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194 Studies found from all possible combinations of your search terms. Select a protocol that you wish to review.
Please note that only the first 5 legal search words are being processed.
Protocol Number
Title
Protocol Status
Min-Max Age
Institute
Keywords
000757-DK
Natural History of Pregnancy and Pregnancy Outcomes in Metreleptin-Treated vs Untreated Subjects with Lipodystrophy
Participants currently recruited/enrolled
0-125 Years
NIDDK
Leptin of
19-I-0053
Prospective Study to Identify Food-Specific and Component IgE Threshold Levels that Predict Food Allergy in Patients with Elevated Total Serum IgE Levels and Atopic Dermatitis
Participants currently recruited/enrolled
3-21 Years
NIAID
Level of
13-HG-0053
The NIH Mini Study: Metabolism, INfection and Immunity in Inborn Errors of Mitochondrial Metabolism
Participants currently recruited/enrolled
2-125 Years
NHGRI
Level of
09-I-0184
Studies in the Pathogenesis of Systemic Capillary Leak Syndrome
Participants currently recruited/enrolled
0-125 Years
NIAID
Level of
09-DK-0097
Vitamin E Pharmacokinetics and Biomarkers in Normal and Obese Women
Completed Study; data analyses ongoing
18-55 Years
NIDDK
Level of
02-DK-0022
Long-Term Efficacy of Leptin Replacement in Treatment of Lipodystrophy
Completed Study; data analyses ongoing
1-125 Years
NIDDK
Leptin Level
001180-CC
A Phase I/II Trial Evaluating Long-Term Use of a Pediatric Robotic Exoskeleton (P.REX/Agilik) to Improve Gait in Children with Movement Disorders
Recruitment has not started
3-17 Years
CC
of
001092-C
Exploring the Role of Palliative Care in Phase 1 Enrolled Pediatric Oncology Patients
Enrolling by Invitation
18-125 Years
NCI
of
000911-DK
Dinner Time for Obesity and Prediabetes (DTOP)
Recruitment has not started
18-50 Years
NIDDK
of
000889-I
VRC 615: A Phase I, Open-Label, Dose-Escalation Study of the Safety and Pharmacokinetics of a Human Monoclonal Antibody, VRC-HIVMAB-0115-AB (VRC01.23LS), Administered Intravenously or Subcutaneously to Healthy Adults
Participants currently recruited/enrolled
18-60 Years
NIAID
of
000776-M
An Open Trial of Transcranial Magnetic Stimulation for Youth with Treatment-Resistant Major Depressive Disorder
Recruitment has not started
13-17 Years
NIMH
of
000726-C
A Randomized Phase 2 Study of Atezolizumab with or without Selinexor in Alveolar Soft Part Sarcoma (AXIOM)
Participants currently recruited/enrolled
18-125 Years
NCI
of
000696-C
A Phase III, Multicenter, International Study with a Parallel, Randomized, Double-blind, Placebo-controlled, 2 Arm Design to Assess the Efficacy and Safety of Selumetinib in Adult Participants with NF1 who have Symptomatic, Inoperable Plexiform Neurofibr
Participants currently recruited/enrolled
18-120 Years
NCI
Level
000665-DK
A Randomized Double-Blind Placebo-Controlled Study of the LEPR Agonist Antibody REGN4461 for the Treatment of Metabolic Abnormalities in Patients with Familial Partial Lipodystrophy
Participants currently recruited/enrolled
18-125 Years
NIDDK
Leptin
000488-I
Natural History of Systemic and Nasal Mucosal Immunity after Influenza Vaccination in a Pediatric Population
No longer recruiting/follow-up only
2-17 Years
NIAID
of
000417-CC
Characterization of the Nociception Phenotype in Individuals with Intellectual Disability
Clinical hold/Recruitment or enrollment suspended
8-30 Years
CC
Level
000384-I
Analysis of the Immune Response to COVID-19 Vaccination and Outcomes in Individuals With and Without Immune Deficiencies and Dysregulations
Participants currently recruited/enrolled
3-125 Years
NIAID
of
000344-DK
Natural History Study of Parathyroid Disorders
Participants currently recruited/enrolled
0-125 Years
NIDDK
of
000309-C
A Phase II Study of N-803 Alone or in Combination with BN-Brachyury Vaccine or Bintrafusp Alfa (M7824) for Participants with Castration Resistant Prostate Cancer
Recruitment has not started
18-125 Years
NCI
Level
000299-H
Technical Development of Cardiovascular MRI
Participants currently recruited/enrolled
18-125 Years
NHLBI
Level
000291-I
Observational Digital Biomarker Discovery in Respiratory Virus Challenge Studies
Recruitment has not started
18-65 Years
NIAID
Level
000277-C
Imaging and Biopsy of HIV-Infected Individuals Undergoing Analytic Treatment Interruption
Participants currently recruited/enrolled
18-125 Years
NCI
Level
000272-H
Defining the Genetic Etiology of Suppurative Lung Disease in Children and Adults
Participants currently recruited/enrolled
5-45 Years
NHLBI
Level
000268-CC
NIH Intramural Research Program's Pregnancy Registry Protocol for Subjects and Their Partners
Enrolling by Invitation
0-100 Years
CC
of
000251-C
The Effect of Diet and Exercise on ImmuNotherapy and the Microbiome (EDEN)
Participants currently recruited/enrolled
18-125 Years
NCI
of
000247-DK
Evaluation of Patients with Gastrointestinal Disease
Participants currently recruited/enrolled
18-125 Years
NIDDK
of
000108-EI
An Observational Prospective Natural History Study of Stargardt-like Macular Dystrophy (STDG3) Secondary to Mutations in ELOVL4
Participants currently recruited/enrolled
10-125 Years
NEI
Level
000106-CH
Gonadal Tissue Freezing for Fertility Preservation in Individuals at risk for Ovarian Dysfunction and Premature Ovarian Insufficiency
Participants currently recruited/enrolled
4-21 Years
NICHD
of
000101-M
An Investigation of the Antidepressant Effects of the mGlu2/3 receptor antagonist TS-161 in Treatment-Resistant Depression
Participants currently recruited/enrolled
18-65 Years
NIMH
of
000079-DK
The Role of 68-Gallium-DOTATATE-PET/CT in the Imaging of Metastatic Thyroid Cancer
Participants currently recruited/enrolled
18-125 Years
NIDDK
of
000057-C
A Phase 1 Study of AZD8186 in Combination with Docetaxel in Patients with PTEN Mutated or PIK3CB Mutated Advanced Solid Tumors, Potentially Amenable to Docetaxel
Completed Study; data analyses ongoing
18-125 Years
NCI
of
000049-H
Evaluation of the Safety,Tolerability, Pharmacokinetics, and Pharmacodynamics of Long-term Mitapivat Dosing in Subjects with Stable Sickle Cell Disease: An Extension of a Phase I Pilot Study of Mitapivat
No longer recruiting/follow-up only
18-70 Years
NHLBI
of
000045-C
A Phase I Trial of T Cell Receptor Gene Therapy Targeting KK-LC-1 for Gastric, Breast, Cervical, Lung and other KK-LC-1 Positive Epithelial Cancers
Participants currently recruited/enrolled
18-120 Years
NCI
of
21-M-0018
Characterization of an Optically Pumped Magnetometer (OPM) Magnetoencephalography (MEG) Array
Participants currently recruited/enrolled
18-65 Years
NIMH
of
20-M-0157
PET Imaging of Cyclooxygenase in Participants with Major Depressive Disorder (MDD)
Participants currently recruited/enrolled
18-70 Years
NIMH
of
20-H-0141
Long-term Follow-up of Subjects With Sickle Cell Disease Treated With Ex Vivo Gene Therapy Using Autologous Hematopoietic Stem Cells Transduced With a Lentiviral Vector
Enrolling by Invitation
18-125 Years
NHLBI
Level
20-DK-0079
A Randomized, Double-Blinded, Placebo-Controlled Study of REGN4661, A Leptin Receptor Agonist Antibody, In Patients with Generalized Lipodystrophy
No longer recruiting/follow-up only
12-125 Years
NIDDK
Leptin
20-CC-0036
Exploring a Dietary Behavior Intervention in African-Americans at Risk for Cardiovascular Disease: A Community Acceptability and Feasibility Study
Participants currently recruited/enrolled
18-125 Years
CC
Level
20-CC-0031
A single cohort study collecting interval timed incisional epidermal and dermal tissue samples during surgical procedures to profile temporal response of tissue after noxious stimuli.
Completed Study; data analyses ongoing
18-125 Years
CC
Level
20-C-0164
Multiparametric Magnetic Resonance Imaging of the Prostate to Assess Disease Progression and Genomics in Patients Undergoing Active Surveillance for Prostate Cancer
Participants currently recruited/enrolled
18-125 Years
NCI
Level
20-C-0106
Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients with BAP1 Tumor Predisposition Syndrome
Participants currently recruited/enrolled
30-125 Years
NCI
of
20-C-0103
Investigation of the B- and T-cell Repertoire and Immune Response in Patients with Acute and Resolved COVID-19 Infection
Participants currently recruited/enrolled
18-125 Years
NCI
of
20-C-0097
A Phase II, Open-Label Trial of Bintrafusp Alfa (M7824) in Subjects with Thymoma and Thymic Carcinoma
Participants currently recruited/enrolled
18-125 Years
NCI
of
19-M-0107
The Mechanism of Action Underlying Ketamine's Antidepressant Effects: An Investigation of the AMPA Throughput Theory in Patients with Treatment-Resistant Major Depression
Participants currently recruited/enrolled
18-70 Years
NIMH
of
19-H-0097
A Pilot Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Escalating Multiple Oral Doses of AG-348 in Subjects with Stable Sickle Cell Disease
Completed Study; data analyses ongoing
18-70 Years
NHLBI
of
19-CH-0071
An Open-Label Phase 3 Study of the Safety and Efficacy of Pegvisomant in Children with Growth Hormone Excess
Participants currently recruited/enrolled
2-18 Years
NICHD
of
19-C-0137
A Phase II Study of Ipilimumab, Cabozantinib, and NIvolumab in Rare Genitourinary Cancers (ICONIC)
Participants currently recruited/enrolled
18-125 Years
NCI
Level
19-C-0096
Studying the Biology of IDH-mutant Gliomas via Longitudinal Observation of 2-Hydroxyglutarate (2-HG) Using MR Spectroscopy
Participants currently recruited/enrolled
18-125 Years
NCI
Level
18-I-0139
Defining Skin Immunity of a Bite of Key Insect Vectors in Humans
Completed Study; data analyses ongoing
18-64 Years
NIAID
of
18-HG-0064
A Natural History Study of Patients with Generalized Arterial Calcification of Infancy (GACI) or Autosomal Recessive Hypophosphatemic Rickets Type 2 (ARHR2)
Completed Study; data analyses ongoing
0-125 Years
NHGRI
of
18-H-0146
Genotype -Phenotype Correlation of PKLR Variants with Pyruvate Kinase, 2,3-Diphosphglycerate and ATP Activities in Red Blood Cells of Patients with Sickle Cell Disease
Participants currently recruited/enrolled
18-80 Years
NHLBI
Level
18-H-0090
Haplo-identical Transplantation for Severe Aplastic Anemia, Hypo-plastic MDS and PNH using Peripheral Blood Stem Cells and post-transplant Cyclophosphamide for GVHD prophylaxis
Participants currently recruited/enrolled
4-75 Years
NHLBI
of
18-DK-N071
Early Tracking of Childhood Health Determinants Study
Participants currently recruited/enrolled
0-125 Years
NIDDK
of
18-CH-0031
Clinical and Molecular Characteristics of Primary Aldosteronism in Blacks
Participants currently recruited/enrolled
7-70 Years
NICHD
of
18-C-0110
Safety Run-In and Phase II Trial of M7824 and Topotecan or Temozolomide in Relapsed Small Cell Cancers
Participants currently recruited/enrolled
18-125 Years
NCI
Level
18-C-0014
Phase I Trial of 5-aza-4'-thio-2'-Deoxycytidine (Aza-TdC) in Patients with Advanced Solid Tumors
Participants currently recruited/enrolled
18-120 Years
NCI
of
18-AR-0081
Investigation of the Natural History, Genetics, and Pathophysiology of Systemic Juvenile Idiopathic Arthritis, Adult-Onset Still's Disease and Related Inflammatory Conditions
Participants currently recruited/enrolled
0-125 Years
NIAMS
of
17-M-0060
Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive Disorder
Participants currently recruited/enrolled
18-65 Years
NIMH
of
17-I-0067
Sanaria PfSPZ Challenge with Pyrimethamine Chemoprophylaxis (PfSPZ-CVac Approach): Phase 1 Dose Escalation Trial to Determine Safety and Development of Protective Efficacy after Exposure to Only Pre-erythrocytic Stages of Plasmodium falciparum
Completed Study; data analyses ongoing
18-50 Years
NIAID
of
17-EI-0112
A Long-term Follow-up Study of Participants Enrolled in 11-EI-0147: Longitudinal Investigation of Dark Adaptation in Participants with Age-Related Macular Degeneration (DA_AMD)
Participants currently recruited/enrolled
50-125 Years
NEI
of
17-CH-0078
Setmelanotide (RM-493; Rhythm Pharmaceuticals, Inc.) Phase 2 Open-Label Treatment Trials in Patients with Rare Genetic Disorders of Obesity
No longer recruiting/follow-up only
6-100 Years
NICHD
Leptin
17-CH-0020
Observational Study of Males with Creatine Transporter Deficiency (CTD)
No longer recruiting/follow-up only
2-40 Years
NICHD
Level
17-CC-0148
Obtaining Samples from Human Subjects to Facilitate Basic, Translational and Clinical Research
Participants currently recruited/enrolled
18-125 Years
CC
Level
17-C-0137
Leukapheresis for CAR or Adoptive Cell Therapy Manufacturing
Enrolling by Invitation
3-65 Years
NCI
of
17-C-0105
Prospective Study of Clonal Evolution in Follicular Lymphoma
Participants currently recruited/enrolled
18-125 Years
NCI
of
17-C-0066
A Pilot Study to Investigate the Safety and Clinical Activity of Avelumab (MSB0010718C) in Thymoma and Thymic Carcinoma after Progression on Platinum-Based Chemotherapy
Participants currently recruited/enrolled
18-125 Years
NCI
of
17-C-0061
Phase II Trial of Pembrolizumab in Recurrent or Metastatic Medullary Thyroid Cancer
Completed Study; data analyses ongoing
18-125 Years
NCI
of
17-C-0009
Phase I Trial of Zotiraciclib (TG02) Plus Dose-Dense or Metronomic Temozolomide Followed by Randomized Phase II Trial of Zotiraciclib (TG02) plus Temozolomide versus Temozolomide alone in Adults with Recurrent Anaplastic Astrocytoma and Glioblastoma
Completed Study; data analyses ongoing
18-125 Years
NCI
of
17-AA-0171
Nicotinic Receptor Genetic Variation and Alcohol Reward
Participants currently recruited/enrolled
21-60 Years
NIAAA
Level
16-N-0058
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Completed Study; data analyses ongoing
18-60 Years
NINDS
of
16-N-0041
Tumor Related Epilepsy
Participants currently recruited/enrolled
8-125 Years
NINDS
of
16-H-0144
Impact of Elastin Mediated Vascular Stiffness on End Organs
Participants currently recruited/enrolled
3-85 Years
NHLBI
of
16-DK-0038
A Randomized, Double Blind, Placebo-Controlled Study to Assess Efficacy, Safety and Tolerability of ISIS 304801 in Patients with Partial Lipodystrophy with an Open-Label Extension
Completed Study; data analyses ongoing
18-125 Years
NIDDK
Level
16-D-0040
Natural History of Craniofacial Anomalies and Developmental Growth Variants
Participants currently recruited/enrolled
2-125 Years
NIDCR
of
16-CH-0113
Evaluation of Children with Endocrine and Metabolic-Related Conditions
Participants currently recruited/enrolled
0-100 Years
NICHD
of
16-C-0138
Collection of Peripheral Blood Mononuclear Cells (PBMCs) from Healthy Subjects for the Expansion of T Cells for Adoptive Cell Therapy
Participants currently recruited/enrolled
18-99 Years
NCI
Level
16-C-0135
A Pilot Study of Combined Immune Checkpoint Inhibition in combination with Ablative Therapies in Subjects with Hepatocellular Carcinoma (HCC) or Biliary Tract Carcinomas (BTC)
No longer recruiting/follow-up only
18-125 Years
NCI
of
16-C-0097
Phase 1 Trial of Panobinostat in Children with Diffuse Intrinsic Pontine Glioma
Completed Study; data analyses ongoing
2-21 Years
NCI
of
16-C-0073
A Phase 2 Study of Olaparib and Cediranib for the Treatment of Recurrent Ovarian Cancer
Completed Study; data analyses ongoing
18-125 Years
NCI
of
15-N-0126
HERV-K Suppression using Antiretroviral Therapy in Volunteers with Amyotrophic Lateral Sclerosis (ALS)
No longer recruiting/follow-up only
18-125 Years
NINDS
Level
15-I-0162
Natural History and Genetics of Food Allergy and Related Conditions
Participants currently recruited/enrolled
0-99 Years
NIAID
of
15-H-0190
Human Biospecimen Procurement and Analysis to Support Translational Research to Identify Genetic Etiology and Disease Mechanism(s) in Rare Genetic Vascular/Cardiovascular Diseases
Participants currently recruited/enrolled
0-125 Years
NHLBI
of
15-DK-0003
Compassionate Use of Metreleptin in Previously-Treated Patients with Generalized Lipodystrophy
Participants currently recruited/enrolled
0-125 Years
NIDDK
Leptin
15-DK-0002
Compassionate Use of Metreleptin in Previously-Treated Patients with Partial Lipodystrophy
No longer recruiting/follow-up only
0-125 Years
NIDDK
Leptin
15-CC-0091
Pulmonary Effects of Bronchial Segmental Endotoxin Instillation in Humans
Clinical hold/Recruitment or enrollment suspended
18-45 Years
CC
Level
15-C-0141
Gene Therapy Follow up Protocol for Subjects Previously Enrolled in CAR T-Cell Studies
Enrolling by Invitation
18-125 Years
NCI
of
15-C-0116
Phase I Trial of 4'-thio-2'-deoxycytidine (TdCyd) in Patients With Advanced Solid Tumors
Clinical hold/Recruitment or enrollment suspended
18-125 Years
NCI
of
15-C-0099
A Phase 1, Open-Label, Dose-Escalation Study of SNX-5422 and Everolimus in Subjects with Neuroendocrine Tumors
Completed Study; data analyses ongoing
18-100 Years
NCI
Level
15-C-0078
Safety and Feasibility of Stem Cell Gene Transfer Following R-EPOCH for Non-Hodgkin Lymphoma in AIDS Patients Using Peripheral Blood Stem/Progenitor Cells Treated with a Lentivirus Vector-Encoding Multiple Anti-HIV RNAs
No longer recruiting/follow-up only
18-65 Years
NCI
Level
15-C-0075
A Randomized, Placebo-Controlled Phase II Study of Multi-Epitope TARP Peptide Autologous Dendritic Cell Vaccination in Men with Stage D0 Prostate Cancer
Completed Study; data analyses ongoing
18-125 Years
NCI
Level
14-I-0146
The Pathogenesis and Genetics of Disseminated or Refractory Coccidioidomycosis
Participants currently recruited/enrolled
2-100 Years
NIAID
of
14-HG-0055
Study on Moebius Syndrome and Other Congenital Facial Weakness Disorders
Completed Study; data analyses ongoing
2-80 Years
NHGRI
of
14-EI-0064
Whole Exome and Whole Genome Sequencing for Genotyping of Inherited and Congenital Eye Conditions
Participants currently recruited/enrolled
1-125 Years
NEI
of
14-C-0161
Phase I Trial of the Combination of Bortezomib and Clofarabine in Adults with Refractory Solid Tumors, Lymphomas, or Myelodysplastic Syndromes
Participants currently recruited/enrolled
18-125 Years
NCI
of
14-C-0059
A Phase I Trial of T Cells Expressing an Anti-GD2 Chimeric Antigen Receptor in Children and Young Adults with GD2+ Solid Tumors
Completed Study; data analyses ongoing
1-35 Years
NCI
Level
14-AA-0181
NIAAA Natural History Protocol
Participants currently recruited/enrolled
18-100 Years
NIAAA
of
13-DK-0200
The Mechanism of Human Non-Shivering Thermogenesis and Basal Metabolic Rate
Participants currently recruited/enrolled
18-35 Years
NIDDK
Level
13-DK-0057
Short Term Effects of Leptin Withdrawal or Initiation in Lipodystrophy Independent of Energy Intake
Completed Study; data analyses ongoing
14-70 Years
NIDDK
Leptin
13-C-0152
A Phase I Study of Autologous Activated Natural Killer (NK) Cells +/- rhIL15 in Children and Young Adults with Refractory Solid Tumors
Completed Study; data analyses ongoing
2-29 Years
NCI
Level
13-C-0105
Molecular Profiling-based Assignment of Cancer Therapy for Patients With Advanced Solid Tumors
Completed Study; data analyses ongoing
18-120 Years
NCI
of
13-C-0006
Phase I/II Trial Evaluating the Safety and Efficacy of Ruxolitinib in Patients with Smoldering and Chronic Adult T-cell Leukemia (ATL)
Completed Study; data analyses ongoing
18-125 Years
NCI
Level
12-HG-0181
The Clinical Study of Patients with Sex Chromosome Variants
Completed Study; data analyses ongoing
18-125 Years
NHGRI
of
12-DK-0097
Energy Expenditure Responses to Different Temperatures
Participants currently recruited/enrolled
18-75 Years
NIDDK
of
11-I-0109
Viral Infections in Healthy and Immunocompromised Hosts
Participants currently recruited/enrolled
0-125 Years
NIAID
of
11-I-0057
Effect of Interferon Alpha 2b Intensification on HIV-1 Residual Viremia in Individuals Suppressed on Antiretroviral Therapy
Completed Study; data analyses ongoing
18-65 Years
NIAID
Level
11-HG-0238
Weight Management Interactions in a Virtual Clinical Environment
Completed Study; data analyses ongoing
20-50 Years
NHGRI
of
11-CH-0078
Evaluation of Cortisol Resistance in Young Endurance-Trained and Elderly Men
Completed Study; data analyses ongoing
18-30 Years
NICHD
of
11-C-0190
Collection of Tissue Blocks or Slides from Patients with Cancer
Participants currently recruited/enrolled
18-125 Years
NCI
Level
11-C-0096
Pilot Trial of Molecular Profiling and Targeted Therapy for Advanced Non-Small Cell Lung Cancer, Small Cell Lung Cancer, and Thymic Malignancies
No longer recruiting/follow-up only
18-125 Years
NCI
of
10-N-0143
A Prospective Natural History Study of Patients with Syringomyelia
No longer recruiting/follow-up only
18-125 Years
NINDS
Level
10-HG-0065
Whole Genome Medical Sequencing for Gene Discovery
Participants currently recruited/enrolled
0-125 Years
NHGRI
of
10-H-0141
A Phase II Study of Ofatumumab-Based Induction Chemoimmunotherapy Followed by Consolidation Ofatumumab Immunotherapy in Previously Untreated Patients with Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma.
No longer recruiting/follow-up only
18-99 Years
NHLBI
of
10-H-0083
A Phase I Trial of Safety and Immunogenicity of Gardasil Vaccination Post Stem Cell Transplantation in Patients with and without Immunosuppression
Completed Study; data analyses ongoing
18-50 Years
NHLBI
of
10-CC-0149
Comparing Expectorated and Induced Sputum and Pharyngeal Swabs for Cultures, AFB Smears, and Cytokines in Pulmonary Nontuberculous Mycobacterial Infection
Completed Study; data analyses ongoing
18-80 Years
CC
Level
10-CC-0118
Long Term Clinical Correlates of TBI: Imaging, Biomarkers, and Clinical Phenotyping Parameters
Participants currently recruited/enrolled
18-125 Years
CC
Level
10-C-0201
Apheresis and CD34+ Selection of Mobilized Peripheral Blood CD34+ Cells from Patients with DOCK8 Deficiency, LAD-1, and GATA2 Deficiency
Participants currently recruited/enrolled
18-40 Years
NCI
of
10-C-0054
Administration of Anti-CD19-Chimeric-Antigen-Receptor-Transduced T Cells from the Original Transplant Donor to Patients with Recurrent or Persistent B-Cell Malignancies After Allogeneic Stem Cell Transplantation
No longer recruiting/follow-up only
18-75 Years
NCI
Level
10-C-0025
Randomized Phase II Trial of Rituximab with Either Pentostatin or Bendamustine for Multiply Relapsed or Refractory Hairy Cell Leukemia
Participants currently recruited/enrolled
18-125 Years
NCI
of
09-N-0039
A Phase I Study of the Intrathecal Administration of Resiniferatoxin for Treating Severe Refractory Pain Associated with Advanced Cancer
Participants currently recruited/enrolled
18-125 Years
NINDS
Level
09-I-0200
A Phase I Study of MozobilTM in the Treatment of Patients with WHIMS
Participants currently recruited/enrolled
18-75 Years
NIAID
of
09-I-0102
Etiology, Pathogenesis, and Natural History of Idiopathic CD4+ Lymphocytopenia
Participants currently recruited/enrolled
18-125 Years
NIAID
Level
09-I-0086
Screening Protocol for Genetic Diseases of Allergic Inflammation
Participants currently recruited/enrolled
0-99 Years
NIAID
Level
09-I-0032
Comprehensive Multimodal Analysis of Patients with Neuroimmunological Diseases of the CNS
Participants currently recruited/enrolled
0-99 Years
NIAID
of
09-I-0030
Clinical and Immunologic Monitoring of Patients with Known or Suspected HIV Infection
Participants currently recruited/enrolled
18-125 Years
NIAID
of
09-C-0139
A Pilot Study of Vaccination with Epitope-Enhanced TARP Peptide and TARP Peptide-Pulsed Dendritic Cells in the Treatment of Stage D0 Prostate Cancer
Completed Study; data analyses ongoing
18-125 Years
NCI
Level
09-C-0024
A Phase I Study of Quadrivalent Human Papilloma Virus (HPV) (Types 6, 11, 16, 18) Recombinant Vaccine in HIV-Infected and HIV-Negative Pre-Adolescents, Adolescents and Young Adults
Completed Study; data analyses ongoing
12-26 Years
NCI
Level
08-I-0221
Analysis of HIV-1 Replication During Antiretroviral Therapy
Enrolling by Invitation
18-125 Years
NIAID
Level
08-H-0186
Safety and the Anti- Tumor Effects of Escalating Doses of Adoptively Infused Ex Vivo Expanded Autologous Natural Killer (NK) Cells Against Metastatic Cancers or Hematological Malignancies Sensitized to NK-TRAIL Cytotoxicity with Bortezomib
Completed Study; data analyses ongoing
18-70 Years
NHLBI
Level
08-H-0046
Co-Infusion of Umbilical Cord Blood and Haploidentical CD34+ Cells Following Nonmyeloablative Conditioning as Treatment for Severe Aplastic Anemia and MDS Associated with Severe Neutropenia Refractory to Immunosuppressive Therapy
Completed Study; data analyses ongoing
4-75 Years
NHLBI
of
08-EI-0102
Screening Protocol for the Evaluation and Diagnosis of Potential Research Participants
Participants currently recruited/enrolled
2-125 Years
NEI
of
08-EI-0043
Age-Related Eye Disease Study (AREDS) and AREDS2 Follow-Up
No longer recruiting/follow-up only
50-125 Years
NEI
Level
08-DK-N140
Predicting Adaptive Thermogenesis
Completed Study; data analyses ongoing
18-60 Years
NIDDK
Level
08-DK-0173
A Trial of Segmental Stiffening Wires to Improve the Efficiency and Patient Tolerability of Colonoscopy
Completed Study; data analyses ongoing
40-80 Years
NIDDK
Level
08-DK-0098
Natural History of Familial Carcinoid Tumor
Participants currently recruited/enrolled
18-125 Years
NIDDK
of
08-CC-0133
Response and Adaptation to Aerobic Exercise in Patients with Pulmonary Hypertension: Initial Studies for Establishing Guidelines
Completed Study; data analyses ongoing
21-82 Years
CC
Level
08-C-0130
A Phase II Trial of Peginterferon alfa-2b (PEG-Intron) for Neurofibromatosis Type 1 Related Unresectable, Symptomatic or Life-Threatening Plexiform Neurofibromas
Completed Study; data analyses ongoing
0-21 Years
NCI
Level
08-AA-0178
Computer-Assisted Self-Administration of Ethanol (CASE) in Humans
Participants currently recruited/enrolled
21-60 Years
NIAAA
Level
07-H-0142
Research Respiratory Tract Procedures
Participants currently recruited/enrolled
10-125 Years
NHLBI
of
07-H-0005
Pilot Study of Topical Dexamethasone 0.01% Solution for Prevention of Oral Chronic Graft Versus Host Disease
Completed Study; data analyses ongoing
12-110 Years
NHLBI
Level
07-D-0016
Effects of PTH Replacement on Bone in Hypoparathyroidism
Completed Study; data analyses ongoing
18-70 Years
NIDCR
Level
07-C-0121
Phase 2 Study of the C-Met RTK Inhibitor Foretinib (Formerly GSK 1363089) in Subjects with Papillary Renal Cell Carcinoma (PRC)
Completed Study; data analyses ongoing
18-125 Years
NCI
of
06-I-0153
A Pilot Study of Hepatic Fibrosis in HIV/AIDS Patients with Chronically Elevated Transaminases on Antiretroviral Therapy
No longer recruiting/follow-up only
18-100 Years
NIAID
of
06-H-0217
Genetic Disorders of Mucociliary Clearance
Completed Study; data analyses ongoing
2-65 Years
NHLBI
Level
06-C-0014
Prospective Evaluation of Genetic and Epigenetic Alterations in Patients with Thoracic Malignancies
Participants currently recruited/enrolled
2-125 Years
NCI
of
06-AR-0198
A Pilot Pediatric/Adult Study of Gene Expression Profiling and Clinical Characterization of Phototoxicity
Completed Study; data analyses ongoing
8-100 Years
NIAMS
Level
05-H-0130
Long-Term Evaluation and Follow Up Care of Patients Treated with Allogeneic Stem Cell Transplants
Participants currently recruited/enrolled
7-80 Years
NHLBI
of
05-C-0252
Phase III Randomized Study of R-CHOP v. Dose-Adjusted EPOCH-R with Molecular Profiling in Untreated de Novo Diffuse Large B-Cell Lymphomas
Completed Study; data analyses ongoing
18-125 Years
NCI
of
04-N-0056
The Neural Immune Mechanisms and Genetic Influences on Chronic Pelvic Pain in Women with Endometriosis
Completed Study; data analyses ongoing
18-50 Years
NINDS
of
04-CH-0077
Investigations of Bone-Related Connective Tissue Disorders
Completed Study; data analyses ongoing
0-70 Years
NICHD
of
04-C-0165
Data Collection, Clinical Care and Interventions in CCR, NCI
Enrolling by Invitation
0-125 Years
NCI
of
04-AR-0205
Progression of Spinal Fusion in Ankylosing Spondylitis
Completed Study; data analyses ongoing
18-125 Years
NIAMS
Level
03-M-0211
Family Study of Affective and Anxiety Spectrum Disorders
Participants currently recruited/enrolled
7-120 Years
NIMH
Level
03-DK-0257
Phase II Trial of Effect of Metreleptin Therapy in Severe Insulin Resistance
No longer recruiting/follow-up only
5-125 Years
NIDDK
Leptin
02-I-0110
Natural History of Anthrax: A Study of Primary Infected, Recovered, and Exposed (SPoRE) Individuals and Evaluation of AVA Vaccinated Recipients
Participants currently recruited/enrolled
3-125 Years
NIAID
of
02-I-0055
Evaluation, Treatment, and Follow-up of Patients with Lyme Disease
Participants currently recruited/enrolled
2-125 Years
NIAID
of
02-C-0212
Clinical, Genetic, Behavioral, Laboratory and Epidemiologic Characterization of Individuals and Families at High Risk of Breast/Ovarian Cancer
Completed Study; data analyses ongoing
18-100 Years
NCI
of
02-C-0179
Biospecimen Acquisition from Human Subjects
Participants currently recruited/enrolled
18-125 Years
NCI
Level
01-M-0254
The Evaluation of Patients with Mood and Anxiety Disorders and Healthy Volunteers
Participants currently recruited/enrolled
3-99 Years
NIMH
of
01-HG-0109
Natural History Study of the Clinical and Molecular Manifestations of Smith-Magenis Syndrome (SMS)
No longer recruiting/follow-up only
0-125 Years
NHGRI
of
01-DK-N117
Family Investigation of Nephropathy and Diabetes (F.I.N.D.)
Clinical hold/Recruitment or enrollment suspended
18-125 Years
NIDDK
of
01-D-0184
A Natural History Study of Bone and Mineral Disorders
Participants currently recruited/enrolled
0-125 Years
NIDCR
of
01-CC-0045
Studies of Phlebotomy Therapy in Hereditary Hemochromatosis
Participants currently recruited/enrolled
18-125 Years
CC
of
01-AR-0227
Studies of the Natural History of Rheumatic Disease in Minority Communities
Participants currently recruited/enrolled
18-100 Years
NIAMS
of
00-CH-0160
Clinical and Molecular Analysis of ACTH-Independent Steroid Hormone Production in Adrenocortical Tissue
Completed Study; data analyses ongoing
3-70 Years
NICHD
of
00-CH-0136
A Trial of Pamidronate in Children with Osteogenesis Imperfecta
Completed Study; data analyses ongoing
2-17 Years
NICHD
of
00-CH-0093
Diagnosis, Pathophysiology, and Molecular Biology of Pheochromocytoma and Paraganglioma
Participants currently recruited/enrolled
3-125 Years
NICHD
of
99-H-0050
Non-Myeloablative Allogeneic Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Hematologic Malignancies in High Risk Patients and in Patients with Debilitating Hematologic Diseases
Completed Study; data analyses ongoing
2-80 Years
NHLBI
of
99-C-0099
Examination of Clinical and Laboratory Abnormalities in Patients with Defective DNA Repair: Xeroderma Pigmentosum, Cockayne Syndrome, or Trichothiodystrophy
Participants currently recruited/enrolled
0-125 Years
NCI
of
98-D-0145
Screening and Natural History of Patients with Polyostotic Fibrous Dysplasia and the McCune-Albright Syndrome
Participants currently recruited/enrolled
0-100 Years
NIDCR
of
97-I-0096
Evaluation, Treatment, and Monitoring of Patients With Known or Suspected Parasitic Infection
Participants currently recruited/enrolled
3-125 Years
NIAID
of
97-HG-0192
Genetic Studies in the Amish and Mennonites
Completed Study; data analyses ongoing
18-125 Years
NHGRI
of
97-H-0041
Screening Protocol for Subjects Being Evaluated for National Heart, Lung and Blood Institute (NHLBI) Protocols
Enrolling by Invitation
2-125 Years
NHLBI
of
97-CH-0064
Evaluation and Intervention for Ambulation, Growth, and Basilar Invagination in Osteogenesis Imperfecta
Completed Study; data analyses ongoing
0-10 Years
NICHD
Level
96-I-0052
A Comprehensive Clinical, Microbiological and Immunological Assessment of Patients with Suspected Post Treatment Lyme Disease Syndrome and Selected Control Populations
Participants currently recruited/enrolled
13-125 Years
NIAID
of
96-H-0100
Role of Genetic Factors in the Pathogenesis of Lung Disease
Participants currently recruited/enrolled
2-90 Years
NHLBI
of
95-I-0066
Genetic Analysis of Immune Disorders
Participants currently recruited/enrolled
0-125 Years
NIAID
of
95-H-0186
Characterization of the Pathogenesis of Lymphangioleiomyomatosis (LAM)
Participants currently recruited/enrolled
16-125 Years
NHLBI
Level
95-CH-0059
Definition of the Genotype and Clinical Phenotype of Primary Pigmented Nodular Adrenocortical Disease (PPNAD), Carney Complex, Peutz-Jeghers Syndrome and Related Conditions
Completed Study; data analyses ongoing
3-70 Years
NICHD
Level
94-I-0079
Eosinophil Activation and Function in Parasitic Infections and Other Conditions with Increased Tissue or Peripheral Blood Eosinophilia in Humans
Participants currently recruited/enrolled
1-100 Years
NIAID
of
94-AR-0066
Studies of the Pathogenesis and Natural History of Systemic Lupus Erythematosus (SLE)
Participants currently recruited/enrolled
9-125 Years
NIAMS
of
92-I-0125
A Study of Viral Burden in Peripheral Blood Versus Lymphoid and Bone Marrow Tissue in HIV-Infected Individuals
Participants currently recruited/enrolled
18-125 Years
NIAID
Level
92-DK-0033
Pharmacokinetics and Biodistribution of Ascorbic Acid in Healthy Human Subjects
Completed Study; data analyses ongoing
18-35 Years
NIDDK
Level
91-DK-0214
Evaluation of Patients with Liver Disease
Participants currently recruited/enrolled
2-125 Years
NIDDK
of
91-CC-0117
Epidemiology, Infectivity and Natural History of Hepatitis C Virus Infection in a Blood Donor Population
No longer recruiting/follow-up only
18-125 Years
CC
Level
91-AR-0196
Studies on the Natural History and Pathogenesis of Polymyositis, Dermatomyositis, and Related Diseases
Participants currently recruited/enrolled
16-125 Years
NIAMS
of
89-N-0045
Evaluation of Progression in Multiple Sclerosis by Magnetic Resonance Imaging (MRI)
Participants currently recruited/enrolled
18-125 Years
NINDS
Level
89-M-0160
Inpatient Evaluation of Neuropsychiatric Patients
Participants currently recruited/enrolled
18-125 Years
NIMH
of
81-M-0126
The Evaluation of Women with Menstrually Regulated Mood and Behavioral Disorders
Participants currently recruited/enrolled
18-50 Years
NIMH
of
79-C-0111
The Treatment of Stage I and II Carcinoma of the Breast with Mastectomy and Axillary Dissection vs. Excisional Biopsy Axillary Dissection, and Definitive Irradiation
Completed Study; data analyses ongoing
18-125 Years
NCI
of
78-HG-0093
Use of Cysteamine in the Treatment of Cystinosis
Participants currently recruited/enrolled
0-125 Years
NHGRI
Level
78-C-0039
Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of Cancer
No longer recruiting/follow-up only
0-125 Years
NCI
of
77-DK-0096
Studies on Thyroid Nodules and Thyroid Cancer
Participants currently recruited/enrolled
0-125 Years
NIDDK
of
77-DK-0002
Evaluation of Patients with Thyroid Function Disorders
Participants currently recruited/enrolled
0-125 Years
NIDDK
of
76-DK-0006
Natural History of Disorders of Insulin Resistance
Participants currently recruited/enrolled
0-125 Years
NIDDK
Level