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186 Studies found from all possible combinations of your search terms. Select a protocol that you wish to review.
Protocol Number
Title
Protocol Status
Min-Max Age
Institute
Keywords
11-C-0190
Collection of Tissue Blocks or Slides from Patients with Cancer
Participants currently recruited/enrolled
18-125 Years
NCI
Benign Neoplasm
09-C-0242
Prospective Comprehensive Molecular Analysis of Endocrine Neoplasms
Participants currently recruited/enrolled
4-125 Years
NCI
Benign Neoplasm
00-CH-0160
Clinical and Molecular Analysis of ACTH-Independent Steroid Hormone Production in Adrenocortical Tissue
Completed Study; data analyses ongoing
3-70 Years
NICHD
Benign Neoplasm
001032-C
BAY 1895344 Plus Topoisomerase-1 (Top1) Inhibitors in Patients with Advanced Solid Tumors, Phase I Studies with Expansion Cohorts in Small Cell Lung Carcinoma (SCLC), Poorly Differentiated Neuroendocrine Carcinoma (PD-NEC) and Pancreatic Adenocarcinoma (
Recruitment has not started
18-125 Years
NCI
Neoplasm
000954-C
A Phase 1/2 Single Arm Open-Label Clinical Trial of TC-510 In Patients with Advanced Mesothelin-Expressing Cancer
Participants currently recruited/enrolled
18-125 Years
NCI
Neoplasm
000782-C
A Dose-Escalation and Expansion Study of the Safety and Pharmacokinetics of XL092 as Single-Agent and Combination Therapy in Subjects with Inoperable Locally Advanced or Metastatic Solid Tumors
Recruitment has not started
18-125 Years
NCI
Neoplasm
000732-C
A Long-Term Follow-Up Study of Patients Who Received VOR33
Recruitment has not started
18-125 Years
NCI
Neoplasm
000707-I
Respiratory Virus Sampling and Repository
Participants currently recruited/enrolled
3-125 Years
NIAID
Respiratory
000697-H
U01 Cooperative Assessment of Late Effects for SCD Curative Therapies (COALESCE)
Participants currently recruited/enrolled
18-65 Years
NHLBI
Neoplasm
000678-C
Rare Tumors and Cancer Predisposition in Individuals and Families
Participants currently recruited/enrolled
0-125 Years
NCI
Neoplasm
000666-C
A Phase I/II Study of Palbociclib and Sasanlimab for the Treatment of Advanced Clear Cell Renal Cell Carcinoma (ccRCC) or Papillary Renal Cell Carcinoma (pRCC)
Recruitment has not started
18-125 Years
NCI
Neoplasm
000661-C
Comprehensive Molecular and Clinical Evaluation of Pediatric and Adult Myelodysplastic Syndromes (MDS)
Participants currently recruited/enrolled
0-125 Years
NCI
Neoplasm
000611-C
A Phase II Trial of Focal Ultrahypofractionated Stereotactic Radiation Therapy for the Treatment of Unifocal Prostate Cancer
Recruitment has not started
18-125 Years
NCI
Neoplasm
000580-C
A Phase 1/2, Open Label Dose-Escalation and Expansion Trial of Nkt2152, an Orally Administered Hif2a Inhibitor, to Investigate Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity in Patients with Advanced Clear Cell Renal Cell Carcinoma
Participants currently recruited/enrolled
18-125 Years
NCI
Neoplasm
000491-C
Tissue Procurement and Natural History Study of Neuroendocrine Neoplasms (NENs) Including Adrenocortical Carcinoma (ACC)
Participants currently recruited/enrolled
18-125 Years
NCI
Neoplasm
000489-C
Phase I/II Study Using Prophylactic Donor Lymphocyte Infusion Early Post-Transplant After Allogeneic Hematopoietic Cell Transplantation Using Post-Transplantation Cyclophosphamide for High-Risk Hematologic Malignancies
Clinical hold/Recruitment or enrollment suspended
12-125 Years
NCI
Neoplasm
000473-C
A Randomized Phase II Study of Systemic Chemotherapy with or without HAI FUDR-Dexamethasone in Patients with Unresectable Intrahepatic Cholangiocarcinoma
Participants currently recruited/enrolled
18-125 Years
NCI
Neoplasm
000464-H
Evaluation of Clonal Hematopoiesis in Patients with Sickle Cell Disease Receiving Curative Therapies
Enrolling by Invitation
4-125 Years
NHLBI
Neoplasm
000410-I
VRC 325 (000410): A Phase I Open-Label Clinical Trial to Evaluate the Dose, Safety, Tolerability and Immunogenicity of Mosaic Quadrivalent Influenza Vaccine with and without Adjuplex Compared with a Licensed Inactivated Seasonal QIV, In Healthy Adults
Participants currently recruited/enrolled
18-50 Years
NIAID
Respiratory
000359-C
Phase I/II study to reduce post-transplantation cyclophosphamide dosing for older or unfit patients undergoing bone marrow transplantation for hematologic malignancies
Participants currently recruited/enrolled
12-85 Years
NCI
Neoplasm
000356-C
A Phase I/II Trial of BMS-986253 in Myelodysplastic Syndromes
Participants currently recruited/enrolled
18-125 Years
NCI
Neoplasm
000307-C
Phase II Study Evaluating the Efficacy of M9241 in Combination with Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects with Metastatic Colorectal Cancer or Intrahepatic Cholangiocarcinoma
Participants currently recruited/enrolled
18-125 Years
NCI
Neoplasm
000305-C
Exploratory Phase II Study of LAnreotide in Unresectable or Metastatic Pheochromocytoma / PARAganglioma
Participants currently recruited/enrolled
18-125 Years
NCI
Neoplasm
000302-C
A Multi-Center Natural History of Urothelial Cancer and Rare Genitourinary Tract Malignancies
Participants currently recruited/enrolled
18-125 Years
NCI
Neoplasm
000291-I
Observational Digital Biomarker Discovery in Respiratory Virus Challenge Studies
Recruitment has not started
18-65 Years
NIAID
Respiratory
000274-C
Phase I Trial of Pomalidomide and Dose-Adjusted EPOCH +/- Rituximab for HIV-Associated Lymphomas
Participants currently recruited/enrolled
18-125 Years
NCI
Neoplasm
000237-C
Phase II Study of Intravenous and Intraperitoneal Paclitaxel and Oral Nilotinib for Peritoneal Carcinomatosis from Colorectal, Appendiceal, Small Bowel, Gastric, Ovarian, or Other Gynecologic Primary Cancer
Participants currently recruited/enrolled
18-125 Years
NCI
Neoplasm
000134-I
A Phase 1b, Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation Trial of Intravenous Zotatifin in Adults with Mild or Moderate Coronavirus Disease 2019 (COVID-19)
Participants currently recruited/enrolled
18-125 Years
NIAID
Respiratory
000123-CC
Evaluation of Atherosclerotic Plaques in Abdominal CT Studies
No longer recruiting/follow-up only
0-125 Years
CC
Neoplasm
000103-C
A Randomized Study Investigating the Pharmacokinetics of Standard Interval Dosing Compared to Extended Interval Dosing of Nivolumab or Pembrolizumab in Locally Advanced or Metastatic Cancers
Participants currently recruited/enrolled
18-125 Years
NCI
Neoplasm
000077-DC
Collection of Clinical Data and Specimens for Research on Head and Neck and Communication Disorders
Participants currently recruited/enrolled
2-125 Years
NIDCD
Neoplasm
000067-C
Understanding the Patient Experience: Symptom Burden in Pediatric Patients Receiving Chimeric Antigen Receptor (CAR) T-cell Therapy
Participants currently recruited/enrolled
2-125 Years
NCI
Neoplasm
000046-C
Omics of Cancer: OncoGenomics
Recruitment has not started
0-125 Years
NCI
Neoplasm
000030-C
Phase 2 Study of Bintrafusp alfa in Recurrent/Metastatic Olfactory Neuroblastoma (BARON).
Participants currently recruited/enrolled
18-125 Years
NCI
Neoplasm
22-C-0005
Phase I Dose Escalation and Expansion Study of Tazemetostat in Combination with Topotecan and Pembrolizumab in Recurrent Small Cell Lung Cancer
Participants currently recruited/enrolled
18-125 Years
NCI
Neoplasm
21-I-0029
Natural history, epidemiology and pathogenesis of severe HPV-related diseases (Neptune)
Participants currently recruited/enrolled
3-125 Years
NIAID
Benign
21-CH-0028
A Pilot Study to Evaluate a Noninvasive Multimodal Biosensing Device for Screening and Monitoring Response to Treatment of Infectious Respiratory Diseases.
Participants currently recruited/enrolled
18-125 Years
NICHD
Respiratory
21-C-0032
GD2-CAR PERSIST: Production and Engineering of GD2-Targeted, Receptor Modified T Cells (GD2CART) for Osteosarcoma or Neuroblastoma to Increase Systemic Tumor Exposure
Participants currently recruited/enrolled
0-35 Years
NCI
Neoplasm
21-C-0022
A Phase 2 Single Arm Open-Label Clinical Trial of ADP-A2M4 SPEAR(TM) T Cells in Subjects with Advanced Synovial Sarcoma or Myxoid/Round Cell Liposarcoma
Participants currently recruited/enrolled
10-75 Years
NCI
Neoplasm
21-C-0013
A Phase I/II Study of Adjuvant PRGN-2012 in Adult Patients with Recurrent Respiratory Papillomatosis
Participants currently recruited/enrolled
18-125 Years
NCI
Respiratory
21-C-0006
Phase I/II Study Evaluating Safety and Efficacy of Tivozanib (AV-951) in Cholangiocarcinoma
Clinical hold/Recruitment or enrollment suspended
18-125 Years
NCI
Neoplasm
21-C-0001
A Phase I/II Study of M9241 in Combination with Docetaxel in Adults with Metastatic Castration Sensitive and Castration Resistant Prostate Cancer
Participants currently recruited/enrolled
18-125 Years
NCI
Neoplasm
20-N-0153
Acute effects of medium chain triglyceride (MCT) nutritional ketosis on Parkinson's Disease (PD) symptoms and biomarkers (MCT-PD)
Completed Study; data analyses ongoing
50-125 Years
NINDS
Respiratory
20-N-0019
The Effect of Vorinostat on ACTH Producing Pituitary Adenomas in Cushing's Disease
Participants currently recruited/enrolled
18-125 Years
NINDS
Benign
20-M-0157
PET Imaging of Cyclooxygenase in Participants with Major Depressive Disorder (MDD)
Participants currently recruited/enrolled
18-70 Years
NIMH
Respiratory
20-I-0160
Dose-Escalation Study of a Low Pathogenicity Avian H10N7 Influenza Virus in a Healthy Human Challenge Model
Recruitment has not started
18-50 Years
NIAID
Respiratory
20-I-0145
VRC 323: A Phase I Open-Label Clinical Trial to Evaluate the Dose, Safety, Tolerability and Immunogenicity of an Influenza H10 Stabilized Stem Ferritin Vaccine, VRC-FLUNPF0103-00-VP, in Healthy Adults
Completed Study; data analyses ongoing
18-70 Years
NIAID
Respiratory
20-I-0132
A Multicentre, Randomised, Double-blind, Parallel-group, Placebo-controlled, 24-week Phase 3 Study with an Open-label Extension to Evaluate the Efficacy and Safety of Benralizumab in Patients with Hypereosinophilic Syndrome (HES)
Participants currently recruited/enrolled
12-130 Years
NIAID
Respiratory
20-I-0123
A Longitudinal Study of COVID-19 Sequelae and Immunity
Participants currently recruited/enrolled
18-125 Years
NIAID
Respiratory
20-I-0117
Surveillance of Individuals Following SARS-CoV-2 infection
Completed Study; data analyses ongoing
18-125 Years
NIAID
Respiratory
20-I-0111
COVID-19-associated Lymphopenia Pathogenesis Study in Blood
Participants currently recruited/enrolled
18-125 Years
NIAID
Respiratory
20-I-0083
SARS-COV2 Pandemic Serosurvey and Blood Sampling
Completed Study; data analyses ongoing
18-125 Years
NIAID
Respiratory
20-D-0094
Transmissibility and Viral Load of SARS-CoV-2 Through Oral Secretions
Completed Study; data analyses ongoing
18-125 Years
NIDCR
Respiratory
20-C-0161
Prospective Study of Surgery in Gastrointestinal Stromal Tumors (GISTs) for Treatment, Tumor Modeling, and Genomic Analysis
Participants currently recruited/enrolled
6-125 Years
NCI
Neoplasm
20-C-0152
Phase II Study of combination of Trametinib (MEK inhibitor) and Hydroxychloroquine (HCQ) (autophagy inhibitor) in Patients with KRAS Mutation Refractory Bile Tract Carcinoma (BTC).
Participants currently recruited/enrolled
18-125 Years
NCI
Neoplasm
20-C-0150
Phase II Randomized Trial of Bethesda Protocol Compared to Cambridge Method for Detection of Early Stage Gastric Cancer in CDH1 Mutation Carriers
Recruitment has not started
18-125 Years
NCI
Neoplasm
20-C-0130
A Feasibility Study Investigating the Use of Machine Learning to Analyze Facial Imaging, Voice and Spoken Language for the Capture and Classification of Cancer/Tumor Pain
Enrolling by Invitation
12-125 Years
NCI
Neoplasm
20-C-0121
Rapid Analysis and Response Evaluation of Combination Anti-Neoplastic Agents in Rare Tumors (RARE CANCER) Trial: RARE 1 Nilotinib and Paclitaxel
Participants currently recruited/enrolled
18-125 Years
NCI
Neoplasm
20-C-0069
A First-In-Human Phase I Single-Agent Dose-Escalation, Food Effect and Dose Expansion Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms
Participants currently recruited/enrolled
18-125 Years
NCI
Neoplasm
20-C-0051
Gene Therapy Follow up Protocol for Subjects Previously Enrolled in NCI Genitourinary Malignancies Branch Studies
Enrolling by Invitation
18-125 Years
NCI
Neoplasm
20-C-0041
Protocol for a Research Database for Hematopoietic Cell Transplantation, Other Cellular Therapies and Marrow Toxic Injuries
Enrolling by Invitation
1-125 Years
NCI
Neoplasm
20-C-0028
Phase 1/2 Study of Anti-CD33 Chimeric Antigen Receptor-Expressing T Cells (CD33CART) in Children and Young Adults with Relapsed/Refractory Acute Myeloid Leukemia
Participants currently recruited/enrolled
3-35 Years
NCI
Neoplasm
20-C-0024
A Sequential Window of Opportunity Trial of Anti-PD-L1/TGF-beta trap (M7824 ) Alone and in Combination with TriAd Vaccine, and N-803 for Resectable Head and Neck Squamous Cell Carcinoma not Associated with Human Papillomavirus Infection.
No longer recruiting/follow-up only
18-125 Years
NCI
Neoplasm
20-C-0023
First-in-Human Phase I Trial to Investigate the Safety, Tolerability, Pharmacokinetics, Biological and Clinical Activity of Metarrestin (ML-246) in Subjects with Metastatic Solid Tumors
Participants currently recruited/enrolled
12-125 Years
NCI
Neoplasm
20-C-0022
Phase II trial of VB-111 in Combination with Nivolumab in Patients with Metastatic Colorectal Cancer (mCRC)
Completed Study; data analyses ongoing
18-125 Years
NCI
Neoplasm
20-C-0012
A Phase I Study of Bintrafusp alfa (M7824) and NHS-IL12 (M9241) Alone and in Combination with Stereotactic Body Radiation Therapy (SBRT) in Adults with Metastatic Non-Prostate Genitourinary Malignancies
Participants currently recruited/enrolled
18-125 Years
NCI
Neoplasm
19-I-0058
Mucosal Correlates of Protection After Influenza Viral Challenge of Vaccinated and Unvaccinated Healthy Volunteers
Completed Study; data analyses ongoing
18-55 Years
NIAID
Respiratory
19-DA-N075
Manipulating Ghrelin Signaling via GOAT Inhibition in Alcohol Use Disorder
Participants currently recruited/enrolled
18-70 Years
NIDA
Respiratory
19-C-0138
Phase I/II Study of Lu-177-DOTATATE (Lutathera) in Combination with Olaparib in Inoperable Gastroenteropancreatico Neuroendocrine Tumors (GEP-NET)
Participants currently recruited/enrolled
18-125 Years
NCI
Neoplasm
19-C-0128
A Phase I Study of Mesothelin-Targeted Immunotoxin LMB-100 in Combination with Tofacitinib in Persons with Previously Treated Pancreatic Adenocarcinoma, Cholangiocarcinoma and other Mesothelin Expressing Solid Tumors
Completed Study; data analyses ongoing
18-125 Years
NCI
Neoplasm
19-C-0117
A Phase 1 / 2 Single Arm Open-label Clinical Trial of Gavocabtagene Autoleucel (gavo-cel) in Patients with Advanced Mesothelin Expressing Cancer
Participants currently recruited/enrolled
18-120 Years
NCI
Neoplasm
19-C-0112
Phase I/II Study De-intensifying Exposure of Post-transplantation Cyclophosphamide as GVHD Prophylaxis after HLA-haploidentical Hematopoietic Cell Transplantation for Hematologic Malignancies
Participants currently recruited/enrolled
12-125 Years
NCI
Neoplasm
19-C-0040
Natural History Study of Men at High Genetic Risk for Prostate Cancer
Participants currently recruited/enrolled
30-75 Years
NCI
Neoplasm
19-C-0016
Natural History and Biospecimen Acquisition Study for Children and Adults with Rare Solid Tumors
Participants currently recruited/enrolled
0-125 Years
NCI
Neoplasm
18-N-0133
Feasibility of Endosphenoidal Coil Placement for Imaging of the Sella During Transsphenoidal Surgery
Participants currently recruited/enrolled
18-125 Years
NINDS
Neoplasm
18-I-0039
Challenge Infection of Healthy Adult Volunteers with RSV A2
Completed Study; data analyses ongoing
18-50 Years
NIAID
Respiratory
18-DC-0051
Biospecimen Procurement for NIDCD Clinical Protocols
Participants currently recruited/enrolled
0-99 Years
NIDCD
Neoplasm
18-CH-0031
Clinical and Molecular Characteristics of Primary Aldosteronism in Blacks
Participants currently recruited/enrolled
7-70 Years
NICHD
Neoplasm
18-C-0126
NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice)
Completed Study; data analyses ongoing
1-21 Years
NCI
Neoplasm
18-C-0093
Pilot Study of Medication Adherence in Children, Adolescents, and Adults with Neurofibromatosis Type 1 (NF1) on Clinical Treatment Trials
No longer recruiting/follow-up only
3-125 Years
NCI
Benign
18-C-0078
A Phase I/II Study of Immunotherapy Combination BN-Brachyury vaccine, M7824, N-803 and Epacadostat (QuEST1)
Participants currently recruited/enrolled
18-125 Years
NCI
Neoplasm
18-C-0076
Bicalutamide With or Without Metformin for Biochemical Recurrence in Prostate Cancer Patients (BIMET-1)
Completed Study; data analyses ongoing
18-85 Years
NCI
Neoplasm
18-C-0058
A Pilot Study to Evaluate the Effects of Castration on the Pharmacokinetics of Zolpidem After Single Dose Administration in Men with Prostate Cancer Undergoing Androgen Deprivation Therapy Compared to Normal Healthy Females
Participants currently recruited/enrolled
18-125 Years
NCI
Neoplasm
18-C-0028
A Phase I Trial of Highly Conformal, Hypofractionated, Focally Dose Escalated Post-Prostatectomy Radiotherapy
Participants currently recruited/enrolled
18-125 Years
NCI
Neoplasm
18-C-0014
Phase I Trial of 5-aza-4'-thio-2'-Deoxycytidine (Aza-TdC) in Patients with Advanced Solid Tumors
Participants currently recruited/enrolled
18-120 Years
NCI
Neoplasm
18-C-0008
Phase III Randomized Adjuvant study of Pembrolizumab in muScle invaSive and locAlly aDvanced urOthelial caRcinoma (AMBASSADOR) versus Observation
No longer recruiting/follow-up only
18-125 Years
NCI
Neoplasm
17-DC-0138
Observational Study of Hearing Loss and the Effects of Statin Drugs in Head and Neck Squamous Cell Carcinoma Patients Treated with Cisplatin Chemoradiation
Completed Study; data analyses ongoing
18-125 Years
NIDCD
Neoplasm
17-C-0158
A Feasibility Study of Mobile Sensor Technologies to Assess General Symptomology of Cancer Patients
Enrolling by Invitation
18-125 Years
NCI
Neoplasm
17-C-0157
A Phase I Single-Arm Study of the Combination of Durvalumab (MEDI4736) and Vicineum (oportuzumab monatox, VB4-845) in Subjects with High-Grade Non-Muscle-Invasive Bladder Cancer Previously Treated with Bacillus Calmette-Gu(SqrRoot)(Copyright)rin (BCG)
Participants currently recruited/enrolled
18-125 Years
NCI
Neoplasm
17-C-0156
Longitudinal Sample Collection and Tracking for the Developmental Therapeutics Clinic, National Cancer Institute
Participants currently recruited/enrolled
18-125 Years
NCI
Neoplasm
17-C-0153
Phase I Trial of Image Guided Focally Dose Escalated Prostate SBRT for Locally Recurrent Prostate Cancer after Prior Radiotherapy
Participants currently recruited/enrolled
18-125 Years
NCI
Neoplasm
17-C-0117
A Phase 1/2a, Open-Label, Multicenter Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Anti-Tumor Activity of PEN-866 in Advanced Solid Malignancies
Completed Study; data analyses ongoing
18-125 Years
NCI
Neoplasm
17-C-0109
18F-DCFPyL PET/CT in High Risk and Recurrent Prostate Cancer
Enrolling by Invitation
18-125 Years
NCI
Neoplasm
17-C-0092
A Phase I/II Study of Pexa-Vec Oncolytic Virus in Combination with Immune Checkpoint Inhibition in Refractory Colorectal Cancer
Completed Study; data analyses ongoing
18-125 Years
NCI
Neoplasm
17-C-0089
Evaluation of 18F-DCFPyL PSMA- versus 18F-NaF-PET imaging for Detection of Metastatic Prostate Cancer
Enrolling by Invitation
18-125 Years
NCI
Neoplasm
17-C-0087
Lu-177-DOTATATE (Lutathera) in Therapy of Inoperable Pheochromocytoma/ Paraganglioma
Participants currently recruited/enrolled
18-125 Years
NCI
Neoplasm
17-C-0044
Prospective Evaluation and Molecular Profiling in Patients with Gastric Tumors
Participants currently recruited/enrolled
2-125 Years
NCI
Neoplasm
17-C-0043
Hereditary Gastric Cancer Syndromes: An Integrated Genomic and Clinicopathologic Study of the Predisposition to Gastric Cancer
Participants currently recruited/enrolled
2-125 Years
NCI
Neoplasm
16-N-0041
Tumor Related Epilepsy
Participants currently recruited/enrolled
8-125 Years
NINDS
Neoplasm
16-E-0096
Cytochrome P450 Epoxygenase Pathway Regulation of Macrophage Function
Participants currently recruited/enrolled
18-65 Years
NIEHS
Respiratory
16-CC-0098
Pilot Study of Ultrasound Guided Focal Thermal Ablation of Prostate Cancer
Clinical hold/Recruitment or enrollment suspended
18-125 Years
CC
Neoplasm
16-CC-0049
A Phase II Study Using LC Bead LUMI Radio-Opaque Embolic Beads to Detect and Characterize the Vascularity of Hepatic Tumors During Treatment with Transarterial Embolization (TAE) Alone or Combined with Thermal Ablation
Enrolling by Invitation
18-125 Years
CC
Neoplasm
16-C-0171
Phase I/II Study of Lenalidomide Combined with Modified DA-EPOCH and Rituximab (EPOCH-R2) in Primary Effusion Lymphoma or KSHV-Associated Large Cell Lymphoma
Participants currently recruited/enrolled
18-125 Years
NCI
Neoplasm
16-C-0154
A Phase I/II Trial of T Cell Receptor Gene Therapy Targeting HPV-16 E7 for HPV-Associated Cancers
Participants currently recruited/enrolled
18-125 Years
NCI
Neoplasm
16-C-0151
Evaluation of the Natural History of and Specimen Banking for Patients with Tumors of the Central Nervous System
Participants currently recruited/enrolled
18-125 Years
NCI
Neoplasm
16-C-0135
A Pilot Study of Combined Immune Checkpoint Inhibition in combination with Ablative Therapies in Subjects with Hepatocellular Carcinoma (HCC) or Biliary Tract Carcinomas (BTC)
No longer recruiting/follow-up only
18-125 Years
NCI
Neoplasm
16-C-0128
A Phase I/II Study of Mesothelin-Targeted Immunotoxin LMB-100 Alone or in Combination with Nab-Paclitaxel in Participants with Previously Treated Metastatic and/ or Locally Advanced Pancreatic Ductal Adenocarcinoma and Mesothelin Expressing Solid Tumors
Completed Study; data analyses ongoing
18-125 Years
NCI
Neoplasm
16-C-0121
A Pilot Clinical Trial of Genomic Based Assignment of Therapy in Advanced Urothelial Carcinoma
Completed Study; data analyses ongoing
18-125 Years
NCI
Neoplasm
16-C-0107
A Phase I/II Trial of EP0057, a Nanoparticle Camptothecin with Olaparib in Patients with Relapsed/Refractory Small Cell Lung, Bladder and Prostate Cancers
Participants currently recruited/enrolled
18-125 Years
NCI
Neoplasm
16-C-0097
Phase 1 Trial of Panobinostat in Children with Diffuse Intrinsic Pontine Glioma
Completed Study; data analyses ongoing
2-21 Years
NCI
Neoplasm
16-C-0092
A Pilot Study of Local Ablative Therapy for Treatment of Oligoprogressive, EGFR-mutated, Non-Small Cell Lung Cancer (NSCLC) After Treatment with Osimertinib (AZD9291, Tagrisso)
Completed Study; data analyses ongoing
18-125 Years
NCI
Neoplasm
16-C-0087
Phase I Study of Veliparib (ABT-888), an Oral PARP Inhibitor, and VX-970, an ATR Inhibitor in Combination with Cisplatin in Patients with Refractory Solid Tumors
Completed Study; data analyses ongoing
18-125 Years
NCI
Neoplasm
16-C-0066
Phase I Study of MK-3475 (Pembrolizumab) in Patients with Human Immunodeficiency Virus (HIV) and Relapsed/Refractory or Disseminated Malignant Neoplasm
Participants currently recruited/enrolled
18-125 Years
NCI
Neoplasm
16-C-0048
Docetaxel and Prostvac for Metastatic Castration Sensitive Prostate Cancer
No longer recruiting/follow-up only
18-125 Years
NCI
Neoplasm
16-C-0034
A Phase II Trial of Oral Pazopanib plus Oral Topotecan Metronomic Antiangiogenic Therapy for Recurrent Glioblastoma Multiforme (A) without Prior Bevacizumab Exposure and (B) after Failing Prior Bevacizumab
Completed Study; data analyses ongoing
18-125 Years
NCI
Neoplasm
15-I-0148
A Phase I Study of Respiratory Syncytial Virus Human Challenge in Healthy Adult Volunteers
Completed Study; data analyses ongoing
18-50 Years
NIAID
Respiratory
15-I-0056
Collection of Plasma from Subjects that Recovered From or Were Vaccinated To Emerging Infectious Diseases
Enrolling by Invitation
18-70 Years
NIAID
Respiratory
15-H-0172
A Pilot Phase II Study Using Ibrutinib and Short-Course Fludarabine in Previously Untreated Patients with Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)
No longer recruiting/follow-up only
18-125 Years
NHLBI
Neoplasm
15-C-0205
Phase II Randomized, Placebo-Controlled Trial of PROSTVAC (PSA-TRICOM) in Patients with Clinically Localized Prostate Cancer Undergoing Active Surveillance
Completed Study; data analyses ongoing
18-99 Years
NCI
Neoplasm
15-C-0200
Molecular Analysis for Therapy Choice (MATCH) (EAY131)
Completed Study; data analyses ongoing
18-125 Years
NCI
Neoplasm
15-C-0160
A Phase I Study of Cabozantinib Plus Nivolumab (CaboNivo) Alone or in Combination with Ipilimumab (CaboNivoIpi) in Patients with Advanced/Metastatic Urothelial Carcinoma and other Genitourinary Tumors
No longer recruiting/follow-up only
18-125 Years
NCI
Neoplasm
15-C-0150
A Phase I/II Trial of Topotecan with VX-970 (M6620), an ATR Kinase Inhibitor in Small Cell Cancers
No longer recruiting/follow-up only
18-125 Years
NCI
Neoplasm
15-C-0145
Phase I/II Study of the Anti-Programmed Death Ligand-1 Antibody Durvalumab (MEDI4736) in Combination with Olaparib and/or Cediranib for Advanced Solid Tumors and Advanced or Recurrent Ovarian, Triple Negative Breast, Lung, Prostate and Colorectal Cancers
Participants currently recruited/enrolled
18-125 Years
NCI
Neoplasm
15-C-0138
Phase I Study of Ipilimumab, Nivolumab, and the Combination in Patients with Newly Diagnosed Glioblastoma
Completed Study; data analyses ongoing
18-125 Years
NCI
Neoplasm
15-C-0116
Phase I Trial of 4'-thio-2'-deoxycytidine (TdCyd) in Patients With Advanced Solid Tumors
Clinical hold/Recruitment or enrollment suspended
18-125 Years
NCI
Neoplasm
15-C-0086
Phase I Trial of the Combination of Nilotinib and Paclitaxel in Adults and Pediatric Patients with Refractory Solid Tumors
Participants currently recruited/enrolled
12-120 Years
NCI
Neoplasm
15-C-0076
A Pilot Study of Long Term TARP Vaccination Using A Multi-Epitope TARP Peptide Autologous Dendritic Cell Vaccination in Previously Vaccinated Men on NCI 09-C-0139
Completed Study; data analyses ongoing
18-125 Years
NCI
Neoplasm
15-C-0075
A Randomized, Placebo-Controlled Phase II Study of Multi-Epitope TARP Peptide Autologous Dendritic Cell Vaccination in Men with Stage D0 Prostate Cancer
Completed Study; data analyses ongoing
18-125 Years
NCI
Neoplasm
14-C-0163
Transformation of Plexiform Neurofibromas to Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis Type 1: Clinical, Histopathologic, and Genomic Analysis
Completed Study; data analyses ongoing
10-125 Years
NCI
Benign
14-C-0161
Phase I Trial of the Combination of Bortezomib and Clofarabine in Adults with Refractory Solid Tumors, Lymphomas, or Myelodysplastic Syndromes
Participants currently recruited/enrolled
18-125 Years
NCI
Neoplasm
14-C-0128
Collection of Pharmacokinetic Samples from Patients with Unanticipated Response, Significant Toxicity or Concern of Future Toxicity
Enrolling by Invitation
2-125 Years
NCI
Neoplasm
14-C-0056
Collection of Blood from Patients with Ovarian, Primary Peritoneal or Fallopian Tube Cancer
Completed Study; data analyses ongoing
18-125 Years
NCI
Neoplasm
13-DK-0200
The Mechanism of Human Non-Shivering Thermogenesis and Basal Metabolic Rate
Participants currently recruited/enrolled
18-35 Years
NIDDK
Respiratory
13-C-0202
Tissue Procurement and Natural History Study of Patients with Malignant Mesothelioma and Other Mesothelin Expressing Cancers
Participants currently recruited/enrolled
2-125 Years
NCI
Neoplasm
13-C-0176
Tumor, Normal Tissue and Specimens from Patients Undergoing Evaluation or Surgical Resection of Solid Tumors
Participants currently recruited/enrolled
2-125 Years
NCI
Neoplasm
13-C-0175
A Phase II Protocol for Subjects with Stage T1 Bladder Cancer to Evaluate Selective Bladder Preserving Treatment by Radiation Therapy Concurrent with Radio-sensitizing Chemotherapy following a Thorough Transurethral Surgical Re-Staging
Completed Study; data analyses ongoing
18-125 Years
NCI
Neoplasm
13-C-0119
Evaluation of Local Response of Prostate Cancer to Irradiation Using Multiparametric MRI and MR-Guided Biopsies
Participants currently recruited/enrolled
18-125 Years
NCI
Neoplasm
13-C-0105
Molecular Profiling-based Assignment of Cancer Therapy for Patients With Advanced Solid Tumors
Completed Study; data analyses ongoing
18-120 Years
NCI
Neoplasm
13-C-0016
A Phase I Study of an Adenoviral Transduced Autologous Dendritic Cell Vaccine Expressing Human HER2/neu ECTM in Adults with Tumors with 1-3+ HER2/neu Expression
Completed Study; data analyses ongoing
18-125 Years
NCI
Neoplasm
12-H-0064
A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs) for Transplantation in Pediatric and Adult Patients with Hematologic Malignancies and Other Indications
Participants currently recruited/enrolled
4-75 Years
NHLBI
Neoplasm
12-H-0035
A Phase II study of Ibrutinib for Patients with Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL) Who Need Therapy and are Older than 65 or have a 17p Deletion
No longer recruiting/follow-up only
18-125 Years
NHLBI
Neoplasm
12-C-0205
A Phase II Study of Cabozantinib (XL184) in Patients With Advanced/Metastatic Urothelial Carcinoma
Completed Study; data analyses ongoing
18-125 Years
NCI
Neoplasm
12-C-0118
A Phase II Study of Sunitinib in Patients with Advanced Relapsed or Refractory Thymoma or Thymic Carcinoma with at Least One Prior Line of Platinum-Based Systemic Chemotherapy
No longer recruiting/follow-up only
18-100 Years
NCI
Neoplasm
12-C-0081
Phase I/II Study of Cediranib and Olaparib in Combination for Treatment of Recurrent Papillary-Serous Ovarian, Fallopian Tube, or Peritoneal Cancer or for Treatment of Recurrent Triple-Negative Breast Cancer
No longer recruiting/follow-up only
18-125 Years
NCI
Neoplasm
12-C-0079
A Phase II Multicenter Study of AMG 386 and Abiraterone in Metastatic Castration Resistant Prostate Cancer
Completed Study; data analyses ongoing
18-125 Years
NCI
Neoplasm
12-C-0066
Phase I Trial of Oral 5-Fluoro-2'-Deoxycytidine with Oral Tetrahydrouridine in Patients with Advanced Solid Tumors
Completed Study; data analyses ongoing
18-125 Years
NCI
Neoplasm
11-I-0109
Viral Infections in Healthy and Immunocompromised Hosts
Participants currently recruited/enrolled
0-125 Years
NIAID
Respiratory
11-H-0046
Cross-Sectional Characterization of Idiopathic Bronchiectasis
Completed Study; data analyses ongoing
18-125 Years
NHLBI
Respiratory
11-E-0006
The Role of TGF-Beta in Asthmatic Epithelial Cell Susceptibility to RSV Infection
Completed Study; data analyses ongoing
18-60 Years
NIEHS
Respiratory
11-CC-0152
The Natural History of Liver Disease in a Cohort of Participants with Hepatitis B and/or Hepatitis C with or without HIV Infection
Completed Study; data analyses ongoing
18-99 Years
CC
Neoplasm
11-C-0255
Clinical, Epidemiologic, and Genetic Studies of Li-Fraumeni Syndrome
Participants currently recruited/enrolled
0-125 Years
NCI
Neoplasm
11-C-0247
A Randomized Phase II Study of Tecemotide in Combination with Standard Androgen Deprivation Therapy and Radiation Therapy for untreated, intermediate and High Risk Prostate Cancer Patients
Completed Study; data analyses ongoing
18-100 Years
NCI
Neoplasm
11-C-0140
A Phase I Study of Gemcitabine, Carboplatin and Lenalidomide (GCL) for Treatment of Patients with Advanced/Metastatic Urothelial Carcinoma (UC) and Other Solid Tumors
Completed Study; data analyses ongoing
18-125 Years
NCI
Neoplasm
11-C-0061
Phase I Trial of Z-Endoxifen in Adults with Refractory Hormone Receptor-Positive Breast Cancer, Desmoid Tumors, Gynecologic Tumors, or other Hormone Receptor-Positive Solid Tumors
No longer recruiting/follow-up only
18-125 Years
NCI
Neoplasm
10-I-0197
Admission and Management of Occupational or Other Exposures to Biodefense/Bioterrorism Agents or to Epidemic/Emerging Infectious Diseases
Participants currently recruited/enrolled
2-99 Years
NIAID
Respiratory
10-I-0109
VRC 900: Evaluation of Tissue-Specific Immune Responses in Adults 18 Years of Age and Older
Participants currently recruited/enrolled
18-125 Years
NIAID
Respiratory
10-I-0014
The Natural History of Severe Viral Infections and Characterization of Immune Defects
Participants currently recruited/enrolled
2-125 Years
NIAID
Respiratory
10-CC-0217
A Comparison of Methods for Assisting Needle Angle Selection During Image-Guided Tissue Biopsy
Completed Study; data analyses ongoing
18-125 Years
CC
Neoplasm
10-CC-0149
Comparing Expectorated and Induced Sputum and Pharyngeal Swabs for Cultures, AFB Smears, and Cytokines in Pulmonary Nontuberculous Mycobacterial Infection
Completed Study; data analyses ongoing
18-80 Years
CC
Respiratory
10-C-0056
A Phase I Study of Indenoisoquinolines LMP400 and LMP776 in Adults With Relapsed Solid Tumors and Lymphomas
Completed Study; data analyses ongoing
18-125 Years
NCI
Neoplasm
09-I-0232
FLU 003 Plus: An International Observational Study to Characterize Adults Who Are Hospitalized with Influenza or Other Targeted Respiratory Viruses
Participants currently recruited/enrolled
18-125 Years
NIAID
Respiratory
09-H-0172
Natural History of Bronchiectasis
Participants currently recruited/enrolled
5-125 Years
NHLBI
Respiratory
09-C-0139
A Pilot Study of Vaccination with Epitope-Enhanced TARP Peptide and TARP Peptide-Pulsed Dendritic Cells in the Treatment of Stage D0 Prostate Cancer
Completed Study; data analyses ongoing
18-125 Years
NCI
Neoplasm
09-C-0053
Autologous and Related/Unrelated Allogeneic Hematopoietic Stem Cell Transplant and Cellular Therapies Data Submission and Research Sample Collection to the Center for International Blood and Marrow Transplant Research (CIBMTR) and the National Marrow Don
Enrolling by Invitation
1-125 Years
NCI
Neoplasm
08-DK-N140
Predicting Adaptive Thermogenesis
Completed Study; data analyses ongoing
18-60 Years
NIDDK
Respiratory
08-C-0130
A Phase II Trial of Peginterferon alfa-2b (PEG-Intron) for Neurofibromatosis Type 1 Related Unresectable, Symptomatic or Life-Threatening Plexiform Neurofibromas
Completed Study; data analyses ongoing
0-21 Years
NCI
Benign
07-H-0142
Research Respiratory Tract Procedures
Participants currently recruited/enrolled
10-125 Years
NHLBI
Respiratory
07-DK-N215
Study of Short-Term Metabolic Adaptation: Prediction of Weight Change and Effects of Macronutrient Manipulations
Completed Study; data analyses ongoing
18-55 Years
NIDDK
Respiratory
07-C-0100
Collection of Blood from Patients with Prostate Cancer
Participants currently recruited/enrolled
18-125 Years
NCI
Neoplasm
06-C-0213
Tissue Procurement Protocol for the Developmental Therapeutics Clinic, National Cancer Institute (NCI)
Participants currently recruited/enrolled
0-125 Years
NCI
Neoplasm
06-C-0134
Natural History and Biology of Dermal Neurofibromas in Neurofibromatosis Type 1
Completed Study; data analyses ongoing
20-99 Years
NCI
Benign
05-CC-0091
Electromagnetic Tracking of Devices During Interventional Procedures
Enrolling by Invitation
18-125 Years
CC
Neoplasm
04-H-0012
Collection of Blood, Bone Marrow, Urine, and/or Tissue Samples from Patients with Solid Tumors, Hematological Malignancies or Non-Malignant Hematologic Disorders or HLA Compatible Family Members
Participants currently recruited/enrolled
2-125 Years
NHLBI
Neoplasm
04-C-0232
A Multi-Institutional Study of Proteomic Evaluation of Epithelial Ovarian Cancer, Primary Peritoneal Cancer, and Fallopian Tube Cancer Patients in First Clinical Remission: Development of a Protein Fingerprint Profile of Relapse
Completed Study; data analyses ongoing
18-125 Years
NCI
Neoplasm
04-C-0165
Data Collection, Clinical Care and Interventions in CCR, NCI
Enrolling by Invitation
0-125 Years
NCI
Neoplasm
03-C-0066
Hereditary Leiomyomatosis Renal Cell Cancer (HLRCC): Identification of the Disease Gene, and Characterization of the Predisposition to Renal Cancer
Participants currently recruited/enrolled
2-125 Years
NCI
Benign
02-I-0286
Efficacy of Tyrosine Kinase Inhibition in Reducing Eosinophilia in Patients with Myeloid and/or Steroid-Refractory Hypereosinophilic Syndrome
Participants currently recruited/enrolled
2-125 Years
NIAID
Neoplasm
02-C-0159
Birt-Hogg-Dub(SqrRoot)(Copyright) Syndrome: Characterization of the FLCN Disease Gene and Predisposition to Renal Cancer, Cutaneous Fibrofolliculoma and Pulmonary Cysts
Participants currently recruited/enrolled
2-125 Years
NCI
Neoplasm
99-I-0084
Studies of Human Pneumocystis Infection
Participants currently recruited/enrolled
3-99 Years
NIAID
Respiratory
99-C-0099
Examination of Clinical and Laboratory Abnormalities in Patients with Defective DNA Repair: Xeroderma Pigmentosum, Cockayne Syndrome, or Trichothiodystrophy
Participants currently recruited/enrolled
0-125 Years
NCI
Neoplasm
97-CH-0076
A Clinical and Genetic Investigation of Pituitary and HYPOTHALAMIC Tumors and Related Disorders
Participants currently recruited/enrolled
3-70 Years
NICHD
Neoplasm
97-C-0147
Collection of Serum and Tissue Samples from Patients with Biopsy-Proved or Suspected Malignant Diseases
Participants currently recruited/enrolled
2-125 Years
NCI
Neoplasm
94-HG-0132
The Phenotype and Etiology of Proteus Syndrome
Participants currently recruited/enrolled
0-125 Years
NHGRI
Benign
93-I-0063
Study of the Immunopathogenesis, Natural History, and Genetics of Autoimmune Lymphoproliferative Syndrome (ALPS) Associated with an Expansion of CD4-8-/TCR alpha/beta+ T Cells
Participants currently recruited/enrolled
0-99 Years
NIAID
Benign
92-CH-0034
Studies of Growth Deficiency and Growth Hormone Treatment in Children with Osteogenesis Imperfecta Types III and IV
Completed Study; data analyses ongoing
3-16 Years
NICHD
Respiratory
78-C-0039
Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of Cancer
No longer recruiting/follow-up only
0-125 Years
NCI
Neoplasm