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141 Studies found from all possible combinations of your search terms. Select a protocol that you wish to review.
Protocol Number
Title
Protocol Status
Min-Max Age
Institute
Keywords
19-CH-0020
A Phase 1-2 Multi-Center Study to Assess the Efficacy and Safety of Abiraterone Acetate as Adjunctive Therapy in Pre-Pubescent Children with Classic 21-Hydroxylase Deficiency
Recruitment has not started
2-9 Years
NICHD
Congenital 19
19-C-0085
Phase II Trial of Allogeneic Hematopoietic Cell Transplantation for Peripheral T cell Lymphoma
Clinical hold/Recruitment or enrollment suspended
12-125 Years
NCI
Congenital 19
000740-CH
A Phase 3 Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of Chronocort in the Treatment of Participants Aged 16 Years and Over with Congenital Adrenal Hyperplasia
Enrolling by Invitation
18-125 Years
NICHD
Congenital
000494-DK
Natural History of Fontan Associated Liver Disease and the Evaluation of Biomarkers for Disease Severity Assessment
Participants currently recruited/enrolled
18-125 Years
NIDDK
Congenital
000476-E
The Investigation of Vitamin D and Menstrual Cycles Trial: A Phase II Clinical trial
Participants currently recruited/enrolled
19-40 Years
NIEHS
19
000411-CC
A Feasibility Pilot Study of a Virtual Education-Based Transition Intervention to Improve Transition Readiness in Adolescent and Young Adults with Congenital Adrenal Hyperplasia.
Recruitment has not started
16-22 Years
CC
Congenital
000310-CH
A Phase 1/2, First-in-Human, Open-Label, Dose-Escalation Study of the Safety and Efficacy of Gene Therapy for Congenital Adrenal Hyperplasia through Administration of an Adeno-Associated Virus (AAV) Serotype 5-Based Recombinant Vector Encoding the Human
Recruitment has not started
18-125 Years
NICHD
Congenital
000297-CH
A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Crinecerfont (NBI-74788) in Adult Subjects with Classic Congenital Adrenal Hyperplasia, Followed by Open-Label Treatment
Participants currently recruited/enrolled
18-125 Years
NICHD
Congenital
000236-I
A Phase 1 Study of Empagliflozin as Treatment for Severe Congenital Neutropenia Due to G6PC3 Deficiency
Participants currently recruited/enrolled
18-125 Years
NIAID
Congenital
000126-N
A Pilot Study of NT-I7, a Long-Acting Recombinant IL-7 Molecule, as an Immune Reconstitution Strategy for Lymphopenia in Patients with Progressive Multifocal Leukoencephalopathy
Participants currently recruited/enrolled
18-125 Years
NINDS
19
000089-N
Natural History of Post-Coronavirus Disease 19 Convalescence at the National Institutes of Health
Participants currently recruited/enrolled
18-125 Years
NINDS
19
000051-N
NIH Investigative Deep Phenotyping Study of Gulf War Veteran Health (Project NIH IN-DEPTH)
Participants currently recruited/enrolled
48-70 Years
NINDS
19
000037-CC
Development and Evaluation of Techniques for Computer Aided Detection and Diagnosis from Existing Radiologic Images
No longer recruiting/follow-up only
0-125 Years
CC
19
20-I-0145
VRC 323: A Phase I Open-Label Clinical Trial to Evaluate the Dose, Safety, Tolerability and Immunogenicity of an Influenza H10 Stabilized Stem Ferritin Vaccine, VRC-FLUNPF0103-00-VP, in Healthy Adults
Completed Study; data analyses ongoing
18-70 Years
NIAID
19
20-CH-0126
Data Collection Study of Pediatric and Adolescent Gynecology Conditions
Participants currently recruited/enrolled
0-125 Years
NICHD
Congenital
20-CC-0113
Cardiopulmonary Inflammation and Multi-System Imaging During the Clinical Course of COVID-19 Infection in Asymptomatic and Symptomatic Persons (COVID ARC 19)
No longer recruiting/follow-up only
18-80 Years
CC
19
20-C-0070
A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Patients with Inborn Errors of Immunity
Participants currently recruited/enrolled
4-69 Years
NCI
Congenital
20-C-0013
Phase I/II Trial of PLX038 (PEGylated SN38) and Rucaparib in Solid Tumors and Small Cell Cancers
No longer recruiting/follow-up only
18-125 Years
NCI
19
19-NR-0098
Patient-Centered Assessment of Symptoms and Outcomes
Participants currently recruited/enrolled
18-125 Years
NINR
19
19-N-0124
Anakinra for the Treatment of Chronically Inflamed White Matter Lesions in Multiple Sclerosis
Participants currently recruited/enrolled
18-120 Years
NINDS
19
19-N-0114
Modulating the Hippocampal and Striatal Memory Networks with rTMS
Completed Study; data analyses ongoing
18-40 Years
NINDS
19
19-N-0081
A Traveling Subject Study of Replicability in Conventional and Advanced MRI MS Biomarkers
Completed Study; data analyses ongoing
18-125 Years
NINDS
19
19-N-0036
Exploring the Relationship Between Brain Asymmetry and Attention
Completed Study; data analyses ongoing
18-35 Years
NINDS
19
19-M-0107
The Mechanism of Action Underlying Ketamine's Antidepressant Effects: An Investigation of the AMPA Throughput Theory in Patients with Treatment-Resistant Major Depression
Participants currently recruited/enrolled
18-70 Years
NIMH
19
19-M-0095
PET Imaging of Neuroinflammation in Neurodegenerative Diseases via a Novel TSPO Radioligand
Participants currently recruited/enrolled
18-125 Years
NIMH
19
19-M-0079
Evaluation of Novel PET Radioligands as Inflammatory Biomarkers in Rheumatoid Arthritis and Myositis
Participants currently recruited/enrolled
18-99 Years
NIMH
19
19-M-0073
Safety and Feasibility of Individualized Low Amplitude Seizure Therapy (iLAST)
Participants currently recruited/enrolled
22-70 Years
NIMH
19
19-M-0054
Mapping the Phenotype in Adults with Phelan-McDermid Syndrome
Completed Study; data analyses ongoing
0-125 Years
NIMH
19
19-I-0140
A Phase 1 Evaluation of the Safety of Belimumab in People with Idiopathic CD4 Lymphopenia and Autoantibodies (Phoebe)
Participants currently recruited/enrolled
18-70 Years
NIAID
19
19-I-0133
Paradoxical Tuberculosis Reactions in Patients without HIV Infection
Participants currently recruited/enrolled
18-125 Years
NIAID
19
19-I-0126
Systems Analyses of the Immune Response to the Seasonal Influenza Vaccine
Completed Study; data analyses ongoing
18-125 Years
NIAID
19
19-I-0108
Elemental Diet for Treatment of Inflammatory Bowel Disease in Patients with Chronic Granulomatous Disease
Enrolling by Invitation
8-65 Years
NIAID
19
19-I-0093
Collection of Human Biospecimens for Basic and Clinical Research into Globin Variants
Participants currently recruited/enrolled
18-70 Years
NIAID
19
19-I-0084
Skin Immunity Sample Collection Involving Blisters and Biopsies
Recruitment has not started
7-65 Years
NIAID
19
19-I-0080
Haploidentical Transplant for Patients with Chronic Granulomatous Disease (CGD) using Alemtuzumab, Busulfan and TBI with Post-Transplant Cyclophosphamide
Participants currently recruited/enrolled
4-65 Years
NIAID
19
19-I-0069
Phase I Open-Label Study of Safety and Immunogenicity of AD4-HIV Envelope Vaccine Vectors in Healthy Volunteers
Participants currently recruited/enrolled
18-65 Years
NIAID
19
19-I-0058
Mucosal Correlates of Protection After Influenza Viral Challenge of Vaccinated and Unvaccinated Healthy Volunteers
Completed Study; data analyses ongoing
18-55 Years
NIAID
19
19-I-0053
Prospective Study to Identify Food-Specific and Component IgE Threshold Levels that Predict Food Allergy in Patients with Elevated Total Serum IgE Levels and Atopic Dermatitis
Participants currently recruited/enrolled
3-21 Years
NIAID
19
19-I-0027
A Phase 2 Randomized Double-Blinded Placebo-Controlled Study to Evaluate the Safety and Efficacy of Subcutaneous Sarilumab in Improving the Quality of Life in Subjects with Indolent Systemic Mastocytosis
Participants currently recruited/enrolled
18-75 Years
NIAID
19
19-I-0022
A Prospective, Multicenter Study to Compare and Validate Endoscopic, Histologic, Molecular, and Patient-Reported Outcomes in Pediatric and Adult Patients with Eosinophilic Esophagitis (EoE), Gastritis (EG) and Colitis (EC)
Participants currently recruited/enrolled
3-125 Years
NIAID
19
19-I-0015
Phase 1/2 Randomized, Double-Blind, Placebo-Controlled Study of Safety and Efficacy of Abatacept for Treating Chronic Cytopenia in Cytotoxic T-lymphocyte Antigen 4 (CTLA4) Haploinsufficiency
Participants currently recruited/enrolled
8-65 Years
NIAID
19
19-I-0003
A Multicenter, Multi-Outbreak, Randomized, Controlled Safety and Efficacy Study of Investigational Therapeutics for the Treatment of Patients with Ebola Virus Disease
Completed Study; data analyses ongoing
0-99 Years
NIAID
19
19-HG-0101
A Phase 1/2 Study of Intravenous Gene Transfer with an AAV9 Vector Expressing Human Beta-galactosidase in Type I and Type II GM1 Gangliosidosis
No longer recruiting/follow-up only
0-12 Years
NHGRI
19
19-HG-0092
New Approaches for Empowering Studies of Asthma in Populations of African Descent
Completed Study; data analyses ongoing
18-125 Years
NHGRI
19
19-HG-0059
Longitudinal Studies of Patients with FPDMM
Participants currently recruited/enrolled
0-125 Years
NHGRI
19
19-H-0139
Investigation of the Natural Progression of Clonal Hematopoiesis of Indeterminate Potential and Clonal Cytopenia of Undetermined Significance.
Participants currently recruited/enrolled
18-125 Years
NHLBI
19
19-H-0120
Pilot Study for Geospatial Analysis of Neighborhood Environmental Stress in Relation to Biological Markers of Cardiovascular Health and Health Behaviors in Women
Participants currently recruited/enrolled
19-45 Years
NHLBI
19
19-H-0118
Repeat Peripheral Blood Stem Cell Transplantation for Patients with Sickle Cell Disease or Beta-Thalassemia and Falling Donor Myeloid Chimerism Levels
Participants currently recruited/enrolled
2-80 Years
NHLBI
19
19-H-0111
Early Clonal Dynamics During Venetoclax Treatment for Chronic Lymphocytic Leukemia (CLL)
Participants currently recruited/enrolled
18-125 Years
NHLBI
19
19-H-0100
Best Noninvasive Predictor of Renal Function in Assessing Adult Sickle Nephropathy
Completed Study; data analyses ongoing
18-125 Years
NHLBI
19
19-H-0097
A Pilot Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Escalating Multiple Oral Doses of AG-348 in Subjects with Stable Sickle Cell Disease
Completed Study; data analyses ongoing
18-70 Years
NHLBI
19
19-H-0088
NHLBI DIR Transcatheter Mitral Cerclage Annuloplasty Early Feasibility Study
No longer recruiting/follow-up only
21-99 Years
NHLBI
19
19-H-0057
Multiple Patient Program for Lamprene (clofazimine) for the treatment of Non-Tuberculous Mycobacterial (NTM) Infections- CLAM320B2002M
Participants currently recruited/enrolled
18-99 Years
NHLBI
19
19-H-0034
Exploratory Study of Nicotinamide Riboside on Mitochondrial Function in Li-Fraumeni Syndrome
Completed Study; data analyses ongoing
18-70 Years
NHLBI
19
19-H-0001
Response to the SHINGRIX Varicella Zoster Virus (VZV) Vaccine in Chronic Lymphocytic Leukemia (CLL) Patients that are Treatment Na(SqrRoot) ve or Receiving Bruton s-tyrosine Kinase Inhibitor (BTK-I) Therapy
No longer recruiting/follow-up only
18-125 Years
NHLBI
19
19-EI-0056
A Survey Study of Retinitis Pigmentosa (RP) Clinical Measures and Repeatability Testing of Potential Outcome Measures.
Participants currently recruited/enrolled
12-125 Years
NEI
19
19-E-0110
Reproductive Axis Maturation in the Early Post-Menarchal Years: A Pilot Study
Participants currently recruited/enrolled
8-34 Years
NIEHS
19
19-DK-0072
Non-Alcoholic Fatty Liver Disease, the Hepatic Response to Oral Glucose, and the Effect of Semaglutide (NAFLD HEROES)
Participants currently recruited/enrolled
18-125 Years
NIDDK
19
19-DK-0067
Effect of Low Fat versus Low Carbohydrate Diets on Energy Metabolism
Completed Study; data analyses ongoing
18-50 Years
NIDDK
19
19-DK-0066
The Evaluation and Management of Endocrine-Related Conditions and Physiology
Participants currently recruited/enrolled
18-90 Years
NIDDK
19
19-DK-0050
The Use of 124-I-PET/CT Whole Body and Lesional Dosimetry in Differentiated Thyroid Cancer
Participants currently recruited/enrolled
18-125 Years
NIDDK
19
19-DA-N075
Manipulating Ghrelin Signaling via GOAT Inhibition in Alcohol Use Disorder
Participants currently recruited/enrolled
18-70 Years
NIDA
19
19-DA-N019
Outcome Inference in the Sensory Preconditioning Task in Opioid-use Disorder
Participants currently recruited/enrolled
21-60 Years
NIDA
19
19-CH-0071
An Open-Label Phase 3 Study of the Safety and Efficacy of Pegvisomant in Children with Growth Hormone Excess
Participants currently recruited/enrolled
2-18 Years
NICHD
19
19-CH-0051
Long-Term Follow-UP of Survivors of Pediatric Cushing Disease
Participants currently recruited/enrolled
2-90 Years
NICHD
19
19-CH-0026
Randomized, Double-Blind, Placebo-Controlled Study Plus Open Label Extension with a Double-Blind, Placebo-Controlled, Randomized Withdrawal Period of Diazoxide Choline Extended-Release Tablets (DCCR, Soleno Therapeutics, Inc.) in Participants with Prader
No longer recruiting/follow-up only
4-125 Years
NICHD
19
19-CC-0070
Translational Development of Photon-Counting CT Imaging
Completed Study; data analyses ongoing
18-125 Years
CC
19
19-CC-0063
Impact of Steady State Cobicistat and Darunavir/Cobicistat on the Pharmacokinetics and Pharmacodynamics of Oral Anticoagulants (Rivaroxaban, Apixaban) in Healthy Volunteers
Participants currently recruited/enrolled
18-65 Years
CC
19
19-CC-0055
Cardiovascular Disease in HIV and Hepatitis C: Risk Outcomes after Hepatitis C Eradication
Participants currently recruited/enrolled
18-125 Years
CC
19
19-CC-0005
Short or Long Infusion Duration for Platelets: The SOLID Platelet Study
Participants currently recruited/enrolled
18-100 Years
CC
19
19-C-0143
A Phase II Study Using the Administration of Autologous T-Cells Engineered using the Sleeping Beauty Transposon/Transposase System to Express T-Cell Receptors Reactive Against Mutated Neoantigens in Patients with Metastatic Cancer
Participants currently recruited/enrolled
18-70 Years
NCI
19
19-C-0142
Identifying Predictors of Poor Health-Related Quality-of-Life Among Pediatric Hematopoietic Stem Cell Donors
Participants currently recruited/enrolled
5-125 Years
NCI
19
19-C-0138
Phase I/II Study of Lu-177-DOTATATE (Lutathera) in Combination with Olaparib in Inoperable Gastroenteropancreatico Neuroendocrine Tumors (GEP-NET)
Participants currently recruited/enrolled
18-125 Years
NCI
19
19-C-0137
A Phase II Study of Ipilimumab, Cabozantinib, and NIvolumab in Rare Genitourinary Cancers (ICONIC)
Participants currently recruited/enrolled
18-125 Years
NCI
19
19-C-0136
A Phase 2, Randomized, Multicenter Study to Evaluate the Efficacy and Safety of KD025 in Subjects with Chronic Graft Versus Host Disease (CGVHD) After at Least 2 Prior Lines of Systemic Therapy
Completed Study; data analyses ongoing
18-125 Years
NCI
19
19-C-0135
Evaluation of the Natural History and Management of Von Hippel-Lindau (VHL) Associated Pancreatic Neuroendocrine Tumors
Participants currently recruited/enrolled
12-125 Years
NCI
19
19-C-0134
A Phase 1/1b Study of Enhancement of Immune Reconstitution and Vaccine Responses with Administration of Recombinant Human IL-7-hyFc (NT-I7) in Older Subjects Following Chemotherapy
Participants currently recruited/enrolled
60-125 Years
NCI
19
19-C-0132
Incidental Detection of Maternal Neoplasia Through Non-invasive Cell-Free DNA Analysis (IDENTIFY), a Natural History Study
Participants currently recruited/enrolled
18-125 Years
NCI
19
19-C-0131
Development and Psychometric Testing of a Pediatric Chronic Graft- Versus-Host Disease (GVHD) Symptom Scale (PCSS)
Participants currently recruited/enrolled
5-125 Years
NCI
19
19-C-0129
A Phase II Study of Intraperitoneal and Intravenous Paclitaxel Chemotherapy with Oral Capecitabine for Gastric Adenocarcinoma with Peritoneal Carcinomatosis
Participants currently recruited/enrolled
18-125 Years
NCI
19
19-C-0128
A Phase I Study of Mesothelin-Targeted Immunotoxin LMB-100 in Combination with Tofacitinib in Persons with Previously Treated Pancreatic Adenocarcinoma, Cholangiocarcinoma and other Mesothelin Expressing Solid Tumors
Completed Study; data analyses ongoing
18-125 Years
NCI
19
19-C-0127
A Phase II Study of LMB-100 Followed by Pembrolizumab in the Treatment of Adults with Mesothelin-Expressing Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
No longer recruiting/follow-up only
18-125 Years
NCI
19
19-C-0117
A Phase 1 / 2 Single Arm Open-label Clinical Trial of Gavocabtagene Autoleucel (gavo-cel) in Patients with Advanced Mesothelin Expressing Cancer
Participants currently recruited/enrolled
18-120 Years
NCI
19
19-C-0116
A Phase 2 Study of Acalabrutinib with DA-EPOCH-R or R-CHOP for Patients with Untreated Diffuse Large B-cell Lymphoma
Participants currently recruited/enrolled
18-125 Years
NCI
19
19-C-0112
Phase I/II Study De-intensifying Exposure of Post-transplantation Cyclophosphamide as GVHD Prophylaxis after HLA-haploidentical Hematopoietic Cell Transplantation for Hematologic Malignancies
Participants currently recruited/enrolled
12-125 Years
NCI
19
19-C-0104
A Phase II Multi-Institutional Trial to Evaluate Prostate Specific Membrane Antigen (PMSA)-Based PET Imaging of High Risk Prostate Cancer
Participants currently recruited/enrolled
18-125 Years
NCI
19
19-C-0103
A Study of Temozolomide, Etoposide, Doxil, Dexamethasone, Ibrutinib, and Rituximab (TEDDI-R) in Aggressive B-cell Lymphomas with Secondary Involvement of the Central Nervous System (CNS)
Participants currently recruited/enrolled
18-125 Years
NCI
19
19-C-0102
A Phase I Clinical Trial of T-cells Expressing an anti-SLAMF7 CAR for Treating Multiple Myeloma
Completed Study; data analyses ongoing
18-73 Years
NCI
19
19-C-0096
Studying the Biology of IDH-mutant Gliomas via Longitudinal Observation of 2-Hydroxyglutarate (2-HG) Using MR Spectroscopy
Participants currently recruited/enrolled
18-125 Years
NCI
19
19-C-0094
A Phase II Study of Combined Treatment of Durvalumab, Bevacizumab, Tremelimumab and Transarterial Chemoembolization (TACE) in Subjects with Hepatocellular Carcinoma (HCC) or Biliary Tract Carcinoma (BTC)
Participants currently recruited/enrolled
18-125 Years
NCI
19
19-C-0082
Natural History Study of Children and Adults with Chordoma
Participants currently recruited/enrolled
2-125 Years
NCI
19
19-C-0076
A Phase 1 Study of Interleukin-15 in Combination with Avelumab (Bavencio) in Relapsed/Refractory Mature T-cell Malignancies
Completed Study; data analyses ongoing
18-125 Years
NCI
19
19-C-0062
A Phase II Study of Neoadjuvant Androgen Deprivation Therapy Combined with Enzalutamide and Abiraterone Using Multiparametric MRI and 18F-DCFPyL-PET/CT in Newly Diagnosed Prostate Cancer
Participants currently recruited/enrolled
18-125 Years
NCI
19
19-C-0061
A Phase 2 Trial of the MEK Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in Combination with the mTOR Inhibitor Sirolimus for Patients with Unresectable or Metastatic Malignant Peripheral Nerve Sheath Tumors
Participants currently recruited/enrolled
12-125 Years
NCI
19
19-C-0049
Long Term Follow-up of Mesothelioma Patients and Their Family Members with Germline Mutations in BAP1 and Other Genes
Participants currently recruited/enrolled
2-125 Years
NCI
19
19-C-0042
A Phase I Study of Moxetumomab Pasudotox-tdfk (Lumoxiti (TM)) and either Rituximab (Rituxan (R)) or Ruxience for Relapsed Hairy Cell Leukemia
No longer recruiting/follow-up only
18-125 Years
NCI
19
19-C-0041
Birinapant and Intensity Modulated Re-Irradiation Therapy (IMRRT) for Locoregionally Recurrent Head and Neck Squamous Cell Carcinoma (HNSCC)
Participants currently recruited/enrolled
18-125 Years
NCI
19
19-C-0040
Natural History Study of Men at High Genetic Risk for Prostate Cancer
Participants currently recruited/enrolled
30-75 Years
NCI
19
19-C-0039
Perioperative MVT-5873, a Fully Human Monoclonal Antibody Against a CA 19-9 Epitope, for Operable CA 19-9 Producing Pancreatic Cancers, Cholangiocarcinomas, and Metastatic Colorectal Cancers
Completed Study; data analyses ongoing
18-125 Years
NCI
19
19-C-0033
Phase II Study of Nivolumab (anti-PD1), Tadalafil and Oral Vancomycin in Patients with Refractory Primary Hepatocellular Carcinoma or Liver Dominant Metastatic Cancer from Colorectal or Pancreatic Cancers
Completed Study; data analyses ongoing
18-125 Years
NCI
19
19-C-0030
A Phase 2 Study of Response-Adapted Therapy with Copanlisib and Rituximab in Untreated Follicular Lymphoma
Participants currently recruited/enrolled
18-125 Years
NCI
19
19-C-0025
Tissue Acquisition and Genomics Analysis of Breast Cancer and Other Gynecologic Malignancies
Enrolling by Invitation
18-125 Years
NCI
19
19-C-0023
A Phase II Study of Olaparib (AZD2281) in Patients with Metastatic/Advanced Urothelial Carcinoma and other genitourinary tumors with DNA-Repair Defects
Participants currently recruited/enrolled
18-125 Years
NCI
19
19-C-0017
A Phase I/II Study Administering Peripheral Blood Lymphocytes Transduced with a Murine T-Cell Receptor Recognizing the G12D Variant of Mutated RAS in HLA-A*11:01 Patients
Participants currently recruited/enrolled
18-70 Years
NCI
19
19-C-0016
Natural History and Biospecimen Acquisition Study for Children and Adults with Rare Solid Tumors
Participants currently recruited/enrolled
0-125 Years
NCI
19
19-C-0010
A Phase 1 Trial of MK-3475 Plus Ziv-Aflibercept in Patients with Advanced Solid Tumors
Completed Study; data analyses ongoing
18-125 Years
NCI
19
19-C-0006
Phase II Trial Evaluating Nivolumab In Patients With IDH-Mutant Gliomas With And Without Hypermutator Phenotype
Participants currently recruited/enrolled
18-125 Years
NCI
19
19-AT-0089
Sensory Afferents for Deep Pressure Sensation
Completed Study; data analyses ongoing
18-50 Years
NCCIH
19
18-C-0135
Phase II Trial of Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or Dysregulation
Participants currently recruited/enrolled
4-125 Years
NCI
Congenital
17-H-0095
Heart Catheterization Using Magnetic Resonance Imaging (MRI) Fluoroscopy and Passive Guidewires
Participants currently recruited/enrolled
18-125 Years
NHLBI
Congenital
17-C-0012
A Phase I Study of a Combination of MM-398 and Veliparib in solid tumors
Completed Study; data analyses ongoing
18-125 Years
NCI
19
16-I-0053
A Multicenter Study of the Immunogenicity of Recombinant Vesicular Stomatitis Vaccine for Ebola-Zaire (rVSVdeltaG-ZEBOV GP) for Pre-Exposure Prophylaxis in Individuals at Potential Occupational Risk for Ebola Virus Exposure (PREPARE)
No longer recruiting/follow-up only
18-125 Years
NIAID
19
16-DK-0143
Idiosyncratic Liver Injury Associated with Drugs (ILIAD): A Retrospective Study
Participants currently recruited/enrolled
18-125 Years
NIDDK
19
16-CH-0164
A Phase III Extension Study of Efficacy, Safety and Tolerability of Chronocort (Registered) in the Treatment of Congenital Adrenal Hyperplasia
Completed Study; data analyses ongoing
18-80 Years
NICHD
Congenital
16-CC-0112
Impact of Once-Weekly Rifapentine and Isoniazid on the Steady State Pharmacokinetics of Dolutegravir and Darunavir Boosted with Cobicistat in Healthy Volunteers
Completed Study; data analyses ongoing
18-65 Years
CC
19
16-C-0003
Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies
Participants currently recruited/enrolled
4-75 Years
NCI
Congenital
15-H-0016
A Phase II Study Using ACP-196 in Patients with Relapsed/Refractory and Treatment Naive Deletion 17p CLL/SLL: Pharmacodynamic Assessment of BTK Inhibition and Anti-Tumor Response.
No longer recruiting/follow-up only
18-125 Years
NHLBI
19
15-DK-0119
Thyroid Hormone to Induce Non-Insulin Mediated Glucose Disposal in Patients with Insulin Receptor Mutations
Completed Study; data analyses ongoing
12-65 Years
NIDDK
19
15-DK-0108
Natural History of Noncirrhotic Portal Hypertension
Participants currently recruited/enrolled
12-125 Years
NIDDK
Congenital
14-I-0091
Analysis of Patients Treated for Chronic Granulomatous Disease Since January 1, 1995
Completed Study; data analyses ongoing
3-125 Years
NIAID
19
14-I-0089
A Retrospective and Cross-Sectional Analysis of Patients Treated for Severe Combined Immunodeficiency (SCID) Since January 1, 1968
Enrolling by Invitation
2-125 Years
NIAID
19
14-HG-0071
Clinical and Basic Investigations into Known and Suspected Congenital Disorders of Glycosylation
Participants currently recruited/enrolled
1-80 Years
NHGRI
Congenital
14-HG-0055
Study on Moebius Syndrome and Other Congenital Facial Weakness Disorders
Completed Study; data analyses ongoing
2-80 Years
NHGRI
Congenital
14-EI-0064
Whole Exome and Whole Genome Sequencing for Genotyping of Inherited and Congenital Eye Conditions
Participants currently recruited/enrolled
1-125 Years
NEI
Congenital
14-C-0004
A Multicenter Phase 2 Study of the Bruton's Tyrosine Kinase Inhibitor PCI-32765 (Ibrutinib) for Treatment of Relapsed Hairy Cell Leukemia
No longer recruiting/follow-up only
18-125 Years
NCI
19
13-H-0183
Cardiovascular Health and Needs Assessment in Washington D.C. - Development of a Community-Based Behavioral Weight Loss Intervention
Participants currently recruited/enrolled
19-85 Years
NHLBI
19
13-DK-0091
Combination Therapy of Pegylated Interferon Alfa-2a and Tenofovir DF versus Tenofovir DF Monotherapy in HBeAg-Positive and HBeAg-Negative Chronic Hepatitis B
Completed Study; data analyses ongoing
18-125 Years
NIDDK
19
13-DK-0057
Short Term Effects of Leptin Withdrawal or Initiation in Lipodystrophy Independent of Energy Intake
Completed Study; data analyses ongoing
14-70 Years
NIDDK
19
12-C-0112
Phase I Study of T Cells Expressing an Anti-CD19 Chimeric Receptor in Children and Young Adults with B Cell Malignancies
Completed Study; data analyses ongoing
1-30 Years
NCI
19
10-HG-0065
Whole Genome Medical Sequencing for Gene Discovery
Participants currently recruited/enrolled
0-125 Years
NHGRI
Congenital
09-H-0225
Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Severe Congenital Anemias Including Sickle Cell Disease and Beta-Thalassemia
No longer recruiting/follow-up only
2-125 Years
NHLBI
Congenital
08-C-0130
A Phase II Trial of Peginterferon alfa-2b (PEG-Intron) for Neurofibromatosis Type 1 Related Unresectable, Symptomatic or Life-Threatening Plexiform Neurofibromas
Completed Study; data analyses ongoing
0-21 Years
NCI
Congenital
07-C-0110
Analysis of Stored Data Collected from Individuals Administered Neurobehavioral Assessments on IRB-Approved Protocols
Enrolling by Invitation
0-125 Years
NCI
19
06-CH-0011
Natural History Study of Patients with Excess Androgen
Participants currently recruited/enrolled
0-99 Years
NICHD
Congenital
03-H-0170
Nonmyeloablative Allogeneic Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation For Severe Congenital Anemias Including Sickle Cell Disease (SCD) and Beta-Thalassemia
Participants currently recruited/enrolled
2-125 Years
NHLBI
Congenital
03-DK-0256
Inhibition of Intestinal Glucose Absorption by the Bioflavonoid Quercetin in the Obese and in Obese Type 2 Diabetics
Completed Study; data analyses ongoing
18-65 Years
NIDDK
19
03-AG-0325
The Baltimore Longitudinal Study of Aging(BLSA)
Participants currently recruited/enrolled
20-125 Years
NIA
19
02-C-0052
Etiologic Investigation of Cancer Susceptibility in Inherited Bone Marrow Failure Syndromes: A Natural History Study
Participants currently recruited/enrolled
0-125 Years
NCI
Congenital
96-CH-0033
An Open, Randomized, Long-Term Clinical Trial of Flutamide, Testolactone, and Reduced Hydrocortisone Dose vs. Conventional Treatment of Children with Congenital Adrenal Hyperplasia
No longer recruiting/follow-up only
2-18 Years
NICHD
Congenital
94-HG-0132
The Phenotype and Etiology of Proteus Syndrome
Participants currently recruited/enrolled
0-125 Years
NHGRI
Congenital
89-M-0006
Brain Imaging of Childhood Onset Psychiatric Disorders, Endocrine Disorders and Healthy Volunteers
Participants currently recruited/enrolled
3-125 Years
NIMH
Congenital