NIH Clinical Center: Search the Studies

Search the Studies

16 Studies found from all possible combinations of your search terms. Select a protocol that you wish to review.

Protocol Number	Title	Protocol Status	Min-Max Age	Institute	Keywords
000860-C	A Phase I/II Study of Zotiraciclib for Recurrent High-Grade Gliomas with Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations	Recruitment has not started	18-125 Years	NCI	Glioma
22-C-0003	Feasibility of Evaluating Abemaciclib Neuropharmacokinetics of Diffuse Midline Glioma Using Intratumoral Microdialysis	Participants currently recruited/enrolled	18-39 Years	NCI	Glioma
21-C-0015	Phase II Trial Evaluating the Association of Peripheral Blood Immunologic Response to Therapeutic Response to Adjuvant Treatment with Immune Checkpoint Inhibition (ICI) in Patients with Newly Diagnosed Glioblastoma or Gliosarcoma	Participants currently recruited/enrolled	18-125 Years	NCI	Glioma
20-C-0069	A First-In-Human Phase I Single-Agent Dose-Escalation, Food Effect and Dose Expansion Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms	Participants currently recruited/enrolled	18-125 Years	NCI	Glioma
19-C-0096	Studying the Biology of IDH-mutant Gliomas via Longitudinal Observation of 2-Hydroxyglutarate (2-HG) Using MR Spectroscopy	Participants currently recruited/enrolled	18-125 Years	NCI	Glioma
19-C-0006	Phase II Trial Evaluating Nivolumab In Patients With IDH-Mutant Gliomas With And Without Hypermutator Phenotype	Participants currently recruited/enrolled	18-125 Years	NCI	Glioma
18-N-0077	Cytokine Microdialysis For Real Time Immune Monitoring in Glioblastoma Patients Undergoing Checkpoint Blockade	Completed Study; data analyses ongoing	18-125 Years	NINDS	Glioma
18-C-0080	Feasibility and Preliminary Efficacy of an Enhanced Mindfulness Intervention for Children and Young Adults with High Grade or High-Risk Cancer and Their Caregivers: A Pilot Randomized Controlled Trial	Completed Study; data analyses ongoing	5-125 Years	NCI	Glioma
17-C-0175	CC-4047-BRN-001: A Phase 2 Clinical Study of Pomalidomide (CC-4047) Monotherapy for Children and Young Adults with Recurrent or Progressive Primary Brain Tumors	Completed Study; data analyses ongoing	3-20 Years	NCI	Glioma
17-C-0037	Phase II Trial of LB100, a Protein Phosphatase 2A Inhibitor, in Recurrent Glioblastoma	Participants currently recruited/enrolled	18-125 Years	NCI	Glioma
17-C-0034	A Randomized, Double Blind Phase II Trial of Surgery, Radiation Therapy Plus Temozolomide and Pembrolizumab with and without HSPPC-96 in Newly Diagnosed Glioblastoma (GBM)	Completed Study; data analyses ongoing	18-125 Years	NCI	Glioma
16-C-0151	Evaluation of the Natural History of and Specimen Banking for Patients with Tumors of the Central Nervous System	Participants currently recruited/enrolled	18-125 Years	NCI	Glioma
16-C-0097	Phase 1 Trial of Panobinostat in Children with Diffuse Intrinsic Pontine Glioma	Completed Study; data analyses ongoing	2-21 Years	NCI	Glioma
16-C-0011	A Phase I-II Trial of Everolimus and Sorafenib in Patients with Recurrent High-Grade Gliomas	Completed Study; data analyses ongoing	18-125 Years	NCI	Glioma
08-C-0079	Natural History Study and Longitudinal Assessment of Children, Adolescents, and Adults with Neurofibromatosis Type 1	No longer recruiting/follow-up only	0-125 Years	NCI	Glioma
06-C-0219	An Exploratory Study of Biologic and Pathophysiologic Effects of Radiation Therapy in Pediatric Patients with Central Nervous System Tumors	Completed Study; data analyses ongoing	0-21 Years	NCI	Glioma