This study is NOT currently recruiting participants.
Number
15-H-0017
Sponsoring Institute
National Heart, Lung and Blood Institute (NHLBI)
Recruitment Detail
Type: Completed Study; data analyses ongoing Gender: Male & Female Min Age: 18 Years Max Age: 100 Years
Referral Letter Required
No
Population Exclusion(s)
Children
Keywords
Idiopathic Pulmonary Fibrosis; Apoliprotein A-1; Natural History
Recruitment Keyword(s)
None
Condition(s)
Idiopathic Pulmonary Fibrosis
Investigational Drug(s)
Investigational Device(s)
Intervention(s)
Supporting Site
National Heart, Lung, and Blood Institute
- Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease that becomes worse over time. There is currently no effective treatment for it. Researchers want to study the disease and learn new ways to treat it.
Objectives:
- To discover new pathways that are involved in pulmonary fibrosis. To develop new drugs that may be used to treat pulmonary fibrosis.
Eligibility:
- People at least 18 years old with IPF.
- Healthy volunteers at least 18 years old.
Design:
- Participants will be screened with medical history, questionnaire, and physical exam. They will have blood, lung, and walking tests and chest scans.
- All participants will have 1 study visit, including:
- Medical history and physical exam.
- Questions about their breathing.
- Blood tests.
- Breathing tests.
- Six-minute walk test.
- Pregnancy test.
- Chest x-ray (healthy volunteers) or chest CT scan (people with pulmonary fibrosis ).
- Small area of skin may be removed.
- Genetic tests of blood and skin samples. Participants will probably not be informed of any findings. Samples may be used to make stem cells for use in research. Participants may be contacted in the future to give consent for this research.
- Some participants will have repeat visits over many years, repeating many of the study tests.
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INCLUSION CRITERIA: Patient: Males and females over the age of 18 with a diagnosis of IPF. EXCLUSION CRITERIA: Patient: Female subjects who are pregnant or lactating INCLUSION CRITERIA: Normal Volunteer: Males and females over the age of 18 without IPF. EXCLUSION CRITERIA: Normal Volunteer: Female subjects who are pregnant or lactating
Patient:
Males and females over the age of 18 with a diagnosis of IPF.
EXCLUSION CRITERIA:
Female subjects who are pregnant or lactating
INCLUSION CRITERIA:
Normal Volunteer:
Males and females over the age of 18 without IPF.
Principal Investigator
Referral Contact
For more information: