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74 Studies found from all possible combinations of your search terms. Select a protocol that you wish to review.
Protocol Number Title Protocol Status Min-Max Age Institute Keywords
000809-IA Pilot Study of Fecal Microbiota Transplantation for Chronic Granulomatous Disease-Associated ColitisParticipants currently recruited/enrolled10-60 YearsNIAIDImmunodeficiency
000612-CPhase 1 Study of NT-I7 (rhIL-7-hyFc) for the Treatment of Kaposi Sarcoma in Patients With or Without Infection with HIVParticipants currently recruited/enrolled18-125 YearsNCI Immunodeficiency
000478-CA Phase I/II Trial of Allogeneic Reduced-Intensity, HLA-Haploidentical Bone Marrow Transplantation Followed by GVHD Prophylaxis with Cyclophosphamide, Bortezomib and Maraviroc for Hematologic Malignancies in People Living with HIV (PLWH)Participants currently recruited/enrolled12-125 YearsNCI Immunodeficiency
000404-CA Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Subjects with VEXAS (Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic) SyndromeParticipants currently recruited/enrolled18-75 YearsNCI Immunodeficiency
000392-IMetabolic Profiling of Immune Responses in Immune-Mediated DiseasesParticipants currently recruited/enrolled18-75 YearsNIAIDImmunodeficiency
000277-CImaging and Biopsy of HIV-Infected Individuals Undergoing Analytic Treatment InterruptionParticipants currently recruited/enrolled18-125 YearsNCI Immunodeficiency
000272-HDefining the Genetic Etiology of Suppurative Lung Disease in Children and AdultsParticipants currently recruited/enrolled5-45 YearsNHLBIImmunodeficiency
21-I-0003A Phase 1/2 Study to Evaluate the Safety, Tolerability and Efficacy, of JSP191 for Hematopoietic Cell Transplantation Conditioning to Achieve Engraftment and Immune Reconstitution in Subjects with SCIDParticipants currently recruited/enrolled3-125 YearsNIAIDImmunodeficiency
21-C-0026A Phase I/II Study of Abemaciclib in Patients with HIV-associated and HIV-negative Kaposi SarcomaParticipants currently recruited/enrolled18-125 YearsNCI Immunodeficiency
20-I-0084Sample Collection for Systems Evaluation of Patients with Unknown or Incompletely Characterized Immune DefectsParticipants currently recruited/enrolled2-125 YearsNIAIDImmunodeficiency
20-C-0167Close Assessment and Testing for Chronic Graft-vs-Host Disease (CATCH Study)Participants currently recruited/enrolled18-125 YearsNCI Immunodeficiency
20-C-0070A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Patients with Inborn Errors of ImmunityParticipants currently recruited/enrolled4-69 YearsNCI Immunodeficiency
20-C-0011Phase 1 Study of Recombinant Human IL-15 (rhIL-15) and Mogamulizumab for Patients with Refractory or Relapsed Adult T-Cell Leukemia and Mycosis Fungoides/Sezary SyndromeCompleted Study; data analyses ongoing18-125 YearsNCI Immunodeficiency
19-I-0069Phase I Open-Label Study of Safety and Immunogenicity of AD4-HIV Envelope Vaccine Vectors in Healthy VolunteersParticipants currently recruited/enrolled18-65 YearsNIAIDImmunodeficiency
19-CC-0063Impact of Steady State Cobicistat and Darunavir/Cobicistat on the Pharmacokinetics and Pharmacodynamics of Oral Anticoagulants (Rivaroxaban, Apixaban) in Healthy VolunteersParticipants currently recruited/enrolled18-65 YearsCC Immunodeficiency
19-C-0016Natural History and Biospecimen Acquisition Study for Children and Adults with Rare Solid TumorsParticipants currently recruited/enrolled0-125 YearsNCI 47
18-I-0128Send-In Sample Collection to Achieve Genetic and Immunologic Characterization of Primary ImmunodeficienciesParticipants currently recruited/enrolled0-99 YearsNIAIDImmunodeficiency
18-I-0041Investigating the Mechanistic Biology of Primary Immunodeficiency DisordersParticipants currently recruited/enrolled0-75 YearsNIAIDImmunodeficiency
18-I-0030VRC 603: A Phase 1 Dose-Escalation Study of the Safety of AAV8-VRC07 (VRC-HIVAAV070-00-GT) Recombinant AAV Vector Expressing VRC07 HIV-1 Neutralizing Antibody in Antiretroviral-Treated, HIV-1 Infected Adults with Controlled ViremiaNo longer recruiting/follow-up only18-65 YearsNIAIDImmunodeficiency
18-CC-0117PET Imaging of the Dopaminergic and Serotonergic Systems in Treated HIV Positive SubjectsCompleted Study; data analyses ongoing18-70 YearsCC Immunodeficiency
18-CC-0087Impact of Weekly Administration of Rifapentine and Isoniazid on Steady State Pharmacokinetics of Tenofovir Alafenamide in Healthy VolunteersCompleted Study; data analyses ongoing18-65 YearsCC Immunodeficiency
18-CC-0013A Randomized, Double-Blind, Placebo-Controlled Study of a Single Dose of Pembrolizumab in HIV-Infected PatientsParticipants currently recruited/enrolled18-99 YearsCC Immunodeficiency
18-C-0135Phase II Trial of Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or DysregulationParticipants currently recruited/enrolled4-125 YearsNCI Immunodeficiency
17-I-0163Natural History of Intestinal Inflammation in Patients with Primary Immune DysregulationsParticipants currently recruited/enrolled3-125 YearsNIAIDImmunodeficiency
17-I-0122NIAID Centralized Sequencing ProtocolParticipants currently recruited/enrolled0-125 YearsNIAIDImmunodeficiency
17-C-0174Molecular Characterization of Viral-associated Tumors, Tumors Occurring in the Setting of HIV or Other Immune Disorders and Castleman DiseaseParticipants currently recruited/enrolled18-125 YearsNCI Immunodeficiency
17-C-0048Anti-CD30 CAR T Cells with Fully-human Binding Domains for Treating CD30-expressing Lymphomas Including Anaplastic Large Cell LymphomasCompleted Study; data analyses ongoing18-73 YearsNCI Immunodeficiency
16-I-0165An open-label, non-randomized extension study to evaluate the long term safety, tolerability, efficacy and pharmacokinetics of CDZ173 (leniolisib) in patients with APDS/PASLI (Activated phosphoinositide 3-kinase delta syndrome/p110 delta-activating mutatNo longer recruiting/follow-up only12-75 YearsNIAIDImmunodeficiency
16-CC-0112Impact of Once-Weekly Rifapentine and Isoniazid on the Steady State Pharmacokinetics of Dolutegravir and Darunavir Boosted with Cobicistat in Healthy VolunteersCompleted Study; data analyses ongoing18-65 YearsCC Immunodeficiency
16-C-0066Phase I Study of MK-3475 (Pembrolizumab) in Patients with Human Immunodeficiency Virus (HIV) and Relapsed/Refractory or Disseminated Malignant NeoplasmParticipants currently recruited/enrolled18-125 YearsNCI Immunodeficiency
16-C-0003Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary ImmunodeficienciesParticipants currently recruited/enrolled4-75 YearsNCI Immunodeficiency
15-I-0135An open-label, non-randomized, within-patient dose-finding study followed by a randomized, subject, investigator and sponsor-blinded placebo controlled study to assess the efficacy and safety of CDZ173 (leniolisib) in patients with APDS/PASLI (Activated Completed Study; data analyses ongoing12-75 YearsNIAIDImmunodeficiency
15-DK-0079Observational Study of Hepatitis B Virus (HBV) in Patients Coinfected with Human Immunodeficiency Virus (HIV)Completed Study; data analyses ongoing18-125 YearsNIDDKImmunodeficiency
14-I-0185A Phase III Double-Blind Randomized Crossover Study of Plerixafor Versus G-CSF in the Treatment of Patients with WHIM Syndrome.Completed Study; data analyses ongoing10-75 YearsNIAIDImmunodeficiency
14-I-0146The Pathogenesis and Genetics of Disseminated or Refractory CoccidioidomycosisParticipants currently recruited/enrolled2-100 YearsNIAIDImmunodeficiency
14-I-0089A Retrospective and Cross-Sectional Analysis of Patients Treated for Severe Combined Immunodeficiency (SCID) Since January 1, 1968Enrolling by Invitation2-125 YearsNIAIDImmunodeficiency
14-I-0072A Prospective Natural History Study of Diagnosis, Treatment and Outcomes of Children with SCID DisordersCompleted Study; data analyses ongoing2-125 YearsNIAIDImmunodeficiency
14-I-0039Elite Controller and ART-Treated HIV+ Statin Versus ASA Treatment Intervention StudyCompleted Study; data analyses ongoing18-125 YearsNIAIDImmunodeficiency
14-I-0020Hematopoietic Stem Cell Mobilization in Idiopathic CD4 Lymphocytopenia Patients and Healthy Controls for the Study of T Cell Maturation and Trafficking in Murine ModelsParticipants currently recruited/enrolled18-65 YearsNIAIDImmunodeficiency
14-I-0009Characterization and Management of Patients with HIV-1 Infection Who Experience Virologic Failure Despite Combination Antiretroviral TherapyCompleted Study; data analyses ongoing18-100 YearsNIAIDImmunodeficiency
13-N-0149An Evaluation of HIV-associated Neurocognitive Disorders (HAND) in Virologically Controlled PatientsParticipants currently recruited/enrolled18-125 YearsNINDSImmunodeficiency
13-N-0135Pilot Study of Raltegravir, an Integrase Inhibitor, in Human T-Cell Lymphotrophic Virus-1(HTLV-1) Associated Myelopathy, Tropical Spastic Paraparesis (HAM/TSP)Completed Study; data analyses ongoing18-125 YearsNINDSImmunodeficiency
13-N-0017Natural History Study of Progressive Multifocal Leukoencephalopathy (PML)Participants currently recruited/enrolled2-125 YearsNINDSImmunodeficiency
13-I-0062A Double Blind Randomized Placebo Controlled Study Examining the Effects of a Non-Absorbable (Rifaximin) Antibiotic on the Chronic Immune Activation Observed In HIV-infected SubjectsCompleted Study; data analyses ongoing18-65 YearsNIAIDImmunodeficiency
13-HG-0199NIH Participation to USIDNET RegistryParticipants currently recruited/enrolled0-125 YearsNHGRIImmunodeficiency
13-C-0132Allogeneic Hematopoietic Stem Cell Transplant for Patients with Mutations in GATA2 or the MonoMAC SyndromeParticipants currently recruited/enrolled8-70 YearsNCI Immunodeficiency
12-C-0047A Phase I/II Study of the Safety, Pharmacokinetics and Efficacy of Pomalidomide (CC-4047) in the Treatment of Kaposi Sarcoma in Individuals With or Without HIVCompleted Study; data analyses ongoing18-125 YearsNCI Immunodeficiency
11-I-0057Effect of Interferon Alpha 2b Intensification on HIV-1 Residual Viremia in Individuals Suppressed on Antiretroviral TherapyCompleted Study; data analyses ongoing18-65 YearsNIAIDImmunodeficiency
11-I-0007Lentiviral Gene Transfer for Treatment of Children Older Than 2 Years of Age with X-Linked Severe Combined ImmunodeficiencyClinical hold/Recruitment or enrollment suspended2-40 YearsNIAIDImmunodeficiency
11-CC-0152The Natural History of Liver Disease in a Cohort of Participants with Hepatitis B and/or Hepatitis C with or without HIV InfectionCompleted Study; data analyses ongoing18-99 YearsCC Immunodeficiency
10-I-0014The Natural History of Severe Viral Infections and Characterization of Immune DefectsParticipants currently recruited/enrolled2-125 YearsNIAIDImmunodeficiency
10-CC-0053Collection of Bone Marrow from Healthy Volunteers and Patients for the Production of Clinical Bone Marrow Stromal Cell (BMSC) ProductsCompleted Study; data analyses ongoing18-125 YearsCC Immunodeficiency
10-C-0201Apheresis and CD34+ Selection of Mobilized Peripheral Blood CD34+ Cells from Patients with DOCK8 Deficiency, LAD-1, and GATA2 DeficiencyParticipants currently recruited/enrolled18-40 YearsNCI Immunodeficiency
10-C-0174Related and Unrelated Donor Hematopoietic Stem Cell Transplant for DOCK8 DeficiencyParticipants currently recruited/enrolled4-125 YearsNCI Immunodeficiency
09-I-0200A Phase I Study of MozobilTM in the Treatment of Patients with WHIMSParticipants currently recruited/enrolled18-75 YearsNIAIDImmunodeficiency
09-I-0133Establishing Fibroblast-derived Cell Lines from Skin/Tissue Biopsies of Patients with Immunodeficiency or Immunodysregulation DisordersEnrolling by Invitation2-85 YearsNIAIDImmunodeficiency
09-I-0126Pathogenesis and Genetic Basis of Physical Induced Urticarial SyndromesParticipants currently recruited/enrolled2-90 YearsNIAIDImmunodeficiency
09-I-0102Etiology, Pathogenesis, and Natural History of Idiopathic CD4+ LymphocytopeniaParticipants currently recruited/enrolled18-125 YearsNIAIDImmunodeficiency
09-I-0086Screening Protocol for Genetic Diseases of Allergic InflammationParticipants currently recruited/enrolled0-99 YearsNIAIDImmunodeficiency
09-H-0172Natural History of BronchiectasisParticipants currently recruited/enrolled5-125 YearsNHLBIImmunodeficiency
09-C-0024A Phase I Study of Quadrivalent Human Papilloma Virus (HPV) (Types 6, 11, 16, 18) Recombinant Vaccine in HIV-Infected and HIV-Negative Pre-Adolescents, Adolescents and Young AdultsCompleted Study; data analyses ongoing12-26 YearsNCI Immunodeficiency
08-HG-0059Studies of Skin Microflora in Healthy Individuals and Atopic Dermatitis PatientsParticipants currently recruited/enrolled2-125 YearsNHGRIImmunodeficiency
06-I-0015Screening Protocol for Genetic Diseases of Lymphocyte Homeostasis and Programmed Cell DeathParticipants currently recruited/enrolled0-125 YearsNIAIDImmunodeficiency
05-I-0213Screening and Baseline Assessment of Patients with Abnormalities of Immune FunctionParticipants currently recruited/enrolled0-125 YearsNIAIDImmunodeficiency
04-C-0281Natural History Study of Clinical and Biological Factors Determining Outcomes in Chronic Graft-Versus-Host DiseaseParticipants currently recruited/enrolled1-125 YearsNCI Immunodeficiency
03-H-0105The Determination of Genetic Basis Of ImmunodeficiencyParticipants currently recruited/enrolled0-125 YearsNHLBIImmunodeficiency
01-C-0129Eligibility Screening for the NIH Intramural Research Program Clinical ProtocolsEnrolling by Invitation0-125 YearsNCI Immunodeficiency
01-C-0030Short-Course EPOCH - Rituximab in Untreated CD-20+ HIV-Associated LymphomasNo longer recruiting/follow-up only18-125 YearsNCI Immunodeficiency
00-I-0159Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection Syndrome (HIES)Participants currently recruited/enrolled0-125 YearsNIAIDImmunodeficiency
00-HG-0209Molecular and Clinical Studies of Primary Immunodeficiency DiseasesNo longer recruiting/follow-up only3-125 YearsNHGRIImmunodeficiency
95-I-0066Genetic Analysis of Immune DisordersParticipants currently recruited/enrolled0-125 YearsNIAIDImmunodeficiency
94-DK-0133Genetic Markers for Focal Segmental GlomerulosclerosisCompleted Study; data analyses ongoing1-125 YearsNIDDKImmunodeficiency
92-I-0125A Study of Viral Burden in Peripheral Blood Versus Lymphoid and Bone Marrow Tissue in HIV-Infected IndividualsParticipants currently recruited/enrolled18-125 YearsNIAIDImmunodeficiency
89-I-0158Studies of Immune Regulation in Patients with Common Variable Immunodeficiency and Related Humoral Immunodeficiency SyndromesParticipants currently recruited/enrolled2-125 YearsNIAIDImmunodeficiency
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