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Protocol Details

Human Specimen Collection to Support Basic and Clinical Research

This study is currently recruiting participants.

Summary | Eligibility | Citations | Contacts

Summary

Number

03-H-0015

Sponsoring Institute

National Heart, Lung and Blood Institute (NHLBI)

Recruitment Detail

Type: Participants currently recruited/enrolled
Gender: Male & Female
Min Age: 18 Years
Max Age: 100 Years

Referral Letter Required

No

Population Exclusion(s)

Children

Keywords

DNA;
Endothelial Function;
Leukocyte Gene Expression;
RNA;
Natural History

Recruitment Keyword(s)

Sickle Cell;
Coronary Artery Disease;
CAD;
Healthy Volunteer;
HV

Condition(s)

Sickle Cell Disease

Investigational Drug(s)

None

Investigational Device(s)

None

Intervention(s)

None

Supporting Site

National Heart, Lung and Blood Institute

The collection of human specimens from both patients and healthy volunteers is necessary for the development of laboratory assays to further basic and clinical research studies. This protocol defines the purposes for which specimens will be collected and establishes general conditions under which sample collection will be performed.

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Eligibility

INCLUSION CRITERIA:

Males or females of age 18 years and older can be included in the study.

EXCLUSION CRITERIA:

Individuals without sickle cell disease or other chronic anemias who wish to donate blood will be excluded if the hemoglobin is less than 10 g/dL for women or less than 12g/dL for men.

Individuals with sickle cell disease or other chronic anemias will be excluded from donating blood samples if the hemoglobin is less than 6 g/dL.

A participant s most recent CBC result, obtained in the past 12 months, will be used to determine eligibility.

There are no exclusion criteria for participants donating saliva or urine.


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Citations:

Not Provided

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Contacts:

Principal Investigator

Referral Contact

For more information:

Swee Lay Thein, M.D.
National Heart, Lung and Blood Institute (NHLBI)
NIHBC 10 - CLINICAL CENTER BG RM 6S241A
10 CENTER DR
BETHESDA MD 20892
(301) 435-2345
sweelay.thein@nih.gov

Anna K. Conrey, C.R.N.P.
National Heart, Lung and Blood Institute (NHLBI)
NIHBC 10 - CLINICAL CENTER BG RM 6N240D
10 CENTER DR
BETHESDA MD 20892
(301) 221-3016
anna.conrey@nih.gov

Office of Patient Recruitment
National Institutes of Health Clinical Center (CC)
Building 61, 10 Cloister Court
Bethesda, Maryland 20892
Toll Free: 1-800-411-1222
Local Phone: 301-451-4383
TTY: TTY Users Dial 7-1-1
ccopr@nih.gov

Clinical Trials Number:

NCT00047996

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