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231 Studies found from all possible combinations of your search terms. Select a protocol that you wish to review.
Protocol Number Title Protocol Status Min-Max Age Institute Keywords
000206-CHEndometrial Basis for Infertility in Women with Recurrent Implantation Failure and Pregnancy LossParticipants currently recruited/enrolled18-42 YearsNICHDPregnancy Loss Recurrent
21-C-0013A Phase I/II Study of Adjuvant PRGN-2012 in Adult Patients with Recurrent Respiratory PapillomatosisParticipants currently recruited/enrolled18-125 YearsNCI Pregnancy Recurrent
20-C-0069A First-In-Human Phase I Single-Agent Dose-Escalation, Food Effect and Dose Expansion Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System NeoplasmsParticipants currently recruited/enrolled18-125 YearsNCI Pregnancy Recurrent
19-C-0041Birinapant and Intensity Modulated Re-Irradiation Therapy (IMRRT) for Locoregionally Recurrent Head and Neck Squamous Cell Carcinoma (HNSCC)Participants currently recruited/enrolled18-125 YearsNCI Pregnancy Recurrent
19-C-0023A Phase II Study of Olaparib (AZD2281) in Patients with Metastatic/Advanced Urothelial Carcinoma and other genitourinary tumors with DNA-Repair DefectsParticipants currently recruited/enrolled18-125 YearsNCI Pregnancy Loss
17-N-0055Functional Connectivity as a Biomarker of rTMSCompleted Study; data analyses ongoing18-125 YearsNINDSPregnancy Loss
08-I-0184Studies in the Pathogenesis of AnaphylaxisParticipants currently recruited/enrolled13-75 YearsNIAIDLoss Recurrent
08-DK-N140Predicting Adaptive ThermogenesisCompleted Study; data analyses ongoing18-60 YearsNIDDKPregnancy Loss
001146-IA Repository to Study Host-Microbiome Interactions in Health and DiseaseParticipants currently recruited/enrolled0-125 YearsNIAIDPregnancy
001126-DCCollection of Clinical Data and Specimens for Research in Hearing, Balance and Communication DisordersParticipants currently recruited/enrolled2-125 YearsNIDCDLoss
000957-HGA Phase 1/2, Open-Label, Single Dose Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of SEL-302 (MMA-101 following administration of SEL-110) in Pediatric Subjects with Mut Subtype Isolated Methylmalonic Acidemia (MMA)Participants currently recruited/enrolled3-17 YearsNHGRIRecurrent
000861-IA Phase 2 Open-Label Study to Evaluate the Efficacy and Safety of Ruxolitinib on Hair Regrowth in Patients with Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy (APECED)-Associated Alopecia AreataParticipants currently recruited/enrolled12-65 YearsNIAIDLoss
000860-CA Phase I/II Study of Zotiraciclib for Recurrent High-Grade Gliomas with Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) MutationsParticipants currently recruited/enrolled18-125 YearsNCI Recurrent
000827-ARNatural History and Pathogenesis of Alopecia in Children and AdultsParticipants currently recruited/enrolled2-45 YearsNIAMSLoss
000757-DKNatural History of Pregnancy and Pregnancy Outcomes in Metreleptin-Treated vs Untreated Subjects with LipodystrophyParticipants currently recruited/enrolled0-125 YearsNIDDKPregnancy
000696-CA Phase III, Multicenter, International Study with a Parallel, Randomized, Double-blind, Placebo-controlled, 2 Arm Design to Assess the Efficacy and Safety of Selumetinib in Adult Participants with NF1 who have Symptomatic, Inoperable Plexiform NeurofibrParticipants currently recruited/enrolled18-120 YearsNCI Pregnancy
000686-CHIntrathecal 2-Hydroxypropyl-Beta-Cyclodextrin for Neurological Decline in Patients with Niemann-Pick Disease Type C1Participants currently recruited/enrolled18-125 YearsNICHDLoss
000628-CA Study of Prospective Monitoring of Subjects with Biochemically Recurrent Prostate Cancer Using 18F-DCFPyLParticipants currently recruited/enrolled18-125 YearsNCI Recurrent
000612-CPhase 1 Study of NT-I7 (rhIL-7-hyFc) for the Treatment of Kaposi Sarcoma in Patients With or Without Infection with HIVParticipants currently recruited/enrolled18-125 YearsNCI Pregnancy
000596-CPhase II Study of Olaparib in Subjects with Advanced Pancreatic Acinar Cell CarcinomaParticipants currently recruited/enrolled18-125 YearsNCI Pregnancy
000580-CA Phase 1/2, Open Label Dose-Escalation and Expansion Trial of Nkt2152, an Orally Administered Hif2a Inhibitor, to Investigate Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity in Patients with Advanced Clear Cell Renal Cell CarcinomaParticipants currently recruited/enrolled18-125 YearsNCI Recurrent
000527-MCNS Correlates of Extended Sleep RestrictionParticipants currently recruited/enrolled18-39 YearsNIMH Loss
000518-CCObservational Study of Dietary Intake and Dietary Behaviors in Adults with Sickle Cell DiseaseParticipants currently recruited/enrolled18-125 YearsCC Pregnancy
000484-CRandomized Phase II Trial of Durvalumab (D) plus Olaparib (O) and Cediranib (C: DOC) Compared to OC or DC or Chemotherapy in Platinum-Resistant Recurrent Ovarian Cancer with Prior BevacizumabParticipants currently recruited/enrolled18-125 YearsNCI Recurrent
000476-EThe Investigation of Vitamin D and Menstrual Cycles Trial: A Phase II Clinical trialParticipants currently recruited/enrolled19-40 YearsNIEHSPregnancy
000462-CPhase 2, Open-label, Single-arm, Window of Opportunity Study of ASP-1929 Photoimmunotherapy with Fluorescence Imaging in Patients With Operable Primary or Recurrent Head and Neck or Cutaneous Squamous Cell CarcinomaParticipants currently recruited/enrolled18-125 YearsNCI Recurrent
000444-HVaccine Responses in Patients with B Cell MalignanciesParticipants currently recruited/enrolled18-125 YearsNHLBIPregnancy
000414-CHPilot Study of an Optic-to-Audio Device in a Pediatric Cohort with CLN3-related Conditions or Low VisionParticipants currently recruited/enrolled6-18 YearsNICHDLoss
000410-IVRC 325 (000410): A Phase I Open-Label Clinical Trial to Evaluate the Dose, Safety, Tolerability and Immunogenicity of Mosaic Quadrivalent Influenza Vaccine with and without Adjuplex Compared with a Licensed Inactivated Seasonal QIV, In Healthy AdultsParticipants currently recruited/enrolled18-50 YearsNIAIDPregnancy
000392-IMetabolic Profiling of Immune Responses in Immune-Mediated DiseasesParticipants currently recruited/enrolled18-75 YearsNIAIDPregnancy
000387-HThe Natural History of Acquired and Inherited Bone Marrow Failure Syndromes.Participants currently recruited/enrolled2-125 YearsNHLBIPregnancy
000324-CPhase 1/2 Dose Escalation Study of CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults with Recurrent or Refractory CD19/CD22-expressing B Cell MalignanciesParticipants currently recruited/enrolled3-35 YearsNCI Recurrent
000317-CA Phase II, Open-Label Trial of PT-112 in Subjects with Thymoma and Thymic CarcinomaParticipants currently recruited/enrolled18-125 YearsNCI Recurrent
000307-CPhase II Study Evaluating the Efficacy of M9241 in Combination with Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects with Metastatic Colorectal Cancer or Intrahepatic CholangiocarcinomaParticipants currently recruited/enrolled18-125 YearsNCI Pregnancy
000268-CCNIH Intramural Research Program's Pregnancy Registry Protocol for Subjects and Their PartnersEnrolling by Invitation0-100 YearsCC Pregnancy
000241-CHPhase II Trial of Liraglutide (Saxenda(R), Novo Nordisk) in Adolescents with Obesity After Sleeve Gastrectomy: A Pilot Open-Label StudyParticipants currently recruited/enrolled12-20 YearsNICHDLoss
000236-IA Phase 1 Study of Empagliflozin as Treatment for Severe Congenital Neutropenia Due to G6PC3 DeficiencyParticipants currently recruited/enrolled18-125 YearsNIAIDPregnancy
000137-CHImplications of Maternal 45,X Mosaicism As A Secondary Genomic Finding Following Cell-free DNA Sequencing During Pregnancy: A Deep Phenotype StudyRecruitment has not started18-99 YearsNICHDPregnancy
000115-CA Trial of the Safety and Immunogenicity of the COVID-19 Vaccine (mRNA-1273) in Participants with Hematologic Malignancies and Various Regimens of Immunosuppression, and in Participants with Solid Tumors on PD1/PDL1 Inhibitor Therapy, Including Booster DParticipants currently recruited/enrolled18-125 YearsNCI Pregnancy
000110-HA Phase II Study Evaluating Fostamatinib for Hospitalized Adults with COVID-19Completed Study; data analyses ongoing18-125 YearsNHLBIPregnancy
000106-CHGonadal Tissue Freezing for Fertility Preservation in Individuals at risk for Ovarian Dysfunction and Premature Ovarian InsufficiencyParticipants currently recruited/enrolled4-21 YearsNICHDLoss
000096-CA Phase II study of Immunotherapy Combination: Irradiated PD-L1 CAR-NK cells plus Pembrolizumab plus N-803 for Subjects with Recurrent/Metastatic Gastric or Head and Neck CancerParticipants currently recruited/enrolled18-125 YearsNCI Recurrent
000070-HGGenomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African-Americans Study(GENE-FORECAST): Sodium Intervention Trial (SIT)/GENE-FORECAST SITParticipants currently recruited/enrolled21-125 YearsNHGRIPregnancy
000064-IA Phase 1/2 Open-label Study to Evaluate the Safety and Efficacy of Tofacitinib for Chronic Granulomatous Disease with Inflammatory ComplicationsEnrolling by Invitation18-125 YearsNIAIDPregnancy
000030-CPhase 2 Study of Bintrafusp alfa in Recurrent/Metastatic Olfactory Neuroblastoma (BARON).Participants currently recruited/enrolled18-125 YearsNCI Recurrent
22-C-0005Phase I Dose Escalation and Expansion Study of Tazemetostat in Combination with Topotecan and Pembrolizumab in Recurrent Small Cell Lung CancerParticipants currently recruited/enrolled18-125 YearsNCI Recurrent
22-C-0003Feasibility of Evaluating Abemaciclib Neuropharmacokinetics of Diffuse Midline Glioma Using Intratumoral MicrodialysisParticipants currently recruited/enrolled18-39 YearsNCI Recurrent
21-HG-0020Caregiving Networks Across Disease Context and the Life Course: A Comparative Longitudinal StudyParticipants currently recruited/enrolled18-125 YearsNHGRILoss
21-DC-0002Phase III Interventional Study using Atorvastatin to Reduce Cisplatin-Induced Hearing Loss among Individuals with Head and Neck CancerRecruitment has not started18-125 YearsNIDCDLoss
20-N-0064An observational study to assess clinical manifestations and biomarkers in amyotrophic lateral sclerosis type 4 and other inherited neurological disorders of RNA processing.Participants currently recruited/enrolled5-125 YearsNINDSPregnancy
20-M-0157PET Imaging of Cyclooxygenase in Participants with Major Depressive Disorder (MDD)Participants currently recruited/enrolled18-70 YearsNIMH Pregnancy
20-I-0140A Double-Blind, Randomized, Placebo-Controlled, Phase 1, Single-Dose, Dose-Escalating Trial of Long-Acting Recombinant Human IL-7 (NT-I7) for COVID-19Participants currently recruited/enrolled19-75 YearsNIAIDPregnancy
20-I-0123A Longitudinal Study of COVID-19 Sequelae and ImmunityParticipants currently recruited/enrolled18-125 YearsNIAIDPregnancy
20-I-0096VRC 611: A Phase 1 Safety and Pharmacokinetic Study to Evaluate a Human Monoclonal Antibody (mAb) VRC-HIVMAB0102-00-AB (CAP256V2LS) Administered via Subcutaneous and Intravenous Injection in Healthy AdultsNo longer recruiting/follow-up only18-60 YearsNIAIDPregnancy
20-I-0088An Open-label Efficacy and Safety Study of Pozelimab in Patients with CD55 deficient Protein-losing Enteropathy (CHAPLE Disease)Participants currently recruited/enrolled3-125 YearsNIAIDPregnancy
20-I-0084Sample Collection for Systems Evaluation of Patients with Unknown or Incompletely Characterized Immune DefectsParticipants currently recruited/enrolled2-125 YearsNIAIDPregnancy
20-H-0029An Intravenous, Open-Label, Dose Escalation Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Fx-5A in Healthy VolunteersParticipants currently recruited/enrolled18-125 YearsNHLBIPregnancy
20-EI-0163Oral Metformin for Treatment of ABCA4 RetinopathyParticipants currently recruited/enrolled12-125 YearsNEI Loss
20-EI-0052A Phase I/IIa Trial for Autologous Transplantation of Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium for Geographic Atrophy Associated with Age-Related Macular DegenerationParticipants currently recruited/enrolled55-125 YearsNEI Loss
20-DK-0168LYNC-LD Prospective Multicenter Natural History Study of Lipodystrophy Syndromes to Determine Prevalence, Incidence and Predictors of Diabetes and Severe Hypertriglyceridemia, and their Complications.Participants currently recruited/enrolled3-125 YearsNIDDKLoss
20-DK-0079A Randomized, Double-Blinded, Placebo-Controlled Study of REGN4661, A Leptin Receptor Agonist Antibody, In Patients with Generalized LipodystrophyNo longer recruiting/follow-up only12-125 YearsNIDDKLoss
20-DC-0047Natural History of Autosomal Dominant Hearing LossParticipants currently recruited/enrolled3-99 YearsNIDCDLoss
20-C-0142A Phase II Study of Bintrafusp alfa (M7824) in Checkpoint Inhibitor Naive and Refractory Subjects with Urothelial CarcinomaCompleted Study; data analyses ongoing18-125 YearsNCI Pregnancy
20-C-0121Rapid Analysis and Response Evaluation of Combination Anti-Neoplastic Agents in Rare Tumors (RARE CANCER) Trial: RARE 1 Nilotinib and PaclitaxelParticipants currently recruited/enrolled18-125 YearsNCI Pregnancy
20-C-0097A Phase II, Open-Label Trial of Bintrafusp Alfa (M7824) in Subjects with Thymoma and Thymic CarcinomaParticipants currently recruited/enrolled18-125 YearsNCI Recurrent
20-C-0020Ex-Vivo Trial of En-bloc Transurethral Resection of Bladder Tumor (En-bloc TURBT) Specimens Using a Redesigned Surgical Resectoscope DeviceParticipants currently recruited/enrolled18-125 YearsNCI Pregnancy
20-C-0010Phase II Trial of Radium-223 in Biochemically Recurrent Prostate CancerParticipants currently recruited/enrolled18-125 YearsNCI Recurrent
20-AA-0057The Effect of Acute Alcohol Intoxication on Neural Processes During Decisions to Engage in HIV Risk BehaviorsParticipants currently recruited/enrolled21-65 YearsNIAAAPregnancy
19-N-0081A Traveling Subject Study of Replicability in Conventional and Advanced MRI MS BiomarkersCompleted Study; data analyses ongoing18-125 YearsNINDSPregnancy
19-N-0036Exploring the Relationship Between Brain Asymmetry and AttentionCompleted Study; data analyses ongoing18-35 YearsNINDSPregnancy
19-M-0073Safety and Feasibility of Individualized Low Amplitude Seizure Therapy (iLAST)Participants currently recruited/enrolled22-70 YearsNIMH Loss
19-M-0054Mapping the Phenotype in Adults with Phelan-McDermid SyndromeCompleted Study; data analyses ongoing0-125 YearsNIMH Loss
19-I-0069Phase I Open-Label Study of Safety and Immunogenicity of AD4-HIV Envelope Vaccine Vectors in Healthy VolunteersParticipants currently recruited/enrolled18-65 YearsNIAIDPregnancy
19-H-0001Response to the SHINGRIX Varicella Zoster Virus (VZV) Vaccine in Chronic Lymphocytic Leukemia (CLL) Patients that are Treatment Na(SqrRoot) ve or Receiving Bruton s-tyrosine Kinase Inhibitor (BTK-I) TherapyNo longer recruiting/follow-up only18-125 YearsNHLBIPregnancy
19-DK-0067Effect of Low Fat versus Low Carbohydrate Diets on Energy MetabolismCompleted Study; data analyses ongoing18-50 YearsNIDDKLoss
19-C-0117A Phase 1 / 2 Single Arm Open-label Clinical Trial of Gavocabtagene Autoleucel (gavo-cel) in Patients with Advanced Mesothelin Expressing CancerParticipants currently recruited/enrolled18-120 YearsNCI Recurrent
19-C-0006Phase II Trial Evaluating Nivolumab In Patients With IDH-Mutant Gliomas With And Without Hypermutator PhenotypeParticipants currently recruited/enrolled18-125 YearsNCI Pregnancy
18-N-0133Feasibility of Endosphenoidal Coil Placement for Imaging of the Sella During Transsphenoidal SurgeryParticipants currently recruited/enrolled18-125 YearsNINDSPregnancy
18-I-0105VRC 609: A Phase I, Open-Label, Dose-Escalation Study of the Safety and Pharmacokinetics of a Human Monoclonal Antibody, VRC-HIVMAB091-00-AB (N6LS), Administered Intravenously or Subcutaneously with or without Recombinant Human Hyaluronidase PH20 (rHuPH2Completed Study; data analyses ongoing18-50 YearsNIAIDPregnancy
18-I-0092A Phase 2, Open-Label Study to Assess the Immunogenicity of the 9-Valent Human Papillomavirus Recombinant Vaccine in Patients with Idiopathic CD4 T cell LymphocytopeniaParticipants currently recruited/enrolled18-70 YearsNIAIDPregnancy
18-I-0041Investigating the Mechanistic Biology of Primary Immunodeficiency DisordersParticipants currently recruited/enrolled0-75 YearsNIAIDPregnancy
18-I-0039Challenge Infection of Healthy Adult Volunteers with RSV A2Completed Study; data analyses ongoing18-50 YearsNIAIDPregnancy
18-I-0030VRC 603: A Phase 1 Dose-Escalation Study of the Safety of AAV8-VRC07 (VRC-HIVAAV070-00-GT) Recombinant AAV Vector Expressing VRC07 HIV-1 Neutralizing Antibody in Antiretroviral-Treated, HIV-1 Infected Adults with Controlled ViremiaNo longer recruiting/follow-up only18-65 YearsNIAIDPregnancy
18-H-0019Effect of Dietary Omega-7 Palmitoleic Acid-Rich Oil on Lipoprotein Metabolism and Satiety in AdultsParticipants currently recruited/enrolled18-125 YearsNHLBIPregnancy
18-EI-0068An Investigation of Vitamin A Palmitate Supplementation in Patients with Reticular Pseudodrusen (RPD) and Delayed Dark AdaptationParticipants currently recruited/enrolled50-125 YearsNEI Loss
18-EI-0067An Investigation of Vitamin A Palmitate Supplementation in Patients with Age-Related Macular Degeneration (and without reticular pseudodrusen) and Delayed Dark AdaptationParticipants currently recruited/enrolled50-125 YearsNEI Loss
18-EI-0055A Phase III Multicenter Randomized Sham Controlled Study to Determine the Safety and Efficacy of NT-501 in Macular Telangiectasia Type 2Completed Study; data analyses ongoing21-80 YearsNEI Pregnancy
18-DK-N071Early Tracking of Childhood Health Determinants StudyParticipants currently recruited/enrolled0-125 YearsNIDDKPregnancy
18-DK-0123Treatment of Chronic Delta Hepatitis with Lonafarnib, Ritonavir and Lambda InterferonCompleted Study; data analyses ongoing18-125 YearsNIDDKPregnancy
18-DK-0044Effect of Ultra Processed versus Unprocessed Diets on Energy IntakeCompleted Study; data analyses ongoing18-50 YearsNIDDKPregnancy
18-DA-N053Imaging Biomarker for Addiction Treatment OutcomeParticipants currently recruited/enrolled21-125 YearsNIDA Pregnancy
18-DA-N042Understanding the Acute Modulation of Brain Activity by Transcranial Magnetic StimulationParticipants currently recruited/enrolled18-60 YearsNIDA Pregnancy
18-D-0121Natural History of Chronic Graft-versus-Host Disease in the Oral Cavity of Patients Following Allogeneic Hematopoietic Stem Cell Transplant and Including Healthy ControlsParticipants currently recruited/enrolled18-100 YearsNIDCRPregnancy
18-CC-0117PET Imaging of the Dopaminergic and Serotonergic Systems in Treated HIV Positive SubjectsCompleted Study; data analyses ongoing18-70 YearsCC Pregnancy
18-CC-0087Impact of Weekly Administration of Rifapentine and Isoniazid on Steady State Pharmacokinetics of Tenofovir Alafenamide in Healthy VolunteersCompleted Study; data analyses ongoing18-65 YearsCC Pregnancy
18-CC-0013A Randomized, Double-Blind, Placebo-Controlled Study of a Single Dose of Pembrolizumab in HIV-Infected PatientsParticipants currently recruited/enrolled18-99 YearsCC Pregnancy
18-C-0125A Phase I Clinical Trial of T cells Expressing a Novel Fully-human Anti-BCMA CAR for Treating Multiple MyelomaNo longer recruiting/follow-up only18-73 YearsNCI Pregnancy
18-C-0110Safety Run-In and Phase II Trial of M7824 and Topotecan or Temozolomide in Relapsed Small Cell CancersParticipants currently recruited/enrolled18-125 YearsNCI Recurrent
18-C-0102Pilot Study of the MEK1/2 Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) for Adults with Neurofibromatosis Type 1 (NF1) and Cutaneous Neurofibromas (cNF)Completed Study; data analyses ongoing18-125 YearsNCI Pregnancy
18-C-0059Phase 1 Dose Escalation Study of CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults with Recurrent or Refractory CD19/CD22-expressing B Cell MalignanciesParticipants currently recruited/enrolled3-39 YearsNCI Recurrent
18-C-0058A Pilot Study to Evaluate the Effects of Castration on the Pharmacokinetics of Zolpidem After Single Dose Administration in Men with Prostate Cancer Undergoing Androgen Deprivation Therapy Compared to Normal Healthy FemalesParticipants currently recruited/enrolled18-125 YearsNCI Pregnancy
18-C-0034A Phase 2 Study of ONC201 in Recurrent/Refractory Metastatic Breast Cancer and Advanced Endometrial CarcinomaCompleted Study; data analyses ongoing18-125 YearsNCI Recurrent
18-C-0026A Phase 2 Study of Inotuzumab Ozogamicin (NSC# 772518, IND#133494) in Children and Young Adults with Relapsed or Refractory CD22+ B-Acute Lymphoblastic Leukemia (B-ALL)Participants currently recruited/enrolled1-21 YearsNCI Pregnancy
18-C-0014Phase I Trial of 5-aza-4'-thio-2'-Deoxycytidine (Aza-TdC) in Patients with Advanced Solid TumorsParticipants currently recruited/enrolled18-120 YearsNCI Pregnancy
18-C-0005Phase II Trial of Combination Immunotherapy in Biochemically Recurrent Prostate CancerParticipants currently recruited/enrolled18-125 YearsNCI Recurrent
18-AA-0098Investigating a Response Modulation Hypothesis of Socioemotional Processing associated with Alcohol Use DisorderParticipants currently recruited/enrolled21-65 YearsNIAAAPregnancy
17-I-0101An Open-Label, Proof of Concept Study of Vorinostat for the Treatment of Moderate-to-Severe Crohn's Disease and Maintenance Therapy with UstekinumabParticipants currently recruited/enrolled18-65 YearsNIAIDLoss
17-H-0146Prospective Multicenter Registry On Radiation Dose Estimates of Cardiac CT Angiography in Daily Practice in 2017 (PROTECTION VI)Completed Study; data analyses ongoing18-100 YearsNHLBIPregnancy
17-EI-0112A Long-term Follow-up Study of Participants Enrolled in 11-EI-0147: Longitudinal Investigation of Dark Adaptation in Participants with Age-Related Macular Degeneration (DA_AMD)Participants currently recruited/enrolled50-125 YearsNEI Loss
17-EI-0008The Natural History of Geographic Atrophy Associated with Age-Related Macular DegenerationParticipants currently recruited/enrolled55-125 YearsNEI Loss
17-DK-0013Therapeutic Targets in African-American Youth with Type 2 DiabetesParticipants currently recruited/enrolled12-25 YearsNIDDKPregnancy
17-DC-0138Observational Study of Hearing Loss and the Effects of Statin Drugs in Head and Neck Squamous Cell Carcinoma Patients Treated with Cisplatin ChemoradiationCompleted Study; data analyses ongoing18-125 YearsNIDCDLoss
17-CH-0014Pilot Study of Mobile Attention Training in Overweight Female AdolescentsParticipants currently recruited/enrolled12-21 YearsNICHDLoss
17-C-0175CC-4047-BRN-001: A Phase 2 Clinical Study of Pomalidomide (CC-4047) Monotherapy for Children and Young Adults with Recurrent or Progressive Primary Brain TumorsCompleted Study; data analyses ongoing3-20 YearsNCI Recurrent
17-C-0153Phase I Trial of Image Guided Focally Dose Escalated Prostate SBRT for Locally Recurrent Prostate Cancer after Prior RadiotherapyParticipants currently recruited/enrolled18-125 YearsNCI Recurrent
17-C-0125Phase 2 Trial of Nivolumab in Epstein-Barr Virus (EBV)-Positive Lymphoproliferative Disorders and EBV-Positive Non-Hodgkin LymphomasParticipants currently recruited/enrolled12-125 YearsNCI Pregnancy
17-C-010918F-DCFPyL PET/CT in High Risk and Recurrent Prostate CancerEnrolling by Invitation18-125 YearsNCI Recurrent
17-C-0102Phase II Trial of the Immune Checkpoint Inhibitor Nivolumab in Patients with Recurrent Select Rare CNS CancersParticipants currently recruited/enrolled18-99 YearsNCI Recurrent
17-C-0074A Phase 2 Study of Anti-PD-L1 Antibody Atezolizumab in Alveolar Soft Part SarcomaParticipants currently recruited/enrolled2-125 YearsNCI Pregnancy
17-C-0061Phase II Trial of Pembrolizumab in Recurrent or Metastatic Medullary Thyroid CancerCompleted Study; data analyses ongoing18-125 YearsNCI Recurrent
17-C-0037Phase II Trial of LB100, a Protein Phosphatase 2A Inhibitor, in Recurrent GlioblastomaParticipants currently recruited/enrolled18-125 YearsNCI Recurrent
17-C-0011Phase 1 Study of Intraperitoneal Infusion of Autologous Monocytes with Sylatron (Peginterferon alfa-2b) and Actimmune (Interferon gamma-1b) in Women with Recurrent or Refractory Ovarian Cancer, Fallopian Tube Cancer or Primary Peritoneal CancerCompleted Study; data analyses ongoing18-125 YearsNCI Recurrent
17-C-0009Phase I Trial of Zotiraciclib (TG02) Plus Dose-Dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of Zotiraciclib (TG02) plus Temozolomide versus Temozolomide alone in Adults with Recurrent Anaplastic Astrocytoma and GlioblastomaCompleted Study; data analyses ongoing18-125 YearsNCI Recurrent
16-N-0170Effects of Prism Adaption and rTMS on Brain Connectivity and Visual RepresentationCompleted Study; data analyses ongoing18-75 YearsNINDSPregnancy
16-N-0064Cholinergic Receptor Imaging in DystoniaCompleted Study; data analyses ongoing18-125 YearsNINDSPregnancy
16-N-0031An All-Night Functional Magnetic Resonance Imaging Sleep Study With Auditory StimuliParticipants currently recruited/enrolled18-34 YearsNINDSPregnancy
16-I-0165An open-label, non-randomized extension study to evaluate the long term safety, tolerability, efficacy and pharmacokinetics of CDZ173 (leniolisib) in patients with APDS/PASLI (Activated phosphoinositide 3-kinase delta syndrome/p110 delta-activating mutatNo longer recruiting/follow-up only12-75 YearsNIAIDRecurrent
16-H-0132CADASIL Disease DiscoveryCompleted Study; data analyses ongoing18-100 YearsNHLBILoss
16-H-0129Study to Evaluate the Effect of Nicotinamide Riboside on ImmunityCompleted Study; data analyses ongoing18-39 YearsNHLBIPregnancy
16-EI-0169A Pilot Study to Investigate Ustekinumab (STELARA) for the Treatment of Active Sight-Threatening UveitisCompleted Study; data analyses ongoing18-125 YearsNEI Loss
16-EI-0090Natural History of Spinocerebellar Ataxia Type 7 (SCA7)Participants currently recruited/enrolled12-125 YearsNEI Loss
16-EI-0046Uveitis/Intraocular Inflammatory Disease Biobank (iBank)No longer recruiting/follow-up only8-125 YearsNEI Loss
16-EI-0024Rod and Cone Mediated Function in Retinal DiseaseParticipants currently recruited/enrolled5-125 YearsNEI Loss
16-E-0157CaREFREE Study (Calorie Restriction, Environment and Fitness: Reproductive Effects Evaluation Study)Completed Study; data analyses ongoing18-28 YearsNIEHSLoss
16-DK-0173MEASuRE: Metreleptin Effectiveness and Safety RegistryParticipants currently recruited/enrolled0-125 YearsNIDDKPregnancy
16-DA-0080A Novel Compound for Alcoholism Treatment: a Translational Strategy - Part IICompleted Study; data analyses ongoing18-70 YearsNIDA Pregnancy
16-CC-0112Impact of Once-Weekly Rifapentine and Isoniazid on the Steady State Pharmacokinetics of Dolutegravir and Darunavir Boosted with Cobicistat in Healthy VolunteersCompleted Study; data analyses ongoing18-65 YearsCC Pregnancy
16-C-0088A Randomized Phase II/III Study of the Combination of Cediranib and Olaparib Compared to Cediranib or Olaparib Alone, or Standard of Care Chemotherapy in Women with Recurrent Platinum-Resistant or -Refractory Ovarian, Fallopian Tube, or Primary PeritoneaCompleted Study; data analyses ongoing18-125 YearsNCI Recurrent
16-C-0081A Phase I Dose Escalation Trial of Re-Irradiation in Good Prognosis Recurrent GlioblastomaNo longer recruiting/follow-up only18-125 YearsNCI Recurrent
16-C-0073A Phase 2 Study of Olaparib and Cediranib for the Treatment of Recurrent Ovarian CancerCompleted Study; data analyses ongoing18-125 YearsNCI Recurrent
16-C-0035Prostvac in Patients with Biochemically Recurrent Prostate CancerNo longer recruiting/follow-up only18-125 YearsNCI Recurrent
16-C-0034A Phase II Trial of Oral Pazopanib plus Oral Topotecan Metronomic Antiangiogenic Therapy for Recurrent Glioblastoma Multiforme (A) without Prior Bevacizumab Exposure and (B) after Failing Prior BevacizumabCompleted Study; data analyses ongoing18-125 YearsNCI Recurrent
16-C-0011A Phase I-II Trial of Everolimus and Sorafenib in Patients with Recurrent High-Grade GliomasCompleted Study; data analyses ongoing18-125 YearsNCI Recurrent
16-C-0009Phase II Trial of Carboplatin and Bevacizumab for the Treatment of Recurrent Low-Grade and Anaplastic Supratentorial, Infratentorial and Spinal Cord Ependymoma in Adults: A Multi-Center TrialCompleted Study; data analyses ongoing18-125 YearsNCI Recurrent
15-M-0066Influence on Plasticity of Brain TemperatureParticipants currently recruited/enrolled18-50 YearsNIMH Pregnancy
15-HG-0049Maternal Inborn Errors of Metabolism in Pregnancy: A Pregnancy Registry ProtocolCompleted Study; data analyses ongoing14-50 YearsNHGRIPregnancy
15-H-0017Characterization of Apolipoprotein A-I Pathways in Idiopathic Pulmonary FibrosisCompleted Study; data analyses ongoing18-100 YearsNHLBIPregnancy
15-E-0134NIEHS EPA Pilot Study of Exposure to Chemicals in Consumer ProductsCompleted Study; data analyses ongoing35-74 YearsNIEHSPregnancy
15-E-0058Natural History of Asthma with Longitudinal Environmental SamplingParticipants currently recruited/enrolled18-60 YearsNIEHSPregnancy
15-DK-0192Quantifying Weight Regain and the Persistence of Metabolic Adaptation Following Extreme Weight LossCompleted Study; data analyses ongoing18-125 YearsNIDDKLoss
15-C-0205Phase II Randomized, Placebo-Controlled Trial of PROSTVAC (PSA-TRICOM) in Patients with Clinically Localized Prostate Cancer Undergoing Active SurveillanceCompleted Study; data analyses ongoing18-99 YearsNCI Recurrent
15-C-0145Phase I/II Study of the Anti-Programmed Death Ligand-1 Antibody Durvalumab (MEDI4736) in Combination with Olaparib and/or Cediranib for Advanced Solid Tumors and Advanced or Recurrent Ovarian, Triple Negative Breast, Lung, Prostate and Colorectal CancersParticipants currently recruited/enrolled18-125 YearsNCI Recurrent
15-C-0029Phase I Dose Escalation Study of Anti-CD22 Chimeric Receptor T Cells in Pediatric and Young Adults with Recurrent or Refractory CD22-expressing B Cell MalignanciesParticipants currently recruited/enrolled3-39 YearsNCI Recurrent
15-AA-0203Cross-Sectional and Longitudinal Study of Structural ImagingCompleted Study; data analyses ongoing30-60 YearsNIAAAPregnancy
14-CC-0143Sleep Disturbance and Relapse in Individuals with Alcohol Dependence: An Exploratory Mixed Methods StudyCompleted Study; data analyses ongoing18-125 YearsCC Loss
14-C-0007Phase II Trial of the Gamma-Secretase Inhibitor Nirogacestat (PF-03084014) in Adults with Desmoid Tumors/Aggressive FibromatosisNo longer recruiting/follow-up only18-125 YearsNCI Loss
14-C-0001Phase II Study of Axitinib (AG-013736) with Evaluation of the VEGF-pathway in Metastatic, Recurrent or Primary Unresectable Pheochromocytoma/ParagangliomaCompleted Study; data analyses ongoing18-125 YearsNCI Recurrent
13-I-0157The Natural History of GATA2 Deficiency and Related DisordersParticipants currently recruited/enrolled2-100 YearsNIAIDLoss
13-H-0183Cardiovascular Health and Needs Assessment in Washington D.C. - Development of a Community-Based Behavioral Weight Loss InterventionParticipants currently recruited/enrolled19-85 YearsNHLBILoss
13-EI-0049Pathogenesis and Genetics of Microphthalmia, Anophthalmia and Uveal Coloboma ( MAC)Participants currently recruited/enrolled1-125 YearsNEI Pregnancy
13-DK-0212Effect of a Eucaloric Ketogenic Diet on Energy Expenditure: A Pilot StudyCompleted Study; data analyses ongoing18-50 YearsNIDDKLoss
13-CH-0001Intrathecal 2-Hydroxypropyl-B-Cyclodextrin in Patients with Niemann-Pick Disease, Type C1Completed Study; data analyses ongoing2-125 YearsNICHDLoss
13-C-0095A Phase 2 Study of GI-6207 in Patients with Recurrent Medullary Thyroid CancerCompleted Study; data analyses ongoing18-125 YearsNCI Recurrent
12-N-0031Imaging Biomarkers in Parkinson DiseaseCompleted Study; data analyses ongoing18-100 YearsNINDSLoss
12-EI-0203Natural History of ABCA4-Related RetinopathiesNo longer recruiting/follow-up only12-125 YearsNEI Loss
12-D-0100Oral Microbial and Immunological Characterization of Patients with Immune DysfunctionParticipants currently recruited/enrolled7-125 YearsNIDCRLoss
12-C-0081Phase I/II Study of Cediranib and Olaparib in Combination for Treatment of Recurrent Papillary-Serous Ovarian, Fallopian Tube, or Peritoneal Cancer or for Treatment of Recurrent Triple-Negative Breast CancerNo longer recruiting/follow-up only18-125 YearsNCI Recurrent
11-I-0183Screening for LID Clinical Studies Unit Healthy Volunteer ProtocolsParticipants currently recruited/enrolled18-65 YearsNIAIDPregnancy
11-EI-0264A Pilot Study for the Evaluation of Minocycline as a Microglia Inhibitor in the Treatment of Central Retinal Vein OcclusionsCompleted Study; data analyses ongoing18-125 YearsNEI Loss
11-EI-0263A Pilot Study for the Evaluation of Minocycline as a Microglia Inhibitor in the Treatment of Branch Retinal Vein OcclusionsCompleted Study; data analyses ongoing18-125 YearsNEI Loss
11-EI-0147Longitudinal Investigation of Dark Adaptation in Participants with Age-Related Macular DegenerationParticipants currently recruited/enrolled50-125 YearsNEI Loss
11-C-0220Natural History Study of the KSHV Inflammatory Cytokine Syndrome (KICS) Incorporating Pilot Evaluation of KSHV Targeted TherapiesParticipants currently recruited/enrolled18-125 YearsNCI Loss
11-C-0132Understanding the Psychosocial Needs of Parents Who Have Lost a Child to CancerCompleted Study; data analyses ongoing18-99 YearsNCI Loss
11-C-0033Extended Follow-up of High Ovarian Cancer Risk Cohort from 02C0268 (GOG-199)Completed Study; data analyses ongoing18-100 YearsNCI Pregnancy
10-N-0143A Prospective Natural History Study of Patients with SyringomyeliaNo longer recruiting/follow-up only18-125 YearsNINDSLoss
10-I-0216Studies of Disorders with Increased Susceptibility to Fungal InfectionsParticipants currently recruited/enrolled0-125 YearsNIAIDRecurrent
10-EI-0140Genotype - phenotype Study of Patients with Plaquenil-induced Retinal ToxicityParticipants currently recruited/enrolled18-125 YearsNEI Loss
10-C-0174Related and Unrelated Donor Hematopoietic Stem Cell Transplant for DOCK8 DeficiencyParticipants currently recruited/enrolled4-125 YearsNCI Recurrent
10-C-0054Administration of Anti-CD19-Chimeric-Antigen-Receptor-Transduced T Cells from the Original Transplant Donor to Patients with Recurrent or Persistent B-Cell Malignancies After Allogeneic Stem Cell TransplantationNo longer recruiting/follow-up only18-75 YearsNCI Recurrent
09-N-0039A Phase I Study of the Intrathecal Administration of Resiniferatoxin for Treating Severe Refractory Pain Associated with Advanced CancerParticipants currently recruited/enrolled18-125 YearsNINDSPregnancy
09-N-0010Biomarkers of Risk of Parkinson DiseaseCompleted Study; data analyses ongoing18-70 YearsNINDSLoss
09-I-0200A Phase I Study of MozobilTM in the Treatment of Patients with WHIMSParticipants currently recruited/enrolled18-75 YearsNIAIDLoss
09-I-0184Studies in the Pathogenesis of Systemic Capillary Leak SyndromeParticipants currently recruited/enrolled0-125 YearsNIAIDRecurrent
09-I-0102Etiology, Pathogenesis, and Natural History of Idiopathic CD4+ LymphocytopeniaParticipants currently recruited/enrolled18-125 YearsNIAIDPregnancy
09-I-0013Biomarkers of Inflammation, Coagulation, and Endothelial Function in HIV-Infected AdultsEnrolling by Invitation18-100 YearsNIAIDPregnancy
09-DK-0223Rituximab Plus Cyclosporine in Idiopathic Membranous NephropathyParticipants currently recruited/enrolled18-125 YearsNIDDKLoss
09-DK-0081Selective Reduction of Dietary Carbohydrate Versus Fat: Effects on Metabolism, Endocrine Physiology, Brain Activity and Reward CircuitryCompleted Study; data analyses ongoing18-45 YearsNIDDKLoss
09-C-0120An Exploratory Evaluation of Biomarkers in Blister Fluid in Healthy Volunteers and Irradiated SkinCompleted Study; data analyses ongoing18-125 YearsNCI Pregnancy
08-N-0044A Prospective Natural History Study of Patients with Neurofibromatosis Type 2 (NF2).Participants currently recruited/enrolled8-75 YearsNINDSLoss
08-DK-N191The Effects of Transcranial Direct Current Stimulation (TDCS) on Food Intake and Weight LossParticipants currently recruited/enrolled18-60 YearsNIDDKLoss
08-DK-0149High Dose Ribavirin in Combination with Peginterferon for Patients with Chronic Hepatitis C Genotype 1 Infection Who Have Failed to Respond or Relapsed after Standard TherapyCompleted Study; data analyses ongoing18-65 YearsNIDDKPregnancy
08-AA-0178Computer-Assisted Self-Administration of Ethanol (CASE) in HumansParticipants currently recruited/enrolled21-60 YearsNIAAAPregnancy
07-I-0033Screening Protocol for Detection and Characterization of Infections and Infection SusceptibilityParticipants currently recruited/enrolled0-125 YearsNIAIDRecurrent
07-E-0012Rituximab in the Treatment of Refractory Adult and Juvenile Dermatomyositis (DM) and Adult Polymyositis (PM)Completed Study; data analyses ongoing2-125 YearsNIEHSPregnancy
07-DK-N215Study of Short-Term Metabolic Adaptation: Prediction of Weight Change and Effects of Macronutrient ManipulationsCompleted Study; data analyses ongoing18-55 YearsNIDDKPregnancy
07-CH-0008Prospective, Open-Label, Multicenter, International Study of Mifepristone for Symptomatic Treatment of Cushing's Syndrome Caused by Ectopic Adrenal Corticotrophin Hormone (ACTH) SecretionCompleted Study; data analyses ongoing18-85 YearsNICHDPregnancy
06-H-0217Genetic Disorders of Mucociliary ClearanceCompleted Study; data analyses ongoing2-65 YearsNHLBIPregnancy
06-H-0190Treatment of T-Large Granular Lymphocyte (T-LGL) Lymphoproliferative Disorders with Alemtuzumab (Campath)Completed Study; data analyses ongoing18-85 YearsNHLBIRecurrent
06-CH-0186Evaluation of Biochemical Markers and Clinical Investigation of Niemann-Pick Disease, Type CParticipants currently recruited/enrolled0-125 YearsNICHDLoss
06-C-0219An Exploratory Study of Biologic and Pathophysiologic Effects of Radiation Therapy in Pediatric Patients with Central Nervous System TumorsCompleted Study; data analyses ongoing0-21 YearsNCI Pregnancy
05-I-0213Screening and Baseline Assessment of Patients with Abnormalities of Immune FunctionParticipants currently recruited/enrolled0-125 YearsNIAIDRecurrent
05-CH-0037The Effects of Hydrocortisone, Melatonin, and Placebo on Symptoms of Jet LagCompleted Study; data analyses ongoing18-65 YearsNICHDPregnancy
04-DK-0021Urinary Vitamin C Loss in Subjects with and without DiabetesParticipants currently recruited/enrolled18-65 YearsNIDDKLoss
04-CC-0046Citrate Effects and Bone Density Studies in Long-Term Apheresis DonorsCompleted Study; data analyses ongoing18-80 YearsCC Loss
04-AR-0205Progression of Spinal Fusion in Ankylosing SpondylitisCompleted Study; data analyses ongoing18-125 YearsNIAMSPregnancy
03-EI-0033X-Linked Juvenile Retinoschisis - Clinical and Molecular StudiesParticipants currently recruited/enrolled0-125 YearsNEI Loss
03-E-0099Pathogenic Studies In Families With Twins Or Siblings Discordant For Systemic Rheumatic DisordersCompleted Study; data analyses ongoing2-125 YearsNIEHSPregnancy
03-DA-N380Advanced Functional and Structural MRI Techniques for Neuropharmacological ImagingParticipants currently recruited/enrolled18-80 YearsNIDA Pregnancy
03-C-0278A Comparative Study of Pediatric CNS Tumor Activity as Assessed by 18F-FDG PET Imaging and Proton Magnetic Resonance Spectroscopic Imaging (1H-MRSI)Completed Study; data analyses ongoing1-21 YearsNCI Pregnancy
03-C-0066Hereditary Leiomyomatosis Renal Cell Cancer (HLRCC): Identification of the Disease Gene, and Characterization of the Predisposition to Renal CancerParticipants currently recruited/enrolled2-125 YearsNCI Pregnancy
02-I-0202Leukapheresis Procedures to Obtain Plasma and Lymphocytes for Research Studies on Antiretroviral-Naive HIV-Infected PatientsParticipants currently recruited/enrolled18-125 YearsNIAIDLoss
02-DK-N304Diabetes Prevention Program Outcomes Study (DPPOS)No longer recruiting/follow-up only25-125 YearsNIDDKLoss
02-DK-0022Long-Term Efficacy of Leptin Replacement in Treatment of LipodystrophyCompleted Study; data analyses ongoing1-125 YearsNIDDKLoss
01-I-0202Natural History, Genetics, Phenotype, and Treatment of Mycobacterial InfectionsParticipants currently recruited/enrolled0-100 YearsNIAIDRecurrent
01-DC-0229Genetic Analysis of Hereditary Disorders of Hearing and BalanceCompleted Study; data analyses ongoing0-99 YearsNIDCDLoss
01-DC-0228Clinical and Molecular Analysis of Enlarged Vestibular AqueductsCompleted Study; data analyses ongoing0-99 YearsNIDCDLoss
00-N-0140A Prospective Natural History Study of VHL Patients with CNS HemangioblastomasNo longer recruiting/follow-up only8-75 YearsNINDSPregnancy
00-I-0159Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection Syndrome (HIES)Participants currently recruited/enrolled0-125 YearsNIAIDRecurrent
00-HG-0153Investigations into Chediak-Higashi Syndrome and Related DisordersParticipants currently recruited/enrolled0-70 YearsNHGRIRecurrent
00-H-0051Cutaneous Tumorigenesis in Patients with Tuberous SclerosisParticipants currently recruited/enrolled18-90 YearsNHLBILoss
00-CH-0136A Trial of Pamidronate in Children with Osteogenesis ImperfectaCompleted Study; data analyses ongoing2-17 YearsNICHDLoss
97-CH-0064Evaluation and Intervention for Ambulation, Growth, and Basilar Invagination in Osteogenesis ImperfectaCompleted Study; data analyses ongoing0-10 YearsNICHDLoss
95-M-0097An Endocrine Model for Postpartum Mood DisordersParticipants currently recruited/enrolled18-50 YearsNIMH Pregnancy
94-E-0165Studies in the Natural History and Pathogenesis of Childhood-Onset and Adult-Onset Idiopathic Inflammatory MyopathiesParticipants currently recruited/enrolled2-100 YearsNIEHSLoss
94-DK-0133Genetic Markers for Focal Segmental GlomerulosclerosisCompleted Study; data analyses ongoing1-125 YearsNIDDKLoss
94-C-0074Treatment and Natural History Study of Lymphomatoid GranulomatosisParticipants currently recruited/enrolled12-125 YearsNCI Loss
93-I-0119Detection and Characterization of Host Defense DefectsParticipants currently recruited/enrolled0-125 YearsNIAIDRecurrent
92-M-0174The Central Nervous System Effects of Pharmacologically Induced Hypogonadotropic Hypogonadism with and without Estrogen and Progesterone ReplacementCompleted Study; data analyses ongoing18-50 YearsNIMH Pregnancy
91-I-0140Studies of the Pathogenesis of HIV Infection in Human Peripheral Blood Cells and/or Body Fluids in HIV-Infected and HIV-Uninfected VolunteersParticipants currently recruited/enrolled18-125 YearsNIAIDPregnancy
90-M-0088The Treatment of Menstrually-Related Mood Disorders with the Gonadotropin Releasing Hormone (GnRH) Agonist, Depot Leuprolide Acetate (Lupron)Completed Study; data analyses ongoing18-45 YearsNIMH Pregnancy
81-M-0126The Evaluation of Women with Menstrually Regulated Mood and Behavioral DisordersParticipants currently recruited/enrolled18-50 YearsNIMH Recurrent
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