NIH Clinical Center: Search the Studies

Search the Studies

50 Studies found from all possible combinations of your search terms. Select a protocol that you wish to review.

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Protocol Number	Title	Protocol Status	Min-Max Age	Institute	Keywords
001043-I	Evaluating the Genetics and Immunology of Periodic Fever, Aphthous Stomatitis, Pharyngitis, and Cervical Adenitis (PFAPA) Syndrome and Other Tonsil Disorders	Recruitment has not started	0-125 Years	NIAID	Childhood
001018-CH	Establishment of Genomic and Phenotypic Database for Niemann-Pick Disease, Type C	Participants currently recruited/enrolled	0-125 Years	NICHD	Childhood
000908-DK	Peripheral Blood and Urine Immune Cell Phenotyping in Membranous Nephropathy using FACS and Single Cell RNA-seq	Participants currently recruited/enrolled	18-125 Years	NIDDK	Dysregulation
000894-AR	Natural History of Inflammatory Muscle Diseases	Recruitment has not started	12-125 Years	NIAMS	Childhood
000780-D	A Phase 2 Study of Denosumab for Prevention of Skeletal Disease Progression in Children with Fibrous Dysplasia	Participants currently recruited/enrolled	4-14 Years	NIDCR	Childhood
000715-CH	Biorepository in Participants Who Undergo OTC for Gonadotoxic Therapy	Participants currently recruited/enrolled	4-35 Years	NICHD	Childhood
000686-CH	Intrathecal 2-Hydroxypropyl-Beta-Cyclodextrin for Neurological Decline in Patients with Niemann-Pick Disease Type C1	Participants currently recruited/enrolled	18-125 Years	NICHD	Childhood
000585-CH	An Open-label Safety, Pharmacokinetic, and Efficacy Study of Miglustat for the Treatment of CLN3 Disease in Patients 17 Years of Age and Older	Participants currently recruited/enrolled	17-125 Years	NICHD	Childhood
000404-C	A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Subjects with VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) Syndrome	Participants currently recruited/enrolled	18-75 Years	NCI	Dysregulation
000384-I	Analysis of the Immune Response to COVID-19 Vaccination and Outcomes in Individuals With and Without Immune Deficiencies and Dysregulations	Participants currently recruited/enrolled	3-125 Years	NIAID	Dysregulation
22-C-0003	Feasibility of Evaluating Abemaciclib Neuropharmacokinetics of Diffuse Midline Glioma Using Intratumoral Microdialysis	Participants currently recruited/enrolled	18-39 Years	NCI	Childhood
21-C-0021	SARC037: A Phase I/II Study to Evaluate the Safety of Trabectedin Administered as a 1-Hour Infusion in Ewing Sarcoma Patients in Combination with Low Dose Irinotecan and 3'-Deoxy-3'-18F Fluorothymidine (18F-FLT) Imaging	Participants currently recruited/enrolled	6-125 Years	NCI	Childhood
20-CH-0126	Data Collection Study of Pediatric and Adolescent Gynecology Conditions	Participants currently recruited/enrolled	0-125 Years	NICHD	Childhood
20-C-0070	A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Patients with Inborn Errors of Immunity	Participants currently recruited/enrolled	4-69 Years	NCI	Dysregulation
19-CH-0051	Long-Term Follow-UP of Survivors of Pediatric Cushing Disease	Participants currently recruited/enrolled	2-90 Years	NICHD	Childhood
19-C-0085	Phase II Trial of Allogeneic Hematopoietic Cell Transplantation for Peripheral T cell Lymphoma	Clinical hold/Recruitment or enrollment suspended	12-125 Years	NCI	Dysregulation
18-DK-N071	Early Tracking of Childhood Health Determinants Study	Participants currently recruited/enrolled	0-125 Years	NIDDK	Childhood
18-CH-0120	A Natural History of the Collagen-Related Disorder Osteogenesis Imperfecta and the Genotype-Phenotype Correlation	No longer recruiting/follow-up only	0-125 Years	NICHD	Childhood
18-C-0135	Phase II Trial of Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or Dysregulation	Participants currently recruited/enrolled	4-125 Years	NCI	Dysregulation
17-I-0163	Natural History of Intestinal Inflammation in Patients with Primary Immune Dysregulations	Participants currently recruited/enrolled	3-125 Years	NIAID	Dysregulation
17-I-0016	Studies of the Natural History, Pathogenesis, and Outcome of Autoinflammatory Diseases (NOMID/CAPS, DIRA, CANDLE, SAVI, NLRC4-MAS, Still's-like Diseases, and Other Undifferentiated Autoinflammatory Diseases)	Participants currently recruited/enrolled	0-99 Years	NIAID	Dysregulation
17-C-0175	CC-4047-BRN-001: A Phase 2 Clinical Study of Pomalidomide (CC-4047) Monotherapy for Children and Young Adults with Recurrent or Progressive Primary Brain Tumors	Completed Study; data analyses ongoing	3-20 Years	NCI	Childhood
17-C-0049	A Phase I/II Trial of the Insulin-Like Growth Factor 1 Receptor (IGF-1R) Antibody AMG479 (Ganitumab) in Combination with the Src Family Kinase (SFK) Inhibitor Dasatinib in Patients with Embryonal and Alveolar Rhabdomyosarcoma	Completed Study; data analyses ongoing	2-125 Years	NCI	Childhood
17-C-0028	A Pilot Study of Vincristine Sulfate Liposome Injection (Marqibo ) in Combination with Chemotherapy for Children, Adolescents, and Young Adults with Relapse of Acute Lymphoblastic Leukemia	Completed Study; data analyses ongoing	2-21 Years	NCI	Childhood
16-CC-0149	Dopamine and Motor Learning in Cerebral Palsy	Participants currently recruited/enrolled	5-25 Years	CC	Childhood
16-C-0003	Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies	Participants currently recruited/enrolled	4-75 Years	NCI	Dysregulation
15-M-0182	Psychological Treatments for Youth with Severe Irritability	Participants currently recruited/enrolled	8-17 Years	NIMH	Dysregulation
15-AA-0127	(Epi)genetic Modulators of Fear Extinction in Alcohol Dependence	Participants currently recruited/enrolled	21-65 Years	NIAAA	Childhood
13-M-0028	Diagnosis of Childhood-onset Behavioral Disorders, Neuropsychiatric Disorders and Neurodevelopmental Disorders	Participants currently recruited/enrolled	0-99 Years	NIMH	Childhood
12-N-0095	Clinical and Molecular Manifestations of Neuromuscular and Neurogenetic Disorders of Childhood	Participants currently recruited/enrolled	0-125 Years	NINDS	Childhood
12-HG-0202	The Neurobehavioral, Environmental and Genetic Factors Impacting the Clinical Course of Attention Deficit Hyperactivity Disorder	Participants currently recruited/enrolled	3-125 Years	NHGRI	Childhood
12-C-0206	Understanding the Perceived Influence of Childhood Cancer and NF1 on the Parents' Marital/Partner Relationship: A Descriptive Study	Completed Study; data analyses ongoing	18-125 Years	NCI	Childhood
11-N-0051	Surgery as a Treatment for Medically Intractable Epilepsy	Participants currently recruited/enrolled	8-125 Years	NINDS	Childhood
10-M-0112	Defining the Brain Phenotype of Children with Williams Syndrome	Participants currently recruited/enrolled	5-125 Years	NIMH	Childhood
10-C-0086	Comprehensive Omics Analysis of Pediatric Solid Tumors and Establishment of a Repository for Related Biological Studies	Participants currently recruited/enrolled	0-125 Years	NCI	Childhood
07-D-0016	Effects of PTH Replacement on Bone in Hypoparathyroidism	Completed Study; data analyses ongoing	18-70 Years	NIDCR	Childhood
06-CH-0011	Natural History Study of Patients with Excess Androgen	Participants currently recruited/enrolled	0-99 Years	NICHD	Childhood
04-C-0281	Natural History Study of Clinical and Biological Factors Determining Outcomes in Chronic Graft-Versus-Host Disease	Participants currently recruited/enrolled	1-125 Years	NCI	Dysregulation
03-M-0186	The Psychobiology of Temperament: An fMRI Study	Participants currently recruited/enrolled	0-30 Years	NIMH	Childhood
03-C-0278	A Comparative Study of Pediatric CNS Tumor Activity as Assessed by 18F-FDG PET Imaging and Proton Magnetic Resonance Spectroscopic Imaging (1H-MRSI)	Completed Study; data analyses ongoing	1-21 Years	NCI	Childhood
03-AR-0173	Studies of Natural History, Pathogenesis, and Outcomes in Autoimmune and Inflammatory Diseases Including Juvenile Dermatomyositis	Participants currently recruited/enrolled	2-125 Years	NIAMS	Dysregulation
02-M-0021	Characterization and Pathophysiology of Severe Mood and Behavioral Dysregulation in Children and Youth	Participants currently recruited/enrolled	7-60 Years	NIMH	Dysregulation
02-I-0147	Genetic Studies of Chronic Active Epstein-Barr Virus Infection	Participants currently recruited/enrolled	1-125 Years	NIAID	Childhood
00-M-0198	The Phenomenology and Neurophysiology of Affective Dysregulation in Children and Adolescents with Bipolar Disorder	Completed Study; data analyses ongoing	3-58 Years	NIMH	Dysregulation
00-HG-0058	Genetic Analysis of Attention Deficit Hyperactivity Disorder (ADHD)	Completed Study; data analyses ongoing	7-125 Years	NHGRI	Childhood
97-CH-0076	A Clinical and Genetic Investigation of Pituitary and HYPOTHALAMIC Tumors and Related Disorders	Participants currently recruited/enrolled	3-70 Years	NICHD	Childhood
97-CH-0064	Evaluation and Intervention for Ambulation, Growth, and Basilar Invagination in Osteogenesis Imperfecta	Completed Study; data analyses ongoing	0-10 Years	NICHD	Childhood
94-E-0165	Studies in the Natural History and Pathogenesis of Childhood-Onset and Adult-Onset Idiopathic Inflammatory Myopathies	Participants currently recruited/enrolled	2-100 Years	NIEHS	Childhood
89-M-0006	Brain Imaging of Childhood Onset Psychiatric Disorders, Endocrine Disorders and Healthy Volunteers	Participants currently recruited/enrolled	3-125 Years	NIMH	Childhood
88-CH-0032	Specificity of Mother-Infant Interaction: The Influence of Maternal Age, Employment Status, and Parenthood Status	Completed Study; data analyses ongoing	0-23 Years	NICHD	Childhood