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Protocol Number Title Protocol Status Min-Max Age Institute Keywords
20-C-0107Clinical, Genetic, and Epidemiologic Study of Children and Adults with RASopathiesParticipants currently recruited/enrolled0-125 YearsNCI Brain Developmental Defects
001074-CHCharacterization of Dysmorphology in Subjects with Creatine Transporter DeficiencyParticipants currently recruited/enrolled2-40 YearsNICHDBrain Developmental
000487-CHNatural History Investigation into Biochemical and Phenotypical Aspects of Smith-Lemli-Opitz Syndrome and Related Disorders of Cholesterol MetabolismParticipants currently recruited/enrolled0-125 YearsNICHDDevelopmental Defects
000254-CA Phase II Trial of the Superenhancer Inhibitor Minnelide in Advanced Refractory Adenosquamous Carcinoma of the Pancreas (ASCP)Participants currently recruited/enrolled18-125 YearsNCI Lethal Brain
20-HG-0147An Observational Study of the Developing Brain, Impulsivity and Compulsivity.Participants currently recruited/enrolled6-80 YearsNHGRIBrain Developmental
18-CH-0001Mirror Neuron Network Dysfunction as an Early Biomarker of Neurodevelopmental DisorderParticipants currently recruited/enrolled0-65 YearsNICHDBrain Developmental
18-C-0110Safety Run-In and Phase II Trial of M7824 and Topotecan or Temozolomide in Relapsed Small Cell CancersParticipants currently recruited/enrolled18-125 YearsNCI Lethal Brain
17-CH-0020Observational Study of Males with Creatine Transporter Deficiency (CTD)No longer recruiting/follow-up only2-40 YearsNICHDBrain Developmental
16-H-0132CADASIL Disease DiscoveryCompleted Study; data analyses ongoing18-100 YearsNHLBILethal Brain
16-D-0040Natural History of Craniofacial Anomalies and Developmental Growth VariantsParticipants currently recruited/enrolled2-125 YearsNIDCRDevelopmental Defects
14-HG-0055Study on Moebius Syndrome and Other Congenital Facial Weakness DisordersCompleted Study; data analyses ongoing2-80 YearsNHGRIBrain Defects
13-M-0028Diagnosis of Childhood-onset Behavioral Disorders, Neuropsychiatric Disorders and Neurodevelopmental DisordersParticipants currently recruited/enrolled0-99 YearsNIMH Brain Developmental
11-M-0251A Longitudinal Investigation of the Endocrine and Neurobiologic Events Accompanying PubertyParticipants currently recruited/enrolled7-35 YearsNIMH Brain Developmental
10-M-0112Defining the Brain Phenotype of Children with Williams SyndromeParticipants currently recruited/enrolled5-125 YearsNIMH Brain Developmental
10-M-0027Cognitive Neuroscience of Autism Spectrum DisordersParticipants currently recruited/enrolled5-89 YearsNIMH Brain Developmental
04-HG-0127Clinical and Basic Investigations of Methylmalonic Acidemia (MMA) and Related DisordersParticipants currently recruited/enrolled0-125 YearsNHGRIDevelopmental Defects
03-M-0186The Psychobiology of Temperament: An fMRI StudyParticipants currently recruited/enrolled0-30 YearsNIMH Brain Developmental
02-C-0313Cancer Risk in Xeroderma Pigmentosum HeterozygotesParticipants currently recruited/enrolled0-99 YearsNCI Brain Defects
98-CH-0081Clinical and Basic Investigations into Smith-Lemli-Opitz SyndromeCompleted Study; data analyses ongoing0-125 YearsNICHDBrain Defects
97-CH-0076A Clinical and Genetic Investigation of Pituitary and HYPOTHALAMIC Tumors and Related DisordersParticipants currently recruited/enrolled3-70 YearsNICHDDevelopmental Defects
001018-CHEstablishment of Genomic and Phenotypic Database for Niemann-Pick Disease, Type CParticipants currently recruited/enrolled0-125 YearsNICHDBrain
000978-MState-Dependent Interoception, Value-Based Decision-Making, and IntrospectionRecruitment has not started18-55 YearsNIMH Brain
000942-MA Cognitive Test Battery for Intellectual DisabilitiesParticipants currently recruited/enrolled4-125 YearsNIMH Brain
000922-DADefining Neurobiological Links between Substance Use and Mental IllnessParticipants currently recruited/enrolled18-60 YearsNIDA Brain
000862-CHPilot Study of the Use of Functional Near-Infrared Spectroscopy (fNIRS) Combined with Diffuse Correlation Spectroscopy (DCS) in Neurocognitive Disease as Compared to Healthy Neurotypical ControlsParticipants currently recruited/enrolled0-125 YearsNICHDBrain
000860-CA Phase I/II Study of Zotiraciclib for Recurrent High-Grade Gliomas with Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) MutationsParticipants currently recruited/enrolled18-125 YearsNCI Brain
000824-M[11C]-(R)-Rolipram to Measure cAMP Signaling Before and After KetamineEnrolling by Invitation18-70 YearsNIMH Brain
000784-NAssessing and Improving Quantitative Magnetic Resonance Imaging Metrics in Human SubjectsParticipants currently recruited/enrolled18-125 YearsNINDSBrain
000783-CPhase I/Ib Trial Evaluating the Safety and Efficacy of BET Inhibitor, ZEN003694 with PD-1 Inhibitor, Nivolumab with or without CTLA-4 Inhibitor, Ipilumumab in Solid TumorsParticipants currently recruited/enrolled18-125 YearsNCI Lethal
000776-MAn Open Trial of Transcranial Magnetic Stimulation for Youth with Treatment-Resistant Major Depressive DisorderRecruitment has not started13-17 YearsNIMH Brain
000754-MNIMH Rhythms and Blues Study: A Prospective Natural History Study of Motor Activity, Mood States, and Bipolar DisorderParticipants currently recruited/enrolled12-70 YearsNIMH Brain
000744-HGDevelopment of Virtual Reality-based Interventions to Strengthen Cognitive Skillsets Related to Attention Deficit Hyperactivity Disorder (ADHD): A Randomized Controlled Phase II TrialRecruitment has not started7-14 YearsNHGRIBrain
000736-CCImaging Characterization of the Biomechanical Coupling of Brain and Skull: An Observational StudyParticipants currently recruited/enrolled21-65 YearsCC Brain
000711-NImmunotherapy for Neurological Post-Acute Sequelae of SARS-CoV-2 (IN-PASC)Enrolling by Invitation18-125 YearsNINDSBrain
000687-IVRC 322/DMID 21-0016: A Phase I, Dose Escalation, Open-Label Clinical Trial to Evaluate Safety, Tolerability and Immunogenicity of a Nipah Virus (NiV) mRNA Vaccine, mRNA-1215, in Healthy AdultsParticipants currently recruited/enrolled18-60 YearsNIAIDBrain
000686-CHIntrathecal 2-Hydroxypropyl-Beta-Cyclodextrin for Neurological Decline in Patients with Niemann-Pick Disease Type C1Participants currently recruited/enrolled18-125 YearsNICHDBrain
000678-CRare Tumors and Cancer Predisposition in Individuals and FamiliesParticipants currently recruited/enrolled0-125 YearsNCI Brain
000676-M[18F]PF-06445974 to Image PDE4B in Major Depressive Disorder Using PETParticipants currently recruited/enrolled18-70 YearsNIMH Brain
000674-MAssessment of [18F]SF12051 for Imaging the 18-kDa Translocator Protein (TSPO) in Brain and Whole Body of Healthy SubjectsParticipants currently recruited/enrolled18-99 YearsNIMH Brain
000642-NPhase II Trial of Non-Invasive Intermittent Theta Burst Stimulation of the Dorsolateral Prefrontal Cortex in Functional Movement DisordersParticipants currently recruited/enrolled18-80 YearsNINDSBrain
000631-CInvestigation of the Cognitive Aftereffects of Neurotoxicity in Children and Young Adults with Relapsed/Refractory Hematologic Malignancies who Receive CAR T-cell TherapyRecruitment has not started5-125 YearsNCI Brain
000585-CHAn Open-label Safety, Pharmacokinetic, and Efficacy Study of Miglustat for the Treatment of CLN3 Disease in Patients 17 Years of Age and OlderParticipants currently recruited/enrolled17-125 YearsNICHDBrain
000539-HAddition of JSP191 (c-kit antibody) to Non-myeloablative Hematopoietic Cell Transplantation For Sickle Cell Disease and Beta-ThalassemiaParticipants currently recruited/enrolled4-100 YearsNHLBIBrain
000527-MCNS Correlates of Extended Sleep RestrictionParticipants currently recruited/enrolled18-39 YearsNIMH Brain
000483-MPET Imaging of Cyclooxygenases in Multiple SclerosisParticipants currently recruited/enrolled18-99 YearsNIMH Brain
000479-HObservational Study to Deeply Phenotype Major Organs in Sickle Cell Disease After Curative TherapiesParticipants currently recruited/enrolled18-125 YearsNHLBIBrain
000476-EThe Investigation of Vitamin D and Menstrual Cycles Trial: A Phase II Clinical trialParticipants currently recruited/enrolled19-40 YearsNIEHSBrain
000421-AAIndividual Variations of Taste and Smell Perception in Alcohol Use Disorder (AUD)Recruitment has not started18-65 YearsNIAAABrain
000417-CCCharacterization of the Nociception Phenotype in Individuals with Intellectual DisabilityClinical hold/Recruitment or enrollment suspended8-30 YearsCC Brain
000413-HNatural History study of CADASILParticipants currently recruited/enrolled18-100 YearsNHLBIBrain
000406-AAAddictions Neuroclinical AssessmentEnrolling by Invitation18-125 YearsNIAAABrain
000378-MIdentifying decision making parameters in healthy volunteers (HV) and anxiety patients (AD)Completed Study; data analyses ongoing18-50 YearsNIMH Brain
000344-DKNatural History Study of Parathyroid DisordersParticipants currently recruited/enrolled0-125 YearsNIDDKDefects
000337-CNatural History Study of KSHV-Associated Multicentric Castleman's DiseaseParticipants currently recruited/enrolled18-125 YearsNCI Brain
000317-CA Phase II, Open-Label Trial of PT-112 in Subjects with Thymoma and Thymic CarcinomaParticipants currently recruited/enrolled18-125 YearsNCI Brain
000264-CA Pharmacodynamics-Driven Trial of Talazoparib, an Oral PARP Inhibitor, in Patients With Advanced Solid Tumors and Aberrations in Genes Involved in DNA Damage ResponseParticipants currently recruited/enrolled18-125 YearsNCI Lethal
000224-CHDevelopment of a Wearable Point of Care Monitoring Device for Pediatric Obstructive Sleep ApneaParticipants currently recruited/enrolled3-12 YearsNICHDBrain
000196-NTask-dependent Effects of TMS on the Neural Biomarkers of Episodic MemoryParticipants currently recruited/enrolled18-40 YearsNINDSBrain
000193-CPhase 1 Study of Copanlisib with Dose-adjusted EPOCH-R in Relapsed and Refractory Burkitt Lymphoma and other High-Grade B-cell LymphomasClinical hold/Recruitment or enrollment suspended18-125 YearsNCI Brain
000141-DCDeep Phenotyping of Hearing Instability Disorders: Cohort Establishment, Biomarker Identification, Development of Novel Phenotyping Measures, and Discovery of Therapeutic TargetsParticipants currently recruited/enrolled18-80 YearsNIDCDBrain
000126-NA Pilot Study of NT-I7, a Long-Acting Recombinant IL-7 Molecule, as an Immune Reconstitution Strategy for Lymphopenia in Patients with Progressive Multifocal LeukoencephalopathyParticipants currently recruited/enrolled18-125 YearsNINDSBrain
000101-MAn Investigation of the Antidepressant Effects of the mGlu2/3 receptor antagonist TS-161 in Treatment-Resistant DepressionParticipants currently recruited/enrolled18-65 YearsNIMH Brain
000094-NAn Observational Study of Neurologic Function After COVID -19 InfectionNo longer recruiting/follow-up only18-125 YearsNINDSBrain
000085-CAssessing Sleep and Circadian Rhythms in Primary Brain Tumors Patients: An Observational StudyEnrolling by Invitation18-99 YearsNCI Brain
000079-DKThe Role of 68-Gallium-DOTATATE-PET/CT in the Imaging of Metastatic Thyroid CancerParticipants currently recruited/enrolled18-125 YearsNIDDKBrain
000057-CA Phase 1 Study of AZD8186 in Combination with Docetaxel in Patients with PTEN Mutated or PIK3CB Mutated Advanced Solid Tumors, Potentially Amenable to DocetaxelCompleted Study; data analyses ongoing18-125 YearsNCI Defects
000051-NNIH Investigative Deep Phenotyping Study of Gulf War Veteran Health (Project NIH IN-DEPTH)Participants currently recruited/enrolled48-70 YearsNINDSBrain
22-C-0003Feasibility of Evaluating Abemaciclib Neuropharmacokinetics of Diffuse Midline Glioma Using Intratumoral MicrodialysisParticipants currently recruited/enrolled18-39 YearsNCI Brain
21-N-0016Phase I/II Study of Teriflunomide in HTLV-1 Associated Myelopathy/Tropical Spastic ParaparesisParticipants currently recruited/enrolled18-125 YearsNINDSBrain
21-N-0010A Phase 2 Clinical Trial of Tolebrutinib, a Brain-penetrant Bruton's Tyrosine Kinase Inhibitor, for the Modulation of Chronically Inflamed White Matter Lesions in Multiple SclerosisNo longer recruiting/follow-up only18-125 YearsNINDSBrain
21-M-0031A Feasibility Study of Transcranial Electric Stimulation Therapy (TEST) for treatment resistant depression (TRD)Participants currently recruited/enrolled25-64 YearsNIMH Brain
21-M-0018Characterization of an Optically Pumped Magnetometer (OPM) Magnetoencephalography (MEG) ArrayParticipants currently recruited/enrolled18-65 YearsNIMH Brain
21-I-0029Natural history, epidemiology and pathogenesis of severe HPV-related diseases (Neptune)Participants currently recruited/enrolled3-125 YearsNIAIDDefects
21-C-0019Phase I Study of Anti-CD22 Chimeric Receptor T Cells in Patients with Relapsed/Refractory Hairy Cell Leukemia and VariantParticipants currently recruited/enrolled18-125 YearsNCI Brain
21-C-0017Magnetic Resonance Image (MRI) Guided High Energy Ultrasound for Focal Prostate Cancer AblationRecruitment has not started18-125 YearsNCI Brain
21-C-0015Phase II Trial Evaluating the Association of Peripheral Blood Immunologic Response to Therapeutic Response to Adjuvant Treatment with Immune Checkpoint Inhibition (ICI) in Patients with Newly Diagnosed Glioblastoma or GliosarcomaParticipants currently recruited/enrolled18-125 YearsNCI Brain
21-C-0007A Phase I/II Study of Combination Immunotherapy for Advanced Cancers Including HPV-Associated Malignancies, Small Bowel, and Colon CancersParticipants currently recruited/enrolled18-125 YearsNCI Brain
20-N-0105Layer-specific Contribution to Consolidation of Skill Learning in the Primary Motor CortexParticipants currently recruited/enrolled18-50 YearsNINDSBrain
20-N-0077Study of Volition: Behavioral analysis and Clinical Neurophysiological AnalysisParticipants currently recruited/enrolled25-45 YearsNINDSBrain
20-N-0060Mechanisms Underlying the Beneficial Effects of Naps on Motor LearningParticipants currently recruited/enrolled18-80 YearsNINDSBrain
20-N-0048Corticotrophin-Releasing Hormone (CRH) Stimulation for 18F-FDG-PET Detection of Pituitary Adenoma in Cushing's DiseaseRecruitment has not started8-125 YearsNINDSBrain
20-M-0166Electrophysiologic Sleep Phenotyping and Sleep-Dependent Neuro-maturation in Clinical and Healthy Pediatric PopulationsParticipants currently recruited/enrolled0-8 YearsNIMH Brain
20-M-0159Role of GABAergic Transmission in Auditory Processing in Autism Spectrum DisorderParticipants currently recruited/enrolled14-25 YearsNIMH Brain
20-M-0157PET Imaging of Cyclooxygenase in Participants with Major Depressive Disorder (MDD)Participants currently recruited/enrolled18-70 YearsNIMH Brain
20-M-0082Phase 1 Study: PET Imaging of Cyclooxygenases in Neurodegenerative Brain DiseaseParticipants currently recruited/enrolled18-99 YearsNIMH Brain
20-I-0084Sample Collection for Systems Evaluation of Patients with Unknown or Incompletely Characterized Immune DefectsParticipants currently recruited/enrolled2-125 YearsNIAIDDefects
20-HG-0120Acute Infection in Mitochondrial Disease: An Observational Prospective Natural History Study of Metabolism, Infection and Immunity During the COVID19 PandemicParticipants currently recruited/enrolled0-125 YearsNHGRIDevelopmental
20-H-0141Long-term Follow-up of Subjects With Sickle Cell Disease Treated With Ex Vivo Gene Therapy Using Autologous Hematopoietic Stem Cells Transduced With a Lentiviral VectorEnrolling by Invitation18-125 YearsNHLBIBrain
20-CC-0113Cardiopulmonary Inflammation and Multi-System Imaging During the Clinical Course of COVID-19 Infection in Asymptomatic and Symptomatic Persons (COVID ARC 19)No longer recruiting/follow-up only18-80 YearsCC Brain
20-C-0142A Phase II Study of Bintrafusp alfa (M7824) in Checkpoint Inhibitor Naive and Refractory Subjects with Urothelial CarcinomaCompleted Study; data analyses ongoing18-125 YearsNCI Lethal
20-C-0127A Phase 1 Study of Romidepsin, CC-486 (5-azacitidine), dexamethasone, and lenalidomide (RAdR) for relapsed/refractory T-cell malignanciesParticipants currently recruited/enrolled18-125 YearsNCI Brain
20-C-0106Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients with BAP1 Tumor Predisposition SyndromeParticipants currently recruited/enrolled30-125 YearsNCI Brain
20-C-0069A First-In-Human Phase I Single-Agent Dose-Escalation, Food Effect and Dose Expansion Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System NeoplasmsParticipants currently recruited/enrolled18-125 YearsNCI Brain
20-C-0065A Phase II Feasibility Trial Using Immersive Virtual Reality (VR) at the Time of Clinical Evaluation to Improve Psychological Distress and Anxiety in Primary Brain Tumor (PBT) PatientsParticipants currently recruited/enrolled18-125 YearsNCI Brain
20-C-0027A Phase I Clinical Trial of Selinexor (KPT-330) in Combination with Temozolomide and Radiation Therapy in Patients with Newly Diagnosed GlioblastomaParticipants currently recruited/enrolled18-125 YearsNCI Brain
20-C-0023First-in-Human Phase I Trial to Investigate the Safety, Tolerability, Pharmacokinetics, Biological and Clinical Activity of Metarrestin (ML-246) in Subjects with Metastatic Solid TumorsParticipants currently recruited/enrolled12-125 YearsNCI Brain
20-C-0012A Phase I Study of Bintrafusp alfa (M7824) and NHS-IL12 (M9241) Alone and in Combination with Stereotactic Body Radiation Therapy (SBRT) in Adults with Metastatic Non-Prostate Genitourinary MalignanciesParticipants currently recruited/enrolled18-125 YearsNCI Lethal
20-AG-0087Ketone ester effects on biomarkers of brain metabolism and cognitive performance in cognitively intact adults (Bullet) 55 years old. A double-blinded randomized controlled clinical trialParticipants currently recruited/enrolled55-125 YearsNIA Brain
20-AA-0057The Effect of Acute Alcohol Intoxication on Neural Processes During Decisions to Engage in HIV Risk BehaviorsParticipants currently recruited/enrolled21-65 YearsNIAAABrain
19-NR-0098Patient-Centered Assessment of Symptoms and OutcomesParticipants currently recruited/enrolled18-125 YearsNINR Brain
19-N-0124Anakinra for the Treatment of Chronically Inflamed White Matter Lesions in Multiple SclerosisParticipants currently recruited/enrolled18-120 YearsNINDSBrain
19-N-0114Modulating the Hippocampal and Striatal Memory Networks with rTMSCompleted Study; data analyses ongoing18-40 YearsNINDSBrain
19-N-0081A Traveling Subject Study of Replicability in Conventional and Advanced MRI MS BiomarkersCompleted Study; data analyses ongoing18-125 YearsNINDSBrain
19-N-0036Exploring the Relationship Between Brain Asymmetry and AttentionCompleted Study; data analyses ongoing18-35 YearsNINDSBrain
19-M-0107The Mechanism of Action Underlying Ketamine's Antidepressant Effects: An Investigation of the AMPA Throughput Theory in Patients with Treatment-Resistant Major DepressionParticipants currently recruited/enrolled18-70 YearsNIMH Brain
19-M-0095PET Imaging of Neuroinflammation in Neurodegenerative Diseases via a Novel TSPO RadioligandParticipants currently recruited/enrolled18-125 YearsNIMH Brain
19-M-0073Safety and Feasibility of Individualized Low Amplitude Seizure Therapy (iLAST)Participants currently recruited/enrolled22-70 YearsNIMH Brain
19-M-0054Mapping the Phenotype in Adults with Phelan-McDermid SyndromeCompleted Study; data analyses ongoing0-125 YearsNIMH Developmental
19-I-0015Phase 1/2 Randomized, Double-Blind, Placebo-Controlled Study of Safety and Efficacy of Abatacept for Treating Chronic Cytopenia in Cytotoxic T-lymphocyte Antigen 4 (CTLA4) HaploinsufficiencyParticipants currently recruited/enrolled8-65 YearsNIAIDBrain
19-HG-0101A Phase 1/2 Study of Intravenous Gene Transfer with an AAV9 Vector Expressing Human Beta-galactosidase in Type I and Type II GM1 GangliosidosisNo longer recruiting/follow-up only0-12 YearsNHGRIBrain
19-DA-N019Outcome Inference in the Sensory Preconditioning Task in Opioid-use DisorderParticipants currently recruited/enrolled21-60 YearsNIDA Brain
19-C-0103A Study of Temozolomide, Etoposide, Doxil, Dexamethasone, Ibrutinib, and Rituximab (TEDDI-R) in Aggressive B-cell Lymphomas with Secondary Involvement of the Central Nervous System (CNS)Participants currently recruited/enrolled18-125 YearsNCI Brain
19-C-0096Studying the Biology of IDH-mutant Gliomas via Longitudinal Observation of 2-Hydroxyglutarate (2-HG) Using MR SpectroscopyParticipants currently recruited/enrolled18-125 YearsNCI Brain
19-C-0023A Phase II Study of Olaparib (AZD2281) in Patients with Metastatic/Advanced Urothelial Carcinoma and other genitourinary tumors with DNA-Repair DefectsParticipants currently recruited/enrolled18-125 YearsNCI Defects
19-C-0006Phase II Trial Evaluating Nivolumab In Patients With IDH-Mutant Gliomas With And Without Hypermutator PhenotypeParticipants currently recruited/enrolled18-125 YearsNCI Brain
18-N-0133Feasibility of Endosphenoidal Coil Placement for Imaging of the Sella During Transsphenoidal SurgeryParticipants currently recruited/enrolled18-125 YearsNINDSBrain
18-N-0077Cytokine Microdialysis For Real Time Immune Monitoring in Glioblastoma Patients Undergoing Checkpoint BlockadeCompleted Study; data analyses ongoing18-125 YearsNINDSBrain
18-N-0066Investigating Epilepsy: Screening and EvaluationParticipants currently recruited/enrolled8-125 YearsNINDSBrain
18-N-0020The Natural History of Blood-Brain Barrier Disruption in Stroke Patients with White Matter Hyperintensities (A Cohort Study)No longer recruiting/follow-up only18-125 YearsNINDSBrain
18-M-0144The effects of an ER beta agonist (Lilly Compound LY500307) on estradiol-withdrawal-induced mood symptoms in women with past perimenopausal depression.Participants currently recruited/enrolled45-65 YearsNIMH Brain
18-M-0037Characterization and Treatment of Adolescent DepressionParticipants currently recruited/enrolled11-25 YearsNIMH Brain
18-M-0015Development of Non-Invasive Brain Stimulation TechniquesParticipants currently recruited/enrolled18-65 YearsNIMH Brain
18-H-0118Technical and Translational Development of Cardiovascular MRI (CMR)Participants currently recruited/enrolled7-125 YearsNHLBIBrain
18-EI-0046Perception, Sensation, Cognition and Action in HumansParticipants currently recruited/enrolled18-65 YearsNEI Brain
18-DK-0132Brain Dopamine Function in Human ObesityNo longer recruiting/follow-up only18-125 YearsNIDDKBrain
18-DA-N053Imaging Biomarker for Addiction Treatment OutcomeParticipants currently recruited/enrolled21-125 YearsNIDA Brain
18-DA-N042Understanding the Acute Modulation of Brain Activity by Transcranial Magnetic StimulationParticipants currently recruited/enrolled18-60 YearsNIDA Brain
18-CH-0002Investigations of Juvenile Neuronal Ceroid Lipofuscinosis (CLN3)Participants currently recruited/enrolled0-125 YearsNICHDBrain
18-CC-0117PET Imaging of the Dopaminergic and Serotonergic Systems in Treated HIV Positive SubjectsCompleted Study; data analyses ongoing18-70 YearsCC Brain
18-CC-0052Near-infrared Spectroscopy and Electroencephalography to Assess Cortical Activation During Motor Tasks in Infants and Toddlers with or at high-risk for Cerebral Palsy and Autism Spectrum Disorder Compared to Infants and Toddlers with Typical DevelopmentParticipants currently recruited/enrolled0-5 YearsCC Brain
18-C-0125A Phase I Clinical Trial of T cells Expressing a Novel Fully-human Anti-BCMA CAR for Treating Multiple MyelomaNo longer recruiting/follow-up only18-73 YearsNCI Brain
18-C-0080Feasibility and Preliminary Efficacy of an Enhanced Mindfulness Intervention for Children and Young Adults with High Grade or High-Risk Cancer and Their Caregivers: A Pilot Randomized Controlled TrialCompleted Study; data analyses ongoing5-125 YearsNCI Brain
18-AA-0098Investigating a Response Modulation Hypothesis of Socioemotional Processing associated with Alcohol Use DisorderParticipants currently recruited/enrolled21-65 YearsNIAAABrain
17-N-0168Influence of Brain Oscillation-Dependent TMS on Motor FunctionParticipants currently recruited/enrolled18-125 YearsNINDSBrain
17-N-0145PD-1 Inhibition to Determine CNS Reservoir of HIV-InfectionCompleted Study; data analyses ongoing18-120 YearsNINDSBrain
17-N-0131Investigating Complex Neurodegenerative Disorders Related to Amyotrophic Lateral Sclerosis and Frontotemporal DementiaParticipants currently recruited/enrolled18-125 YearsNINDSBrain
17-N-0055Functional Connectivity as a Biomarker of rTMSCompleted Study; data analyses ongoing18-125 YearsNINDSBrain
17-N-0035Clinical and Physiological Studies of Tremor SyndromesCompleted Study; data analyses ongoing18-125 YearsNINDSBrain
17-N-0031Detailed Evaluation of the Neurophysiology of Surround Inhibition in the Human Motor CortexCompleted Study; data analyses ongoing18-70 YearsNINDSBrain
17-M-0181Recruitment and Characterization of Healthy Research Volunteers for NIMH Intramural StudiesParticipants currently recruited/enrolled18-125 YearsNIMH Brain
17-M-0179Evaluation of a Novel PET Radioligand to Image Cyclooxygenase-1 (COX-1)Participants currently recruited/enrolled18-99 YearsNIMH Brain
17-M-0147Concurrent fMRI-guided rTMS and Cognitive Therapy for the Treatment of Major Depressive EpisodesParticipants currently recruited/enrolled18-65 YearsNIMH Brain
17-M-0060Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive DisorderParticipants currently recruited/enrolled18-65 YearsNIMH Brain
17-I-0083Targeting Residual Activity By Precision, Biomarker-Guided Combination Therapies of Multiple Sclerosis (TRAP-MS)Participants currently recruited/enrolled18-125 YearsNIAIDBrain
17-DA-N002Neuroplasticity Following Theta-Burst Stimulation in Cocaine Use DisorderParticipants currently recruited/enrolled18-60 YearsNIDA Brain
17-DA-0093Exploring Gut-Brain and Brain-Gut Interactions in Alcohol Use Disorder via Microbiota Investigations: A Pilot StudyCompleted Study; data analyses ongoing21-70 YearsNIDA Brain
17-CH-0014Pilot Study of Mobile Attention Training in Overweight Female AdolescentsParticipants currently recruited/enrolled12-21 YearsNICHDBrain
17-C-0175CC-4047-BRN-001: A Phase 2 Clinical Study of Pomalidomide (CC-4047) Monotherapy for Children and Young Adults with Recurrent or Progressive Primary Brain TumorsCompleted Study; data analyses ongoing3-20 YearsNCI Brain
17-C-0156Longitudinal Sample Collection and Tracking for the Developmental Therapeutics Clinic, National Cancer InstituteParticipants currently recruited/enrolled18-125 YearsNCI Developmental
17-C-0125Phase 2 Trial of Nivolumab in Epstein-Barr Virus (EBV)-Positive Lymphoproliferative Disorders and EBV-Positive Non-Hodgkin LymphomasParticipants currently recruited/enrolled12-125 YearsNCI Brain
17-C-0115Phase I/II Study of T-DM1 Alone Versus T-DM1 and Metronomic Temozolomide in Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases Following Stereotactic RadiosurgeryNo longer recruiting/follow-up only18-125 YearsNCI Brain
17-C-0102Phase II Trial of the Immune Checkpoint Inhibitor Nivolumab in Patients with Recurrent Select Rare CNS CancersParticipants currently recruited/enrolled18-99 YearsNCI Brain
17-C-0037Phase II Trial of LB100, a Protein Phosphatase 2A Inhibitor, in Recurrent GlioblastomaParticipants currently recruited/enrolled18-125 YearsNCI Brain
17-C-0034A Randomized, Double Blind Phase II Trial of Surgery, Radiation Therapy Plus Temozolomide and Pembrolizumab with and without HSPPC-96 in Newly Diagnosed Glioblastoma (GBM)Completed Study; data analyses ongoing18-125 YearsNCI Brain
17-C-0009Phase I Trial of Zotiraciclib (TG02) Plus Dose-Dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of Zotiraciclib (TG02) plus Temozolomide versus Temozolomide alone in Adults with Recurrent Anaplastic Astrocytoma and GlioblastomaCompleted Study; data analyses ongoing18-125 YearsNCI Brain
17-AT-0075Sensory and Opioid Mechanisms of Affective TouchCompleted Study; data analyses ongoing18-50 YearsNCCIHBrain
17-AA-0178Dopaminergic Modulation of Brain Activation Using Simultaneous PET/Pharmacological MRIEnrolling by Invitation18-55 YearsNIAAABrain
17-AA-0171Nicotinic Receptor Genetic Variation and Alcohol RewardParticipants currently recruited/enrolled21-60 YearsNIAAABrain
17-AA-0114Brain Dopaminergic Signaling in Opioid use Disorders (OUD)Participants currently recruited/enrolled18-80 YearsNIAAABrain
16-N-0170Effects of Prism Adaption and rTMS on Brain Connectivity and Visual RepresentationCompleted Study; data analyses ongoing18-75 YearsNINDSBrain
16-N-0166Deep Brain Stimulation Surgery for Treatment of Focal Hand DystoniaParticipants currently recruited/enrolled22-125 YearsNINDSBrain
16-N-0114The Effect of Corticosteroids on Inflammation at the Edge of Acute Multiple Sclerosis Plaques: An Investigator-Blinded StudyParticipants currently recruited/enrolled18-125 YearsNINDSBrain
16-N-0072A Pilot Study of Adoptive Cellular Immunotherapy for Progressive Multifocal Leukoencephalopathy with Ex Vivo Generated Polyomavirus-Specific T-cellsCompleted Study; data analyses ongoing18-125 YearsNINDSBrain
16-N-0064Cholinergic Receptor Imaging in DystoniaCompleted Study; data analyses ongoing18-125 YearsNINDSBrain
16-N-0058Myalgic Encephalomyelitis/Chronic Fatigue SyndromeCompleted Study; data analyses ongoing18-60 YearsNINDSBrain
16-N-0055The Pathological Basis of MRI Signal Changes in Multiple Sclerosis: A Longitudinal In Vivo-to-Postmortem StudyParticipants currently recruited/enrolled18-125 YearsNINDSBrain
16-N-0041Tumor Related EpilepsyParticipants currently recruited/enrolled8-125 YearsNINDSBrain
16-N-0031An All-Night Functional Magnetic Resonance Imaging Sleep Study With Auditory StimuliParticipants currently recruited/enrolled18-34 YearsNINDSBrain
16-HG-0156The Natural History, Physiology, Microbiome and Biochemistry Studies of Propionic AcidemiaParticipants currently recruited/enrolled0-125 YearsNHGRIBrain
16-H-0144Impact of Elastin Mediated Vascular Stiffness on End OrgansParticipants currently recruited/enrolled3-85 YearsNHLBIBrain
16-H-0074Williams Syndrome (WS) and Supravalvular Aortic Stenosis (SVAS) DNA and Tissue BankParticipants currently recruited/enrolled0-85 YearsNHLBIDevelopmental
16-H-0063Williams Syndrome Skin and Vascular Elasticity Study (WS-SAVE Study)Completed Study; data analyses ongoing1-70 YearsNHLBIDevelopmental
16-EI-0090Natural History of Spinocerebellar Ataxia Type 7 (SCA7)Participants currently recruited/enrolled12-125 YearsNEI Brain
16-E-0157CaREFREE Study (Calorie Restriction, Environment and Fitness: Reproductive Effects Evaluation Study)Completed Study; data analyses ongoing18-28 YearsNIEHSBrain
16-CH-0103Evaluation of Patients with Genetic DisordersParticipants currently recruited/enrolled0-125 YearsNICHDDevelopmental
16-CC-0149Dopamine and Motor Learning in Cerebral PalsyParticipants currently recruited/enrolled5-25 YearsCC Brain
16-C-0151Evaluation of the Natural History of and Specimen Banking for Patients with Tumors of the Central Nervous SystemParticipants currently recruited/enrolled18-125 YearsNCI Brain
16-C-0097Phase 1 Trial of Panobinostat in Children with Diffuse Intrinsic Pontine GliomaCompleted Study; data analyses ongoing2-21 YearsNCI Brain
16-C-0081A Phase I Dose Escalation Trial of Re-Irradiation in Good Prognosis Recurrent GlioblastomaNo longer recruiting/follow-up only18-125 YearsNCI Brain
16-C-0034A Phase II Trial of Oral Pazopanib plus Oral Topotecan Metronomic Antiangiogenic Therapy for Recurrent Glioblastoma Multiforme (A) without Prior Bevacizumab Exposure and (B) after Failing Prior BevacizumabCompleted Study; data analyses ongoing18-125 YearsNCI Brain
16-C-0011A Phase I-II Trial of Everolimus and Sorafenib in Patients with Recurrent High-Grade GliomasCompleted Study; data analyses ongoing18-125 YearsNCI Brain
16-C-0009Phase II Trial of Carboplatin and Bevacizumab for the Treatment of Recurrent Low-Grade and Anaplastic Supratentorial, Infratentorial and Spinal Cord Ependymoma in Adults: A Multi-Center TrialCompleted Study; data analyses ongoing18-125 YearsNCI Brain
16-AT-0136Effects of External Ear Stimulation on Pain Perception and MoodParticipants currently recruited/enrolled18-50 YearsNCCIHBrain
16-AA-0059Characterization of Brain Amyloid-beta (A-beta) Retention During Wakefulness And Following Emergence From Sleep In Healthy SubjectsCompleted Study; data analyses ongoing18-40 YearsNIAAABrain
16-AA-0037Effect of Opioid Receptor Modulation on Alcohol Self-Administration and Neural Response to Alcohol Cues in Heavy Drinkers: Role of OPRM1 Gene VariationParticipants currently recruited/enrolled21-60 YearsNIAAABrain
15-N-0177Investigation of Blood-Brain-Barrier Breakdown Using Manganese Magnetic Resonance Imaging in Drug-Resistant EpilepsyRecruitment has not started18-60 YearsNINDSBrain
15-N-0167Propensity to develop plasticity in the parieto-motor network in dystonia from the perspective of abnormal high-order motor processingCompleted Study; data analyses ongoing18-65 YearsNINDSBrain
15-N-0156In Vivo Characterization of Inflammation with Ferumoxytol, an Ultrasmall Superparamagnetic Iron Oxide Nanoparticle, on 7 Tesla Magnetic Resonance ImagingCompleted Study; data analyses ongoing18-70 YearsNINDSBrain
15-N-0125Natural History Study of Inflammatory and Infectious Diseases of the Nervous SystemParticipants currently recruited/enrolled2-125 YearsNINDSBrain
15-N-0081A Study of Direct Brain Recording and Stimulation for Memory EnhancementEnrolling by Invitation18-65 YearsNINDSBrain
15-N-0073A Phase I Study of Intrathecal Administration of scAAV9/JeT-GAN for the Treatment of Giant Axonal NeuropathyParticipants currently recruited/enrolled3-99 YearsNINDSBrain
15-M-0188The Neurobiology of SuicideParticipants currently recruited/enrolled18-70 YearsNIMH Brain
15-M-0151An Investigation of the Antidepressant Effects of the Glycine Receptor Antagonist AV 101 (4-chlorokynurenine) in Major Depressive DisorderCompleted Study; data analyses ongoing18-65 YearsNIMH Brain
15-M-0139Mapping the Genotype, Phenotype, and Natural History of Phelan McDermid SyndromeParticipants currently recruited/enrolled1-125 YearsNIMH Brain
15-M-0066Influence on Plasticity of Brain TemperatureParticipants currently recruited/enrolled18-50 YearsNIMH Brain
15-DA-N013The Neurobiological Mechanisms of Psilocybin as an Aid in Smoking CessationParticipants currently recruited/enrolled21-65 YearsNIDA Brain
15-CH-0096Children's Growth and Behavior StudyParticipants currently recruited/enrolled8-125 YearsNICHDBrain
15-CC-0164Effect of Exercise Training on Physical, Cognitive and Behavioral Function in Patients with Traumatic Brain InjuryCompleted Study; data analyses ongoing18-79 YearsCC Brain
15-C-0138Phase I Study of Ipilimumab, Nivolumab, and the Combination in Patients with Newly Diagnosed GlioblastomaCompleted Study; data analyses ongoing18-125 YearsNCI Brain
15-AT-0132Neural and Psychological Mechanisms of Pain PerceptionParticipants currently recruited/enrolled18-50 YearsNCCIHBrain
15-AG-0123Intermittent Calorie Restriction, Insulin Resistance, and Biomarkers of Brain FunctionCompleted Study; data analyses ongoing55-70 YearsNIA Brain
15-AA-0203Cross-Sectional and Longitudinal Study of Structural ImagingCompleted Study; data analyses ongoing30-60 YearsNIAAABrain
15-AA-0186Development of Neuroimaging Methods to Assess the Neurobiology of AddictionParticipants currently recruited/enrolled18-125 YearsNIAAABrain
15-AA-0031Human Brain Mapping of the Apparent Diffusion Coefficient (ADC) during Sleep and WakefulnessCompleted Study; data analyses ongoing18-60 YearsNIAAABrain
14-N-0086Deep Brain Stimulation Therapy in Movement DisordersParticipants currently recruited/enrolled18-125 YearsNINDSBrain
14-N-0083Neural Basis of Decision Making Deficits in Traumatic Brain InjuryParticipants currently recruited/enrolled18-60 YearsNINDSBrain
14-HG-0071Clinical and Basic Investigations into Known and Suspected Congenital Disorders of GlycosylationParticipants currently recruited/enrolled1-80 YearsNHGRIBrain
14-H-0155A Phase 1/2 Study Evaluating Gene Therapy by Transplantation of Autologous CD34+ Stem Cells Transduced Ex Vivo with the LentiGlobin BB305 Lentiviral Vector in Subjects with Severe Sickle Cell DiseaseNo longer recruiting/follow-up only18-50 YearsNHLBIBrain
14-C-0157Phase 1 Study of Ibrutinib and Immuno-Chemotherapy Using Temozolomide, Etoposide, Doxil, Dexamethasone, Ibrutinib, Rituximab (TEDDI-R) in Primary CNS LymphomaParticipants currently recruited/enrolled18-125 YearsNCI Brain
14-C-0116A Randomized Controlled Trial Evaluating an Enhanced Physical Activity Intervention to Improve Cognitive Late Effects in Children Treated with Cranial Radiation for Brain TumorsParticipants currently recruited/enrolled8-125 YearsNCI Brain
14-C-0037A Phase 2 Study of the MET Kinase Inhibitor INC280 in Papillary Renal Cell CancerCompleted Study; data analyses ongoing18-125 YearsNCI Brain
14-C-0015Pilot Trial of BMN 673, an Oral PARP Inhibitor, in Patients With Advanced Solid Tumors and Deleterious BRCA MutationsCompleted Study; data analyses ongoing18-125 YearsNCI Lethal
14-AA-0192Brain Inflammation and Function in AlcoholismCompleted Study; data analyses ongoing30-75 YearsNIAAABrain
14-AA-0187Dopamine Rhythms in Health and AddictionClinical hold/Recruitment or enrollment suspended21-55 YearsNIAAABrain
14-AA-0181NIAAA Natural History ProtocolParticipants currently recruited/enrolled18-100 YearsNIAAABrain
14-AA-0144Reliability Of The Human Brain ConnectomeParticipants currently recruited/enrolled18-125 YearsNIAAABrain
14-AA-0080Characterization Imaging Instruments for Addiction Neuroimaging AssessmentsParticipants currently recruited/enrolled18-125 YearsNIAAABrain
14-AA-0066Behavioral and Functional Task Development, Implementation, and TestingParticipants currently recruited/enrolled18-65 YearsNIAAABrain
13-N-0188Natural History and Biomarkers of C9ORF72 Amyotrophic Lateral Sclerosis and Frontotemporal DementiaCompleted Study; data analyses ongoing18-125 YearsNINDSBrain
13-N-0149An Evaluation of HIV-associated Neurocognitive Disorders (HAND) in Virologically Controlled PatientsParticipants currently recruited/enrolled18-125 YearsNINDSBrain
13-N-0140Cerebrospinal Fluid Collection and Repository StorageParticipants currently recruited/enrolled2-125 YearsNINDSBrain
13-N-0017Natural History Study of Progressive Multifocal Leukoencephalopathy (PML)Participants currently recruited/enrolled2-125 YearsNINDSBrain
13-HG-0053The NIH Mini Study: Metabolism, INfection and Immunity in Inborn Errors of Mitochondrial MetabolismParticipants currently recruited/enrolled2-125 YearsNHGRIDevelopmental
13-DA-N485Multimodal Neuroimaging Genetic Biomarkers of Nicotine Addiction SeverityParticipants currently recruited/enrolled18-60 YearsNIDA Brain
13-CH-0001Intrathecal 2-Hydroxypropyl-B-Cyclodextrin in Patients with Niemann-Pick Disease, Type C1Completed Study; data analyses ongoing2-125 YearsNICHDBrain
13-CC-0210Evaluating an Extension Assist Knee Ankle Foot Orthosis to Improve Gait in Children with Movement DisordersParticipants currently recruited/enrolled5-125 YearsCC Brain
13-CC-0110Near-infrared Spectroscopy and Electroencephalography to Assess and Train Cortical Activation During Motor TasksParticipants currently recruited/enrolled5-125 YearsCC Brain
13-C-0152A Phase I Study of Autologous Activated Natural Killer (NK) Cells +/- rhIL15 in Children and Young Adults with Refractory Solid TumorsCompleted Study; data analyses ongoing2-29 YearsNCI Brain
13-AG-0034Phase I, Double-Blind, Placebo-Controlled, Ascending, Single-Dose, Safety, Tolerability and Pharmacokinetic Study of Bisnorcymserine (BNC), a Highly Selective Inhibitor of Butyrylcholinesterase, in Healthy Adult VolunteersCompleted Study; data analyses ongoing55-125 YearsNIA Brain
12-N-0137A Phase 1 Open-Label Dose Escalation Safety Study of Convection Enhanced Delivery (CED) of Adeno-Associated Virus Encoding Glial Cell Line-Derived Neurotrophic Factor (AAV2-GDNF) in Subjects with Advanced Parkinson's Disease.Completed Study; data analyses ongoing18-125 YearsNINDSBrain
12-N-0031Imaging Biomarkers in Parkinson DiseaseCompleted Study; data analyses ongoing18-100 YearsNINDSBrain
12-M-0128TMS Investigations of the Human Visual SystemParticipants currently recruited/enrolled18-50 YearsNIMH Brain
12-HG-0202The Neurobehavioral, Environmental and Genetic Factors Impacting the Clinical Course of Attention Deficit Hyperactivity DisorderParticipants currently recruited/enrolled3-125 YearsNHGRIBrain
12-E-0050The Role of Gonadotropin Pulsations in the Regulation of Puberty and FertilityParticipants currently recruited/enrolled14-125 YearsNIEHSBrain
12-DC-0152Normative Values in Audiovestibular TestingParticipants currently recruited/enrolled5-80 YearsNIDCDBrain
12-DA-N474Identifying Neurobiological Mechanisms that Underlie Acute Nicotine Withdrawal and Drive Early Relapse in SmokersClinical hold/Recruitment or enrollment suspended18-65 YearsNIDA Brain
12-CC-0139Estimation of Brain Biomechanics using MRIParticipants currently recruited/enrolled18-65 YearsCC Brain
11-N-0211Deep Brain Stimulation Surgery for Movement DisordersParticipants currently recruited/enrolled18-125 YearsNINDSBrain
11-N-0084Evaluation and Diagnosis of Potential Research Subjects with Traumatic Brain Injury (TBI)Completed Study; data analyses ongoing18-125 YearsNINDSBrain
11-N-0051Surgery as a Treatment for Medically Intractable EpilepsyParticipants currently recruited/enrolled8-125 YearsNINDSBrain
11-M-0045Development of Magnetic Resonance Spectroscopic Imaging Techniques for Imaging Metabolites in Human Brain and MuscleParticipants currently recruited/enrolled18-65 YearsNIMH Brain
11-I-0007Lentiviral Gene Transfer for Treatment of Children Older Than 2 Years of Age with X-Linked Severe Combined ImmunodeficiencyClinical hold/Recruitment or enrollment suspended2-40 YearsNIAIDDefects
11-CC-0088Effect of Aerobic Exercise Training on Cardiorespiratory Fitness in Patients with Traumatic Brain InjuryCompleted Study; data analyses ongoing21-45 YearsCC Brain
11-C-0255Clinical, Epidemiologic, and Genetic Studies of Li-Fraumeni SyndromeParticipants currently recruited/enrolled0-125 YearsNCI Brain
11-C-0161A Phase I/II Study of the Mitogen Activated Protein Kinase Kinase (MEK) 1 Inhibitor Selumetinib (AZD6244; Hydrogen Sulfate in Children with Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas (PN)No longer recruiting/follow-up only2-18 YearsNCI Brain
10-N-0122Evaluation, Pathogenesis, and Outcome of Subjects with or Suspected Traumatic Brain InjuryCompleted Study; data analyses ongoing18-125 YearsNINDSBrain
10-N-0012Screening Protocol for Patients with StrokeParticipants currently recruited/enrolled18-90 YearsNINDSBrain
10-N-0009Physiological Investigations of Movement DisordersCompleted Study; data analyses ongoing18-125 YearsNINDSBrain
10-M-0047Top-Down Attentional Control of Visual-ProcessingParticipants currently recruited/enrolled18-125 YearsNIMH Brain
10-I-0014The Natural History of Severe Viral Infections and Characterization of Immune DefectsParticipants currently recruited/enrolled2-125 YearsNIAIDDefects
10-HG-0076Mothers' Thoughts about what their Children EatCompleted Study; data analyses ongoing18-100 YearsNHGRIDevelopmental
10-CH-0198Testing and Calibration of Non-Invasive Optical Imaging Technology for Functional Brain ImagingParticipants currently recruited/enrolled18-125 YearsNICHDBrain
10-CC-0150Effects of Rapid-Resisted Exercise on Ambulatory Adults with Traumatic Brain InjuryCompleted Study; data analyses ongoing18-44 YearsCC Brain
10-CC-0118Long Term Clinical Correlates of TBI: Imaging, Biomarkers, and Clinical Phenotyping ParametersParticipants currently recruited/enrolled18-125 YearsCC Brain
10-C-0201Apheresis and CD34+ Selection of Mobilized Peripheral Blood CD34+ Cells from Patients with DOCK8 Deficiency, LAD-1, and GATA2 DeficiencyParticipants currently recruited/enrolled18-40 YearsNCI Defects
10-AG-0423A Pilot Study of Exendin-4 in Alzheimer's DiseaseCompleted Study; data analyses ongoing60-125 YearsNIA Brain
09-M-0176Functional Relevance of Dopamine Receptors in Healthy Controls and Patients with Schizophrenia: Characterization through [11C]NNC-112 and [18F]Fallypride Positron Emission TomographyParticipants currently recruited/enrolled18-90 YearsNIMH Brain
09-I-0032Comprehensive Multimodal Analysis of Patients with Neuroimmunological Diseases of the CNSParticipants currently recruited/enrolled0-99 YearsNIAIDBrain
09-DK-0081Selective Reduction of Dietary Carbohydrate Versus Fat: Effects on Metabolism, Endocrine Physiology, Brain Activity and Reward CircuitryCompleted Study; data analyses ongoing18-45 YearsNIDDKBrain
08-N-0044A Prospective Natural History Study of Patients with Neurofibromatosis Type 2 (NF2).Participants currently recruited/enrolled8-75 YearsNINDSBrain
08-EI-0031Visual Motor CoordinationParticipants currently recruited/enrolled18-125 YearsNEI Brain
08-DK-N191The Effects of Transcranial Direct Current Stimulation (TDCS) on Food Intake and Weight LossParticipants currently recruited/enrolled18-60 YearsNIDDKBrain
08-C-0214A Pilot Study to Evaluate Neuropsychological Outcome Measures and their Relationship with Prognosis in Patients Receiving Radiation Therapy for Brain MetastasesParticipants currently recruited/enrolled18-125 YearsNCI Brain
08-C-0079Natural History Study and Longitudinal Assessment of Children, Adolescents, and Adults with Neurofibromatosis Type 1No longer recruiting/follow-up only0-125 YearsNCI Brain
08-AG-0238Development of 3T Magnetic Resonance Research Methods for NIA StudiesParticipants currently recruited/enrolled18-125 YearsNIA Brain
07-N-0190Neurobiological Studies of Functional Movement Disorders and Non-Epileptic SeizuresNo longer recruiting/follow-up only18-125 YearsNINDSBrain
07-N-0122Modulation of Motor Function by Stimulation of the Central and Peripheral Nervous SystemCompleted Study; data analyses ongoing18-125 YearsNINDSBrain
07-M-0021Development of Functional and Structural Magnetic Resonance Imaging Techniques for the Study of Mood and Anxiety DisordersParticipants currently recruited/enrolled18-65 YearsNIMH Brain
07-I-0033Screening Protocol for Detection and Characterization of Infections and Infection SusceptibilityParticipants currently recruited/enrolled0-125 YearsNIAIDDefects
07-C-0110Analysis of Stored Data Collected from Individuals Administered Neurobehavioral Assessments on IRB-Approved ProtocolsEnrolling by Invitation0-125 YearsNCI Brain
06-M-0214PET Measurement of Regional Rates of Cerebral Protein Synthesis in Subjects with Fragile X SyndromeCompleted Study; data analyses ongoing18-24 YearsNIMH Brain
06-M-0065Neurodevelopmental and Behavioral Phenotyping Screening ProtocolParticipants currently recruited/enrolled0-125 YearsNIMH Developmental
06-HG-0055Functional Imaging in Subjects with Glucocerebrosidase MutationsCompleted Study; data analyses ongoing18-125 YearsNHGRIBrain
06-DA-N415Screening Protocol for the Evaluation of Potential Research SubjectsParticipants currently recruited/enrolled18-125 YearsNIDA Brain
06-CH-0186Evaluation of Biochemical Markers and Clinical Investigation of Niemann-Pick Disease, Type CParticipants currently recruited/enrolled0-125 YearsNICHDBrain
06-C-0219An Exploratory Study of Biologic and Pathophysiologic Effects of Radiation Therapy in Pediatric Patients with Central Nervous System TumorsCompleted Study; data analyses ongoing0-21 YearsNCI Brain
06-C-0213Tissue Procurement Protocol for the Developmental Therapeutics Clinic, National Cancer Institute (NCI)Participants currently recruited/enrolled0-125 YearsNCI Developmental
05-M-0144MRS (Magnetic Resonance Spectroscopy) Measurement of Glutamate and GABA Metabolism in BrainParticipants currently recruited/enrolled18-65 YearsNIMH Brain
05-H-0130Long-Term Evaluation and Follow Up Care of Patients Treated with Allogeneic Stem Cell TransplantsParticipants currently recruited/enrolled7-80 YearsNHLBIBrain
04-C-0275Targeted Oncolytic Virotherapy and Natural History Study of KSHV-Associated Multicentric Castleman's Disease with Laboratory and Clinical Correlates of Disease ActivityNo longer recruiting/follow-up only18-125 YearsNCI Defects
04-C-0238A Phase 2 Study of 17-Allylamino-17-Demethoxygeldanamycin in Patients with Von Hippel Lindau Disease and Renal TumorsCompleted Study; data analyses ongoing18-125 YearsNCI Brain
04-C-0200Urinary and Serum VEGF and MMP Levels in Patients Receiving Radiation Therapy for Glioblastoma Multiforme: Prospective Determination of a Predictive Value for RecurrenceParticipants currently recruited/enrolled18-125 YearsNCI Brain
03-N-0164Evaluation and Treatment of Neurosurgical DisordersParticipants currently recruited/enrolled4-125 YearsNINDSBrain
03-DK-0257Phase II Trial of Effect of Metreleptin Therapy in Severe Insulin ResistanceNo longer recruiting/follow-up only5-125 YearsNIDDKDefects
03-DA-N380Advanced Functional and Structural MRI Techniques for Neuropharmacological ImagingParticipants currently recruited/enrolled18-80 YearsNIDA Brain
03-DA-N379Cognitive Task Development and Implementation for Functional MRI StudiesParticipants currently recruited/enrolled18-65 YearsNIDA Brain
03-C-0278A Comparative Study of Pediatric CNS Tumor Activity as Assessed by 18F-FDG PET Imaging and Proton Magnetic Resonance Spectroscopic Imaging (1H-MRSI)Completed Study; data analyses ongoing1-21 YearsNCI Brain
03-AG-0325The Baltimore Longitudinal Study of Aging(BLSA)Participants currently recruited/enrolled20-125 YearsNIA Brain
02-N-0014Research Study of Specimens Obtained During Epilepsy SurgeryCompleted Study; data analyses ongoing4-125 YearsNINDSBrain
02-M-0321fMRI Investigation of Explicit Cue and Contextual FearCompleted Study; data analyses ongoing18-50 YearsNIMH Brain
02-M-0021Characterization and Pathophysiology of Severe Mood and Behavioral Dysregulation in Children and YouthParticipants currently recruited/enrolled7-60 YearsNIMH Brain
02-HG-0107Natural History of Glycosphingolipid Storage Disorders and Glycoprotein DisordersParticipants currently recruited/enrolled0-125 YearsNHGRIBrain
02-CH-0311Investigations into Inborn Errors of Cholesterol Synthesis and Related DisordersParticipants currently recruited/enrolled0-125 YearsNICHDDefects
02-C-0052Etiologic Investigation of Cancer Susceptibility in Inherited Bone Marrow Failure Syndromes: A Natural History StudyParticipants currently recruited/enrolled0-125 YearsNCI Defects
01-N-0007Evaluation, Pathogenesis, and Treatment of Patients with or at Risk for Cerebrovascular Disease (A Natural History/Disease Pathogenesis Protocol)Participants currently recruited/enrolled18-125 YearsNINDSBrain
01-M-0254The Evaluation of Patients with Mood and Anxiety Disorders and Healthy VolunteersParticipants currently recruited/enrolled3-99 YearsNIMH Brain
01-M-0192Fluoxetine's Effects on Attention and Emotional Memory in Anxious and Depressed Youth and AdultsParticipants currently recruited/enrolled8-65 YearsNIMH Brain
01-HG-0109Natural History Study of the Clinical and Molecular Manifestations of Smith-Magenis Syndrome (SMS)No longer recruiting/follow-up only0-125 YearsNHGRIDevelopmental
00-N-0140A Prospective Natural History Study of VHL Patients with CNS HemangioblastomasNo longer recruiting/follow-up only8-75 YearsNINDSBrain
00-N-0089Genetic Analysis of the Chiari I MalformationCompleted Study; data analyses ongoing1-125 YearsNINDSBrain
00-N-0082Characterization of Brain Morphology and Activity Using Functional and Anatomical MRI ContrastParticipants currently recruited/enrolled18-125 YearsNINDSBrain
00-N-0043Clinical and Molecular Manifestations of Inherited Neurological DisordersParticipants currently recruited/enrolled2-125 YearsNINDSBrain
00-M-0198The Phenomenology and Neurophysiology of Affective Dysregulation in Children and Adolescents with Bipolar DisorderCompleted Study; data analyses ongoing3-58 YearsNIMH Brain
00-M-0085Structural and Functional Imaging of Neuropsychiatric Patients and Normal Volunteers with 3.0 Tesla MRI and Magnetoencephalography (MEG)Participants currently recruited/enrolled18-125 YearsNIMH Brain
00-HG-0153Investigations into Chediak-Higashi Syndrome and Related DisordersParticipants currently recruited/enrolled0-70 YearsNHGRIDefects
00-HG-0141Clinical, Biochemical, and Molecular Investigations into AlkaptonuriaParticipants currently recruited/enrolled2-125 YearsNHGRIBrain
00-CH-0160Clinical and Molecular Analysis of ACTH-Independent Steroid Hormone Production in Adrenocortical TissueCompleted Study; data analyses ongoing3-70 YearsNICHDBrain
97-HG-0192Genetic Studies in the Amish and MennonitesCompleted Study; data analyses ongoing18-125 YearsNHGRIBrain
97-CH-0064Evaluation and Intervention for Ambulation, Growth, and Basilar Invagination in Osteogenesis ImperfectaCompleted Study; data analyses ongoing0-10 YearsNICHDDevelopmental
96-I-0052A Comprehensive Clinical, Microbiological and Immunological Assessment of Patients with Suspected Post Treatment Lyme Disease Syndrome and Selected Control PopulationsParticipants currently recruited/enrolled13-125 YearsNIAIDBrain
95-M-0150A Neurobiological Investigation of Patients with Schizophrenia Spectrum Disorders and Their SiblingsParticipants currently recruited/enrolled18-55 YearsNIMH Brain
93-M-0170Regional Cerebral Blood Flow Studies of Object Perception, Identification, Localization, and MemoryParticipants currently recruited/enrolled18-65 YearsNIMH Brain
93-I-0119Detection and Characterization of Host Defense DefectsParticipants currently recruited/enrolled0-125 YearsNIAIDDefects
92-M-0174The Central Nervous System Effects of Pharmacologically Induced Hypogonadotropic Hypogonadism with and without Estrogen and Progesterone ReplacementCompleted Study; data analyses ongoing18-50 YearsNIMH Brain
91-I-0140Studies of the Pathogenesis of HIV Infection in Human Peripheral Blood Cells and/or Body Fluids in HIV-Infected and HIV-Uninfected VolunteersParticipants currently recruited/enrolled18-125 YearsNIAIDDefects
90-M-0088The Treatment of Menstrually-Related Mood Disorders with the Gonadotropin Releasing Hormone (GnRH) Agonist, Depot Leuprolide Acetate (Lupron)Completed Study; data analyses ongoing18-45 YearsNIMH Brain
90-M-0014Studies of Frontal Lobe Function During Cognitive Stimulation as Measured with Oxygen-15 Water Positron Emission Tomography in Normal Subjects and Patients with Neuropsychiatric DisordersCompleted Study; data analyses ongoing18-90 YearsNIMH Brain
89-N-0045Evaluation of Progression in Multiple Sclerosis by Magnetic Resonance Imaging (MRI)Participants currently recruited/enrolled18-125 YearsNINDSBrain
89-M-0160Inpatient Evaluation of Neuropsychiatric PatientsParticipants currently recruited/enrolled18-125 YearsNIMH Brain
89-M-0006Brain Imaging of Childhood Onset Psychiatric Disorders, Endocrine Disorders and Healthy VolunteersParticipants currently recruited/enrolled3-125 YearsNIMH Brain
89-C-0086Von Hippel-Lindau (VHL): Clinical Manifestations, Diagnosis, Management and Molecular Bases of Inherited Renal and Other Urologic Malignant DisordersParticipants currently recruited/enrolled2-125 YearsNCI Defects
88-CH-0032Specificity of Mother-Infant Interaction: The Influence of Maternal Age, Employment Status, and Parenthood StatusCompleted Study; data analyses ongoing0-23 YearsNICHDDevelopmental
85-I-0127Natural History of Treated Neurocysticercosis and Long-Term OutcomesParticipants currently recruited/enrolled3-99 YearsNIAIDBrain
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