This study is currently recruiting participants.
National Cancer Institute (NCI)
Type: Participants currently recruited/enrolled Gender: Male Min Age: 18 Years Max Age: N/A
Referral Letter Required
Genetic; Prostatic Neoplasms; Genotyping; Venipuncture; Polymorphism; Natural History
Cancer Of Prostate; Prostate Cancer; Prostatic Neoplasms; Metastatic Prostate Cancer; Prostate
National Cancer Institute
-It is not fully understood why prostate cancer in some men becomes androgen-independent (no longer responds to anti-androgen medication), but genetics likely plays an important role.
-Genes contain the hereditary information that is passed down from parents to children. Although everyone has the same set of genes, individuals can have different forms of the same gene.
-Differences in genes may explain, at least in part, why some people develop a more aggressive form of prostate cancer than others.
-To obtain blood samples from patients with prostate cancer to try to identify gene differences associated with progression to the androgen independent state.
-All participants participating in NCI prostate cancer protocols.
-Participants with prostate cancer are evaluated in the NCI s Medical Oncology Clinic.
-Blood samples are collected at the initial visit or at follow-up visits.
-DNA (genetic material) and white blood cells are extracted from these samples to be used for genotyping and establishment of cell lines.
-Gene variations are correlated with prostate cancer prognosis and prognostic indicators.
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INCLUSION CRITERIA: Patients 18 years of age and older are eligible. Patients with a diagnosis of prostate cancer are eligible. EXCLUSION CRITERIA: Children are not eligible.
Patients 18 years of age and older are eligible.
Patients with a diagnosis of prostate cancer are eligible.
Children are not eligible.
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