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385 Studies found from all possible combinations of your search terms. Select a protocol that you wish to review.
Protocol Number
Title
Protocol Status
Min-Max Age
Institute
Keywords
000726-C
A Randomized Phase 2 Study of Atezolizumab with or without Selinexor in Alveolar Soft Part Sarcoma (AXIOM)
Participants currently recruited/enrolled
18-125 Years
NCI
Soft Tissue Sarcoma
000475-C
Phase 2 Study of Rogaratinib (BAY 1163877) in the Treatment of Patients with Sarcoma Harboring Alterations in Fibroblast Growth Factor Receptor (FGFR) 1-4 and SDH-deficient Gastrointestinal Stromal Tumor (GIST)
Participants currently recruited/enrolled
18-125 Years
NCI
Soft Tissue Sarcoma
21-C-0022
A Phase 2 Single Arm Open-Label Clinical Trial of ADP-A2M4 SPEAR(TM) T Cells in Subjects with Advanced Synovial Sarcoma or Myxoid/Round Cell Liposarcoma
Participants currently recruited/enrolled
10-75 Years
NCI
Soft Tissue Sarcoma
19-C-0061
A Phase 2 Trial of the MEK Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in Combination with the mTOR Inhibitor Sirolimus for Patients with Unresectable or Metastatic Malignant Peripheral Nerve Sheath Tumors
Participants currently recruited/enrolled
12-125 Years
NCI
Soft Tissue Sarcoma
19-C-0016
Natural History and Biospecimen Acquisition Study for Children and Adults with Rare Solid Tumors
Participants currently recruited/enrolled
0-125 Years
NCI
Soft Tissue Sarcoma
17-C-0049
A Phase I/II Trial of the Insulin-Like Growth Factor 1 Receptor (IGF-1R) Antibody AMG479 (Ganitumab) in Combination with the Src Family Kinase (SFK) Inhibitor Dasatinib in Patients with Embryonal and Alveolar Rhabdomyosarcoma
Completed Study; data analyses ongoing
2-125 Years
NCI
Soft Tissue Sarcoma
13-C-0044
A Phase 2 Study of Cabozantinib (XL184), a Dual Inhibitor of MET and VEGFR, in Patients With Metastatic Refractory Soft Tissue Sarcoma
No longer recruiting/follow-up only
18-120 Years
NCI
Soft Tissue Sarcoma
11-C-0200
A Phase II Trial In Which Patients With Metastatic Alveolar Soft Part Sarcoma Are Randomized to Either Sunitinib or Cediranib Monotherapy, with Cross-Over at Disease Progression
No longer recruiting/follow-up only
16-125 Years
NCI
Soft Tissue Sarcoma
09-C-0192
Phase II Study of Cediranib (AZD2171) in Patients With Alveolar Soft Part Sarcoma
No longer recruiting/follow-up only
0-125 Years
NCI
Soft Tissue Sarcoma
001043-I
Evaluating the Genetics and Immunology of Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis (PFAPA) Syndrome and Other Tonsil Disorders
Recruitment has not started
0-125 Years
NIAID
Soft Tissue
000975-C
Collection of Blood, Bone Marrow, Skin, Saliva, and Stool Samples from Healthy Volunteers Used for Comparative Analysis of Myeloid Malignancies
Participants currently recruited/enrolled
18-125 Years
NCI
Soft Tissue
000732-C
A Long-Term Follow-Up Study of Patients Who Received VOR33
Recruitment has not started
18-125 Years
NCI
Soft Tissue
000224-CH
Development of a Wearable Point of Care Monitoring Device for Pediatric Obstructive Sleep Apnea
Participants currently recruited/enrolled
3-12 Years
NICHD
Soft Tissue
000206-CH
Endometrial Basis for Infertility in Women with Recurrent Implantation Failure and Pregnancy Loss
Participants currently recruited/enrolled
18-42 Years
NICHD
Soft Tissue
21-C-0032
GD2-CAR PERSIST: Production and Engineering of GD2-Targeted, Receptor Modified T Cells (GD2CART) for Osteosarcoma or Neuroblastoma to Increase Systemic Tumor Exposure
Participants currently recruited/enrolled
0-35 Years
NCI
Tissue Sarcoma
20-C-0161
Prospective Study of Surgery in Gastrointestinal Stromal Tumors (GISTs) for Treatment, Tumor Modeling, and Genomic Analysis
Participants currently recruited/enrolled
6-125 Years
NCI
Tissue Sarcoma
20-C-0061
Phase I/II study of NHS-IL12 Monotherapy and in Combination with M7824 in Advanced Kaposi Sarcoma
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue Sarcoma
19-C-0010
A Phase 1 Trial of MK-3475 Plus Ziv-Aflibercept in Patients with Advanced Solid Tumors
Completed Study; data analyses ongoing
18-125 Years
NCI
Tissue Sarcoma
17-C-0174
Molecular Characterization of Viral-associated Tumors, Tumors Occurring in the Setting of HIV or Other Immune Disorders and Castleman Disease
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue Sarcoma
17-C-0074
A Phase 2 Study of Anti-PD-L1 Antibody Atezolizumab in Alveolar Soft Part Sarcoma
Participants currently recruited/enrolled
2-125 Years
NCI
Soft Sarcoma
16-C-0047
A Phase 1 Trial of Pomalidomide in Combination with Liposomal Doxorubicin in Patients with Advanced or Refractory Kaposi Sarcoma
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue Sarcoma
12-H-0110
An Open-label, Non-Randomized, Single-Arm Pilot Study to Evaluate the Effectiveness of Etidronate Treatment for Arterial Calcifications due to Deficiency in CD73 (ACDC)
Completed Study; data analyses ongoing
18-80 Years
NHLBI
Soft Tissue
11-C-0220
Natural History Study of the KSHV Inflammatory Cytokine Syndrome (KICS) Incorporating Pilot Evaluation of KSHV Targeted Therapies
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue Sarcoma
10-C-0086
Comprehensive Omics Analysis of Pediatric Solid Tumors and Establishment of a Repository for Related Biological Studies
Participants currently recruited/enrolled
0-125 Years
NCI
Tissue Sarcoma
09-I-0200
A Phase I Study of MozobilTM in the Treatment of Patients with WHIMS
Participants currently recruited/enrolled
18-75 Years
NIAID
Soft Tissue
02-I-0110
Natural History of Anthrax: A Study of Primary Infected, Recovered, and Exposed (SPoRE) Individuals and Evaluation of AVA Vaccinated Recipients
Participants currently recruited/enrolled
3-125 Years
NIAID
Soft Tissue
02-C-0313
Cancer Risk in Xeroderma Pigmentosum Heterozygotes
Participants currently recruited/enrolled
0-99 Years
NCI
Soft Tissue
02-C-0211
Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of Melanoma
Participants currently recruited/enrolled
2-125 Years
NCI
Soft Tissue
01-C-0038
Collection of Blood, Bone Marrow, Tumor, or Tissue Samples from Patients with HIV Infection, KSHV Infection, Viral-Related Pre-Malignant Lesions, and/or Cancer
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue Sarcoma
94-I-0079
Eosinophil Activation and Function in Parasitic Infections and Other Conditions with Increased Tissue or Peripheral Blood Eosinophilia in Humans
Participants currently recruited/enrolled
1-100 Years
NIAID
Soft Tissue
001516-C
Phase I Study of Aerosolized Antibiotics and Pembrolizumab in Advanced Non-Small Cell Lung Cancer
Recruitment has not started
10-120 Years
NCI
Tissue
001146-I
A Repository to Study Host-Microbiome Interactions in Health and Disease
Participants currently recruited/enrolled
0-125 Years
NIAID
Tissue
001126-DC
Collection of Clinical Data and Specimens for Research in Hearing, Balance and Communication Disorders
Participants currently recruited/enrolled
2-125 Years
NIDCD
Tissue
001099-C
A Phase 1/2, First-in-Human, Open-Label, Dose Escalation and Expansion Study of STAR0602, a Selective T Cell Receptor (TCR)-Targeting, Bifunctional Antibody-Fusion Molecule, in Subjects with Unresectable, Locally Advanced, or Metastatic Solid Tumors that
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
001084-CH
A Prospective Natural History Study of Lymphatic Anomalies
Participants currently recruited/enrolled
0-125 Years
NICHD
Tissue
001032-C
BAY 1895344 Plus Topoisomerase-1 (Top1) Inhibitors in Patients with Advanced Solid Tumors, Phase I Studies with Expansion Cohorts in Small Cell Lung Carcinoma (SCLC), Poorly Differentiated Neuroendocrine Carcinoma (PD-NEC) and Pancreatic Adenocarcinoma (
Recruitment has not started
18-125 Years
NCI
Tissue
001004-C
A Phase 1b/2 Basket Study of ACR-368 as Monotherapy and in Combination with Gemcitabine in Adult Subjects with Platinum-Resistant Ovarian Carcinoma, Endometrial Adenocarcinoma, and Urothelial Carcinoma Based on Acrivon Oncosignature (R) Status
Participants currently recruited/enrolled
18-120 Years
NCI
Tissue
000977-I
Phase I/II Study using Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Granulomatous Disease with an Alemtuzumab, Busulfan and TBI-based Conditioning Regimen Combined with Cytokine (IL-6, +/- IFN-gamma) Antagonists
Participants currently recruited/enrolled
4-65 Years
NIAID
Tissue
000958-C
Prospective Procurement of Tumor Tissue to Identify Novel Therapeutic Targets and Study the Tumor Microenvironment
Enrolling by Invitation
18-125 Years
NCI
Tissue
000894-AR
Natural History of Inflammatory Muscle Diseases
Recruitment has not started
12-125 Years
NIAMS
Tissue
000861-I
A Phase 2 Open-Label Study to Evaluate the Efficacy and Safety of Ruxolitinib on Hair Regrowth in Patients with Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy (APECED)-Associated Alopecia Areata
Participants currently recruited/enrolled
12-65 Years
NIAID
Tissue
000844-H
Exploring Near Infrared Spectroscopy (NIRS) Technologies for Assessment of Muscle Physiology, Tissue Oxygenation, and Blood Flow in Patients with Sickle Cell Disease (SCD)
Participants currently recruited/enrolled
18-125 Years
NHLBI
Tissue
000827-AR
Natural History and Pathogenesis of Alopecia in Children and Adults
Participants currently recruited/enrolled
2-45 Years
NIAMS
Soft
000809-I
A Pilot Study of Fecal Microbiota Transplantation for Chronic Granulomatous Disease-Associated Colitis
Participants currently recruited/enrolled
10-60 Years
NIAID
Tissue
000798-D
A Phase 2 Study of Burosumab for Fibroblast Growth Factor-23 Mediated Hypophosphatemia in Fibrous Dysplasia
Participants currently recruited/enrolled
1-125 Years
NIDCR
Tissue
000792-C
A Multicenter Study to Evaluate Next-Generation Sequencing (NGS) Testing and Monitoring of B-Cell Recovery to Guide Management Following Chimeric Antigen Receptor T-cell (CART) Induced Remission in Children and Young Adults with B Lineage Acute Lymphobla
Recruitment has not started
1-25 Years
NCI
Tissue
000781-I
A Phase III, Adjudicator-Blinded, Randomised Study to Evaluate the Efficacy and Safety of Treatment with Olorofim Versus Treatment with AmBisome(R) Followed by Standard of Care (SOC) in Patients with Invasive Fungal Disease (IFD) Caused by Aspergillus Sp
Participants currently recruited/enrolled
18-125 Years
NIAID
Tissue
000757-DK
Natural History of Pregnancy and Pregnancy Outcomes in Metreleptin-Treated vs Untreated Subjects with Lipodystrophy
Participants currently recruited/enrolled
0-125 Years
NIDDK
Tissue
000756-DK
Phase II Study of Growth Hormone Inhibition Using Pegvisomant In Severe Insulin Resistance
Participants currently recruited/enrolled
18-65 Years
NIDDK
Tissue
000736-CC
Imaging Characterization of the Biomechanical Coupling of Brain and Skull: An Observational Study
Participants currently recruited/enrolled
21-65 Years
CC
Tissue
000715-CH
Biorepository in Participants Who Undergo OTC for Gonadotoxic Therapy
Participants currently recruited/enrolled
4-35 Years
NICHD
Tissue
000707-I
Respiratory Virus Sampling and Repository
Participants currently recruited/enrolled
3-125 Years
NIAID
Soft
000666-C
A Phase I/II Study of Palbociclib and Sasanlimab for the Treatment of Advanced Clear Cell Renal Cell Carcinoma (ccRCC) or Papillary Renal Cell Carcinoma (pRCC)
Recruitment has not started
18-125 Years
NCI
Tissue
000612-C
Phase 1 Study of NT-I7 (rhIL-7-hyFc) for the Treatment of Kaposi Sarcoma in Patients With or Without Infection with HIV
Participants currently recruited/enrolled
18-125 Years
NCI
Sarcoma
000545-DK
Prevalence and Development of Liver Dysfunction in Hematopoietic Stem Cell Transplant: A Prospective Natural History Study
Recruitment has not started
3-125 Years
NIDDK
Tissue
000491-C
Tissue Procurement and Natural History Study of Neuroendocrine Neoplasms (NENs) Including Adrenocortical Carcinoma (ACC)
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
000473-C
A Randomized Phase II Study of Systemic Chemotherapy with or without HAI FUDR-Dexamethasone in Patients with Unresectable Intrahepatic Cholangiocarcinoma
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
000464-H
Evaluation of Clonal Hematopoiesis in Patients with Sickle Cell Disease Receiving Curative Therapies
Enrolling by Invitation
4-125 Years
NHLBI
Tissue
000350-D
Use of Clear Aligners for the Treatment of Dental Malocclusion In Individuals with Osteogenesis Imperfecta Types III and IV
Participants currently recruited/enrolled
12-40 Years
NIDCR
Tissue
000344-DK
Natural History Study of Parathyroid Disorders
Participants currently recruited/enrolled
0-125 Years
NIDDK
Tissue
000343-H
Detection of T cell Somatic Mutations in Bone Marrow Failure Using Whole Exome or Targeted Sequencing
Enrolling by Invitation
18-125 Years
NHLBI
Tissue
000337-C
Natural History Study of KSHV-Associated Multicentric Castleman's Disease
Participants currently recruited/enrolled
18-125 Years
NCI
Sarcoma
000324-C
Phase 1/2 Dose Escalation Study of CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults with Recurrent or Refractory CD19/CD22-expressing B Cell Malignancies
Participants currently recruited/enrolled
3-35 Years
NCI
Tissue
000305-C
Exploratory Phase II Study of LAnreotide in Unresectable or Metastatic Pheochromocytoma / PARAganglioma
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
000302-C
A Multi-Center Natural History of Urothelial Cancer and Rare Genitourinary Tract Malignancies
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
000281-I
Pilot Assessment To Find Evidence of Gastric Motility Abnormalities in Eosinophilic Gastric Disorders (OAT-FEED)
Participants currently recruited/enrolled
18-59 Years
NIAID
Tissue
000277-C
Imaging and Biopsy of HIV-Infected Individuals Undergoing Analytic Treatment Interruption
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
000274-C
Phase I Trial of Pomalidomide and Dose-Adjusted EPOCH +/- Rituximab for HIV-Associated Lymphomas
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
000247-DK
Evaluation of Patients with Gastrointestinal Disease
Participants currently recruited/enrolled
18-125 Years
NIDDK
Tissue
000237-C
Phase II Study of Intravenous and Intraperitoneal Paclitaxel and Oral Nilotinib for Peritoneal Carcinomatosis from Colorectal, Appendiceal, Small Bowel, Gastric, Ovarian, or Other Gynecologic Primary Cancer
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
000236-I
A Phase 1 Study of Empagliflozin as Treatment for Severe Congenital Neutropenia Due to G6PC3 Deficiency
Participants currently recruited/enrolled
18-125 Years
NIAID
Tissue
000213-HG
Clinical and Laboratory Study of Rare Skeletal Disorders
Participants currently recruited/enrolled
0-125 Years
NHGRI
Tissue
000193-C
Phase 1 Study of Copanlisib with Dose-adjusted EPOCH-R in Relapsed and Refractory Burkitt Lymphoma and other High-Grade B-cell Lymphomas
Clinical hold/Recruitment or enrollment suspended
18-125 Years
NCI
Tissue
000187-EI
Adaptive Optics Imaging of Outer Retinal Diseases
Participants currently recruited/enrolled
21-125 Years
NEI
Soft
000173-C
Systematically Assessing Changes in Plexiform Neurofibroma Related Disfigurement from Photographs of Subjects with Neurofibromatosis Type 1 on a Phase 2 Clinical Trial
Completed Study; data analyses ongoing
7-125 Years
NCI
Tissue
000141-DC
Deep Phenotyping of Hearing Instability Disorders: Cohort Establishment, Biomarker Identification, Development of Novel Phenotyping Measures, and Discovery of Therapeutic Targets
Participants currently recruited/enrolled
18-80 Years
NIDCD
Soft
000130-DK
Unraveling the Mechanisms Underlying Primary Sclerosing Cholangitis Through a Multidisciplinary, Integrative Research Approach
Participants currently recruited/enrolled
18-125 Years
NIDDK
Tissue
000126-N
A Pilot Study of NT-I7, a Long-Acting Recombinant IL-7 Molecule, as an Immune Reconstitution Strategy for Lymphopenia in Patients with Progressive Multifocal Leukoencephalopathy
Participants currently recruited/enrolled
18-125 Years
NINDS
Soft
000106-CH
Gonadal Tissue Freezing for Fertility Preservation in Individuals at risk for Ovarian Dysfunction and Premature Ovarian Insufficiency
Participants currently recruited/enrolled
4-21 Years
NICHD
Tissue
000094-N
An Observational Study of Neurologic Function After COVID -19 Infection
No longer recruiting/follow-up only
18-125 Years
NINDS
Soft
000092-C
Phase 1/2 study of Vincristine and Temozolomide in Combination with PEN-866 for Adolescents and Young Adults with Relapsed or Refractory Solid Tumors
Recruitment has not started
12-39 Years
NCI
Sarcoma
000081-C
A Phase 2 Study of Anti-PD-L1 Antibody (Atezolizumab) in Chondrosarcoma and Clear Cell Sarcoma
Completed Study; data analyses ongoing
2-125 Years
NCI
Sarcoma
000064-I
A Phase 1/2 Open-label Study to Evaluate the Safety and Efficacy of Tofacitinib for Chronic Granulomatous Disease with Inflammatory Complications
Enrolling by Invitation
18-125 Years
NIAID
Tissue
000062-C
Phase I Evaluation of Immunotoxin LMB-100 Administered by Normothermic, Intrapleural Perfusion Following Cytoreductive Surgery in Participants with Pleural Mesotheliomas, or Pleural Effusions from Cancers Expressing Mesothelin
Participants currently recruited/enrolled
18-120 Years
NCI
Tissue
000059-C
Phase I Study of Intratumor Injection of anti-Mesothelin Immunotoxin LMB-100 with Ipilimumab in Malignant Mesothelioma
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
000046-C
Omics of Cancer: OncoGenomics
Recruitment has not started
0-125 Years
NCI
Tissue
000037-CC
Development and Evaluation of Techniques for Computer Aided Detection and Diagnosis from Existing Radiologic Images
No longer recruiting/follow-up only
0-125 Years
CC
Soft
22-C-0005
Phase I Dose Escalation and Expansion Study of Tazemetostat in Combination with Topotecan and Pembrolizumab in Recurrent Small Cell Lung Cancer
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
22-C-0003
Feasibility of Evaluating Abemaciclib Neuropharmacokinetics of Diffuse Midline Glioma Using Intratumoral Microdialysis
Participants currently recruited/enrolled
18-39 Years
NCI
Tissue
21-N-0010
A Phase 2 Clinical Trial of Tolebrutinib, a Brain-penetrant Bruton's Tyrosine Kinase Inhibitor, for the Modulation of Chronically Inflamed White Matter Lesions in Multiple Sclerosis
No longer recruiting/follow-up only
18-125 Years
NINDS
Soft
21-H-0027
Characterization of Tissue-Specific Immune Responses to Bronchoscopic Instillation of Mycobacterial Antigens into the Human Lung
Participants currently recruited/enrolled
18-64 Years
NHLBI
Tissue
21-CH-0028
A Pilot Study to Evaluate a Noninvasive Multimodal Biosensing Device for Screening and Monitoring Response to Treatment of Infectious Respiratory Diseases.
Participants currently recruited/enrolled
18-125 Years
NICHD
Tissue
21-C-0026
A Phase I/II Study of Abemaciclib in Patients with HIV-associated and HIV-negative Kaposi Sarcoma
Participants currently recruited/enrolled
18-125 Years
NCI
Sarcoma
21-C-0023
A Phase I Study of Pomalidomide and Nivolumab in Patients with Virus-Associated Malignancies With or Without HIV
Participants currently recruited/enrolled
18-125 Years
NCI
Sarcoma
21-C-0021
SARC037: A Phase I/II Study to Evaluate the Safety of Trabectedin Administered as a 1-Hour Infusion in Ewing Sarcoma Patients in Combination with Low Dose Irinotecan and 3'-Deoxy-3'-18F Fluorothymidine (18F-FLT) Imaging
Participants currently recruited/enrolled
6-125 Years
NCI
Sarcoma
21-C-0014
Phase 1 Study of Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid in Combination with Polatuzumab (ViPOR-P) in Relapsed/Refractory B-cell Lymphoma
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
21-C-0009
A Natural History Study of Children and Adults with Olfactory Neuroblastoma
Participants currently recruited/enrolled
3-125 Years
NCI
Tissue
20-N-0019
The Effect of Vorinostat on ACTH Producing Pituitary Adenomas in Cushing's Disease
Participants currently recruited/enrolled
18-125 Years
NINDS
Tissue
20-I-0132
A Multicentre, Randomised, Double-blind, Parallel-group, Placebo-controlled, 24-week Phase 3 Study with an Open-label Extension to Evaluate the Efficacy and Safety of Benralizumab in Patients with Hypereosinophilic Syndrome (HES)
Participants currently recruited/enrolled
12-130 Years
NIAID
Tissue
20-I-0096
VRC 611: A Phase 1 Safety and Pharmacokinetic Study to Evaluate a Human Monoclonal Antibody (mAb) VRC-HIVMAB0102-00-AB (CAP256V2LS) Administered via Subcutaneous and Intravenous Injection in Healthy Adults
No longer recruiting/follow-up only
18-60 Years
NIAID
Tissue
20-H-0158
Natural History Study: Gene First Approach to Connective Tissue Disease
Participants currently recruited/enrolled
2-100 Years
NHLBI
Tissue
20-EI-0026
An Observational Cross-Sectional Study of Virtual Reality Mobility Assessment of Functional Vision in Retinal Disease
Participants currently recruited/enrolled
5-125 Years
NEI
Tissue
20-DK-0079
A Randomized, Double-Blinded, Placebo-Controlled Study of REGN4661, A Leptin Receptor Agonist Antibody, In Patients with Generalized Lipodystrophy
No longer recruiting/follow-up only
12-125 Years
NIDDK
Tissue
20-DK-0067
A Phase 3, Matrix Design, Partially Double-Blind, Randomized Study of the Efficacy and Safety of 50 mg Lonafarnib/100 mg Ritonavir BID with and without 180 mcg PEG IFN-alfa-2a for 48 Weeks Compared with PEG IFN-alfa-2a Monotherapy and Placebo Treatment i
No longer recruiting/follow-up only
18-125 Years
NIDDK
Tissue
20-CH-0165
Androgen Receptor, Implications for Health and Wellbeing: Natural History Study of Individuals with Androgen Insensitivity
Participants currently recruited/enrolled
0-99 Years
NICHD
Tissue
20-CH-0126
Data Collection Study of Pediatric and Adolescent Gynecology Conditions
Participants currently recruited/enrolled
0-125 Years
NICHD
Tissue
20-CC-0113
Cardiopulmonary Inflammation and Multi-System Imaging During the Clinical Course of COVID-19 Infection in Asymptomatic and Symptomatic Persons (COVID ARC 19)
No longer recruiting/follow-up only
18-80 Years
CC
Soft
20-CC-0039
A Feasibility Study to Evaluate the Combination of Electromagnetic Tracking and Optical Imaging with Indocyanine Green (ICG) for Hepatic Biopsies
Enrolling by Invitation
18-125 Years
CC
Tissue
20-CC-0031
A single cohort study collecting interval timed incisional epidermal and dermal tissue samples during surgical procedures to profile temporal response of tissue after noxious stimuli.
Completed Study; data analyses ongoing
18-125 Years
CC
Tissue
20-C-0162
A Phase 1 Study of Venetoclax with Obinutuzumab and Magrolimab (VENOM) in Relapsed and Refractory Indolent B-cell Malignancies
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
20-C-0150
Phase II Randomized Trial of Bethesda Protocol Compared to Cambridge Method for Detection of Early Stage Gastric Cancer in CDH1 Mutation Carriers
Recruitment has not started
18-125 Years
NCI
Tissue
20-C-0069
A First-In-Human Phase I Single-Agent Dose-Escalation, Food Effect and Dose Expansion Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms
Participants currently recruited/enrolled
18-125 Years
NCI
Sarcoma
20-C-0062
A phase 1b Study of Nivolumab in Patients with Autoimmune Disorders and Advanced Malignancies (AIM-NIVO)
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
20-C-0022
Phase II trial of VB-111 in Combination with Nivolumab in Patients with Metastatic Colorectal Cancer (mCRC)
Completed Study; data analyses ongoing
18-125 Years
NCI
Soft
20-C-0012
A Phase I Study of Bintrafusp alfa (M7824) and NHS-IL12 (M9241) Alone and in Combination with Stereotactic Body Radiation Therapy (SBRT) in Adults with Metastatic Non-Prostate Genitourinary Malignancies
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
20-C-0011
Phase 1 Study of Recombinant Human IL-15 (rhIL-15) and Mogamulizumab for Patients with Refractory or Relapsed Adult T-Cell Leukemia and Mycosis Fungoides/Sezary Syndrome
Completed Study; data analyses ongoing
18-125 Years
NCI
Soft
20-C-0010
Phase II Trial of Radium-223 in Biochemically Recurrent Prostate Cancer
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
20-C-0006
A National Translational Science Network of Precision-based Immunotherapy for Primary Liver Cancer (PLC)
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
19-I-0108
Elemental Diet for Treatment of Inflammatory Bowel Disease in Patients with Chronic Granulomatous Disease
Enrolling by Invitation
8-65 Years
NIAID
Tissue
19-I-0022
A Prospective, Multicenter Study to Compare and Validate Endoscopic, Histologic, Molecular, and Patient-Reported Outcomes in Pediatric and Adult Patients with Eosinophilic Esophagitis (EoE), Gastritis (EG) and Colitis (EC)
Participants currently recruited/enrolled
3-125 Years
NIAID
Tissue
19-I-0015
Phase 1/2 Randomized, Double-Blind, Placebo-Controlled Study of Safety and Efficacy of Abatacept for Treating Chronic Cytopenia in Cytotoxic T-lymphocyte Antigen 4 (CTLA4) Haploinsufficiency
Participants currently recruited/enrolled
8-65 Years
NIAID
Tissue
19-H-0111
Early Clonal Dynamics During Venetoclax Treatment for Chronic Lymphocytic Leukemia (CLL)
Participants currently recruited/enrolled
18-125 Years
NHLBI
Tissue
19-DK-0072
Non-Alcoholic Fatty Liver Disease, the Hepatic Response to Oral Glucose, and the Effect of Semaglutide (NAFLD HEROES)
Participants currently recruited/enrolled
18-125 Years
NIDDK
Tissue
19-DK-0066
The Evaluation and Management of Endocrine-Related Conditions and Physiology
Participants currently recruited/enrolled
18-90 Years
NIDDK
Tissue
19-CH-0026
Randomized, Double-Blind, Placebo-Controlled Study Plus Open Label Extension with a Double-Blind, Placebo-Controlled, Randomized Withdrawal Period of Diazoxide Choline Extended-Release Tablets (DCCR, Soleno Therapeutics, Inc.) in Participants with Prader
No longer recruiting/follow-up only
4-125 Years
NICHD
Tissue
19-C-0137
A Phase II Study of Ipilimumab, Cabozantinib, and NIvolumab in Rare Genitourinary Cancers (ICONIC)
Participants currently recruited/enrolled
18-125 Years
NCI
Sarcoma
19-C-0134
A Phase 1/1b Study of Enhancement of Immune Reconstitution and Vaccine Responses with Administration of Recombinant Human IL-7-hyFc (NT-I7) in Older Subjects Following Chemotherapy
Participants currently recruited/enrolled
60-125 Years
NCI
Tissue
19-C-0128
A Phase I Study of Mesothelin-Targeted Immunotoxin LMB-100 in Combination with Tofacitinib in Persons with Previously Treated Pancreatic Adenocarcinoma, Cholangiocarcinoma and other Mesothelin Expressing Solid Tumors
Completed Study; data analyses ongoing
18-125 Years
NCI
Tissue
19-C-0117
A Phase 1 / 2 Single Arm Open-label Clinical Trial of Gavocabtagene Autoleucel (gavo-cel) in Patients with Advanced Mesothelin Expressing Cancer
Participants currently recruited/enrolled
18-120 Years
NCI
Tissue
19-C-0104
A Phase II Multi-Institutional Trial to Evaluate Prostate Specific Membrane Antigen (PMSA)-Based PET Imaging of High Risk Prostate Cancer
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
19-C-0096
Studying the Biology of IDH-mutant Gliomas via Longitudinal Observation of 2-Hydroxyglutarate (2-HG) Using MR Spectroscopy
Participants currently recruited/enrolled
18-125 Years
NCI
Soft
19-C-0049
Long Term Follow-up of Mesothelioma Patients and Their Family Members with Germline Mutations in BAP1 and Other Genes
Participants currently recruited/enrolled
2-125 Years
NCI
Tissue
19-C-0025
Tissue Acquisition and Genomics Analysis of Breast Cancer and Other Gynecologic Malignancies
Enrolling by Invitation
18-125 Years
NCI
Tissue
19-C-0023
A Phase II Study of Olaparib (AZD2281) in Patients with Metastatic/Advanced Urothelial Carcinoma and other genitourinary tumors with DNA-Repair Defects
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
18-M-0144
The effects of an ER beta agonist (Lilly Compound LY500307) on estradiol-withdrawal-induced mood symptoms in women with past perimenopausal depression.
Participants currently recruited/enrolled
45-65 Years
NIMH
Tissue
18-I-0041
Investigating the Mechanistic Biology of Primary Immunodeficiency Disorders
Participants currently recruited/enrolled
0-75 Years
NIAID
Tissue
18-I-0022
Use of Ustekinumab (Anti-IL-12/23p40 Monoclonal Antibody) in Patients with Leukocyte Adhesion Deficiency Type 1 (LAD1) who have Inflammatory Pathology
Participants currently recruited/enrolled
12-65 Years
NIAID
Tissue
18-H-0108
Vascular Disease Discovery Protocol
Participants currently recruited/enrolled
2-100 Years
NHLBI
Tissue
18-H-0090
Haplo-identical Transplantation for Severe Aplastic Anemia, Hypo-plastic MDS and PNH using Peripheral Blood Stem Cells and post-transplant Cyclophosphamide for GVHD prophylaxis
Participants currently recruited/enrolled
4-75 Years
NHLBI
Tissue
18-H-0011
Technical Development of Cardiovascular Magnetic Resonance Imaging (CMR) Using a Low Specific Absorption Rate (SAR) Scanner System
Participants currently recruited/enrolled
18-125 Years
NHLBI
Soft
18-DC-0051
Biospecimen Procurement for NIDCD Clinical Protocols
Participants currently recruited/enrolled
0-99 Years
NIDCD
Tissue
18-CH-0120
A Natural History of the Collagen-Related Disorder Osteogenesis Imperfecta and the Genotype-Phenotype Correlation
No longer recruiting/follow-up only
0-125 Years
NICHD
Tissue
18-C-0147
Phase 1 with Expansion Cohorts in a Study of NEO-201 In Adults with Chemo-Resistant Solid Tumors
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
18-C-0138
An Open-Label Phase 2 Study to Evaluate PT2977 for the Treatment of Von Hippel-Lindau Disease-Associated Renal Cell Carcinoma.
No longer recruiting/follow-up only
18-125 Years
NCI
Tissue
18-C-0080
Feasibility and Preliminary Efficacy of an Enhanced Mindfulness Intervention for Children and Young Adults with High Grade or High-Risk Cancer and Their Caregivers: A Pilot Randomized Controlled Trial
Completed Study; data analyses ongoing
5-125 Years
NCI
Sarcoma
18-C-0076
Bicalutamide With or Without Metformin for Biochemical Recurrence in Prostate Cancer Patients (BIMET-1)
Completed Study; data analyses ongoing
18-85 Years
NCI
Tissue
18-C-0062
Phase 2 Trial of XL184 (Cabozantinib) an Oral Small-Molecule Inhibitor of Multiple Kinases, in Children and Young Adults with Refractory Sarcomas, Wilms Tumor, and Other Rare Tumors
Completed Study; data analyses ongoing
2-30 Years
NCI
Sarcoma
18-C-0059
Phase 1 Dose Escalation Study of CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults with Recurrent or Refractory CD19/CD22-expressing B Cell Malignancies
Participants currently recruited/enrolled
3-39 Years
NCI
Tissue
18-C-0058
A Pilot Study to Evaluate the Effects of Castration on the Pharmacokinetics of Zolpidem After Single Dose Administration in Men with Prostate Cancer Undergoing Androgen Deprivation Therapy Compared to Normal Healthy Females
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
18-C-0056
Phase II Trial of M7824 in Subjects with HPV Associated Malignancies
No longer recruiting/follow-up only
18-125 Years
NCI
Tissue
18-C-0038
Long Term Follow-up (LTFU) of Participants Treated with GSK Adoptive Cell Therapies
No longer recruiting/follow-up only
4-125 Years
NCI
Sarcoma
18-C-0028
A Phase I Trial of Highly Conformal, Hypofractionated, Focally Dose Escalated Post-Prostatectomy Radiotherapy
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
18-C-0024
A Single-Arm Phase II Study of Hepatic Artery Infusion Pump Chemotherapy with Floxuridine and Dexamethasone in Combination with Systemic Chemotherapy for Patients with Colorectal Cancer Metastatic to the Liver
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
18-C-0014
Phase I Trial of 5-aza-4'-thio-2'-Deoxycytidine (Aza-TdC) in Patients with Advanced Solid Tumors
Participants currently recruited/enrolled
18-120 Years
NCI
Tissue
18-C-0005
Phase II Trial of Combination Immunotherapy in Biochemically Recurrent Prostate Cancer
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
18-AA-0047
Effects of Sucralose on Drug Absorption and Metabolism (The SweetMeds Study)
Clinical hold/Recruitment or enrollment suspended
18-60 Years
NIAAA
Tissue
17-I-0122
NIAID Centralized Sequencing Protocol
Participants currently recruited/enrolled
0-125 Years
NIAID
Tissue
17-H-0069
Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease
Participants currently recruited/enrolled
2-125 Years
NHLBI
Tissue
17-DK-0054
The Physiological Responses and Adaptation of Brown Adipose Tissue to Chronic Treatment with Beta3-Adrenergic Receptor Agonists
Participants currently recruited/enrolled
18-40 Years
NIDDK
Tissue
17-C-0156
Longitudinal Sample Collection and Tracking for the Developmental Therapeutics Clinic, National Cancer Institute
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
17-C-0153
Phase I Trial of Image Guided Focally Dose Escalated Prostate SBRT for Locally Recurrent Prostate Cancer after Prior Radiotherapy
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
17-C-0149
Phase 2 Trial of Pembrolizumab in Relapsed and Refractory Gray-Zone Lymphoma (GZL), Primary Central Nervous System Lymphoma (PCNSL),and Other Extranodal Diffuse Large B-cell Lymphomas
No longer recruiting/follow-up only
18-125 Years
NCI
Tissue
17-C-0117
A Phase 1/2a, Open-Label, Multicenter Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Anti-Tumor Activity of PEN-866 in Advanced Solid Malignancies
Completed Study; data analyses ongoing
18-125 Years
NCI
Sarcoma
17-C-0109
18F-DCFPyL PET/CT in High Risk and Recurrent Prostate Cancer
Enrolling by Invitation
18-125 Years
NCI
Tissue
17-C-0105
Prospective Study of Clonal Evolution in Follicular Lymphoma
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
17-C-0102
Phase II Trial of the Immune Checkpoint Inhibitor Nivolumab in Patients with Recurrent Select Rare CNS Cancers
Participants currently recruited/enrolled
18-99 Years
NCI
Tissue
17-C-0092
A Phase I/II Study of Pexa-Vec Oncolytic Virus in Combination with Immune Checkpoint Inhibition in Refractory Colorectal Cancer
Completed Study; data analyses ongoing
18-125 Years
NCI
Sarcoma
17-C-0090
DART: Dual Anti-CTLA-4 And Anti-Pd-1 Blockade In Rare Tumors
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
17-C-0086
An Open-label Phase 2 Study to Evaluate PT2385 for the Treatment of Von Hippel-Lindau Disease-Associated Clear Cell Renal Cell Carcinoma
No longer recruiting/follow-up only
18-125 Years
NCI
Tissue
17-C-0070
Phase II Trial of Heated Intraperitoneal Chemotherapy and Gastrectomy for Gastric Cancer with Positive Peritoneal Cytology
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
17-C-0066
A Pilot Study to Investigate the Safety and Clinical Activity of Avelumab (MSB0010718C) in Thymoma and Thymic Carcinoma after Progression on Platinum-Based Chemotherapy
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
17-C-0052
Phase II Evaluation of Nivolumab, an Immune Checkpoint Inhibitor, alone or in combination with Oral Decitabine/Tetrahydrouridine as Second Line Therapy for Non-Small Cell Lung Cancer
Completed Study; data analyses ongoing
18-125 Years
NCI
Tissue
17-C-0044
Prospective Evaluation and Molecular Profiling in Patients with Gastric Tumors
Participants currently recruited/enrolled
2-125 Years
NCI
Tissue
17-C-0043
Hereditary Gastric Cancer Syndromes: An Integrated Genomic and Clinicopathologic Study of the Predisposition to Gastric Cancer
Participants currently recruited/enrolled
2-125 Years
NCI
Tissue
17-C-0034
A Randomized, Double Blind Phase II Trial of Surgery, Radiation Therapy Plus Temozolomide and Pembrolizumab with and without HSPPC-96 in Newly Diagnosed Glioblastoma (GBM)
Completed Study; data analyses ongoing
18-125 Years
NCI
Tissue
17-C-0027
Long-Term Follow up of Patients Undergoing Hematopoietic Stem Cell Transplantation
Participants currently recruited/enrolled
4-125 Years
NCI
Tissue
17-C-0012
A Phase I Study of a Combination of MM-398 and Veliparib in solid tumors
Completed Study; data analyses ongoing
18-125 Years
NCI
Tissue
16-I-0032
High Dose Peripheral Blood Stem Cell Transplantation with Post Transplant Cyclophosphamide for Patients with Chronic Granulomatous Disease
No longer recruiting/follow-up only
4-65 Years
NIAID
Tissue
16-H-0132
CADASIL Disease Discovery
Completed Study; data analyses ongoing
18-100 Years
NHLBI
Soft
16-H-0074
Williams Syndrome (WS) and Supravalvular Aortic Stenosis (SVAS) DNA and Tissue Bank
Participants currently recruited/enrolled
0-85 Years
NHLBI
Tissue
16-H-0063
Williams Syndrome Skin and Vascular Elasticity Study (WS-SAVE Study)
Completed Study; data analyses ongoing
1-70 Years
NHLBI
Tissue
16-EI-0046
Uveitis/Intraocular Inflammatory Disease Biobank (iBank)
No longer recruiting/follow-up only
8-125 Years
NEI
Tissue
16-E-0006
Investigating the Impact of Obesity on Pubertal Development in Girls
Participants currently recruited/enrolled
8-14 Years
NIEHS
Tissue
16-DK-0173
MEASuRE: Metreleptin Effectiveness and Safety Registry
Participants currently recruited/enrolled
0-125 Years
NIDDK
Tissue
16-DK-0125
Evaluation of Adults with Endocrine-Related Conditions
Participants currently recruited/enrolled
18-100 Years
NIDDK
Tissue
16-DK-0068
The Molecular, Cellular, and Genetic Characterization of Human Adipose Tissue and its Role in Metabolism
Participants currently recruited/enrolled
18-125 Years
NIDDK
Tissue
16-DA-N140
Effects of a New Behavioral Intervention on Alcohol Craving and Drinking
Participants currently recruited/enrolled
21-65 Years
NIDA
Soft
16-D-0040
Natural History of Craniofacial Anomalies and Developmental Growth Variants
Participants currently recruited/enrolled
2-125 Years
NIDCR
Tissue
16-CH-0113
Evaluation of Children with Endocrine and Metabolic-Related Conditions
Participants currently recruited/enrolled
0-100 Years
NICHD
Tissue
16-CC-0098
Pilot Study of Ultrasound Guided Focal Thermal Ablation of Prostate Cancer
Clinical hold/Recruitment or enrollment suspended
18-125 Years
CC
Tissue
16-CC-0001
Evaluation of MiSeq for Microbial Identification in Specimens
Enrolling by Invitation
2-125 Years
CC
Tissue
16-C-0151
Evaluation of the Natural History of and Specimen Banking for Patients with Tumors of the Central Nervous System
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
16-C-0128
A Phase I/II Study of Mesothelin-Targeted Immunotoxin LMB-100 Alone or in Combination with Nab-Paclitaxel in Participants with Previously Treated Metastatic and/ or Locally Advanced Pancreatic Ductal Adenocarcinoma and Mesothelin Expressing Solid Tumors
Completed Study; data analyses ongoing
18-125 Years
NCI
Tissue
16-C-0088
A Randomized Phase II/III Study of the Combination of Cediranib and Olaparib Compared to Cediranib or Olaparib Alone, or Standard of Care Chemotherapy in Women with Recurrent Platinum-Resistant or -Refractory Ovarian, Fallopian Tube, or Primary Peritonea
Completed Study; data analyses ongoing
18-125 Years
NCI
Tissue
16-C-0087
Phase I Study of Veliparib (ABT-888), an Oral PARP Inhibitor, and VX-970, an ATR Inhibitor in Combination with Cisplatin in Patients with Refractory Solid Tumors
Completed Study; data analyses ongoing
18-125 Years
NCI
Tissue
16-C-0073
A Phase 2 Study of Olaparib and Cediranib for the Treatment of Recurrent Ovarian Cancer
Completed Study; data analyses ongoing
18-125 Years
NCI
Tissue
16-C-0066
Phase I Study of MK-3475 (Pembrolizumab) in Patients with Human Immunodeficiency Virus (HIV) and Relapsed/Refractory or Disseminated Malignant Neoplasm
Participants currently recruited/enrolled
18-125 Years
NCI
Sarcoma
16-C-0062
A Phase I Study of Subcutaneous Recombinant Human IL-15 (S.C. Rhil-15) and Alemtuzumab for Patients with Refractory or Relapsed Chronic and Acute Adult T-Cell Leukemia (ATL)
Completed Study; data analyses ongoing
18-125 Years
NCI
Tissue
16-C-0061
Biospecimen Procurement for Center for Immuno-Oncology Immunotherapy Protocols
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
16-C-0048
Docetaxel and Prostvac for Metastatic Castration Sensitive Prostate Cancer
No longer recruiting/follow-up only
18-125 Years
NCI
Soft
16-C-0035
Prostvac in Patients with Biochemically Recurrent Prostate Cancer
No longer recruiting/follow-up only
18-125 Years
NCI
Soft
16-C-0010
Care of the Prostate Cancer Patient and Prospective Procurement of Prostate Cancer Tissue
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
16-C-0003
Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies
Participants currently recruited/enrolled
4-75 Years
NCI
Tissue
15-N-0125
Natural History Study of Inflammatory and Infectious Diseases of the Nervous System
Participants currently recruited/enrolled
2-125 Years
NINDS
Tissue
15-M-0109
Checking out Checking In: The Development and Validation of an Electronic Screening Tool for Pediatric Psychosocial Distress
Participants currently recruited/enrolled
8-21 Years
NIMH
Soft
15-H-0190
Human Biospecimen Procurement and Analysis to Support Translational Research to Identify Genetic Etiology and Disease Mechanism(s) in Rare Genetic Vascular/Cardiovascular Diseases
Participants currently recruited/enrolled
0-125 Years
NHLBI
Tissue
15-DK-0119
Thyroid Hormone to Induce Non-Insulin Mediated Glucose Disposal in Patients with Insulin Receptor Mutations
Completed Study; data analyses ongoing
12-65 Years
NIDDK
Tissue
15-DK-0100
A Multidisciplinary Approach to Deciphering the Mechanisms Involved In Microbial Translocation Across the Spectrum of HCV Associated Liver Fibrosis
Completed Study; data analyses ongoing
18-125 Years
NIDDK
Tissue
15-DK-0079
Observational Study of Hepatitis B Virus (HBV) in Patients Coinfected with Human Immunodeficiency Virus (HIV)
Completed Study; data analyses ongoing
18-125 Years
NIDDK
Tissue
15-D-0129
Open-Label, Dose-Escalation Study Evaluating the Safety of a Single Administration of an Adeno-Associated Virus Vector Encoding Human Aquaporin-1 to One Parotid Salivary Gland in Individuals with Irradiation-Induced Parotid Salivary Hypofunction.
Participants currently recruited/enrolled
18-125 Years
NIDCR
Tissue
15-C-0157
Phase I/II Trial of Vandetanib in Combination with Metformin in Subjects with HLRCC or SDH-Associated Kidney Cancer or Sporadic Papillary Renal Cell Carcinoma
Completed Study; data analyses ongoing
18-125 Years
NCI
Soft
15-C-0150
A Phase I/II Trial of Topotecan with VX-970 (M6620), an ATR Kinase Inhibitor in Small Cell Cancers
No longer recruiting/follow-up only
18-125 Years
NCI
Tissue
15-C-0138
Phase I Study of Ipilimumab, Nivolumab, and the Combination in Patients with Newly Diagnosed Glioblastoma
Completed Study; data analyses ongoing
18-125 Years
NCI
Tissue
15-C-0093
Phase I Trial of Turalio(R) (pexidartinib, PLX3397) in Children and Young Adults with Refractory Leukemias and Refractory Solid Tumors Including Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PN)
Participants currently recruited/enrolled
3-35 Years
NCI
Sarcoma
15-C-0087
Care of the Urothelial Cancer Patient and Prospective Collection of Biospecimens from Healthy Volunteers and Urothelial Cancer Patients
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
15-C-0067
A Phase I/II Open Label, Dose Escalation Study of Palifermin (Kepivance) in Persons Undergoing Unrelated Donor Allogeneic Hematopoietic Cell Transplantation
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
15-AG-0063
The Genetic and Epigenetic Signatures of Translational Aging Laboratory Testing (GESTALT)
Participants currently recruited/enrolled
20-125 Years
NIA
Tissue
14-I-0194
Screening of Volunteers for Clinical Trials of Investigational or Licensed Vaccines or Antiviral Products
Participants currently recruited/enrolled
18-65 Years
NIAID
Soft
14-H-0155
A Phase 1/2 Study Evaluating Gene Therapy by Transplantation of Autologous CD34+ Stem Cells Transduced Ex Vivo with the LentiGlobin BB305 Lentiviral Vector in Subjects with Severe Sickle Cell Disease
No longer recruiting/follow-up only
18-50 Years
NHLBI
Tissue
14-H-0127
Characterization of the Pathogenesis of Primary and Secondary Lymphatic Disorders
Participants currently recruited/enrolled
2-90 Years
NHLBI
Tissue
14-H-0077
Nonmyeloablative Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease and Beta-Thalassemia in Individuals with Higher Risk of Transplant Failure
Participants currently recruited/enrolled
4-125 Years
NHLBI
Tissue
14-CH-0028
Evaluation of 68Ga-DOTATATE PET/CT, Octreotide and F-DOPA PET Imaging in Patients with Ectopic Cushing Syndrome
Participants currently recruited/enrolled
18-80 Years
NICHD
Tissue
14-CC-0027
The NIH Exercise Therapy for Advanced Lung Disease Trials: Response and Adaptation to Aerobic Exercise in Patients with Interstitial Lung Disease
Participants currently recruited/enrolled
21-80 Years
CC
Tissue
14-C-0163
Transformation of Plexiform Neurofibromas to Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis Type 1: Clinical, Histopathologic, and Genomic Analysis
Completed Study; data analyses ongoing
10-125 Years
NCI
Tissue
14-C-0105
Tissue Procurement and Natural History Study of Patients with Non-Small Cell Lung Cancer, Small Cell Lung Cancer, Extrapulmonary Small Cell Cancer, Pulmonary Neuroendocrine Tumors, and Thymic Epithelial Tumors
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
14-C-0059
A Phase I Trial of T Cells Expressing an Anti-GD2 Chimeric Antigen Receptor in Children and Young Adults with GD2+ Solid Tumors
Completed Study; data analyses ongoing
1-35 Years
NCI
Sarcoma
14-C-0015
Pilot Trial of BMN 673, an Oral PARP Inhibitor, in Patients With Advanced Solid Tumors and Deleterious BRCA Mutations
Completed Study; data analyses ongoing
18-125 Years
NCI
Tissue
14-C-0007
Phase II Trial of the Gamma-Secretase Inhibitor Nirogacestat (PF-03084014) in Adults with Desmoid Tumors/Aggressive Fibromatosis
No longer recruiting/follow-up only
18-125 Years
NCI
Soft
14-AR-0200
Studies of the Natural History, Pathogenesis, and Outcome of Idiopathic Systemic Vasculitis
Participants currently recruited/enrolled
3-125 Years
NIAMS
Tissue
13-H-0194
Inflammatory Characterization of Known or Possible Cardiovascular Diseases
No longer recruiting/follow-up only
18-125 Years
NHLBI
Tissue
13-H-0065
Human Translational Studies of Inflammation and Cardiometabolic Diseases: The Psoriasis, Atherosclerosis and Cardiometabolic Disease (PACI) Initiative
No longer recruiting/follow-up only
18-125 Years
NHLBI
Tissue
13-H-0051
Bronchodilator Effects of Nebulized versus Inhaled Albuterol in Subjects with Lymphangioleiomyomatosis
Participants currently recruited/enrolled
18-125 Years
NHLBI
Tissue
13-E-0015
Environmental Risk Factors for the Development of Myositis in Military Personnel
No longer recruiting/follow-up only
18-125 Years
NIEHS
Tissue
13-DK-0200
The Mechanism of Human Non-Shivering Thermogenesis and Basal Metabolic Rate
Participants currently recruited/enrolled
18-35 Years
NIDDK
Tissue
13-DK-0091
Combination Therapy of Pegylated Interferon Alfa-2a and Tenofovir DF versus Tenofovir DF Monotherapy in HBeAg-Positive and HBeAg-Negative Chronic Hepatitis B
Completed Study; data analyses ongoing
18-125 Years
NIDDK
Tissue
13-D-0033
Diagnosis and Treatment of Patients in Need of Third Molar Removal and Oral Specimen Acquisition
Participants currently recruited/enrolled
16-50 Years
NIDCR
Tissue
13-CC-0180
Microbiome in Clinical Center Patients
Enrolling by Invitation
2-125 Years
CC
Tissue
13-C-0202
Tissue Procurement and Natural History Study of Patients with Malignant Mesothelioma and Other Mesothelin Expressing Cancers
Participants currently recruited/enrolled
2-125 Years
NCI
Tissue
13-C-0176
Tumor, Normal Tissue and Specimens from Patients Undergoing Evaluation or Surgical Resection of Solid Tumors
Participants currently recruited/enrolled
2-125 Years
NCI
Tissue
13-C-0152
A Phase I Study of Autologous Activated Natural Killer (NK) Cells +/- rhIL15 in Children and Young Adults with Refractory Solid Tumors
Completed Study; data analyses ongoing
2-29 Years
NCI
Sarcoma
13-C-0131
Inpatient Hospice with Procurement of Tissue on Expiration in Thoracic Malignancies, Bladder Cancer, Ovarian Cancer, Epithelial Cancer and Patients Treated with an Adoptive Cellular Therapy
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
13-C-0119
Evaluation of Local Response of Prostate Cancer to Irradiation Using Multiparametric MRI and MR-Guided Biopsies
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
13-C-0105
Molecular Profiling-based Assignment of Cancer Therapy for Patients With Advanced Solid Tumors
Completed Study; data analyses ongoing
18-120 Years
NCI
Tissue
12-EI-0203
Natural History of ABCA4-Related Retinopathies
No longer recruiting/follow-up only
12-125 Years
NEI
Tissue
12-EI-0042
NEI Intramural Biorepository for Retinal Diseases
Participants currently recruited/enrolled
2-125 Years
NEI
Tissue
12-D-0100
Oral Microbial and Immunological Characterization of Patients with Immune Dysfunction
Participants currently recruited/enrolled
7-125 Years
NIDCR
Tissue
12-C-0205
A Phase II Study of Cabozantinib (XL184) in Patients With Advanced/Metastatic Urothelial Carcinoma
Completed Study; data analyses ongoing
18-125 Years
NCI
Tissue
12-C-0197
A Randomized Phase 2 Single-Center Study of Pomalidomide for Chronic GvHD
Completed Study; data analyses ongoing
18-75 Years
NCI
Tissue
12-C-0193
Lymphoid Malignancies and Precursors: Tissue Acquisition Protocol
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
12-C-0178
Longitudinal Assessment and Natural History Study of Children and Adults with MEN2A or MEN2B with or without Medullary Thyroid Carcinoma
Participants currently recruited/enrolled
0-125 Years
NCI
Tissue
12-C-0175
Prospective Procurement of Solid Tumor Tissue to Identify Novel Therapeutic Targets
Completed Study; data analyses ongoing
18-125 Years
NCI
Tissue
12-C-0068
A Randomized Double-Blind Pilot Study of Topical Clobetasol 0.05% Oral rinse for Oral Chronic Graft-Versus-Host Disease
Completed Study; data analyses ongoing
12-125 Years
NCI
Tissue
12-C-0047
A Phase I/II Study of the Safety, Pharmacokinetics and Efficacy of Pomalidomide (CC-4047) in the Treatment of Kaposi Sarcoma in Individuals With or Without HIV
Completed Study; data analyses ongoing
18-125 Years
NCI
Sarcoma
11-N-0210
NIB Repository Protocol
No longer recruiting/follow-up only
5-125 Years
NINDS
Tissue
11-I-0187
The Natural History and Pathogenesis of Human Fungal Infections
Participants currently recruited/enrolled
0-99 Years
NIAID
Tissue
11-I-0109
Viral Infections in Healthy and Immunocompromised Hosts
Participants currently recruited/enrolled
0-125 Years
NIAID
Tissue
11-I-0007
Lentiviral Gene Transfer for Treatment of Children Older Than 2 Years of Age with X-Linked Severe Combined Immunodeficiency
Clinical hold/Recruitment or enrollment suspended
2-40 Years
NIAID
Tissue
11-E-0072
Environmental Risk Factors for the Anti-Synthetase Syndrome
Participants currently recruited/enrolled
2-100 Years
NIEHS
Tissue
11-CC-0152
The Natural History of Liver Disease in a Cohort of Participants with Hepatitis B and/or Hepatitis C with or without HIV Infection
Completed Study; data analyses ongoing
18-99 Years
CC
Tissue
11-C-0255
Clinical, Epidemiologic, and Genetic Studies of Li-Fraumeni Syndrome
Participants currently recruited/enrolled
0-125 Years
NCI
Tissue
11-C-0190
Collection of Tissue Blocks or Slides from Patients with Cancer
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
11-C-0123
A Prospective Randomized Study of Cell Transfer Therapy for Metastatic Melanoma Using Short-Term Cultured Tumor-Infiltrating Lymphocytes Plus IL-2 Following Either a Non-Myeloablative Lymphocyte Depleting Chemotherapy Regimen Alone or in Conjunction with
No longer recruiting/follow-up only
18-66 Years
NCI
Tissue
11-C-0112
Acquisition of Blood and Tumor Tissue Samples from Patients with Gastrointestinal Cancer
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
11-C-0096
Pilot Trial of Molecular Profiling and Targeted Therapy for Advanced Non-Small Cell Lung Cancer, Small Cell Lung Cancer, and Thymic Malignancies
No longer recruiting/follow-up only
18-125 Years
NCI
Tissue
11-C-0034
DICER1-Related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History Study
Participants currently recruited/enrolled
0-125 Years
NCI
Tissue
11-AR-0223
Studies on the Natural History and Pathogenesis of Spondyloarthritis
Participants currently recruited/enrolled
2-125 Years
NIAMS
Tissue
10-I-0216
Studies of Disorders with Increased Susceptibility to Fungal Infections
Participants currently recruited/enrolled
0-125 Years
NIAID
Tissue
10-I-0195
Natural History of Tuberculosis
Participants currently recruited/enrolled
2-125 Years
NIAID
Tissue
10-I-0109
VRC 900: Evaluation of Tissue-Specific Immune Responses in Adults 18 Years of Age and Older
Participants currently recruited/enrolled
18-125 Years
NIAID
Tissue
10-HG-0065
Whole Genome Medical Sequencing for Gene Discovery
Participants currently recruited/enrolled
0-125 Years
NHGRI
Tissue
10-H-0126
Cardiovascular Disease Discovery Protocol
Participants currently recruited/enrolled
1-100 Years
NHLBI
Tissue
10-DK-0102
Clinical and Genetic Studies in Familial Non-Medullary Thyroid Cancer
Participants currently recruited/enrolled
7-125 Years
NIDDK
Tissue
10-CC-0217
A Comparison of Methods for Assisting Needle Angle Selection During Image-Guided Tissue Biopsy
Completed Study; data analyses ongoing
18-125 Years
CC
Tissue
10-CC-0053
Collection of Bone Marrow from Healthy Volunteers and Patients for the Production of Clinical Bone Marrow Stromal Cell (BMSC) Products
Completed Study; data analyses ongoing
18-125 Years
CC
Tissue
10-C-0066
A Study of Hairy Cell and other Leukemias with a Focus on Recombinant Immunotoxins for Cancer Treatment
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
09-I-0184
Studies in the Pathogenesis of Systemic Capillary Leak Syndrome
Participants currently recruited/enrolled
0-125 Years
NIAID
Tissue
09-I-0133
Establishing Fibroblast-derived Cell Lines from Skin/Tissue Biopsies of Patients with Immunodeficiency or Immunodysregulation Disorders
Enrolling by Invitation
2-85 Years
NIAID
Tissue
09-I-0032
Comprehensive Multimodal Analysis of Patients with Neuroimmunological Diseases of the CNS
Participants currently recruited/enrolled
0-99 Years
NIAID
Tissue
09-H-0225
Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Severe Congenital Anemias Including Sickle Cell Disease and Beta-Thalassemia
No longer recruiting/follow-up only
2-125 Years
NHLBI
Tissue
09-DK-0097
Vitamin E Pharmacokinetics and Biomarkers in Normal and Obese Women
Completed Study; data analyses ongoing
18-55 Years
NIDDK
Tissue
09-C-0242
Prospective Comprehensive Molecular Analysis of Endocrine Neoplasms
Participants currently recruited/enrolled
4-125 Years
NCI
Tissue
08-H-0046
Co-Infusion of Umbilical Cord Blood and Haploidentical CD34+ Cells Following Nonmyeloablative Conditioning as Treatment for Severe Aplastic Anemia and MDS Associated with Severe Neutropenia Refractory to Immunosuppressive Therapy
Completed Study; data analyses ongoing
4-75 Years
NHLBI
Tissue
08-C-0130
A Phase II Trial of Peginterferon alfa-2b (PEG-Intron) for Neurofibromatosis Type 1 Related Unresectable, Symptomatic or Life-Threatening Plexiform Neurofibromas
Completed Study; data analyses ongoing
0-21 Years
NCI
Tissue
07-N-0190
Neurobiological Studies of Functional Movement Disorders and Non-Epileptic Seizures
No longer recruiting/follow-up only
18-125 Years
NINDS
Tissue
07-I-0183
The Collection of Research Samples and/or Data for Repository from Related or Unrelated Hematopoietic Stem Cell Transplantation Recipients for the National Marrow Donor Program
Participants currently recruited/enrolled
2-125 Years
NIAID
Tissue
07-I-0033
Screening Protocol for Detection and Characterization of Infections and Infection Susceptibility
Participants currently recruited/enrolled
0-125 Years
NIAID
Tissue
07-H-0142
Research Respiratory Tract Procedures
Participants currently recruited/enrolled
10-125 Years
NHLBI
Tissue
07-H-0113
Procurement and Analysis of Blood, Bone Marrow, and Buccal Mucosa Samples from Healthy Volunteers to Support Clinical and Translational Research Projects in the NHLBI
Participants currently recruited/enrolled
8-125 Years
NHLBI
Tissue
07-H-0005
Pilot Study of Topical Dexamethasone 0.01% Solution for Prevention of Oral Chronic Graft Versus Host Disease
Completed Study; data analyses ongoing
12-110 Years
NHLBI
Tissue
07-E-0012
Rituximab in the Treatment of Refractory Adult and Juvenile Dermatomyositis (DM) and Adult Polymyositis (PM)
Completed Study; data analyses ongoing
2-125 Years
NIEHS
Tissue
07-DK-0077
Study of the Phenotype of Overweight and Obese Adults
Participants currently recruited/enrolled
18-100 Years
NIDDK
Tissue
07-C-0195
Phase II Trial of Targeted Immune-Depleting Chemotherapy and Reduced-Intensity Allogeneic Hematopoietic Stem Cell Transplantation Using 8/8 and 7/8 HLA-matched Unrelated Donors and Utilizing Two Graft-versus-Host Disease Prophylaxis Regimens for the Trea
Completed Study; data analyses ongoing
18-74 Years
NCI
Tissue
06-I-0153
A Pilot Study of Hepatic Fibrosis in HIV/AIDS Patients with Chronically Elevated Transaminases on Antiretroviral Therapy
No longer recruiting/follow-up only
18-100 Years
NIAID
Tissue
06-I-0015
Screening Protocol for Genetic Diseases of Lymphocyte Homeostasis and Programmed Cell Death
Participants currently recruited/enrolled
0-125 Years
NIAID
Tissue
06-H-0217
Genetic Disorders of Mucociliary Clearance
Completed Study; data analyses ongoing
2-65 Years
NHLBI
Soft
06-H-0072
Atorvastatin as a Disease Modifying Agent in Stage II and III Pulmonary Sarcoidosis: A Randomized, Double-Blind, Placebo-Controlled Trial
Completed Study; data analyses ongoing
18-70 Years
NHLBI
Tissue
06-EI-0236
National Ophthalmic Genotyping and Phenotyping Network Stage 1 - Creation of DNA Repository for Inherited Ophthalmic Diseases
No longer recruiting/follow-up only
2-125 Years
NEI
Tissue
06-C-0219
An Exploratory Study of Biologic and Pathophysiologic Effects of Radiation Therapy in Pediatric Patients with Central Nervous System Tumors
Completed Study; data analyses ongoing
0-21 Years
NCI
Tissue
06-C-0213
Tissue Procurement Protocol for the Developmental Therapeutics Clinic, National Cancer Institute (NCI)
Participants currently recruited/enrolled
0-125 Years
NCI
Tissue
06-C-0014
Prospective Evaluation of Genetic and Epigenetic Alterations in Patients with Thoracic Malignancies
Participants currently recruited/enrolled
2-125 Years
NCI
Tissue
06-AR-0198
A Pilot Pediatric/Adult Study of Gene Expression Profiling and Clinical Characterization of Phototoxicity
Completed Study; data analyses ongoing
8-100 Years
NIAMS
Tissue
05-I-0213
Screening and Baseline Assessment of Patients with Abnormalities of Immune Function
Participants currently recruited/enrolled
0-125 Years
NIAID
Tissue
05-H-0130
Long-Term Evaluation and Follow Up Care of Patients Treated with Allogeneic Stem Cell Transplants
Participants currently recruited/enrolled
7-80 Years
NHLBI
Tissue
05-CH-0013
Adrenal Function in Critical Illness
Completed Study; data analyses ongoing
15-80 Years
NICHD
Tissue
05-CC-0091
Electromagnetic Tracking of Devices During Interventional Procedures
Enrolling by Invitation
18-125 Years
CC
Tissue
05-C-0252
Phase III Randomized Study of R-CHOP v. Dose-Adjusted EPOCH-R with Molecular Profiling in Untreated de Novo Diffuse Large B-Cell Lymphomas
Completed Study; data analyses ongoing
18-125 Years
NCI
Tissue
05-C-0152
Variation in Gene Expression in Neurofibromatosis Type 1
Completed Study; data analyses ongoing
2-100 Years
NCI
Tissue
04-N-0056
The Neural Immune Mechanisms and Genetic Influences on Chronic Pelvic Pain in Women with Endometriosis
Completed Study; data analyses ongoing
18-50 Years
NINDS
Tissue
04-I-0286
A Longitudinal Study of Familial Hypereosinophilia (FE): Natural History and Markers of Disease Progression
Participants currently recruited/enrolled
1-100 Years
NIAID
Tissue
04-HG-0127
Clinical and Basic Investigations of Methylmalonic Acidemia (MMA) and Related Disorders
Participants currently recruited/enrolled
0-125 Years
NHGRI
Tissue
04-H-0012
Collection of Blood, Bone Marrow, Urine, and/or Tissue Samples from Patients with Solid Tumors, Hematological Malignancies or Non-Malignant Hematologic Disorders or HLA Compatible Family Members
Participants currently recruited/enrolled
2-125 Years
NHLBI
Tissue
04-DK-0021
Urinary Vitamin C Loss in Subjects with and without Diabetes
Participants currently recruited/enrolled
18-65 Years
NIDDK
Tissue
04-CH-0077
Investigations of Bone-Related Connective Tissue Disorders
Completed Study; data analyses ongoing
0-70 Years
NICHD
Tissue
04-C-0281
Natural History Study of Clinical and Biological Factors Determining Outcomes in Chronic Graft-Versus-Host Disease
Participants currently recruited/enrolled
1-125 Years
NCI
Tissue
04-C-0275
Targeted Oncolytic Virotherapy and Natural History Study of KSHV-Associated Multicentric Castleman's Disease with Laboratory and Clinical Correlates of Disease Activity
No longer recruiting/follow-up only
18-125 Years
NCI
Sarcoma
04-C-0238
A Phase 2 Study of 17-Allylamino-17-Demethoxygeldanamycin in Patients with Von Hippel Lindau Disease and Renal Tumors
Completed Study; data analyses ongoing
18-125 Years
NCI
Tissue
04-C-0232
A Multi-Institutional Study of Proteomic Evaluation of Epithelial Ovarian Cancer, Primary Peritoneal Cancer, and Fallopian Tube Cancer Patients in First Clinical Remission: Development of a Protein Fingerprint Profile of Relapse
Completed Study; data analyses ongoing
18-125 Years
NCI
Tissue
04-AR-0205
Progression of Spinal Fusion in Ankylosing Spondylitis
Completed Study; data analyses ongoing
18-125 Years
NIAMS
Tissue
03-N-0164
Evaluation and Treatment of Neurosurgical Disorders
Participants currently recruited/enrolled
4-125 Years
NINDS
Tissue
03-H-0280
Disease Pathogenesis and Natural History of Lipid Disorders
Participants currently recruited/enrolled
2-100 Years
NHLBI
Tissue
03-EI-0033
X-Linked Juvenile Retinoschisis - Clinical and Molecular Studies
Participants currently recruited/enrolled
0-125 Years
NEI
Tissue
03-E-0099
Pathogenic Studies In Families With Twins Or Siblings Discordant For Systemic Rheumatic Disorders
Completed Study; data analyses ongoing
2-125 Years
NIEHS
Tissue
03-C-0278
A Comparative Study of Pediatric CNS Tumor Activity as Assessed by 18F-FDG PET Imaging and Proton Magnetic Resonance Spectroscopic Imaging (1H-MRSI)
Completed Study; data analyses ongoing
1-21 Years
NCI
Tissue
03-C-0277
Cell Harvest and Preparation for Surgery Branch Adoptive Cell Therapy Protocols
Enrolling by Invitation
18-125 Years
NCI
Tissue
03-C-0066
Hereditary Leiomyomatosis Renal Cell Cancer (HLRCC): Identification of the Disease Gene, and Characterization of the Predisposition to Renal Cancer
Participants currently recruited/enrolled
2-125 Years
NCI
Tissue
03-AG-0325
The Baltimore Longitudinal Study of Aging(BLSA)
Participants currently recruited/enrolled
20-125 Years
NIA
Tissue
02-N-0014
Research Study of Specimens Obtained During Epilepsy Surgery
Completed Study; data analyses ongoing
4-125 Years
NINDS
Tissue
02-I-0286
Efficacy of Tyrosine Kinase Inhibition in Reducing Eosinophilia in Patients with Myeloid and/or Steroid-Refractory Hypereosinophilic Syndrome
Participants currently recruited/enrolled
2-125 Years
NIAID
Tissue
02-I-0147
Genetic Studies of Chronic Active Epstein-Barr Virus Infection
Participants currently recruited/enrolled
1-125 Years
NIAID
Tissue
02-I-0055
Evaluation, Treatment, and Follow-up of Patients with Lyme Disease
Participants currently recruited/enrolled
2-125 Years
NIAID
Tissue
02-H-0250
A Phase I/II Study of HLA-matched Mobilized Peripheral Blood Hematopoietic Stem Cell Transplantation for Advanced Mycosis Fungoides/Sezary Syndrome Using Nonmyeloablative Conditioning with Campath-1H
Completed Study; data analyses ongoing
18-125 Years
NHLBI
Tissue
02-DK-0022
Long-Term Efficacy of Leptin Replacement in Treatment of Lipodystrophy
Completed Study; data analyses ongoing
1-125 Years
NIDDK
Tissue
02-CH-0311
Investigations into Inborn Errors of Cholesterol Synthesis and Related Disorders
Participants currently recruited/enrolled
0-125 Years
NICHD
Tissue
02-C-0268
Prospective Study of Prophylactic Salpingo-Oophorectomy and Longitudinal CA-125 Screening Among Women at Increased Genetic Risk of Ovarian Cancer
Completed Study; data analyses ongoing
19-100 Years
NCI
Tissue
02-C-0212
Clinical, Genetic, Behavioral, Laboratory and Epidemiologic Characterization of Individuals and Families at High Risk of Breast/Ovarian Cancer
Completed Study; data analyses ongoing
18-100 Years
NCI
Tissue
02-C-0159
Birt-Hogg-Dub(SqrRoot)(Copyright) Syndrome: Characterization of the FLCN Disease Gene and Predisposition to Renal Cancer, Cutaneous Fibrofolliculoma and Pulmonary Cysts
Participants currently recruited/enrolled
2-125 Years
NCI
Tissue
02-C-0052
Etiologic Investigation of Cancer Susceptibility in Inherited Bone Marrow Failure Syndromes: A Natural History Study
Participants currently recruited/enrolled
0-125 Years
NCI
Tissue
01-N-0007
Evaluation, Pathogenesis, and Treatment of Patients with or at Risk for Cerebrovascular Disease (A Natural History/Disease Pathogenesis Protocol)
Participants currently recruited/enrolled
18-125 Years
NINDS
Tissue
01-I-0238
Host Response to Infection and Treatment in Leishmania Infection of Humans
Participants currently recruited/enrolled
3-100 Years
NIAID
Tissue
01-I-0202
Natural History, Genetics, Phenotype, and Treatment of Mycobacterial Infections
Participants currently recruited/enrolled
0-100 Years
NIAID
Tissue
01-HG-0109
Natural History Study of the Clinical and Molecular Manifestations of Smith-Magenis Syndrome (SMS)
No longer recruiting/follow-up only
0-125 Years
NHGRI
Tissue
01-H-0122
Collection and Storage of Umbilical Cord Hematopoietic Stem Cells for Sickle Cell Disease Therapy
Participants currently recruited/enrolled
18-45 Years
NHLBI
Tissue
01-DC-0229
Genetic Analysis of Hereditary Disorders of Hearing and Balance
Completed Study; data analyses ongoing
0-99 Years
NIDCD
Tissue
01-DC-0228
Clinical and Molecular Analysis of Enlarged Vestibular Aqueducts
Completed Study; data analyses ongoing
0-99 Years
NIDCD
Tissue
01-D-0184
A Natural History Study of Bone and Mineral Disorders
Participants currently recruited/enrolled
0-125 Years
NIDCR
Tissue
01-CC-0231
A Prospective Study of Transfusion-Transmitted Infections
Completed Study; data analyses ongoing
0-125 Years
CC
Sarcoma
01-CC-0045
Studies of Phlebotomy Therapy in Hereditary Hemochromatosis
Participants currently recruited/enrolled
18-125 Years
CC
Tissue
01-C-0129
Eligibility Screening for the NIH Intramural Research Program Clinical Protocols
Enrolling by Invitation
0-125 Years
NCI
Sarcoma
01-C-0009
Breast Imaging Screening Studies in Women at High Genetic Risk of Breast Cancer: Annual Follow-up Study
Completed Study; data analyses ongoing
18-100 Years
NCI
Tissue
00-I-0159
Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection Syndrome (HIES)
Participants currently recruited/enrolled
0-125 Years
NIAID
Tissue
00-HG-0209
Molecular and Clinical Studies of Primary Immunodeficiency Diseases
No longer recruiting/follow-up only
3-125 Years
NHGRI
Tissue
00-HG-0141
Clinical, Biochemical, and Molecular Investigations into Alkaptonuria
Participants currently recruited/enrolled
2-125 Years
NHGRI
Tissue
00-H-0051
Cutaneous Tumorigenesis in Patients with Tuberous Sclerosis
Participants currently recruited/enrolled
18-90 Years
NHLBI
Tissue
00-CH-0160
Clinical and Molecular Analysis of ACTH-Independent Steroid Hormone Production in Adrenocortical Tissue
Completed Study; data analyses ongoing
3-70 Years
NICHD
Tissue
00-CH-0136
A Trial of Pamidronate in Children with Osteogenesis Imperfecta
Completed Study; data analyses ongoing
2-17 Years
NICHD
Tissue
00-C-0078
Collection of Blood, Fluid, Bone Marrow, Tumor, or Tissue Samples from Patients with Cancer or Normal Volunteers
Participants currently recruited/enrolled
18-125 Years
NCI
Tissue
99-C-0099
Examination of Clinical and Laboratory Abnormalities in Patients with Defective DNA Repair: Xeroderma Pigmentosum, Cockayne Syndrome, or Trichothiodystrophy
Participants currently recruited/enrolled
0-125 Years
NCI
Tissue
98-D-0145
Screening and Natural History of Patients with Polyostotic Fibrous Dysplasia and the McCune-Albright Syndrome
Participants currently recruited/enrolled
0-100 Years
NIDCR
Tissue
97-I-0096
Evaluation, Treatment, and Monitoring of Patients With Known or Suspected Parasitic Infection
Participants currently recruited/enrolled
3-125 Years
NIAID
Tissue
97-HG-0192
Genetic Studies in the Amish and Mennonites
Completed Study; data analyses ongoing
18-125 Years
NHGRI
Tissue
97-CH-0076
A Clinical and Genetic Investigation of Pituitary and HYPOTHALAMIC Tumors and Related Disorders
Participants currently recruited/enrolled
3-70 Years
NICHD
Tissue
97-CH-0064
Evaluation and Intervention for Ambulation, Growth, and Basilar Invagination in Osteogenesis Imperfecta
Completed Study; data analyses ongoing
0-10 Years
NICHD
Tissue
97-C-0147
Collection of Serum and Tissue Samples from Patients with Biopsy-Proved or Suspected Malignant Diseases
Participants currently recruited/enrolled
2-125 Years
NCI
Tissue
96-H-0049
Use of Granulocyte Colony Stimulating Factor (G-CSF) Mobilized Leukapheresis Collections from Healthy Volunteers to Develop Improved Methods of Stem Cell and Lymphocyte Selection for Allogeneic Transplantation
Participants currently recruited/enrolled
18-60 Years
NHLBI
Tissue
95-I-0066
Genetic Analysis of Immune Disorders
Participants currently recruited/enrolled
0-125 Years
NIAID
Tissue
95-I-0027
Virologic and Immunologic Evaluation of Lymph Node, Tonsillar and Intestinal Biopsies, and Bronchoalveolar Lavage Fluid
Participants currently recruited/enrolled
18-125 Years
NIAID
Tissue
94-HG-0132
The Phenotype and Etiology of Proteus Syndrome
Participants currently recruited/enrolled
0-125 Years
NHGRI
Tissue
94-E-0165
Studies in the Natural History and Pathogenesis of Childhood-Onset and Adult-Onset Idiopathic Inflammatory Myopathies
Participants currently recruited/enrolled
2-100 Years
NIEHS
Tissue
94-DK-0127
Pathogenesis of Glomerulosclerosis
Completed Study; data analyses ongoing
2-125 Years
NIDDK
Tissue
94-AR-0066
Studies of the Pathogenesis and Natural History of Systemic Lupus Erythematosus (SLE)
Participants currently recruited/enrolled
9-125 Years
NIAMS
Tissue
93-I-0119
Detection and Characterization of Host Defense Defects
Participants currently recruited/enrolled
0-125 Years
NIAID
Tissue
93-I-0086
Evaluation and Long-Term Follow-Up of Patients with Acute or Chronic Inflammatory Disorders
Enrolling by Invitation
2-125 Years
NIAID
Tissue
93-I-0063
Study of the Immunopathogenesis, Natural History, and Genetics of Autoimmune Lymphoproliferative Syndrome (ALPS) Associated with an Expansion of CD4-8-/TCR alpha/beta+ T Cells
Participants currently recruited/enrolled
0-99 Years
NIAID
Tissue
92-I-0125
A Study of Viral Burden in Peripheral Blood Versus Lymphoid and Bone Marrow Tissue in HIV-Infected Individuals
Participants currently recruited/enrolled
18-125 Years
NIAID
Tissue
92-DK-0156
Studies of Immunologically-Mediated Kidney Diseases
Participants currently recruited/enrolled
10-125 Years
NIDDK
Tissue
91-I-0140
Studies of the Pathogenesis of HIV Infection in Human Peripheral Blood Cells and/or Body Fluids in HIV-Infected and HIV-Uninfected Volunteers
Participants currently recruited/enrolled
18-125 Years
NIAID
Tissue
91-AR-0196
Studies on the Natural History and Pathogenesis of Polymyositis, Dermatomyositis, and Related Diseases
Participants currently recruited/enrolled
16-125 Years
NIAMS
Tissue
90-DK-0137
Evaluation of the Gastrinoma in Patients with Zollinger-Ellison Syndrome
Completed Study; data analyses ongoing
18-100 Years
NIDDK
Tissue
90-CC-0168
A Rigid Body Database on Human Movement
Participants currently recruited/enrolled
0-125 Years
CC
Soft
89-I-0158
Studies of Immune Regulation in Patients with Common Variable Immunodeficiency and Related Humoral Immunodeficiency Syndromes
Participants currently recruited/enrolled
2-125 Years
NIAID
Tissue
88-I-0172
A Phase III Study with Long-Term Follow-Up of Zidovudine Versus Zidovudine and Alpha-Interferon Versus Alpha-Interferon in Patients with Early HIV Infection
No longer recruiting/follow-up only
18-125 Years
NIAID
Sarcoma
82-I-0183
A Natural History Study of the Immune Regulation of Idiopathic Inflammatory Bowel Diseases: Crohn's Disease, Ulcerative Colitis, and Other Inflammatory Conditions of the Gut
Participants currently recruited/enrolled
0-75 Years
NIAID
Tissue
78-HG-0093
Use of Cysteamine in the Treatment of Cystinosis
Participants currently recruited/enrolled
0-125 Years
NHGRI
Tissue
77-DK-0096
Studies on Thyroid Nodules and Thyroid Cancer
Participants currently recruited/enrolled
0-125 Years
NIDDK
Tissue
77-DK-0002
Evaluation of Patients with Thyroid Function Disorders
Participants currently recruited/enrolled
0-125 Years
NIDDK
Tissue