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43 Studies found from all possible combinations of your search terms. Select a protocol that you wish to review.
Protocol Number Title Protocol Status Min-Max Age Institute Keywords
001651-DKA Pilot Study to Assess Feasibility of Adipose Tissue Triglyceride (TG) Labelling in Familial Partial Lipodystrophy (FPLD)Participants currently recruited/enrolled18-65 YearsNIDDKLipodystrophy Familial Partial
000665-DKA Randomized Double-Blind Placebo-Controlled Study of the LEPR Agonist Antibody REGN4461 for the Treatment of Metabolic Abnormalities in Patients with Familial Partial LipodystrophyCompleted Study; data analyses ongoing18-90 YearsNIDDKLipodystrophy Familial Partial
000756-DKPhase II Study of Growth Hormone Inhibition Using Pegvisomant In Severe Insulin ResistanceParticipants currently recruited/enrolled18-65 YearsNIDDKLipodystrophy Partial
15-DK-0002Compassionate Use of Metreleptin in Previously-Treated Patients with Partial LipodystrophyNo longer recruiting/follow-up only0-98 YearsNIDDKLipodystrophy Partial
14-C-0037A Phase 2 Study of the MET Kinase Inhibitor INC280 in Papillary Renal Cell CancerCompleted Study; data analyses ongoing18-125 YearsNCI Familial Partial
001542-CPhase Ib Study of Imatinib to Increase RUNX1 Activity in Participants with Germline RUNX1 DeficiencyParticipants currently recruited/enrolled18-120 YearsNCI Familial
000757-DKNatural History of Pregnancy and Pregnancy Outcomes in Metreleptin-Treated vs Untreated Subjects with LipodystrophyParticipants currently recruited/enrolled0-98 YearsNIDDKLipodystrophy
20-N-0077Study of Volition: Behavioral analysis and Clinical Neurophysiological AnalysisCompleted Study; data analyses ongoing25-45 YearsNINDSPartial
20-DK-0168LYNC-LD Prospective Multicenter Natural History Study of Lipodystrophy Syndromes to Determine Prevalence, Incidence and Predictors of Diabetes and Severe Hypertriglyceridemia, and their Complications.Participants currently recruited/enrolled3-120 YearsNIDDKLipodystrophy
20-DK-0079A Randomized, Double-Blinded, Placebo-Controlled Study of REGN4661, A Leptin Receptor Agonist Antibody, In Patients with Generalized LipodystrophyCompleted Study; data analyses ongoing12-90 YearsNIDDKLipodystrophy
20-CH-0165Androgen Receptor, Implications for Health and Wellbeing: Natural History Study of Individuals with Androgen InsensitivityParticipants currently recruited/enrolled1-99 YearsNICHDPartial
20-C-0106Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients with BAP1 Tumor Predisposition SyndromeParticipants currently recruited/enrolled30-125 YearsNCI Familial
19-I-0080Haploidentical Transplant for Patients with Chronic Granulomatous Disease (CGD) using Alemtuzumab, Busulfan and TBI with Post-Transplant CyclophosphamideParticipants currently recruited/enrolled4-65 YearsNIAIDPartial
19-HG-0059Longitudinal Studies of Patients and Families with Familial Platelet Disorders with Associated Myeloid Malignancy (FPDMM) Caused by RUNX1 Germline Variants or FPDMM-Like ConditionsParticipants currently recruited/enrolled0-125 YearsNHGRIFamilial
19-C-0016Natural History and Biospecimen Acquisition Study for Children and Adults with Rare Solid TumorsParticipants currently recruited/enrolled0-125 YearsNCI Familial
18-N-0066Investigating Epilepsy: Screening and EvaluationParticipants currently recruited/enrolled8-125 YearsNINDSPartial
17-C-0087Lu-177-DOTATATE (Lutathera) in Therapy of Inoperable Pheochromocytoma/ ParagangliomaParticipants currently recruited/enrolled18-125 YearsNCI Familial
17-C-0043Hereditary Gastric Cancer Syndromes: An Integrated Genomic and Clinicopathologic Study of the Predisposition to Gastric CancerParticipants currently recruited/enrolled2-125 YearsNCI Familial
16-DK-0173MEASuRE: Metreleptin Effectiveness and Safety RegistryParticipants currently recruited/enrolled0-98 YearsNIDDKLipodystrophy
16-C-0066Phase I Study of MK-3475 (Pembrolizumab) in Patients with Human Immunodeficiency Virus (HIV) and Relapsed/Refractory or Disseminated Malignant NeoplasmCompleted Study; data analyses ongoing18-120 YearsNCI Partial
15-DK-0003Compassionate Use of Metreleptin in Previously-Treated Patients with Generalized LipodystrophyParticipants currently recruited/enrolled0-98 YearsNIDDKLipodystrophy
14-C-0001Phase II Study of Axitinib (AG-013736) with Evaluation of the VEGF-pathway in Metastatic, Recurrent or Primary Unresectable Pheochromocytoma/ParagangliomaCompleted Study; data analyses ongoing18-125 YearsNCI Partial
13-H-0060Analysis of Samples Collected from a Subject who Received ACP- 501 (Human Recombinant Lecithin:Cholesterol Acyltransferase [rhLCAT])Completed Study; data analyses ongoing18-100 YearsNHLBIFamilial
11-N-0051Surgery as a Treatment for Medically Intractable EpilepsyParticipants currently recruited/enrolled8-99 YearsNINDSPartial
10-DK-0102Clinical and Genetic Studies in Familial Non-Medullary Thyroid CancerParticipants currently recruited/enrolled7-90 YearsNIDDKFamilial
09-I-0126Pathogenesis and Genetic Basis of Physical Induced Urticarial SyndromesNo longer recruiting/follow-up only2-90 YearsNIAIDFamilial
08-H-0046Co-Infusion of Umbilical Cord Blood and Haploidentical CD34+ Cells Following Nonmyeloablative Conditioning as Treatment for Severe Aplastic Anemia and MDS Associated with Severe Neutropenia Refractory to Immunosuppressive TherapyCompleted Study; data analyses ongoing4-75 YearsNHLBIPartial
08-DK-0098Natural History of Familial Carcinoid TumorParticipants currently recruited/enrolled18-125 YearsNIDDKFamilial
08-C-0130A Phase II Trial of Peginterferon alfa-2b (PEG-Intron) for Neurofibromatosis Type 1 Related Unresectable, Symptomatic or Life-Threatening Plexiform NeurofibromasCompleted Study; data analyses ongoing0-21 YearsNCI Partial
06-CH-0011Natural History Study of Patients with Excess AndrogenParticipants currently recruited/enrolled0-99 YearsNICHDFamilial
04-I-0286A Longitudinal Study of Familial Hypereosinophilia (FE): Natural History and Markers of Disease ProgressionParticipants currently recruited/enrolled1-100 YearsNIAIDFamilial
03-AR-0173Studies of Natural History, Pathogenesis, and Outcomes in Autoimmune and Inflammatory Diseases Including Juvenile DermatomyositisParticipants currently recruited/enrolled2-125 YearsNIAMSLipodystrophy
02-C-0212Clinical, Genetic, Behavioral, Laboratory and Epidemiologic Characterization of Individuals and Families at High Risk of Breast/Ovarian CancerCompleted Study; data analyses ongoing18-100 YearsNCI Familial
02-C-0178Multidisciplinary Etiologic Study of Familial Testicular CancerNo longer recruiting/follow-up only12-125 YearsNCI Familial
02-C-0052Etiologic Investigation of Cancer Susceptibility in Inherited Bone Marrow Failure Syndromes: A Natural History StudyParticipants currently recruited/enrolled0-125 YearsNCI Familial
01-N-0206Phenotype/Genotype Correlations in Movement DisordersParticipants currently recruited/enrolled2-100 YearsNINDSFamilial
01-M-0232Positron Emission Tomography (PET) Scanning in Dopamine Disorders: Parkinson's Disease and SchizophreniaParticipants currently recruited/enrolled18-90 YearsNIMH Familial
01-D-0184A Natural History Study of Bone and Mineral DisordersParticipants currently recruited/enrolled0-125 YearsNIDCRFamilial
00-H-0051Cutaneous Tumorigenesis in Patients with Tuberous SclerosisParticipants currently recruited/enrolled18-90 YearsNHLBIFamilial
94-HG-0105An Exploratory Study of the Genetics, Pathophysiology, and Natural History of Autoinflammatory DiseasesParticipants currently recruited/enrolled0-115 YearsNHGRIFamilial
89-C-0086Von Hippel-Lindau (VHL): Clinical Manifestations, Diagnosis, Management and Molecular Bases of Inherited Renal and Other Urologic Malignant DisordersParticipants currently recruited/enrolled2-125 YearsNCI Familial
85-H-0105Cardiovascular Evaluation of Homozygous Familial HypercholesterolemiaCompleted Study; data analyses ongoing2-70 YearsNHLBIFamilial
78-C-0039Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of CancerNo longer recruiting/follow-up only0-125 YearsNCI Familial