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22 Studies found from all possible combinations of your search terms. Select a protocol that you wish to review.
Protocol Number
Title
Protocol Status
Min-Max Age
Institute
Keywords
001696-C
Surveillance for Malignant Transformation of Neurofibromatosis Type 1 (NF1) Related Peripheral Nerve Sheath Tumors (PNST)
Recruitment has not started
3-120 Years
NCI
Neurofibromatosis
000696-C
A Phase III, Multicenter, International Study with a Parallel, Randomized, Double-blind, Placebo-controlled, 2 Arm Design to Assess the Efficacy and Safety of Selumetinib in Adult Participants with NF1 who have Symptomatic, Inoperable Plexiform Neurofibr
Participants currently recruited/enrolled
18-120 Years
NCI
Neurofibromatosis
000657-C
Acceptance and Commitment Therapy for Caregivers of Children with a RASopathy: An Internal Pilot Feasibility Study and Follow-up Phase III Randomized Controlled Trial
Participants currently recruited/enrolled
18-125 Years
NCI
Neurofibromatosis
21-C-0011
A Phase 0/I/II Study of the Cyclin-Dependent Kinase(CDK)4/6 Inhibitor Abemaciclib for Neurofibromatosis Type 1 (NF1) Related Atypical Neurofibromas
Participants currently recruited/enrolled
12-125 Years
NCI
Neurofibromatosis
19-C-0061
A Phase 2 Trial of the MEK Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in Combination with the mTOR Inhibitor Sirolimus for Patients with Unresectable or Metastatic Malignant Peripheral Nerve Sheath Tumors
Completed Study; data analyses ongoing
12-125 Years
NCI
Neurofibromatosis
18-C-0102
Pilot Study of the MEK1/2 Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) for Adults with Neurofibromatosis Type 1 (NF1) and Cutaneous Neurofibromas (cNF)
Completed Study; data analyses ongoing
18-125 Years
NCI
Neurofibromatosis
18-C-0093
Pilot Study of Medication Adherence in Children, Adolescents, and Adults with Neurofibromatosis Type 1 (NF1) on Clinical Treatment Trials
Completed Study; data analyses ongoing
3-125 Years
NCI
Neurofibromatosis
16-C-0043
Phase II Trial of the MEK1/2 Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate in Adults with Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas
No longer recruiting/follow-up only
18-125 Years
NCI
Neurofibromatosis
15-C-0195
Development and Validation of Patient Reported Outcome (PRO) Measures for Individuals with Neurofibromatosis 1 (NF1) and Plexiform Neurofibromas (pNFs)
Participants currently recruited/enrolled
5-125 Years
NCI
Neurofibromatosis
15-C-0142
Acceptance and Commitment Training for Adolescents and Adults with Neurofibromatosis Type 1, Plexiform Neurofibromas, and Chronic Pain: A Phase III Clinical Trial
Completed Study; data analyses ongoing
16-59 Years
NCI
Neurofibromatosis
15-C-0093
Phase I Trial of TURALIO (pexidartinib, PLX3397) in Children and Young Adults with Refractory Leukemias and Refractory Solid Tumors Including Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PN) and Tenosynovial Giant Cell Tumor (TGCT
Participants currently recruited/enrolled
3-35 Years
NCI
Neurofibromatosis
15-C-0019
The Impact of Ras/MAPK Signaling Pathway-Targeted Therapies on Neurocognitive Functioning in Individuals with NF1
Completed Study; data analyses ongoing
4-99 Years
NCI
Neurofibromatosis
14-C-0163
Transformation of Plexiform Neurofibromas to Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis Type 1: Clinical, Histopathologic, and Genomic Analysis
Completed Study; data analyses ongoing
10-125 Years
NCI
Neurofibromatosis
12-C-0206
Understanding the Perceived Influence of Childhood Cancer and NF1 on the Parents' Marital/Partner Relationship: A Descriptive Study
Completed Study; data analyses ongoing
18-125 Years
NCI
Neurofibromatosis
12-C-0160
Validation of the English Version of the Pain Interference Index and the Pain Rating Scale in Children, Adolescents, and Adults with Chronic Illness and their Parents
Completed Study; data analyses ongoing
18-125 Years
NCI
Neurofibromatosis
11-C-0161
A Phase I/II Study of the Mitogen Activated Protein Kinase Kinase (MEK) 1 Inhibitor Selumetinib (AZD6244; Hydrogen Sulfate in Children with Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas (PN)
No longer recruiting/follow-up only
2-18 Years
NCI
Neurofibromatosis
08-N-0044
A Prospective Natural History Study of Patients with Neurofibromatosis Type 2 (NF2).
Participants currently recruited/enrolled
8-75 Years
NINDS
Neurofibromatosis
08-C-0130
A Phase II Trial of Peginterferon alfa-2b (PEG-Intron) for Neurofibromatosis Type 1 Related Unresectable, Symptomatic or Life-Threatening Plexiform Neurofibromas
Completed Study; data analyses ongoing
0-21 Years
NCI
Neurofibromatosis
08-C-0079
Natural History Study and Longitudinal Assessment of Children, Adolescents, and Adults with Neurofibromatosis Type 1
No longer recruiting/follow-up only
0-125 Years
NCI
Neurofibromatosis
07-C-0110
Analysis of Stored Data Collected from Individuals Administered Neurobehavioral Assessments on IRB-Approved Protocols
Enrolling by Invitation
0-125 Years
NCI
Neurofibromatosis
06-C-0134
Natural History and Biology of Dermal Neurofibromas in Neurofibromatosis Type 1
Completed Study; data analyses ongoing
20-99 Years
NCI
Neurofibromatosis
05-C-0152
Variation in Gene Expression in Neurofibromatosis Type 1
Completed Study; data analyses ongoing
2-100 Years
NCI
Neurofibromatosis