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280 Studies found from all possible combinations of your search terms. Select a protocol that you wish to review.
Please note that only the first 5 legal search words are being processed.
Protocol Number
Title
Protocol Status
Min-Max Age
Institute
Keywords
20-H-0141
Long-term Follow-up of Subjects With Sickle Cell Disease Treated With Ex Vivo Gene Therapy Using Autologous Hematopoietic Stem Cells Transduced With a Lentiviral Vector
Enrolling by Invitation
18-125 Years
NHLBI
Brain Iron
17-N-0131
Investigating Complex Neurodegenerative Disorders Related to Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
Participants currently recruited/enrolled
18-125 Years
NINDS
Brain Accumulation
16-E-0157
CaREFREE Study (Calorie Restriction, Environment and Fitness: Reproductive Effects Evaluation Study)
Completed Study; data analyses ongoing
18-28 Years
NIEHS
Brain Iron
15-N-0156
In Vivo Characterization of Inflammation with Ferumoxytol, an Ultrasmall Superparamagnetic Iron Oxide Nanoparticle, on 7 Tesla Magnetic Resonance Imaging
Completed Study; data analyses ongoing
18-70 Years
NINDS
Brain Iron
13-CH-0001
Intrathecal 2-Hydroxypropyl-B-Cyclodextrin in Patients with Niemann-Pick Disease, Type C1
Completed Study; data analyses ongoing
2-125 Years
NICHD
Neurodegeneration Brain
10-CH-0198
Testing and Calibration of Non-Invasive Optical Imaging Technology for Functional Brain Imaging
Participants currently recruited/enrolled
18-125 Years
NICHD
Brain Iron
02-HG-0107
Natural History of Glycosphingolipid Storage Disorders and Glycoprotein Disorders
Participants currently recruited/enrolled
0-125 Years
NHGRI
Neurodegeneration Brain
001074-CH
Characterization of Dysmorphology in Subjects with Creatine Transporter Deficiency
Participants currently recruited/enrolled
2-40 Years
NICHD
Brain
001018-CH
Establishment of Genomic and Phenotypic Database for Niemann-Pick Disease, Type C
Participants currently recruited/enrolled
0-125 Years
NICHD
Brain
000978-M
State-Dependent Interoception, Value-Based Decision-Making, and Introspection
Recruitment has not started
18-55 Years
NIMH
Brain
000942-M
A Cognitive Test Battery for Intellectual Disabilities
Participants currently recruited/enrolled
4-125 Years
NIMH
Brain
000862-CH
Pilot Study of the Use of Functional Near-Infrared Spectroscopy (fNIRS) Combined with Diffuse Correlation Spectroscopy (DCS) in Neurocognitive Disease as Compared to Healthy Neurotypical Controls
Participants currently recruited/enrolled
0-125 Years
NICHD
Brain
000860-C
A Phase I/II Study of Zotiraciclib for Recurrent High-Grade Gliomas with Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations
Recruitment has not started
18-125 Years
NCI
Brain
000824-M
[11C]-(R)-Rolipram to Measure cAMP Signaling Before and After Ketamine
Enrolling by Invitation
18-70 Years
NIMH
Brain
000784-N
Assessing and Improving Quantitative Magnetic Resonance Imaging Metrics in Human Subjects
Participants currently recruited/enrolled
18-125 Years
NINDS
Brain
000776-M
An Open Trial of Transcranial Magnetic Stimulation for Youth with Treatment-Resistant Major Depressive Disorder
Recruitment has not started
13-17 Years
NIMH
Brain
000754-M
NIMH Rhythms and Blues Study: A Prospective Natural History Study of Motor Activity, Mood States, and Bipolar Disorder
Participants currently recruited/enrolled
12-70 Years
NIMH
Brain
000744-HG
Development of Virtual Reality-based Interventions to Strengthen Cognitive Skillsets Related to Attention Deficit Hyperactivity Disorder (ADHD): A Randomized Controlled Phase II Trial
Recruitment has not started
7-14 Years
NHGRI
Brain
000736-CC
Imaging Characterization of the Biomechanical Coupling of Brain and Skull: An Observational Study
Participants currently recruited/enrolled
21-65 Years
CC
Brain
000711-N
Immunotherapy for Neurological Post-Acute Sequelae of SARS-CoV-2 (IN-PASC)
Enrolling by Invitation
18-125 Years
NINDS
Brain
000687-I
VRC 322/DMID 21-0016: A Phase I, Dose Escalation, Open-Label Clinical Trial to Evaluate Safety, Tolerability and Immunogenicity of a Nipah Virus (NiV) mRNA Vaccine, mRNA-1215, in Healthy Adults
Participants currently recruited/enrolled
18-60 Years
NIAID
Brain
000686-CH
Intrathecal 2-Hydroxypropyl-Beta-Cyclodextrin for Neurological Decline in Patients with Niemann-Pick Disease Type C1
Participants currently recruited/enrolled
18-125 Years
NICHD
Brain
000678-C
Rare Tumors and Cancer Predisposition in Individuals and Families
Participants currently recruited/enrolled
0-125 Years
NCI
Brain
000676-M
[18F]PF-06445974 to Image PDE4B in Major Depressive Disorder Using PET
Participants currently recruited/enrolled
18-70 Years
NIMH
Brain
000674-M
Assessment of [18F]SF12051 for Imaging the 18-kDa Translocator Protein (TSPO) in Brain and Whole Body of Healthy Subjects
Participants currently recruited/enrolled
18-99 Years
NIMH
Brain
000642-N
Phase II Trial of Non-Invasive Intermittent Theta Burst Stimulation of the Dorsolateral Prefrontal Cortex in Functional Movement Disorders
Participants currently recruited/enrolled
18-80 Years
NINDS
Brain
000631-C
Investigation of the Cognitive Aftereffects of Neurotoxicity in Children and Young Adults with Relapsed/Refractory Hematologic Malignancies who Receive CAR T-cell Therapy
Recruitment has not started
5-125 Years
NCI
Brain
000585-CH
An Open-label Safety, Pharmacokinetic, and Efficacy Study of Miglustat for the Treatment of CLN3 Disease in Patients 17 Years of Age and Older
Participants currently recruited/enrolled
17-125 Years
NICHD
Brain
000539-H
Addition of JSP191 (c-kit antibody) to Non-myeloablative Hematopoietic Cell Transplantation For Sickle Cell Disease and Beta-Thalassemia
Participants currently recruited/enrolled
4-100 Years
NHLBI
Brain
000527-M
CNS Correlates of Extended Sleep Restriction
Participants currently recruited/enrolled
18-39 Years
NIMH
Brain
000483-M
PET Imaging of Cyclooxygenases in Multiple Sclerosis
Participants currently recruited/enrolled
18-99 Years
NIMH
Brain
000479-H
Observational Study to Deeply Phenotype Major Organs in Sickle Cell Disease After Curative Therapies
Participants currently recruited/enrolled
18-125 Years
NHLBI
Brain
000476-E
The Investigation of Vitamin D and Menstrual Cycles Trial: A Phase II Clinical trial
Participants currently recruited/enrolled
19-40 Years
NIEHS
Brain
000421-AA
Individual Variations of Taste and Smell Perception in Alcohol Use Disorder (AUD)
Recruitment has not started
18-65 Years
NIAAA
Brain
000417-CC
Characterization of the Nociception Phenotype in Individuals with Intellectual Disability
Clinical hold/Recruitment or enrollment suspended
8-30 Years
CC
Brain
000413-H
Natural History study of CADASIL
Participants currently recruited/enrolled
18-100 Years
NHLBI
Brain
000406-AA
Addictions Neuroclinical Assessment
Enrolling by Invitation
18-125 Years
NIAAA
Brain
000378-M
Identifying decision making parameters in healthy volunteers (HV) and anxiety patients (AD)
Completed Study; data analyses ongoing
18-50 Years
NIMH
Brain
000337-C
Natural History Study of KSHV-Associated Multicentric Castleman's Disease
Participants currently recruited/enrolled
18-125 Years
NCI
Brain
000317-C
A Phase II, Open-Label Trial of PT-112 in Subjects with Thymoma and Thymic Carcinoma
Participants currently recruited/enrolled
18-125 Years
NCI
Brain
000254-C
A Phase II Trial of the Superenhancer Inhibitor Minnelide in Advanced Refractory Adenosquamous Carcinoma of the Pancreas (ASCP)
Participants currently recruited/enrolled
18-125 Years
NCI
Brain
000224-CH
Development of a Wearable Point of Care Monitoring Device for Pediatric Obstructive Sleep Apnea
Participants currently recruited/enrolled
3-12 Years
NICHD
Brain
000196-N
Task-dependent Effects of TMS on the Neural Biomarkers of Episodic Memory
Participants currently recruited/enrolled
18-40 Years
NINDS
Brain
000193-C
Phase 1 Study of Copanlisib with Dose-adjusted EPOCH-R in Relapsed and Refractory Burkitt Lymphoma and other High-Grade B-cell Lymphomas
Clinical hold/Recruitment or enrollment suspended
18-125 Years
NCI
Brain
000141-DC
Deep Phenotyping of Hearing Instability Disorders: Cohort Establishment, Biomarker Identification, Development of Novel Phenotyping Measures, and Discovery of Therapeutic Targets
Participants currently recruited/enrolled
18-80 Years
NIDCD
Brain
000126-N
A Pilot Study of NT-I7, a Long-Acting Recombinant IL-7 Molecule, as an Immune Reconstitution Strategy for Lymphopenia in Patients with Progressive Multifocal Leukoencephalopathy
Participants currently recruited/enrolled
18-125 Years
NINDS
Brain
000101-M
An Investigation of the Antidepressant Effects of the mGlu2/3 receptor antagonist TS-161 in Treatment-Resistant Depression
Participants currently recruited/enrolled
18-65 Years
NIMH
Brain
000094-N
An Observational Study of Neurologic Function After COVID -19 Infection
No longer recruiting/follow-up only
18-125 Years
NINDS
Brain
000085-C
Assessing Sleep and Circadian Rhythms in Primary Brain Tumors Patients: An Observational Study
Enrolling by Invitation
18-99 Years
NCI
Brain
000079-DK
The Role of 68-Gallium-DOTATATE-PET/CT in the Imaging of Metastatic Thyroid Cancer
Participants currently recruited/enrolled
18-125 Years
NIDDK
Brain
000051-N
NIH Investigative Deep Phenotyping Study of Gulf War Veteran Health (Project NIH IN-DEPTH)
Participants currently recruited/enrolled
48-70 Years
NINDS
Brain
22-C-0003
Feasibility of Evaluating Abemaciclib Neuropharmacokinetics of Diffuse Midline Glioma Using Intratumoral Microdialysis
Participants currently recruited/enrolled
18-39 Years
NCI
Brain
21-N-0016
Phase I/II Study of Teriflunomide in HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis
Participants currently recruited/enrolled
18-125 Years
NINDS
Brain
21-N-0010
A Phase 2 Clinical Trial of Tolebrutinib, a Brain-penetrant Bruton's Tyrosine Kinase Inhibitor, for the Modulation of Chronically Inflamed White Matter Lesions in Multiple Sclerosis
No longer recruiting/follow-up only
18-125 Years
NINDS
Brain
21-M-0031
A Feasibility Study of Transcranial Electric Stimulation Therapy (TEST) for treatment resistant depression (TRD)
Participants currently recruited/enrolled
25-64 Years
NIMH
Brain
21-M-0018
Characterization of an Optically Pumped Magnetometer (OPM) Magnetoencephalography (MEG) Array
Participants currently recruited/enrolled
18-65 Years
NIMH
Brain
21-C-0019
Phase I Study of Anti-CD22 Chimeric Receptor T Cells in Patients with Relapsed/Refractory Hairy Cell Leukemia and Variant
Participants currently recruited/enrolled
18-125 Years
NCI
Brain
21-C-0017
Magnetic Resonance Image (MRI) Guided High Energy Ultrasound for Focal Prostate Cancer Ablation
Recruitment has not started
18-125 Years
NCI
Brain
21-C-0015
Phase II Trial Evaluating the Association of Peripheral Blood Immunologic Response to Therapeutic Response to Adjuvant Treatment with Immune Checkpoint Inhibition (ICI) in Patients with Newly Diagnosed Glioblastoma or Gliosarcoma
Participants currently recruited/enrolled
18-125 Years
NCI
Brain
21-C-0007
A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon Cancers
Participants currently recruited/enrolled
18-125 Years
NCI
Brain
20-N-0105
Layer-specific Contribution to Consolidation of Skill Learning in the Primary Motor Cortex
Participants currently recruited/enrolled
18-50 Years
NINDS
Brain
20-N-0077
Study of Volition: Behavioral analysis and Clinical Neurophysiological Analysis
Participants currently recruited/enrolled
25-45 Years
NINDS
Brain
20-N-0060
Mechanisms Underlying the Beneficial Effects of Naps on Motor Learning
Participants currently recruited/enrolled
18-80 Years
NINDS
Brain
20-N-0048
Corticotrophin-Releasing Hormone (CRH) Stimulation for 18F-FDG-PET Detection of Pituitary Adenoma in Cushing's Disease
Recruitment has not started
8-125 Years
NINDS
Brain
20-M-0166
Electrophysiologic Sleep Phenotyping and Sleep-Dependent Neuro-maturation in Clinical and Healthy Pediatric Populations
Participants currently recruited/enrolled
0-8 Years
NIMH
Brain
20-M-0159
Role of GABAergic Transmission in Auditory Processing in Autism Spectrum Disorder
Participants currently recruited/enrolled
14-25 Years
NIMH
Brain
20-M-0157
PET Imaging of Cyclooxygenase in Participants with Major Depressive Disorder (MDD)
Participants currently recruited/enrolled
18-70 Years
NIMH
Brain
20-M-0082
Phase 1 Study: PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease
Participants currently recruited/enrolled
18-99 Years
NIMH
Brain
20-HG-0156
A Multicenter, Multinational, Randomized, Double-Blind, Placebo-Controlled Study to Assess The Efficacy, Pharmacodynamics, Pharmacokinetics, Safety, and Tolerability of Venglustat in Late-Onset GM2 Gangliosidosis (Tay-Sachs Disease And Sandhoff Disease)
No longer recruiting/follow-up only
2-125 Years
NHGRI
Neurodegeneration
20-HG-0147
An Observational Study of the Developing Brain, Impulsivity and Compulsivity.
Participants currently recruited/enrolled
6-80 Years
NHGRI
Brain
20-H-0021
Treatment of Refractory Diamond-Blackfan Anemia with Eltrombopag
No longer recruiting/follow-up only
2-125 Years
NHLBI
Iron
20-CC-0113
Cardiopulmonary Inflammation and Multi-System Imaging During the Clinical Course of COVID-19 Infection in Asymptomatic and Symptomatic Persons (COVID ARC 19)
No longer recruiting/follow-up only
18-80 Years
CC
Brain
20-C-0127
A Phase 1 Study of Romidepsin, CC-486 (5-azacitidine), dexamethasone, and lenalidomide (RAdR) for relapsed/refractory T-cell malignancies
Participants currently recruited/enrolled
18-125 Years
NCI
Brain
20-C-0107
Clinical, Genetic, and Epidemiologic Study of Children and Adults with RASopathies
Participants currently recruited/enrolled
0-125 Years
NCI
Brain
20-C-0106
Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients with BAP1 Tumor Predisposition Syndrome
Participants currently recruited/enrolled
30-125 Years
NCI
Brain
20-C-0069
A First-In-Human Phase I Single-Agent Dose-Escalation, Food Effect and Dose Expansion Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms
Participants currently recruited/enrolled
18-125 Years
NCI
Brain
20-C-0065
A Phase II Feasibility Trial Using Immersive Virtual Reality (VR) at the Time of Clinical Evaluation to Improve Psychological Distress and Anxiety in Primary Brain Tumor (PBT) Patients
Participants currently recruited/enrolled
18-125 Years
NCI
Brain
20-C-0027
A Phase I Clinical Trial of Selinexor (KPT-330) in Combination with Temozolomide and Radiation Therapy in Patients with Newly Diagnosed Glioblastoma
Participants currently recruited/enrolled
18-125 Years
NCI
Brain
20-C-0023
First-in-Human Phase I Trial to Investigate the Safety, Tolerability, Pharmacokinetics, Biological and Clinical Activity of Metarrestin (ML-246) in Subjects with Metastatic Solid Tumors
Participants currently recruited/enrolled
12-125 Years
NCI
Brain
20-AG-0087
Ketone ester effects on biomarkers of brain metabolism and cognitive performance in cognitively intact adults (Bullet) 55 years old. A double-blinded randomized controlled clinical trial
Participants currently recruited/enrolled
55-125 Years
NIA
Brain
20-AA-0057
The Effect of Acute Alcohol Intoxication on Neural Processes During Decisions to Engage in HIV Risk Behaviors
Participants currently recruited/enrolled
21-65 Years
NIAAA
Brain
19-NR-0098
Patient-Centered Assessment of Symptoms and Outcomes
Participants currently recruited/enrolled
18-125 Years
NINR
Brain
19-N-0124
Anakinra for the Treatment of Chronically Inflamed White Matter Lesions in Multiple Sclerosis
Participants currently recruited/enrolled
18-120 Years
NINDS
Brain
19-N-0114
Modulating the Hippocampal and Striatal Memory Networks with rTMS
Completed Study; data analyses ongoing
18-40 Years
NINDS
Brain
19-N-0081
A Traveling Subject Study of Replicability in Conventional and Advanced MRI MS Biomarkers
Completed Study; data analyses ongoing
18-125 Years
NINDS
Brain
19-N-0036
Exploring the Relationship Between Brain Asymmetry and Attention
Completed Study; data analyses ongoing
18-35 Years
NINDS
Brain
19-M-0107
The Mechanism of Action Underlying Ketamine's Antidepressant Effects: An Investigation of the AMPA Throughput Theory in Patients with Treatment-Resistant Major Depression
Participants currently recruited/enrolled
18-70 Years
NIMH
Brain
19-M-0095
PET Imaging of Neuroinflammation in Neurodegenerative Diseases via a Novel TSPO Radioligand
Participants currently recruited/enrolled
18-125 Years
NIMH
Brain
19-M-0073
Safety and Feasibility of Individualized Low Amplitude Seizure Therapy (iLAST)
Participants currently recruited/enrolled
22-70 Years
NIMH
Brain
19-I-0015
Phase 1/2 Randomized, Double-Blind, Placebo-Controlled Study of Safety and Efficacy of Abatacept for Treating Chronic Cytopenia in Cytotoxic T-lymphocyte Antigen 4 (CTLA4) Haploinsufficiency
Participants currently recruited/enrolled
8-65 Years
NIAID
Brain
19-HG-0101
A Phase 1/2 Study of Intravenous Gene Transfer with an AAV9 Vector Expressing Human Beta-galactosidase in Type I and Type II GM1 Gangliosidosis
No longer recruiting/follow-up only
0-12 Years
NHGRI
Brain
19-C-0103
A Study of Temozolomide, Etoposide, Doxil, Dexamethasone, Ibrutinib, and Rituximab (TEDDI-R) in Aggressive B-cell Lymphomas with Secondary Involvement of the Central Nervous System (CNS)
Participants currently recruited/enrolled
18-125 Years
NCI
Brain
19-C-0096
Studying the Biology of IDH-mutant Gliomas via Longitudinal Observation of 2-Hydroxyglutarate (2-HG) Using MR Spectroscopy
Participants currently recruited/enrolled
18-125 Years
NCI
Brain
19-C-0006
Phase II Trial Evaluating Nivolumab In Patients With IDH-Mutant Gliomas With And Without Hypermutator Phenotype
Participants currently recruited/enrolled
18-125 Years
NCI
Brain
18-N-0133
Feasibility of Endosphenoidal Coil Placement for Imaging of the Sella During Transsphenoidal Surgery
Participants currently recruited/enrolled
18-125 Years
NINDS
Brain
18-N-0077
Cytokine Microdialysis For Real Time Immune Monitoring in Glioblastoma Patients Undergoing Checkpoint Blockade
Completed Study; data analyses ongoing
18-125 Years
NINDS
Brain
18-N-0066
Investigating Epilepsy: Screening and Evaluation
Participants currently recruited/enrolled
8-125 Years
NINDS
Brain
18-N-0020
The Natural History of Blood-Brain Barrier Disruption in Stroke Patients with White Matter Hyperintensities (A Cohort Study)
No longer recruiting/follow-up only
18-125 Years
NINDS
Brain
18-M-0144
The effects of an ER beta agonist (Lilly Compound LY500307) on estradiol-withdrawal-induced mood symptoms in women with past perimenopausal depression.
Participants currently recruited/enrolled
45-65 Years
NIMH
Brain
18-M-0037
Characterization and Treatment of Adolescent Depression
Participants currently recruited/enrolled
11-25 Years
NIMH
Brain
18-M-0015
Development of Non-Invasive Brain Stimulation Techniques
Participants currently recruited/enrolled
18-65 Years
NIMH
Brain
18-H-0118
Technical and Translational Development of Cardiovascular MRI (CMR)
Participants currently recruited/enrolled
7-125 Years
NHLBI
Brain
18-EI-0046
Perception, Sensation, Cognition and Action in Humans
Participants currently recruited/enrolled
18-65 Years
NEI
Brain
18-DK-0132
Brain Dopamine Function in Human Obesity
No longer recruiting/follow-up only
18-125 Years
NIDDK
Brain
18-CH-0002
Investigations of Juvenile Neuronal Ceroid Lipofuscinosis (CLN3)
Participants currently recruited/enrolled
0-125 Years
NICHD
Brain
18-CH-0001
Mirror Neuron Network Dysfunction as an Early Biomarker of Neurodevelopmental Disorder
Participants currently recruited/enrolled
0-65 Years
NICHD
Brain
18-CC-0117
PET Imaging of the Dopaminergic and Serotonergic Systems in Treated HIV Positive Subjects
Completed Study; data analyses ongoing
18-70 Years
CC
Brain
18-CC-0052
Near-infrared Spectroscopy and Electroencephalography to Assess Cortical Activation During Motor Tasks in Infants and Toddlers with or at high-risk for Cerebral Palsy and Autism Spectrum Disorder Compared to Infants and Toddlers with Typical Development
Participants currently recruited/enrolled
0-5 Years
CC
Brain
18-C-0125
A Phase I Clinical Trial of T cells Expressing a Novel Fully-human Anti-BCMA CAR for Treating Multiple Myeloma
No longer recruiting/follow-up only
18-73 Years
NCI
Brain
18-C-0110
Safety Run-In and Phase II Trial of M7824 and Topotecan or Temozolomide in Relapsed Small Cell Cancers
Participants currently recruited/enrolled
18-125 Years
NCI
Brain
18-C-0080
Feasibility and Preliminary Efficacy of an Enhanced Mindfulness Intervention for Children and Young Adults with High Grade or High-Risk Cancer and Their Caregivers: A Pilot Randomized Controlled Trial
Completed Study; data analyses ongoing
5-125 Years
NCI
Brain
18-AA-0098
Investigating a Response Modulation Hypothesis of Socioemotional Processing associated with Alcohol Use Disorder
Participants currently recruited/enrolled
21-65 Years
NIAAA
Brain
17-N-0168
Influence of Brain Oscillation-Dependent TMS on Motor Function
Participants currently recruited/enrolled
18-125 Years
NINDS
Brain
17-N-0145
PD-1 Inhibition to Determine CNS Reservoir of HIV-Infection
Completed Study; data analyses ongoing
18-120 Years
NINDS
Brain
17-N-0055
Functional Connectivity as a Biomarker of rTMS
Completed Study; data analyses ongoing
18-125 Years
NINDS
Brain
17-N-0035
Clinical and Physiological Studies of Tremor Syndromes
Completed Study; data analyses ongoing
18-125 Years
NINDS
Brain
17-N-0031
Detailed Evaluation of the Neurophysiology of Surround Inhibition in the Human Motor Cortex
Completed Study; data analyses ongoing
18-70 Years
NINDS
Brain
17-M-0181
Recruitment and Characterization of Healthy Research Volunteers for NIMH Intramural Studies
Participants currently recruited/enrolled
18-125 Years
NIMH
Brain
17-M-0179
Evaluation of a Novel PET Radioligand to Image Cyclooxygenase-1 (COX-1)
Participants currently recruited/enrolled
18-99 Years
NIMH
Brain
17-M-0147
Concurrent fMRI-guided rTMS and Cognitive Therapy for the Treatment of Major Depressive Episodes
Participants currently recruited/enrolled
18-65 Years
NIMH
Brain
17-M-0060
Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive Disorder
Participants currently recruited/enrolled
18-65 Years
NIMH
Brain
17-I-0083
Targeting Residual Activity By Precision, Biomarker-Guided Combination Therapies of Multiple Sclerosis (TRAP-MS)
Participants currently recruited/enrolled
18-125 Years
NIAID
Brain
17-DA-0093
Exploring Gut-Brain and Brain-Gut Interactions in Alcohol Use Disorder via Microbiota Investigations: A Pilot Study
Completed Study; data analyses ongoing
21-70 Years
NIDA
Brain
17-CH-0020
Observational Study of Males with Creatine Transporter Deficiency (CTD)
No longer recruiting/follow-up only
2-40 Years
NICHD
Brain
17-CH-0014
Pilot Study of Mobile Attention Training in Overweight Female Adolescents
Participants currently recruited/enrolled
12-21 Years
NICHD
Brain
17-C-0175
CC-4047-BRN-001: A Phase 2 Clinical Study of Pomalidomide (CC-4047) Monotherapy for Children and Young Adults with Recurrent or Progressive Primary Brain Tumors
Completed Study; data analyses ongoing
3-20 Years
NCI
Brain
17-C-0125
Phase 2 Trial of Nivolumab in Epstein-Barr Virus (EBV)-Positive Lymphoproliferative Disorders and EBV-Positive Non-Hodgkin Lymphomas
Participants currently recruited/enrolled
12-125 Years
NCI
Brain
17-C-0115
Phase I/II Study of T-DM1 Alone Versus T-DM1 and Metronomic Temozolomide in Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases Following Stereotactic Radiosurgery
No longer recruiting/follow-up only
18-125 Years
NCI
Brain
17-C-0102
Phase II Trial of the Immune Checkpoint Inhibitor Nivolumab in Patients with Recurrent Select Rare CNS Cancers
Participants currently recruited/enrolled
18-99 Years
NCI
Brain
17-C-0037
Phase II Trial of LB100, a Protein Phosphatase 2A Inhibitor, in Recurrent Glioblastoma
Participants currently recruited/enrolled
18-125 Years
NCI
Brain
17-C-0034
A Randomized, Double Blind Phase II Trial of Surgery, Radiation Therapy Plus Temozolomide and Pembrolizumab with and without HSPPC-96 in Newly Diagnosed Glioblastoma (GBM)
Completed Study; data analyses ongoing
18-125 Years
NCI
Brain
17-C-0009
Phase I Trial of Zotiraciclib (TG02) Plus Dose-Dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of Zotiraciclib (TG02) plus Temozolomide versus Temozolomide alone in Adults with Recurrent Anaplastic Astrocytoma and Glioblastoma
Completed Study; data analyses ongoing
18-125 Years
NCI
Brain
17-AT-0075
Sensory and Opioid Mechanisms of Affective Touch
Completed Study; data analyses ongoing
18-50 Years
NCCIH
Brain
17-AA-0178
Dopaminergic Modulation of Brain Activation Using Simultaneous PET/Pharmacological MRI
Enrolling by Invitation
18-55 Years
NIAAA
Brain
17-AA-0171
Nicotinic Receptor Genetic Variation and Alcohol Reward
Participants currently recruited/enrolled
21-60 Years
NIAAA
Brain
17-AA-0114
Brain Dopaminergic Signaling in Opioid use Disorders (OUD)
Participants currently recruited/enrolled
18-80 Years
NIAAA
Brain
16-N-0170
Effects of Prism Adaption and rTMS on Brain Connectivity and Visual Representation
Completed Study; data analyses ongoing
18-75 Years
NINDS
Brain
16-N-0166
Deep Brain Stimulation Surgery for Treatment of Focal Hand Dystonia
Participants currently recruited/enrolled
22-125 Years
NINDS
Brain
16-N-0114
The Effect of Corticosteroids on Inflammation at the Edge of Acute Multiple Sclerosis Plaques: An Investigator-Blinded Study
Participants currently recruited/enrolled
18-125 Years
NINDS
Brain
16-N-0072
A Pilot Study of Adoptive Cellular Immunotherapy for Progressive Multifocal Leukoencephalopathy with Ex Vivo Generated Polyomavirus-Specific T-cells
Completed Study; data analyses ongoing
18-125 Years
NINDS
Brain
16-N-0064
Cholinergic Receptor Imaging in Dystonia
Completed Study; data analyses ongoing
18-125 Years
NINDS
Brain
16-N-0058
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Completed Study; data analyses ongoing
18-60 Years
NINDS
Brain
16-N-0055
The Pathological Basis of MRI Signal Changes in Multiple Sclerosis: A Longitudinal In Vivo-to-Postmortem Study
Participants currently recruited/enrolled
18-125 Years
NINDS
Brain
16-N-0041
Tumor Related Epilepsy
Participants currently recruited/enrolled
8-125 Years
NINDS
Brain
16-N-0031
An All-Night Functional Magnetic Resonance Imaging Sleep Study With Auditory Stimuli
Participants currently recruited/enrolled
18-34 Years
NINDS
Brain
16-HG-0156
The Natural History, Physiology, Microbiome and Biochemistry Studies of Propionic Acidemia
Participants currently recruited/enrolled
0-125 Years
NHGRI
Brain
16-H-0144
Impact of Elastin Mediated Vascular Stiffness on End Organs
Participants currently recruited/enrolled
3-85 Years
NHLBI
Brain
16-H-0132
CADASIL Disease Discovery
Completed Study; data analyses ongoing
18-100 Years
NHLBI
Brain
16-EI-0090
Natural History of Spinocerebellar Ataxia Type 7 (SCA7)
Participants currently recruited/enrolled
12-125 Years
NEI
Brain
16-CC-0149
Dopamine and Motor Learning in Cerebral Palsy
Participants currently recruited/enrolled
5-25 Years
CC
Brain
16-C-0151
Evaluation of the Natural History of and Specimen Banking for Patients with Tumors of the Central Nervous System
Participants currently recruited/enrolled
18-125 Years
NCI
Brain
16-C-0097
Phase 1 Trial of Panobinostat in Children with Diffuse Intrinsic Pontine Glioma
Completed Study; data analyses ongoing
2-21 Years
NCI
Brain
16-C-0081
A Phase I Dose Escalation Trial of Re-Irradiation in Good Prognosis Recurrent Glioblastoma
No longer recruiting/follow-up only
18-125 Years
NCI
Brain
16-C-0034
A Phase II Trial of Oral Pazopanib plus Oral Topotecan Metronomic Antiangiogenic Therapy for Recurrent Glioblastoma Multiforme (A) without Prior Bevacizumab Exposure and (B) after Failing Prior Bevacizumab
Completed Study; data analyses ongoing
18-125 Years
NCI
Brain
16-C-0011
A Phase I-II Trial of Everolimus and Sorafenib in Patients with Recurrent High-Grade Gliomas
Completed Study; data analyses ongoing
18-125 Years
NCI
Brain
16-C-0009
Phase II Trial of Carboplatin and Bevacizumab for the Treatment of Recurrent Low-Grade and Anaplastic Supratentorial, Infratentorial and Spinal Cord Ependymoma in Adults: A Multi-Center Trial
Completed Study; data analyses ongoing
18-125 Years
NCI
Brain
16-AT-0136
Effects of External Ear Stimulation on Pain Perception and Mood
Participants currently recruited/enrolled
18-50 Years
NCCIH
Brain
16-AA-0059
Characterization of Brain Amyloid-beta (A-beta) Retention During Wakefulness And Following Emergence From Sleep In Healthy Subjects
Completed Study; data analyses ongoing
18-40 Years
NIAAA
Brain
16-AA-0037
Effect of Opioid Receptor Modulation on Alcohol Self-Administration and Neural Response to Alcohol Cues in Heavy Drinkers: Role of OPRM1 Gene Variation
Participants currently recruited/enrolled
21-60 Years
NIAAA
Brain
15-N-0177
Investigation of Blood-Brain-Barrier Breakdown Using Manganese Magnetic Resonance Imaging in Drug-Resistant Epilepsy
Recruitment has not started
18-60 Years
NINDS
Brain
15-N-0167
Propensity to develop plasticity in the parieto-motor network in dystonia from the perspective of abnormal high-order motor processing
Completed Study; data analyses ongoing
18-65 Years
NINDS
Brain
15-N-0125
Natural History Study of Inflammatory and Infectious Diseases of the Nervous System
Participants currently recruited/enrolled
2-125 Years
NINDS
Brain
15-N-0081
A Study of Direct Brain Recording and Stimulation for Memory Enhancement
Enrolling by Invitation
18-65 Years
NINDS
Brain
15-N-0073
A Phase I Study of Intrathecal Administration of scAAV9/JeT-GAN for the Treatment of Giant Axonal Neuropathy
Participants currently recruited/enrolled
3-99 Years
NINDS
Brain
15-M-0188
The Neurobiology of Suicide
Participants currently recruited/enrolled
18-70 Years
NIMH
Brain
15-M-0151
An Investigation of the Antidepressant Effects of the Glycine Receptor Antagonist AV 101 (4-chlorokynurenine) in Major Depressive Disorder
Completed Study; data analyses ongoing
18-65 Years
NIMH
Brain
15-M-0139
Mapping the Genotype, Phenotype, and Natural History of Phelan McDermid Syndrome
Participants currently recruited/enrolled
1-125 Years
NIMH
Brain
15-M-0066
Influence on Plasticity of Brain Temperature
Participants currently recruited/enrolled
18-50 Years
NIMH
Brain
15-CH-0096
Children's Growth and Behavior Study
Participants currently recruited/enrolled
8-125 Years
NICHD
Brain
15-CC-0164
Effect of Exercise Training on Physical, Cognitive and Behavioral Function in Patients with Traumatic Brain Injury
Completed Study; data analyses ongoing
18-79 Years
CC
Brain
15-C-0138
Phase I Study of Ipilimumab, Nivolumab, and the Combination in Patients with Newly Diagnosed Glioblastoma
Completed Study; data analyses ongoing
18-125 Years
NCI
Brain
15-AT-0132
Neural and Psychological Mechanisms of Pain Perception
Participants currently recruited/enrolled
18-50 Years
NCCIH
Brain
15-AG-0123
Intermittent Calorie Restriction, Insulin Resistance, and Biomarkers of Brain Function
Completed Study; data analyses ongoing
55-70 Years
NIA
Brain
15-AA-0203
Cross-Sectional and Longitudinal Study of Structural Imaging
Completed Study; data analyses ongoing
30-60 Years
NIAAA
Brain
15-AA-0186
Development of Neuroimaging Methods to Assess the Neurobiology of Addiction
Participants currently recruited/enrolled
18-125 Years
NIAAA
Brain
15-AA-0031
Human Brain Mapping of the Apparent Diffusion Coefficient (ADC) during Sleep and Wakefulness
Completed Study; data analyses ongoing
18-60 Years
NIAAA
Brain
14-N-0086
Deep Brain Stimulation Therapy in Movement Disorders
Participants currently recruited/enrolled
18-125 Years
NINDS
Brain
14-N-0083
Neural Basis of Decision Making Deficits in Traumatic Brain Injury
Participants currently recruited/enrolled
18-60 Years
NINDS
Brain
14-HG-0071
Clinical and Basic Investigations into Known and Suspected Congenital Disorders of Glycosylation
Participants currently recruited/enrolled
1-80 Years
NHGRI
Brain
14-HG-0055
Study on Moebius Syndrome and Other Congenital Facial Weakness Disorders
Completed Study; data analyses ongoing
2-80 Years
NHGRI
Brain
14-H-0155
A Phase 1/2 Study Evaluating Gene Therapy by Transplantation of Autologous CD34+ Stem Cells Transduced Ex Vivo with the LentiGlobin BB305 Lentiviral Vector in Subjects with Severe Sickle Cell Disease
No longer recruiting/follow-up only
18-50 Years
NHLBI
Brain
14-C-0157
Phase 1 Study of Ibrutinib and Immuno-Chemotherapy Using Temozolomide, Etoposide, Doxil, Dexamethasone, Ibrutinib, Rituximab (TEDDI-R) in Primary CNS Lymphoma
Participants currently recruited/enrolled
18-125 Years
NCI
Brain
14-C-0116
A Randomized Controlled Trial Evaluating an Enhanced Physical Activity Intervention to Improve Cognitive Late Effects in Children Treated with Cranial Radiation for Brain Tumors
Participants currently recruited/enrolled
8-125 Years
NCI
Brain
14-C-0037
A Phase 2 Study of the MET Kinase Inhibitor INC280 in Papillary Renal Cell Cancer
Completed Study; data analyses ongoing
18-125 Years
NCI
Brain
14-AA-0192
Brain Inflammation and Function in Alcoholism
Completed Study; data analyses ongoing
30-75 Years
NIAAA
Brain
14-AA-0187
Dopamine Rhythms in Health and Addiction
Clinical hold/Recruitment or enrollment suspended
21-55 Years
NIAAA
Brain
14-AA-0181
NIAAA Natural History Protocol
Participants currently recruited/enrolled
18-100 Years
NIAAA
Brain
14-AA-0144
Reliability Of The Human Brain Connectome
Participants currently recruited/enrolled
18-125 Years
NIAAA
Brain
14-AA-0080
Characterization Imaging Instruments for Addiction Neuroimaging Assessments
Participants currently recruited/enrolled
18-125 Years
NIAAA
Brain
14-AA-0066
Behavioral and Functional Task Development, Implementation, and Testing
Participants currently recruited/enrolled
18-65 Years
NIAAA
Brain
13-N-0188
Natural History and Biomarkers of C9ORF72 Amyotrophic Lateral Sclerosis and Frontotemporal Dementia
Completed Study; data analyses ongoing
18-125 Years
NINDS
Brain
13-N-0149
An Evaluation of HIV-associated Neurocognitive Disorders (HAND) in Virologically Controlled Patients
Participants currently recruited/enrolled
18-125 Years
NINDS
Brain
13-N-0140
Cerebrospinal Fluid Collection and Repository Storage
Participants currently recruited/enrolled
2-125 Years
NINDS
Brain
13-N-0017
Natural History Study of Progressive Multifocal Leukoencephalopathy (PML)
Participants currently recruited/enrolled
2-125 Years
NINDS
Brain
13-M-0028
Diagnosis of Childhood-onset Behavioral Disorders, Neuropsychiatric Disorders and Neurodevelopmental Disorders
Participants currently recruited/enrolled
0-99 Years
NIMH
Brain
13-CC-0210
Evaluating an Extension Assist Knee Ankle Foot Orthosis to Improve Gait in Children with Movement Disorders
Participants currently recruited/enrolled
5-125 Years
CC
Brain
13-CC-0110
Near-infrared Spectroscopy and Electroencephalography to Assess and Train Cortical Activation During Motor Tasks
Participants currently recruited/enrolled
5-125 Years
CC
Brain
13-C-0152
A Phase I Study of Autologous Activated Natural Killer (NK) Cells +/- rhIL15 in Children and Young Adults with Refractory Solid Tumors
Completed Study; data analyses ongoing
2-29 Years
NCI
Brain
13-AG-0034
Phase I, Double-Blind, Placebo-Controlled, Ascending, Single-Dose, Safety, Tolerability and Pharmacokinetic Study of Bisnorcymserine (BNC), a Highly Selective Inhibitor of Butyrylcholinesterase, in Healthy Adult Volunteers
Completed Study; data analyses ongoing
55-125 Years
NIA
Brain
12-N-0137
A Phase 1 Open-Label Dose Escalation Safety Study of Convection Enhanced Delivery (CED) of Adeno-Associated Virus Encoding Glial Cell Line-Derived Neurotrophic Factor (AAV2-GDNF) in Subjects with Advanced Parkinson's Disease.
Completed Study; data analyses ongoing
18-125 Years
NINDS
Brain
12-N-0031
Imaging Biomarkers in Parkinson Disease
Completed Study; data analyses ongoing
18-100 Years
NINDS
Brain
12-M-0128
TMS Investigations of the Human Visual System
Participants currently recruited/enrolled
18-50 Years
NIMH
Brain
12-HG-0202
The Neurobehavioral, Environmental and Genetic Factors Impacting the Clinical Course of Attention Deficit Hyperactivity Disorder
Participants currently recruited/enrolled
3-125 Years
NHGRI
Brain
12-E-0050
The Role of Gonadotropin Pulsations in the Regulation of Puberty and Fertility
Participants currently recruited/enrolled
14-125 Years
NIEHS
Brain
12-DC-0152
Normative Values in Audiovestibular Testing
Participants currently recruited/enrolled
5-80 Years
NIDCD
Brain
12-CC-0139
Estimation of Brain Biomechanics using MRI
Participants currently recruited/enrolled
18-65 Years
CC
Brain
11-N-0211
Deep Brain Stimulation Surgery for Movement Disorders
Participants currently recruited/enrolled
18-125 Years
NINDS
Brain
11-N-0084
Evaluation and Diagnosis of Potential Research Subjects with Traumatic Brain Injury (TBI)
Completed Study; data analyses ongoing
18-125 Years
NINDS
Brain
11-N-0051
Surgery as a Treatment for Medically Intractable Epilepsy
Participants currently recruited/enrolled
8-125 Years
NINDS
Brain
11-M-0251
A Longitudinal Investigation of the Endocrine and Neurobiologic Events Accompanying Puberty
Participants currently recruited/enrolled
7-35 Years
NIMH
Brain
11-M-0045
Development of Magnetic Resonance Spectroscopic Imaging Techniques for Imaging Metabolites in Human Brain and Muscle
Participants currently recruited/enrolled
18-65 Years
NIMH
Brain
11-CC-0088
Effect of Aerobic Exercise Training on Cardiorespiratory Fitness in Patients with Traumatic Brain Injury
Completed Study; data analyses ongoing
21-45 Years
CC
Brain
11-C-0255
Clinical, Epidemiologic, and Genetic Studies of Li-Fraumeni Syndrome
Participants currently recruited/enrolled
0-125 Years
NCI
Brain
11-C-0161
A Phase I/II Study of the Mitogen Activated Protein Kinase Kinase (MEK) 1 Inhibitor Selumetinib (AZD6244; Hydrogen Sulfate in Children with Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas (PN)
No longer recruiting/follow-up only
2-18 Years
NCI
Brain
10-N-0122
Evaluation, Pathogenesis, and Outcome of Subjects with or Suspected Traumatic Brain Injury
Completed Study; data analyses ongoing
18-125 Years
NINDS
Brain
10-N-0012
Screening Protocol for Patients with Stroke
Participants currently recruited/enrolled
18-90 Years
NINDS
Brain
10-N-0009
Physiological Investigations of Movement Disorders
Completed Study; data analyses ongoing
18-125 Years
NINDS
Brain
10-M-0112
Defining the Brain Phenotype of Children with Williams Syndrome
Participants currently recruited/enrolled
5-125 Years
NIMH
Brain
10-M-0047
Top-Down Attentional Control of Visual-Processing
Participants currently recruited/enrolled
18-125 Years
NIMH
Brain
10-M-0027
Cognitive Neuroscience of Autism Spectrum Disorders
Participants currently recruited/enrolled
5-89 Years
NIMH
Brain
10-CC-0150
Effects of Rapid-Resisted Exercise on Ambulatory Adults with Traumatic Brain Injury
Completed Study; data analyses ongoing
18-44 Years
CC
Brain
10-CC-0118
Long Term Clinical Correlates of TBI: Imaging, Biomarkers, and Clinical Phenotyping Parameters
Participants currently recruited/enrolled
18-125 Years
CC
Brain
10-AG-0423
A Pilot Study of Exendin-4 in Alzheimer's Disease
Completed Study; data analyses ongoing
60-125 Years
NIA
Brain
09-M-0176
Functional Relevance of Dopamine Receptors in Healthy Controls and Patients with Schizophrenia: Characterization through [11C]NNC-112 and [18F]Fallypride Positron Emission Tomography
Participants currently recruited/enrolled
18-90 Years
NIMH
Brain
09-I-0032
Comprehensive Multimodal Analysis of Patients with Neuroimmunological Diseases of the CNS
Participants currently recruited/enrolled
0-99 Years
NIAID
Brain
09-DK-0081
Selective Reduction of Dietary Carbohydrate Versus Fat: Effects on Metabolism, Endocrine Physiology, Brain Activity and Reward Circuitry
Completed Study; data analyses ongoing
18-45 Years
NIDDK
Brain
08-N-0044
A Prospective Natural History Study of Patients with Neurofibromatosis Type 2 (NF2).
Participants currently recruited/enrolled
8-75 Years
NINDS
Brain
08-EI-0031
Visual Motor Coordination
Participants currently recruited/enrolled
18-125 Years
NEI
Brain
08-C-0214
A Pilot Study to Evaluate Neuropsychological Outcome Measures and their Relationship with Prognosis in Patients Receiving Radiation Therapy for Brain Metastases
Participants currently recruited/enrolled
18-125 Years
NCI
Brain
08-C-0079
Natural History Study and Longitudinal Assessment of Children, Adolescents, and Adults with Neurofibromatosis Type 1
No longer recruiting/follow-up only
0-125 Years
NCI
Brain
08-AG-0238
Development of 3T Magnetic Resonance Research Methods for NIA Studies
Participants currently recruited/enrolled
18-125 Years
NIA
Brain
07-N-0190
Neurobiological Studies of Functional Movement Disorders and Non-Epileptic Seizures
No longer recruiting/follow-up only
18-125 Years
NINDS
Brain
07-N-0122
Modulation of Motor Function by Stimulation of the Central and Peripheral Nervous System
Completed Study; data analyses ongoing
18-125 Years
NINDS
Brain
07-M-0021
Development of Functional and Structural Magnetic Resonance Imaging Techniques for the Study of Mood and Anxiety Disorders
Participants currently recruited/enrolled
18-65 Years
NIMH
Brain
07-C-0110
Analysis of Stored Data Collected from Individuals Administered Neurobehavioral Assessments on IRB-Approved Protocols
Enrolling by Invitation
0-125 Years
NCI
Brain
06-M-0214
PET Measurement of Regional Rates of Cerebral Protein Synthesis in Subjects with Fragile X Syndrome
Completed Study; data analyses ongoing
18-24 Years
NIMH
Brain
06-HG-0055
Functional Imaging in Subjects with Glucocerebrosidase Mutations
Completed Study; data analyses ongoing
18-125 Years
NHGRI
Brain
06-CH-0186
Evaluation of Biochemical Markers and Clinical Investigation of Niemann-Pick Disease, Type C
Participants currently recruited/enrolled
0-125 Years
NICHD
Brain
06-C-0219
An Exploratory Study of Biologic and Pathophysiologic Effects of Radiation Therapy in Pediatric Patients with Central Nervous System Tumors
Completed Study; data analyses ongoing
0-21 Years
NCI
Brain
05-M-0144
MRS (Magnetic Resonance Spectroscopy) Measurement of Glutamate and GABA Metabolism in Brain
Participants currently recruited/enrolled
18-65 Years
NIMH
Brain
05-H-0130
Long-Term Evaluation and Follow Up Care of Patients Treated with Allogeneic Stem Cell Transplants
Participants currently recruited/enrolled
7-80 Years
NHLBI
Brain
04-C-0238
A Phase 2 Study of 17-Allylamino-17-Demethoxygeldanamycin in Patients with Von Hippel Lindau Disease and Renal Tumors
Completed Study; data analyses ongoing
18-125 Years
NCI
Brain
04-C-0200
Urinary and Serum VEGF and MMP Levels in Patients Receiving Radiation Therapy for Glioblastoma Multiforme: Prospective Determination of a Predictive Value for Recurrence
Participants currently recruited/enrolled
18-125 Years
NCI
Brain
03-N-0164
Evaluation and Treatment of Neurosurgical Disorders
Participants currently recruited/enrolled
4-125 Years
NINDS
Brain
03-M-0186
The Psychobiology of Temperament: An fMRI Study
Participants currently recruited/enrolled
0-30 Years
NIMH
Brain
03-H-0282
Characterization of Cardiac Function in Subjects with Hereditary Hemochromatosis Who Are New York Heart Association Functional Class I
Completed Study; data analyses ongoing
21-100 Years
NHLBI
Iron
03-C-0278
A Comparative Study of Pediatric CNS Tumor Activity as Assessed by 18F-FDG PET Imaging and Proton Magnetic Resonance Spectroscopic Imaging (1H-MRSI)
Completed Study; data analyses ongoing
1-21 Years
NCI
Brain
03-AG-0325
The Baltimore Longitudinal Study of Aging(BLSA)
Participants currently recruited/enrolled
20-125 Years
NIA
Brain
02-N-0014
Research Study of Specimens Obtained During Epilepsy Surgery
Completed Study; data analyses ongoing
4-125 Years
NINDS
Brain
02-M-0321
fMRI Investigation of Explicit Cue and Contextual Fear
Completed Study; data analyses ongoing
18-50 Years
NIMH
Brain
02-M-0021
Characterization and Pathophysiology of Severe Mood and Behavioral Dysregulation in Children and Youth
Participants currently recruited/enrolled
7-60 Years
NIMH
Brain
02-DK-0022
Long-Term Efficacy of Leptin Replacement in Treatment of Lipodystrophy
Completed Study; data analyses ongoing
1-125 Years
NIDDK
Accumulation
02-C-0313
Cancer Risk in Xeroderma Pigmentosum Heterozygotes
Participants currently recruited/enrolled
0-99 Years
NCI
Brain
01-N-0007
Evaluation, Pathogenesis, and Treatment of Patients with or at Risk for Cerebrovascular Disease (A Natural History/Disease Pathogenesis Protocol)
Participants currently recruited/enrolled
18-125 Years
NINDS
Brain
01-M-0254
The Evaluation of Patients with Mood and Anxiety Disorders and Healthy Volunteers
Participants currently recruited/enrolled
3-99 Years
NIMH
Brain
01-M-0192
Fluoxetine's Effects on Attention and Emotional Memory in Anxious and Depressed Youth and Adults
Participants currently recruited/enrolled
8-65 Years
NIMH
Brain
01-CC-0045
Studies of Phlebotomy Therapy in Hereditary Hemochromatosis
Participants currently recruited/enrolled
18-125 Years
CC
Iron
00-N-0140
A Prospective Natural History Study of VHL Patients with CNS Hemangioblastomas
No longer recruiting/follow-up only
8-75 Years
NINDS
Brain
00-N-0089
Genetic Analysis of the Chiari I Malformation
Completed Study; data analyses ongoing
1-125 Years
NINDS
Brain
00-N-0082
Characterization of Brain Morphology and Activity Using Functional and Anatomical MRI Contrast
Participants currently recruited/enrolled
18-125 Years
NINDS
Brain
00-N-0043
Clinical and Molecular Manifestations of Inherited Neurological Disorders
Participants currently recruited/enrolled
2-125 Years
NINDS
Brain
00-M-0198
The Phenomenology and Neurophysiology of Affective Dysregulation in Children and Adolescents with Bipolar Disorder
Completed Study; data analyses ongoing
3-58 Years
NIMH
Brain
00-M-0085
Structural and Functional Imaging of Neuropsychiatric Patients and Normal Volunteers with 3.0 Tesla MRI and Magnetoencephalography (MEG)
Participants currently recruited/enrolled
18-125 Years
NIMH
Brain
00-HG-0141
Clinical, Biochemical, and Molecular Investigations into Alkaptonuria
Participants currently recruited/enrolled
2-125 Years
NHGRI
Brain
00-CH-0160
Clinical and Molecular Analysis of ACTH-Independent Steroid Hormone Production in Adrenocortical Tissue
Completed Study; data analyses ongoing
3-70 Years
NICHD
Brain
98-CH-0081
Clinical and Basic Investigations into Smith-Lemli-Opitz Syndrome
Completed Study; data analyses ongoing
0-125 Years
NICHD
Brain
97-HG-0192
Genetic Studies in the Amish and Mennonites
Completed Study; data analyses ongoing
18-125 Years
NHGRI
Brain
96-I-0052
A Comprehensive Clinical, Microbiological and Immunological Assessment of Patients with Suspected Post Treatment Lyme Disease Syndrome and Selected Control Populations
Participants currently recruited/enrolled
13-125 Years
NIAID
Brain
95-M-0150
A Neurobiological Investigation of Patients with Schizophrenia Spectrum Disorders and Their Siblings
Participants currently recruited/enrolled
18-55 Years
NIMH
Brain
95-HG-0193
Clinical and Basic Investigations into Hermansky-Pudlak Syndrome
Participants currently recruited/enrolled
0-125 Years
NHGRI
Accumulation
94-I-0079
Eosinophil Activation and Function in Parasitic Infections and Other Conditions with Increased Tissue or Peripheral Blood Eosinophilia in Humans
Participants currently recruited/enrolled
1-100 Years
NIAID
Accumulation
93-M-0170
Regional Cerebral Blood Flow Studies of Object Perception, Identification, Localization, and Memory
Participants currently recruited/enrolled
18-65 Years
NIMH
Brain
92-M-0174
The Central Nervous System Effects of Pharmacologically Induced Hypogonadotropic Hypogonadism with and without Estrogen and Progesterone Replacement
Completed Study; data analyses ongoing
18-50 Years
NIMH
Brain
90-M-0088
The Treatment of Menstrually-Related Mood Disorders with the Gonadotropin Releasing Hormone (GnRH) Agonist, Depot Leuprolide Acetate (Lupron)
Completed Study; data analyses ongoing
18-45 Years
NIMH
Brain
90-M-0014
Studies of Frontal Lobe Function During Cognitive Stimulation as Measured with Oxygen-15 Water Positron Emission Tomography in Normal Subjects and Patients with Neuropsychiatric Disorders
Completed Study; data analyses ongoing
18-90 Years
NIMH
Brain
89-N-0045
Evaluation of Progression in Multiple Sclerosis by Magnetic Resonance Imaging (MRI)
Participants currently recruited/enrolled
18-125 Years
NINDS
Brain
89-M-0160
Inpatient Evaluation of Neuropsychiatric Patients
Participants currently recruited/enrolled
18-125 Years
NIMH
Brain
89-M-0006
Brain Imaging of Childhood Onset Psychiatric Disorders, Endocrine Disorders and Healthy Volunteers
Participants currently recruited/enrolled
3-125 Years
NIMH
Brain
85-I-0127
Natural History of Treated Neurocysticercosis and Long-Term Outcomes
Participants currently recruited/enrolled
3-99 Years
NIAID
Brain
78-HG-0093
Use of Cysteamine in the Treatment of Cystinosis
Participants currently recruited/enrolled
0-125 Years
NHGRI
Accumulation