This study is NOT currently recruiting participants.
Number
02-N-0014
Sponsoring Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Recruitment Detail
Type: Completed Study; data analyses ongoing Gender: Male & Female Min Age: 4 Max Age: N/A
Referral Letter Required
Yes
Population Exclusion(s)
None
Keywords
Serotonin Receptor; Cell Culture; Temporal Lobe; Endothelial Cells; Superficial Temporal Artery; Natural History
Recruitment Keyword(s)
Epilepsy; Intractable Epilepsy
Condition(s)
Epilepsy
Investigational Drug(s)
Investigational Device(s)
Intervention(s)
Supporting Site
National Institute of Neurological Disorders and Stroke
Patients 4 years of age or older who undergo surgery for medically intractable epilepsy may be eligible for this study.
Brain tissue collected under this protocol will be used for studies of brain cells in other diseases and of serotonin receptors. Any remaining brain tissue will be frozen for use in future research. The superficial temporal artery will be used for comparison with carotid arteries (a neck artery that supplies the brain) from patients with blockage of this blood vessel.
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INCLUSION CRITERIA: To be eligible for entry into the study, candidates must meet al the following criteria: 1. Be 4 years of age or older. 2. Able to give informed consent, or, assent if a child. 3. Have agreed to undergo brain surgery to treat drug resistant epilepsy and are enrolled in protocol 11-N-0051 Epilepsy Surgery. EXCLUSION CRITERIA: Candidates will be excluded if they: 1. Are not a surgical candidate as specified in appropriate protocols.
To be eligible for entry into the study, candidates must meet al the following criteria:
1. Be 4 years of age or older.
2. Able to give informed consent, or, assent if a child.
3. Have agreed to undergo brain surgery to treat drug resistant epilepsy and are enrolled in protocol 11-N-0051 Epilepsy Surgery.
EXCLUSION CRITERIA:
Candidates will be excluded if they:
1. Are not a surgical candidate as specified in appropriate protocols.
Principal Investigator
Referral Contact
For more information: