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87 Studies found from all possible combinations of your search terms. Select a protocol that you wish to review.
Protocol Number
Title
Protocol Status
Min-Max Age
Institute
Keywords
001109-C
Defining the Natural History of Squamous Cell Carcinoma in Fanconi Anemia
Participants currently recruited/enrolled
8-125 Years
NCI
Early
001092-C
Exploring the Role of Palliative Care in Phase 1 Enrolled Pediatric Oncology Patients
Enrolling by Invitation
18-125 Years
NCI
Early
001058-DK
A Phase 1b/2a Open-label Multiple-ascending Dose Exploratory Study of CRN04894 in ACTH-dependent Cushing's Syndrome (Cushing's Disease or Ectopic ACTH Syndrome)
Recruitment has not started
18-75 Years
NIDDK
Early
001056-C
Longitudinal Early Advance Care Planning Discussions and Documentation (LEADD) Program: An Exploratory Study in Adolescents and Young Adults (AYAs) Receiving Hematopoietic Stem Cell Transplant
Participants currently recruited/enrolled
18-125 Years
NCI
Early
000957-HG
A Phase 1/2, Open-Label, Single Dose Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of SEL-302 (MMA-101 following administration of SEL-110) in Pediatric Subjects with Mut Subtype Isolated Methylmalonic Acidemia (MMA)
Participants currently recruited/enrolled
3-17 Years
NHGRI
Early
000912-HG
Genetic and Social Network Correlates of Rheumatoid Arthritis Outcomes in Hispanic Populations: A Prospective Study
Participants currently recruited/enrolled
18-125 Years
NHGRI
Early
000906-I
A Phase 2 Randomized, Double-Blinded Cross-Over Design Study of the Early Metabolic Effects of Dolutegravir or Tenofovir Alefenamide in Healthy Volunteers
Recruitment has not started
18-55 Years
NIAID
Early
000715-CH
Biorepository in Participants Who Undergo OTC for Gonadotoxic Therapy
Participants currently recruited/enrolled
4-35 Years
NICHD
Early
000686-CH
Intrathecal 2-Hydroxypropyl-Beta-Cyclodextrin for Neurological Decline in Patients with Niemann-Pick Disease Type C1
Participants currently recruited/enrolled
18-125 Years
NICHD
Early
000628-C
A Study of Prospective Monitoring of Subjects with Biochemically Recurrent Prostate Cancer Using 18F-DCFPyL
Participants currently recruited/enrolled
18-125 Years
NCI
Early
000613-C
Phase I/II Trial to Determine the Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination with Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis after Reduced Intensity Conditioning and Peripheral Blood St
Participants currently recruited/enrolled
12-125 Years
NCI
Early
000611-C
A Phase II Trial of Focal Ultrahypofractionated Stereotactic Radiation Therapy for the Treatment of Unifocal Prostate Cancer
Recruitment has not started
18-125 Years
NCI
Early
000596-C
Phase II Study of Olaparib in Subjects with Advanced Pancreatic Acinar Cell Carcinoma
Participants currently recruited/enrolled
18-125 Years
NCI
Early
000489-C
Phase I/II Study Using Prophylactic Donor Lymphocyte Infusion Early Post-Transplant After Allogeneic Hematopoietic Cell Transplantation Using Post-Transplantation Cyclophosphamide for High-Risk Hematologic Malignancies
Clinical hold/Recruitment or enrollment suspended
12-125 Years
NCI
Early
000481-C
Phase II Trial of 18F-DCFPyL Imaging as a Method to Assess Treatment Response to Stereotactic Body Radiation Therapy
Participants currently recruited/enrolled
18-125 Years
NCI
Early
000479-H
Observational Study to Deeply Phenotype Major Organs in Sickle Cell Disease After Curative Therapies
Participants currently recruited/enrolled
18-125 Years
NHLBI
Early
000473-C
A Randomized Phase II Study of Systemic Chemotherapy with or without HAI FUDR-Dexamethasone in Patients with Unresectable Intrahepatic Cholangiocarcinoma
Participants currently recruited/enrolled
18-125 Years
NCI
Early
000264-C
A Pharmacodynamics-Driven Trial of Talazoparib, an Oral PARP Inhibitor, in Patients With Advanced Solid Tumors and Aberrations in Genes Involved in DNA Damage Response
Participants currently recruited/enrolled
18-125 Years
NCI
Early
000212-I
Induced Blood-Stage Plasmodium Vivax Infection with HMPBS02-Pv Challenge Agent in Healthy Malaria-Naive Adults to Produce a Plasmodium Vivax Parasite Cell Bank for Future Studies
No longer recruiting/follow-up only
18-50 Years
NIAID
Early
000194-C
A Phase I Trial of ProAgio, an anti- alpha-v-beta3 Integrin Cytotoxin, for Previously Treated Advanced Pancreatic Cancer and Other Solid Tumor Malignancies
Participants currently recruited/enrolled
18-125 Years
NCI
Early
000106-CH
Gonadal Tissue Freezing for Fertility Preservation in Individuals at risk for Ovarian Dysfunction and Premature Ovarian Insufficiency
Participants currently recruited/enrolled
4-21 Years
NICHD
Early
21-C-0017
Magnetic Resonance Image (MRI) Guided High Energy Ultrasound for Focal Prostate Cancer Ablation
Recruitment has not started
18-125 Years
NCI
Early
20-N-0105
Layer-specific Contribution to Consolidation of Skill Learning in the Primary Motor Cortex
Participants currently recruited/enrolled
18-50 Years
NINDS
Early
20-N-0019
The Effect of Vorinostat on ACTH Producing Pituitary Adenomas in Cushing's Disease
Participants currently recruited/enrolled
18-125 Years
NINDS
Early
20-I-0140
A Double-Blind, Randomized, Placebo-Controlled, Phase 1, Single-Dose, Dose-Escalating Trial of Long-Acting Recombinant Human IL-7 (NT-I7) for COVID-19
Participants currently recruited/enrolled
19-75 Years
NIAID
Early
20-H-0080
Red Cell Half Life Determination in Patients with and without Sickle Cell Disease
No longer recruiting/follow-up only
18-100 Years
NHLBI
Early
20-H-0033
Early Initiation of Oral Therapy with Cyclosporine and Eltrombopag for Treatment Naive Severe Aplastic Anemia (SAA)
Participants currently recruited/enrolled
3-125 Years
NHLBI
Early
20-E-0108
A Prospective Natural History Study of Smoking, Immune Cell Profiles, Epigenetics and COVID-19
Completed Study; data analyses ongoing
30-55 Years
NIEHS
Early
20-C-0150
Phase II Randomized Trial of Bethesda Protocol Compared to Cambridge Method for Detection of Early Stage Gastric Cancer in CDH1 Mutation Carriers
Recruitment has not started
18-125 Years
NCI
Early
20-C-0107
Clinical, Genetic, and Epidemiologic Study of Children and Adults with RASopathies
Participants currently recruited/enrolled
0-125 Years
NCI
Early
20-C-0106
Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients with BAP1 Tumor Predisposition Syndrome
Participants currently recruited/enrolled
30-125 Years
NCI
Early
20-C-0103
Investigation of the B- and T-cell Repertoire and Immune Response in Patients with Acute and Resolved COVID-19 Infection
Participants currently recruited/enrolled
18-125 Years
NCI
Early
19-H-0111
Early Clonal Dynamics During Venetoclax Treatment for Chronic Lymphocytic Leukemia (CLL)
Participants currently recruited/enrolled
18-125 Years
NHLBI
Early
19-H-0100
Best Noninvasive Predictor of Renal Function in Assessing Adult Sickle Nephropathy
Completed Study; data analyses ongoing
18-125 Years
NHLBI
Early
19-H-0088
NHLBI DIR Transcatheter Mitral Cerclage Annuloplasty Early Feasibility Study
No longer recruiting/follow-up only
21-99 Years
NHLBI
Early
19-E-0110
Reproductive Axis Maturation in the Early Post-Menarchal Years: A Pilot Study
Participants currently recruited/enrolled
8-34 Years
NIEHS
Early
19-DK-0050
The Use of 124-I-PET/CT Whole Body and Lesional Dosimetry in Differentiated Thyroid Cancer
Participants currently recruited/enrolled
18-125 Years
NIDDK
Early
18-N-0083
ASPIRO: A Phase 1/2/3, Randomized, Open-Label, Ascending-Dose, Delayed-Treatment Concurrent Control Clinical Study to Evaluate the Safety and Efficacy of AT132, an AAV8-Delivered Gene Therapy in X-Linked Myotubular Myopathy (XLMTM) Patients
No longer recruiting/follow-up only
3-5 Years
NINDS
Early
18-EI-0068
An Investigation of Vitamin A Palmitate Supplementation in Patients with Reticular Pseudodrusen (RPD) and Delayed Dark Adaptation
Participants currently recruited/enrolled
50-125 Years
NEI
Early
18-EI-0067
An Investigation of Vitamin A Palmitate Supplementation in Patients with Age-Related Macular Degeneration (and without reticular pseudodrusen) and Delayed Dark Adaptation
Participants currently recruited/enrolled
50-125 Years
NEI
Early
18-CH-0001
Mirror Neuron Network Dysfunction as an Early Biomarker of Neurodevelopmental Disorder
Participants currently recruited/enrolled
0-65 Years
NICHD
Early
17-I-0067
Sanaria PfSPZ Challenge with Pyrimethamine Chemoprophylaxis (PfSPZ-CVac Approach): Phase 1 Dose Escalation Trial to Determine Safety and Development of Protective Efficacy after Exposure to Only Pre-erythrocytic Stages of Plasmodium falciparum
Completed Study; data analyses ongoing
18-50 Years
NIAID
Early
17-EI-0112
A Long-term Follow-up Study of Participants Enrolled in 11-EI-0147: Longitudinal Investigation of Dark Adaptation in Participants with Age-Related Macular Degeneration (DA_AMD)
Participants currently recruited/enrolled
50-125 Years
NEI
Early
17-C-0157
A Phase I Single-Arm Study of the Combination of Durvalumab (MEDI4736) and Vicineum (oportuzumab monatox, VB4-845) in Subjects with High-Grade Non-Muscle-Invasive Bladder Cancer Previously Treated with Bacillus Calmette-Gu(SqrRoot)(Copyright)rin (BCG)
Participants currently recruited/enrolled
18-125 Years
NCI
Early
17-C-0137
Leukapheresis for CAR or Adoptive Cell Therapy Manufacturing
Enrolling by Invitation
3-65 Years
NCI
Early
16-CC-0098
Pilot Study of Ultrasound Guided Focal Thermal Ablation of Prostate Cancer
Clinical hold/Recruitment or enrollment suspended
18-125 Years
CC
Early
15-H-0155
Hereditary Parkinson Disease Natural History Protocol
Completed Study; data analyses ongoing
18-80 Years
NHLBI
Early
15-H-0016
A Phase II Study Using ACP-196 in Patients with Relapsed/Refractory and Treatment Naive Deletion 17p CLL/SLL: Pharmacodynamic Assessment of BTK Inhibition and Anti-Tumor Response.
No longer recruiting/follow-up only
18-125 Years
NHLBI
Early
15-DK-0100
A Multidisciplinary Approach to Deciphering the Mechanisms Involved In Microbial Translocation Across the Spectrum of HCV Associated Liver Fibrosis
Completed Study; data analyses ongoing
18-125 Years
NIDDK
Early
15-AA-0127
(Epi)genetic Modulators of Fear Extinction in Alcohol Dependence
Participants currently recruited/enrolled
21-65 Years
NIAAA
Early
14-C-0163
Transformation of Plexiform Neurofibromas to Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis Type 1: Clinical, Histopathologic, and Genomic Analysis
Completed Study; data analyses ongoing
10-125 Years
NCI
Early
14-C-0007
Phase II Trial of the Gamma-Secretase Inhibitor Nirogacestat (PF-03084014) in Adults with Desmoid Tumors/Aggressive Fibromatosis
No longer recruiting/follow-up only
18-125 Years
NCI
Early
13-HG-0053
The NIH Mini Study: Metabolism, INfection and Immunity in Inborn Errors of Mitochondrial Metabolism
Participants currently recruited/enrolled
2-125 Years
NHGRI
Encephalopathy
13-H-0065
Human Translational Studies of Inflammation and Cardiometabolic Diseases: The Psoriasis, Atherosclerosis and Cardiometabolic Disease (PACI) Initiative
No longer recruiting/follow-up only
18-125 Years
NHLBI
Early
13-EI-0049
Pathogenesis and Genetics of Microphthalmia, Anophthalmia and Uveal Coloboma ( MAC)
Participants currently recruited/enrolled
1-125 Years
NEI
Early
13-DK-0090
Identifying Risk for Diabetes and Heart Disease in Women: A Study of African-American, African and White Federal Employees and Contractors
Completed Study; data analyses ongoing
25-65 Years
NIDDK
Early
13-D-0033
Diagnosis and Treatment of Patients in Need of Third Molar Removal and Oral Specimen Acquisition
Participants currently recruited/enrolled
16-50 Years
NIDCR
Early
12-N-0095
Clinical and Molecular Manifestations of Neuromuscular and Neurogenetic Disorders of Childhood
Participants currently recruited/enrolled
0-125 Years
NINDS
Early
12-E-0049
The Molecular Basis of Inherited Reproductive Disorders
Participants currently recruited/enrolled
0-125 Years
NIEHS
Early
12-C-0081
Phase I/II Study of Cediranib and Olaparib in Combination for Treatment of Recurrent Papillary-Serous Ovarian, Fallopian Tube, or Peritoneal Cancer or for Treatment of Recurrent Triple-Negative Breast Cancer
No longer recruiting/follow-up only
18-125 Years
NCI
Early
11-M-0251
A Longitudinal Investigation of the Endocrine and Neurobiologic Events Accompanying Puberty
Participants currently recruited/enrolled
7-35 Years
NIMH
Early
11-I-0007
Lentiviral Gene Transfer for Treatment of Children Older Than 2 Years of Age with X-Linked Severe Combined Immunodeficiency
Clinical hold/Recruitment or enrollment suspended
2-40 Years
NIAID
Early
11-H-0046
Cross-Sectional Characterization of Idiopathic Bronchiectasis
Completed Study; data analyses ongoing
18-125 Years
NHLBI
Early
11-EI-0147
Longitudinal Investigation of Dark Adaptation in Participants with Age-Related Macular Degeneration
Participants currently recruited/enrolled
50-125 Years
NEI
Early
11-C-0033
Extended Follow-up of High Ovarian Cancer Risk Cohort from 02C0268 (GOG-199)
Completed Study; data analyses ongoing
18-100 Years
NCI
Early
10-I-0139
Searching for Persistence of Infection in Lyme Disease
Completed Study; data analyses ongoing
18-125 Years
NIAID
Early
10-DK-0102
Clinical and Genetic Studies in Familial Non-Medullary Thyroid Cancer
Participants currently recruited/enrolled
7-125 Years
NIDDK
Early
10-CC-0149
Comparing Expectorated and Induced Sputum and Pharyngeal Swabs for Cultures, AFB Smears, and Cytokines in Pulmonary Nontuberculous Mycobacterial Infection
Completed Study; data analyses ongoing
18-80 Years
CC
Early
10-AG-0423
A Pilot Study of Exendin-4 in Alzheimer's Disease
Completed Study; data analyses ongoing
60-125 Years
NIA
Early
09-C-0005
Randomized Trial of Cladribine (CdA) with Simultaneous or Delayed Rituximab to Eliminate Hairy Cell Leukemia Minimal Residual Disease
Participants currently recruited/enrolled
18-125 Years
NCI
Early
08-DK-0173
A Trial of Segmental Stiffening Wires to Improve the Efficiency and Patient Tolerability of Colonoscopy
Completed Study; data analyses ongoing
40-80 Years
NIDDK
Early
08-DK-0098
Natural History of Familial Carcinoid Tumor
Participants currently recruited/enrolled
18-125 Years
NIDDK
Early
06-M-0065
Neurodevelopmental and Behavioral Phenotyping Screening Protocol
Participants currently recruited/enrolled
0-125 Years
NIMH
Early
06-CH-0011
Natural History Study of Patients with Excess Androgen
Participants currently recruited/enrolled
0-99 Years
NICHD
Early
03-H-0282
Characterization of Cardiac Function in Subjects with Hereditary Hemochromatosis Who Are New York Heart Association Functional Class I
Completed Study; data analyses ongoing
21-100 Years
NHLBI
Early
03-DK-0257
Phase II Trial of Effect of Metreleptin Therapy in Severe Insulin Resistance
No longer recruiting/follow-up only
5-125 Years
NIDDK
Early
02-I-0202
Leukapheresis Procedures to Obtain Plasma and Lymphocytes for Research Studies on Antiretroviral-Naive HIV-Infected Patients
Participants currently recruited/enrolled
18-125 Years
NIAID
Early
02-CH-0278
Dyadic Interactions in Depressed and Non-Depressed Mothers with Their Infants
Completed Study; data analyses ongoing
0-125 Years
NICHD
Early
02-C-0268
Prospective Study of Prophylactic Salpingo-Oophorectomy and Longitudinal CA-125 Screening Among Women at Increased Genetic Risk of Ovarian Cancer
Completed Study; data analyses ongoing
19-100 Years
NCI
Early
02-C-0052
Etiologic Investigation of Cancer Susceptibility in Inherited Bone Marrow Failure Syndromes: A Natural History Study
Participants currently recruited/enrolled
0-125 Years
NCI
Early
01-C-0009
Breast Imaging Screening Studies in Women at High Genetic Risk of Breast Cancer: Annual Follow-up Study
Completed Study; data analyses ongoing
18-100 Years
NCI
Early
97-DC-0057
Genetic Studies of Stuttering
Completed Study; data analyses ongoing
6-125 Years
NIDCD
Early
92-I-0125
A Study of Viral Burden in Peripheral Blood Versus Lymphoid and Bone Marrow Tissue in HIV-Infected Individuals
Participants currently recruited/enrolled
18-125 Years
NIAID
Early
88-I-0172
A Phase III Study with Long-Term Follow-Up of Zidovudine Versus Zidovudine and Alpha-Interferon Versus Alpha-Interferon in Patients with Early HIV Infection
No longer recruiting/follow-up only
18-125 Years
NIAID
Early
88-I-0083
Host Response to Infection and Treatment in the Filarial Diseases of Humans
Participants currently recruited/enrolled
3-100 Years
NIAID
Early
85-H-0105
Cardiovascular Evaluation of Homozygous Familial Hypercholesterolemia
Completed Study; data analyses ongoing
2-70 Years
NHLBI
Early
78-C-0039
Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of Cancer
No longer recruiting/follow-up only
0-125 Years
NCI
Early