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610 Studies found from all possible combinations of your search terms. Select a protocol that you wish to review.
Protocol Number Title Protocol Status Min-Max Age Institute Keywords
000678-CRare Tumors and Cancer Predisposition in Individuals and FamiliesParticipants currently recruited/enrolled0-125 YearsNCI Rare Genetic Bone
000213-HGClinical and Laboratory Study of Rare Skeletal DisordersParticipants currently recruited/enrolled0-125 YearsNHGRIRare Genetic Bone
19-HG-0059Longitudinal Studies of Patients with FPDMMParticipants currently recruited/enrolled0-125 YearsNHGRIRare Genetic Bone
12-H-0110An Open-label, Non-Randomized, Single-Arm Pilot Study to Evaluate the Effectiveness of Etidronate Treatment for Arterial Calcifications due to Deficiency in CD73 (ACDC)Completed Study; data analyses ongoing18-80 YearsNHLBIRare Genetic Bone
12-C-0178Longitudinal Assessment and Natural History Study of Children and Adults with MEN2A or MEN2B with or without Medullary Thyroid CarcinomaParticipants currently recruited/enrolled0-125 YearsNCI Rare Genetic Bone
11-C-0255Clinical, Epidemiologic, and Genetic Studies of Li-Fraumeni SyndromeParticipants currently recruited/enrolled0-125 YearsNCI Rare Genetic Bone
07-D-0016Effects of PTH Replacement on Bone in HypoparathyroidismCompleted Study; data analyses ongoing18-70 YearsNIDCRRare Genetic Bone
02-C-0313Cancer Risk in Xeroderma Pigmentosum HeterozygotesParticipants currently recruited/enrolled0-99 YearsNCI Rare Genetic Bone
00-HG-0153Investigations into Chediak-Higashi Syndrome and Related DisordersParticipants currently recruited/enrolled0-70 YearsNHGRIRare Genetic Bone
00-HG-0141Clinical, Biochemical, and Molecular Investigations into AlkaptonuriaParticipants currently recruited/enrolled2-125 YearsNHGRIRare Genetic Bone
94-I-0079Eosinophil Activation and Function in Parasitic Infections and Other Conditions with Increased Tissue or Peripheral Blood Eosinophilia in HumansParticipants currently recruited/enrolled1-100 YearsNIAIDRare Genetic Bone
001084-CHA Prospective Natural History Study of Lymphatic AnomaliesParticipants currently recruited/enrolled0-125 YearsNICHDGenetic Bone
001018-CHEstablishment of Genomic and Phenotypic Database for Niemann-Pick Disease, Type CParticipants currently recruited/enrolled0-125 YearsNICHDRare Genetic
000957-HGA Phase 1/2, Open-Label, Single Dose Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of SEL-302 (MMA-101 following administration of SEL-110) in Pediatric Subjects with Mut Subtype Isolated Methylmalonic Acidemia (MMA)Participants currently recruited/enrolled3-17 YearsNHGRIGenetic Bone
000756-DKPhase II Study of Growth Hormone Inhibition Using Pegvisomant In Severe Insulin ResistanceParticipants currently recruited/enrolled18-65 YearsNIDDKRare Bone
000609-IPilot Study to Assess the Use of JSP191 in Matched Unrelated Donor Transplantation for Chronic Granulomatous Disease (CGD)Participants currently recruited/enrolled4-65 YearsNIAIDRare Bone
000585-CHAn Open-label Safety, Pharmacokinetic, and Efficacy Study of Miglustat for the Treatment of CLN3 Disease in Patients 17 Years of Age and OlderParticipants currently recruited/enrolled17-125 YearsNICHDRare Genetic
000547-HGObservational Study of Advanced Data Analytics in Genetic ConditionsRecruitment has not started0-125 YearsNHGRIRare Genetic
000464-HEvaluation of Clonal Hematopoiesis in Patients with Sickle Cell Disease Receiving Curative TherapiesEnrolling by Invitation4-125 YearsNHLBIGenetic Bone
000387-HThe Natural History of Acquired and Inherited Bone Marrow Failure Syndromes.Participants currently recruited/enrolled2-125 YearsNHLBIRare Bone
000356-CA Phase I/II Trial of BMS-986253 in Myelodysplastic SyndromesParticipants currently recruited/enrolled18-125 YearsNCI Genetic Bone
000324-CPhase 1/2 Dose Escalation Study of CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults with Recurrent or Refractory CD19/CD22-expressing B Cell MalignanciesParticipants currently recruited/enrolled3-35 YearsNCI Genetic Bone
000302-CA Multi-Center Natural History of Urothelial Cancer and Rare Genitourinary Tract MalignanciesParticipants currently recruited/enrolled18-125 YearsNCI Rare Genetic
000137-CHImplications of Maternal 45,X Mosaicism As A Secondary Genomic Finding Following Cell-free DNA Sequencing During Pregnancy: A Deep Phenotype StudyRecruitment has not started18-99 YearsNICHDGenetic Bone
000130-DKUnraveling the Mechanisms Underlying Primary Sclerosing Cholangitis Through a Multidisciplinary, Integrative Research ApproachParticipants currently recruited/enrolled18-125 YearsNIDDKRare Bone
000081-CA Phase 2 Study of Anti-PD-L1 Antibody (Atezolizumab) in Chondrosarcoma and Clear Cell SarcomaCompleted Study; data analyses ongoing2-125 YearsNCI Rare Bone
000046-COmics of Cancer: OncoGenomicsRecruitment has not started0-125 YearsNCI Genetic Bone
000030-CPhase 2 Study of Bintrafusp alfa in Recurrent/Metastatic Olfactory Neuroblastoma (BARON).Participants currently recruited/enrolled18-125 YearsNCI Rare Bone
21-I-0029Natural history, epidemiology and pathogenesis of severe HPV-related diseases (Neptune)Participants currently recruited/enrolled3-125 YearsNIAIDGenetic Bone
21-HG-0020Caregiving Networks Across Disease Context and the Life Course: A Comparative Longitudinal StudyParticipants currently recruited/enrolled18-125 YearsNHGRIRare Genetic
21-C-0032GD2-CAR PERSIST: Production and Engineering of GD2-Targeted, Receptor Modified T Cells (GD2CART) for Osteosarcoma or Neuroblastoma to Increase Systemic Tumor ExposureParticipants currently recruited/enrolled0-35 YearsNCI Genetic Bone
21-C-0021SARC037: A Phase I/II Study to Evaluate the Safety of Trabectedin Administered as a 1-Hour Infusion in Ewing Sarcoma Patients in Combination with Low Dose Irinotecan and 3'-Deoxy-3'-18F Fluorothymidine (18F-FLT) ImagingParticipants currently recruited/enrolled6-125 YearsNCI Genetic Bone
20-I-0088An Open-label Efficacy and Safety Study of Pozelimab in Patients with CD55 deficient Protein-losing Enteropathy (CHAPLE Disease)Participants currently recruited/enrolled3-125 YearsNIAIDRare Genetic
20-HG-0156A Multicenter, Multinational, Randomized, Double-Blind, Placebo-Controlled Study to Assess The Efficacy, Pharmacodynamics, Pharmacokinetics, Safety, and Tolerability of Venglustat in Late-Onset GM2 Gangliosidosis (Tay-Sachs Disease And Sandhoff Disease) No longer recruiting/follow-up only2-125 YearsNHGRIRare Genetic
20-HG-0120Acute Infection in Mitochondrial Disease: An Observational Prospective Natural History Study of Metabolism, Infection and Immunity During the COVID19 PandemicParticipants currently recruited/enrolled0-125 YearsNHGRIRare Genetic
20-HG-0025A Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study to Evaluate the Efficacy of ManNAc in Subjects with GNE MyopathyParticipants currently recruited/enrolled18-125 YearsNHGRIRare Genetic
20-H-0080Red Cell Half Life Determination in Patients with and without Sickle Cell DiseaseCompleted Study; data analyses ongoing18-100 YearsNHLBIGenetic Bone
20-H-0033Early Initiation of Oral Therapy with Cyclosporine and Eltrombopag for Treatment Naive Severe Aplastic Anemia (SAA)Participants currently recruited/enrolled3-125 YearsNHLBIRare Bone
20-CH-0165Androgen Receptor, Implications for Health and Wellbeing: Natural History Study of Individuals with Androgen InsensitivityParticipants currently recruited/enrolled0-99 YearsNICHDRare Bone
20-C-0127A Phase 1 Study of Romidepsin, CC-486 (5-azacitidine), dexamethasone, and lenalidomide (RAdR) for relapsed/refractory T-cell malignanciesParticipants currently recruited/enrolled18-125 YearsNCI Rare Bone
20-C-0107Clinical, Genetic, and Epidemiologic Study of Children and Adults with RASopathiesParticipants currently recruited/enrolled0-125 YearsNCI Genetic Bone
19-H-0111Early Clonal Dynamics During Venetoclax Treatment for Chronic Lymphocytic Leukemia (CLL)Participants currently recruited/enrolled18-125 YearsNHLBIGenetic Bone
19-C-0137A Phase II Study of Ipilimumab, Cabozantinib, and NIvolumab in Rare Genitourinary Cancers (ICONIC)Participants currently recruited/enrolled18-125 YearsNCI Rare Bone
19-C-0104A Phase II Multi-Institutional Trial to Evaluate Prostate Specific Membrane Antigen (PMSA)-Based PET Imaging of High Risk Prostate CancerParticipants currently recruited/enrolled18-125 YearsNCI Genetic Bone
19-C-0082Natural History Study of Children and Adults with ChordomaParticipants currently recruited/enrolled2-125 YearsNCI Rare Bone
19-C-0042A Phase I Study of Moxetumomab Pasudotox-tdfk (Lumoxiti (TM)) and either Rituximab (Rituxan (R)) or Ruxience for Relapsed Hairy Cell LeukemiaNo longer recruiting/follow-up only18-125 YearsNCI Rare Bone
19-C-0025Tissue Acquisition and Genomics Analysis of Breast Cancer and Other Gynecologic MalignanciesEnrolling by Invitation18-125 YearsNCI Genetic Bone
19-C-0016Natural History and Biospecimen Acquisition Study for Children and Adults with Rare Solid TumorsParticipants currently recruited/enrolled0-125 YearsNCI Rare Genetic
18-H-0108Vascular Disease Discovery ProtocolParticipants currently recruited/enrolled2-100 YearsNHLBIRare Genetic
18-CH-0031Clinical and Molecular Characteristics of Primary Aldosteronism in BlacksParticipants currently recruited/enrolled7-70 YearsNICHDGenetic Bone
18-C-0138An Open-Label Phase 2 Study to Evaluate PT2977 for the Treatment of Von Hippel-Lindau Disease-Associated Renal Cell Carcinoma.No longer recruiting/follow-up only18-125 YearsNCI Rare Genetic
18-AR-0081Investigation of the Natural History, Genetics, and Pathophysiology of Systemic Juvenile Idiopathic Arthritis, Adult-Onset Still's Disease and Related Inflammatory ConditionsParticipants currently recruited/enrolled0-125 YearsNIAMSGenetic Bone
17-N-0131Investigating Complex Neurodegenerative Disorders Related to Amyotrophic Lateral Sclerosis and Frontotemporal DementiaParticipants currently recruited/enrolled18-125 YearsNINDSGenetic Bone
17-I-0016Studies of the Natural History, Pathogenesis, and Outcome of Autoinflammatory Diseases (NOMID/CAPS, DIRA, CANDLE, SAVI, NLRC4-MAS, Still's-like Diseases, and Other Undifferentiated Autoinflammatory Diseases)Participants currently recruited/enrolled0-99 YearsNIAIDGenetic Bone
17-H-0121Eltrombopag for Patients with Fanconi AnemiaParticipants currently recruited/enrolled2-125 YearsNHLBIGenetic Bone
17-H-0069Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell DiseaseParticipants currently recruited/enrolled2-125 YearsNHLBIRare Bone
17-CH-0078Setmelanotide (RM-493; Rhythm Pharmaceuticals, Inc.) Phase 2 Open-Label Treatment Trials in Patients with Rare Genetic Disorders of ObesityNo longer recruiting/follow-up only6-100 YearsNICHDRare Genetic
17-C-0149Phase 2 Trial of Pembrolizumab in Relapsed and Refractory Gray-Zone Lymphoma (GZL), Primary Central Nervous System Lymphoma (PCNSL),and Other Extranodal Diffuse Large B-cell LymphomasNo longer recruiting/follow-up only18-125 YearsNCI Rare Bone
17-C-0102Phase II Trial of the Immune Checkpoint Inhibitor Nivolumab in Patients with Recurrent Select Rare CNS CancersParticipants currently recruited/enrolled18-99 YearsNCI Rare Genetic
17-C-0086An Open-label Phase 2 Study to Evaluate PT2385 for the Treatment of Von Hippel-Lindau Disease-Associated Clear Cell Renal Cell CarcinomaNo longer recruiting/follow-up only18-125 YearsNCI Rare Genetic
17-C-0048Anti-CD30 CAR T Cells with Fully-human Binding Domains for Treating CD30-expressing Lymphomas Including Anaplastic Large Cell LymphomasCompleted Study; data analyses ongoing18-73 YearsNCI Genetic Bone
16-HG-0017Genomic Services Research ProgramParticipants currently recruited/enrolled0-125 YearsNHGRIRare Genetic
16-DK-0125Evaluation of Adults with Endocrine-Related ConditionsParticipants currently recruited/enrolled18-100 YearsNIDDKGenetic Bone
16-D-0040Natural History of Craniofacial Anomalies and Developmental Growth VariantsParticipants currently recruited/enrolled2-125 YearsNIDCRRare Genetic
16-CH-0113Evaluation of Children with Endocrine and Metabolic-Related ConditionsParticipants currently recruited/enrolled0-100 YearsNICHDGenetic Bone
16-C-0171Phase I/II Study of Lenalidomide Combined with Modified DA-EPOCH and Rituximab (EPOCH-R2) in Primary Effusion Lymphoma or KSHV-Associated Large Cell LymphomaParticipants currently recruited/enrolled18-125 YearsNCI Rare Bone
15-M-0139Mapping the Genotype, Phenotype, and Natural History of Phelan McDermid SyndromeParticipants currently recruited/enrolled1-125 YearsNIMH Rare Genetic
15-HG-0130Clinical and Genetic Evaluation of Patients with Undiagnosed Disorders Through the Undiagnosed Diseases NetworkParticipants currently recruited/enrolled0-100 YearsNHGRIRare Genetic
15-H-0190Human Biospecimen Procurement and Analysis to Support Translational Research to Identify Genetic Etiology and Disease Mechanism(s) in Rare Genetic Vascular/Cardiovascular DiseasesParticipants currently recruited/enrolled0-125 YearsNHLBIRare Genetic
15-EI-0128The Genetics of Inherited Eye DiseaseParticipants currently recruited/enrolled0-125 YearsNEI Rare Genetic
15-AR-0165Study of the Natural History, Pathogenesis and Outcome of Melorheostosis - a Rare Osteosclerotic DiseaseParticipants currently recruited/enrolled18-90 YearsNIAMSRare Bone
14-I-0206Novel Genetic Disorders of the Immune SystemParticipants currently recruited/enrolled0-99 YearsNIAIDRare Genetic
14-I-0146The Pathogenesis and Genetics of Disseminated or Refractory CoccidioidomycosisParticipants currently recruited/enrolled2-100 YearsNIAIDRare Genetic
14-I-0020Hematopoietic Stem Cell Mobilization in Idiopathic CD4 Lymphocytopenia Patients and Healthy Controls for the Study of T Cell Maturation and Trafficking in Murine ModelsParticipants currently recruited/enrolled18-65 YearsNIAIDRare Bone
14-C-0007Phase II Trial of the Gamma-Secretase Inhibitor Nirogacestat (PF-03084014) in Adults with Desmoid Tumors/Aggressive FibromatosisNo longer recruiting/follow-up only18-125 YearsNCI Rare Genetic
13-C-0006Phase I/II Trial Evaluating the Safety and Efficacy of Ruxolitinib in Patients with Smoldering and Chronic Adult T-cell Leukemia (ATL)Completed Study; data analyses ongoing18-125 YearsNCI Rare Bone
12-N-0095Clinical and Molecular Manifestations of Neuromuscular and Neurogenetic Disorders of ChildhoodParticipants currently recruited/enrolled0-125 YearsNINDSGenetic Bone
12-H-0150Eltrombopag Added to Standard Immunosuppression in Treatment-Naive Severe Aplastic AnemiaParticipants currently recruited/enrolled2-125 YearsNHLBIRare Bone
12-H-0035A Phase II study of Ibrutinib for Patients with Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL) Who Need Therapy and are Older than 65 or have a 17p DeletionNo longer recruiting/follow-up only18-125 YearsNHLBIGenetic Bone
12-C-0193Lymphoid Malignancies and Precursors: Tissue Acquisition ProtocolParticipants currently recruited/enrolled18-125 YearsNCI Genetic Bone
11-I-0007Lentiviral Gene Transfer for Treatment of Children Older Than 2 Years of Age with X-Linked Severe Combined ImmunodeficiencyClinical hold/Recruitment or enrollment suspended2-40 YearsNIAIDGenetic Bone
11-H-0209Male Hormones for Telomere Related DiseasesCompleted Study; data analyses ongoing2-125 YearsNHLBIGenetic Bone
11-H-0046Cross-Sectional Characterization of Idiopathic BronchiectasisCompleted Study; data analyses ongoing18-125 YearsNHLBIRare Genetic
11-C-0220Natural History Study of the KSHV Inflammatory Cytokine Syndrome (KICS) Incorporating Pilot Evaluation of KSHV Targeted TherapiesParticipants currently recruited/enrolled18-125 YearsNCI Genetic Bone
11-C-0136Multi-Institutional Prospective Pilot Study of Lupron to Enhance Lymphocyte Immune Reconstitution Following Allogeneic Bone Marrow Transplantation in Post-Pubertal Children and Adults with Molecular Imaging EvaluationCompleted Study; data analyses ongoing2-55 YearsNCI Genetic Bone
11-C-0034DICER1-Related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History StudyParticipants currently recruited/enrolled0-125 YearsNCI Rare Genetic
10-HG-0065Whole Genome Medical Sequencing for Gene DiscoveryParticipants currently recruited/enrolled0-125 YearsNHGRIRare Genetic
10-C-0174Related and Unrelated Donor Hematopoietic Stem Cell Transplant for DOCK8 DeficiencyParticipants currently recruited/enrolled4-125 YearsNCI Genetic Bone
10-C-0054Administration of Anti-CD19-Chimeric-Antigen-Receptor-Transduced T Cells from the Original Transplant Donor to Patients with Recurrent or Persistent B-Cell Malignancies After Allogeneic Stem Cell TransplantationNo longer recruiting/follow-up only18-75 YearsNCI Genetic Bone
09-I-0200A Phase I Study of MozobilTM in the Treatment of Patients with WHIMSParticipants currently recruited/enrolled18-75 YearsNIAIDGenetic Bone
09-I-0184Studies in the Pathogenesis of Systemic Capillary Leak SyndromeParticipants currently recruited/enrolled0-125 YearsNIAIDGenetic Bone
09-I-0086Screening Protocol for Genetic Diseases of Allergic InflammationParticipants currently recruited/enrolled0-99 YearsNIAIDRare Genetic
08-I-0184Studies in the Pathogenesis of AnaphylaxisParticipants currently recruited/enrolled13-75 YearsNIAIDRare Bone
08-C-0079Natural History Study and Longitudinal Assessment of Children, Adolescents, and Adults with Neurofibromatosis Type 1No longer recruiting/follow-up only0-125 YearsNCI Genetic Bone
07-H-0113Procurement and Analysis of Blood, Bone Marrow, and Buccal Mucosa Samples from Healthy Volunteers to Support Clinical and Translational Research Projects in the NHLBIParticipants currently recruited/enrolled8-125 YearsNHLBIGenetic Bone
07-DK-0077Study of the Phenotype of Overweight and Obese AdultsParticipants currently recruited/enrolled18-100 YearsNIDDKGenetic Bone
06-CH-0186Evaluation of Biochemical Markers and Clinical Investigation of Niemann-Pick Disease, Type CParticipants currently recruited/enrolled0-125 YearsNICHDGenetic Bone
06-CH-0011Natural History Study of Patients with Excess AndrogenParticipants currently recruited/enrolled0-99 YearsNICHDGenetic Bone
06-C-0150A Phase II Clinical Trial of Anti-Tac(Fv)-PE38 (LMB-2) Immunotoxin for CD25 Positive Hairy Cell LeukemiaNo longer recruiting/follow-up only18-125 YearsNCI Genetic Bone
05-H-0242A Pilot Study of Alemtuzumab (Campath) in Patients with Relapsed or Refractory Severe Aplastic AnemiaCompleted Study; data analyses ongoing2-110 YearsNHLBIRare Bone
05-CC-0041Endothelial Cell Dysfunction in Pulmonary Arterial Hypertension: Biomarkers, Mechanisms of Disease and Novel Therapeutic TargetsCompleted Study; data analyses ongoing18-125 YearsCC Rare Genetic
05-C-0152Variation in Gene Expression in Neurofibromatosis Type 1Completed Study; data analyses ongoing2-100 YearsNCI Rare Genetic
04-N-0056The Neural Immune Mechanisms and Genetic Influences on Chronic Pelvic Pain in Women with EndometriosisCompleted Study; data analyses ongoing18-50 YearsNINDSGenetic Bone
04-I-0286A Longitudinal Study of Familial Hypereosinophilia (FE): Natural History and Markers of Disease ProgressionParticipants currently recruited/enrolled1-100 YearsNIAIDGenetic Bone
04-I-0266Collection of Data and Samples from Healthy Donors for Use in Translational ResearchParticipants currently recruited/enrolled18-65 YearsNIAIDGenetic Bone
04-CH-0077Investigations of Bone-Related Connective Tissue DisordersCompleted Study; data analyses ongoing0-70 YearsNICHDGenetic Bone
04-C-0275Targeted Oncolytic Virotherapy and Natural History Study of KSHV-Associated Multicentric Castleman's Disease with Laboratory and Clinical Correlates of Disease ActivityNo longer recruiting/follow-up only18-125 YearsNCI Rare Bone
03-AR-0173Studies of Natural History, Pathogenesis, and Outcomes in Autoimmune and Inflammatory Diseases Including Juvenile DermatomyositisParticipants currently recruited/enrolled2-125 YearsNIAMSGenetic Bone
03-AR-0131Genetic Determinants of Ankylosing Spondylitis Severity - Longitudinal StudyCompleted Study; data analyses ongoing18-125 YearsNIAMSGenetic Bone
02-I-0277Regulation of the Proliferation and Survival of Normal and Neoplastic Human Mast CellsParticipants currently recruited/enrolled0-80 YearsNIAIDGenetic Bone
02-I-0147Genetic Studies of Chronic Active Epstein-Barr Virus InfectionParticipants currently recruited/enrolled1-125 YearsNIAIDRare Genetic
02-CH-0311Investigations into Inborn Errors of Cholesterol Synthesis and Related DisordersParticipants currently recruited/enrolled0-125 YearsNICHDRare Genetic
02-C-0210Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of Blood and Lymph Node MalignancyParticipants currently recruited/enrolled0-125 YearsNCI Genetic Bone
02-C-0159Birt-Hogg-Dub(SqrRoot)(Copyright) Syndrome: Characterization of the FLCN Disease Gene and Predisposition to Renal Cancer, Cutaneous Fibrofolliculoma and Pulmonary CystsParticipants currently recruited/enrolled2-125 YearsNCI Rare Genetic
02-C-0052Etiologic Investigation of Cancer Susceptibility in Inherited Bone Marrow Failure Syndromes: A Natural History StudyParticipants currently recruited/enrolled0-125 YearsNCI Genetic Bone
01-HG-0109Natural History Study of the Clinical and Molecular Manifestations of Smith-Magenis Syndrome (SMS)No longer recruiting/follow-up only0-125 YearsNHGRIRare Genetic
00-N-0043Clinical and Molecular Manifestations of Inherited Neurological DisordersParticipants currently recruited/enrolled2-125 YearsNINDSRare Genetic
00-I-0159Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection Syndrome (HIES)Participants currently recruited/enrolled0-125 YearsNIAIDGenetic Bone
00-HG-0209Molecular and Clinical Studies of Primary Immunodeficiency DiseasesNo longer recruiting/follow-up only3-125 YearsNHGRIGenetic Bone
00-H-0051Cutaneous Tumorigenesis in Patients with Tuberous SclerosisParticipants currently recruited/enrolled18-90 YearsNHLBIRare Genetic
00-CH-0136A Trial of Pamidronate in Children with Osteogenesis ImperfectaCompleted Study; data analyses ongoing2-17 YearsNICHDGenetic Bone
99-C-0099Examination of Clinical and Laboratory Abnormalities in Patients with Defective DNA Repair: Xeroderma Pigmentosum, Cockayne Syndrome, or TrichothiodystrophyParticipants currently recruited/enrolled0-125 YearsNCI Rare Genetic
98-N-0047Immuno-Virological Evaluation of Human T Cell Leukemia Virus Type-1 Associated Myelopathy (HAM/TSP)Participants currently recruited/enrolled18-125 YearsNINDSRare Genetic
97-HG-0192Genetic Studies in the Amish and MennonitesCompleted Study; data analyses ongoing18-125 YearsNHGRIRare Genetic
97-CH-0064Evaluation and Intervention for Ambulation, Growth, and Basilar Invagination in Osteogenesis ImperfectaCompleted Study; data analyses ongoing0-10 YearsNICHDGenetic Bone
96-I-0052A Comprehensive Clinical, Microbiological and Immunological Assessment of Patients with Suspected Post Treatment Lyme Disease Syndrome and Selected Control PopulationsParticipants currently recruited/enrolled13-125 YearsNIAIDGenetic Bone
94-I-0073Recruitment and Apheresis Collection of Peripheral Blood Hematopoietic Stem Cells, Mononuclear Cells and GranulocytesParticipants currently recruited/enrolled18-70 YearsNIAIDGenetic Bone
94-HG-0132The Phenotype and Etiology of Proteus SyndromeParticipants currently recruited/enrolled0-125 YearsNHGRIRare Genetic
94-DK-0127Pathogenesis of GlomerulosclerosisCompleted Study; data analyses ongoing2-125 YearsNIDDKRare Genetic
94-AR-0066Studies of the Pathogenesis and Natural History of Systemic Lupus Erythematosus (SLE)Participants currently recruited/enrolled9-125 YearsNIAMSGenetic Bone
93-I-0063Study of the Immunopathogenesis, Natural History, and Genetics of Autoimmune Lymphoproliferative Syndrome (ALPS) Associated with an Expansion of CD4-8-/TCR alpha/beta+ T CellsParticipants currently recruited/enrolled0-99 YearsNIAIDRare Genetic
76-HG-0238Diagnosis and Treatment of Patients with Inborn Errors of Metabolism or Other Genetic DisordersParticipants currently recruited/enrolled0-125 YearsNHGRIRare Genetic
001109-CDefining the Natural History of Squamous Cell Carcinoma in Fanconi AnemiaParticipants currently recruited/enrolled8-125 YearsNCI Bone
001074-CHCharacterization of Dysmorphology in Subjects with Creatine Transporter DeficiencyParticipants currently recruited/enrolled2-40 YearsNICHDGenetic
001061-HObservational Study Investigating the Mechanistic Effects of Mitapivat in Subjects with Sickle Cell DiseaseEnrolling by Invitation16-125 YearsNHLBIBone
001043-IEvaluating the Genetics and Immunology of Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis (PFAPA) Syndrome and Other Tonsil DisordersRecruitment has not started0-125 YearsNIAIDGenetic
000977-IPhase I/II Study using Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Granulomatous Disease with an Alemtuzumab, Busulfan and TBI-based Conditioning Regimen Combined with Cytokine (IL-6, +/- IFN-gamma) AntagonistsParticipants currently recruited/enrolled4-65 YearsNIAIDBone
000975-CCollection of Blood, Bone Marrow, Skin, Saliva, and Stool Samples from Healthy Volunteers Used for Comparative Analysis of Myeloid MalignanciesParticipants currently recruited/enrolled18-125 YearsNCI Bone
000958-CProspective Procurement of Tumor Tissue to Identify Novel Therapeutic Targets and Study the Tumor MicroenvironmentEnrolling by Invitation18-125 YearsNCI Genetic
000954-CA Phase 1/2 Single Arm Open-Label Clinical Trial of TC-510 In Patients with Advanced Mesothelin-Expressing CancerParticipants currently recruited/enrolled18-125 YearsNCI Genetic
000912-HGGenetic and Social Network Correlates of Rheumatoid Arthritis Outcomes in Hispanic Populations: A Prospective StudyParticipants currently recruited/enrolled18-125 YearsNHGRIGenetic
000906-IA Phase 2 Randomized, Double-Blinded Cross-Over Design Study of the Early Metabolic Effects of Dolutegravir or Tenofovir Alefenamide in Healthy VolunteersRecruitment has not started18-55 YearsNIAIDBone
000894-ARNatural History of Inflammatory Muscle DiseasesRecruitment has not started12-125 YearsNIAMSGenetic
000871-CCMediterranean-like Unprocessed (CLEAN-MED) Diet Intervention Study of the Gut Microbiome of Healthy AdultsParticipants currently recruited/enrolled18-60 YearsCC Genetic
000867-CCHumanitarian Use Device (HUD) Protocol for Use of Miltenyi CliniMACS (Registered Trademark) CD34 Reagent System in AMLParticipants currently recruited/enrolled0-125 YearsCC Bone
000829-HControls and Healthy Vasculature InitiativeParticipants currently recruited/enrolled18-125 YearsNHLBIGenetic
000798-DA Phase 2 Study of Burosumab for Fibroblast Growth Factor-23 Mediated Hypophosphatemia in Fibrous DysplasiaParticipants currently recruited/enrolled1-125 YearsNIDCRBone
000792-CA Multicenter Study to Evaluate Next-Generation Sequencing (NGS) Testing and Monitoring of B-Cell Recovery to Guide Management Following Chimeric Antigen Receptor T-cell (CART) Induced Remission in Children and Young Adults with B Lineage Acute LymphoblaRecruitment has not started1-25 YearsNCI Bone
000780-DA Phase 2 Study of Denosumab for Prevention of Skeletal Disease Progression in Children with Fibrous DysplasiaParticipants currently recruited/enrolled4-14 YearsNIDCRBone
000732-CA Long-Term Follow-Up Study of Patients Who Received VOR33Recruitment has not started18-125 YearsNCI Bone
000731-CA First-In-Human, Open-Label, Multicenter Study of VOR33 in Patients with Acute Myeloid Leukemia who are at High-Risk for Leukemia Relapse following Hematopoietic Cell TransplantationParticipants currently recruited/enrolled18-70 YearsNCI Bone
000726-CA Randomized Phase 2 Study of Atezolizumab with or without Selinexor in Alveolar Soft Part Sarcoma (AXIOM)Participants currently recruited/enrolled18-125 YearsNCI Rare
000697-HU01 Cooperative Assessment of Late Effects for SCD Curative Therapies (COALESCE)Participants currently recruited/enrolled18-65 YearsNHLBIBone
000696-CA Phase III, Multicenter, International Study with a Parallel, Randomized, Double-blind, Placebo-controlled, 2 Arm Design to Assess the Efficacy and Safety of Selumetinib in Adult Participants with NF1 who have Symptomatic, Inoperable Plexiform NeurofibrParticipants currently recruited/enrolled18-120 YearsNCI Genetic
000692-CRapid Analysis and Response Evaluation of Combination Anti-Neoplastic Agents in Rare Tumors (RARE CANCER) Trial: RARE 2 Talazoparib and TemozolomideParticipants currently recruited/enrolled12-125 YearsNCI Rare
000688-ILongitudinal Observations of Vaccine Responses to SARS-CoV-2 and other Emerging Infectious DiseasesParticipants currently recruited/enrolled18-125 YearsNIAIDGenetic
000686-CHIntrathecal 2-Hydroxypropyl-Beta-Cyclodextrin for Neurological Decline in Patients with Niemann-Pick Disease Type C1Participants currently recruited/enrolled18-125 YearsNICHDRare
000665-DKA Randomized Double-Blind Placebo-Controlled Study of the LEPR Agonist Antibody REGN4461 for the Treatment of Metabolic Abnormalities in Patients with Familial Partial LipodystrophyParticipants currently recruited/enrolled18-125 YearsNIDDKBone
000661-CComprehensive Molecular and Clinical Evaluation of Pediatric and Adult Myelodysplastic Syndromes (MDS)Participants currently recruited/enrolled0-125 YearsNCI Bone
000633-CPhase 1/2 Study of VIP152, Venetoclax, and Prednisone (VVIP) in Relapsed/Refractory Lymphoid MalignanciesParticipants currently recruited/enrolled18-125 YearsNCI Bone
000631-CInvestigation of the Cognitive Aftereffects of Neurotoxicity in Children and Young Adults with Relapsed/Refractory Hematologic Malignancies who Receive CAR T-cell TherapyRecruitment has not started5-125 YearsNCI Genetic
000628-CA Study of Prospective Monitoring of Subjects with Biochemically Recurrent Prostate Cancer Using 18F-DCFPyLParticipants currently recruited/enrolled18-125 YearsNCI Bone
000613-CPhase I/II Trial to Determine the Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination with Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis after Reduced Intensity Conditioning and Peripheral Blood StParticipants currently recruited/enrolled12-125 YearsNCI Bone
000596-CPhase II Study of Olaparib in Subjects with Advanced Pancreatic Acinar Cell CarcinomaParticipants currently recruited/enrolled18-125 YearsNCI Rare
000577-HGGenomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African Americans Study (GENEFORECAST): Prospective COVID-19 Natural History StudyParticipants currently recruited/enrolled21-125 YearsNHGRIGenetic
000560-NData Collection of Standard Care of Patients in the EMG SectionParticipants currently recruited/enrolled18-125 YearsNINDSRare
000539-HAddition of JSP191 (c-kit antibody) to Non-myeloablative Hematopoietic Cell Transplantation For Sickle Cell Disease and Beta-ThalassemiaParticipants currently recruited/enrolled4-100 YearsNHLBIBone
000518-CCObservational Study of Dietary Intake and Dietary Behaviors in Adults with Sickle Cell DiseaseParticipants currently recruited/enrolled18-125 YearsCC Genetic
000516-CPhase 1 Study of Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (VIPOR) for Diffuse Large B-cell Lymphoma involving the Central Nervous SystemParticipants currently recruited/enrolled18-125 YearsNCI Bone
000491-CTissue Procurement and Natural History Study of Neuroendocrine Neoplasms (NENs) Including Adrenocortical Carcinoma (ACC)Participants currently recruited/enrolled18-125 YearsNCI Rare
000489-CPhase I/II Study Using Prophylactic Donor Lymphocyte Infusion Early Post-Transplant After Allogeneic Hematopoietic Cell Transplantation Using Post-Transplantation Cyclophosphamide for High-Risk Hematologic MalignanciesClinical hold/Recruitment or enrollment suspended12-125 YearsNCI Bone
000487-CHNatural History Investigation into Biochemical and Phenotypical Aspects of Smith-Lemli-Opitz Syndrome and Related Disorders of Cholesterol MetabolismParticipants currently recruited/enrolled0-125 YearsNICHDGenetic
000486-CA Phase 1 Trial of the ATR Inhibitor BAY 1895344 in Combination with Cisplatin and with Cisplatin Plus Gemcitabine in Advanced Solid Tumors with an Emphasis on Urothelial CarcinomaParticipants currently recruited/enrolled18-125 YearsNCI Genetic
000478-CA Phase I/II Trial of Allogeneic Reduced-Intensity, HLA-Haploidentical Bone Marrow Transplantation Followed by GVHD Prophylaxis with Cyclophosphamide, Bortezomib and Maraviroc for Hematologic Malignancies in People Living with HIV (PLWH)Participants currently recruited/enrolled12-125 YearsNCI Bone
000475-CPhase 2 Study of Rogaratinib (BAY 1163877) in the Treatment of Patients with Sarcoma Harboring Alterations in Fibroblast Growth Factor Receptor (FGFR) 1-4 and SDH-deficient Gastrointestinal Stromal Tumor (GIST)Participants currently recruited/enrolled18-125 YearsNCI Bone
000428-NAn Observational Study to Assess Clinical, Molecular and Imaging Biomarkers in Spinal and Bulbar Muscular Atrophy (SBMA)Participants currently recruited/enrolled18-125 YearsNINDSBone
000417-CCCharacterization of the Nociception Phenotype in Individuals with Intellectual DisabilityClinical hold/Recruitment or enrollment suspended8-30 YearsCC Bone
000414-CHPilot Study of an Optic-to-Audio Device in a Pediatric Cohort with CLN3-related Conditions or Low VisionParticipants currently recruited/enrolled6-18 YearsNICHDGenetic
000413-HNatural History study of CADASILParticipants currently recruited/enrolled18-100 YearsNHLBIGenetic
000404-CA Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Subjects with VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) SyndromeParticipants currently recruited/enrolled18-75 YearsNCI Bone
000359-CPhase I/II study to reduce post-transplantation cyclophosphamide dosing for older or unfit patients undergoing bone marrow transplantation for hematologic malignanciesParticipants currently recruited/enrolled12-85 YearsNCI Bone
000350-DUse of Clear Aligners for the Treatment of Dental Malocclusion In Individuals with Osteogenesis Imperfecta Types III and IVParticipants currently recruited/enrolled12-40 YearsNIDCRBone
000344-DKNatural History Study of Parathyroid DisordersParticipants currently recruited/enrolled0-125 YearsNIDDKBone
000343-HDetection of T cell Somatic Mutations in Bone Marrow Failure Using Whole Exome or Targeted SequencingEnrolling by Invitation18-125 YearsNHLBIBone
000337-CNatural History Study of KSHV-Associated Multicentric Castleman's DiseaseParticipants currently recruited/enrolled18-125 YearsNCI Bone
000328-CBicalutamide Implants (Biolen ) with Radiation Therapy in Patients with Localized Prostate CancerParticipants currently recruited/enrolled18-125 YearsNCI Bone
000326-HA Phase 1, Dose Escalation, Safety and Tolerability Study of NX- 2127, a Bruton's Tyrosine Kinase (BTK) Degrader, in Adults with Relapsed/Refractory B-cell MalignanciesParticipants currently recruited/enrolled18-125 YearsNHLBIBone
000320-IRandomized, Double-Blinded, Placebo-Controlled, Phase 1 Study of the Safety and Immunogenicity of BPL-1357, A BPL-Inactivated, Whole-Virus, Universal Influenza VaccineParticipants currently recruited/enrolled18-55 YearsNIAIDGenetic
000305-CExploratory Phase II Study of LAnreotide in Unresectable or Metastatic Pheochromocytoma / PARAgangliomaParticipants currently recruited/enrolled18-125 YearsNCI Rare
000303-CA Prospective, Multi-Institutional Phase II Trial Evaluating Temozolomide Vs. Temozolomide and Olaparib For Advanced Pheochromocytoma And ParagangliomaParticipants currently recruited/enrolled18-125 YearsNCI Rare
000297-CHA Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Crinecerfont (NBI-74788) in Adult Subjects with Classic Congenital Adrenal Hyperplasia, Followed by Open-Label TreatmentParticipants currently recruited/enrolled18-125 YearsNICHDBone
000288-CA Phase II, Open-Label, Single-Arm Study of Berzosertib (M6620) in Combination with Topotecan in Participants with Relapsed Platinum-Resistant Small-Cell Lung CancerCompleted Study; data analyses ongoing18-125 YearsNCI Bone
000281-IPilot Assessment To Find Evidence of Gastric Motility Abnormalities in Eosinophilic Gastric Disorders (OAT-FEED)Participants currently recruited/enrolled18-59 YearsNIAIDRare
000277-CImaging and Biopsy of HIV-Infected Individuals Undergoing Analytic Treatment InterruptionParticipants currently recruited/enrolled18-125 YearsNCI Bone
000272-HDefining the Genetic Etiology of Suppurative Lung Disease in Children and AdultsParticipants currently recruited/enrolled5-45 YearsNHLBIGenetic
000254-CA Phase II Trial of the Superenhancer Inhibitor Minnelide in Advanced Refractory Adenosquamous Carcinoma of the Pancreas (ASCP)Participants currently recruited/enrolled18-125 YearsNCI Rare
000236-IA Phase 1 Study of Empagliflozin as Treatment for Severe Congenital Neutropenia Due to G6PC3 DeficiencyParticipants currently recruited/enrolled18-125 YearsNIAIDBone
000206-CHEndometrial Basis for Infertility in Women with Recurrent Implantation Failure and Pregnancy LossParticipants currently recruited/enrolled18-42 YearsNICHDGenetic
000201-IPediatric SARS-CoV-2 and MIS-C Long-term Follow-upParticipants currently recruited/enrolled0-21 YearsNIAIDGenetic
000194-CA Phase I Trial of ProAgio, an anti- alpha-v-beta3 Integrin Cytotoxin, for Previously Treated Advanced Pancreatic Cancer and Other Solid Tumor MalignanciesParticipants currently recruited/enrolled18-125 YearsNCI Bone
000193-CPhase 1 Study of Copanlisib with Dose-adjusted EPOCH-R in Relapsed and Refractory Burkitt Lymphoma and other High-Grade B-cell LymphomasClinical hold/Recruitment or enrollment suspended18-125 YearsNCI Bone
000186-IPart B- Phase I/II, Non-randomized, Multicenter, Open-label Study of G1XCGD (Lentiviral Vector Transduced CD34+ Cells) in Patients with X-Linked Chronic Granulomatous DiseaseClinical hold/Recruitment or enrollment suspended3-12 YearsNIAIDBone
000124-CA Phase 2 Study of the MEK inhibitor Trametinib (IND #119346, NSC# 763093) in Children with Relapsed or Refractory Juvenile Myelomonocytic LeukemiaRecruitment has not started2-21 YearsNCI Bone
000114-CA Phase II Study Evaluating T-Cell Clonality After Stereotactic Body Radiation Therapy Alone and in Combination with the Immunocytokine M9241 in Localized High and Intermediate Risk Prostate Cancer Treated with Androgen Deprivation TherapyParticipants currently recruited/enrolled18-125 YearsNCI Bone
000092-CPhase 1/2 study of Vincristine and Temozolomide in Combination with PEN-866 for Adolescents and Young Adults with Relapsed or Refractory Solid TumorsRecruitment has not started12-39 YearsNCI Genetic
000079-DKThe Role of 68-Gallium-DOTATATE-PET/CT in the Imaging of Metastatic Thyroid CancerParticipants currently recruited/enrolled18-125 YearsNIDDKBone
000051-NNIH Investigative Deep Phenotyping Study of Gulf War Veteran Health (Project NIH IN-DEPTH)Participants currently recruited/enrolled48-70 YearsNINDSBone
000049-HEvaluation of the Safety,Tolerability, Pharmacokinetics, and Pharmacodynamics of Long-term Mitapivat Dosing in Subjects with Stable Sickle Cell Disease: An Extension of a Phase I Pilot Study of MitapivatNo longer recruiting/follow-up only18-70 YearsNHLBIBone
000048-CA Multi-Center Natural History Study of Precision-Based Genomics in Prostate CancerParticipants currently recruited/enrolled18-125 YearsNCI Genetic
22-C-0005Phase I Dose Escalation and Expansion Study of Tazemetostat in Combination with Topotecan and Pembrolizumab in Recurrent Small Cell Lung CancerParticipants currently recruited/enrolled18-125 YearsNCI Genetic
21-N-0016Phase I/II Study of Teriflunomide in HTLV-1 Associated Myelopathy/Tropical Spastic ParaparesisParticipants currently recruited/enrolled18-125 YearsNINDSRare
21-I-0003A Phase 1/2 Study to Evaluate the Safety, Tolerability and Efficacy, of JSP191 for Hematopoietic Cell Transplantation Conditioning to Achieve Engraftment and Immune Reconstitution in Subjects with SCIDParticipants currently recruited/enrolled3-125 YearsNIAIDBone
21-C-0026A Phase I/II Study of Abemaciclib in Patients with HIV-associated and HIV-negative Kaposi SarcomaParticipants currently recruited/enrolled18-125 YearsNCI Bone
21-C-0024A Phase 2 Adaptive Study of Subcutaneous Daratumumab, Once Weekly Carfilzomib, and Dexamethasone (DKd) in Patients with High-Risk Smoldering Multiple MyelomaParticipants currently recruited/enrolled18-125 YearsNCI Bone
21-C-0022A Phase 2 Single Arm Open-Label Clinical Trial of ADP-A2M4 SPEAR(TM) T Cells in Subjects with Advanced Synovial Sarcoma or Myxoid/Round Cell LiposarcomaParticipants currently recruited/enrolled10-75 YearsNCI Bone
21-C-0014Phase 1 Study of Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid in Combination with Polatuzumab (ViPOR-P) in Relapsed/Refractory B-cell LymphomaParticipants currently recruited/enrolled18-125 YearsNCI Bone
21-C-0013A Phase I/II Study of Adjuvant PRGN-2012 in Adult Patients with Recurrent Respiratory PapillomatosisParticipants currently recruited/enrolled18-125 YearsNCI Rare
21-C-0011A Phase I/II Study of the Cyclin-Dependent Kinase(CDK)4/6 Inhibitor Abemaciclib for Neurofibromatosis Type 1 (NF1) Related Atypical NeurofibromasParticipants currently recruited/enrolled12-125 YearsNCI Genetic
21-C-0009A Natural History Study of Children and Adults with Olfactory NeuroblastomaParticipants currently recruited/enrolled3-125 YearsNCI Rare
21-C-0007A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon CancersParticipants currently recruited/enrolled18-125 YearsNCI Bone
21-C-0001A Phase I/II Study of M9241 in Combination with Docetaxel in Adults with Metastatic Castration Sensitive and Castration Resistant Prostate CancerParticipants currently recruited/enrolled18-125 YearsNCI Bone
20-I-0037Matched Related and Unrelated Donor Stem Cell Transplantation for Severe Combined Immune Deficiency (SCID): Busulfan-based Conditioning with h-ATG, Radiation, and SirolimusEnrolling by Invitation3-40 YearsNIAIDBone
20-I-0002Pilot Study of Mepolizumab in Episodic Angioedema with EosinophiliaCompleted Study; data analyses ongoing18-125 YearsNIAIDBone
20-HG-0147An Observational Study of the Developing Brain, Impulsivity and Compulsivity.Participants currently recruited/enrolled6-80 YearsNHGRIGenetic
20-HG-0090Genetics of COVID-19 Susceptibility and ManifestationsClinical hold/Recruitment or enrollment suspended0-125 YearsNHGRIGenetic
20-HG-0034A Multi-Cohort Phase 2 Dose-Escalation Study of MK-7075 (Miransertib) in Proteus SyndromeParticipants currently recruited/enrolled3-125 YearsNHGRIRare
20-H-0158Natural History Study: Gene First Approach to Connective Tissue DiseaseParticipants currently recruited/enrolled2-100 YearsNHLBIBone
20-H-0141Long-term Follow-up of Subjects With Sickle Cell Disease Treated With Ex Vivo Gene Therapy Using Autologous Hematopoietic Stem Cells Transduced With a Lentiviral VectorEnrolling by Invitation18-125 YearsNHLBIBone
20-H-0049NHLBI DIR Cardiovascular Branch PK Papyrus Covered Stent Ethics Oversight of Humanitarian Use Device for Treatment of Acute Perforations of Native Coronary Arteries and Coronary Bypass Grafts in Vessels 2.5 to 5.0 mm in DiameterEnrolling by Invitation18-125 YearsNHLBIRare
20-H-0021Treatment of Refractory Diamond-Blackfan Anemia with EltrombopagNo longer recruiting/follow-up only2-125 YearsNHLBIBone
20-H-0016Duvelisib for Ibrutinib-Resistant Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)Completed Study; data analyses ongoing18-125 YearsNHLBIBone
20-EI-0163Oral Metformin for Treatment of ABCA4 RetinopathyParticipants currently recruited/enrolled12-125 YearsNEI Genetic
20-DK-0168LYNC-LD Prospective Multicenter Natural History Study of Lipodystrophy Syndromes to Determine Prevalence, Incidence and Predictors of Diabetes and Severe Hypertriglyceridemia, and their Complications.Participants currently recruited/enrolled3-125 YearsNIDDKRare
20-DK-0079A Randomized, Double-Blinded, Placebo-Controlled Study of REGN4661, A Leptin Receptor Agonist Antibody, In Patients with Generalized LipodystrophyNo longer recruiting/follow-up only12-125 YearsNIDDKRare
20-D-0122A Phase IIb, Open-label Dose-ranging Study Evaluating the Safety, Tolerability, Pharmacodynamics and Pharmacokinetics, and Efficacy of CLTX-305 (encaleret) in Autosomal Dominant Hypocalcemia Type 1 (ADH1)No longer recruiting/follow-up only16-125 YearsNIDCRBone
20-CH-0126Data Collection Study of Pediatric and Adolescent Gynecology ConditionsParticipants currently recruited/enrolled0-125 YearsNICHDGenetic
20-C-0167Close Assessment and Testing for Chronic Graft-vs-Host Disease (CATCH Study)Participants currently recruited/enrolled18-125 YearsNCI Bone
20-C-0162A Phase 1 Study of Venetoclax with Obinutuzumab and Magrolimab (VENOM) in Relapsed and Refractory Indolent B-cell MalignanciesParticipants currently recruited/enrolled18-125 YearsNCI Bone
20-C-0161Prospective Study of Surgery in Gastrointestinal Stromal Tumors (GISTs) for Treatment, Tumor Modeling, and Genomic AnalysisParticipants currently recruited/enrolled6-125 YearsNCI Genetic
20-C-0121Rapid Analysis and Response Evaluation of Combination Anti-Neoplastic Agents in Rare Tumors (RARE CANCER) Trial: RARE 1 Nilotinib and PaclitaxelParticipants currently recruited/enrolled18-125 YearsNCI Rare
20-C-0106Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients with BAP1 Tumor Predisposition SyndromeParticipants currently recruited/enrolled30-125 YearsNCI Genetic
20-C-0104Phase I/II Trial of HPV Vaccine PRGN-2009 Alone or in Combination with Anti-PD-L1/TGF-Beta Trap (M7824) in Subjects with HPV Positive CancersParticipants currently recruited/enrolled18-125 YearsNCI Bone
20-C-0076Phase 2 Trial of Encorafenib plus Binimetinib for Patients with BRAF V600 Mutated Relapsed/Refractory HCLParticipants currently recruited/enrolled18-125 YearsNCI Bone
20-C-0075Phase 2 Trial for Binimetinib for Patients with Relapsed/Refractory BRAF Wild Type Hairy Cell Leukemia and VariantParticipants currently recruited/enrolled18-125 YearsNCI Bone
20-C-0070A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Patients with Inborn Errors of ImmunityParticipants currently recruited/enrolled4-69 YearsNCI Bone
20-C-0069A First-In-Human Phase I Single-Agent Dose-Escalation, Food Effect and Dose Expansion Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System NeoplasmsParticipants currently recruited/enrolled18-125 YearsNCI Rare
20-C-0061Phase I/II study of NHS-IL12 Monotherapy and in Combination with M7824 in Advanced Kaposi SarcomaParticipants currently recruited/enrolled18-125 YearsNCI Bone
20-C-0058A Study of Front Line Ibrutinib for Newly Diagnosed Chronic Graft-Versus-Host DiseaseParticipants currently recruited/enrolled18-125 YearsNCI Bone
20-C-0041Protocol for a Research Database for Hematopoietic Cell Transplantation, Other Cellular Therapies and Marrow Toxic InjuriesEnrolling by Invitation1-125 YearsNCI Bone
20-C-0011Phase 1 Study of Recombinant Human IL-15 (rhIL-15) and Mogamulizumab for Patients with Refractory or Relapsed Adult T-Cell Leukemia and Mycosis Fungoides/Sezary SyndromeCompleted Study; data analyses ongoing18-125 YearsNCI Bone
20-C-0010Phase II Trial of Radium-223 in Biochemically Recurrent Prostate CancerParticipants currently recruited/enrolled18-125 YearsNCI Bone
20-C-0006A National Translational Science Network of Precision-based Immunotherapy for Primary Liver Cancer (PLC)Participants currently recruited/enrolled18-125 YearsNCI Genetic
19-N-0124Anakinra for the Treatment of Chronically Inflamed White Matter Lesions in Multiple SclerosisParticipants currently recruited/enrolled18-120 YearsNINDSBone
19-M-0054Mapping the Phenotype in Adults with Phelan-McDermid SyndromeCompleted Study; data analyses ongoing0-125 YearsNIMH Genetic
19-I-0133Paradoxical Tuberculosis Reactions in Patients without HIV InfectionParticipants currently recruited/enrolled18-125 YearsNIAIDGenetic
19-I-0080Haploidentical Transplant for Patients with Chronic Granulomatous Disease (CGD) using Alemtuzumab, Busulfan and TBI with Post-Transplant CyclophosphamideParticipants currently recruited/enrolled4-65 YearsNIAIDBone
19-I-0027A Phase 2 Randomized Double-Blinded Placebo-Controlled Study to Evaluate the Safety and Efficacy of Subcutaneous Sarilumab in Improving the Quality of Life in Subjects with Indolent Systemic MastocytosisParticipants currently recruited/enrolled18-75 YearsNIAIDBone
19-I-0015Phase 1/2 Randomized, Double-Blind, Placebo-Controlled Study of Safety and Efficacy of Abatacept for Treating Chronic Cytopenia in Cytotoxic T-lymphocyte Antigen 4 (CTLA4) HaploinsufficiencyParticipants currently recruited/enrolled8-65 YearsNIAIDBone
19-HG-0101A Phase 1/2 Study of Intravenous Gene Transfer with an AAV9 Vector Expressing Human Beta-galactosidase in Type I and Type II GM1 GangliosidosisNo longer recruiting/follow-up only0-12 YearsNHGRIBone
19-HG-0092New Approaches for Empowering Studies of Asthma in Populations of African DescentCompleted Study; data analyses ongoing18-125 YearsNHGRIGenetic
19-H-0139Investigation of the Natural Progression of Clonal Hematopoiesis of Indeterminate Potential and Clonal Cytopenia of Undetermined Significance.Participants currently recruited/enrolled18-125 YearsNHLBIBone
19-H-0118Repeat Peripheral Blood Stem Cell Transplantation for Patients with Sickle Cell Disease or Beta-Thalassemia and Falling Donor Myeloid Chimerism LevelsParticipants currently recruited/enrolled2-80 YearsNHLBIBone
19-DK-0066The Evaluation and Management of Endocrine-Related Conditions and PhysiologyParticipants currently recruited/enrolled18-90 YearsNIDDKGenetic
19-CH-0051Long-Term Follow-UP of Survivors of Pediatric Cushing DiseaseParticipants currently recruited/enrolled2-90 YearsNICHDBone
19-CH-0026Randomized, Double-Blind, Placebo-Controlled Study Plus Open Label Extension with a Double-Blind, Placebo-Controlled, Randomized Withdrawal Period of Diazoxide Choline Extended-Release Tablets (DCCR, Soleno Therapeutics, Inc.) in Participants with PraderNo longer recruiting/follow-up only4-125 YearsNICHDGenetic
19-CH-0020A Phase 1-2 Multi-Center Study to Assess the Efficacy and Safety of Abiraterone Acetate as Adjunctive Therapy in Pre-Pubescent Children with Classic 21-Hydroxylase DeficiencyRecruitment has not started2-9 YearsNICHDGenetic
19-C-0138Phase I/II Study of Lu-177-DOTATATE (Lutathera) in Combination with Olaparib in Inoperable Gastroenteropancreatico Neuroendocrine Tumors (GEP-NET)Participants currently recruited/enrolled18-125 YearsNCI Rare
19-C-0136A Phase 2, Randomized, Multicenter Study to Evaluate the Efficacy and Safety of KD025 in Subjects with Chronic Graft Versus Host Disease (CGVHD) After at Least 2 Prior Lines of Systemic TherapyCompleted Study; data analyses ongoing18-125 YearsNCI Bone
19-C-0116A Phase 2 Study of Acalabrutinib with DA-EPOCH-R or R-CHOP for Patients with Untreated Diffuse Large B-cell LymphomaParticipants currently recruited/enrolled18-125 YearsNCI Bone
19-C-0112Phase I/II Study De-intensifying Exposure of Post-transplantation Cyclophosphamide as GVHD Prophylaxis after HLA-haploidentical Hematopoietic Cell Transplantation for Hematologic MalignanciesParticipants currently recruited/enrolled12-125 YearsNCI Bone
19-C-0102A Phase I Clinical Trial of T-cells Expressing an anti-SLAMF7 CAR for Treating Multiple MyelomaCompleted Study; data analyses ongoing18-73 YearsNCI Bone
19-C-0085Phase II Trial of Allogeneic Hematopoietic Cell Transplantation for Peripheral T cell LymphomaClinical hold/Recruitment or enrollment suspended12-125 YearsNCI Bone
19-C-0076A Phase 1 Study of Interleukin-15 in Combination with Avelumab (Bavencio) in Relapsed/Refractory Mature T-cell MalignanciesCompleted Study; data analyses ongoing18-125 YearsNCI Bone
19-C-0061A Phase 2 Trial of the MEK Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in Combination with the mTOR Inhibitor Sirolimus for Patients with Unresectable or Metastatic Malignant Peripheral Nerve Sheath TumorsParticipants currently recruited/enrolled12-125 YearsNCI Genetic
19-C-0040Natural History Study of Men at High Genetic Risk for Prostate CancerParticipants currently recruited/enrolled30-75 YearsNCI Genetic
19-C-0030A Phase 2 Study of Response-Adapted Therapy with Copanlisib and Rituximab in Untreated Follicular LymphomaParticipants currently recruited/enrolled18-125 YearsNCI Bone
19-C-0023A Phase II Study of Olaparib (AZD2281) in Patients with Metastatic/Advanced Urothelial Carcinoma and other genitourinary tumors with DNA-Repair DefectsParticipants currently recruited/enrolled18-125 YearsNCI Genetic
19-C-0017A Phase I/II Study Administering Peripheral Blood Lymphocytes Transduced with a Murine T-Cell Receptor Recognizing the G12D Variant of Mutated RAS in HLA-A*11:01 PatientsParticipants currently recruited/enrolled18-70 YearsNCI Genetic
18-N-0140Clinical Laboratory Evaluation of Chronic Autonomic FailureParticipants currently recruited/enrolled18-125 YearsNINDSBone
18-N-0077Cytokine Microdialysis For Real Time Immune Monitoring in Glioblastoma Patients Undergoing Checkpoint BlockadeCompleted Study; data analyses ongoing18-125 YearsNINDSBone
18-I-0128Send-In Sample Collection to Achieve Genetic and Immunologic Characterization of Primary ImmunodeficienciesParticipants currently recruited/enrolled0-99 YearsNIAIDGenetic
18-I-0092A Phase 2, Open-Label Study to Assess the Immunogenicity of the 9-Valent Human Papillomavirus Recombinant Vaccine in Patients with Idiopathic CD4 T cell LymphocytopeniaParticipants currently recruited/enrolled18-70 YearsNIAIDRare
18-I-0041Investigating the Mechanistic Biology of Primary Immunodeficiency DisordersParticipants currently recruited/enrolled0-75 YearsNIAIDGenetic
18-HG-0129Reverse Phenotyping Core (RPC)Enrolling by Invitation4-125 YearsNHGRIGenetic
18-HG-0064A Natural History Study of Patients with Generalized Arterial Calcification of Infancy (GACI) or Autosomal Recessive Hypophosphatemic Rickets Type 2 (ARHR2)Completed Study; data analyses ongoing0-125 YearsNHGRIRare
18-H-0146Genotype -Phenotype Correlation of PKLR Variants with Pyruvate Kinase, 2,3-Diphosphglycerate and ATP Activities in Red Blood Cells of Patients with Sickle Cell DiseaseParticipants currently recruited/enrolled18-80 YearsNHLBIGenetic
18-H-0090Haplo-identical Transplantation for Severe Aplastic Anemia, Hypo-plastic MDS and PNH using Peripheral Blood Stem Cells and post-transplant Cyclophosphamide for GVHD prophylaxisParticipants currently recruited/enrolled4-75 YearsNHLBIBone
18-H-0012A Phase I Study of HERV-E TCR Transduced Autologous T Cells in Patients with Metastatic Clear Cell Renal Cell CarcinomaParticipants currently recruited/enrolled18-75 YearsNHLBIGenetic
18-H-0004Low Dose Danazol for the Treatment of Telomere Related DiseasesParticipants currently recruited/enrolled3-125 YearsNHLBIBone
18-H-0003Discovery of Sirolimus Sensitive Biomarkers in BloodParticipants currently recruited/enrolled18-90 YearsNHLBIRare
18-DK-0091Long-Term Follow-Up Of Subjects With CHC Who Achieved A Sustained Virological Response Following Therapy With Direct Acting Antiviral AgentsParticipants currently recruited/enrolled18-125 YearsNIDDKGenetic
18-DC-0051Biospecimen Procurement for NIDCD Clinical ProtocolsParticipants currently recruited/enrolled0-99 YearsNIDCDGenetic
18-D-0114An Open Label Pilot Study of Denosumab Treatment for Fibrous DysplasiaNo longer recruiting/follow-up only18-125 YearsNIDCRBone
18-CH-0120A Natural History of the Collagen-Related Disorder Osteogenesis Imperfecta and the Genotype-Phenotype CorrelationNo longer recruiting/follow-up only0-125 YearsNICHDBone
18-CH-0002Investigations of Juvenile Neuronal Ceroid Lipofuscinosis (CLN3)Participants currently recruited/enrolled0-125 YearsNICHDGenetic
18-C-0143A Phase 1 Study of Intraperitoneal MCY-M11 Therapy for Women with Platinum Resistant High Grade Serous Adenocarcinoma of the Ovary, Primary Peritoneum, or Fallopian Tube, or Subjects with Peritoneal Mesothelioma with Recurrence after Prior ChemotherapyCompleted Study; data analyses ongoing18-125 YearsNCI Genetic
18-C-0135Phase II Trial of Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or DysregulationParticipants currently recruited/enrolled4-125 YearsNCI Bone
18-C-0125A Phase I Clinical Trial of T cells Expressing a Novel Fully-human Anti-BCMA CAR for Treating Multiple MyelomaNo longer recruiting/follow-up only18-73 YearsNCI Bone
18-C-0102Pilot Study of the MEK1/2 Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) for Adults with Neurofibromatosis Type 1 (NF1) and Cutaneous Neurofibromas (cNF)Completed Study; data analyses ongoing18-125 YearsNCI Genetic
18-C-0093Pilot Study of Medication Adherence in Children, Adolescents, and Adults with Neurofibromatosis Type 1 (NF1) on Clinical Treatment TrialsNo longer recruiting/follow-up only3-125 YearsNCI Genetic
18-C-0078A Phase I/II Study of Immunotherapy Combination BN-Brachyury vaccine, M7824, N-803 and Epacadostat (QuEST1)Participants currently recruited/enrolled18-125 YearsNCI Bone
18-C-0076Bicalutamide With or Without Metformin for Biochemical Recurrence in Prostate Cancer Patients (BIMET-1)Completed Study; data analyses ongoing18-85 YearsNCI Bone
18-C-0062Phase 2 Trial of XL184 (Cabozantinib) an Oral Small-Molecule Inhibitor of Multiple Kinases, in Children and Young Adults with Refractory Sarcomas, Wilms Tumor, and Other Rare TumorsCompleted Study; data analyses ongoing2-30 YearsNCI Rare
18-C-0059Phase 1 Dose Escalation Study of CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults with Recurrent or Refractory CD19/CD22-expressing B Cell MalignanciesParticipants currently recruited/enrolled3-39 YearsNCI Bone
18-C-0049A Phase II Study Using the Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Neoantigens in Patients with Metastatic CancerParticipants currently recruited/enrolled18-72 YearsNCI Genetic
18-C-0038Long Term Follow-up (LTFU) of Participants Treated with GSK Adoptive Cell TherapiesNo longer recruiting/follow-up only4-125 YearsNCI Genetic
18-C-0034A Phase 2 Study of ONC201 in Recurrent/Refractory Metastatic Breast Cancer and Advanced Endometrial CarcinomaCompleted Study; data analyses ongoing18-125 YearsNCI Bone
18-C-0026A Phase 2 Study of Inotuzumab Ozogamicin (NSC# 772518, IND#133494) in Children and Young Adults with Relapsed or Refractory CD22+ B-Acute Lymphoblastic Leukemia (B-ALL)Participants currently recruited/enrolled1-21 YearsNCI Bone
18-C-0005Phase II Trial of Combination Immunotherapy in Biochemically Recurrent Prostate CancerParticipants currently recruited/enrolled18-125 YearsNCI Bone
17-N-0145PD-1 Inhibition to Determine CNS Reservoir of HIV-InfectionCompleted Study; data analyses ongoing18-120 YearsNINDSBone
17-M-0181Recruitment and Characterization of Healthy Research Volunteers for NIMH Intramural StudiesParticipants currently recruited/enrolled18-125 YearsNIMH Genetic
17-I-0122NIAID Centralized Sequencing ProtocolParticipants currently recruited/enrolled0-125 YearsNIAIDGenetic
17-I-0083Targeting Residual Activity By Precision, Biomarker-Guided Combination Therapies of Multiple Sclerosis (TRAP-MS)Participants currently recruited/enrolled18-125 YearsNIAIDBone
17-H-0124Peripheral Blood Stem Cell Collection for Sickle Cell Disease (SCD) Patients Using PlerixaforCompleted Study; data analyses ongoing18-125 YearsNHLBIBone
17-H-0091Unrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS using CordIn, Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells, to Expedite Engraftment and Improve Transplant OutcomeParticipants currently recruited/enrolled4-75 YearsNHLBIBone
17-H-0056Pathophysiology of Acute Pain in Patients with Sickle Cell DiseaseCompleted Study; data analyses ongoing18-80 YearsNHLBIGenetic
17-H-0026Pembrolizumab and Decitabine for Refractory or Relapsed Acute Myeloid LeukemiaCompleted Study; data analyses ongoing18-99 YearsNHLBIBone
17-H-0019A Randomized Trial of Sirolimus (Rapamune(R)) for Relapse Prevention in Patients with Severe Aplastic Anemia Responsive to Immunosuppressive TherapyParticipants currently recruited/enrolled2-125 YearsNHLBIBone
17-CH-0020Observational Study of Males with Creatine Transporter Deficiency (CTD)No longer recruiting/follow-up only2-40 YearsNICHDRare
17-C-0174Molecular Characterization of Viral-associated Tumors, Tumors Occurring in the Setting of HIV or Other Immune Disorders and Castleman DiseaseParticipants currently recruited/enrolled18-125 YearsNCI Genetic
17-C-0164A Phase 1b/2 Trial of Hu5F9-G4 in Combination with Rituximab or Rituximab + Chemotherapy in Patients with Relapsed/Refractory B-cell Non-Hodgkin's LymphomaNo longer recruiting/follow-up only18-125 YearsNCI Bone
17-C-0127Phase 1b/2 Study of Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (ViPOR) in Relapsed/Refractory B-cell LymphomaParticipants currently recruited/enrolled18-125 YearsNCI Bone
17-C-0125Phase 2 Trial of Nivolumab in Epstein-Barr Virus (EBV)-Positive Lymphoproliferative Disorders and EBV-Positive Non-Hodgkin LymphomasParticipants currently recruited/enrolled12-125 YearsNCI Bone
17-C-0113A Phase I/II Study Administering Peripheral Blood Lymphocytes Transduced with a Murine T-Cell Receptor Recognizing the G12V Variant of Mutated RAS in HLA-A*11:01 PatientsParticipants currently recruited/enrolled18-70 YearsNCI Genetic
17-C-0105Prospective Study of Clonal Evolution in Follicular LymphomaParticipants currently recruited/enrolled18-125 YearsNCI Bone
17-C-0092A Phase I/II Study of Pexa-Vec Oncolytic Virus in Combination with Immune Checkpoint Inhibition in Refractory Colorectal CancerCompleted Study; data analyses ongoing18-125 YearsNCI Genetic
17-C-0090DART: Dual Anti-CTLA-4 And Anti-Pd-1 Blockade In Rare TumorsParticipants currently recruited/enrolled18-125 YearsNCI Rare
17-C-0087Lu-177-DOTATATE (Lutathera) in Therapy of Inoperable Pheochromocytoma/ ParagangliomaParticipants currently recruited/enrolled18-125 YearsNCI Rare
17-C-0066A Pilot Study to Investigate the Safety and Clinical Activity of Avelumab (MSB0010718C) in Thymoma and Thymic Carcinoma after Progression on Platinum-Based ChemotherapyParticipants currently recruited/enrolled18-125 YearsNCI Genetic
17-C-0061Phase II Trial of Pembrolizumab in Recurrent or Metastatic Medullary Thyroid CancerCompleted Study; data analyses ongoing18-125 YearsNCI Bone
17-C-0044Prospective Evaluation and Molecular Profiling in Patients with Gastric TumorsParticipants currently recruited/enrolled2-125 YearsNCI Rare
17-C-0043Hereditary Gastric Cancer Syndromes: An Integrated Genomic and Clinicopathologic Study of the Predisposition to Gastric CancerParticipants currently recruited/enrolled2-125 YearsNCI Genetic
17-C-0028A Pilot Study of Vincristine Sulfate Liposome Injection (Marqibo ) in Combination with Chemotherapy for Children, Adolescents, and Young Adults with Relapse of Acute Lymphoblastic LeukemiaCompleted Study; data analyses ongoing2-21 YearsNCI Bone
17-C-0027Long-Term Follow up of Patients Undergoing Hematopoietic Stem Cell TransplantationParticipants currently recruited/enrolled4-125 YearsNCI Bone
17-C-0007Phase I/II Study of PROSTVAC in Combination with Nivolumab in Men with Prostate CancerParticipants currently recruited/enrolled18-125 YearsNCI Bone
17-AA-0171Nicotinic Receptor Genetic Variation and Alcohol RewardParticipants currently recruited/enrolled21-60 YearsNIAAAGenetic
16-N-0058Myalgic Encephalomyelitis/Chronic Fatigue SyndromeCompleted Study; data analyses ongoing18-60 YearsNINDSBone
16-I-0165An open-label, non-randomized extension study to evaluate the long term safety, tolerability, efficacy and pharmacokinetics of CDZ173 (leniolisib) in patients with APDS/PASLI (Activated phosphoinositide 3-kinase delta syndrome/p110 delta-activating mutatNo longer recruiting/follow-up only12-75 YearsNIAIDRare
16-I-0065Screening for Alpha Globin DeletionsParticipants currently recruited/enrolled18-39 YearsNIAIDGenetic
16-I-0032High Dose Peripheral Blood Stem Cell Transplantation with Post Transplant Cyclophosphamide for Patients with Chronic Granulomatous DiseaseNo longer recruiting/follow-up only4-65 YearsNIAIDBone
16-HG-0156The Natural History, Physiology, Microbiome and Biochemistry Studies of Propionic AcidemiaParticipants currently recruited/enrolled0-125 YearsNHGRIGenetic
16-H-0074Williams Syndrome (WS) and Supravalvular Aortic Stenosis (SVAS) DNA and Tissue BankParticipants currently recruited/enrolled0-85 YearsNHLBIRare
16-H-0063Williams Syndrome Skin and Vascular Elasticity Study (WS-SAVE Study)Completed Study; data analyses ongoing1-70 YearsNHLBIGenetic
16-EI-0104Clinical and Molecular Studies in Families with Inherited Eye DiseaseParticipants currently recruited/enrolled4-125 YearsNEI Genetic
16-EI-0090Natural History of Spinocerebellar Ataxia Type 7 (SCA7)Participants currently recruited/enrolled12-125 YearsNEI Genetic
16-EI-0046Uveitis/Intraocular Inflammatory Disease Biobank (iBank)No longer recruiting/follow-up only8-125 YearsNEI Genetic
16-E-0096Cytochrome P450 Epoxygenase Pathway Regulation of Macrophage FunctionParticipants currently recruited/enrolled18-65 YearsNIEHSGenetic
16-E-0006Investigating the Impact of Obesity on Pubertal Development in GirlsParticipants currently recruited/enrolled8-14 YearsNIEHSBone
16-DK-0173MEASuRE: Metreleptin Effectiveness and Safety RegistryParticipants currently recruited/enrolled0-125 YearsNIDDKRare
16-DK-0143Idiosyncratic Liver Injury Associated with Drugs (ILIAD): A Retrospective StudyParticipants currently recruited/enrolled18-125 YearsNIDDKGenetic
16-DK-0068The Molecular, Cellular, and Genetic Characterization of Human Adipose Tissue and its Role in MetabolismParticipants currently recruited/enrolled18-125 YearsNIDDKGenetic
16-CH-0103Evaluation of Patients with Genetic DisordersParticipants currently recruited/enrolled0-125 YearsNICHDGenetic
16-CC-0149Dopamine and Motor Learning in Cerebral PalsyParticipants currently recruited/enrolled5-25 YearsCC Genetic
16-CC-0001Evaluation of MiSeq for Microbial Identification in SpecimensEnrolling by Invitation2-125 YearsCC Genetic
16-C-0154A Phase I/II Trial of T Cell Receptor Gene Therapy Targeting HPV-16 E7 for HPV-Associated CancersParticipants currently recruited/enrolled18-125 YearsNCI Genetic
16-C-0076Prospective Screening for Patient Specific Genotypes and Phenotypes that Influence Drug Dosing and Trial Selection in Cancer PatientsEnrolling by Invitation18-125 YearsNCI Genetic
16-C-0066Phase I Study of MK-3475 (Pembrolizumab) in Patients with Human Immunodeficiency Virus (HIV) and Relapsed/Refractory or Disseminated Malignant NeoplasmParticipants currently recruited/enrolled18-125 YearsNCI Bone
16-C-0062A Phase I Study of Subcutaneous Recombinant Human IL-15 (S.C. Rhil-15) and Alemtuzumab for Patients with Refractory or Relapsed Chronic and Acute Adult T-Cell Leukemia (ATL)Completed Study; data analyses ongoing18-125 YearsNCI Rare
16-C-0061Biospecimen Procurement for Center for Immuno-Oncology Immunotherapy ProtocolsParticipants currently recruited/enrolled18-125 YearsNCI Bone
16-C-0054T Cells Expressing a Fully-human Anti- CD19 Chimeric Antigen Receptor for Treating B-cell MalignanciesNo longer recruiting/follow-up only18-73 YearsNCI Bone
16-C-0048Docetaxel and Prostvac for Metastatic Castration Sensitive Prostate CancerNo longer recruiting/follow-up only18-125 YearsNCI Bone
16-C-0035Prostvac in Patients with Biochemically Recurrent Prostate CancerNo longer recruiting/follow-up only18-125 YearsNCI Bone
16-C-0003Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary ImmunodeficienciesParticipants currently recruited/enrolled4-75 YearsNCI Bone
16-AA-0037Effect of Opioid Receptor Modulation on Alcohol Self-Administration and Neural Response to Alcohol Cues in Heavy Drinkers: Role of OPRM1 Gene VariationParticipants currently recruited/enrolled21-60 YearsNIAAAGenetic
15-N-0175An Open-Label, Phase 1b Safety and Efficacy Trial of Periganglionic Resiniferatoxin for the Treatment of Intractable Pain due to Cancer-induced Bone PainRecruitment has not started18-150 YearsNINDSBone
15-N-0125Natural History Study of Inflammatory and Infectious Diseases of the Nervous SystemParticipants currently recruited/enrolled2-125 YearsNINDSBone
15-M-0151An Investigation of the Antidepressant Effects of the Glycine Receptor Antagonist AV 101 (4-chlorokynurenine) in Major Depressive DisorderCompleted Study; data analyses ongoing18-65 YearsNIMH Bone
15-I-0162Natural History and Genetics of Food Allergy and Related ConditionsParticipants currently recruited/enrolled0-99 YearsNIAIDGenetic
15-I-0135An open-label, non-randomized, within-patient dose-finding study followed by a randomized, subject, investigator and sponsor-blinded placebo controlled study to assess the efficacy and safety of CDZ173 (leniolisib) in patients with APDS/PASLI (Activated Completed Study; data analyses ongoing12-75 YearsNIAIDRare
15-I-0008A Phase I/II, Non Randomized, Multicenter, Open-Label Study of G1XCGD (Lentiviral Vector Transduced CD34+ Cells) in Patients with X-linked Chronic Granulomatous Disease (CGD)Completed Study; data analyses ongoing3-65 YearsNIAIDBone
15-H-0155Hereditary Parkinson Disease Natural History ProtocolCompleted Study; data analyses ongoing18-80 YearsNHLBIGenetic
15-H-0024Genes Involved in Lipid DisordersCompleted Study; data analyses ongoing2-99 YearsNHLBIGenetic
15-H-0017Characterization of Apolipoprotein A-I Pathways in Idiopathic Pulmonary FibrosisCompleted Study; data analyses ongoing18-100 YearsNHLBIGenetic
15-H-0016A Phase II Study Using ACP-196 in Patients with Relapsed/Refractory and Treatment Naive Deletion 17p CLL/SLL: Pharmacodynamic Assessment of BTK Inhibition and Anti-Tumor Response.No longer recruiting/follow-up only18-125 YearsNHLBIBone
15-EI-0038A Phase I/IIa Study of RS1 Ocular Gene Transfer for X-linked RetinoschisisNo longer recruiting/follow-up only18-125 YearsNEI Genetic
15-DK-0119Thyroid Hormone to Induce Non-Insulin Mediated Glucose Disposal in Patients with Insulin Receptor MutationsCompleted Study; data analyses ongoing12-65 YearsNIDDKBone
15-DK-0003Compassionate Use of Metreleptin in Previously-Treated Patients with Generalized LipodystrophyParticipants currently recruited/enrolled0-125 YearsNIDDKBone
15-DK-0002Compassionate Use of Metreleptin in Previously-Treated Patients with Partial LipodystrophyNo longer recruiting/follow-up only0-125 YearsNIDDKBone
15-D-0051Characterization of Diseases with Salivary Gland InvolvementParticipants currently recruited/enrolled4-125 YearsNIDCRGenetic
15-CH-0096Children's Growth and Behavior StudyParticipants currently recruited/enrolled8-125 YearsNICHDGenetic
15-C-0200Molecular Analysis for Therapy Choice (MATCH) (EAY131)Completed Study; data analyses ongoing18-125 YearsNCI Genetic
15-C-0160A Phase I Study of Cabozantinib Plus Nivolumab (CaboNivo) Alone or in Combination with Ipilimumab (CaboNivoIpi) in Patients with Advanced/Metastatic Urothelial Carcinoma and other Genitourinary TumorsNo longer recruiting/follow-up only18-125 YearsNCI Bone
15-C-0157Phase I/II Trial of Vandetanib in Combination with Metformin in Subjects with HLRCC or SDH-Associated Kidney Cancer or Sporadic Papillary Renal Cell CarcinomaCompleted Study; data analyses ongoing18-125 YearsNCI Bone
15-C-0141Gene Therapy Follow up Protocol for Subjects Previously Enrolled in CAR T-Cell StudiesEnrolling by Invitation18-125 YearsNCI Genetic
15-C-0124Neoadjuvant Androgen Deprivation and Enzalutamide: Using Multiparametric MRI to Evaluate Intraprostatic Tumor Responses and Androgen Resistance Patterns in Newly Diagnosed Prostate CancerNo longer recruiting/follow-up only18-125 YearsNCI Genetic
15-C-0093Phase I Trial of Turalio(R) (pexidartinib, PLX3397) in Children and Young Adults with Refractory Leukemias and Refractory Solid Tumors Including Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PN)Participants currently recruited/enrolled3-35 YearsNCI Bone
15-C-0067A Phase I/II Open Label, Dose Escalation Study of Palifermin (Kepivance) in Persons Undergoing Unrelated Donor Allogeneic Hematopoietic Cell TransplantationParticipants currently recruited/enrolled18-125 YearsNCI Bone
15-C-0029Phase I Dose Escalation Study of Anti-CD22 Chimeric Receptor T Cells in Pediatric and Young Adults with Recurrent or Refractory CD22-expressing B Cell MalignanciesParticipants currently recruited/enrolled3-39 YearsNCI Bone
15-C-0028Follow-Up Evaluation for Gene-Therapy Related Delayed Adverse Events After Participation in Pediatric Oncology Branch Clinical TrialsEnrolling by Invitation1-99 YearsNCI Genetic
15-C-0019The Impact of Ras/MAPK Signaling Pathway-Targeted Therapies on Neurocognitive Functioning in Individuals with NF1Completed Study; data analyses ongoing4-99 YearsNCI Genetic
15-AR-0144Studies of Dermatologic Diseases-Biospecimen Acquisition ProtocolParticipants currently recruited/enrolled2-125 YearsNIAMSRare
15-AR-0060The Role of PPAR-gamma Agonists in immunomodulation and Vascular Prevention in SLE (PPAR-SLE)Completed Study; data analyses ongoing18-99 YearsNIAMSBone
15-AG-0123Intermittent Calorie Restriction, Insulin Resistance, and Biomarkers of Brain FunctionCompleted Study; data analyses ongoing55-70 YearsNIA Bone
15-AG-0063The Genetic and Epigenetic Signatures of Translational Aging Laboratory Testing (GESTALT)Participants currently recruited/enrolled20-125 YearsNIA Genetic
15-AA-0127(Epi)genetic Modulators of Fear Extinction in Alcohol DependenceParticipants currently recruited/enrolled21-65 YearsNIAAAGenetic
14-I-0185A Phase III Double-Blind Randomized Crossover Study of Plerixafor Versus G-CSF in the Treatment of Patients with WHIM Syndrome.Completed Study; data analyses ongoing10-75 YearsNIAIDRare
14-I-0124PET Imaging and Lymph Node Assessment of IRIS in Persons With AIDSParticipants currently recruited/enrolled18-125 YearsNIAIDGenetic
14-I-0091Analysis of Patients Treated for Chronic Granulomatous Disease Since January 1, 1995Completed Study; data analyses ongoing3-125 YearsNIAIDRare
14-I-0081A Phase 2a Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Subcutaneous Benralizumab (MEDI-563) in Reducing Eosinophilia in Subjects with Hypereosinophilic Syndrome (HES)No longer recruiting/follow-up only18-75 YearsNIAIDBone
14-I-0063An Open-Label, Proof-of-Concept Study to Evaluate the Safety and Efficacy of Dexpramipexole (KNS-760704) in Subjects with Hypereosinophilic SyndromeNo longer recruiting/follow-up only18-125 YearsNIAIDBone
14-HG-0125Insights Into Microbiome and Environmental Contributions to Sickle Cell Disease and Leg UlcersParticipants currently recruited/enrolled18-125 YearsNHGRIGenetic
14-HG-0071Clinical and Basic Investigations into Known and Suspected Congenital Disorders of GlycosylationParticipants currently recruited/enrolled1-80 YearsNHGRIBone
14-HG-0055Study on Moebius Syndrome and Other Congenital Facial Weakness DisordersCompleted Study; data analyses ongoing2-80 YearsNHGRIGenetic
14-H-0155A Phase 1/2 Study Evaluating Gene Therapy by Transplantation of Autologous CD34+ Stem Cells Transduced Ex Vivo with the LentiGlobin BB305 Lentiviral Vector in Subjects with Severe Sickle Cell DiseaseNo longer recruiting/follow-up only18-50 YearsNHLBIBone
14-H-0127Characterization of the Pathogenesis of Primary and Secondary Lymphatic DisordersParticipants currently recruited/enrolled2-90 YearsNHLBIGenetic
14-H-0077Nonmyeloablative Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease and Beta-Thalassemia in Individuals with Higher Risk of Transplant FailureParticipants currently recruited/enrolled4-125 YearsNHLBIBone
14-EI-0064Whole Exome and Whole Genome Sequencing for Genotyping of Inherited and Congenital Eye ConditionsParticipants currently recruited/enrolled1-125 YearsNEI Genetic
14-DK-0195Acute Effects of Canagliflozin, a Sodium Glucose Co-Transporter 2 (SGLT2) Inhibitor on Bone Metabolism in Healthy VolunteersCompleted Study; data analyses ongoing18-125 YearsNIDDKBone
14-C-0163Transformation of Plexiform Neurofibromas to Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis Type 1: Clinical, Histopathologic, and Genomic AnalysisCompleted Study; data analyses ongoing10-125 YearsNCI Genetic
14-C-0157Phase 1 Study of Ibrutinib and Immuno-Chemotherapy Using Temozolomide, Etoposide, Doxil, Dexamethasone, Ibrutinib, Rituximab (TEDDI-R) in Primary CNS LymphomaParticipants currently recruited/enrolled18-125 YearsNCI Rare
14-C-0131A Phase II, Open-Label Study in Patients With BRAF V600E-Mutated Rare Cancers With Several Histologies to Investigate the Clinical Efficacy and Safety of the Combination Therapy of Dabrafenib and TrametinibCompleted Study; data analyses ongoing18-125 YearsNCI Rare
14-C-0105Tissue Procurement and Natural History Study of Patients with Non-Small Cell Lung Cancer, Small Cell Lung Cancer, Extrapulmonary Small Cell Cancer, Pulmonary Neuroendocrine Tumors, and Thymic Epithelial TumorsParticipants currently recruited/enrolled18-125 YearsNCI Genetic
14-C-0059A Phase I Trial of T Cells Expressing an Anti-GD2 Chimeric Antigen Receptor in Children and Young Adults with GD2+ Solid TumorsCompleted Study; data analyses ongoing1-35 YearsNCI Genetic
14-C-0052A Phase I/II Study of the Treatment of Metastatic Cancer that Expresses MAGE-A3 Using Lymphodepleting Conditioning Followed by Infusion of HLA-DP0401/0402 Restricted Anti-MAGE-A3 TCR-Gene Engineered Lymphocytes and AldesleukinCompleted Study; data analyses ongoing18-70 YearsNCI Genetic
14-C-0004A Multicenter Phase 2 Study of the Bruton's Tyrosine Kinase Inhibitor PCI-32765 (Ibrutinib) for Treatment of Relapsed Hairy Cell LeukemiaNo longer recruiting/follow-up only18-125 YearsNCI Bone
14-AR-0200Studies of the Natural History, Pathogenesis, and Outcome of Idiopathic Systemic VasculitisParticipants currently recruited/enrolled3-125 YearsNIAMSGenetic
14-AA-0181NIAAA Natural History ProtocolParticipants currently recruited/enrolled18-100 YearsNIAAAGenetic
13-N-0188Natural History and Biomarkers of C9ORF72 Amyotrophic Lateral Sclerosis and Frontotemporal DementiaCompleted Study; data analyses ongoing18-125 YearsNINDSGenetic
13-N-0085Clinical Manifestations and Biorepository for Focal DystoniaCompleted Study; data analyses ongoing18-125 YearsNINDSGenetic
13-N-0017Natural History Study of Progressive Multifocal Leukoencephalopathy (PML)Participants currently recruited/enrolled2-125 YearsNINDSBone
13-M-0028Diagnosis of Childhood-onset Behavioral Disorders, Neuropsychiatric Disorders and Neurodevelopmental DisordersParticipants currently recruited/enrolled0-99 YearsNIMH Genetic
13-I-0157The Natural History of GATA2 Deficiency and Related DisordersParticipants currently recruited/enrolled2-100 YearsNIAIDGenetic
13-H-0133Extended Dosing with Eltrombopag in Refractory Severe Aplastic AnemiaCompleted Study; data analyses ongoing2-125 YearsNHLBIBone
13-H-0060Analysis of Samples Collected from a Subject who Received ACP- 501 (Human Recombinant Lecithin:Cholesterol Acyltransferase [rhLCAT])Completed Study; data analyses ongoing18-100 YearsNHLBIGenetic
13-H-0059Longitudinal Observational Study of Severe AsthmaParticipants currently recruited/enrolled18-125 YearsNHLBIBone
13-H-0051Bronchodilator Effects of Nebulized versus Inhaled Albuterol in Subjects with LymphangioleiomyomatosisParticipants currently recruited/enrolled18-125 YearsNHLBIRare
13-EI-0049Pathogenesis and Genetics of Microphthalmia, Anophthalmia and Uveal Coloboma ( MAC)Participants currently recruited/enrolled1-125 YearsNEI Genetic
13-E-0015Environmental Risk Factors for the Development of Myositis in Military PersonnelNo longer recruiting/follow-up only18-125 YearsNIEHSRare
13-DK-0091Combination Therapy of Pegylated Interferon Alfa-2a and Tenofovir DF versus Tenofovir DF Monotherapy in HBeAg-Positive and HBeAg-Negative Chronic Hepatitis BCompleted Study; data analyses ongoing18-125 YearsNIDDKBone
13-DA-N485Multimodal Neuroimaging Genetic Biomarkers of Nicotine Addiction SeverityParticipants currently recruited/enrolled18-60 YearsNIDA Genetic
13-CH-0112Pilot Study to Assess Biomarkers of Changes in Barrier Function of Skeletal Muscle in Patients with a Fragile Sarcolemmal Muscular DystrophyNo longer recruiting/follow-up only18-125 YearsNICHDGenetic
13-CH-0001Intrathecal 2-Hydroxypropyl-B-Cyclodextrin in Patients with Niemann-Pick Disease, Type C1Completed Study; data analyses ongoing2-125 YearsNICHDGenetic
13-CC-0012A Natural History Study of Novel Biomarkers in Pulmonary Arterial HypertensionParticipants currently recruited/enrolled18-125 YearsCC Rare
13-C-0202Tissue Procurement and Natural History Study of Patients with Malignant Mesothelioma and Other Mesothelin Expressing CancersParticipants currently recruited/enrolled2-125 YearsNCI Genetic
13-C-0175A Phase II Protocol for Subjects with Stage T1 Bladder Cancer to Evaluate Selective Bladder Preserving Treatment by Radiation Therapy Concurrent with Radio-sensitizing Chemotherapy following a Thorough Transurethral Surgical Re-StagingCompleted Study; data analyses ongoing18-125 YearsNCI Bone
13-C-0153A Phase II Trial of Enzalutamide in Combination with PSA-TRICOM in Patients with Non-Metastatic Castration Sensitive Prostate CancerCompleted Study; data analyses ongoing18-125 YearsNCI Bone
13-C-0132Allogeneic Hematopoietic Stem Cell Transplant for Patients with Mutations in GATA2 or the MonoMAC SyndromeParticipants currently recruited/enrolled8-70 YearsNCI Bone
13-C-0105Molecular Profiling-based Assignment of Cancer Therapy for Patients With Advanced Solid TumorsCompleted Study; data analyses ongoing18-120 YearsNCI Genetic
13-C-0044A Phase 2 Study of Cabozantinib (XL184), a Dual Inhibitor of MET and VEGFR, in Patients With Metastatic Refractory Soft Tissue SarcomaNo longer recruiting/follow-up only18-120 YearsNCI Rare
12-N-0122Integrating Genetic and Environmental Risk Scores into an Algorithm to Predict Multiple Sclerosis SusceptibilityCompleted Study; data analyses ongoing18-125 YearsNINDSGenetic
12-HG-0202The Neurobehavioral, Environmental and Genetic Factors Impacting the Clinical Course of Attention Deficit Hyperactivity DisorderParticipants currently recruited/enrolled3-125 YearsNHGRIGenetic
12-HG-0181The Clinical Study of Patients with Sex Chromosome VariantsCompleted Study; data analyses ongoing18-125 YearsNHGRIGenetic
12-HG-0023The Role of the Family Genetics Health Educator in Influencing Health Promoting BehaviorsCompleted Study; data analyses ongoing18-125 YearsNHGRIGenetic
12-HG-0022Inherited Diseases, Caregiving, and Social NetworksCompleted Study; data analyses ongoing18-125 YearsNHGRIGenetic
12-E-0061The Role of the Functionally Relevant Single Nucleotide Polymorphisms CYP2J2 -50G>T (CYP2J2 7) and EPHX2 9846A>G (EPHX2 K55R) in Human Endothelial FunctionCompleted Study; data analyses ongoing18-65 YearsNIEHSGenetic
12-E-0050The Role of Gonadotropin Pulsations in the Regulation of Puberty and FertilityParticipants currently recruited/enrolled14-125 YearsNIEHSBone
12-E-0049The Molecular Basis of Inherited Reproductive DisordersParticipants currently recruited/enrolled0-125 YearsNIEHSGenetic
12-DA-N472Health Outcomes by Neighborhood - HON Study BaltimoreCompleted Study; data analyses ongoing18-100 YearsNIDA Genetic
12-D-0100Oral Microbial and Immunological Characterization of Patients with Immune DysfunctionParticipants currently recruited/enrolled7-125 YearsNIDCRGenetic
12-CC-0211A Pilot Study of the Effect of Spironolactone Therapy on Exercise Capacity and Endothelial Dysfunction in Pulmonary Arterial HypertensionParticipants currently recruited/enrolled18-125 YearsCC Rare
12-CC-0096Collection of Granulocytes by Apheresis of Healthy Donors Stimulated with Filgrastim (G-CSF) and DexamethasoneParticipants currently recruited/enrolled18-125 YearsCC Bone
12-C-0160Validation of the English Version of the Pain Interference Index and the Pain Rating Scale in Children, Adolescents, and Adults with Chronic Illness and their ParentsParticipants currently recruited/enrolled18-125 YearsNCI Genetic
12-C-0112Phase I Study of T Cells Expressing an Anti-CD19 Chimeric Receptor in Children and Young Adults with B Cell MalignanciesCompleted Study; data analyses ongoing1-30 YearsNCI Bone
12-C-0107Carfilzomib, Lenalidomide, and Dexamethasone in High-Risk Smoldering Multiple Myeloma: a Clinical and Correlative Pilot StudyNo longer recruiting/follow-up only18-125 YearsNCI Bone
12-C-0074Mobilization and Collection of Autologous Hematopoietic Progenitor Cell (HPC) for Transplantation (AHCT) for Plasma Cell Myeloma (PCM)Completed Study; data analyses ongoing18-75 YearsNCI Bone
12-C-0068A Randomized Double-Blind Pilot Study of Topical Clobetasol 0.05% Oral rinse for Oral Chronic Graft-Versus-Host DiseaseCompleted Study; data analyses ongoing12-125 YearsNCI Bone
12-C-0047A Phase I/II Study of the Safety, Pharmacokinetics and Efficacy of Pomalidomide (CC-4047) in the Treatment of Kaposi Sarcoma in Individuals With or Without HIVCompleted Study; data analyses ongoing18-125 YearsNCI Rare
12-AR-0159Effects of Treatments on the Microbiome in Healthy Volunteers and Patients with Atopic DermatitisParticipants currently recruited/enrolled2-50 YearsNIAMSGenetic
11-M-0251A Longitudinal Investigation of the Endocrine and Neurobiologic Events Accompanying PubertyParticipants currently recruited/enrolled7-35 YearsNIMH Genetic
11-HG-0218A Natural History Study of Patients with GNE Myopathy and GNE-Related DiseasesParticipants currently recruited/enrolled4-80 YearsNHGRIGenetic
11-HG-0110Genetics of Obesity, Diabetes, and Heart Disease in African Diaspora PopulationsEnrolling by Invitation18-125 YearsNHGRIGenetic
11-H-0134A Pilot Study of a Thrombopoietin-Receptor Agonist (TPO-R Agonist), Eltrombopag, in Moderate Aplastic Anemia PatientsNo longer recruiting/follow-up only2-125 YearsNHLBIBone
11-E-0072Environmental Risk Factors for the Anti-Synthetase SyndromeParticipants currently recruited/enrolled2-100 YearsNIEHSGenetic
11-CC-0120Stereophotogrammetry of the Torso in Healthy Individuals and Patients with Scoliosis, Chest Wall Deformations, or ObesityCompleted Study; data analyses ongoing2-125 YearsCC Bone
11-C-0242Collection of Blood from Patients with Cancer, Other Tumors, or Tumor Predisposition Syndromes for Analysis of Genetic Differences in Drug DispositionParticipants currently recruited/enrolled3-125 YearsNCI Genetic
11-C-0200A Phase II Trial In Which Patients With Metastatic Alveolar Soft Part Sarcoma Are Randomized to Either Sunitinib or Cediranib Monotherapy, with Cross-Over at Disease ProgressionNo longer recruiting/follow-up only16-125 YearsNCI Rare
11-C-0096Pilot Trial of Molecular Profiling and Targeted Therapy for Advanced Non-Small Cell Lung Cancer, Small Cell Lung Cancer, and Thymic MalignanciesNo longer recruiting/follow-up only18-125 YearsNCI Genetic
11-C-0033Extended Follow-up of High Ovarian Cancer Risk Cohort from 02C0268 (GOG-199)Completed Study; data analyses ongoing18-100 YearsNCI Genetic
11-AR-0223Studies on the Natural History and Pathogenesis of SpondyloarthritisParticipants currently recruited/enrolled2-125 YearsNIAMSBone
10-M-0112Defining the Brain Phenotype of Children with Williams SyndromeParticipants currently recruited/enrolled5-125 YearsNIMH Genetic
10-M-0027Cognitive Neuroscience of Autism Spectrum DisordersParticipants currently recruited/enrolled5-89 YearsNIMH Genetic
10-I-0216Studies of Disorders with Increased Susceptibility to Fungal InfectionsParticipants currently recruited/enrolled0-125 YearsNIAIDGenetic
10-I-0148Natural History of Severe Allergic Inflammation and ReactionsParticipants currently recruited/enrolled2-80 YearsNIAIDGenetic
10-I-0014The Natural History of Severe Viral Infections and Characterization of Immune DefectsParticipants currently recruited/enrolled2-125 YearsNIAIDGenetic
10-H-0168Submission of Autologous and Related Allogeneic Hematopoietic Stem Cell Transplant Data to the Center for International Blood and Marrow Transplant Research (CIBMTR) and the National Marrow Donor Program (NMDP)Participants currently recruited/enrolled2-99 YearsNHLBIBone
10-H-0154Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused with a Reduced Dose of Non-Mobilized Donor T-CellsParticipants currently recruited/enrolled4-80 YearsNHLBIBone
10-H-0141A Phase II Study of Ofatumumab-Based Induction Chemoimmunotherapy Followed by Consolidation Ofatumumab Immunotherapy in Previously Untreated Patients with Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma.No longer recruiting/follow-up only18-99 YearsNHLBIBone
10-H-0126Cardiovascular Disease Discovery ProtocolParticipants currently recruited/enrolled1-100 YearsNHLBIGenetic
10-EI-0140Genotype - phenotype Study of Patients with Plaquenil-induced Retinal ToxicityParticipants currently recruited/enrolled18-125 YearsNEI Genetic
10-DK-N091Molecular and Clinical Profile of Diabetes Mellitus and its ComplicationsParticipants currently recruited/enrolled18-125 YearsNIDDKGenetic
10-DK-0102Clinical and Genetic Studies in Familial Non-Medullary Thyroid CancerParticipants currently recruited/enrolled7-125 YearsNIDDKGenetic
10-DA-N457Characterization of Phenotypic and Genotypic RegressorsParticipants currently recruited/enrolled18-125 YearsNIDA Genetic
10-CC-0053Collection of Bone Marrow from Healthy Volunteers and Patients for the Production of Clinical Bone Marrow Stromal Cell (BMSC) ProductsCompleted Study; data analyses ongoing18-125 YearsCC Bone
10-C-0201Apheresis and CD34+ Selection of Mobilized Peripheral Blood CD34+ Cells from Patients with DOCK8 Deficiency, LAD-1, and GATA2 DeficiencyParticipants currently recruited/enrolled18-40 YearsNCI Bone
10-C-0066A Study of Hairy Cell and other Leukemias with a Focus on Recombinant Immunotoxins for Cancer TreatmentParticipants currently recruited/enrolled18-125 YearsNCI Bone
10-C-0056A Phase I Study of Indenoisoquinolines LMP400 and LMP776 in Adults With Relapsed Solid Tumors and LymphomasCompleted Study; data analyses ongoing18-125 YearsNCI Bone
10-C-0025Randomized Phase II Trial of Rituximab with Either Pentostatin or Bendamustine for Multiply Relapsed or Refractory Hairy Cell LeukemiaParticipants currently recruited/enrolled18-125 YearsNCI Bone
09-N-0010Biomarkers of Risk of Parkinson DiseaseCompleted Study; data analyses ongoing18-70 YearsNINDSGenetic
09-I-0126Pathogenesis and Genetic Basis of Physical Induced Urticarial SyndromesParticipants currently recruited/enrolled2-90 YearsNIAIDGenetic
09-I-0102Etiology, Pathogenesis, and Natural History of Idiopathic CD4+ LymphocytopeniaParticipants currently recruited/enrolled18-125 YearsNIAIDGenetic
09-I-0013Biomarkers of Inflammation, Coagulation, and Endothelial Function in HIV-Infected AdultsEnrolling by Invitation18-100 YearsNIAIDGenetic
09-H-0225Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Severe Congenital Anemias Including Sickle Cell Disease and Beta-ThalassemiaNo longer recruiting/follow-up only2-125 YearsNHLBIBone
09-H-0199A Pilot Study of a Thrombopoietin-Receptor Agonist (TPO-R agonist), Eltrombopag, in Patients with Low to Int-2 Risk Myelodysplastic Syndrome (MDS)Completed Study; data analyses ongoing18-125 YearsNHLBIBone
09-H-0172Natural History of BronchiectasisParticipants currently recruited/enrolled5-125 YearsNHLBIGenetic
09-CC-0217Vasti Control of Patellofemoral Kinematics in Asymptomatic VolunteersCompleted Study; data analyses ongoing18-55 YearsCC Bone
09-C-0005Randomized Trial of Cladribine (CdA) with Simultaneous or Delayed Rituximab to Eliminate Hairy Cell Leukemia Minimal Residual DiseaseParticipants currently recruited/enrolled18-125 YearsNCI Bone
08-N-0044A Prospective Natural History Study of Patients with Neurofibromatosis Type 2 (NF2).Participants currently recruited/enrolled8-75 YearsNINDSGenetic
08-H-0186Safety and the Anti- Tumor Effects of Escalating Doses of Adoptively Infused Ex Vivo Expanded Autologous Natural Killer (NK) Cells Against Metastatic Cancers or Hematological Malignancies Sensitized to NK-TRAIL Cytotoxicity with BortezomibCompleted Study; data analyses ongoing18-70 YearsNHLBIBone
08-H-0105Natural History Study of Monoclonal B Cell Lymphocytosis (MBL), Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL), Lymphoplasmacytic Lymphoma (LPL)/Waldenstrom Macroglobulinemia (WM), and Splenic Marginal Zone Lymphoma (SMZL)Participants currently recruited/enrolled18-125 YearsNHLBIBone
08-EI-0102Screening Protocol for the Evaluation and Diagnosis of Potential Research ParticipantsParticipants currently recruited/enrolled2-125 YearsNEI Genetic
07-N-0190Neurobiological Studies of Functional Movement Disorders and Non-Epileptic SeizuresNo longer recruiting/follow-up only18-125 YearsNINDSGenetic
07-I-0183The Collection of Research Samples and/or Data for Repository from Related or Unrelated Hematopoietic Stem Cell Transplantation Recipients for the National Marrow Donor Program Participants currently recruited/enrolled2-125 YearsNIAIDBone
07-I-0033Screening Protocol for Detection and Characterization of Infections and Infection SusceptibilityParticipants currently recruited/enrolled0-125 YearsNIAIDGenetic
07-HG-0002ClinSeq: A Large-Scale Medical Sequencing Clinical Research Pilot StudyNo longer recruiting/follow-up only6-95 YearsNHGRIGenetic
07-H-0005Pilot Study of Topical Dexamethasone 0.01% Solution for Prevention of Oral Chronic Graft Versus Host DiseaseCompleted Study; data analyses ongoing12-110 YearsNHLBIBone
07-DK-N215Study of Short-Term Metabolic Adaptation: Prediction of Weight Change and Effects of Macronutrient ManipulationsCompleted Study; data analyses ongoing18-55 YearsNIDDKGenetic
07-DK-0115Natural History of Type 2 Diabetes Mellitus in Children and Young AdultsCompleted Study; data analyses ongoing8-25 YearsNIDDKGenetic
07-CH-0008Prospective, Open-Label, Multicenter, International Study of Mifepristone for Symptomatic Treatment of Cushing's Syndrome Caused by Ectopic Adrenal Corticotrophin Hormone (ACTH) SecretionCompleted Study; data analyses ongoing18-85 YearsNICHDBone
07-C-0195Phase II Trial of Targeted Immune-Depleting Chemotherapy and Reduced-Intensity Allogeneic Hematopoietic Stem Cell Transplantation Using 8/8 and 7/8 HLA-matched Unrelated Donors and Utilizing Two Graft-versus-Host Disease Prophylaxis Regimens for the TreaCompleted Study; data analyses ongoing18-74 YearsNCI Bone
07-C-0121Phase 2 Study of the C-Met RTK Inhibitor Foretinib (Formerly GSK 1363089) in Subjects with Papillary Renal Cell Carcinoma (PRC)Completed Study; data analyses ongoing18-125 YearsNCI Genetic
07-C-0100Collection of Blood from Patients with Prostate CancerParticipants currently recruited/enrolled18-125 YearsNCI Genetic
06-M-0214PET Measurement of Regional Rates of Cerebral Protein Synthesis in Subjects with Fragile X SyndromeCompleted Study; data analyses ongoing18-24 YearsNIMH Genetic
06-I-0015Screening Protocol for Genetic Diseases of Lymphocyte Homeostasis and Programmed Cell DeathParticipants currently recruited/enrolled0-125 YearsNIAIDGenetic
06-H-0217Genetic Disorders of Mucociliary ClearanceCompleted Study; data analyses ongoing2-65 YearsNHLBIGenetic
06-H-0190Treatment of T-Large Granular Lymphocyte (T-LGL) Lymphoproliferative Disorders with Alemtuzumab (Campath)Completed Study; data analyses ongoing18-85 YearsNHLBIBone
06-H-0072Atorvastatin as a Disease Modifying Agent in Stage II and III Pulmonary Sarcoidosis: A Randomized, Double-Blind, Placebo-Controlled TrialCompleted Study; data analyses ongoing18-70 YearsNHLBIBone
06-EI-0236National Ophthalmic Genotyping and Phenotyping Network Stage 1 - Creation of DNA Repository for Inherited Ophthalmic DiseasesNo longer recruiting/follow-up only2-125 YearsNEI Genetic
06-C-0213Tissue Procurement Protocol for the Developmental Therapeutics Clinic, National Cancer Institute (NCI)Participants currently recruited/enrolled0-125 YearsNCI Bone
06-C-0134Natural History and Biology of Dermal Neurofibromas in Neurofibromatosis Type 1Completed Study; data analyses ongoing20-99 YearsNCI Genetic
06-C-0014Prospective Evaluation of Genetic and Epigenetic Alterations in Patients with Thoracic MalignanciesParticipants currently recruited/enrolled2-125 YearsNCI Genetic
05-I-0213Screening and Baseline Assessment of Patients with Abnormalities of Immune FunctionParticipants currently recruited/enrolled0-125 YearsNIAIDGenetic
05-H-0130Long-Term Evaluation and Follow Up Care of Patients Treated with Allogeneic Stem Cell TransplantsParticipants currently recruited/enrolled7-80 YearsNHLBIBone
05-CH-0013Adrenal Function in Critical IllnessCompleted Study; data analyses ongoing15-80 YearsNICHDBone
05-C-0252Phase III Randomized Study of R-CHOP v. Dose-Adjusted EPOCH-R with Molecular Profiling in Untreated de Novo Diffuse Large B-Cell LymphomasCompleted Study; data analyses ongoing18-125 YearsNCI Bone
04-HG-0127Clinical and Basic Investigations of Methylmalonic Acidemia (MMA) and Related DisordersParticipants currently recruited/enrolled0-125 YearsNHGRIGenetic
04-H-0012Collection of Blood, Bone Marrow, Urine, and/or Tissue Samples from Patients with Solid Tumors, Hematological Malignancies or Non-Malignant Hematologic Disorders or HLA Compatible Family MembersParticipants currently recruited/enrolled2-125 YearsNHLBIBone
04-CC-0046Citrate Effects and Bone Density Studies in Long-Term Apheresis DonorsCompleted Study; data analyses ongoing18-80 YearsCC Bone
04-C-0281Natural History Study of Clinical and Biological Factors Determining Outcomes in Chronic Graft-Versus-Host DiseaseParticipants currently recruited/enrolled1-125 YearsNCI Rare
04-C-0274Follow-Up Study of Subjects Previously Enrolled in Immunotherapy Studies Utilizing Gene Transfer or Other Immunotherapeutic AgentsParticipants currently recruited/enrolled18-125 YearsNCI Genetic
04-C-0238A Phase 2 Study of 17-Allylamino-17-Demethoxygeldanamycin in Patients with Von Hippel Lindau Disease and Renal TumorsCompleted Study; data analyses ongoing18-125 YearsNCI Rare
04-C-0165Data Collection, Clinical Care and Interventions in CCR, NCIEnrolling by Invitation0-125 YearsNCI Rare
04-C-0102Hematologic Malignancy Biology StudyEnrolling by Invitation1-75 YearsNCI Bone
04-AR-0205Progression of Spinal Fusion in Ankylosing SpondylitisCompleted Study; data analyses ongoing18-125 YearsNIAMSBone
03-N-0164Evaluation and Treatment of Neurosurgical DisordersParticipants currently recruited/enrolled4-125 YearsNINDSGenetic
03-H-0282Characterization of Cardiac Function in Subjects with Hereditary Hemochromatosis Who Are New York Heart Association Functional Class ICompleted Study; data analyses ongoing21-100 YearsNHLBIGenetic
03-H-0170Nonmyeloablative Allogeneic Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation For Severe Congenital Anemias Including Sickle Cell Disease (SCD) and Beta-ThalassemiaParticipants currently recruited/enrolled2-125 YearsNHLBIBone
03-H-0105The Determination of Genetic Basis Of ImmunodeficiencyParticipants currently recruited/enrolled0-125 YearsNHLBIGenetic
03-EI-0033X-Linked Juvenile Retinoschisis - Clinical and Molecular StudiesParticipants currently recruited/enrolled0-125 YearsNEI Genetic
03-E-0099Pathogenic Studies In Families With Twins Or Siblings Discordant For Systemic Rheumatic DisordersCompleted Study; data analyses ongoing2-125 YearsNIEHSGenetic
03-DK-0257Phase II Trial of Effect of Metreleptin Therapy in Severe Insulin ResistanceNo longer recruiting/follow-up only5-125 YearsNIDDKGenetic
03-CC-0060Virtual Function Anatomy (VFA)Participants currently recruited/enrolled5-95 YearsCC Bone
03-C-0066Hereditary Leiomyomatosis Renal Cell Cancer (HLRCC): Identification of the Disease Gene, and Characterization of the Predisposition to Renal CancerParticipants currently recruited/enrolled2-125 YearsNCI Genetic
03-AG-0325The Baltimore Longitudinal Study of Aging(BLSA)Participants currently recruited/enrolled20-125 YearsNIA Bone
02-I-0286Efficacy of Tyrosine Kinase Inhibition in Reducing Eosinophilia in Patients with Myeloid and/or Steroid-Refractory Hypereosinophilic SyndromeParticipants currently recruited/enrolled2-125 YearsNIAIDBone
02-I-0086Evaluation of Viral Factors and Immune Parameters to Study HIV-Specific ImmunityParticipants currently recruited/enrolled18-125 YearsNIAIDGenetic
02-HG-0107Natural History of Glycosphingolipid Storage Disorders and Glycoprotein DisordersParticipants currently recruited/enrolled0-125 YearsNHGRIRare
02-H-0250A Phase I/II Study of HLA-matched Mobilized Peripheral Blood Hematopoietic Stem Cell Transplantation for Advanced Mycosis Fungoides/Sezary Syndrome Using Nonmyeloablative Conditioning with Campath-1HCompleted Study; data analyses ongoing18-125 YearsNHLBIBone
02-DK-0022Long-Term Efficacy of Leptin Replacement in Treatment of LipodystrophyCompleted Study; data analyses ongoing1-125 YearsNIDDKGenetic
02-C-0268Prospective Study of Prophylactic Salpingo-Oophorectomy and Longitudinal CA-125 Screening Among Women at Increased Genetic Risk of Ovarian CancerCompleted Study; data analyses ongoing19-100 YearsNCI Genetic
02-C-0212Clinical, Genetic, Behavioral, Laboratory and Epidemiologic Characterization of Individuals and Families at High Risk of Breast/Ovarian CancerCompleted Study; data analyses ongoing18-100 YearsNCI Genetic
02-C-0211Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of MelanomaParticipants currently recruited/enrolled2-125 YearsNCI Genetic
02-C-0178Multidisciplinary Etiologic Study of Familial Testicular CancerNo longer recruiting/follow-up only12-125 YearsNCI Genetic
01-N-0206Phenotype/Genotype Correlations in Movement DisordersParticipants currently recruited/enrolled2-125 YearsNINDSGenetic
01-I-0238Host Response to Infection and Treatment in Leishmania Infection of HumansParticipants currently recruited/enrolled3-100 YearsNIAIDBone
01-I-0202Natural History, Genetics, Phenotype, and Treatment of Mycobacterial InfectionsParticipants currently recruited/enrolled0-100 YearsNIAIDGenetic
01-H-0122Collection and Storage of Umbilical Cord Hematopoietic Stem Cells for Sickle Cell Disease TherapyParticipants currently recruited/enrolled18-45 YearsNHLBIBone
01-DK-N117Family Investigation of Nephropathy and Diabetes (F.I.N.D.)Clinical hold/Recruitment or enrollment suspended18-125 YearsNIDDKGenetic
01-DC-0229Genetic Analysis of Hereditary Disorders of Hearing and BalanceCompleted Study; data analyses ongoing0-99 YearsNIDCDGenetic
01-DC-0228Clinical and Molecular Analysis of Enlarged Vestibular AqueductsCompleted Study; data analyses ongoing0-99 YearsNIDCDGenetic
01-D-0184A Natural History Study of Bone and Mineral DisordersParticipants currently recruited/enrolled0-125 YearsNIDCRBone
01-C-0129Eligibility Screening for the NIH Intramural Research Program Clinical ProtocolsEnrolling by Invitation0-125 YearsNCI Bone
01-C-0038Collection of Blood, Bone Marrow, Tumor, or Tissue Samples from Patients with HIV Infection, KSHV Infection, Viral-Related Pre-Malignant Lesions, and/or CancerParticipants currently recruited/enrolled18-125 YearsNCI Bone
01-C-0030Short-Course EPOCH - Rituximab in Untreated CD-20+ HIV-Associated LymphomasNo longer recruiting/follow-up only18-125 YearsNCI Bone
01-C-0009Breast Imaging Screening Studies in Women at High Genetic Risk of Breast Cancer: Annual Follow-up StudyCompleted Study; data analyses ongoing18-100 YearsNCI Genetic
01-AR-0227Studies of the Natural History of Rheumatic Disease in Minority CommunitiesParticipants currently recruited/enrolled18-100 YearsNIAMSBone
00-N-0089Genetic Analysis of the Chiari I MalformationCompleted Study; data analyses ongoing1-125 YearsNINDSGenetic
00-M-0085Structural and Functional Imaging of Neuropsychiatric Patients and Normal Volunteers with 3.0 Tesla MRI and Magnetoencephalography (MEG)Participants currently recruited/enrolled18-125 YearsNIMH Genetic
00-HG-0058Genetic Analysis of Attention Deficit Hyperactivity Disorder (ADHD)Completed Study; data analyses ongoing7-125 YearsNHGRIGenetic
00-CH-0160Clinical and Molecular Analysis of ACTH-Independent Steroid Hormone Production in Adrenocortical TissueCompleted Study; data analyses ongoing3-70 YearsNICHDGenetic
00-CH-0093Diagnosis, Pathophysiology, and Molecular Biology of Pheochromocytoma and ParagangliomaParticipants currently recruited/enrolled3-125 YearsNICHDGenetic
00-C-0078Collection of Blood, Fluid, Bone Marrow, Tumor, or Tissue Samples from Patients with Cancer or Normal VolunteersParticipants currently recruited/enrolled18-125 YearsNCI Bone
99-H-0050Non-Myeloablative Allogeneic Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Hematologic Malignancies in High Risk Patients and in Patients with Debilitating Hematologic DiseasesCompleted Study; data analyses ongoing2-80 YearsNHLBIBone
98-D-0145Screening and Natural History of Patients with Polyostotic Fibrous Dysplasia and the McCune-Albright SyndromeParticipants currently recruited/enrolled0-100 YearsNIDCRBone
98-CH-0081Clinical and Basic Investigations into Smith-Lemli-Opitz SyndromeCompleted Study; data analyses ongoing0-125 YearsNICHDGenetic
97-DC-0057Genetic Studies of StutteringCompleted Study; data analyses ongoing6-125 YearsNIDCDGenetic
97-CH-0076A Clinical and Genetic Investigation of Pituitary and HYPOTHALAMIC Tumors and Related DisordersParticipants currently recruited/enrolled3-70 YearsNICHDGenetic
96-H-0100Role of Genetic Factors in the Pathogenesis of Lung DiseaseParticipants currently recruited/enrolled2-90 YearsNHLBIGenetic
96-H-0049Use of Granulocyte Colony Stimulating Factor (G-CSF) Mobilized Leukapheresis Collections from Healthy Volunteers to Develop Improved Methods of Stem Cell and Lymphocyte Selection for Allogeneic TransplantationParticipants currently recruited/enrolled18-60 YearsNHLBIBone
96-CH-0033An Open, Randomized, Long-Term Clinical Trial of Flutamide, Testolactone, and Reduced Hydrocortisone Dose vs. Conventional Treatment of Children with Congenital Adrenal HyperplasiaNo longer recruiting/follow-up only2-18 YearsNICHDBone
95-I-0066Genetic Analysis of Immune DisordersParticipants currently recruited/enrolled0-125 YearsNIAIDGenetic
95-I-0027Virologic and Immunologic Evaluation of Lymph Node, Tonsillar and Intestinal Biopsies, and Bronchoalveolar Lavage FluidParticipants currently recruited/enrolled18-125 YearsNIAIDGenetic
95-HG-0193Clinical and Basic Investigations into Hermansky-Pudlak SyndromeParticipants currently recruited/enrolled0-125 YearsNHGRIGenetic
95-CH-0059Definition of the Genotype and Clinical Phenotype of Primary Pigmented Nodular Adrenocortical Disease (PPNAD), Carney Complex, Peutz-Jeghers Syndrome and Related ConditionsCompleted Study; data analyses ongoing3-70 YearsNICHDGenetic
94-HG-0105An Exploratory Study of the Genetics, Pathophysiology, and Natural History of Autoinflammatory DiseasesParticipants currently recruited/enrolled0-125 YearsNHGRIGenetic
94-E-0165Studies in the Natural History and Pathogenesis of Childhood-Onset and Adult-Onset Idiopathic Inflammatory MyopathiesParticipants currently recruited/enrolled2-100 YearsNIEHSGenetic
94-DK-0133Genetic Markers for Focal Segmental GlomerulosclerosisCompleted Study; data analyses ongoing1-125 YearsNIDDKGenetic
94-C-0074Treatment and Natural History Study of Lymphomatoid GranulomatosisParticipants currently recruited/enrolled12-125 YearsNCI Bone
93-I-0119Detection and Characterization of Host Defense DefectsParticipants currently recruited/enrolled0-125 YearsNIAIDGenetic
92-M-0174The Central Nervous System Effects of Pharmacologically Induced Hypogonadotropic Hypogonadism with and without Estrogen and Progesterone ReplacementCompleted Study; data analyses ongoing18-50 YearsNIMH Genetic
92-I-0125A Study of Viral Burden in Peripheral Blood Versus Lymphoid and Bone Marrow Tissue in HIV-Infected IndividualsParticipants currently recruited/enrolled18-125 YearsNIAIDBone
92-CH-0034Studies of Growth Deficiency and Growth Hormone Treatment in Children with Osteogenesis Imperfecta Types III and IVCompleted Study; data analyses ongoing3-16 YearsNICHDBone
91-I-0140Studies of the Pathogenesis of HIV Infection in Human Peripheral Blood Cells and/or Body Fluids in HIV-Infected and HIV-Uninfected VolunteersParticipants currently recruited/enrolled18-125 YearsNIAIDGenetic
91-AR-0196Studies on the Natural History and Pathogenesis of Polymyositis, Dermatomyositis, and Related DiseasesParticipants currently recruited/enrolled16-125 YearsNIAMSGenetic
90-M-0088The Treatment of Menstrually-Related Mood Disorders with the Gonadotropin Releasing Hormone (GnRH) Agonist, Depot Leuprolide Acetate (Lupron)Completed Study; data analyses ongoing18-45 YearsNIMH Genetic
89-N-0045Evaluation of Progression in Multiple Sclerosis by Magnetic Resonance Imaging (MRI)Participants currently recruited/enrolled18-125 YearsNINDSGenetic
89-M-0006Brain Imaging of Childhood Onset Psychiatric Disorders, Endocrine Disorders and Healthy VolunteersParticipants currently recruited/enrolled3-125 YearsNIMH Genetic
89-I-0158Studies of Immune Regulation in Patients with Common Variable Immunodeficiency and Related Humoral Immunodeficiency SyndromesParticipants currently recruited/enrolled2-125 YearsNIAIDGenetic
89-C-0086Von Hippel-Lindau (VHL): Clinical Manifestations, Diagnosis, Management and Molecular Bases of Inherited Renal and Other Urologic Malignant DisordersParticipants currently recruited/enrolled2-125 YearsNCI Genetic
87-DK-0029Diagnosis and Treatment of Patients with Cystic FibrosisParticipants currently recruited/enrolled4-125 YearsNIDDKGenetic
86-HG-0096Studies of Genetic Heterogeneity in Patients with Lysosomal Storage DisordersEnrolling by Invitation0-125 YearsNHGRIGenetic
85-I-0127Natural History of Treated Neurocysticercosis and Long-Term OutcomesParticipants currently recruited/enrolled3-99 YearsNIAIDBone
85-H-0105Cardiovascular Evaluation of Homozygous Familial HypercholesterolemiaCompleted Study; data analyses ongoing2-70 YearsNHLBIRare
81-M-0126The Evaluation of Women with Menstrually Regulated Mood and Behavioral DisordersParticipants currently recruited/enrolled18-50 YearsNIMH Genetic
81-I-0164Procedures to Obtain Plasma, Lymphocytes, or Other Specimens for Research StudiesParticipants currently recruited/enrolled18-125 YearsNIAIDGenetic
80-M-0083Bipolar Genetics: A Collaborative StudyParticipants currently recruited/enrolled18-125 YearsNIMH Genetic
78-HG-0093Use of Cysteamine in the Treatment of CystinosisParticipants currently recruited/enrolled0-125 YearsNHGRIGenetic
78-C-0039Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of CancerNo longer recruiting/follow-up only0-125 YearsNCI Genetic
77-DK-0096Studies on Thyroid Nodules and Thyroid CancerParticipants currently recruited/enrolled0-125 YearsNIDDKGenetic
77-DK-0002Evaluation of Patients with Thyroid Function DisordersParticipants currently recruited/enrolled0-125 YearsNIDDKGenetic
76-DK-0006Natural History of Disorders of Insulin ResistanceParticipants currently recruited/enrolled0-125 YearsNIDDKGenetic
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