This study is currently recruiting participants.
Number
000849-CH
Sponsoring Institute
National Institute of Child Health and Human Development (NICHD)
Recruitment Detail
Type: Participants currently recruited/enrolled Gender: Male & Female Min Age: 18 Years Max Age: 110 Years
Referral Letter Required
No
Population Exclusion(s)
Pregnant Women;Children
Keywords
Optical Technique; Pulse Transit Time; Pearson Correlation Coefficient; Spg Waveform; Signal Quality; Natural History
Recruitment Keyword(s)
None
Condition(s)
Blood Pressure
Investigational Drug(s)
Investigational Device(s)
Intervention(s)
Supporting Site
National Institute of Child Health and Human Development
Blood pressure is one of the key markers of cardiovascular health. High blood pressure, also called hypertension, can increase the risk of heart disease or stroke. Monitoring a person s blood pressure continuously over a 24-hour period at home is the best way to diagnose hypertension, but the equipment currently used to do it is cumbersome. This natural history study will test a new technique for monitoring blood pressure continuously over time.
Objective:
To test a new technique (speckle plethysmography) for measuring blood pressure in healthy adults.
Eligibility:
Healthy people aged 18 years and older.
Design:
Participants will come to the clinic a minimum of 2 times.
The screening visit will last up to 2 hours. Participants will have a physical exam. Their vital signs will be taken.
The clinical visit will last up to 1 hour. Participants will recline in a chair. Sensors to measure the activity of the heart will be placed on their chest. Different sensors will be placed on two fingers and one big toe. A device to measure blood pressure will be placed on one arm.
While wearing the sensors, participants will undergo 3 tests:
They will be asked to breathe slowly for 2 minutes.
They will be asked to solve a math problem.
They will immerse one hand or foot into an ice bath for up to 2 minutes.
Each test will be followed by a 5-minute recovery period.
Participants may elect to return for up to 3 more visits during the following week.
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INCLUSION CRITERIA: In order to be eligible to participate in this study, an individual must meet all of the following criteria: - Male or female, aged 18 or greater. - In good general health as evidenced by medical history and physical. EXCLUSION CRITERIA: An individual who meets any of the following criteria will be excluded from participation in this study: - Any active cardiovascular or pulmonary disorders or use of vasoactive medications. - History of aneurysm or stroke. - Pregnant by history. - History of fainting or seizures. - An open cut, sore, or bone fracture on or near the hands or feet. - Known retinopathy, intraocular lens implantation, or glaucoma. - Any other condition that in the opinion of the investigator would place the participant at unacceptable risk.
In order to be eligible to participate in this study, an individual must meet all of the following criteria:
- Male or female, aged 18 or greater.
- In good general health as evidenced by medical history and physical.
EXCLUSION CRITERIA:
An individual who meets any of the following criteria will be excluded from participation in this study:
- Any active cardiovascular or pulmonary disorders or use of vasoactive medications.
- History of aneurysm or stroke.
- Pregnant by history.
- History of fainting or seizures.
- An open cut, sore, or bone fracture on or near the hands or feet.
- Known retinopathy, intraocular lens implantation, or glaucoma.
- Any other condition that in the opinion of the investigator would place the participant at unacceptable risk.
Principal Investigator
Referral Contact
For more information: