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Protocol Details

Collection of Peripheral Blood and/or Urine From Patients Undergoing Radiation Therapy

This study is currently recruiting participants.

Summary | Eligibility | Citations | Contacts

Summary

Number

02-C-0064

Sponsoring Institute

National Cancer Institute (NCI)

Recruitment Detail

Type: Enrolling by Invitation
Gender: Male & Female
Min Age: 18 Years
Max Age: N/A

Referral Letter Required

No

Population Exclusion(s)

Children

Keywords

Blood;
Samples;
Radiation;
Urine;
Cancer;
Natural History

Recruitment Keyword(s)

None

Condition(s)

Carcinoma;
Cancer;
Tumor

Investigational Drug(s)

None

Investigational Device(s)

None

Intervention(s)

None

Supporting Site

National Cancer Institute

Background:

-Research in NCI's Radiation Oncology Branch depends on the availability of blood and urine samples from patients receiving radiation therapy.

Objectives:

-To explore the effects of radiation therapy on gene expression in white blood cells, to measure radiation damage in red blood cells and to examine changes in hormone levels in the blood and urine after radiation therapy.

Eligibility:

-Patients 18 years of age and older who are receiving radiation therapy.

Design:

-Blood and urine samples are collected when participants enter the study.

-Additional samples may be collected at different times during and after treatment. Ideally, samples are obtained before, at the completion of, and 1 month following radiation therapy. Blood samples usually will be collected during routine patient monitoring procedures and will not require an additional needle stick.

-A total of 300 patients will be studied at the NCI in Bethesda, MD, Johns Hopkins University in Baltimore and the University of Pennsylvania in Philadelphia.

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Eligibility

INCLUSION CRITERIA:

1. Patients must be co-enrolled in a NIH CC protocol in which radiation will be administered.

2. Patients must a candidate for, or currently receiving radiotherapy.

3. Age greater than or equal to 18 years.

4. Ability of subject or Legally Authorized Representative (LAR) to understand and the willingness to sign a written informed consent document.

EXCLUSION CRITERIA:

1. Patients who have unobtainable data regarding previous radiation therapy.


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Citations:

Not Provided

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Contacts:

Principal Investigator

Referral Contact

For more information:

Kevin A. Camphausen, M.D.
National Cancer Institute (NCI)
NIHBC 10 - CRC BG RM B2-3675
10 CENTER DR
BETHESDA MD 20892
(240) 760-6205
camphauk@mail.nih.gov

Debbie Nathan, R.N.
National Cancer Institute (NCI)
National Institutes of Health
Building 10
Room 2-1730
10 Center Drive
Bethesda, Maryland 20892
(301) 451-8968
dnathan@mail.nih.gov

NCI Referral Office
National Institute of Health Clinical Center (CC), 9000 Rockville Pike, Bethesda, Maryland 20892, United States: NCI Clinical Trials Referral Office
1-888-NCI-1937

Clinical Trials Number:

NCT00027326

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