Search the Studies

39 Studies found from all possible combinations of your search terms. Select a protocol that you wish to review.
Protocol Number Title Protocol Status Min-Max Age Institute Keywords
000686-CHIntrathecal 2-Hydroxypropyl-Beta-Cyclodextrin for Neurological Decline in Patients with Niemann-Pick Disease Type C1Participants currently recruited/enrolled18-125 YearsNICHDProgressive Palsy
000428-NAn Observational Study to Assess Clinical, Molecular and Imaging Biomarkers in Spinal and Bulbar Muscular Atrophy (SBMA)Participants currently recruited/enrolled18-125 YearsNINDSProgressive Bulbar
17-N-0131Investigating Complex Neurodegenerative Disorders Related to Amyotrophic Lateral Sclerosis and Frontotemporal DementiaParticipants currently recruited/enrolled18-125 YearsNINDSProgressive Palsy
001180-CCA Phase I/II Trial Evaluating Long-Term Use of a Pediatric Robotic Exoskeleton (P.REX/Agilik) to Improve Gait in Children with Movement DisordersRecruitment has not started3-17 YearsCC Palsy
001124-IExpanded Access IND Protocol: Use of Tecovirimat (TPOXX (R)) for Treatment of Human Non-Variola Orthopoxvirus Infections in Adults and ChildrenEnrolling by Invitation0-125 YearsNIAIDProgressive
001018-CHEstablishment of Genomic and Phenotypic Database for Niemann-Pick Disease, Type CParticipants currently recruited/enrolled0-125 YearsNICHDProgressive
000413-HNatural History study of CADASILParticipants currently recruited/enrolled18-100 YearsNHLBIProgressive
000126-NA Pilot Study of NT-I7, a Long-Acting Recombinant IL-7 Molecule, as an Immune Reconstitution Strategy for Lymphopenia in Patients with Progressive Multifocal LeukoencephalopathyParticipants currently recruited/enrolled18-125 YearsNINDSProgressive
000049-HEvaluation of the Safety,Tolerability, Pharmacokinetics, and Pharmacodynamics of Long-term Mitapivat Dosing in Subjects with Stable Sickle Cell Disease: An Extension of a Phase I Pilot Study of MitapivatNo longer recruiting/follow-up only18-70 YearsNHLBIProgressive
21-N-0016Phase I/II Study of Teriflunomide in HTLV-1 Associated Myelopathy/Tropical Spastic ParaparesisParticipants currently recruited/enrolled18-125 YearsNINDSProgressive
20-N-0064An observational study to assess clinical manifestations and biomarkers in amyotrophic lateral sclerosis type 4 and other inherited neurological disorders of RNA processing.Participants currently recruited/enrolled5-125 YearsNINDSProgressive
19-M-0095PET Imaging of Neuroinflammation in Neurodegenerative Diseases via a Novel TSPO RadioligandParticipants currently recruited/enrolled18-125 YearsNIMH Progressive
18-H-0003Discovery of Sirolimus Sensitive Biomarkers in BloodParticipants currently recruited/enrolled18-90 YearsNHLBIProgressive
18-CC-0052Near-infrared Spectroscopy and Electroencephalography to Assess Cortical Activation During Motor Tasks in Infants and Toddlers with or at high-risk for Cerebral Palsy and Autism Spectrum Disorder Compared to Infants and Toddlers with Typical DevelopmentParticipants currently recruited/enrolled0-5 YearsCC Palsy
18-C-0110Safety Run-In and Phase II Trial of M7824 and Topotecan or Temozolomide in Relapsed Small Cell CancersParticipants currently recruited/enrolled18-125 YearsNCI Progressive
17-I-0122NIAID Centralized Sequencing ProtocolParticipants currently recruited/enrolled0-125 YearsNIAIDProgressive
17-I-0083Targeting Residual Activity By Precision, Biomarker-Guided Combination Therapies of Multiple Sclerosis (TRAP-MS)Participants currently recruited/enrolled18-125 YearsNIAIDProgressive
17-C-0175CC-4047-BRN-001: A Phase 2 Clinical Study of Pomalidomide (CC-4047) Monotherapy for Children and Young Adults with Recurrent or Progressive Primary Brain TumorsCompleted Study; data analyses ongoing3-20 YearsNCI Progressive
16-N-0072A Pilot Study of Adoptive Cellular Immunotherapy for Progressive Multifocal Leukoencephalopathy with Ex Vivo Generated Polyomavirus-Specific T-cellsCompleted Study; data analyses ongoing18-125 YearsNINDSProgressive
16-H-0132CADASIL Disease DiscoveryCompleted Study; data analyses ongoing18-100 YearsNHLBIProgressive
16-CC-0149Dopamine and Motor Learning in Cerebral PalsyParticipants currently recruited/enrolled5-25 YearsCC Palsy
15-DK-0170Treatment of Chronic Delta Hepatitis with Lonafarnib and RitonavirCompleted Study; data analyses ongoing18-99 YearsNIDDKProgressive
14-CC-0027The NIH Exercise Therapy for Advanced Lung Disease Trials: Response and Adaptation to Aerobic Exercise in Patients with Interstitial Lung DiseaseParticipants currently recruited/enrolled21-80 YearsCC Progressive
14-C-0037A Phase 2 Study of the MET Kinase Inhibitor INC280 in Papillary Renal Cell CancerCompleted Study; data analyses ongoing18-125 YearsNCI Progressive
14-C-0004A Multicenter Phase 2 Study of the Bruton's Tyrosine Kinase Inhibitor PCI-32765 (Ibrutinib) for Treatment of Relapsed Hairy Cell LeukemiaNo longer recruiting/follow-up only18-125 YearsNCI Progressive
14-C-0001Phase II Study of Axitinib (AG-013736) with Evaluation of the VEGF-pathway in Metastatic, Recurrent or Primary Unresectable Pheochromocytoma/ParagangliomaCompleted Study; data analyses ongoing18-125 YearsNCI Progressive
13-N-0017Natural History Study of Progressive Multifocal Leukoencephalopathy (PML)Participants currently recruited/enrolled2-125 YearsNINDSProgressive
13-H-0051Bronchodilator Effects of Nebulized versus Inhaled Albuterol in Subjects with LymphangioleiomyomatosisParticipants currently recruited/enrolled18-125 YearsNHLBIProgressive
13-CC-0210Evaluating an Extension Assist Knee Ankle Foot Orthosis to Improve Gait in Children with Movement DisordersParticipants currently recruited/enrolled5-125 YearsCC Palsy
13-CC-0110Near-infrared Spectroscopy and Electroencephalography to Assess and Train Cortical Activation During Motor TasksParticipants currently recruited/enrolled5-125 YearsCC Palsy
12-CC-0211A Pilot Study of the Effect of Spironolactone Therapy on Exercise Capacity and Endothelial Dysfunction in Pulmonary Arterial HypertensionParticipants currently recruited/enrolled18-125 YearsCC Progressive
11-M-0251A Longitudinal Investigation of the Endocrine and Neurobiologic Events Accompanying PubertyParticipants currently recruited/enrolled7-35 YearsNIMH Progressive
10-CC-0150Effects of Rapid-Resisted Exercise on Ambulatory Adults with Traumatic Brain InjuryCompleted Study; data analyses ongoing18-44 YearsCC Palsy
08-C-0130A Phase II Trial of Peginterferon alfa-2b (PEG-Intron) for Neurofibromatosis Type 1 Related Unresectable, Symptomatic or Life-Threatening Plexiform NeurofibromasCompleted Study; data analyses ongoing0-21 YearsNCI Progressive
06-I-0153A Pilot Study of Hepatic Fibrosis in HIV/AIDS Patients with Chronically Elevated Transaminases on Antiretroviral TherapyNo longer recruiting/follow-up only18-100 YearsNIAIDProgressive
06-CH-0186Evaluation of Biochemical Markers and Clinical Investigation of Niemann-Pick Disease, Type CParticipants currently recruited/enrolled0-125 YearsNICHDProgressive
94-HG-0132The Phenotype and Etiology of Proteus SyndromeParticipants currently recruited/enrolled0-125 YearsNHGRIProgressive
92-I-0125A Study of Viral Burden in Peripheral Blood Versus Lymphoid and Bone Marrow Tissue in HIV-Infected IndividualsParticipants currently recruited/enrolled18-125 YearsNIAIDProgressive
77-DK-0096Studies on Thyroid Nodules and Thyroid CancerParticipants currently recruited/enrolled0-125 YearsNIDDKProgressive
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