National Heart, Lung and Blood Institute (NHLBI)s

National Heart, Lung and Blood Institute (NHLBI)

137 Protocols (70 Active Accrual of new subjects, 67 Follow-up of previously enrolled subjects)

 17-H-0069:

Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease

 17-H-0056:

Pathophysiology of Acute Pain in Patients with Sickle Cell Disease

 17-H-0019:

A Randomized Trial of Sirolimus (Rapamune(R)) for Relapse Prevention in Patients with Severe Aplastic Anemia Responsive to Immunosuppressive Therapy

 16-H-0132:

CADASIL Disease Discovery

 16-H-0063:

Williams Syndrome Skin and Vascular Elasticity Study (WS-SAVE Study)

 16-H-0019:

High Image Matrix CT Reconstruction

 15-H-0172:

A Pilot Phase II Study Using Ibrutinib and Short-Course Fludarabine in Previously Untreated Patients with Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)

 15-H-0155:

Hereditary Parkinson Disease Natural History Protocol

 15-H-0024:

Genes Involved in Lipid Disorders

 15-H-0016:

A Phase II Study Using ACP-196 in Patients with Relapsed/Refractory and Treatment Naive Deletion 17p CLL/SLL: Pharmacodynamic Assessment of BTK Inhibition and Anti-Tumor Response.

 14-HG-0048:

Genomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African-Americans Study (GENE-FORECAST)

 14-H-0077:

Nonmyeloablative Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease and Beta-Thalassemia in Individuals with Higher Risk of Transplant Failure

 13-H-0194:

Inflammatory Characterization of Known or Possible Cardiovascular Diseases

 13-H-0065:

Human Translational Studies of Inflammation and Cardiometabolic Diseases: The Psoriasis, Atherosclerosis and Cardiometabolic Disease (PACI) Initiative

 13-H-0060:

Analysis of Samples Collected from a Subject who Received ACP- 501 (Human Recombinant Lecithin:Cholesterol Acyltransferase [rhLCAT])

 12-H-0150:

Eltrombopag Added to Standard Immunosuppression in Treatment-Naive Severe Aplastic Anemia

 12-H-0092:

An Intravenous, Open-Label, Single-Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of rhLCAT in Patients with Stable Coronary Artery Disease

 12-H-0035:

A Phase II study of Ibrutinib for Patients with Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL) Who Need Therapy and are Older than 65 or have a 17p Deletion

 11-H-0209:

Male Hormones for Telomere Related Diseases

 11-H-0134:

A Pilot Study of a Thrombopoietin-Receptor Agonist (TPO-R Agonist), Eltrombopag, in Moderate Aplastic Anemia Patients

 11-H-0046:

Cross-Sectional Characterization of Idiopathic Bronchiectasis

 10-H-0083:

A Phase I Trial of Safety and Immunogenicity of Gardasil Vaccination Post Stem Cell Transplantation in Patients with and without Immunosuppression

 09-H-0239:

Cellular and Molecular Characterization of the Immune Response in Healthy NIH Employees at Baseline, and After Immunization with the H1N1 or Seasonal Influenza Vaccines

 09-H-0225:

Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Severe Congenital Anemias Including Sickle Cell Disease and Beta-Thalassemia

 08-H-0186:

Safety and the Anti- Tumor Effects of Escalating Doses of Adoptively Infused Ex Vivo Expanded Autologous Natural Killer (NK) Cells Against Metastatic Cancers or Hematological Malignancies Sensitized to NK-TRAIL Cytotoxicity with Bortezomib

 08-H-0046:

Co-Infusion of Umbilical Cord Blood and Haploidentical CD34+ Cells Following Nonmyeloablative Conditioning as Treatment for Severe Aplastic Anemia and MDS Associated with Severe Neutropenia Refractory to Immunosuppressive Therapy

 07-H-0005:

Pilot Study of Topical Dexamethasone 0.01% Solution for Prevention of Oral Chronic Graft Versus Host Disease

 06-H-0217:

Genetic Disorders of Mucociliary Clearance

 06-H-0190:

Treatment of T-Large Granular Lymphocyte (T-LGL) Lymphoproliferative Disorders with Alemtuzumab (Campath)

 06-H-0072:

Atorvastatin as a Disease Modifying Agent in Stage II and III Pulmonary Sarcoidosis: A Randomized, Double-Blind, Placebo-Controlled Trial

 03-H-0170:

Nonmyeloablative Allogeneic Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Severe Congenital Anemias Including Sickle Cell Disease (SCD) and B-Thalassemia

 01-H-0122:

Collection and Storage of Umbilical Cord Hematopoietic Stem Cells for Sickle Cell Disease Therapy

 01-H-0088:

Determining the Prevalence and Prognosis of Secondary Pulmonary Hypertension in Adult Patients with Sickle Cell Anemia

 99-H-0076:

Asthma Sample Collection Protocol

 99-H-0050:

Non-Myeloablative Allogeneic Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Hematologic Malignancies in High Risk Patients and in Patients with Debilitating Hematologic Diseases

 85-H-0105:

Cardiovascular Evaluation of Homozygous Familial Hypercholesterolemia

 79-H-0100:

Teaching Protocol for the Evaluation of Plasma Lipoproteins

 76-H-0051:

Lipoprotein Metabolism in Normal Volunteers and Hyperlipoproteinemic Patients

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