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224 Studies found from all possible combinations of your search terms. Select a protocol that you wish to review.
Protocol Number Title Protocol Status Min-Max Age Institute Keywords
17-C-0049A Phase I/II Trial of the Insulin-Like Growth Factor 1 Receptor (IGF-1R) Antibody AMG479 (Ganitumab) in Combination with the Src Family Kinase (SFK) Inhibitor Dasatinib in Patients with Embryonal and Alveolar RhabdomyosarcomaCompleted Study; data analyses ongoing2-125 YearsNCI Insulin-Like Growth Factor
000827-ARNatural History and Pathogenesis of Alopecia in Children and AdultsParticipants currently recruited/enrolled2-120 YearsNIAMSGrowth Factor
000798-DA Phase 2 Study of Burosumab for Fibroblast Growth Factor-23 Mediated Hypophosphatemia in Fibrous DysplasiaParticipants currently recruited/enrolled1-125 YearsNIDCRGrowth Factor
000475-CPhase 2 Study of Rogaratinib (BAY 1163877) in the Treatment of Patients with Sarcoma Harboring Alterations in Fibroblast Growth Factor Receptor (FGFR) 1-4 and SDH-deficient Gastrointestinal Stromal Tumor (GIST)Participants currently recruited/enrolled18-125 YearsNCI Growth Factor
000045-CA Phase I Trial of T Cell Receptor Gene Therapy Targeting KK-LC-1 for Gastric, Breast, Cervical, Lung and other KK-LC-1 Positive Epithelial CancersParticipants currently recruited/enrolled18-120 YearsNCI Growth Factor
21-C-0006Phase I/II Study Evaluating Safety and Efficacy of Tivozanib (AV-951) in CholangiocarcinomaClinical hold/Recruitment or enrollment suspended18-125 YearsNCI Growth Factor
20-C-0107Clinical, Genetic, and Epidemiologic Study of Children and Adults with RASopathiesParticipants currently recruited/enrolled0-125 YearsNCI Growth Factor
18-DK-N071Early Tracking of Childhood Health Determinants StudyParticipants currently recruited/enrolled0-125 YearsNIDDKGrowth Factor
18-C-0110Safety Run-In and Phase II Trial of M7824 and Topotecan or Temozolomide in Relapsed Small Cell CancersParticipants currently recruited/enrolled18-125 YearsNCI Growth Factor
15-CH-0096Children's Growth and Behavior StudyParticipants currently recruited/enrolled8-125 YearsNICHDGrowth Factor
14-DK-0195Acute Effects of Canagliflozin, a Sodium Glucose Co-Transporter 2 (SGLT2) Inhibitor on Bone Metabolism in Healthy VolunteersCompleted Study; data analyses ongoing18-125 YearsNIDDKGrowth Factor
14-C-0037A Phase 2 Study of the MET Kinase Inhibitor INC280 in Papillary Renal Cell CancerCompleted Study; data analyses ongoing18-125 YearsNCI Growth Factor
14-C-0001Phase II Study of Axitinib (AG-013736) with Evaluation of the VEGF-pathway in Metastatic, Recurrent or Primary Unresectable Pheochromocytoma/ParagangliomaCompleted Study; data analyses ongoing18-125 YearsNCI Growth Factor
13-C-0016A Phase I Study of an Adenoviral Transduced Autologous Dendritic Cell Vaccine Expressing Human HER2/neu ECTM in Adults with Tumors with 1-3+ HER2/neu ExpressionCompleted Study; data analyses ongoing18-125 YearsNCI Growth Factor
12-C-0047A Phase I/II Study of the Safety, Pharmacokinetics and Efficacy of Pomalidomide (CC-4047) in the Treatment of Kaposi Sarcoma in Individuals With or Without HIVCompleted Study; data analyses ongoing18-125 YearsNCI Growth Factor
11-M-0251A Longitudinal Investigation of the Endocrine and Neurobiologic Events Accompanying PubertyParticipants currently recruited/enrolled7-35 YearsNIMH Growth Factor
11-H-0046Cross-Sectional Characterization of Idiopathic BronchiectasisCompleted Study; data analyses ongoing18-125 YearsNHLBIGrowth Factor
11-E-0006The Role of TGF-Beta in Asthmatic Epithelial Cell Susceptibility to RSV InfectionCompleted Study; data analyses ongoing18-60 YearsNIEHSGrowth Factor
11-C-0096Pilot Trial of Molecular Profiling and Targeted Therapy for Advanced Non-Small Cell Lung Cancer, Small Cell Lung Cancer, and Thymic MalignanciesNo longer recruiting/follow-up only18-125 YearsNCI Growth Factor
09-I-0200A Phase I Study of MozobilTM in the Treatment of Patients with WHIMSParticipants currently recruited/enrolled18-75 YearsNIAIDGrowth Factor
09-C-0019A Phase I Study of Dasatinib in Combination with Bevacizumab in Advanced Solid TumorsCompleted Study; data analyses ongoing18-125 YearsNCI Growth Factor
06-H-0190Treatment of T-Large Granular Lymphocyte (T-LGL) Lymphoproliferative Disorders with Alemtuzumab (Campath)Completed Study; data analyses ongoing18-85 YearsNHLBIGrowth Factor
06-CH-0011Natural History Study of Patients with Excess AndrogenParticipants currently recruited/enrolled0-99 YearsNICHDGrowth Factor
05-H-0242A Pilot Study of Alemtuzumab (Campath) in Patients with Relapsed or Refractory Severe Aplastic AnemiaCompleted Study; data analyses ongoing2-110 YearsNHLBIGrowth Factor
04-C-0200Urinary and Serum VEGF and MMP Levels in Patients Receiving Radiation Therapy for Glioblastoma Multiforme: Prospective Determination of a Predictive Value for RecurrenceParticipants currently recruited/enrolled18-125 YearsNCI Growth Factor
03-C-0277Cell Harvest and Preparation for Surgery Branch Adoptive Cell Therapy ProtocolsEnrolling by Invitation18-125 YearsNCI Growth Factor
02-I-0286Efficacy of Tyrosine Kinase Inhibition in Reducing Eosinophilia in Patients with Myeloid and/or Steroid-Refractory Hypereosinophilic SyndromeParticipants currently recruited/enrolled2-125 YearsNIAIDGrowth Factor
02-I-0277Regulation of the Proliferation and Survival of Normal and Neoplastic Human Mast CellsParticipants currently recruited/enrolled0-80 YearsNIAIDGrowth Factor
00-N-0140A Prospective Natural History Study of VHL Patients with CNS HemangioblastomasNo longer recruiting/follow-up only8-75 YearsNINDSGrowth Factor
96-H-0049Use of Granulocyte Colony Stimulating Factor (G-CSF) Mobilized Leukapheresis Collections from Healthy Volunteers to Develop Improved Methods of Stem Cell and Lymphocyte Selection for Allogeneic TransplantationParticipants currently recruited/enrolled18-60 YearsNHLBIGrowth Factor
001572-CA Phase II Study of Bevacizumab in Adults with Recurrent Respiratory Papillomatosis (RRP)Recruitment has not started18-120 YearsNCI Growth
001516-CPhase I Study of Aerosolized Antibiotics and Pembrolizumab in Advanced Non-Small Cell Lung CancerRecruitment has not started10-120 YearsNCI Growth
001074-CHCharacterization of Dysmorphology in Subjects with Creatine Transporter DeficiencyParticipants currently recruited/enrolled2-40 YearsNICHDGrowth
000912-HGGenetic and Social Network Correlates of Rheumatoid Arthritis Outcomes in Hispanic Populations: A Prospective StudyParticipants currently recruited/enrolled18-125 YearsNHGRIFactor
000871-CCMediterranean-like Unprocessed (CLEAN-MED) Diet Intervention Study of the Gut Microbiome of Healthy AdultsParticipants currently recruited/enrolled18-60 YearsCC Factor
000780-DA Phase 2 Study of Denosumab for Prevention of Skeletal Disease Progression in Children with Fibrous DysplasiaParticipants currently recruited/enrolled4-14 YearsNIDCRGrowth
000756-DKPhase II Study of Growth Hormone Inhibition Using Pegvisomant In Severe Insulin ResistanceParticipants currently recruited/enrolled18-65 YearsNIDDKGrowth
000748-DKAnalysis of the Utility of Polygenic Scores for Prediction of Incident Type 2 Diabetes Across Multiple Ancestry GroupsNo longer recruiting/follow-up only0-125 YearsNIDDKFactor
000678-CRare Tumors and Cancer Predisposition in Individuals and FamiliesParticipants currently recruited/enrolled0-125 YearsNCI Factor
000577-HGGenomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African Americans Study (GENEFORECAST): Prospective COVID-19 Natural History StudyParticipants currently recruited/enrolled21-125 YearsNHGRIFactor
000545-DKPrevalence and Development of Liver Dysfunction in Hematopoietic Stem Cell Transplant: A Prospective Natural History StudyRecruitment has not started3-125 YearsNIDDKFactor
000518-CCObservational Study of Dietary Intake and Dietary Behaviors in Adults with Sickle Cell DiseaseParticipants currently recruited/enrolled18-125 YearsCC Factor
000479-HObservational Study to Deeply Phenotype Major Organs in Sickle Cell Disease After Curative TherapiesParticipants currently recruited/enrolled18-125 YearsNHLBIFactor
000441-EWomen's Health Awareness Community Resiliency, Environmental Action and Collaborations for Health (REACH) EquityParticipants currently recruited/enrolled18-125 YearsNIEHSFactor
000328-CBicalutamide Implants (Biolen ) with Radiation Therapy in Patients with Localized Prostate CancerParticipants currently recruited/enrolled18-125 YearsNCI Growth
000152-ENatural History of The Human Biological Response to Environmental Exposure and InjuryParticipants currently recruited/enrolled18-125 YearsNIEHSFactor
000123-CCEvaluation of Atherosclerotic Plaques in Abdominal CT StudiesNo longer recruiting/follow-up only0-125 YearsCC Factor
000070-HGGenomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African-Americans Study(GENE-FORECAST): Sodium Intervention Trial (SIT)/GENE-FORECAST SITParticipants currently recruited/enrolled21-125 YearsNHGRIFactor
21-I-0029Natural history, epidemiology and pathogenesis of severe HPV-related diseases (Neptune)Participants currently recruited/enrolled3-125 YearsNIAIDGrowth
21-C-0032GD2-CAR PERSIST: Production and Engineering of GD2-Targeted, Receptor Modified T Cells (GD2CART) for Osteosarcoma or Neuroblastoma to Increase Systemic Tumor ExposureParticipants currently recruited/enrolled0-35 YearsNCI Factor
20-HG-0120Acute Infection in Mitochondrial Disease: An Observational Prospective Natural History Study of Metabolism, Infection and Immunity During the COVID19 PandemicParticipants currently recruited/enrolled0-125 YearsNHGRIGrowth
20-CC-0036Exploring a Dietary Behavior Intervention in African-Americans at Risk for Cardiovascular Disease: A Community Acceptability and Feasibility StudyParticipants currently recruited/enrolled18-125 YearsCC Factor
20-C-0098A Phase 1/2, Open Label, Dose-Escalation, Safety and Tolerability Study of NC410 in Subjects with Advanced or Metastatic Solid TumorsCompleted Study; data analyses ongoing18-125 YearsNCI Growth
20-C-0076Phase 2 Trial of Encorafenib plus Binimetinib for Patients with BRAF V600 Mutated Relapsed/Refractory HCLParticipants currently recruited/enrolled18-125 YearsNCI Growth
20-C-0013Phase I/II Trial of PLX038 (PEGylated SN38) and Rucaparib in Solid Tumors and Small Cell CancersNo longer recruiting/follow-up only18-125 YearsNCI Growth
19-M-0054Mapping the Phenotype in Adults with Phelan-McDermid SyndromeCompleted Study; data analyses ongoing0-125 YearsNIMH Factor
19-I-0140A Phase 1 Evaluation of the Safety of Belimumab in People with Idiopathic CD4 Lymphopenia and Autoantibodies (Phoebe)Participants currently recruited/enrolled18-70 YearsNIAIDFactor
19-I-0084Skin Immunity Sample Collection Involving Blisters and BiopsiesRecruitment has not started7-65 YearsNIAIDFactor
19-HG-0092New Approaches for Empowering Studies of Asthma in Populations of African DescentCompleted Study; data analyses ongoing18-125 YearsNHGRIFactor
19-H-0120Pilot Study for Geospatial Analysis of Neighborhood Environmental Stress in Relation to Biological Markers of Cardiovascular Health and Health Behaviors in WomenParticipants currently recruited/enrolled19-45 YearsNHLBIFactor
19-CH-0071An Open-Label Phase 3 Study of the Safety and Efficacy of Pegvisomant in Children with Growth Hormone ExcessParticipants currently recruited/enrolled2-18 YearsNICHDGrowth
19-CC-0055Cardiovascular Disease in HIV and Hepatitis C: Risk Outcomes after Hepatitis C EradicationParticipants currently recruited/enrolled18-125 YearsCC Factor
19-C-0061A Phase 2 Trial of the MEK Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in Combination with the mTOR Inhibitor Sirolimus for Patients with Unresectable or Metastatic Malignant Peripheral Nerve Sheath TumorsParticipants currently recruited/enrolled12-125 YearsNCI Growth
19-C-0030A Phase 2 Study of Response-Adapted Therapy with Copanlisib and Rituximab in Untreated Follicular LymphomaParticipants currently recruited/enrolled18-125 YearsNCI Growth
19-C-0006Phase II Trial Evaluating Nivolumab In Patients With IDH-Mutant Gliomas With And Without Hypermutator PhenotypeParticipants currently recruited/enrolled18-125 YearsNCI Growth
18-H-0118Technical and Translational Development of Cardiovascular MRI (CMR)Participants currently recruited/enrolled7-125 YearsNHLBIFactor
18-EI-0055A Phase III Multicenter Randomized Sham Controlled Study to Determine the Safety and Efficacy of NT-501 in Macular Telangiectasia Type 2Completed Study; data analyses ongoing21-80 YearsNEI Factor
18-CH-0120A Natural History of the Collagen-Related Disorder Osteogenesis Imperfecta and the Genotype-Phenotype CorrelationNo longer recruiting/follow-up only0-125 YearsNICHDGrowth
18-C-0062Phase 2 Trial of XL184 (Cabozantinib) an Oral Small-Molecule Inhibitor of Multiple Kinases, in Children and Young Adults with Refractory Sarcomas, Wilms Tumor, and Other Rare TumorsCompleted Study; data analyses ongoing2-30 YearsNCI Growth
18-C-0017Profiling of Radiological Factors in Treatment and Outcomes in Prostate CancerParticipants currently recruited/enrolled18-125 YearsNCI Factor
18-C-0014Phase I Trial of 5-aza-4'-thio-2'-Deoxycytidine (Aza-TdC) in Patients with Advanced Solid TumorsParticipants currently recruited/enrolled18-120 YearsNCI Growth
18-AR-0081Investigation of the Natural History, Genetics, and Pathophysiology of Systemic Juvenile Idiopathic Arthritis, Adult-Onset Still's Disease and Related Inflammatory ConditionsParticipants currently recruited/enrolled0-125 YearsNIAMSFactor
17-N-0131Investigating Complex Neurodegenerative Disorders Related to Amyotrophic Lateral Sclerosis and Frontotemporal DementiaParticipants currently recruited/enrolled18-125 YearsNINDSFactor
17-H-0124Peripheral Blood Stem Cell Collection for Sickle Cell Disease (SCD) Patients Using PlerixaforCompleted Study; data analyses ongoing18-125 YearsNHLBIFactor
17-H-0118A Phase II Study Of Ibrutinib, Fludarabine, and Pembrolizumab in High-Risk or Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)No longer recruiting/follow-up only18-125 YearsNHLBIGrowth
17-H-0056Pathophysiology of Acute Pain in Patients with Sickle Cell DiseaseCompleted Study; data analyses ongoing18-80 YearsNHLBIFactor
17-DC-0138Observational Study of Hearing Loss and the Effects of Statin Drugs in Head and Neck Squamous Cell Carcinoma Patients Treated with Cisplatin ChemoradiationCompleted Study; data analyses ongoing18-125 YearsNIDCDFactor
17-C-0164A Phase 1b/2 Trial of Hu5F9-G4 in Combination with Rituximab or Rituximab + Chemotherapy in Patients with Relapsed/Refractory B-cell Non-Hodgkin's LymphomaNo longer recruiting/follow-up only18-125 YearsNCI Growth
17-C-0125Phase 2 Trial of Nivolumab in Epstein-Barr Virus (EBV)-Positive Lymphoproliferative Disorders and EBV-Positive Non-Hodgkin LymphomasParticipants currently recruited/enrolled12-125 YearsNCI Growth
17-C-0092A Phase I/II Study of Pexa-Vec Oncolytic Virus in Combination with Immune Checkpoint Inhibition in Refractory Colorectal CancerCompleted Study; data analyses ongoing18-125 YearsNCI Factor
17-C-0066A Pilot Study to Investigate the Safety and Clinical Activity of Avelumab (MSB0010718C) in Thymoma and Thymic Carcinoma after Progression on Platinum-Based ChemotherapyParticipants currently recruited/enrolled18-125 YearsNCI Growth
17-C-0011Phase 1 Study of Intraperitoneal Infusion of Autologous Monocytes with Sylatron (Peginterferon alfa-2b) and Actimmune (Interferon gamma-1b) in Women with Recurrent or Refractory Ovarian Cancer, Fallopian Tube Cancer or Primary Peritoneal CancerCompleted Study; data analyses ongoing18-125 YearsNCI Growth
17-AT-0155Sociocultural & Biobehavioral Influences on Pain Expression and AssessmentParticipants currently recruited/enrolled18-60 YearsNCCIHFactor
16-HG-0156The Natural History, Physiology, Microbiome and Biochemistry Studies of Propionic AcidemiaParticipants currently recruited/enrolled0-125 YearsNHGRIGrowth
16-EI-0046Uveitis/Intraocular Inflammatory Disease Biobank (iBank)No longer recruiting/follow-up only8-125 YearsNEI Factor
16-E-0157CaREFREE Study (Calorie Restriction, Environment and Fitness: Reproductive Effects Evaluation Study)Completed Study; data analyses ongoing18-28 YearsNIEHSFactor
16-E-0096Cytochrome P450 Epoxygenase Pathway Regulation of Macrophage FunctionParticipants currently recruited/enrolled18-65 YearsNIEHSFactor
16-D-0040Natural History of Craniofacial Anomalies and Developmental Growth VariantsParticipants currently recruited/enrolled2-125 YearsNIDCRGrowth
16-CH-0113Evaluation of Children with Endocrine and Metabolic-Related ConditionsParticipants currently recruited/enrolled0-100 YearsNICHDGrowth
16-C-0097Phase 1 Trial of Panobinostat in Children with Diffuse Intrinsic Pontine GliomaCompleted Study; data analyses ongoing2-21 YearsNCI Growth
16-C-0087Phase I Study of Veliparib (ABT-888), an Oral PARP Inhibitor, and VX-970, an ATR Inhibitor in Combination with Cisplatin in Patients with Refractory Solid TumorsCompleted Study; data analyses ongoing18-125 YearsNCI Growth
16-C-0043Phase II Trial of the MEK1/2 Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate in Adults with Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform NeurofibromasNo longer recruiting/follow-up only18-125 YearsNCI Growth
16-C-0035Prostvac in Patients with Biochemically Recurrent Prostate CancerNo longer recruiting/follow-up only18-125 YearsNCI Growth
15-M-0139Mapping the Genotype, Phenotype, and Natural History of Phelan McDermid SyndromeParticipants currently recruited/enrolled1-125 YearsNIMH Factor
15-HG-0049Maternal Inborn Errors of Metabolism in Pregnancy: A Pregnancy Registry ProtocolCompleted Study; data analyses ongoing14-50 YearsNHGRIGrowth
15-C-0145Phase I/II Study of the Anti-Programmed Death Ligand-1 Antibody Durvalumab (MEDI4736) in Combination with Olaparib and/or Cediranib for Advanced Solid Tumors and Advanced or Recurrent Ovarian, Triple Negative Breast, Lung, Prostate and Colorectal CancersParticipants currently recruited/enrolled18-125 YearsNCI Growth
15-C-0138Phase I Study of Ipilimumab, Nivolumab, and the Combination in Patients with Newly Diagnosed GlioblastomaCompleted Study; data analyses ongoing18-125 YearsNCI Growth
15-C-0116Phase I Trial of 4'-thio-2'-deoxycytidine (TdCyd) in Patients With Advanced Solid TumorsClinical hold/Recruitment or enrollment suspended18-125 YearsNCI Growth
15-C-0075A Randomized, Placebo-Controlled Phase II Study of Multi-Epitope TARP Peptide Autologous Dendritic Cell Vaccination in Men with Stage D0 Prostate CancerCompleted Study; data analyses ongoing18-125 YearsNCI Growth
15-AT-0132Neural and Psychological Mechanisms of Pain PerceptionParticipants currently recruited/enrolled18-50 YearsNCCIHFactor
14-I-0194Screening of Volunteers for Clinical Trials of Investigational or Licensed Vaccines or Antiviral ProductsParticipants currently recruited/enrolled18-65 YearsNIAIDFactor
14-I-0185A Phase III Double-Blind Randomized Crossover Study of Plerixafor Versus G-CSF in the Treatment of Patients with WHIM Syndrome.Completed Study; data analyses ongoing10-75 YearsNIAIDFactor
14-I-0020Hematopoietic Stem Cell Mobilization in Idiopathic CD4 Lymphocytopenia Patients and Healthy Controls for the Study of T Cell Maturation and Trafficking in Murine ModelsParticipants currently recruited/enrolled18-65 YearsNIAIDFactor
14-HG-0125Insights Into Microbiome and Environmental Contributions to Sickle Cell Disease and Leg UlcersParticipants currently recruited/enrolled18-125 YearsNHGRIFactor
14-HG-0048Genomics, Environmental Factors and Social Determinants of Cardiovascular Disease in African-Americans Study (GENE-FORECAST)Participants currently recruited/enrolled21-125 YearsNHGRIFactor
14-H-0127Characterization of the Pathogenesis of Primary and Secondary Lymphatic DisordersParticipants currently recruited/enrolled2-90 YearsNHLBIFactor
14-C-0131A Phase II, Open-Label Study in Patients With BRAF V600E-Mutated Rare Cancers With Several Histologies to Investigate the Clinical Efficacy and Safety of the Combination Therapy of Dabrafenib and TrametinibCompleted Study; data analyses ongoing18-125 YearsNCI Growth
13-H-0065Human Translational Studies of Inflammation and Cardiometabolic Diseases: The Psoriasis, Atherosclerosis and Cardiometabolic Disease (PACI) InitiativeNo longer recruiting/follow-up only18-125 YearsNHLBIFactor
13-E-0015Environmental Risk Factors for the Development of Myositis in Military PersonnelNo longer recruiting/follow-up only18-125 YearsNIEHSFactor
13-DK-0090Identifying Risk for Diabetes and Heart Disease in Women: A Study of African-American, African and White Federal Employees and ContractorsCompleted Study; data analyses ongoing25-65 YearsNIDDKFactor
13-C-0176Tumor, Normal Tissue and Specimens from Patients Undergoing Evaluation or Surgical Resection of Solid TumorsParticipants currently recruited/enrolled2-125 YearsNCI Growth
13-C-0153A Phase II Trial of Enzalutamide in Combination with PSA-TRICOM in Patients with Non-Metastatic Castration Sensitive Prostate CancerCompleted Study; data analyses ongoing18-125 YearsNCI Growth
13-C-0044A Phase 2 Study of Cabozantinib (XL184), a Dual Inhibitor of MET and VEGFR, in Patients With Metastatic Refractory Soft Tissue SarcomaNo longer recruiting/follow-up only18-120 YearsNCI Growth
13-AR-0056Stopping Tumor Necrosis Factor-Alpha Inhibitors in Rheumatoid ArthritisCompleted Study; data analyses ongoing18-125 YearsNIAMSFactor
12-N-0137A Phase 1 Open-Label Dose Escalation Safety Study of Convection Enhanced Delivery (CED) of Adeno-Associated Virus Encoding Glial Cell Line-Derived Neurotrophic Factor (AAV2-GDNF) in Subjects with Advanced Parkinson's Disease.Completed Study; data analyses ongoing18-125 YearsNINDSFactor
12-N-0122Integrating Genetic and Environmental Risk Scores into an Algorithm to Predict Multiple Sclerosis SusceptibilityCompleted Study; data analyses ongoing18-125 YearsNINDSFactor
12-HG-0202The Neurobehavioral, Environmental and Genetic Factors Impacting the Clinical Course of Attention Deficit Hyperactivity DisorderParticipants currently recruited/enrolled3-125 YearsNHGRIFactor
12-HG-0181The Clinical Study of Patients with Sex Chromosome VariantsCompleted Study; data analyses ongoing18-125 YearsNHGRIFactor
12-DA-N472Health Outcomes by Neighborhood - HON Study BaltimoreCompleted Study; data analyses ongoing18-100 YearsNIDA Factor
12-C-0205A Phase II Study of Cabozantinib (XL184) in Patients With Advanced/Metastatic Urothelial CarcinomaCompleted Study; data analyses ongoing18-125 YearsNCI Growth
12-C-0178Longitudinal Assessment and Natural History Study of Children and Adults with MEN2A or MEN2B with or without Medullary Thyroid CarcinomaParticipants currently recruited/enrolled0-125 YearsNCI Growth
12-C-0118A Phase II Study of Sunitinib in Patients with Advanced Relapsed or Refractory Thymoma or Thymic Carcinoma with at Least One Prior Line of Platinum-Based Systemic ChemotherapyNo longer recruiting/follow-up only18-100 YearsNCI Growth
12-C-0107Carfilzomib, Lenalidomide, and Dexamethasone in High-Risk Smoldering Multiple Myeloma: a Clinical and Correlative Pilot StudyNo longer recruiting/follow-up only18-125 YearsNCI Growth
12-C-0081Phase I/II Study of Cediranib and Olaparib in Combination for Treatment of Recurrent Papillary-Serous Ovarian, Fallopian Tube, or Peritoneal Cancer or for Treatment of Recurrent Triple-Negative Breast CancerNo longer recruiting/follow-up only18-125 YearsNCI Growth
12-C-0079A Phase II Multicenter Study of AMG 386 and Abiraterone in Metastatic Castration Resistant Prostate CancerCompleted Study; data analyses ongoing18-125 YearsNCI Growth
11-NR-0014Characterizing Fatigue Experienced by Cancer Patients Receiving Primary Treatment and Cancer SurvivorsParticipants currently recruited/enrolled18-125 YearsNINR Factor
11-I-0007Lentiviral Gene Transfer for Treatment of Children Older Than 2 Years of Age with X-Linked Severe Combined ImmunodeficiencyClinical hold/Recruitment or enrollment suspended2-40 YearsNIAIDGrowth
11-HG-0110Genetics of Obesity, Diabetes, and Heart Disease in African Diaspora PopulationsEnrolling by Invitation18-125 YearsNHGRIFactor
11-EI-0264A Pilot Study for the Evaluation of Minocycline as a Microglia Inhibitor in the Treatment of Central Retinal Vein OcclusionsCompleted Study; data analyses ongoing18-125 YearsNEI Growth
11-EI-0263A Pilot Study for the Evaluation of Minocycline as a Microglia Inhibitor in the Treatment of Branch Retinal Vein OcclusionsCompleted Study; data analyses ongoing18-125 YearsNEI Growth
11-E-0072Environmental Risk Factors for the Anti-Synthetase SyndromeParticipants currently recruited/enrolled2-100 YearsNIEHSFactor
11-DK-0108Observational Study of Persons with Hepatitis B Virus Infection in North America (Cohort Study)Completed Study; data analyses ongoing18-100 YearsNIDDKFactor
11-C-0255Clinical, Epidemiologic, and Genetic Studies of Li-Fraumeni SyndromeParticipants currently recruited/enrolled0-125 YearsNCI Factor
11-C-0161A Phase I/II Study of the Mitogen Activated Protein Kinase Kinase (MEK) 1 Inhibitor Selumetinib (AZD6244; Hydrogen Sulfate in Children with Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas (PN)No longer recruiting/follow-up only2-18 YearsNCI Growth
11-C-0140A Phase I Study of Gemcitabine, Carboplatin and Lenalidomide (GCL) for Treatment of Patients with Advanced/Metastatic Urothelial Carcinoma (UC) and Other Solid TumorsCompleted Study; data analyses ongoing18-125 YearsNCI Growth
11-C-0123A Prospective Randomized Study of Cell Transfer Therapy for Metastatic Melanoma Using Short-Term Cultured Tumor-Infiltrating Lymphocytes Plus IL-2 Following Either a Non-Myeloablative Lymphocyte Depleting Chemotherapy Regimen Alone or in Conjunction withNo longer recruiting/follow-up only18-66 YearsNCI Growth
11-C-0061Phase I Trial of Z-Endoxifen in Adults with Refractory Hormone Receptor-Positive Breast Cancer, Desmoid Tumors, Gynecologic Tumors, or other Hormone Receptor-Positive Solid TumorsNo longer recruiting/follow-up only18-125 YearsNCI Growth
11-AR-0223Studies on the Natural History and Pathogenesis of SpondyloarthritisParticipants currently recruited/enrolled2-125 YearsNIAMSGrowth
10-N-0143A Prospective Natural History Study of Patients with SyringomyeliaNo longer recruiting/follow-up only18-125 YearsNINDSFactor
10-I-0216Studies of Disorders with Increased Susceptibility to Fungal InfectionsParticipants currently recruited/enrolled0-125 YearsNIAIDFactor
10-H-0154Allogeneic Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia and Other Bone Marrow Failure Syndromes Using G-CSF Mobilized CD34+ Selected Hematopoietic Precursor Cells Co-Infused with a Reduced Dose of Non-Mobilized Donor T-CellsParticipants currently recruited/enrolled4-80 YearsNHLBIGrowth
10-H-0126Cardiovascular Disease Discovery ProtocolParticipants currently recruited/enrolled1-100 YearsNHLBIFactor
10-E-0134Effect of SNPs in p53 and p53 Response Elements on the Inflammatory Response to DNA DamageCompleted Study; data analyses ongoing18-100 YearsNIEHSFactor
10-E-0129Study of the Effect of Innate Immunity on the Inflammatory Response to EndotoxinParticipants currently recruited/enrolled18-125 YearsNIEHSFactor
10-DK-N091Molecular and Clinical Profile of Diabetes Mellitus and its ComplicationsParticipants currently recruited/enrolled18-125 YearsNIDDKFactor
10-CC-0115Imaging Techniques in MRIParticipants currently recruited/enrolled18-125 YearsCC Factor
10-C-0201Apheresis and CD34+ Selection of Mobilized Peripheral Blood CD34+ Cells from Patients with DOCK8 Deficiency, LAD-1, and GATA2 DeficiencyParticipants currently recruited/enrolled18-40 YearsNCI Factor
10-C-0054Administration of Anti-CD19-Chimeric-Antigen-Receptor-Transduced T Cells from the Original Transplant Donor to Patients with Recurrent or Persistent B-Cell Malignancies After Allogeneic Stem Cell TransplantationNo longer recruiting/follow-up only18-75 YearsNCI Growth
09-NR-0088Molecular-Genetic Correlates of Fatigue in Cancer Patients Receiving Localized External Beam Radiation TherapyCompleted Study; data analyses ongoing18-125 YearsNINR Factor
09-N-0010Biomarkers of Risk of Parkinson DiseaseCompleted Study; data analyses ongoing18-70 YearsNINDSFactor
09-I-0102Etiology, Pathogenesis, and Natural History of Idiopathic CD4+ LymphocytopeniaParticipants currently recruited/enrolled18-125 YearsNIAIDGrowth
09-I-0086Screening Protocol for Genetic Diseases of Allergic InflammationParticipants currently recruited/enrolled0-99 YearsNIAIDGrowth
09-H-0172Natural History of BronchiectasisParticipants currently recruited/enrolled5-125 YearsNHLBIFactor
09-C-0242Prospective Comprehensive Molecular Analysis of Endocrine NeoplasmsParticipants currently recruited/enrolled4-125 YearsNCI Growth
09-C-0192Phase II Study of Cediranib (AZD2171) in Patients With Alveolar Soft Part SarcomaNo longer recruiting/follow-up only0-125 YearsNCI Growth
09-C-0024A Phase I Study of Quadrivalent Human Papilloma Virus (HPV) (Types 6, 11, 16, 18) Recombinant Vaccine in HIV-Infected and HIV-Negative Pre-Adolescents, Adolescents and Young AdultsCompleted Study; data analyses ongoing12-26 YearsNCI Factor
08-N-0044A Prospective Natural History Study of Patients with Neurofibromatosis Type 2 (NF2).Participants currently recruited/enrolled8-75 YearsNINDSFactor
08-HG-0122Patient-Provider Communication and Interaction in a Virtual Clinical SettingCompleted Study; data analyses ongoing18-125 YearsNHGRIFactor
08-DK-0173A Trial of Segmental Stiffening Wires to Improve the Efficiency and Patient Tolerability of ColonoscopyCompleted Study; data analyses ongoing40-80 YearsNIDDKGrowth
08-DK-0149High Dose Ribavirin in Combination with Peginterferon for Patients with Chronic Hepatitis C Genotype 1 Infection Who Have Failed to Respond or Relapsed after Standard TherapyCompleted Study; data analyses ongoing18-65 YearsNIDDKFactor
08-C-0130A Phase II Trial of Peginterferon alfa-2b (PEG-Intron) for Neurofibromatosis Type 1 Related Unresectable, Symptomatic or Life-Threatening Plexiform NeurofibromasCompleted Study; data analyses ongoing0-21 YearsNCI Growth
08-C-0020A Phase II Study of ZD6474 (Vandetanib) in Patients with Von Hippel Lindau Disease and Renal TumorsCompleted Study; data analyses ongoing18-125 YearsNCI Growth
07-I-0183The Collection of Research Samples and/or Data for Repository from Related or Unrelated Hematopoietic Stem Cell Transplantation Recipients for the National Marrow Donor Program Participants currently recruited/enrolled2-125 YearsNIAIDFactor
07-H-0113Procurement and Analysis of Blood, Bone Marrow, and Buccal Mucosa Samples from Healthy Volunteers to Support Clinical and Translational Research Projects in the NHLBIParticipants currently recruited/enrolled8-125 YearsNHLBIFactor
07-C-0121Phase 2 Study of the C-Met RTK Inhibitor Foretinib (Formerly GSK 1363089) in Subjects with Papillary Renal Cell Carcinoma (PRC)Completed Study; data analyses ongoing18-125 YearsNCI Growth
06-M-0214PET Measurement of Regional Rates of Cerebral Protein Synthesis in Subjects with Fragile X SyndromeCompleted Study; data analyses ongoing18-24 YearsNIMH Growth
06-I-0015Screening Protocol for Genetic Diseases of Lymphocyte Homeostasis and Programmed Cell DeathParticipants currently recruited/enrolled0-125 YearsNIAIDGrowth
06-EI-0236National Ophthalmic Genotyping and Phenotyping Network Stage 1 - Creation of DNA Repository for Inherited Ophthalmic DiseasesNo longer recruiting/follow-up only2-125 YearsNEI Factor
06-C-0134Natural History and Biology of Dermal Neurofibromas in Neurofibromatosis Type 1Completed Study; data analyses ongoing20-99 YearsNCI Growth
05-I-0213Screening and Baseline Assessment of Patients with Abnormalities of Immune FunctionParticipants currently recruited/enrolled0-125 YearsNIAIDFactor
05-CH-0013Adrenal Function in Critical IllnessCompleted Study; data analyses ongoing15-80 YearsNICHDFactor
05-C-0152Variation in Gene Expression in Neurofibromatosis Type 1Completed Study; data analyses ongoing2-100 YearsNCI Growth
04-N-0056The Neural Immune Mechanisms and Genetic Influences on Chronic Pelvic Pain in Women with EndometriosisCompleted Study; data analyses ongoing18-50 YearsNINDSGrowth
04-HG-0127Clinical and Basic Investigations of Methylmalonic Acidemia (MMA) and Related DisordersParticipants currently recruited/enrolled0-125 YearsNHGRIGrowth
04-E-0053Personalized Environment and Genes StudyParticipants currently recruited/enrolled18-130 YearsNIEHSFactor
04-CH-0077Investigations of Bone-Related Connective Tissue DisordersCompleted Study; data analyses ongoing0-70 YearsNICHDGrowth
04-C-0281Natural History Study of Clinical and Biological Factors Determining Outcomes in Chronic Graft-Versus-Host DiseaseParticipants currently recruited/enrolled1-125 YearsNCI Factor
04-C-0238A Phase 2 Study of 17-Allylamino-17-Demethoxygeldanamycin in Patients with Von Hippel Lindau Disease and Renal TumorsCompleted Study; data analyses ongoing18-125 YearsNCI Growth
03-M-0211Family Study of Affective and Anxiety Spectrum DisordersParticipants currently recruited/enrolled7-120 YearsNIMH Factor
03-H-0105The Determination of Genetic Basis Of ImmunodeficiencyParticipants currently recruited/enrolled0-125 YearsNHLBIFactor
03-E-0099Pathogenic Studies In Families With Twins Or Siblings Discordant For Systemic Rheumatic DisordersCompleted Study; data analyses ongoing2-125 YearsNIEHSFactor
02-I-0202Leukapheresis Procedures to Obtain Plasma and Lymphocytes for Research Studies on Antiretroviral-Naive HIV-Infected PatientsParticipants currently recruited/enrolled18-120 YearsNIAIDFactor
02-I-0086Evaluation of Viral Factors and Immune Parameters to Study HIV-Specific ImmunityParticipants currently recruited/enrolled18-125 YearsNIAIDFactor
02-C-0268Prospective Study of Prophylactic Salpingo-Oophorectomy and Longitudinal CA-125 Screening Among Women at Increased Genetic Risk of Ovarian CancerCompleted Study; data analyses ongoing19-100 YearsNCI Factor
02-C-0212Clinical, Genetic, Behavioral, Laboratory and Epidemiologic Characterization of Individuals and Families at High Risk of Breast/Ovarian CancerCompleted Study; data analyses ongoing18-100 YearsNCI Factor
02-C-0211Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of MelanomaParticipants currently recruited/enrolled2-125 YearsNCI Factor
02-C-0210Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of Blood and Lymph Node MalignancyParticipants currently recruited/enrolled0-125 YearsNCI Factor
02-C-0178Multidisciplinary Etiologic Study of Familial Testicular CancerNo longer recruiting/follow-up only12-125 YearsNCI Factor
02-C-0052Etiologic Investigation of Cancer Susceptibility in Inherited Bone Marrow Failure Syndromes: A Natural History StudyParticipants currently recruited/enrolled0-125 YearsNCI Factor
01-M-0192Fluoxetine's Effects on Attention and Emotional Memory in Anxious and Depressed Youth and AdultsParticipants currently recruited/enrolled8-65 YearsNIMH Factor
01-M-0185Effects of Arousal and Stress on Classical ConditioningCompleted Study; data analyses ongoing18-50 YearsNIMH Factor
01-HG-0109Natural History Study of the Clinical and Molecular Manifestations of Smith-Magenis Syndrome (SMS)No longer recruiting/follow-up only0-125 YearsNHGRIGrowth
01-DC-0228Clinical and Molecular Analysis of Enlarged Vestibular AqueductsCompleted Study; data analyses ongoing0-99 YearsNIDCDFactor
01-C-0009Breast Imaging Screening Studies in Women at High Genetic Risk of Breast Cancer: Annual Follow-up StudyCompleted Study; data analyses ongoing18-100 YearsNCI Factor
00-N-0089Genetic Analysis of the Chiari I MalformationCompleted Study; data analyses ongoing1-125 YearsNINDSFactor
00-M-0085Structural and Functional Imaging of Neuropsychiatric Patients and Normal Volunteers with 3.0 Tesla MRI and Magnetoencephalography (MEG)Participants currently recruited/enrolled18-125 YearsNIMH Factor
00-I-0159Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection Syndrome (HIES)Participants currently recruited/enrolled0-125 YearsNIAIDFactor
00-H-0051Cutaneous Tumorigenesis in Patients with Tuberous SclerosisParticipants currently recruited/enrolled18-90 YearsNHLBIGrowth
00-CH-0136A Trial of Pamidronate in Children with Osteogenesis ImperfectaCompleted Study; data analyses ongoing2-17 YearsNICHDGrowth
00-C-0078Collection of Blood, Fluid, Bone Marrow, Tumor, or Tissue Samples from Patients with Cancer or Normal VolunteersParticipants currently recruited/enrolled18-125 YearsNCI Factor
99-DK-0002Diabetes and Heart Disease Risk in BlacksParticipants currently recruited/enrolled18-70 YearsNIDDKFactor
98-D-0145Screening and Natural History of Patients with Polyostotic Fibrous Dysplasia and the McCune-Albright SyndromeParticipants currently recruited/enrolled0-100 YearsNIDCRGrowth
98-CH-0081Clinical and Basic Investigations into Smith-Lemli-Opitz SyndromeCompleted Study; data analyses ongoing0-125 YearsNICHDGrowth
97-CH-0064Evaluation and Intervention for Ambulation, Growth, and Basilar Invagination in Osteogenesis ImperfectaCompleted Study; data analyses ongoing0-10 YearsNICHDGrowth
96-H-0100Role of Genetic Factors in the Pathogenesis of Lung DiseaseParticipants currently recruited/enrolled2-90 YearsNHLBIFactor
96-CH-0033An Open, Randomized, Long-Term Clinical Trial of Flutamide, Testolactone, and Reduced Hydrocortisone Dose vs. Conventional Treatment of Children with Congenital Adrenal HyperplasiaNo longer recruiting/follow-up only2-18 YearsNICHDGrowth
95-CH-0059Definition of the Genotype and Clinical Phenotype of Primary Pigmented Nodular Adrenocortical Disease (PPNAD), Carney Complex, Peutz-Jeghers Syndrome and Related ConditionsCompleted Study; data analyses ongoing3-70 YearsNICHDGrowth
94-HG-0132The Phenotype and Etiology of Proteus SyndromeParticipants currently recruited/enrolled0-125 YearsNHGRIGrowth
94-E-0165Studies in the Natural History and Pathogenesis of Childhood-Onset and Adult-Onset Idiopathic Inflammatory MyopathiesParticipants currently recruited/enrolled2-100 YearsNIEHSFactor
94-DK-0133Genetic Markers for Focal Segmental GlomerulosclerosisCompleted Study; data analyses ongoing1-125 YearsNIDDKFactor
94-C-0074Treatment and Natural History Study of Lymphomatoid GranulomatosisParticipants currently recruited/enrolled12-125 YearsNCI Factor
94-AR-0066Studies of the Pathogenesis and Natural History of Systemic Lupus Erythematosus (SLE)Participants currently recruited/enrolled9-125 YearsNIAMSFactor
93-C-0133Dose-Adjusted EPOCH Chemotherapy and Rituximab (CD20+) in Adults and Children with Previously Untreated Patients with Aggressive Non-Hodgkin's LymphomaNo longer recruiting/follow-up only12-125 YearsNCI Factor
92-I-0125A Study of Viral Burden in Peripheral Blood Versus Lymphoid and Bone Marrow Tissue in HIV-Infected IndividualsParticipants currently recruited/enrolled18-125 YearsNIAIDFactor
92-CH-0034Studies of Growth Deficiency and Growth Hormone Treatment in Children with Osteogenesis Imperfecta Types III and IVCompleted Study; data analyses ongoing3-16 YearsNICHDGrowth
91-I-0140Studies of the Pathogenesis of HIV Infection in Human Peripheral Blood Cells and/or Body Fluids in HIV-Infected and HIV-Uninfected VolunteersParticipants currently recruited/enrolled18-125 YearsNIAIDFactor
89-N-0045Evaluation of Progression in Multiple Sclerosis by Magnetic Resonance Imaging (MRI)Participants currently recruited/enrolled18-125 YearsNINDSFactor
89-I-0158Studies of Immune Regulation in Patients with Common Variable Immunodeficiency and Related Humoral Immunodeficiency SyndromesParticipants currently recruited/enrolled2-125 YearsNIAIDFactor
88-CH-0032Specificity of Mother-Infant Interaction: The Influence of Maternal Age, Employment Status, and Parenthood StatusCompleted Study; data analyses ongoing0-23 YearsNICHDGrowth
86-HG-0096Studies of Genetic Heterogeneity in Patients with Lysosomal Storage DisordersEnrolling by Invitation0-125 YearsNHGRIFactor
81-M-0126The Evaluation of Women with Menstrually Regulated Mood and Behavioral DisordersParticipants currently recruited/enrolled18-50 YearsNIMH Factor
79-H-0100Teaching Protocol for the Evaluation of Plasma LipoproteinsNo longer recruiting/follow-up only2-99 YearsNHLBIFactor
78-HG-0093Use of Cysteamine in the Treatment of CystinosisParticipants currently recruited/enrolled0-125 YearsNHGRIGrowth
78-C-0039Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of CancerNo longer recruiting/follow-up only0-125 YearsNCI Factor
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