This study is currently recruiting participants.
Number
00-C-0078
Sponsoring Institute
National Cancer Institute (NCI)
Recruitment Detail
Type: Participants currently recruited/enrolled Gender: Male & Female Min Age: 18 Years Max Age: N/A
Referral Letter Required
Yes
Population Exclusion(s)
Children;Fetuses;Neonates;Pregnant Women
Keywords
Assays; Resistance; Biopsy Samples; Specimen Acquisition; Cancer Cells; Natural History
Recruitment Keyword(s)
None
Condition(s)
Renal Cell Carcinoma; Lung carcinoma; Cervical Carcinoma
Investigational Drug(s)
Investigational Device(s)
Intervention(s)
Supporting Site
National Cancer Institute
Patients with cancer who are 18 years or older may be eligible for this study. Participants will have 40 milliliters (3 tablespoons) of blood drawn at the beginning of the study; additional samples will be obtained periodically during the course of treatment. A small sample of tumor or normal tissue will be taken from patients who undergo surgery or tumor biopsy (removal of a small piece of tumor) for medical reasons or as part of a research treatment protocol. Patients who do not require surgery or biopsy may be asked permission to obtain a tumor sample. Depending on the location of the tumor, this may be done by: 1) withdrawing bone marrow through a small needle; 2) removing fluid from the chest or abdomen; 3) removing a small tumor sample through a needle; or 4) removing the sample with a small incision into or around the tumor. These procedures will be done only if they are of low risk to the patient.
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INCLUSION CRITERIA: 1. Participants 18 years of age and older are eligible. 2. Participants must have a performance status of ECOG 0, 1, 2, or 3 for admission to this protocol. 3. Participants with malignancy are eligible. 4. Participants requiring a surgical procedure for any medical indication can be included on study. 5. Participants requiring biopsy or any procedure for any medical indication can be included on study. 6. Participants not requiring biopsy for a medical indication can be included on the study solely for the purpose of obtaining research samples, including blood, pleural fluid, or peritoneal fluid, or biopsy samples. No radiology tests will be used in the procedure to collect a sample that would not be otherwise used for an appropriate medical indication. 7. Normal volunteers 18 years of age and older are eligible to enroll. Normal volunteers must be willing to sign informed consent and must be willing to provide samples to be used for research. EXCLUSION CRITERIA: 1. Pregnant individuals will not be eligible due to potential risks to the fetus associated with radiologic procedures required for biopsy. 2. Children will not be eligible because of potential risks from complications due to procedures involved in obtaining the biopsies. 3. Normal volunteers with a history of a clotting disorder may not enroll.
1. Participants 18 years of age and older are eligible.
2. Participants must have a performance status of ECOG 0, 1, 2, or 3 for admission to this protocol.
3. Participants with malignancy are eligible.
4. Participants requiring a surgical procedure for any medical indication can be included on study.
5. Participants requiring biopsy or any procedure for any medical indication can be included on study.
6. Participants not requiring biopsy for a medical indication can be included on the study solely for the purpose of obtaining research samples, including blood, pleural fluid, or peritoneal fluid, or biopsy samples. No radiology tests will be used in the procedure to collect a sample that would not be otherwise used for an appropriate medical indication.
7. Normal volunteers 18 years of age and older are eligible to enroll. Normal volunteers must be willing to sign informed consent and must be willing to provide samples to be used for research.
EXCLUSION CRITERIA:
1. Pregnant individuals will not be eligible due to potential risks to the fetus associated with radiologic procedures required for biopsy.
2. Children will not be eligible because of potential risks from complications due to procedures involved in obtaining the biopsies.
3. Normal volunteers with a history of a clotting disorder may not enroll.
Principal Investigator
Referral Contact
For more information: