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164 Studies found from all possible combinations of your search terms. Select a protocol that you wish to review.
Protocol Number Title Protocol Status Min-Max Age Institute Keywords
000740-CHA Phase 3 Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of Chronocort in the Treatment of Participants Aged 16 Years and Over with Congenital Adrenal HyperplasiaEnrolling by Invitation18-125 YearsNICHDCongenital 16
000411-CCA Feasibility Pilot Study of a Virtual Education-Based Transition Intervention to Improve Transition Readiness in Adolescent and Young Adults with Congenital Adrenal Hyperplasia.Recruitment has not started16-22 YearsCC Congenital 16
16-CH-0164A Phase III Extension Study of Efficacy, Safety and Tolerability of Chronocort (Registered) in the Treatment of Congenital Adrenal HyperplasiaCompleted Study; data analyses ongoing18-80 YearsNICHDCongenital 16
16-C-0003Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary ImmunodeficienciesParticipants currently recruited/enrolled4-75 YearsNCI Congenital 16
14-EI-0064Whole Exome and Whole Genome Sequencing for Genotyping of Inherited and Congenital Eye ConditionsParticipants currently recruited/enrolled1-125 YearsNEI Congenital 16
03-H-0170Nonmyeloablative Allogeneic Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation For Severe Congenital Anemias Including Sickle Cell Disease (SCD) and Beta-ThalassemiaParticipants currently recruited/enrolled2-125 YearsNHLBICongenital 16
000687-IVRC 322/DMID 21-0016: A Phase I, Dose Escalation, Open-Label Clinical Trial to Evaluate Safety, Tolerability and Immunogenicity of a Nipah Virus (NiV) mRNA Vaccine, mRNA-1215, in Healthy AdultsParticipants currently recruited/enrolled18-60 YearsNIAID16
000686-CHIntrathecal 2-Hydroxypropyl-Beta-Cyclodextrin for Neurological Decline in Patients with Niemann-Pick Disease Type C1Participants currently recruited/enrolled18-125 YearsNICHD16
000665-DKA Randomized Double-Blind Placebo-Controlled Study of the LEPR Agonist Antibody REGN4461 for the Treatment of Metabolic Abnormalities in Patients with Familial Partial LipodystrophyParticipants currently recruited/enrolled18-125 YearsNIDDK16
000644-CPhase 1/1b Trial of ATR Inhibitor BAY 1895344 in Combination with FOLFIRI in GI Malignancies with a Focus on Metastatic Colorectal and Gastric/Gastroesophageal CancersParticipants currently recruited/enrolled18-125 YearsNCI 16
000494-DKNatural History of Fontan Associated Liver Disease and the Evaluation of Biomarkers for Disease Severity AssessmentParticipants currently recruited/enrolled18-125 YearsNIDDKCongenital
000460-IA Randomized, Placebo-controlled Crossover Study to Assess the Safety of Administering a Second Dose of a COVID-19 mRNA Vaccine in Individuals Who Experienced a Systemic Allergic Reaction to an Initial DoseCompleted Study; data analyses ongoing16-69 YearsNIAID16
000406-AAAddictions Neuroclinical AssessmentEnrolling by Invitation18-125 YearsNIAAA16
000310-CHA Phase 1/2, First-in-Human, Open-Label, Dose-Escalation Study of the Safety and Efficacy of Gene Therapy for Congenital Adrenal Hyperplasia through Administration of an Adeno-Associated Virus (AAV) Serotype 5-Based Recombinant Vector Encoding the Human Recruitment has not started18-125 YearsNICHDCongenital
000297-CHA Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Crinecerfont (NBI-74788) in Adult Subjects with Classic Congenital Adrenal Hyperplasia, Followed by Open-Label TreatmentParticipants currently recruited/enrolled18-125 YearsNICHDCongenital
000277-CImaging and Biopsy of HIV-Infected Individuals Undergoing Analytic Treatment InterruptionParticipants currently recruited/enrolled18-125 YearsNCI 16
000241-CHPhase II Trial of Liraglutide (Saxenda(R), Novo Nordisk) in Adolescents with Obesity After Sleeve Gastrectomy: A Pilot Open-Label StudyParticipants currently recruited/enrolled12-20 YearsNICHD16
000236-IA Phase 1 Study of Empagliflozin as Treatment for Severe Congenital Neutropenia Due to G6PC3 DeficiencyParticipants currently recruited/enrolled18-125 YearsNIAIDCongenital
000183-IAn open-label single-arm Phase IIb study of F901318 as treatment of invasive fungal infections due to Lomentospora prolificans, Scedosporium spp., Aspergillus spp., and other resistant fungi in patients lacking suitable alternative treatment optionsParticipants currently recruited/enrolled16-125 YearsNIAID16
000123-CCEvaluation of Atherosclerotic Plaques in Abdominal CT StudiesNo longer recruiting/follow-up only0-125 YearsCC 16
000115-CA Trial of the Safety and Immunogenicity of the COVID-19 Vaccine (mRNA-1273) in Participants with Hematologic Malignancies and Various Regimens of Immunosuppression, and in Participants with Solid Tumors on PD1/PDL1 Inhibitor Therapy, Including Booster DParticipants currently recruited/enrolled18-125 YearsNCI 16
20-M-0157PET Imaging of Cyclooxygenase in Participants with Major Depressive Disorder (MDD)Participants currently recruited/enrolled18-70 YearsNIMH 16
20-H-0141Long-term Follow-up of Subjects With Sickle Cell Disease Treated With Ex Vivo Gene Therapy Using Autologous Hematopoietic Stem Cells Transduced With a Lentiviral VectorEnrolling by Invitation18-125 YearsNHLBI16
20-DK-0079A Randomized, Double-Blinded, Placebo-Controlled Study of REGN4661, A Leptin Receptor Agonist Antibody, In Patients with Generalized LipodystrophyNo longer recruiting/follow-up only12-125 YearsNIDDK16
20-D-0131Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sj(SqrRoot)(Delta)gren's Syndrome; a Phase Ib-IIa Placebo-controlled Clinical Trial and Associated Mechanistic StudiesParticipants currently recruited/enrolled18-75 YearsNIDCR16
20-D-0122A Phase IIb, Open-label Dose-ranging Study Evaluating the Safety, Tolerability, Pharmacodynamics and Pharmacokinetics, and Efficacy of CLTX-305 (encaleret) in Autosomal Dominant Hypocalcemia Type 1 (ADH1)No longer recruiting/follow-up only16-125 YearsNIDCR16
20-CH-0126Data Collection Study of Pediatric and Adolescent Gynecology ConditionsParticipants currently recruited/enrolled0-125 YearsNICHDCongenital
20-C-0098A Phase 1/2, Open Label, Dose-Escalation, Safety and Tolerability Study of NC410 in Subjects with Advanced or Metastatic Solid TumorsCompleted Study; data analyses ongoing18-125 YearsNCI 16
20-C-0070A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Patients with Inborn Errors of ImmunityParticipants currently recruited/enrolled4-69 YearsNCI Congenital
20-C-0069A First-In-Human Phase I Single-Agent Dose-Escalation, Food Effect and Dose Expansion Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System NeoplasmsParticipants currently recruited/enrolled18-125 YearsNCI 16
20-C-0062A phase 1b Study of Nivolumab in Patients with Autoimmune Disorders and Advanced Malignancies (AIM-NIVO)Participants currently recruited/enrolled18-125 YearsNCI 16
19-I-0140A Phase 1 Evaluation of the Safety of Belimumab in People with Idiopathic CD4 Lymphopenia and Autoantibodies (Phoebe)Participants currently recruited/enrolled18-70 YearsNIAID16
19-DK-0072Non-Alcoholic Fatty Liver Disease, the Hepatic Response to Oral Glucose, and the Effect of Semaglutide (NAFLD HEROES)Participants currently recruited/enrolled18-125 YearsNIDDK16
19-CH-0020A Phase 1-2 Multi-Center Study to Assess the Efficacy and Safety of Abiraterone Acetate as Adjunctive Therapy in Pre-Pubescent Children with Classic 21-Hydroxylase DeficiencyRecruitment has not started2-9 YearsNICHDCongenital
19-C-0085Phase II Trial of Allogeneic Hematopoietic Cell Transplantation for Peripheral T cell LymphomaClinical hold/Recruitment or enrollment suspended12-125 YearsNCI Congenital
19-C-0016Natural History and Biospecimen Acquisition Study for Children and Adults with Rare Solid TumorsParticipants currently recruited/enrolled0-125 YearsNCI 16
19-C-0006Phase II Trial Evaluating Nivolumab In Patients With IDH-Mutant Gliomas With And Without Hypermutator PhenotypeParticipants currently recruited/enrolled18-125 YearsNCI 16
19-AT-0089Sensory Afferents for Deep Pressure SensationCompleted Study; data analyses ongoing18-50 YearsNCCIH16
18-N-0083ASPIRO: A Phase 1/2/3, Randomized, Open-Label, Ascending-Dose, Delayed-Treatment Concurrent Control Clinical Study to Evaluate the Safety and Efficacy of AT132, an AAV8-Delivered Gene Therapy in X-Linked Myotubular Myopathy (XLMTM) PatientsNo longer recruiting/follow-up only3-5 YearsNINDS16
18-EI-0068An Investigation of Vitamin A Palmitate Supplementation in Patients with Reticular Pseudodrusen (RPD) and Delayed Dark AdaptationParticipants currently recruited/enrolled50-125 YearsNEI 16
18-EI-0067An Investigation of Vitamin A Palmitate Supplementation in Patients with Age-Related Macular Degeneration (and without reticular pseudodrusen) and Delayed Dark AdaptationParticipants currently recruited/enrolled50-125 YearsNEI 16
18-DA-N095Just-In-Time Adaptive Interventions for Addictive BehaviorsParticipants currently recruited/enrolled18-75 YearsNIDA 16
18-DA-N053Imaging Biomarker for Addiction Treatment OutcomeParticipants currently recruited/enrolled21-125 YearsNIDA 16
18-C-0135Phase II Trial of Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or DysregulationParticipants currently recruited/enrolled4-125 YearsNCI Congenital
18-C-0080Feasibility and Preliminary Efficacy of an Enhanced Mindfulness Intervention for Children and Young Adults with High Grade or High-Risk Cancer and Their Caregivers: A Pilot Randomized Controlled TrialCompleted Study; data analyses ongoing5-125 YearsNCI 16
17-H-0095Heart Catheterization Using Magnetic Resonance Imaging (MRI) Fluoroscopy and Passive GuidewiresParticipants currently recruited/enrolled18-125 YearsNHLBICongenital
16-N-0170Effects of Prism Adaption and rTMS on Brain Connectivity and Visual RepresentationCompleted Study; data analyses ongoing18-75 YearsNINDS16
16-N-0166Deep Brain Stimulation Surgery for Treatment of Focal Hand DystoniaParticipants currently recruited/enrolled22-125 YearsNINDS16
16-N-0114The Effect of Corticosteroids on Inflammation at the Edge of Acute Multiple Sclerosis Plaques: An Investigator-Blinded StudyParticipants currently recruited/enrolled18-125 YearsNINDS16
16-N-0072A Pilot Study of Adoptive Cellular Immunotherapy for Progressive Multifocal Leukoencephalopathy with Ex Vivo Generated Polyomavirus-Specific T-cellsCompleted Study; data analyses ongoing18-125 YearsNINDS16
16-N-0064Cholinergic Receptor Imaging in DystoniaCompleted Study; data analyses ongoing18-125 YearsNINDS16
16-N-0058Myalgic Encephalomyelitis/Chronic Fatigue SyndromeCompleted Study; data analyses ongoing18-60 YearsNINDS16
16-N-0055The Pathological Basis of MRI Signal Changes in Multiple Sclerosis: A Longitudinal In Vivo-to-Postmortem StudyParticipants currently recruited/enrolled18-125 YearsNINDS16
16-N-0041Tumor Related EpilepsyParticipants currently recruited/enrolled8-125 YearsNINDS16
16-N-0031An All-Night Functional Magnetic Resonance Imaging Sleep Study With Auditory StimuliParticipants currently recruited/enrolled18-34 YearsNINDS16
16-I-0165An open-label, non-randomized extension study to evaluate the long term safety, tolerability, efficacy and pharmacokinetics of CDZ173 (leniolisib) in patients with APDS/PASLI (Activated phosphoinositide 3-kinase delta syndrome/p110 delta-activating mutatNo longer recruiting/follow-up only12-75 YearsNIAID16
16-I-0126Genomic Response of Human Immune and Non-Immune Cells to GlucocorticoidsCompleted Study; data analyses ongoing18-64 YearsNIAID16
16-I-0078Microbial, Immune, and Metabolic Perturbations by Antibiotics (MIME study)Participants currently recruited/enrolled18-49 YearsNIAID16
16-I-0065Screening for Alpha Globin DeletionsParticipants currently recruited/enrolled18-39 YearsNIAID16
16-I-0053A Multicenter Study of the Immunogenicity of Recombinant Vesicular Stomatitis Vaccine for Ebola-Zaire (rVSVdeltaG-ZEBOV GP) for Pre-Exposure Prophylaxis in Individuals at Potential Occupational Risk for Ebola Virus Exposure (PREPARE)No longer recruiting/follow-up only18-125 YearsNIAID16
16-I-0039Screening of Healthy Volunteers for Investigational Antimalarial Drugs, Malaria Vaccines, and Controlled Human Malaria ChallengeParticipants currently recruited/enrolled18-50 YearsNIAID16
16-I-0032High Dose Peripheral Blood Stem Cell Transplantation with Post Transplant Cyclophosphamide for Patients with Chronic Granulomatous DiseaseNo longer recruiting/follow-up only4-65 YearsNIAID16
16-HG-0156The Natural History, Physiology, Microbiome and Biochemistry Studies of Propionic AcidemiaParticipants currently recruited/enrolled0-125 YearsNHGRI16
16-HG-0026New Technology and Child HealthParticipants currently recruited/enrolled18-125 YearsNHGRI16
16-HG-0017Genomic Services Research ProgramParticipants currently recruited/enrolled0-125 YearsNHGRI16
16-H-0144Impact of Elastin Mediated Vascular Stiffness on End OrgansParticipants currently recruited/enrolled3-85 YearsNHLBI16
16-H-0132CADASIL Disease DiscoveryCompleted Study; data analyses ongoing18-100 YearsNHLBI16
16-H-0129Study to Evaluate the Effect of Nicotinamide Riboside on ImmunityCompleted Study; data analyses ongoing18-39 YearsNHLBI16
16-H-0085Pilot Study to Evaluate the Effect of Fasting and Refeeding on T-Cell FateCompleted Study; data analyses ongoing21-37 YearsNHLBI16
16-H-0074Williams Syndrome (WS) and Supravalvular Aortic Stenosis (SVAS) DNA and Tissue BankParticipants currently recruited/enrolled0-85 YearsNHLBI16
16-H-0063Williams Syndrome Skin and Vascular Elasticity Study (WS-SAVE Study)Completed Study; data analyses ongoing1-70 YearsNHLBI16
16-H-0019High Image Matrix CT ReconstructionCompleted Study; data analyses ongoing18-99 YearsNHLBI16
16-EI-0169A Pilot Study to Investigate Ustekinumab (STELARA) for the Treatment of Active Sight-Threatening UveitisCompleted Study; data analyses ongoing18-125 YearsNEI 16
16-EI-0134Studies of the Natural History, Pathogenesis and Outcome of Ocular DisordersParticipants currently recruited/enrolled0-125 YearsNEI 16
16-EI-0104Clinical and Molecular Studies in Families with Inherited Eye DiseaseParticipants currently recruited/enrolled4-125 YearsNEI 16
16-EI-0090Natural History of Spinocerebellar Ataxia Type 7 (SCA7)Participants currently recruited/enrolled12-125 YearsNEI 16
16-EI-0046Uveitis/Intraocular Inflammatory Disease Biobank (iBank)No longer recruiting/follow-up only8-125 YearsNEI 16
16-EI-0024Rod and Cone Mediated Function in Retinal DiseaseParticipants currently recruited/enrolled5-125 YearsNEI 16
16-E-0157CaREFREE Study (Calorie Restriction, Environment and Fitness: Reproductive Effects Evaluation Study)Completed Study; data analyses ongoing18-28 YearsNIEHS16
16-E-0096Cytochrome P450 Epoxygenase Pathway Regulation of Macrophage FunctionParticipants currently recruited/enrolled18-65 YearsNIEHS16
16-E-0006Investigating the Impact of Obesity on Pubertal Development in GirlsParticipants currently recruited/enrolled8-14 YearsNIEHS16
16-DK-0173MEASuRE: Metreleptin Effectiveness and Safety RegistryParticipants currently recruited/enrolled0-125 YearsNIDDK16
16-DK-0143Idiosyncratic Liver Injury Associated with Drugs (ILIAD): A Retrospective StudyParticipants currently recruited/enrolled18-125 YearsNIDDK16
16-DK-0125Evaluation of Adults with Endocrine-Related ConditionsParticipants currently recruited/enrolled18-100 YearsNIDDK16
16-DK-0068The Molecular, Cellular, and Genetic Characterization of Human Adipose Tissue and its Role in MetabolismParticipants currently recruited/enrolled18-125 YearsNIDDK16
16-DK-0038A Randomized, Double Blind, Placebo-Controlled Study to Assess Efficacy, Safety and Tolerability of ISIS 304801 in Patients with Partial Lipodystrophy with an Open-Label ExtensionCompleted Study; data analyses ongoing18-125 YearsNIDDK16
16-DA-N140Effects of a New Behavioral Intervention on Alcohol Craving and DrinkingParticipants currently recruited/enrolled21-65 YearsNIDA 16
16-DA-0080A Novel Compound for Alcoholism Treatment: a Translational Strategy - Part IICompleted Study; data analyses ongoing18-70 YearsNIDA 16
16-D-0040Natural History of Craniofacial Anomalies and Developmental Growth VariantsParticipants currently recruited/enrolled2-125 YearsNIDCR16
16-CH-0113Evaluation of Children with Endocrine and Metabolic-Related ConditionsParticipants currently recruited/enrolled0-100 YearsNICHD16
16-CH-0103Evaluation of Patients with Genetic DisordersParticipants currently recruited/enrolled0-125 YearsNICHD16
16-CC-0168Focus Groups to Determine Surrogates' Views Regarding Patient Preference PredictorsCompleted Study; data analyses ongoing18-90 YearsCC 16
16-CC-0162Longitudinal Changes in the Oral and Gut Microbiome of Individuals with Alcohol DependenceCompleted Study; data analyses ongoing18-125 YearsCC 16
16-CC-0149Dopamine and Motor Learning in Cerebral PalsyParticipants currently recruited/enrolled5-25 YearsCC 16
16-CC-0112Impact of Once-Weekly Rifapentine and Isoniazid on the Steady State Pharmacokinetics of Dolutegravir and Darunavir Boosted with Cobicistat in Healthy VolunteersCompleted Study; data analyses ongoing18-65 YearsCC 16
16-CC-0098Pilot Study of Ultrasound Guided Focal Thermal Ablation of Prostate CancerClinical hold/Recruitment or enrollment suspended18-125 YearsCC 16
16-CC-0056Analysis of A Tool to Assess Psycho Social Spiritual Healing: Cognitive InterviewingCompleted Study; data analyses ongoing18-125 YearsCC 16
16-CC-0049A Phase II Study Using LC Bead LUMI Radio-Opaque Embolic Beads to Detect and Characterize the Vascularity of Hepatic Tumors During Treatment with Transarterial Embolization (TAE) Alone or Combined with Thermal AblationEnrolling by Invitation18-125 YearsCC 16
16-CC-0001Evaluation of MiSeq for Microbial Identification in SpecimensEnrolling by Invitation2-125 YearsCC 16
16-C-0171Phase I/II Study of Lenalidomide Combined with Modified DA-EPOCH and Rituximab (EPOCH-R2) in Primary Effusion Lymphoma or KSHV-Associated Large Cell LymphomaParticipants currently recruited/enrolled18-125 YearsNCI 16
16-C-0154A Phase I/II Trial of T Cell Receptor Gene Therapy Targeting HPV-16 E7 for HPV-Associated CancersParticipants currently recruited/enrolled18-125 YearsNCI 16
16-C-0151Evaluation of the Natural History of and Specimen Banking for Patients with Tumors of the Central Nervous SystemParticipants currently recruited/enrolled18-125 YearsNCI 16
16-C-0138Collection of Peripheral Blood Mononuclear Cells (PBMCs) from Healthy Subjects for the Expansion of T Cells for Adoptive Cell TherapyParticipants currently recruited/enrolled18-99 YearsNCI 16
16-C-0135A Pilot Study of Combined Immune Checkpoint Inhibition in combination with Ablative Therapies in Subjects with Hepatocellular Carcinoma (HCC) or Biliary Tract Carcinomas (BTC)No longer recruiting/follow-up only18-125 YearsNCI 16
16-C-0131A Phase I/II Study Administering Peripheral Blood Lymphocytes Transduced with a CD70-Binding Chimeric Antigen Receptor to Patients with CD70-Expressing CancersParticipants currently recruited/enrolled18-70 YearsNCI 16
16-C-0128A Phase I/II Study of Mesothelin-Targeted Immunotoxin LMB-100 Alone or in Combination with Nab-Paclitaxel in Participants with Previously Treated Metastatic and/ or Locally Advanced Pancreatic Ductal Adenocarcinoma and Mesothelin Expressing Solid TumorsCompleted Study; data analyses ongoing18-125 YearsNCI 16
16-C-0121A Pilot Clinical Trial of Genomic Based Assignment of Therapy in Advanced Urothelial CarcinomaCompleted Study; data analyses ongoing18-125 YearsNCI 16
16-C-0107A Phase I/II Trial of EP0057, a Nanoparticle Camptothecin with Olaparib in Patients with Relapsed/Refractory Small Cell Lung, Bladder and Prostate CancersParticipants currently recruited/enrolled18-125 YearsNCI 16
16-C-0097Phase 1 Trial of Panobinostat in Children with Diffuse Intrinsic Pontine GliomaCompleted Study; data analyses ongoing2-21 YearsNCI 16
16-C-0094A Phase 1/2 Study of Baricitinib, a JAK1/2 Inhibitor, in Chronic Graft-Versus-Host Disease (cGVHD) after Allogeneic Hematopoietic Stem Cell Transplantation (SCT)No longer recruiting/follow-up only18-125 YearsNCI 16
16-C-0092A Pilot Study of Local Ablative Therapy for Treatment of Oligoprogressive, EGFR-mutated, Non-Small Cell Lung Cancer (NSCLC) After Treatment with Osimertinib (AZD9291, Tagrisso)Completed Study; data analyses ongoing18-125 YearsNCI 16
16-C-0088A Randomized Phase II/III Study of the Combination of Cediranib and Olaparib Compared to Cediranib or Olaparib Alone, or Standard of Care Chemotherapy in Women with Recurrent Platinum-Resistant or -Refractory Ovarian, Fallopian Tube, or Primary PeritoneaCompleted Study; data analyses ongoing18-125 YearsNCI 16
16-C-0087Phase I Study of Veliparib (ABT-888), an Oral PARP Inhibitor, and VX-970, an ATR Inhibitor in Combination with Cisplatin in Patients with Refractory Solid TumorsCompleted Study; data analyses ongoing18-125 YearsNCI 16
16-C-0081A Phase I Dose Escalation Trial of Re-Irradiation in Good Prognosis Recurrent GlioblastomaNo longer recruiting/follow-up only18-125 YearsNCI 16
16-C-0076Prospective Screening for Patient Specific Genotypes and Phenotypes that Influence Drug Dosing and Trial Selection in Cancer PatientsEnrolling by Invitation18-125 YearsNCI 16
16-C-0073A Phase 2 Study of Olaparib and Cediranib for the Treatment of Recurrent Ovarian CancerCompleted Study; data analyses ongoing18-125 YearsNCI 16
16-C-0066Phase I Study of MK-3475 (Pembrolizumab) in Patients with Human Immunodeficiency Virus (HIV) and Relapsed/Refractory or Disseminated Malignant NeoplasmParticipants currently recruited/enrolled18-125 YearsNCI 16
16-C-0062A Phase I Study of Subcutaneous Recombinant Human IL-15 (S.C. Rhil-15) and Alemtuzumab for Patients with Refractory or Relapsed Chronic and Acute Adult T-Cell Leukemia (ATL)Completed Study; data analyses ongoing18-125 YearsNCI 16
16-C-0061Biospecimen Procurement for Center for Immuno-Oncology Immunotherapy ProtocolsParticipants currently recruited/enrolled18-125 YearsNCI 16
16-C-0060A Phase 1b/2 Study of alvelestat (MPH966), an Oral Neutrophil Elastase Inhibitor, in Bronchiolitis Obliterans Syndrome after Allogeneic Hematopoietic Stem Cell TransplantationParticipants currently recruited/enrolled18-125 YearsNCI 16
16-C-0054T Cells Expressing a Fully-human Anti- CD19 Chimeric Antigen Receptor for Treating B-cell MalignanciesNo longer recruiting/follow-up only18-73 YearsNCI 16
16-C-0048Docetaxel and Prostvac for Metastatic Castration Sensitive Prostate CancerNo longer recruiting/follow-up only18-125 YearsNCI 16
16-C-0047A Phase 1 Trial of Pomalidomide in Combination with Liposomal Doxorubicin in Patients with Advanced or Refractory Kaposi SarcomaParticipants currently recruited/enrolled18-125 YearsNCI 16
16-C-0043Phase II Trial of the MEK1/2 Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate in Adults with Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform NeurofibromasNo longer recruiting/follow-up only18-125 YearsNCI 16
16-C-0035Prostvac in Patients with Biochemically Recurrent Prostate CancerNo longer recruiting/follow-up only18-125 YearsNCI 16
16-C-0034A Phase II Trial of Oral Pazopanib plus Oral Topotecan Metronomic Antiangiogenic Therapy for Recurrent Glioblastoma Multiforme (A) without Prior Bevacizumab Exposure and (B) after Failing Prior BevacizumabCompleted Study; data analyses ongoing18-125 YearsNCI 16
16-C-0027A Prospective Randomized and Phase II Trial for Metastatic Melanoma Using Adoptive Cell Therapy with Tumor-Infiltrating Lymphocytes Plus IL-2 Either Alone or Following the Administration of PembrolizumabParticipants currently recruited/enrolled18-70 YearsNCI 16
16-C-0011A Phase I-II Trial of Everolimus and Sorafenib in Patients with Recurrent High-Grade GliomasCompleted Study; data analyses ongoing18-125 YearsNCI 16
16-C-0010Care of the Prostate Cancer Patient and Prospective Procurement of Prostate Cancer TissueParticipants currently recruited/enrolled18-125 YearsNCI 16
16-C-0009Phase II Trial of Carboplatin and Bevacizumab for the Treatment of Recurrent Low-Grade and Anaplastic Supratentorial, Infratentorial and Spinal Cord Ependymoma in Adults: A Multi-Center TrialCompleted Study; data analyses ongoing18-125 YearsNCI 16
16-AT-0136Effects of External Ear Stimulation on Pain Perception and MoodParticipants currently recruited/enrolled18-50 YearsNCCIH16
16-AT-0077Clinical and Scientific Assessment of Pain and Painful DisordersParticipants currently recruited/enrolled12-125 YearsNCCIH16
16-AA-0059Characterization of Brain Amyloid-beta (A-beta) Retention During Wakefulness And Following Emergence From Sleep In Healthy SubjectsCompleted Study; data analyses ongoing18-40 YearsNIAAA16
16-AA-0037Effect of Opioid Receptor Modulation on Alcohol Self-Administration and Neural Response to Alcohol Cues in Heavy Drinkers: Role of OPRM1 Gene VariationParticipants currently recruited/enrolled21-60 YearsNIAAA16
15-I-0135An open-label, non-randomized, within-patient dose-finding study followed by a randomized, subject, investigator and sponsor-blinded placebo controlled study to assess the efficacy and safety of CDZ173 (leniolisib) in patients with APDS/PASLI (Activated Completed Study; data analyses ongoing12-75 YearsNIAID16
15-DK-0108Natural History of Noncirrhotic Portal HypertensionParticipants currently recruited/enrolled12-125 YearsNIDDKCongenital
15-C-0142Acceptance and Commitment Training for Adolescents and Adults with Neurofibromatosis Type 1, Plexiform Neurofibromas, and Chronic Pain: A Phase III Clinical TrialCompleted Study; data analyses ongoing16-59 YearsNCI 16
15-C-0138Phase I Study of Ipilimumab, Nivolumab, and the Combination in Patients with Newly Diagnosed GlioblastomaCompleted Study; data analyses ongoing18-125 YearsNCI 16
15-C-0078Safety and Feasibility of Stem Cell Gene Transfer Following R-EPOCH for Non-Hodgkin Lymphoma in AIDS Patients Using Peripheral Blood Stem/Progenitor Cells Treated with a Lentivirus Vector-Encoding Multiple Anti-HIV RNAsNo longer recruiting/follow-up only18-65 YearsNCI 16
14-HG-0071Clinical and Basic Investigations into Known and Suspected Congenital Disorders of GlycosylationParticipants currently recruited/enrolled1-80 YearsNHGRICongenital
14-HG-0055Study on Moebius Syndrome and Other Congenital Facial Weakness DisordersCompleted Study; data analyses ongoing2-80 YearsNHGRICongenital
13-DK-0091Combination Therapy of Pegylated Interferon Alfa-2a and Tenofovir DF versus Tenofovir DF Monotherapy in HBeAg-Positive and HBeAg-Negative Chronic Hepatitis BCompleted Study; data analyses ongoing18-125 YearsNIDDK16
13-D-0033Diagnosis and Treatment of Patients in Need of Third Molar Removal and Oral Specimen AcquisitionParticipants currently recruited/enrolled16-50 YearsNIDCR16
13-C-0016A Phase I Study of an Adenoviral Transduced Autologous Dendritic Cell Vaccine Expressing Human HER2/neu ECTM in Adults with Tumors with 1-3+ HER2/neu ExpressionCompleted Study; data analyses ongoing18-125 YearsNCI 16
11-I-0057Effect of Interferon Alpha 2b Intensification on HIV-1 Residual Viremia in Individuals Suppressed on Antiretroviral TherapyCompleted Study; data analyses ongoing18-65 YearsNIAID16
11-H-0134A Pilot Study of a Thrombopoietin-Receptor Agonist (TPO-R Agonist), Eltrombopag, in Moderate Aplastic Anemia PatientsNo longer recruiting/follow-up only2-125 YearsNHLBI16
11-D-0172The Pathogenesis and Natural History of Sjogren's SyndromeParticipants currently recruited/enrolled16-125 YearsNIDCR16
11-C-0200A Phase II Trial In Which Patients With Metastatic Alveolar Soft Part Sarcoma Are Randomized to Either Sunitinib or Cediranib Monotherapy, with Cross-Over at Disease ProgressionNo longer recruiting/follow-up only16-125 YearsNCI 16
10-HG-0065Whole Genome Medical Sequencing for Gene DiscoveryParticipants currently recruited/enrolled0-125 YearsNHGRICongenital
09-I-0184Studies in the Pathogenesis of Systemic Capillary Leak SyndromeParticipants currently recruited/enrolled0-125 YearsNIAID16
09-H-0225Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Severe Congenital Anemias Including Sickle Cell Disease and Beta-ThalassemiaNo longer recruiting/follow-up only2-125 YearsNHLBICongenital
09-H-0199A Pilot Study of a Thrombopoietin-Receptor Agonist (TPO-R agonist), Eltrombopag, in Patients with Low to Int-2 Risk Myelodysplastic Syndrome (MDS)Completed Study; data analyses ongoing18-125 YearsNHLBI16
09-C-0024A Phase I Study of Quadrivalent Human Papilloma Virus (HPV) (Types 6, 11, 16, 18) Recombinant Vaccine in HIV-Infected and HIV-Negative Pre-Adolescents, Adolescents and Young AdultsCompleted Study; data analyses ongoing12-26 YearsNCI 16
08-C-0130A Phase II Trial of Peginterferon alfa-2b (PEG-Intron) for Neurofibromatosis Type 1 Related Unresectable, Symptomatic or Life-Threatening Plexiform NeurofibromasCompleted Study; data analyses ongoing0-21 YearsNCI Congenital
07-E-0012Rituximab in the Treatment of Refractory Adult and Juvenile Dermatomyositis (DM) and Adult Polymyositis (PM)Completed Study; data analyses ongoing2-125 YearsNIEHS16
06-CH-0011Natural History Study of Patients with Excess AndrogenParticipants currently recruited/enrolled0-99 YearsNICHDCongenital
04-AR-0205Progression of Spinal Fusion in Ankylosing SpondylitisCompleted Study; data analyses ongoing18-125 YearsNIAMS16
03-AR-0131Genetic Determinants of Ankylosing Spondylitis Severity - Longitudinal StudyCompleted Study; data analyses ongoing18-125 YearsNIAMS16
02-C-0052Etiologic Investigation of Cancer Susceptibility in Inherited Bone Marrow Failure Syndromes: A Natural History StudyParticipants currently recruited/enrolled0-125 YearsNCI Congenital
96-CH-0033An Open, Randomized, Long-Term Clinical Trial of Flutamide, Testolactone, and Reduced Hydrocortisone Dose vs. Conventional Treatment of Children with Congenital Adrenal HyperplasiaNo longer recruiting/follow-up only2-18 YearsNICHDCongenital
94-HG-0132The Phenotype and Etiology of Proteus SyndromeParticipants currently recruited/enrolled0-125 YearsNHGRICongenital
94-C-0074Treatment and Natural History Study of Lymphomatoid GranulomatosisParticipants currently recruited/enrolled12-125 YearsNCI 16
91-AR-0196Studies on the Natural History and Pathogenesis of Polymyositis, Dermatomyositis, and Related DiseasesParticipants currently recruited/enrolled16-125 YearsNIAMS16
89-M-0006Brain Imaging of Childhood Onset Psychiatric Disorders, Endocrine Disorders and Healthy VolunteersParticipants currently recruited/enrolled3-125 YearsNIMH Congenital
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