This study is currently recruiting participants.
Number
14-AA-0066
Sponsoring Institute
National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Recruitment Detail
Type: Participants currently recruited/enrolled Gender: Male & Female Min Age: 18 Years Max Age: 65 Years
Referral Letter Required
No
Population Exclusion(s)
Children;Pregnant Women
Keywords
fMRI; Alcoholism; Phenotype; Imaging; EEG; Psychophysiology; Near Infrared
Recruitment Keyword(s)
None
Condition(s)
Alcohol Dependence; Alcohol Drinking; Alcoholism; Alcohol Use Disorder; Addiction
Investigational Drug(s)
Investigational Device(s)
Intervention(s)
Device: 7T MRI
Supporting Site
National Institute on Alcohol Abuse and Alcoholism
- Scientists know that alcohol use disorders affect brain structure. They want to know more about the effects of alcohol use disorders on a person s behavior. They want to develop tasks that can be done inside a scanner that can help them better understand these effects in later studies.
Objective:
- To develop tasks that investigate a person s behavior that can be used in later studies.
Eligibility:
- Inpatient participants of another study. They must be physically healthy right-handed adults 18-60 years old.
- Healthy right-handed volunteers 18-65 years old.
Design:
- Participants will be screened with medical history and physical exam. They will have an EKG to record heart activity. They will give blood and urine samples and have a psychiatric interview.
- Participants will have between one and three visits.
- Participants will be asked about their alcohol drinking to see if they have an alcohol use disorder.
- Participants will complete one of three simple computerized tasks either inside the magnetic resonance imagining (MRI) scanner or outside of it.
- The MRI scanner takes pictures of the brain. The scanner is a metal cylinder. Participants lie on a table that can slide in and out of the cylinder. They will be in the scanner for about 60 minutes. They may have to lie still for up to 20 minutes. The scanner makes loud knocking noises, but they will get earplugs.
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INCLUSION CRITERIA: -between 18-65 years of age. EXCLUSION CRITERIA: -Are not cleared on a neuromotor examination -Are currently receiving psychotropic medication -Inpatients only: Currently experiencing symptoms of withdrawal from alcohol (As determined by the most recent measurement within the past 30 days CIWA score > 8). -MRI Exclusion Criteria: --Presence of ferromagnetic objects in the body including implanted pacemakers, medication pumps, aneurysm clips, metallic prostheses (including metal pins and rods, heart valves or cochlear implants), shrapnel fragments, permanent eye liner or small metallic fragments in the eye that welders and other metal workers may have; --Are pregnant, as determined by a positive pregnancy test --Left handed --Claustrophobia.
-between 18-65 years of age.
EXCLUSION CRITERIA:
-Are not cleared on a neuromotor examination
-Are currently receiving psychotropic medication
-Inpatients only: Currently experiencing symptoms of withdrawal from alcohol (As determined by the most recent measurement within the
past 30 days CIWA score > 8).
-MRI Exclusion Criteria:
--Presence of ferromagnetic objects in the body including implanted pacemakers, medication pumps, aneurysm clips, metallic prostheses (including metal pins and rods, heart valves or cochlear implants), shrapnel fragments, permanent eye liner or small metallic fragments in the eye that welders and other metal workers may have;
--Are pregnant, as determined by a positive pregnancy test
--Left handed
--Claustrophobia.
Principal Investigator
Referral Contact
For more information: