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160 Studies found from all possible combinations of your search terms. Select a protocol that you wish to review.
Protocol Number Title Protocol Status Min-Max Age Institute Keywords
21-N-0016Phase I/II Study of Teriflunomide in HTLV-1 Associated Myelopathy/Tropical Spastic ParaparesisParticipants currently recruited/enrolled18-125 YearsNINDSProgressive Multiple Sclerosis
17-I-0083Targeting Residual Activity By Precision, Biomarker-Guided Combination Therapies of Multiple Sclerosis (TRAP-MS)Participants currently recruited/enrolled18-125 YearsNIAIDProgressive Multiple Sclerosis
13-N-0017Natural History Study of Progressive Multifocal Leukoencephalopathy (PML)Participants currently recruited/enrolled2-125 YearsNINDSProgressive Multiple Sclerosis
001124-IExpanded Access IND Protocol: Use of Tecovirimat (TPOXX (R)) for Treatment of Human Non-Variola Orthopoxvirus Infections in Adults and ChildrenEnrolling by Invitation0-125 YearsNIAIDSecondary Progressive
000748-DKAnalysis of the Utility of Polygenic Scores for Prediction of Incident Type 2 Diabetes Across Multiple Ancestry GroupsNo longer recruiting/follow-up only0-125 YearsNIDDKSecondary Multiple
000483-MPET Imaging of Cyclooxygenases in Multiple SclerosisParticipants currently recruited/enrolled18-99 YearsNIMH Multiple Sclerosis
21-N-0010A Phase 2 Clinical Trial of Tolebrutinib, a Brain-penetrant Bruton's Tyrosine Kinase Inhibitor, for the Modulation of Chronically Inflamed White Matter Lesions in Multiple SclerosisNo longer recruiting/follow-up only18-125 YearsNINDSMultiple Sclerosis
20-N-0064An observational study to assess clinical manifestations and biomarkers in amyotrophic lateral sclerosis type 4 and other inherited neurological disorders of RNA processing.Participants currently recruited/enrolled5-125 YearsNINDSProgressive Sclerosis
20-C-0062A phase 1b Study of Nivolumab in Patients with Autoimmune Disorders and Advanced Malignancies (AIM-NIVO)Participants currently recruited/enrolled18-125 YearsNCI Multiple Sclerosis
19-N-0124Anakinra for the Treatment of Chronically Inflamed White Matter Lesions in Multiple SclerosisParticipants currently recruited/enrolled18-120 YearsNINDSMultiple Sclerosis
19-N-0081A Traveling Subject Study of Replicability in Conventional and Advanced MRI MS BiomarkersCompleted Study; data analyses ongoing18-125 YearsNINDSMultiple Sclerosis
17-N-0131Investigating Complex Neurodegenerative Disorders Related to Amyotrophic Lateral Sclerosis and Frontotemporal DementiaParticipants currently recruited/enrolled18-125 YearsNINDSProgressive Sclerosis
16-N-0114The Effect of Corticosteroids on Inflammation at the Edge of Acute Multiple Sclerosis Plaques: An Investigator-Blinded StudyParticipants currently recruited/enrolled18-125 YearsNINDSMultiple Sclerosis
16-N-0055The Pathological Basis of MRI Signal Changes in Multiple Sclerosis: A Longitudinal In Vivo-to-Postmortem StudyParticipants currently recruited/enrolled18-125 YearsNINDSMultiple Sclerosis
15-N-0156In Vivo Characterization of Inflammation with Ferumoxytol, an Ultrasmall Superparamagnetic Iron Oxide Nanoparticle, on 7 Tesla Magnetic Resonance ImagingCompleted Study; data analyses ongoing18-70 YearsNINDSMultiple Sclerosis
12-N-0122Integrating Genetic and Environmental Risk Scores into an Algorithm to Predict Multiple Sclerosis SusceptibilityCompleted Study; data analyses ongoing18-125 YearsNINDSMultiple Sclerosis
11-N-0210NIB Repository ProtocolNo longer recruiting/follow-up only5-125 YearsNINDSMultiple Sclerosis
11-M-0251A Longitudinal Investigation of the Endocrine and Neurobiologic Events Accompanying PubertyParticipants currently recruited/enrolled7-35 YearsNIMH Progressive Multiple
09-I-0032Comprehensive Multimodal Analysis of Patients with Neuroimmunological Diseases of the CNSParticipants currently recruited/enrolled0-99 YearsNIAIDMultiple Sclerosis
05-CC-0041Endothelial Cell Dysfunction in Pulmonary Arterial Hypertension: Biomarkers, Mechanisms of Disease and Novel Therapeutic TargetsCompleted Study; data analyses ongoing18-125 YearsCC Secondary Multiple
00-H-0051Cutaneous Tumorigenesis in Patients with Tuberous SclerosisParticipants currently recruited/enrolled18-90 YearsNHLBIMultiple Sclerosis
98-D-0145Screening and Natural History of Patients with Polyostotic Fibrous Dysplasia and the McCune-Albright SyndromeParticipants currently recruited/enrolled0-100 YearsNIDCRSecondary Multiple
97-CH-0064Evaluation and Intervention for Ambulation, Growth, and Basilar Invagination in Osteogenesis ImperfectaCompleted Study; data analyses ongoing0-10 YearsNICHDSecondary Multiple
96-I-0052A Comprehensive Clinical, Microbiological and Immunological Assessment of Patients with Suspected Post Treatment Lyme Disease Syndrome and Selected Control PopulationsParticipants currently recruited/enrolled13-125 YearsNIAIDMultiple Sclerosis
94-HG-0132The Phenotype and Etiology of Proteus SyndromeParticipants currently recruited/enrolled0-125 YearsNHGRIProgressive Multiple
89-N-0045Evaluation of Progression in Multiple Sclerosis by Magnetic Resonance Imaging (MRI)Participants currently recruited/enrolled18-125 YearsNINDSMultiple Sclerosis
001078-IPhase 1 Trial to Model Primary, Secondary, and Tertiary Dengue Using a Monovalent VaccineParticipants currently recruited/enrolled18-59 YearsNIAIDSecondary
001058-DKA Phase 1b/2a Open-label Multiple-ascending Dose Exploratory Study of CRN04894 in ACTH-dependent Cushing's Syndrome (Cushing's Disease or Ectopic ACTH Syndrome)Recruitment has not started18-75 YearsNIDDKMultiple
001018-CHEstablishment of Genomic and Phenotypic Database for Niemann-Pick Disease, Type CParticipants currently recruited/enrolled0-125 YearsNICHDProgressive
000923-HObservational Study of Cardiac Arrhythmias in Subjects Treated with BTK InhibitorsParticipants currently recruited/enrolled18-110 YearsNHLBIMultiple
000908-DKPeripheral Blood and Urine Immune Cell Phenotyping in Membranous Nephropathy using FACS and Single Cell RNA-seqParticipants currently recruited/enrolled18-125 YearsNIDDKSecondary
000686-CHIntrathecal 2-Hydroxypropyl-Beta-Cyclodextrin for Neurological Decline in Patients with Niemann-Pick Disease Type C1Participants currently recruited/enrolled18-125 YearsNICHDProgressive
000647-CAn Open-label, Multicenter Follow-up Study to Collect Long-term Data on Participants from Multiple Bintrafusp alfa (M7824) Clinical StudiesRecruitment has not started18-125 YearsNCI Multiple
000643-CPhase I/II Study of Pacritinib, A JAK2/IRAK1/CSF1R Inhibitor, in Refractory Chronic Graft-Versus-Host Disease (cGVHD) After Allogeneic Hematopoietic Stem Cell Transplantation (HSCT)Participants currently recruited/enrolled18-125 YearsNCI Multiple
000527-MCNS Correlates of Extended Sleep RestrictionParticipants currently recruited/enrolled18-39 YearsNIMH Multiple
000516-CPhase 1 Study of Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (VIPOR) for Diffuse Large B-cell Lymphoma involving the Central Nervous SystemParticipants currently recruited/enrolled18-125 YearsNCI Secondary
000489-CPhase I/II Study Using Prophylactic Donor Lymphocyte Infusion Early Post-Transplant After Allogeneic Hematopoietic Cell Transplantation Using Post-Transplantation Cyclophosphamide for High-Risk Hematologic MalignanciesClinical hold/Recruitment or enrollment suspended12-125 YearsNCI Multiple
000428-NAn Observational Study to Assess Clinical, Molecular and Imaging Biomarkers in Spinal and Bulbar Muscular Atrophy (SBMA)Participants currently recruited/enrolled18-125 YearsNINDSProgressive
000413-HNatural History study of CADASILParticipants currently recruited/enrolled18-100 YearsNHLBIProgressive
000393-DKDiabetic Kidney Disease and Related Complications in American Indians with Type 2 DiabetesParticipants currently recruited/enrolled18-125 YearsNIDDKSecondary
000344-DKNatural History Study of Parathyroid DisordersParticipants currently recruited/enrolled0-125 YearsNIDDKMultiple
000178-CHyperspectral Analysis of Sweat Metabolite Biometrics for Real-Time Detection of COVID-19Participants currently recruited/enrolled18-125 YearsNCI Multiple
000137-CHImplications of Maternal 45,X Mosaicism As A Secondary Genomic Finding Following Cell-free DNA Sequencing During Pregnancy: A Deep Phenotype StudyRecruitment has not started18-99 YearsNICHDSecondary
000126-NA Pilot Study of NT-I7, a Long-Acting Recombinant IL-7 Molecule, as an Immune Reconstitution Strategy for Lymphopenia in Patients with Progressive Multifocal LeukoencephalopathyParticipants currently recruited/enrolled18-125 YearsNINDSProgressive
000115-CA Trial of the Safety and Immunogenicity of the COVID-19 Vaccine (mRNA-1273) in Participants with Hematologic Malignancies and Various Regimens of Immunosuppression, and in Participants with Solid Tumors on PD1/PDL1 Inhibitor Therapy, Including Booster DParticipants currently recruited/enrolled18-125 YearsNCI Multiple
000108-EIAn Observational Prospective Natural History Study of Stargardt-like Macular Dystrophy (STDG3) Secondary to Mutations in ELOVL4Participants currently recruited/enrolled10-125 YearsNEI Secondary
000071-AARepository of Research Data and Samples, National Institute on Alcohol Abuse and AlcoholismParticipants currently recruited/enrolled18-125 YearsNIAAASecondary
000049-HEvaluation of the Safety,Tolerability, Pharmacokinetics, and Pharmacodynamics of Long-term Mitapivat Dosing in Subjects with Stable Sickle Cell Disease: An Extension of a Phase I Pilot Study of MitapivatNo longer recruiting/follow-up only18-70 YearsNHLBIProgressive
21-I-0029Natural history, epidemiology and pathogenesis of severe HPV-related diseases (Neptune)Participants currently recruited/enrolled3-125 YearsNIAIDMultiple
21-C-0024A Phase 2 Adaptive Study of Subcutaneous Daratumumab, Once Weekly Carfilzomib, and Dexamethasone (DKd) in Patients with High-Risk Smoldering Multiple MyelomaParticipants currently recruited/enrolled18-125 YearsNCI Multiple
21-C-0021SARC037: A Phase I/II Study to Evaluate the Safety of Trabectedin Administered as a 1-Hour Infusion in Ewing Sarcoma Patients in Combination with Low Dose Irinotecan and 3'-Deoxy-3'-18F Fluorothymidine (18F-FLT) ImagingParticipants currently recruited/enrolled6-125 YearsNCI Multiple
20-M-0157PET Imaging of Cyclooxygenase in Participants with Major Depressive Disorder (MDD)Participants currently recruited/enrolled18-70 YearsNIMH Secondary
20-D-0131Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sj(SqrRoot)(Delta)gren's Syndrome; a Phase Ib-IIa Placebo-controlled Clinical Trial and Associated Mechanistic StudiesParticipants currently recruited/enrolled18-75 YearsNIDCRMultiple
20-C-0127A Phase 1 Study of Romidepsin, CC-486 (5-azacitidine), dexamethasone, and lenalidomide (RAdR) for relapsed/refractory T-cell malignanciesParticipants currently recruited/enrolled18-125 YearsNCI Secondary
20-C-0010Phase II Trial of Radium-223 in Biochemically Recurrent Prostate CancerParticipants currently recruited/enrolled18-125 YearsNCI Secondary
19-M-0095PET Imaging of Neuroinflammation in Neurodegenerative Diseases via a Novel TSPO RadioligandParticipants currently recruited/enrolled18-125 YearsNIMH Progressive
19-H-0097A Pilot Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Escalating Multiple Oral Doses of AG-348 in Subjects with Stable Sickle Cell DiseaseCompleted Study; data analyses ongoing18-70 YearsNHLBIMultiple
19-H-0088NHLBI DIR Transcatheter Mitral Cerclage Annuloplasty Early Feasibility StudyNo longer recruiting/follow-up only21-99 YearsNHLBISecondary
19-H-0057Multiple Patient Program for Lamprene (clofazimine) for the treatment of Non-Tuberculous Mycobacterial (NTM) Infections- CLAM320B2002MParticipants currently recruited/enrolled18-99 YearsNHLBIMultiple
19-DK-0050The Use of 124-I-PET/CT Whole Body and Lesional Dosimetry in Differentiated Thyroid CancerParticipants currently recruited/enrolled18-125 YearsNIDDKSecondary
19-C-0142Identifying Predictors of Poor Health-Related Quality-of-Life Among Pediatric Hematopoietic Stem Cell DonorsParticipants currently recruited/enrolled5-125 YearsNCI Multiple
19-C-0131Development and Psychometric Testing of a Pediatric Chronic Graft- Versus-Host Disease (GVHD) Symptom Scale (PCSS)Participants currently recruited/enrolled5-125 YearsNCI Multiple
19-C-0112Phase I/II Study De-intensifying Exposure of Post-transplantation Cyclophosphamide as GVHD Prophylaxis after HLA-haploidentical Hematopoietic Cell Transplantation for Hematologic MalignanciesParticipants currently recruited/enrolled12-125 YearsNCI Multiple
19-C-0103A Study of Temozolomide, Etoposide, Doxil, Dexamethasone, Ibrutinib, and Rituximab (TEDDI-R) in Aggressive B-cell Lymphomas with Secondary Involvement of the Central Nervous System (CNS)Participants currently recruited/enrolled18-125 YearsNCI Secondary
19-C-0102A Phase I Clinical Trial of T-cells Expressing an anti-SLAMF7 CAR for Treating Multiple MyelomaCompleted Study; data analyses ongoing18-73 YearsNCI Multiple
18-N-0140Clinical Laboratory Evaluation of Chronic Autonomic FailureParticipants currently recruited/enrolled18-125 YearsNINDSMultiple
18-M-0015Development of Non-Invasive Brain Stimulation TechniquesParticipants currently recruited/enrolled18-65 YearsNIMH Multiple
18-I-0139Defining Skin Immunity of a Bite of Key Insect Vectors in HumansCompleted Study; data analyses ongoing18-64 YearsNIAIDMultiple
18-H-0118Technical and Translational Development of Cardiovascular MRI (CMR)Participants currently recruited/enrolled7-125 YearsNHLBIMultiple
18-H-0003Discovery of Sirolimus Sensitive Biomarkers in BloodParticipants currently recruited/enrolled18-90 YearsNHLBIProgressive
18-D-0114An Open Label Pilot Study of Denosumab Treatment for Fibrous DysplasiaNo longer recruiting/follow-up only18-125 YearsNIDCRSecondary
18-CH-0002Investigations of Juvenile Neuronal Ceroid Lipofuscinosis (CLN3)Participants currently recruited/enrolled0-125 YearsNICHDMultiple
18-C-0125A Phase I Clinical Trial of T cells Expressing a Novel Fully-human Anti-BCMA CAR for Treating Multiple MyelomaNo longer recruiting/follow-up only18-73 YearsNCI Multiple
18-C-0110Safety Run-In and Phase II Trial of M7824 and Topotecan or Temozolomide in Relapsed Small Cell CancersParticipants currently recruited/enrolled18-125 YearsNCI Progressive
18-C-0062Phase 2 Trial of XL184 (Cabozantinib) an Oral Small-Molecule Inhibitor of Multiple Kinases, in Children and Young Adults with Refractory Sarcomas, Wilms Tumor, and Other Rare TumorsCompleted Study; data analyses ongoing2-30 YearsNCI Multiple
18-C-0058A Pilot Study to Evaluate the Effects of Castration on the Pharmacokinetics of Zolpidem After Single Dose Administration in Men with Prostate Cancer Undergoing Androgen Deprivation Therapy Compared to Normal Healthy FemalesParticipants currently recruited/enrolled18-125 YearsNCI Multiple
18-C-0049A Phase II Study Using the Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Neoantigens in Patients with Metastatic CancerParticipants currently recruited/enrolled18-72 YearsNCI Multiple
17-M-0181Recruitment and Characterization of Healthy Research Volunteers for NIMH Intramural StudiesParticipants currently recruited/enrolled18-125 YearsNIMH Secondary
17-I-0122NIAID Centralized Sequencing ProtocolParticipants currently recruited/enrolled0-125 YearsNIAIDProgressive
17-CC-0148Obtaining Samples from Human Subjects to Facilitate Basic, Translational and Clinical ResearchParticipants currently recruited/enrolled18-125 YearsCC Multiple
17-C-0175CC-4047-BRN-001: A Phase 2 Clinical Study of Pomalidomide (CC-4047) Monotherapy for Children and Young Adults with Recurrent or Progressive Primary Brain TumorsCompleted Study; data analyses ongoing3-20 YearsNCI Progressive
17-C-0140Phase I/II Evaluation of Oral Decitabine/Tetrahydrouridine as Epigenetic Priming for Pembrolizumab Immune Checkpoint Blockade in Inoperable Locally Advanced or Metastatic Non-Small Cell Lung Cancers, Esophageal Carcinomas, or Pleural MesotheliomasCompleted Study; data analyses ongoing18-99 YearsNCI Multiple
17-C-0115Phase I/II Study of T-DM1 Alone Versus T-DM1 and Metronomic Temozolomide in Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases Following Stereotactic RadiosurgeryNo longer recruiting/follow-up only18-125 YearsNCI Secondary
16-N-0072A Pilot Study of Adoptive Cellular Immunotherapy for Progressive Multifocal Leukoencephalopathy with Ex Vivo Generated Polyomavirus-Specific T-cellsCompleted Study; data analyses ongoing18-125 YearsNINDSProgressive
16-I-0078Microbial, Immune, and Metabolic Perturbations by Antibiotics (MIME study)Participants currently recruited/enrolled18-49 YearsNIAIDMultiple
16-HG-0026New Technology and Child HealthParticipants currently recruited/enrolled18-125 YearsNHGRIMultiple
16-HG-0017Genomic Services Research ProgramParticipants currently recruited/enrolled0-125 YearsNHGRISecondary
16-H-0132CADASIL Disease DiscoveryCompleted Study; data analyses ongoing18-100 YearsNHLBIProgressive
16-E-0006Investigating the Impact of Obesity on Pubertal Development in GirlsParticipants currently recruited/enrolled8-14 YearsNIEHSMultiple
16-C-0061Biospecimen Procurement for Center for Immuno-Oncology Immunotherapy ProtocolsParticipants currently recruited/enrolled18-125 YearsNCI Multiple
16-C-0047A Phase 1 Trial of Pomalidomide in Combination with Liposomal Doxorubicin in Patients with Advanced or Refractory Kaposi SarcomaParticipants currently recruited/enrolled18-125 YearsNCI Multiple
16-C-0003Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary ImmunodeficienciesParticipants currently recruited/enrolled4-75 YearsNCI Multiple
15-N-0126HERV-K Suppression using Antiretroviral Therapy in Volunteers with Amyotrophic Lateral Sclerosis (ALS)No longer recruiting/follow-up only18-125 YearsNINDSSclerosis
15-DK-0170Treatment of Chronic Delta Hepatitis with Lonafarnib and RitonavirCompleted Study; data analyses ongoing18-99 YearsNIDDKProgressive
15-C-0141Gene Therapy Follow up Protocol for Subjects Previously Enrolled in CAR T-Cell StudiesEnrolling by Invitation18-125 YearsNCI Multiple
15-C-0086Phase I Trial of the Combination of Nilotinib and Paclitaxel in Adults and Pediatric Patients with Refractory Solid TumorsParticipants currently recruited/enrolled12-120 YearsNCI Multiple
15-C-0078Safety and Feasibility of Stem Cell Gene Transfer Following R-EPOCH for Non-Hodgkin Lymphoma in AIDS Patients Using Peripheral Blood Stem/Progenitor Cells Treated with a Lentivirus Vector-Encoding Multiple Anti-HIV RNAsNo longer recruiting/follow-up only18-65 YearsNCI Multiple
15-C-0067A Phase I/II Open Label, Dose Escalation Study of Palifermin (Kepivance) in Persons Undergoing Unrelated Donor Allogeneic Hematopoietic Cell TransplantationParticipants currently recruited/enrolled18-125 YearsNCI Multiple
15-AA-0186Development of Neuroimaging Methods to Assess the Neurobiology of AddictionParticipants currently recruited/enrolled18-125 YearsNIAAAMultiple
14-N-0061Noninvasive Pre-surgical Evaluation of Patients with Focal Epilepsy and Establishment of a Normative Imaging DatabaseParticipants currently recruited/enrolled8-65 YearsNINDSSecondary
14-I-0091Analysis of Patients Treated for Chronic Granulomatous Disease Since January 1, 1995Completed Study; data analyses ongoing3-125 YearsNIAIDMultiple
14-I-0020Hematopoietic Stem Cell Mobilization in Idiopathic CD4 Lymphocytopenia Patients and Healthy Controls for the Study of T Cell Maturation and Trafficking in Murine ModelsParticipants currently recruited/enrolled18-65 YearsNIAIDSecondary
14-H-0127Characterization of the Pathogenesis of Primary and Secondary Lymphatic DisordersParticipants currently recruited/enrolled2-90 YearsNHLBISecondary
14-EI-0064Whole Exome and Whole Genome Sequencing for Genotyping of Inherited and Congenital Eye ConditionsParticipants currently recruited/enrolled1-125 YearsNEI Secondary
14-CC-0027The NIH Exercise Therapy for Advanced Lung Disease Trials: Response and Adaptation to Aerobic Exercise in Patients with Interstitial Lung DiseaseParticipants currently recruited/enrolled21-80 YearsCC Progressive
14-C-0157Phase 1 Study of Ibrutinib and Immuno-Chemotherapy Using Temozolomide, Etoposide, Doxil, Dexamethasone, Ibrutinib, Rituximab (TEDDI-R) in Primary CNS LymphomaParticipants currently recruited/enrolled18-125 YearsNCI Secondary
14-C-0059A Phase I Trial of T Cells Expressing an Anti-GD2 Chimeric Antigen Receptor in Children and Young Adults with GD2+ Solid TumorsCompleted Study; data analyses ongoing1-35 YearsNCI Secondary
14-C-0037A Phase 2 Study of the MET Kinase Inhibitor INC280 in Papillary Renal Cell CancerCompleted Study; data analyses ongoing18-125 YearsNCI Progressive
14-C-0015Pilot Trial of BMN 673, an Oral PARP Inhibitor, in Patients With Advanced Solid Tumors and Deleterious BRCA MutationsCompleted Study; data analyses ongoing18-125 YearsNCI Secondary
14-C-0004A Multicenter Phase 2 Study of the Bruton's Tyrosine Kinase Inhibitor PCI-32765 (Ibrutinib) for Treatment of Relapsed Hairy Cell LeukemiaNo longer recruiting/follow-up only18-125 YearsNCI Progressive
14-C-0001Phase II Study of Axitinib (AG-013736) with Evaluation of the VEGF-pathway in Metastatic, Recurrent or Primary Unresectable Pheochromocytoma/ParagangliomaCompleted Study; data analyses ongoing18-125 YearsNCI Progressive
13-N-0188Natural History and Biomarkers of C9ORF72 Amyotrophic Lateral Sclerosis and Frontotemporal DementiaCompleted Study; data analyses ongoing18-125 YearsNINDSSclerosis
13-HG-0158Patient Perspectives and Simulated Clinical InteractionsCompleted Study; data analyses ongoing18-50 YearsNHGRIMultiple
13-H-0051Bronchodilator Effects of Nebulized versus Inhaled Albuterol in Subjects with LymphangioleiomyomatosisParticipants currently recruited/enrolled18-125 YearsNHLBIProgressive
13-C-0152A Phase I Study of Autologous Activated Natural Killer (NK) Cells +/- rhIL15 in Children and Young Adults with Refractory Solid TumorsCompleted Study; data analyses ongoing2-29 YearsNCI Secondary
12-N-0095Clinical and Molecular Manifestations of Neuromuscular and Neurogenetic Disorders of ChildhoodParticipants currently recruited/enrolled0-125 YearsNINDSMultiple
12-HG-0022Inherited Diseases, Caregiving, and Social NetworksCompleted Study; data analyses ongoing18-125 YearsNHGRIMultiple
12-DA-N474Identifying Neurobiological Mechanisms that Underlie Acute Nicotine Withdrawal and Drive Early Relapse in SmokersClinical hold/Recruitment or enrollment suspended18-65 YearsNIDA Multiple
12-CC-0211A Pilot Study of the Effect of Spironolactone Therapy on Exercise Capacity and Endothelial Dysfunction in Pulmonary Arterial HypertensionParticipants currently recruited/enrolled18-125 YearsCC Progressive
12-CC-0139Estimation of Brain Biomechanics using MRIParticipants currently recruited/enrolled18-65 YearsCC Multiple
12-C-0193Lymphoid Malignancies and Precursors: Tissue Acquisition ProtocolParticipants currently recruited/enrolled18-125 YearsNCI Multiple
12-C-0178Longitudinal Assessment and Natural History Study of Children and Adults with MEN2A or MEN2B with or without Medullary Thyroid CarcinomaParticipants currently recruited/enrolled0-125 YearsNCI Multiple
12-C-0107Carfilzomib, Lenalidomide, and Dexamethasone in High-Risk Smoldering Multiple Myeloma: a Clinical and Correlative Pilot StudyNo longer recruiting/follow-up only18-125 YearsNCI Multiple
12-C-0074Mobilization and Collection of Autologous Hematopoietic Progenitor Cell (HPC) for Transplantation (AHCT) for Plasma Cell Myeloma (PCM)Completed Study; data analyses ongoing18-75 YearsNCI Multiple
10-M-0027Cognitive Neuroscience of Autism Spectrum DisordersParticipants currently recruited/enrolled5-89 YearsNIMH Multiple
10-DA-N457Characterization of Phenotypic and Genotypic RegressorsParticipants currently recruited/enrolled18-125 YearsNIDA Multiple
09-I-0126Pathogenesis and Genetic Basis of Physical Induced Urticarial SyndromesParticipants currently recruited/enrolled2-90 YearsNIAIDMultiple
09-C-0025Phase II Trial of LMB-2, Fludarabine and Cyclophosphamide for Adult T-Cell LeukemiaNo longer recruiting/follow-up only18-125 YearsNCI Secondary
09-C-0024A Phase I Study of Quadrivalent Human Papilloma Virus (HPV) (Types 6, 11, 16, 18) Recombinant Vaccine in HIV-Infected and HIV-Negative Pre-Adolescents, Adolescents and Young AdultsCompleted Study; data analyses ongoing12-26 YearsNCI Multiple
09-C-0005Randomized Trial of Cladribine (CdA) with Simultaneous or Delayed Rituximab to Eliminate Hairy Cell Leukemia Minimal Residual DiseaseParticipants currently recruited/enrolled18-125 YearsNCI Secondary
08-H-0186Safety and the Anti- Tumor Effects of Escalating Doses of Adoptively Infused Ex Vivo Expanded Autologous Natural Killer (NK) Cells Against Metastatic Cancers or Hematological Malignancies Sensitized to NK-TRAIL Cytotoxicity with BortezomibCompleted Study; data analyses ongoing18-70 YearsNHLBIMultiple
08-C-0130A Phase II Trial of Peginterferon alfa-2b (PEG-Intron) for Neurofibromatosis Type 1 Related Unresectable, Symptomatic or Life-Threatening Plexiform NeurofibromasCompleted Study; data analyses ongoing0-21 YearsNCI Progressive
07-C-0195Phase II Trial of Targeted Immune-Depleting Chemotherapy and Reduced-Intensity Allogeneic Hematopoietic Stem Cell Transplantation Using 8/8 and 7/8 HLA-matched Unrelated Donors and Utilizing Two Graft-versus-Host Disease Prophylaxis Regimens for the TreaCompleted Study; data analyses ongoing18-74 YearsNCI Multiple
06-I-0153A Pilot Study of Hepatic Fibrosis in HIV/AIDS Patients with Chronically Elevated Transaminases on Antiretroviral TherapyNo longer recruiting/follow-up only18-100 YearsNIAIDProgressive
06-CH-0186Evaluation of Biochemical Markers and Clinical Investigation of Niemann-Pick Disease, Type CParticipants currently recruited/enrolled0-125 YearsNICHDProgressive
06-C-0213Tissue Procurement Protocol for the Developmental Therapeutics Clinic, National Cancer Institute (NCI)Participants currently recruited/enrolled0-125 YearsNCI Multiple
05-H-0130Long-Term Evaluation and Follow Up Care of Patients Treated with Allogeneic Stem Cell TransplantsParticipants currently recruited/enrolled7-80 YearsNHLBIMultiple
04-H-0161Studies of the Natural History of Sickle Cell DiseaseParticipants currently recruited/enrolled2-125 YearsNHLBIMultiple
04-C-0281Natural History Study of Clinical and Biological Factors Determining Outcomes in Chronic Graft-Versus-Host DiseaseParticipants currently recruited/enrolled1-125 YearsNCI Multiple
04-C-0274Follow-Up Study of Subjects Previously Enrolled in Immunotherapy Studies Utilizing Gene Transfer or Other Immunotherapeutic AgentsParticipants currently recruited/enrolled18-125 YearsNCI Secondary
03-DK-0257Phase II Trial of Effect of Metreleptin Therapy in Severe Insulin ResistanceNo longer recruiting/follow-up only5-125 YearsNIDDKSecondary
03-C-0066Hereditary Leiomyomatosis Renal Cell Cancer (HLRCC): Identification of the Disease Gene, and Characterization of the Predisposition to Renal CancerParticipants currently recruited/enrolled2-125 YearsNCI Multiple
03-AG-0325The Baltimore Longitudinal Study of Aging(BLSA)Participants currently recruited/enrolled20-125 YearsNIA Multiple
02-I-0147Genetic Studies of Chronic Active Epstein-Barr Virus InfectionParticipants currently recruited/enrolled1-125 YearsNIAIDSecondary
02-H-0250A Phase I/II Study of HLA-matched Mobilized Peripheral Blood Hematopoietic Stem Cell Transplantation for Advanced Mycosis Fungoides/Sezary Syndrome Using Nonmyeloablative Conditioning with Campath-1HCompleted Study; data analyses ongoing18-125 YearsNHLBIMultiple
02-C-0268Prospective Study of Prophylactic Salpingo-Oophorectomy and Longitudinal CA-125 Screening Among Women at Increased Genetic Risk of Ovarian CancerCompleted Study; data analyses ongoing19-100 YearsNCI Multiple
02-C-0052Etiologic Investigation of Cancer Susceptibility in Inherited Bone Marrow Failure Syndromes: A Natural History StudyParticipants currently recruited/enrolled0-125 YearsNCI Secondary
01-M-0192Fluoxetine's Effects on Attention and Emotional Memory in Anxious and Depressed Youth and AdultsParticipants currently recruited/enrolled8-65 YearsNIMH Secondary
01-H-0088Determining the Prevalence and Prognosis of Secondary Pulmonary Hypertension in Adult Patients with Sickle Cell AnemiaCompleted Study; data analyses ongoing18-125 YearsNHLBISecondary
00-CH-0136A Trial of Pamidronate in Children with Osteogenesis ImperfectaCompleted Study; data analyses ongoing2-17 YearsNICHDMultiple
00-CH-0093Diagnosis, Pathophysiology, and Molecular Biology of Pheochromocytoma and ParagangliomaParticipants currently recruited/enrolled3-125 YearsNICHDMultiple
99-H-0050Non-Myeloablative Allogeneic Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Hematologic Malignancies in High Risk Patients and in Patients with Debilitating Hematologic DiseasesCompleted Study; data analyses ongoing2-80 YearsNHLBIMultiple
98-CH-0081Clinical and Basic Investigations into Smith-Lemli-Opitz SyndromeCompleted Study; data analyses ongoing0-125 YearsNICHDMultiple
96-H-0100Role of Genetic Factors in the Pathogenesis of Lung DiseaseParticipants currently recruited/enrolled2-90 YearsNHLBISclerosis
95-H-0186Characterization of the Pathogenesis of Lymphangioleiomyomatosis (LAM)Participants currently recruited/enrolled16-125 YearsNHLBISclerosis
95-CH-0059Definition of the Genotype and Clinical Phenotype of Primary Pigmented Nodular Adrenocortical Disease (PPNAD), Carney Complex, Peutz-Jeghers Syndrome and Related ConditionsCompleted Study; data analyses ongoing3-70 YearsNICHDMultiple
92-I-0125A Study of Viral Burden in Peripheral Blood Versus Lymphoid and Bone Marrow Tissue in HIV-Infected IndividualsParticipants currently recruited/enrolled18-125 YearsNIAIDProgressive
91-CC-0117Epidemiology, Infectivity and Natural History of Hepatitis C Virus Infection in a Blood Donor PopulationNo longer recruiting/follow-up only18-125 YearsCC Secondary
78-C-0039Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of CancerNo longer recruiting/follow-up only0-125 YearsNCI Multiple
77-DK-0096Studies on Thyroid Nodules and Thyroid CancerParticipants currently recruited/enrolled0-125 YearsNIDDKProgressive
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