National Eye Institute (NEI)s

National Eye Institute (NEI)

38 Protocols (20 Active Accrual of new subjects, 18 Follow-up of previously enrolled subjects)

 001647-EI:

National Ophthalmic Genotyping and Phenotyping Network, Stage 3 - Expansion of DNA and Data Repositories for Rare Inherited Ophthalmic Diseases

 000187-EI:

Adaptive Optics Imaging of Outer Retinal Diseases

 000108-EI:

An Observational Prospective Natural History Study of Stargardt-like Macular Dystrophy (STDG3) Secondary to Mutations in ELOVL4

 20-EI-0163:

Oral Metformin for Treatment of ABCA4 Retinopathy

 20-EI-0052:

A Phase I/IIa Trial for Autologous Transplantation of Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium for Geographic Atrophy Associated with Age-Related Macular Degeneration

 20-EI-0026:

An Observational Cross-Sectional Study of Virtual Reality Mobility Assessment of Functional Vision in Retinal Disease

 18-EI-0046:

Perception, Sensation, Cognition and Action in Humans

 17-EI-0112:

A Long-term Follow-up Study of Participants Enrolled in 11-EI-0147: Longitudinal Investigation of Dark Adaptation in Participants with Age-Related Macular Degeneration (DA_AMD)

 16-EI-0134:

Studies of the Natural History, Pathogenesis and Outcome of Ocular Disorders

 16-EI-0104:

Clinical and Molecular Studies in Families with Inherited Eye Disease

 16-EI-0090:

Natural History of Spinocerebellar Ataxia Type 7 (SCA7)

 16-EI-0024:

Rod and Cone Mediated Function in Retinal Disease

 15-EI-0128:

The Genetics of Inherited Eye Disease

 15-EI-0020:

Adaptive Optics Retinal Imaging

 14-EI-0064:

Whole Exome and Whole Genome Sequencing for Genotyping of Inherited and Congenital Eye Conditions

 13-EI-0049:

Pathogenesis and Genetics of Microphthalmia, Anophthalmia and Uveal Coloboma ( MAC)

 12-EI-0042:

NEI Intramural Biorepository for Retinal Diseases

 11-EI-0245:

Generation of Induced Pluripotent Stem (iPS) Cell Lines from Somatic Cells of Participants with Eye Diseases and from Somatic Cells of Matched Controls

 10-EI-0140:

Genotype - phenotype Study of Patients with Plaquenil-induced Retinal Toxicity

 08-EI-0102:

Screening Protocol for the Evaluation and Diagnosis of Potential Research Participants

 19-EI-0056:

A Survey Study of Retinitis Pigmentosa (RP) Clinical Measures and Repeatability Testing of Potential Outcome Measures.

 18-EI-0068:

An Investigation of Vitamin A Palmitate Supplementation in Patients with Reticular Pseudodrusen (RPD) and Delayed Dark Adaptation

 18-EI-0067:

An Investigation of Vitamin A Palmitate Supplementation in Patients with Age-Related Macular Degeneration (and without reticular pseudodrusen) and Delayed Dark Adaptation

 17-EI-0071:

AMD Ryan Initiative Study

 17-EI-0008:

The Natural History of Geographic Atrophy Associated with Age-Related Macular Degeneration

 16-EI-0169:

A Pilot Study to Investigate Ustekinumab (STELARA) for the Treatment of Active Sight-Threatening Uveitis

 16-EI-0046:

Uveitis/Intraocular Inflammatory Disease Biobank (iBank)

 15-EI-0202:

Evaluation of Oral Minocycline in the Treatment of Geographic Atrophy Associated with Age-Related Macular Degeneration

 15-EI-0038:

A Phase I/IIa Study of RS1 Ocular Gene Transfer for X-linked Retinoschisis

 14-EI-0171:

The Focal Electro-Oculogram in Macular Disease

 13-EI-0072:

Microbiome and Ocular Inflammatory Disease

 12-EI-0203:

Natural History of ABCA4-Related Retinopathies

 11-EI-0264:

A Pilot Study for the Evaluation of Minocycline as a Microglia Inhibitor in the Treatment of Central Retinal Vein Occlusions

 11-EI-0263:

A Pilot Study for the Evaluation of Minocycline as a Microglia Inhibitor in the Treatment of Branch Retinal Vein Occlusions

 11-EI-0147:

Longitudinal Investigation of Dark Adaptation in Participants with Age-Related Macular Degeneration

 08-EI-0043:

Age-Related Eye Disease Study (AREDS) and AREDS2 Follow-Up

 06-EI-0236:

National Ophthalmic Genotyping and Phenotyping Network Stage 1 - Creation of DNA Repository for Inherited Ophthalmic Diseases

 03-EI-0033:

X-Linked Juvenile Retinoschisis - Clinical and Molecular Studies