National Institutes of Health Clinical Center (CC)s

National Institutes of Health Clinical Center (CC)

69 Protocols (33 Active Accrual of new subjects, 36 Follow-up of previously enrolled subjects)

 001180-CC:

A Phase I/II Trial Evaluating Long-Term Use of a Pediatric Robotic Exoskeleton (P.REX/Agilik) to Improve Gait in Children with Movement Disorders

 000871-CC:

Mediterranean-like Unprocessed (CLEAN-MED) Diet Intervention Study of the Gut Microbiome of Healthy Adults

 000867-CC:

Humanitarian Use Device (HUD) Protocol for Use of Miltenyi CliniMACS (Registered Trademark) CD34 Reagent System in AML

 000767-CC:

Phase I Open Label Clinical Trial Using Resiniferatoxin, A Non-Opioid Medication, For the Management of Refractory Morton's Neuroma Pain

 000518-CC:

Observational Study of Dietary Intake and Dietary Behaviors in Adults with Sickle Cell Disease

 000417-CC:

Characterization of the Nociception Phenotype in Individuals with Intellectual Disability

 000411-CC:

A Feasibility Pilot Study of a Virtual Education-Based Transition Intervention to Improve Transition Readiness in Adolescent and Young Adults with Congenital Adrenal Hyperplasia.

 000268-CC:

NIH Intramural Research Program's Pregnancy Registry Protocol for Subjects and Their Partners

 000102-CC:

COVID-19, Chronic Adaptation and Response to Exercise (COVID-CARE): A Randomized Controlled Trial

 20-CC-0039:

A Feasibility Study to Evaluate the Combination of Electromagnetic Tracking and Optical Imaging with Indocyanine Green (ICG) for Hepatic Biopsies

 20-CC-0036:

Exploring a Dietary Behavior Intervention in African-Americans at Risk for Cardiovascular Disease: A Community Acceptability and Feasibility Study

 19-CC-0005:

Short or Long Infusion Duration for Platelets: The SOLID Platelet Study

 18-CC-0052:

Near-infrared Spectroscopy and Electroencephalography to Assess Cortical Activation During Motor Tasks in Infants and Toddlers with or at high-risk for Cerebral Palsy and Autism Spectrum Disorder Compared to Infants and Toddlers with Typical Development

 18-CC-0013:

A Randomized, Double-Blind, Placebo-Controlled Study of a Single Dose of Pembrolizumab in HIV-Infected Patients

 17-CC-0148:

Obtaining Samples from Human Subjects to Facilitate Basic, Translational and Clinical Research

 16-CC-0149:

Dopamine and Motor Learning in Cerebral Palsy

 15-CC-0091:

Pulmonary Effects of Bronchial Segmental Endotoxin Instillation in Humans

 13-CC-0210:

Evaluating an Extension Assist Knee Ankle Foot Orthosis to Improve Gait in Children with Movement Disorders

 13-CC-0180:

Studies of the Human Microbiome in Clinical Center Patients

 13-CC-0110:

Near-infrared Spectroscopy and Electroencephalography to Assess and Train Cortical Activation During Motor Tasks

 13-CC-0099:

Vasti Control of Patellofemoral Kinematics in Patients with Chronic Patellofemoral Pain.

 13-CC-0012:

A Natural History Study of Novel Biomarkers in Pulmonary Arterial Hypertension

 12-CC-0211:

A Pilot Study of the Effect of Spironolactone Therapy on Exercise Capacity and Endothelial Dysfunction in Pulmonary Arterial Hypertension

 12-CC-0139:

Estimation of Brain Biomechanics using MRI

 12-CC-0096:

Collection of Granulocytes by Apheresis of Healthy Donors Stimulated with Filgrastim (G-CSF) and Dexamethasone

 10-CC-0118:

Long Term Clinical Correlates of TBI: Imaging, Biomarkers, and Clinical Phenotyping Parameters

 10-CC-0115:

Imaging Techniques in MRI

 05-CC-0091:

Electromagnetic Tracking of Devices During Interventional Procedures

 04-CC-0119:

Biomarkers and Protein Mass Expression Profiles in Bronchoalveolar Lavage from Patients with Lung Infiltrates

 03-CC-0060:

Virtual Function Anatomy (VFA)

 99-CC-0168:

Collection and Distribution of Blood Components from Healthy Donors for In Vitro Research Use

 98-CC-0019:

Volunteer Scanning on MR

 90-CC-0168:

A Rigid Body Database on Human Movement

 001636-CC:

A Pilot Study of a Nature-Based Virtual Reality (VR) Intervention in Family Caregivers of Allogeneic Hematopoietic Stem Cell Transplant (HSCT) Recipients

 000736-CC:

Imaging Characterization of the Biomechanical Coupling of Brain and Skull: An Observational Study

 000123-CC:

Evaluation of Atherosclerotic Plaques in Abdominal CT Studies

 000037-CC:

Development and Evaluation of Techniques for Computer Aided Detection and Diagnosis from Existing Radiologic Images

 20-CC-0113:

Cardiopulmonary Inflammation and Multi-System Imaging During the Clinical Course of COVID-19 Infection in Asymptomatic and Symptomatic Persons (COVID ARC 19)

 20-CC-0031:

A single cohort study collecting interval timed incisional epidermal and dermal tissue samples during surgical procedures to profile temporal response of tissue after noxious stimuli.

 19-CC-0070:

Translational Development of Photon-Counting CT Imaging

 19-CC-0063:

Impact of Steady State Cobicistat and Darunavir/Cobicistat on the Pharmacokinetics and Pharmacodynamics of Oral Anticoagulants (Rivaroxaban, Apixaban) in Healthy Volunteers

 18-CC-0117:

PET Imaging of the Dopaminergic and Serotonergic Systems in Treated HIV Positive Subjects

 18-CC-0087:

Impact of Weekly Administration of Rifapentine and Isoniazid on Steady State Pharmacokinetics of Tenofovir Alafenamide in Healthy Volunteers

 18-CC-0079:

Pilot RCT of Web-based Behavioral Sleep Intervention for Individuals with Alcohol Use Disorder

 17-CC-0111:

Pilot Study Characterizing Aerobic Exercise in Women with Systemic Lupus Erythematosus (Exercise SLE Pilot).

 16-CC-0168:

Focus Groups to Determine Surrogates' Views Regarding Patient Preference Predictors

 16-CC-0162:

Longitudinal Changes in the Oral and Gut Microbiome of Individuals with Alcohol Dependence

 16-CC-0098:

Pilot Study of Ultrasound Guided Focal Thermal Ablation of Prostate Cancer

 16-CC-0049:

A Phase II Study Using LC Bead LUMI Radio-Opaque Embolic Beads to Detect and Characterize the Vascularity of Hepatic Tumors During Treatment with Transarterial Embolization (TAE) Alone or Combined with Thermal Ablation

 16-CC-0001:

Evaluation of MiSeq for Microbial Identification in Specimens

 15-CC-0164:

Effect of Exercise Training on Physical, Cognitive and Behavioral Function in Patients with Traumatic Brain Injury

 14-CC-0201:

A Randomized Controlled Trial to Determine the Effectiveness of a Stress Reduction Intervention in Caregivers of Allogeneic Hematopoietic Stem Cell Transplant (HSCT) Recipients

 14-CC-0143:

Sleep Disturbance and Relapse in Individuals with Alcohol Dependence: An Exploratory Mixed Methods Study

 14-CC-0027:

The NIH Exercise Therapy for Advanced Lung Disease Trials: Response and Adaptation to Aerobic Exercise in Patients with Interstitial Lung Disease

 11-CC-0152:

The Natural History of Liver Disease in a Cohort of Participants with Hepatitis B and/or Hepatitis C with or without HIV Infection

 11-CC-0120:

Stereophotogrammetry of the Torso in Healthy Individuals and Patients with Scoliosis, Chest Wall Deformations, or Obesity

 11-CC-0088:

Effect of Aerobic Exercise Training on Cardiorespiratory Fitness in Patients with Traumatic Brain Injury

 10-CC-0217:

A Comparison of Methods for Assisting Needle Angle Selection During Image-Guided Tissue Biopsy

 10-CC-0150:

Effects of Rapid-Resisted Exercise on Ambulatory Adults with Traumatic Brain Injury

 10-CC-0149:

Comparing Expectorated and Induced Sputum and Pharyngeal Swabs for Cultures, AFB Smears, and Cytokines in Pulmonary Nontuberculous Mycobacterial Infection

 10-CC-0053:

Collection of Bone Marrow from Healthy Volunteers and Patients for the Production of Clinical Bone Marrow Stromal Cells (BMSC)Products

 09-CC-0217:

Vasti Control of Patellofemoral Kinematics in Asymptomatic Volunteers

 08-CC-0133:

Response and Adaptation to Aerobic Exercise in Patients with Pulmonary Hypertension: Initial Studies for Establishing Guidelines

 05-CC-0216:

Prospective Assessment of Functional Status, Psychosocial Adjustment, Health Related Quality of Life and the Symptom Experience in Patients Treated with Allogeneic Hematopoietic Stem Cell Transplantation

 05-CC-0041:

Endothelial Cell Dysfunction in Pulmonary Arterial Hypertension: Biomarkers, Mechanisms of Disease and Novel Therapeutic Targets

 02-CC-0266:

Acute Cardiac Allograft Cellular Rejection and Cardiac Allograft Vasculopathy: Identification of Diagnostic Biomarkers and Target Pathways for Preventive Therapy

 01-CC-0231:

A Prospective Study of Transfusion-Transmitted Infections

 01-CC-0045:

Studies of Phlebotomy Therapy in Hereditary Hemochromatosis

 91-CC-0117:

Epidemiology, Infectivity and Natural History of Hepatitis C Virus Infection in a Blood Donor Population