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66 Studies found from all possible combinations of your search terms. Select a protocol that you wish to review.
Protocol Number Title Protocol Status Min-Max Age Institute Keywords
18-D-0114An Open Label Pilot Study of Denosumab Treatment for Fibrous DysplasiaNo longer recruiting/follow-up only18-125 YearsNIDCRMineral Metabolism
001085-DPhase 2 Study of the PTH-Independent Effects of Encaleret on Mineral Homeostasis in Subjects with Post-Surgical Hypoparathyroidism (PSH)Recruitment has not started18-125 YearsNIDCRMineral
001058-DKA Phase 1b/2a Open-label Multiple-ascending Dose Exploratory Study of CRN04894 in ACTH-dependent Cushing's Syndrome (Cushing's Disease or Ectopic ACTH Syndrome)Recruitment has not started18-75 YearsNIDDKMetabolism
000957-HGA Phase 1/2, Open-Label, Single Dose Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of SEL-302 (MMA-101 following administration of SEL-110) in Pediatric Subjects with Mut Subtype Isolated Methylmalonic Acidemia (MMA)Participants currently recruited/enrolled3-17 YearsNHGRIMetabolism
000911-DKDinner Time for Obesity and Prediabetes (DTOP)Recruitment has not started18-50 YearsNIDDKMetabolism
000908-DKPeripheral Blood and Urine Immune Cell Phenotyping in Membranous Nephropathy using FACS and Single Cell RNA-seqParticipants currently recruited/enrolled18-125 YearsNIDDKMetabolism
000906-IA Phase 2 Randomized, Double-Blinded Cross-Over Design Study of the Early Metabolic Effects of Dolutegravir or Tenofovir Alefenamide in Healthy VolunteersRecruitment has not started18-55 YearsNIAIDMetabolism
000756-DKPhase II Study of Growth Hormone Inhibition Using Pegvisomant In Severe Insulin ResistanceParticipants currently recruited/enrolled18-65 YearsNIDDKMetabolism
000617-DKA Natural History Study of Metabolic Sizing in Health and DiseaseParticipants currently recruited/enrolled10-125 YearsNIDDKMetabolism
000487-CHNatural History Investigation into Biochemical and Phenotypical Aspects of Smith-Lemli-Opitz Syndrome and Related Disorders of Cholesterol MetabolismParticipants currently recruited/enrolled0-125 YearsNICHDMetabolism
000236-IA Phase 1 Study of Empagliflozin as Treatment for Severe Congenital Neutropenia Due to G6PC3 DeficiencyParticipants currently recruited/enrolled18-125 YearsNIAIDMetabolism
000235-CHCOLSIO Trial: Phase II Randomized, Controlled Trial of Colchicine to Suppress Inflammation and Improve Insulin Resistance in Adults and Adolescents with ObesityParticipants currently recruited/enrolled12-125 YearsNICHDMetabolism
000149-HPilot Study to Explore the Anti-Inflammatory Effects of Time-Restricted FeedingParticipants currently recruited/enrolled18-80 YearsNHLBIMetabolism
000043-DKDeveloping Biomarkers of Dietary Intake: Dose Dependent Measurement of Sugar IntakeParticipants currently recruited/enrolled18-65 YearsNIDDKMetabolism
22-DK-0002Effect of Ultra-processed versus Unprocessed Diets on Energy MetabolismParticipants currently recruited/enrolled18-60 YearsNIDDKMetabolism
20-M-0157PET Imaging of Cyclooxygenase in Participants with Major Depressive Disorder (MDD)Participants currently recruited/enrolled18-70 YearsNIMH Mineral
20-HG-0120Acute Infection in Mitochondrial Disease: An Observational Prospective Natural History Study of Metabolism, Infection and Immunity During the COVID19 PandemicParticipants currently recruited/enrolled0-125 YearsNHGRIMetabolism
20-C-0107Clinical, Genetic, and Epidemiologic Study of Children and Adults with RASopathiesParticipants currently recruited/enrolled0-125 YearsNCI Metabolism
20-AG-0087Ketone ester effects on biomarkers of brain metabolism and cognitive performance in cognitively intact adults (Bullet) 55 years old. A double-blinded randomized controlled clinical trialParticipants currently recruited/enrolled55-125 YearsNIA Metabolism
19-H-0139Investigation of the Natural Progression of Clonal Hematopoiesis of Indeterminate Potential and Clonal Cytopenia of Undetermined Significance.Participants currently recruited/enrolled18-125 YearsNHLBIMineral
19-H-0034Exploratory Study of Nicotinamide Riboside on Mitochondrial Function in Li-Fraumeni SyndromeCompleted Study; data analyses ongoing18-70 YearsNHLBIMetabolism
19-DK-0067Effect of Low Fat versus Low Carbohydrate Diets on Energy MetabolismCompleted Study; data analyses ongoing18-50 YearsNIDDKMetabolism
19-CH-0051Long-Term Follow-UP of Survivors of Pediatric Cushing DiseaseParticipants currently recruited/enrolled2-90 YearsNICHDMineral
19-CH-0020A Phase 1-2 Multi-Center Study to Assess the Efficacy and Safety of Abiraterone Acetate as Adjunctive Therapy in Pre-Pubescent Children with Classic 21-Hydroxylase DeficiencyRecruitment has not started2-9 YearsNICHDMetabolism
18-H-0019Effect of Dietary Omega-7 Palmitoleic Acid-Rich Oil on Lipoprotein Metabolism and Satiety in AdultsParticipants currently recruited/enrolled18-125 YearsNHLBIMetabolism
18-AA-0047Effects of Sucralose on Drug Absorption and Metabolism (The SweetMeds Study)Clinical hold/Recruitment or enrollment suspended18-60 YearsNIAAAMetabolism
17-DK-N004Energy Intake Response to Short-Term Alterations of Energy Expenditure in HumansParticipants currently recruited/enrolled18-55 YearsNIDDKMetabolism
17-DK-0054The Physiological Responses and Adaptation of Brown Adipose Tissue to Chronic Treatment with Beta3-Adrenergic Receptor AgonistsParticipants currently recruited/enrolled18-40 YearsNIDDKMetabolism
17-DA-0093Exploring Gut-Brain and Brain-Gut Interactions in Alcohol Use Disorder via Microbiota Investigations: A Pilot StudyCompleted Study; data analyses ongoing21-70 YearsNIDA Metabolism
17-CH-0130Break It Up: A Study Evaluating Breaking Up daily sedentary behavior in youthCompleted Study; data analyses ongoing7-11 YearsNICHDMetabolism
16-HG-0156The Natural History, Physiology, Microbiome and Biochemistry Studies of Propionic AcidemiaParticipants currently recruited/enrolled0-125 YearsNHGRIMetabolism
16-DK-0143Idiosyncratic Liver Injury Associated with Drugs (ILIAD): A Retrospective StudyParticipants currently recruited/enrolled18-125 YearsNIDDKMetabolism
16-DK-0068The Molecular, Cellular, and Genetic Characterization of Human Adipose Tissue and its Role in MetabolismParticipants currently recruited/enrolled18-125 YearsNIDDKMetabolism
16-DK-0038A Randomized, Double Blind, Placebo-Controlled Study to Assess Efficacy, Safety and Tolerability of ISIS 304801 in Patients with Partial Lipodystrophy with an Open-Label ExtensionCompleted Study; data analyses ongoing18-125 YearsNIDDKMetabolism
16-CH-0113Evaluation of Children with Endocrine and Metabolic-Related ConditionsParticipants currently recruited/enrolled0-100 YearsNICHDMetabolism
15-HG-0049Maternal Inborn Errors of Metabolism in Pregnancy: A Pregnancy Registry ProtocolCompleted Study; data analyses ongoing14-50 YearsNHGRIMetabolism
15-DK-0192Quantifying Weight Regain and the Persistence of Metabolic Adaptation Following Extreme Weight LossCompleted Study; data analyses ongoing18-125 YearsNIDDKMetabolism
15-DK-0174Dynamic Post-Prandial Metabolism in Patients with Non-Alcoholic Fatty Liver DiseaseCompleted Study; data analyses ongoing18-125 YearsNIDDKMetabolism
15-DK-0119Thyroid Hormone to Induce Non-Insulin Mediated Glucose Disposal in Patients with Insulin Receptor MutationsCompleted Study; data analyses ongoing12-65 YearsNIDDKMetabolism
14-DK-0195Acute Effects of Canagliflozin, a Sodium Glucose Co-Transporter 2 (SGLT2) Inhibitor on Bone Metabolism in Healthy VolunteersCompleted Study; data analyses ongoing18-125 YearsNIDDKMetabolism
14-C-0001Phase II Study of Axitinib (AG-013736) with Evaluation of the VEGF-pathway in Metastatic, Recurrent or Primary Unresectable Pheochromocytoma/ParagangliomaCompleted Study; data analyses ongoing18-125 YearsNCI Metabolism
13-HG-0053The NIH Mini Study: Metabolism, INfection and Immunity in Inborn Errors of Mitochondrial MetabolismParticipants currently recruited/enrolled2-125 YearsNHGRIMetabolism
12-HG-0022Inherited Diseases, Caregiving, and Social NetworksCompleted Study; data analyses ongoing18-125 YearsNHGRIMetabolism
12-H-0110An Open-label, Non-Randomized, Single-Arm Pilot Study to Evaluate the Effectiveness of Etidronate Treatment for Arterial Calcifications due to Deficiency in CD73 (ACDC)Completed Study; data analyses ongoing18-80 YearsNHLBIMetabolism
11-M-0045Development of Magnetic Resonance Spectroscopic Imaging Techniques for Imaging Metabolites in Human Brain and MuscleParticipants currently recruited/enrolled18-65 YearsNIMH Metabolism
11-CH-0078Evaluation of Cortisol Resistance in Young Endurance-Trained and Elderly MenCompleted Study; data analyses ongoing18-30 YearsNICHDMineral
11-C-0242Collection of Blood from Patients with Cancer, Other Tumors, or Tumor Predisposition Syndromes for Analysis of Genetic Differences in Drug DispositionParticipants currently recruited/enrolled3-125 YearsNCI Metabolism
09-DK-0081Selective Reduction of Dietary Carbohydrate Versus Fat: Effects on Metabolism, Endocrine Physiology, Brain Activity and Reward CircuitryCompleted Study; data analyses ongoing18-45 YearsNIDDKMetabolism
07-DK-N215Study of Short-Term Metabolic Adaptation: Prediction of Weight Change and Effects of Macronutrient ManipulationsCompleted Study; data analyses ongoing18-55 YearsNIDDKMetabolism
07-DK-0077Study of the Phenotype of Overweight and Obese AdultsParticipants currently recruited/enrolled18-100 YearsNIDDKMetabolism
07-CH-0008Prospective, Open-Label, Multicenter, International Study of Mifepristone for Symptomatic Treatment of Cushing's Syndrome Caused by Ectopic Adrenal Corticotrophin Hormone (ACTH) SecretionCompleted Study; data analyses ongoing18-85 YearsNICHDMineral
06-HG-0055Functional Imaging in Subjects with Glucocerebrosidase MutationsCompleted Study; data analyses ongoing18-125 YearsNHGRIMetabolism
05-M-0144MRS (Magnetic Resonance Spectroscopy) Measurement of Glutamate and GABA Metabolism in BrainParticipants currently recruited/enrolled18-65 YearsNIMH Metabolism
04-HG-0127Clinical and Basic Investigations of Methylmalonic Acidemia (MMA) and Related DisordersParticipants currently recruited/enrolled0-125 YearsNHGRIMetabolism
03-H-0280Disease Pathogenesis and Natural History of Lipid DisordersParticipants currently recruited/enrolled2-100 YearsNHLBIMetabolism
03-E-0099Pathogenic Studies In Families With Twins Or Siblings Discordant For Systemic Rheumatic DisordersCompleted Study; data analyses ongoing2-125 YearsNIEHSMetabolism
03-C-0278A Comparative Study of Pediatric CNS Tumor Activity as Assessed by 18F-FDG PET Imaging and Proton Magnetic Resonance Spectroscopic Imaging (1H-MRSI)Completed Study; data analyses ongoing1-21 YearsNCI Metabolism
02-CH-0311Investigations into Inborn Errors of Cholesterol Synthesis and Related DisordersParticipants currently recruited/enrolled0-125 YearsNICHDMetabolism
01-D-0184A Natural History Study of Bone and Mineral DisordersParticipants currently recruited/enrolled0-125 YearsNIDCRMineral
00-I-0159Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection Syndrome (HIES)Participants currently recruited/enrolled0-125 YearsNIAIDMetabolism
00-HG-0141Clinical, Biochemical, and Molecular Investigations into AlkaptonuriaParticipants currently recruited/enrolled2-125 YearsNHGRIMetabolism
98-CH-0081Clinical and Basic Investigations into Smith-Lemli-Opitz SyndromeCompleted Study; data analyses ongoing0-125 YearsNICHDMetabolism
85-H-0105Cardiovascular Evaluation of Homozygous Familial HypercholesterolemiaCompleted Study; data analyses ongoing2-70 YearsNHLBIMetabolism
79-H-0100Teaching Protocol for the Evaluation of Plasma LipoproteinsNo longer recruiting/follow-up only2-99 YearsNHLBIMetabolism
76-HG-0238Diagnosis and Treatment of Patients with Inborn Errors of Metabolism or Other Genetic DisordersParticipants currently recruited/enrolled0-125 YearsNHGRIMetabolism
76-H-0051Lipoprotein Metabolism in Normal Volunteers and Hyperlipoproteinemic PatientsCompleted Study; data analyses ongoing18-80 YearsNHLBIMetabolism
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