microarray Gene Expression Analysis

* 97-C-0093:
A Pilot Study of 1H-Nuclear Magnetic Resonance Spectroscopic Imaging in Pediatric Patients with Primary and Metastatic Brain Tumors

* 97-C-0040:
EPOCH Chemotherapy Plus Rituximab for Previously Treated Patients with AIDS-Associated Lymphoma

* 96-CH-0101:
Population Differences in the Insulin Sensitivity, Resting Energy Expenditure, and Body Composition of Overweight Children and Children of Overweight Parents

* 96-CH-0033:
An Open, Randomized, Long-Term Clinical Trial of Flutamide, Testolactone, and Reduced Hydrocortisone Dose vs. Conventional Treatment of Children with Congenital Adrenal Hyperplasia

* 95-HG-0165:
Outcomes of Education and Counseling for HNPCC / Lynch Syndrome Testing

* 95-HG-0158:
Genetic Analysis of Hereditary Prostate Cancer

* 95-H-0167:
Effect of Hypoxia and Smoking on Oxidation of Proteins and Nucleic Acids in Human Volunteers

* 92-CH-0034:
Studies of Growth Deficiency and Growth Hormone Treatment in Children with Osteogenesis Imperfecta Types III and IV

* 92-CC-0141:
The Cardiopulmonary Effects of Endotoxin in Normal Human Volunteers

* 91-M-0230:
Mechanisms of Individual Variation of Dextroamphetamine Effects in Normal Human Subjects

* 91-M-0124:
Structural and Functional Imaging of Neuropsychiatric Patients and Normal Volunteers with 1.5 Tesla MRI

* 90-DK-0137:
Evaluation of the Gastrinoma in Patients with Zollinger-Ellison Syndrome

* 90-CH-0149:
Early Copper Histidine Therapy in Menkes Disease

* 88-I-0172:
A Phase III Study with Long-Term Follow-Up of Zidovudine Versus Zidovudine and Alpha-Interferon Versus Alpha-Interferon in Patients with Early HIV Infection

* 88-CH-0032:
Specificity of Mother-Infant Interaction: The Influence of Maternal Age, Employment Status, and Parenthood Status

* 86-H-0088:
Lymphocytapheresis of Patients with Pancytopenia

* 85-M-0115:
Biological Markers in Childhood Psychiatric Disorders

* 85-H-0105:
Cardiovascular Evaluation of Homozygous Familial Hypercholesterolemia

* 79-C-0111:
The Treatment of Stage I and II Carcinoma of the Breast with Mastectomy and Axillary Dissection vs. Excisional Biopsy, Axillary Dissection, and Definitive Irradiation

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