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Protocol Number Title Protocol Status Min-Max Age Institute Keywords
000236-IA Phase 1 Study of Empagliflozin as Treatment for Severe Congenital Neutropenia Due to G6PC3 DeficiencyParticipants currently recruited/enrolled18-125 YearsNIAIDNeutropenia Congenital
09-H-0225Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Severe Congenital Anemias Including Sickle Cell Disease and Beta-ThalassemiaNo longer recruiting/follow-up only2-125 YearsNHLBICongenital 9
09-H-0199A Pilot Study of a Thrombopoietin-Receptor Agonist (TPO-R agonist), Eltrombopag, in Patients with Low to Int-2 Risk Myelodysplastic Syndrome (MDS)Completed Study; data analyses ongoing18-125 YearsNHLBINeutropenia 9
02-C-0052Etiologic Investigation of Cancer Susceptibility in Inherited Bone Marrow Failure Syndromes: A Natural History StudyParticipants currently recruited/enrolled0-125 YearsNCI Neutropenia Congenital
97-H-0041Screening Protocol for Subjects Being Evaluated for National Heart, Lung and Blood Institute (NHLBI) ProtocolsEnrolling by Invitation2-125 YearsNHLBINeutropenia 9
96-CH-0033An Open, Randomized, Long-Term Clinical Trial of Flutamide, Testolactone, and Reduced Hydrocortisone Dose vs. Conventional Treatment of Children with Congenital Adrenal HyperplasiaNo longer recruiting/follow-up only2-18 YearsNICHDCongenital 9
94-HG-0132The Phenotype and Etiology of Proteus SyndromeParticipants currently recruited/enrolled0-125 YearsNHGRICongenital 9
001085-DPhase 2 Study of the PTH-Independent Effects of Encaleret on Mineral Homeostasis in Subjects with Post-Surgical Hypoparathyroidism (PSH)Recruitment has not started18-125 YearsNIDCR9
001078-IPhase 1 Trial to Model Primary, Secondary, and Tertiary Dengue Using a Monovalent VaccineParticipants currently recruited/enrolled18-59 YearsNIAID9
001061-HObservational Study Investigating the Mechanistic Effects of Mitapivat in Subjects with Sickle Cell DiseaseEnrolling by Invitation16-125 YearsNHLBI9
001056-CLongitudinal Early Advance Care Planning Discussions and Documentation (LEADD) Program: An Exploratory Study in Adolescents and Young Adults (AYAs) Receiving Hematopoietic Stem Cell TransplantParticipants currently recruited/enrolled18-125 YearsNCI 9
000809-IA Pilot Study of Fecal Microbiota Transplantation for Chronic Granulomatous Disease-Associated ColitisParticipants currently recruited/enrolled10-60 YearsNIAID9
000783-CPhase I/Ib Trial Evaluating the Safety and Efficacy of BET Inhibitor, ZEN003694 with PD-1 Inhibitor, Nivolumab with or without CTLA-4 Inhibitor, Ipilumumab in Solid TumorsParticipants currently recruited/enrolled18-125 YearsNCI 9
000782-CA Dose-Escalation and Expansion Study of the Safety and Pharmacokinetics of XL092 as Single-Agent and Combination Therapy in Subjects with Inoperable Locally Advanced or Metastatic Solid TumorsRecruitment has not started18-125 YearsNCI 9
000780-DA Phase 2 Study of Denosumab for Prevention of Skeletal Disease Progression in Children with Fibrous DysplasiaParticipants currently recruited/enrolled4-14 YearsNIDCR9
000740-CHA Phase 3 Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of Chronocort in the Treatment of Participants Aged 16 Years and Over with Congenital Adrenal HyperplasiaEnrolling by Invitation18-125 YearsNICHDCongenital
000682-ARThe Role of Anifrolumab in Improving Markers of Vascular Risk in Patients with Systemic Lupus ErythematosusRecruitment has not started18-80 YearsNIAMS9
000647-CAn Open-label, Multicenter Follow-up Study to Collect Long-term Data on Participants from Multiple Bintrafusp alfa (M7824) Clinical StudiesRecruitment has not started18-125 YearsNCI 9
000633-CPhase 1/2 Study of VIP152, Venetoclax, and Prednisone (VVIP) in Relapsed/Refractory Lymphoid MalignanciesParticipants currently recruited/enrolled18-125 YearsNCI 9
000612-CPhase 1 Study of NT-I7 (rhIL-7-hyFc) for the Treatment of Kaposi Sarcoma in Patients With or Without Infection with HIVParticipants currently recruited/enrolled18-125 YearsNCI 9
000567-CPhase 1 Trial of Gemcitabine Combined with the BAY 1895344 ATR Inhibitor with Expansion Cohorts in Advanced Pancreatic and Ovarian CancerParticipants currently recruited/enrolled18-125 YearsNCI 9
000494-DKNatural History of Fontan Associated Liver Disease and the Evaluation of Biomarkers for Disease Severity AssessmentParticipants currently recruited/enrolled18-125 YearsNIDDKCongenital
000483-MPET Imaging of Cyclooxygenases in Multiple SclerosisParticipants currently recruited/enrolled18-99 YearsNIMH 9
000476-EThe Investigation of Vitamin D and Menstrual Cycles Trial: A Phase II Clinical trialParticipants currently recruited/enrolled19-40 YearsNIEHS9
000413-HNatural History study of CADASILParticipants currently recruited/enrolled18-100 YearsNHLBI9
000411-CCA Feasibility Pilot Study of a Virtual Education-Based Transition Intervention to Improve Transition Readiness in Adolescent and Young Adults with Congenital Adrenal Hyperplasia.Recruitment has not started16-22 YearsCC Congenital
000406-AAAddictions Neuroclinical AssessmentEnrolling by Invitation18-125 YearsNIAAA9
000324-CPhase 1/2 Dose Escalation Study of CD19/CD22 Bicistronic Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults with Recurrent or Refractory CD19/CD22-expressing B Cell MalignanciesParticipants currently recruited/enrolled3-35 YearsNCI 9
000320-IRandomized, Double-Blinded, Placebo-Controlled, Phase 1 Study of the Safety and Immunogenicity of BPL-1357, A BPL-Inactivated, Whole-Virus, Universal Influenza VaccineParticipants currently recruited/enrolled18-55 YearsNIAID9
000310-CHA Phase 1/2, First-in-Human, Open-Label, Dose-Escalation Study of the Safety and Efficacy of Gene Therapy for Congenital Adrenal Hyperplasia through Administration of an Adeno-Associated Virus (AAV) Serotype 5-Based Recombinant Vector Encoding the Human Recruitment has not started18-125 YearsNICHDCongenital
000297-CHA Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Crinecerfont (NBI-74788) in Adult Subjects with Classic Congenital Adrenal Hyperplasia, Followed by Open-Label TreatmentParticipants currently recruited/enrolled18-125 YearsNICHDCongenital
000291-IObservational Digital Biomarker Discovery in Respiratory Virus Challenge StudiesRecruitment has not started18-65 YearsNIAID9
000277-CImaging and Biopsy of HIV-Infected Individuals Undergoing Analytic Treatment InterruptionParticipants currently recruited/enrolled18-125 YearsNCI 9
000274-CPhase I Trial of Pomalidomide and Dose-Adjusted EPOCH +/- Rituximab for HIV-Associated LymphomasParticipants currently recruited/enrolled18-125 YearsNCI 9
000241-CHPhase II Trial of Liraglutide (Saxenda(R), Novo Nordisk) in Adolescents with Obesity After Sleeve Gastrectomy: A Pilot Open-Label StudyParticipants currently recruited/enrolled12-20 YearsNICHD9
000212-IInduced Blood-Stage Plasmodium Vivax Infection with HMPBS02-Pv Challenge Agent in Healthy Malaria-Naive Adults to Produce a Plasmodium Vivax Parasite Cell Bank for Future StudiesNo longer recruiting/follow-up only18-50 YearsNIAID9
000206-CHEndometrial Basis for Infertility in Women with Recurrent Implantation Failure and Pregnancy LossParticipants currently recruited/enrolled18-42 YearsNICHD9
000186-IPart B- Phase I/II, Non-randomized, Multicenter, Open-label Study of G1XCGD (Lentiviral Vector Transduced CD34+ Cells) in Patients with X-Linked Chronic Granulomatous DiseaseClinical hold/Recruitment or enrollment suspended3-12 YearsNIAID9
000144-CA Phase I/II Study of Sacituzumab Govitecan plus Berzosertib in Small Cell Lung Cancer, Extra-Pulmonary Small Cell Neuroendocrine Cancer and Homologous Recombination-Deficient Cancers Resistant to PARP InhibitorsParticipants currently recruited/enrolled18-125 YearsNCI 9
000137-CHImplications of Maternal 45,X Mosaicism As A Secondary Genomic Finding Following Cell-free DNA Sequencing During Pregnancy: A Deep Phenotype StudyRecruitment has not started18-99 YearsNICHD9
000118-DKProspective Cohort Study to Determine the Response to COVID-19 Vaccination and Prevalence of COVID-19 in Subjects with Chronic Liver DiseaseParticipants currently recruited/enrolled18-100 YearsNIDDK9
000079-DKThe Role of 68-Gallium-DOTATATE-PET/CT in the Imaging of Metastatic Thyroid CancerParticipants currently recruited/enrolled18-125 YearsNIDDK9
000064-IA Phase 1/2 Open-label Study to Evaluate the Safety and Efficacy of Tofacitinib for Chronic Granulomatous Disease with Inflammatory ComplicationsEnrolling by Invitation18-125 YearsNIAID9
000062-CPhase I Evaluation of Immunotoxin LMB-100 Administered by Normothermic, Intrapleural Perfusion Following Cytoreductive Surgery in Participants with Pleural Mesotheliomas, or Pleural Effusions from Cancers Expressing MesothelinParticipants currently recruited/enrolled18-120 YearsNCI 9
000036-AAA Phase I, Randomized, Double-Blind, Placebo-Controlled, Study of Safety, Tolerability, and Bioeffects of Alirocumab in Non-treatment Seeking Heavy DrinkersParticipants currently recruited/enrolled21-65 YearsNIAAA9
22-C-0005Phase I Dose Escalation and Expansion Study of Tazemetostat in Combination with Topotecan and Pembrolizumab in Recurrent Small Cell Lung CancerParticipants currently recruited/enrolled18-125 YearsNCI 9
21-N-0016Phase I/II Study of Teriflunomide in HTLV-1 Associated Myelopathy/Tropical Spastic ParaparesisParticipants currently recruited/enrolled18-125 YearsNINDS9
21-N-0010A Phase 2 Clinical Trial of Tolebrutinib, a Brain-penetrant Bruton's Tyrosine Kinase Inhibitor, for the Modulation of Chronically Inflamed White Matter Lesions in Multiple SclerosisNo longer recruiting/follow-up only18-125 YearsNINDS9
21-C-0023A Phase I Study of Pomalidomide and Nivolumab in Patients with Virus-Associated Malignancies With or Without HIVParticipants currently recruited/enrolled18-125 YearsNCI 9
20-M-0157PET Imaging of Cyclooxygenase in Participants with Major Depressive Disorder (MDD)Participants currently recruited/enrolled18-70 YearsNIMH 9
20-I-0096VRC 611: A Phase 1 Safety and Pharmacokinetic Study to Evaluate a Human Monoclonal Antibody (mAb) VRC-HIVMAB0102-00-AB (CAP256V2LS) Administered via Subcutaneous and Intravenous Injection in Healthy AdultsNo longer recruiting/follow-up only18-60 YearsNIAID9
20-I-0002Pilot Study of Mepolizumab in Episodic Angioedema with EosinophiliaCompleted Study; data analyses ongoing18-125 YearsNIAID9
20-H-0137A Study to Evaluate the Effects of Fixed Dose Flavonoid Isoquercetin on Thrombo-Inflammatory Biomarkers in Subjects with Stable Sickle Cell DiseaseCompleted Study; data analyses ongoing18-46 YearsNHLBI9
20-D-0131Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sj(SqrRoot)(Delta)gren's Syndrome; a Phase Ib-IIa Placebo-controlled Clinical Trial and Associated Mechanistic StudiesParticipants currently recruited/enrolled18-75 YearsNIDCR9
20-D-0094Transmissibility and Viral Load of SARS-CoV-2 Through Oral SecretionsCompleted Study; data analyses ongoing18-125 YearsNIDCR9
20-CH-0126Data Collection Study of Pediatric and Adolescent Gynecology ConditionsParticipants currently recruited/enrolled0-125 YearsNICHDCongenital
20-C-0127A Phase 1 Study of Romidepsin, CC-486 (5-azacitidine), dexamethasone, and lenalidomide (RAdR) for relapsed/refractory T-cell malignanciesParticipants currently recruited/enrolled18-125 YearsNCI 9
20-C-0070A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Patients with Inborn Errors of ImmunityParticipants currently recruited/enrolled4-69 YearsNCI Congenital
20-C-0069A First-In-Human Phase I Single-Agent Dose-Escalation, Food Effect and Dose Expansion Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System NeoplasmsParticipants currently recruited/enrolled18-125 YearsNCI 9
20-C-0061Phase I/II study of NHS-IL12 Monotherapy and in Combination with M7824 in Advanced Kaposi SarcomaParticipants currently recruited/enrolled18-125 YearsNCI 9
20-C-0028Phase 1/2 Study of Anti-CD33 Chimeric Antigen Receptor-Expressing T Cells (CD33CART) in Children and Young Adults with Relapsed/Refractory Acute Myeloid LeukemiaParticipants currently recruited/enrolled3-35 YearsNCI 9
20-C-0023First-in-Human Phase I Trial to Investigate the Safety, Tolerability, Pharmacokinetics, Biological and Clinical Activity of Metarrestin (ML-246) in Subjects with Metastatic Solid TumorsParticipants currently recruited/enrolled12-125 YearsNCI 9
20-C-0011Phase 1 Study of Recombinant Human IL-15 (rhIL-15) and Mogamulizumab for Patients with Refractory or Relapsed Adult T-Cell Leukemia and Mycosis Fungoides/Sezary SyndromeCompleted Study; data analyses ongoing18-125 YearsNCI 9
19-M-0107The Mechanism of Action Underlying Ketamine's Antidepressant Effects: An Investigation of the AMPA Throughput Theory in Patients with Treatment-Resistant Major DepressionParticipants currently recruited/enrolled18-70 YearsNIMH 9
19-I-0126Systems Analyses of the Immune Response to the Seasonal Influenza VaccineCompleted Study; data analyses ongoing18-125 YearsNIAID9
19-I-0069Phase I Open-Label Study of Safety and Immunogenicity of AD4-HIV Envelope Vaccine Vectors in Healthy VolunteersParticipants currently recruited/enrolled18-65 YearsNIAID9
19-I-0058Mucosal Correlates of Protection After Influenza Viral Challenge of Vaccinated and Unvaccinated Healthy VolunteersCompleted Study; data analyses ongoing18-55 YearsNIAID9
19-CH-0026Randomized, Double-Blind, Placebo-Controlled Study Plus Open Label Extension with a Double-Blind, Placebo-Controlled, Randomized Withdrawal Period of Diazoxide Choline Extended-Release Tablets (DCCR, Soleno Therapeutics, Inc.) in Participants with PraderNo longer recruiting/follow-up only4-125 YearsNICHD9
19-CH-0020A Phase 1-2 Multi-Center Study to Assess the Efficacy and Safety of Abiraterone Acetate as Adjunctive Therapy in Pre-Pubescent Children with Classic 21-Hydroxylase DeficiencyRecruitment has not started2-9 YearsNICHDCongenital
19-CC-0063Impact of Steady State Cobicistat and Darunavir/Cobicistat on the Pharmacokinetics and Pharmacodynamics of Oral Anticoagulants (Rivaroxaban, Apixaban) in Healthy VolunteersParticipants currently recruited/enrolled18-65 YearsCC 9
19-C-0137A Phase II Study of Ipilimumab, Cabozantinib, and NIvolumab in Rare Genitourinary Cancers (ICONIC)Participants currently recruited/enrolled18-125 YearsNCI 9
19-C-0127A Phase II Study of LMB-100 Followed by Pembrolizumab in the Treatment of Adults with Mesothelin-Expressing Non-Squamous Non-Small Cell Lung Cancer (NSCLC)No longer recruiting/follow-up only18-125 YearsNCI 9
19-C-0102A Phase I Clinical Trial of T-cells Expressing an anti-SLAMF7 CAR for Treating Multiple MyelomaCompleted Study; data analyses ongoing18-73 YearsNCI 9
19-C-0094A Phase II Study of Combined Treatment of Durvalumab, Bevacizumab, Tremelimumab and Transarterial Chemoembolization (TACE) in Subjects with Hepatocellular Carcinoma (HCC) or Biliary Tract Carcinoma (BTC)Participants currently recruited/enrolled18-125 YearsNCI 9
19-C-0085Phase II Trial of Allogeneic Hematopoietic Cell Transplantation for Peripheral T cell LymphomaClinical hold/Recruitment or enrollment suspended12-125 YearsNCI Congenital
19-C-0076A Phase 1 Study of Interleukin-15 in Combination with Avelumab (Bavencio) in Relapsed/Refractory Mature T-cell MalignanciesCompleted Study; data analyses ongoing18-125 YearsNCI 9
19-C-0017A Phase I/II Study Administering Peripheral Blood Lymphocytes Transduced with a Murine T-Cell Receptor Recognizing the G12D Variant of Mutated RAS in HLA-A*11:01 PatientsParticipants currently recruited/enrolled18-70 YearsNCI 9
19-C-0016Natural History and Biospecimen Acquisition Study for Children and Adults with Rare Solid TumorsParticipants currently recruited/enrolled0-125 YearsNCI 9
18-M-0144The effects of an ER beta agonist (Lilly Compound LY500307) on estradiol-withdrawal-induced mood symptoms in women with past perimenopausal depression.Participants currently recruited/enrolled45-65 YearsNIMH 9
18-I-0128Send-In Sample Collection to Achieve Genetic and Immunologic Characterization of Primary ImmunodeficienciesParticipants currently recruited/enrolled0-99 YearsNIAID9
18-I-0092A Phase 2, Open-Label Study to Assess the Immunogenicity of the 9-Valent Human Papillomavirus Recombinant Vaccine in Patients with Idiopathic CD4 T cell LymphocytopeniaParticipants currently recruited/enrolled18-70 YearsNIAID9
18-D-0114An Open Label Pilot Study of Denosumab Treatment for Fibrous DysplasiaNo longer recruiting/follow-up only18-125 YearsNIDCR9
18-CH-0001Mirror Neuron Network Dysfunction as an Early Biomarker of Neurodevelopmental DisorderParticipants currently recruited/enrolled0-65 YearsNICHD9
18-CC-0013A Randomized, Double-Blind, Placebo-Controlled Study of a Single Dose of Pembrolizumab in HIV-Infected PatientsParticipants currently recruited/enrolled18-99 YearsCC 9
18-C-0143A Phase 1 Study of Intraperitoneal MCY-M11 Therapy for Women with Platinum Resistant High Grade Serous Adenocarcinoma of the Ovary, Primary Peritoneum, or Fallopian Tube, or Subjects with Peritoneal Mesothelioma with Recurrence after Prior ChemotherapyCompleted Study; data analyses ongoing18-125 YearsNCI 9
18-C-0135Phase II Trial of Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or DysregulationParticipants currently recruited/enrolled4-125 YearsNCI Congenital
18-C-0125A Phase I Clinical Trial of T cells Expressing a Novel Fully-human Anti-BCMA CAR for Treating Multiple MyelomaNo longer recruiting/follow-up only18-73 YearsNCI 9
18-C-0122Phase 1B Study of Copanlisib in Combination with Nivolumab or with Nivolumab and IpilimumabCompleted Study; data analyses ongoing18-125 YearsNCI 9
18-C-0080Feasibility and Preliminary Efficacy of an Enhanced Mindfulness Intervention for Children and Young Adults with High Grade or High-Risk Cancer and Their Caregivers: A Pilot Randomized Controlled TrialCompleted Study; data analyses ongoing5-125 YearsNCI 9
17-H-0095Heart Catheterization Using Magnetic Resonance Imaging (MRI) Fluoroscopy and Passive GuidewiresParticipants currently recruited/enrolled18-125 YearsNHLBICongenital
17-DK-0013Therapeutic Targets in African-American Youth with Type 2 DiabetesParticipants currently recruited/enrolled12-25 YearsNIDDK9
17-C-0048Anti-CD30 CAR T Cells with Fully-human Binding Domains for Treating CD30-expressing Lymphomas Including Anaplastic Large Cell LymphomasCompleted Study; data analyses ongoing18-73 YearsNCI 9
17-C-0007Phase I/II Study of PROSTVAC in Combination with Nivolumab in Men with Prostate CancerParticipants currently recruited/enrolled18-125 YearsNCI 9
17-AA-0171Nicotinic Receptor Genetic Variation and Alcohol RewardParticipants currently recruited/enrolled21-60 YearsNIAAA9
16-N-0072A Pilot Study of Adoptive Cellular Immunotherapy for Progressive Multifocal Leukoencephalopathy with Ex Vivo Generated Polyomavirus-Specific T-cellsCompleted Study; data analyses ongoing18-125 YearsNINDS9
16-N-0058Myalgic Encephalomyelitis/Chronic Fatigue SyndromeCompleted Study; data analyses ongoing18-60 YearsNINDS9
16-N-0055The Pathological Basis of MRI Signal Changes in Multiple Sclerosis: A Longitudinal In Vivo-to-Postmortem StudyParticipants currently recruited/enrolled18-125 YearsNINDS9
16-EI-0169A Pilot Study to Investigate Ustekinumab (STELARA) for the Treatment of Active Sight-Threatening UveitisCompleted Study; data analyses ongoing18-125 YearsNEI 9
16-E-0157CaREFREE Study (Calorie Restriction, Environment and Fitness: Reproductive Effects Evaluation Study)Completed Study; data analyses ongoing18-28 YearsNIEHS9
16-CH-0164A Phase III Extension Study of Efficacy, Safety and Tolerability of Chronocort (Registered) in the Treatment of Congenital Adrenal HyperplasiaCompleted Study; data analyses ongoing18-80 YearsNICHDCongenital
16-CC-0112Impact of Once-Weekly Rifapentine and Isoniazid on the Steady State Pharmacokinetics of Dolutegravir and Darunavir Boosted with Cobicistat in Healthy VolunteersCompleted Study; data analyses ongoing18-65 YearsCC 9
16-CC-0056Analysis of A Tool to Assess Psycho Social Spiritual Healing: Cognitive InterviewingCompleted Study; data analyses ongoing18-125 YearsCC 9
16-C-0054T Cells Expressing a Fully-human Anti- CD19 Chimeric Antigen Receptor for Treating B-cell MalignanciesNo longer recruiting/follow-up only18-73 YearsNCI 9
16-C-0003Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary ImmunodeficienciesParticipants currently recruited/enrolled4-75 YearsNCI Congenital
15-DK-0108Natural History of Noncirrhotic Portal HypertensionParticipants currently recruited/enrolled12-125 YearsNIDDKCongenital
15-DK-0100A Multidisciplinary Approach to Deciphering the Mechanisms Involved In Microbial Translocation Across the Spectrum of HCV Associated Liver FibrosisCompleted Study; data analyses ongoing18-125 YearsNIDDK9
15-C-0195Development and Validation of Patient Reported Outcome (PRO) Measures for Individuals with Neurofibromatosis 1 (NF1) and Plexiform Neurofibromas (pNFs)Participants currently recruited/enrolled5-125 YearsNCI 9
15-C-0099A Phase 1, Open-Label, Dose-Escalation Study of SNX-5422 and Everolimus in Subjects with Neuroendocrine TumorsCompleted Study; data analyses ongoing18-100 YearsNCI 9
15-C-0076A Pilot Study of Long Term TARP Vaccination Using A Multi-Epitope TARP Peptide Autologous Dendritic Cell Vaccination in Previously Vaccinated Men on NCI 09-C-0139Completed Study; data analyses ongoing18-125 YearsNCI 9
15-C-0075A Randomized, Placebo-Controlled Phase II Study of Multi-Epitope TARP Peptide Autologous Dendritic Cell Vaccination in Men with Stage D0 Prostate CancerCompleted Study; data analyses ongoing18-125 YearsNCI 9
15-AG-0123Intermittent Calorie Restriction, Insulin Resistance, and Biomarkers of Brain FunctionCompleted Study; data analyses ongoing55-70 YearsNIA 9
14-I-0185A Phase III Double-Blind Randomized Crossover Study of Plerixafor Versus G-CSF in the Treatment of Patients with WHIM Syndrome.Completed Study; data analyses ongoing10-75 YearsNIAIDNeutropenia
14-I-0063An Open-Label, Proof-of-Concept Study to Evaluate the Safety and Efficacy of Dexpramipexole (KNS-760704) in Subjects with Hypereosinophilic SyndromeNo longer recruiting/follow-up only18-125 YearsNIAID9
14-I-0039Elite Controller and ART-Treated HIV+ Statin Versus ASA Treatment Intervention StudyCompleted Study; data analyses ongoing18-125 YearsNIAID9
14-HG-0071Clinical and Basic Investigations into Known and Suspected Congenital Disorders of GlycosylationParticipants currently recruited/enrolled1-80 YearsNHGRICongenital
14-HG-0055Study on Moebius Syndrome and Other Congenital Facial Weakness DisordersCompleted Study; data analyses ongoing2-80 YearsNHGRICongenital
14-EI-0064Whole Exome and Whole Genome Sequencing for Genotyping of Inherited and Congenital Eye ConditionsParticipants currently recruited/enrolled1-125 YearsNEI Congenital
14-DK-0060Famine from Feast: Linking Vitamin C, Red Blood Cell Fragility, and DiabetesParticipants currently recruited/enrolled18-65 YearsNIDDK9
14-AA-0080Characterization Imaging Instruments for Addiction Neuroimaging AssessmentsParticipants currently recruited/enrolled18-125 YearsNIAAA9
13-N-0135Pilot Study of Raltegravir, an Integrase Inhibitor, in Human T-Cell Lymphotrophic Virus-1(HTLV-1) Associated Myelopathy, Tropical Spastic Paraparesis (HAM/TSP)Completed Study; data analyses ongoing18-125 YearsNINDS9
13-H-0133Extended Dosing with Eltrombopag in Refractory Severe Aplastic AnemiaCompleted Study; data analyses ongoing2-125 YearsNHLBINeutropenia
12-N-0031Imaging Biomarkers in Parkinson DiseaseCompleted Study; data analyses ongoing18-100 YearsNINDS9
12-H-0141Prospective Evaluation of New Techniques in Radiation Reduction for Cardiovascular Computed Tomographic AngiographyParticipants currently recruited/enrolled18-125 YearsNHLBI9
12-EI-0203Natural History of ABCA4-Related RetinopathiesNo longer recruiting/follow-up only12-125 YearsNEI 9
12-E-0061The Role of the Functionally Relevant Single Nucleotide Polymorphisms CYP2J2 -50G>T (CYP2J2 7) and EPHX2 9846A>G (EPHX2 K55R) in Human Endothelial FunctionCompleted Study; data analyses ongoing18-65 YearsNIEHS9
12-CC-0139Estimation of Brain Biomechanics using MRIParticipants currently recruited/enrolled18-65 YearsCC 9
11-NR-0014Characterizing Fatigue Experienced by Cancer Patients Receiving Primary Treatment and Cancer SurvivorsParticipants currently recruited/enrolled18-125 YearsNINR 9
11-I-0007Lentiviral Gene Transfer for Treatment of Children Older Than 2 Years of Age with X-Linked Severe Combined ImmunodeficiencyClinical hold/Recruitment or enrollment suspended2-40 YearsNIAID9
11-H-0134A Pilot Study of a Thrombopoietin-Receptor Agonist (TPO-R Agonist), Eltrombopag, in Moderate Aplastic Anemia PatientsNo longer recruiting/follow-up only2-125 YearsNHLBINeutropenia
11-EI-0147Longitudinal Investigation of Dark Adaptation in Participants with Age-Related Macular DegenerationParticipants currently recruited/enrolled50-125 YearsNEI 9
11-C-0136Multi-Institutional Prospective Pilot Study of Lupron to Enhance Lymphocyte Immune Reconstitution Following Allogeneic Bone Marrow Transplantation in Post-Pubertal Children and Adults with Molecular Imaging EvaluationCompleted Study; data analyses ongoing2-55 YearsNCI 9
11-C-0132Understanding the Psychosocial Needs of Parents Who Have Lost a Child to CancerCompleted Study; data analyses ongoing18-99 YearsNCI 9
10-N-0122Evaluation, Pathogenesis, and Outcome of Subjects with or Suspected Traumatic Brain InjuryCompleted Study; data analyses ongoing18-125 YearsNINDS9
10-I-0109VRC 900: Evaluation of Tissue-Specific Immune Responses in Adults 18 Years of Age and OlderParticipants currently recruited/enrolled18-125 YearsNIAID9
10-HG-0076Mothers' Thoughts about what their Children EatCompleted Study; data analyses ongoing18-100 YearsNHGRI9
10-HG-0065Whole Genome Medical Sequencing for Gene DiscoveryParticipants currently recruited/enrolled0-125 YearsNHGRICongenital
10-CC-0149Comparing Expectorated and Induced Sputum and Pharyngeal Swabs for Cultures, AFB Smears, and Cytokines in Pulmonary Nontuberculous Mycobacterial InfectionCompleted Study; data analyses ongoing18-80 YearsCC 9
10-CC-0115Imaging Techniques in MRIParticipants currently recruited/enrolled18-125 YearsCC 9
10-C-0174Related and Unrelated Donor Hematopoietic Stem Cell Transplant for DOCK8 DeficiencyParticipants currently recruited/enrolled4-125 YearsNCI 9
10-C-0054Administration of Anti-CD19-Chimeric-Antigen-Receptor-Transduced T Cells from the Original Transplant Donor to Patients with Recurrent or Persistent B-Cell Malignancies After Allogeneic Stem Cell TransplantationNo longer recruiting/follow-up only18-75 YearsNCI 9
10-C-0011Phase II Trial of Alemtuzumab (Campath) and Dose-Adjusted EPOCH-Rituximab (DA-EPOCH-R) in Relapsed or Refractory Diffuse Large B-Cell and Hodgkin LymphomasCompleted Study; data analyses ongoing18-125 YearsNCI 9
09-M-0176Functional Relevance of Dopamine Receptors in Healthy Controls and Patients with Schizophrenia: Characterization through [11C]NNC-112 and [18F]Fallypride Positron Emission TomographyParticipants currently recruited/enrolled18-90 YearsNIMH 9
09-I-0200A Phase I Study of MozobilTM in the Treatment of Patients with WHIMSParticipants currently recruited/enrolled18-75 YearsNIAIDNeutropenia
09-DK-0097Vitamin E Pharmacokinetics and Biomarkers in Normal and Obese WomenCompleted Study; data analyses ongoing18-55 YearsNIDDK9
09-C-0139A Pilot Study of Vaccination with Epitope-Enhanced TARP Peptide and TARP Peptide-Pulsed Dendritic Cells in the Treatment of Stage D0 Prostate CancerCompleted Study; data analyses ongoing18-125 YearsNCI 9
09-C-0120An Exploratory Evaluation of Biomarkers in Blister Fluid in Healthy Volunteers and Irradiated SkinCompleted Study; data analyses ongoing18-125 YearsNCI 9
09-C-0100A Pilot Study of High Dose Rate Brachytherapy in The Radiation Oncology BranchParticipants currently recruited/enrolled18-125 YearsNCI 9
09-C-0025Phase II Trial of LMB-2, Fludarabine and Cyclophosphamide for Adult T-Cell LeukemiaNo longer recruiting/follow-up only18-125 YearsNCI 9
09-C-0024A Phase I Study of Quadrivalent Human Papilloma Virus (HPV) (Types 6, 11, 16, 18) Recombinant Vaccine in HIV-Infected and HIV-Negative Pre-Adolescents, Adolescents and Young AdultsCompleted Study; data analyses ongoing12-26 YearsNCI 9
09-C-0005Randomized Trial of Cladribine (CdA) with Simultaneous or Delayed Rituximab to Eliminate Hairy Cell Leukemia Minimal Residual DiseaseParticipants currently recruited/enrolled18-125 YearsNCI 9
08-H-0046Co-Infusion of Umbilical Cord Blood and Haploidentical CD34+ Cells Following Nonmyeloablative Conditioning as Treatment for Severe Aplastic Anemia and MDS Associated with Severe Neutropenia Refractory to Immunosuppressive TherapyCompleted Study; data analyses ongoing4-75 YearsNHLBINeutropenia
08-DK-N191The Effects of Transcranial Direct Current Stimulation (TDCS) on Food Intake and Weight LossParticipants currently recruited/enrolled18-60 YearsNIDDK9
08-C-0214A Pilot Study to Evaluate Neuropsychological Outcome Measures and their Relationship with Prognosis in Patients Receiving Radiation Therapy for Brain MetastasesParticipants currently recruited/enrolled18-125 YearsNCI 9
08-C-0130A Phase II Trial of Peginterferon alfa-2b (PEG-Intron) for Neurofibromatosis Type 1 Related Unresectable, Symptomatic or Life-Threatening Plexiform NeurofibromasCompleted Study; data analyses ongoing0-21 YearsNCI Congenital
07-N-0190Neurobiological Studies of Functional Movement Disorders and Non-Epileptic SeizuresNo longer recruiting/follow-up only18-125 YearsNINDS9
07-H-0005Pilot Study of Topical Dexamethasone 0.01% Solution for Prevention of Oral Chronic Graft Versus Host DiseaseCompleted Study; data analyses ongoing12-110 YearsNHLBI9
07-E-0012Rituximab in the Treatment of Refractory Adult and Juvenile Dermatomyositis (DM) and Adult Polymyositis (PM)Completed Study; data analyses ongoing2-125 YearsNIEHS9
07-C-0121Phase 2 Study of the C-Met RTK Inhibitor Foretinib (Formerly GSK 1363089) in Subjects with Papillary Renal Cell Carcinoma (PRC)Completed Study; data analyses ongoing18-125 YearsNCI 9
06-H-0190Treatment of T-Large Granular Lymphocyte (T-LGL) Lymphoproliferative Disorders with Alemtuzumab (Campath)Completed Study; data analyses ongoing18-85 YearsNHLBINeutropenia
06-H-0072Atorvastatin as a Disease Modifying Agent in Stage II and III Pulmonary Sarcoidosis: A Randomized, Double-Blind, Placebo-Controlled TrialCompleted Study; data analyses ongoing18-70 YearsNHLBI9
06-CH-0011Natural History Study of Patients with Excess AndrogenParticipants currently recruited/enrolled0-99 YearsNICHDCongenital
05-C-0252Phase III Randomized Study of R-CHOP v. Dose-Adjusted EPOCH-R with Molecular Profiling in Untreated de Novo Diffuse Large B-Cell LymphomasCompleted Study; data analyses ongoing18-125 YearsNCI 9
04-N-0056The Neural Immune Mechanisms and Genetic Influences on Chronic Pelvic Pain in Women with EndometriosisCompleted Study; data analyses ongoing18-50 YearsNINDS9
04-E-0053Personalized Environment and Genes StudyParticipants currently recruited/enrolled18-130 YearsNIEHS9
03-H-0170Nonmyeloablative Allogeneic Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation For Severe Congenital Anemias Including Sickle Cell Disease (SCD) and Beta-ThalassemiaParticipants currently recruited/enrolled2-125 YearsNHLBICongenital
03-EI-0033X-Linked Juvenile Retinoschisis - Clinical and Molecular StudiesParticipants currently recruited/enrolled0-125 YearsNEI 9
02-I-0147Genetic Studies of Chronic Active Epstein-Barr Virus InfectionParticipants currently recruited/enrolled1-125 YearsNIAID9
02-I-0080The Gemini Study: Study of the Long-Term Safety and Persistence of Cells Following Cell Transfers or Gene Therapy in Identical Twins Discordant for HIV InfectionNo longer recruiting/follow-up only18-125 YearsNIAID9
02-CC-0266Acute Cardiac Allograft Cellular Rejection and Cardiac Allograft Vasculopathy: Identification of Diagnostic Biomarkers and Target Pathways for Preventive TherapyCompleted Study; data analyses ongoing18-125 YearsCC 9
01-M-0232Positron Emission Tomography (PET) Scanning in Dopamine Disorders: Parkinson's Disease and SchizophreniaParticipants currently recruited/enrolled18-90 YearsNIMH 9
01-CC-0231A Prospective Study of Transfusion-Transmitted InfectionsCompleted Study; data analyses ongoing0-125 YearsCC 9
01-C-0009Breast Imaging Screening Studies in Women at High Genetic Risk of Breast Cancer: Annual Follow-up StudyCompleted Study; data analyses ongoing18-100 YearsNCI 9
00-N-0082Characterization of Brain Morphology and Activity Using Functional and Anatomical MRI ContrastParticipants currently recruited/enrolled18-125 YearsNINDS9
00-HG-0209Molecular and Clinical Studies of Primary Immunodeficiency DiseasesNo longer recruiting/follow-up only3-125 YearsNHGRI9
99-I-0084Studies of Human Pneumocystis InfectionParticipants currently recruited/enrolled3-99 YearsNIAID9
99-H-0076Asthma Sample Collection ProtocolParticipants currently recruited/enrolled18-125 YearsNHLBI9
99-H-0050Non-Myeloablative Allogeneic Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Hematologic Malignancies in High Risk Patients and in Patients with Debilitating Hematologic DiseasesCompleted Study; data analyses ongoing2-80 YearsNHLBI9
99-DK-0002Diabetes and Heart Disease Risk in BlacksParticipants currently recruited/enrolled18-70 YearsNIDDK9
99-CH-0103Evaluation of Women and Men with Endocrine and Reproductive-Related ConditionsClinical hold/Recruitment or enrollment suspended1-85 YearsNICHD9
99-CC-0168Collection and Distribution of Blood Components from Healthy Donors for In Vitro Research UseParticipants currently recruited/enrolled18-125 YearsCC 9
99-C-0128Evaluation for NCI Surgery Branch Clinical Research ProtocolsParticipants currently recruited/enrolled18-125 YearsNCI 9
99-C-0099Examination of Clinical and Laboratory Abnormalities in Patients with Defective DNA Repair: Xeroderma Pigmentosum, Cockayne Syndrome, or TrichothiodystrophyParticipants currently recruited/enrolled0-125 YearsNCI 9
98-N-0047Immuno-Virological Evaluation of Human T Cell Leukemia Virus Type-1 Associated Myelopathy (HAM/TSP)Participants currently recruited/enrolled18-125 YearsNINDS9
98-D-0145Screening and Natural History of Patients with Polyostotic Fibrous Dysplasia and the McCune-Albright SyndromeParticipants currently recruited/enrolled0-100 YearsNIDCR9
98-CH-0081Clinical and Basic Investigations into Smith-Lemli-Opitz SyndromeCompleted Study; data analyses ongoing0-125 YearsNICHD9
98-CC-0019Volunteer Scanning on MRParticipants currently recruited/enrolled18-125 YearsCC 9
97-I-0096Evaluation, Treatment, and Monitoring of Patients With Known or Suspected Parasitic InfectionParticipants currently recruited/enrolled3-125 YearsNIAID9
97-HG-0192Genetic Studies in the Amish and MennonitesCompleted Study; data analyses ongoing18-125 YearsNHGRI9
97-DC-0057Genetic Studies of StutteringCompleted Study; data analyses ongoing6-125 YearsNIDCD9
97-CH-0076A Clinical and Genetic Investigation of Pituitary and HYPOTHALAMIC Tumors and Related DisordersParticipants currently recruited/enrolled3-70 YearsNICHD9
97-CH-0064Evaluation and Intervention for Ambulation, Growth, and Basilar Invagination in Osteogenesis ImperfectaCompleted Study; data analyses ongoing0-10 YearsNICHD9
97-C-0147Collection of Serum and Tissue Samples from Patients with Biopsy-Proved or Suspected Malignant DiseasesParticipants currently recruited/enrolled2-125 YearsNCI 9
96-I-0052A Comprehensive Clinical, Microbiological and Immunological Assessment of Patients with Suspected Post Treatment Lyme Disease Syndrome and Selected Control PopulationsParticipants currently recruited/enrolled13-125 YearsNIAID9
96-H-0100Role of Genetic Factors in the Pathogenesis of Lung DiseaseParticipants currently recruited/enrolled2-90 YearsNHLBI9
96-H-0049Use of Granulocyte Colony Stimulating Factor (G-CSF) Mobilized Leukapheresis Collections from Healthy Volunteers to Develop Improved Methods of Stem Cell and Lymphocyte Selection for Allogeneic TransplantationParticipants currently recruited/enrolled18-60 YearsNHLBI9
96-C-0071Follow-up for Patients Previously Enrolled on the Center for Cancer Research ProtocolsNo longer recruiting/follow-up only0-125 YearsNCI 9
96-AR-0102Evaluation and Treatment of Subjects with Dermatologic DiseasesParticipants currently recruited/enrolled0-125 YearsNIAMS9
96-AR-0097The Acquisition of Blood and Skin Samples from Patient Volunteers to Support Research Activities on Dermatologic and Other DiseasesNo longer recruiting/follow-up only18-125 YearsNIAMS9
95-M-0150A Neurobiological Investigation of Patients with Schizophrenia Spectrum Disorders and Their SiblingsParticipants currently recruited/enrolled18-55 YearsNIMH 9
95-M-0097An Endocrine Model for Postpartum Mood DisordersParticipants currently recruited/enrolled18-50 YearsNIMH 9
95-I-0066Genetic Analysis of Immune DisordersParticipants currently recruited/enrolled0-125 YearsNIAID9
95-I-0027Virologic and Immunologic Evaluation of Lymph Node, Tonsillar and Intestinal Biopsies, and Bronchoalveolar Lavage FluidParticipants currently recruited/enrolled18-125 YearsNIAID9
95-HG-0193Clinical and Basic Investigations into Hermansky-Pudlak SyndromeParticipants currently recruited/enrolled0-125 YearsNHGRI9
95-H-0186Characterization of the Pathogenesis of Lymphangioleiomyomatosis (LAM)Participants currently recruited/enrolled16-125 YearsNHLBI9
95-CH-0059Definition of the Genotype and Clinical Phenotype of Primary Pigmented Nodular Adrenocortical Disease (PPNAD), Carney Complex, Peutz-Jeghers Syndrome and Related ConditionsCompleted Study; data analyses ongoing3-70 YearsNICHD9
94-I-0079Eosinophil Activation and Function in Parasitic Infections and Other Conditions with Increased Tissue or Peripheral Blood Eosinophilia in HumansParticipants currently recruited/enrolled1-100 YearsNIAID9
94-I-0073Recruitment and Apheresis Collection of Peripheral Blood Hematopoietic Stem Cells, Mononuclear Cells and GranulocytesParticipants currently recruited/enrolled18-70 YearsNIAID9
94-HG-0105An Exploratory Study of the Genetics, Pathophysiology, and Natural History of Autoinflammatory DiseasesParticipants currently recruited/enrolled0-125 YearsNHGRI9
94-E-0165Studies in the Natural History and Pathogenesis of Childhood-Onset and Adult-Onset Idiopathic Inflammatory MyopathiesParticipants currently recruited/enrolled2-100 YearsNIEHS9
94-DK-0133Genetic Markers for Focal Segmental GlomerulosclerosisCompleted Study; data analyses ongoing1-125 YearsNIDDK9
94-DK-0127Pathogenesis of GlomerulosclerosisCompleted Study; data analyses ongoing2-125 YearsNIDDK9
94-C-0074Treatment and Natural History Study of Lymphomatoid GranulomatosisParticipants currently recruited/enrolled12-125 YearsNCI 9
94-AR-0066Studies of the Pathogenesis and Natural History of Systemic Lupus Erythematosus (SLE)Participants currently recruited/enrolled9-125 YearsNIAMS9
93-N-0202Diagnosis and Natural History Protocol for Patients with Different Neurological ConditionsParticipants currently recruited/enrolled2-125 YearsNINDS9
93-M-0170Regional Cerebral Blood Flow Studies of Object Perception, Identification, Localization, and MemoryParticipants currently recruited/enrolled18-65 YearsNIMH 9
93-I-0119Detection and Characterization of Host Defense DefectsParticipants currently recruited/enrolled0-125 YearsNIAID9
93-I-0106Cryptococcosis in Previously Healthy AdultsParticipants currently recruited/enrolled18-125 YearsNIAID9
93-I-0086Evaluation and Long-Term Follow-Up of Patients with Acute or Chronic Inflammatory DisordersEnrolling by Invitation2-125 YearsNIAID9
93-I-0063Study of the Immunopathogenesis, Natural History, and Genetics of Autoimmune Lymphoproliferative Syndrome (ALPS) Associated with an Expansion of CD4-8-/TCR alpha/beta+ T CellsParticipants currently recruited/enrolled0-99 YearsNIAID9
93-C-0133Dose-Adjusted EPOCH Chemotherapy and Rituximab (CD20+) in Adults and Children with Previously Untreated Patients with Aggressive Non-Hodgkin's LymphomaNo longer recruiting/follow-up only12-125 YearsNCI 9
92-M-0174The Central Nervous System Effects of Pharmacologically Induced Hypogonadotropic Hypogonadism with and without Estrogen and Progesterone ReplacementCompleted Study; data analyses ongoing18-50 YearsNIMH 9
92-I-0125A Study of Viral Burden in Peripheral Blood Versus Lymphoid and Bone Marrow Tissue in HIV-Infected IndividualsParticipants currently recruited/enrolled18-125 YearsNIAID9
92-DK-0156Studies of Immunologically-Mediated Kidney DiseasesParticipants currently recruited/enrolled10-125 YearsNIDDK9
92-DK-0033Pharmacokinetics and Biodistribution of Ascorbic Acid in Healthy Human SubjectsCompleted Study; data analyses ongoing18-35 YearsNIDDK9
92-CH-0034Studies of Growth Deficiency and Growth Hormone Treatment in Children with Osteogenesis Imperfecta Types III and IVCompleted Study; data analyses ongoing3-16 YearsNICHD9
91-I-0140Studies of the Pathogenesis of HIV Infection in Human Peripheral Blood Cells and/or Body Fluids in HIV-Infected and HIV-Uninfected VolunteersParticipants currently recruited/enrolled18-125 YearsNIAID9
91-DK-0214Evaluation of Patients with Liver DiseaseParticipants currently recruited/enrolled2-125 YearsNIDDK9
91-DK-0066Fasting Hypoglycemia: Diagnosis and TreatmentParticipants currently recruited/enrolled18-120 YearsNIDDK9
91-CC-0117Epidemiology, Infectivity and Natural History of Hepatitis C Virus Infection in a Blood Donor PopulationNo longer recruiting/follow-up only18-125 YearsCC 9
91-AR-0196Studies on the Natural History and Pathogenesis of Polymyositis, Dermatomyositis, and Related DiseasesParticipants currently recruited/enrolled16-125 YearsNIAMS9
90-M-0088The Treatment of Menstrually-Related Mood Disorders with the Gonadotropin Releasing Hormone (GnRH) Agonist, Depot Leuprolide Acetate (Lupron)Completed Study; data analyses ongoing18-45 YearsNIMH 9
90-M-0014Studies of Frontal Lobe Function During Cognitive Stimulation as Measured with Oxygen-15 Water Positron Emission Tomography in Normal Subjects and Patients with Neuropsychiatric DisordersCompleted Study; data analyses ongoing18-90 YearsNIMH 9
90-DK-0137Evaluation of the Gastrinoma in Patients with Zollinger-Ellison SyndromeCompleted Study; data analyses ongoing18-100 YearsNIDDK9
90-CC-0168A Rigid Body Database on Human MovementParticipants currently recruited/enrolled0-125 YearsCC 9
89-M-0006Brain Imaging of Childhood Onset Psychiatric Disorders, Endocrine Disorders and Healthy VolunteersParticipants currently recruited/enrolled3-125 YearsNIMH Congenital
81-I-0164Procedures to Obtain Plasma, Lymphocytes, or Other Specimens for Research StudiesParticipants currently recruited/enrolled18-125 YearsNIAID9
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